<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
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<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAC6</accession>
    <name>A0A1Y4DAC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56153">
        <property type="protein sequence ID" value="OUO56153"/>
        <property type="gene ID" value="B5F75_05910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="155"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="25672" checksum="99C6E020E96B6A71" modified="2017-08-30" version="1">MNLTQKRITGLLAAGLVGTSGLQAYDWKQAQKNLSPKQQAIAQTAALSAVGNLEKLPAAFYQALDSGLTVNELKEIVLQLYAYTGFPRCLNAAGVLESVVKQRRAAGKEDVTGLFPQPIPAGTDKYELGKRNLEVLTASKLPSHPPVFIQGTDTFLKEHLFADIFERGVLTYPEREIATVSALAALGNVAPQLQAHISMAMNVGVSAPQIEGIMAVIKKAVGRKTAVSGLHALEAVLSAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAF1</accession>
    <name>A0A1Y4DAF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56204">
        <property type="protein sequence ID" value="OUO56204"/>
        <property type="gene ID" value="B5F75_06190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="316" mass="36789" checksum="7305EB8063F88DD2" modified="2017-08-30" version="1">MDSHFIPSSSKKNTAVVLGATGNLTFALGVVLKGLKRHSAALLERADVIIYYQNMDEACRRALNQITPCRFVEYHFPHMEGLRPKALRDYGEMTFVRYECFRFLYHYEYVLWLDADILIQEDIADIVQHIPHGIGFRREYYDERVRMNFTQDIAGFKMDAPHYNAGIMAISRQLPAKDFNALADWCYQKTAAITQYLVFPDQGILLLMCQHFGLTIDALPEAYNCEARRKASALKHAAIVHAVGHRKFWKYYYFDEWYQTYREWVKETGLVCQNDFPLLKKLGLLKYPLFQVAPNPGKHPLKLATYLLKALLRRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAG8</accession>
    <name>A0A1Y4DAG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56224">
        <property type="protein sequence ID" value="OUO56224"/>
        <property type="gene ID" value="B5F75_06290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="63"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="94"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="216"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="328" mass="36054" checksum="E5F816695463A3A2" modified="2017-08-30" version="1">MGHWPGFIMHTLLRRMFYAVLMGLIFACPAGALPIQTDDEILRDFMWSRFTSLPQQQRPKIGLALSAGGVRGFAHVGVLEVLDNAGVPIDMLAGTSMGSVVGSLYAAGLPTEKLWEISDHMSFEQITPDFNVMGLFRFLFAQKLPSSANLVNFFHEQIGDMRFEDLKTPFTCSAMDIKTGERVVFNSGPLAIAVRASMNIPGVFEPVQYRHRALVDGAVVDYLPVESVKLMGADYIIASVTPPDFASTTPQSVAAYLLRVGDVRGAAMIEESSQKANFVLTNRVLDTGTLELDKLHKAGEVGIKEANRHLGELQEDILLFTLPYVFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAM7</accession>
    <name>A0A1Y4DAM7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56106">
        <property type="protein sequence ID" value="OUO56106"/>
        <property type="gene ID" value="B5F75_05655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016657">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02140">
        <property type="entry name" value="Frm2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033877">
        <property type="entry name" value="Frm2/Hbn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43035">
        <property type="entry name" value="PTHR43035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="23008" checksum="AEC66163E821BDC8" modified="2017-08-30" version="1">MELKTDCFFQAVQNRRSRYALEAKSPIADDEIIRLVQESVRHAPSAFNSQGTRAVLLFGKRHSEFWALVLAELRRRVPADKFAPTEQKIASFAAAYGTVLFFEDWDTVEDLQRKFPTYQENFPLWAYQANALAEYVVWTALEQAGLGASLQHYNPLVDQAVQKTFDIPKNWKLIAQMPFGTPAAPAAEKTFLPIETRVKVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAP2</accession>
    <name>A0A1Y4DAP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamate synthase (NADPH), homotetrameric</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56274">
        <property type="protein sequence ID" value="OUO56274"/>
        <property type="gene ID" value="B5F75_06565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006004">
        <property type="entry name" value="Glut_synth_NADPH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01316">
        <property type="entry name" value="gltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="2">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="142"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="463" mass="49693" checksum="5740B90CFC18885C" modified="2017-08-30" version="1">MPNPSAPRHNGKQLDPEVRKHNFEEVAQIFTKEEAMAEADRCLHCKNAHCQANCPVGVQIPDFIALLKEGKVGEAASKIMETSLLPAICGRVCPQEKHCEGNCILKDRFGSVNIGMLERYTADTARKEGLLKAPKTAAPTGKKVACIGSGPSSIAAAAELARAGHEVTVFEALHAFGGVLRYGIPSFRLPREVIDHEIETVKSMGVKFVTDVLIGATEKVADLLKQFDAVYVGSGAGLPTMTGIPGENAVGVYSANEFLTRVNLMQAYKFPETDTPIQVGKHVAVLGGGNSAMDAARCAMRLGPDSVTIAYRRSAAEMPARAAEVEHAKEEGVQFEYLVTPKEVLMDDKGRVTGLKCTRNQLGEPDERGRRRPVEIPGSEFVMPVDTIIVAIGQKPNPIIAKTTPELKTTERGVLALDEEGKTTLPGVYAGGDIIRGGATVLLAMKDGIEAARRINAYLKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAQ2</accession>
    <name>A0A1Y4DAQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56284">
        <property type="protein sequence ID" value="OUO56284"/>
        <property type="gene ID" value="B5F75_06615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="150" mass="17225" checksum="9E9DD4C88B75AE7B" modified="2017-08-30" version="1">MIVSEFSCGGVILDGRKVLLVQVKNMKGKKIWTFPKGHIEPGETPRQAALREVLEETGYKAVIVRPMIRVKYAFTFQGNYVKKMVQWYLMKKLGRIGKHDASEILAIRWVSLIKARELVQYPSDIRLVDMLLASLHIEPAEEPETEMPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAQ4</accession>
    <name>A0A1Y4DAQ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotin carboxylase</fullName>
            <ecNumber evidence="5">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_05815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56136">
        <property type="protein sequence ID" value="OUO56136"/>
        <property type="gene ID" value="B5F75_05815"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="9"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="128"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="463" mass="50777" checksum="731B77081F6DFAE4" modified="2017-08-30" version="1">MSAKVTITPFKKVLIANRGEIALRVIRTLKEMGIKSVAVYSEADRNSLHVRMADEAVCIGAAPSPVSYLNIDAIVTAGKITGADAVHPGYGFLSENADFAAAVTKAGMTFIGPTAEAIEMLGVKSTAREIAVKAGVPITPGSDGVVGKNFREVARKIGFPIMIKASLGGGGKGMRACLKEEDLELMMKTAQGEAKANFGDDRVYFEKLVLNPRHIEVQVAGDNYGNVVAFAERDCSMQRRHQKLVEESPSPFVDPVTRQKLQEAACKLVKAAKYRGVGTVEFLMAQNKEFYFMEVNTRLQVEHPVTESVCGQDLVKMQIQIAQGEPLHLTQEEASVIKCHAIEHRINAEDSEKNFTPCPGTIEEWIPAGGLGVRVDSHMYTGYTIPSYYDSLIAKLIITAPDREHLLARCRRCLGEFIVGGVKTTIPFHQKIVNNEDFIRGNMDTGLIERMMAKEKEESESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAV4</accession>
    <name>A0A1Y4DAV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">B5F75_06905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56337">
        <property type="protein sequence ID" value="OUO56337"/>
        <property type="gene ID" value="B5F75_06905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="130" mass="14519" checksum="4F81C4CEDCB20642" modified="2017-08-30" version="1">MDPIADFLTRIRNANMKKKEKVDIPFSKIKTEIARILKEEGYIANFKAVHNETKGGVVRVFLKYTPDNECVIQGLKRVSKPGSRVYSSYNNIPKVRGAFGISILSTSKGLMTDAQAKAEKIGGELLCQVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAV7</accession>
    <name>A0A1Y4DAV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ORF">B5F75_06150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56196">
        <property type="protein sequence ID" value="OUO56196"/>
        <property type="gene ID" value="B5F75_06150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="491"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="661"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1047" mass="117671" checksum="DE923BD730024532" modified="2017-08-30" version="1">MTDKKQTFPSRYYGLPNGAAKAYFVCQKYLNRNQNALFVTSSDTDDFDNAAHEFAPRGAQVFHLPDTDTGRMDALYDLLSPASGPRVLSASYEALSLPLPSPQEFKARLFTVRRGDTLRRQELLDNLQAAGYTREDYAETPGQYAARGSVVDIFCLNRPEPLRLYFAGNRVDVISAFDLDTQNTKEHVDEAVVIPLAFSQTPATLADYTPGYTFIFDEPDKEFPLADYPGCAVTTLLPSADATDCGLKSNIAFNANMELLEHEVASLQERSMTVTICCLNRGELDRMTELTADYPHLKKAVFKISPLTQGFYSPEDHFALITSNEILDRRYNTSRVLKRFDVEGAKRVRFKELQAGDYVVHQEHGIGRYLGLEVLDKEENPTDCLVIEYRRGSRLYVPMYDFKKVQKYIGAGGKRPALSALGGVAWKDVKKRVKEEAQKAAKEILHLEALRQATPAPEVPGDPRIEQEFADSFPYVLTPGQEQAIRDTLHDLDLPKPMDRVLVGDVGFGKTEVAMRAALKVALSGKQVMVLVPTTILADQHYKTFSKRMAGFPVNVRMLCRFQTPKEQKAVIAELKSGVCDIIIGTHRLMSKDIEFHDLGLVIIDEEHRFGVKQKEKIRSKLTGVHSLLLSATPIPRTLNQSLSSLRDISLIDTPPRGRTPIKTVVTAWNNDLAAAAINQELARGGQVYYVYNSVQSMQSRYLFLKKLVPQARICMAHGQMDEKELEQTLWDFNNGKYDILLASTIIESGIDITNANTLIVENAQNFGLAQLYQLRGRIGRGSTKAYCYLFHPDWLFKNKEEPQDNFADLAAVYWKPKEEKDPTEEARKRLAALMEFGELGSGFRLALRDMEIRGAGDLLGVKQHGYVNEVGLSLYCDLVAAEVKKLKGERVERNLHAKVNLPVAAYIPPDYIPDDADRLRYYKELMSADETKTQALLAKLKDLSGPLPPEVVHLAELFRMSARAGALEIYHVDWLDGQLELLFTRRFKMPPTLPGELFNRFGADRVEFVKSKNGDGLRLTAPAGKDPVAFAREVLLFFEQILKPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAW6</accession>
    <name>A0A1Y4DAW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="9" type="ORF">B5F75_06940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56344">
        <property type="protein sequence ID" value="OUO56344"/>
        <property type="gene ID" value="B5F75_06940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="136" mass="15502" checksum="EC7C5A1AEF3D3322" modified="2017-08-30" version="1">MLMPKRVKYRKPFSAPRIKGNAKRGTEVVFGEFGLKALEPKWITARQIEAARITLSRFIKKKGKLWIRIFPDKAITKHPAETRMGKGKGAPEYWAAVVKPGRILFELEGASVEDTKRAMRLASDKLPIKTKLVTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAX9</accession>
    <name>A0A1Y4DAX9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56216">
        <property type="protein sequence ID" value="OUO56216"/>
        <property type="gene ID" value="B5F75_06250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013322872" evidence="1">
        <location>
            <begin position="26"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="428" mass="49052" checksum="015C37FB316E4B19" modified="2017-08-30" version="1">MKTTHFILPACLCCVFLLPSTPSCAQKGKTAKQIVAASTQPALTAPVRASLEKSLALPVAKTVEAALPSRQLPALTAAQEAAQAAFLKEQSRHANEIATIMNFSLNKKILNYSFTLEQERANARRLVSTLQTYQTLNLNELQENNLLEKMSGFLVNKSLQNYLLDSMVNKNYLQFLRDLANYYSLSVKFMTSYELRFIAAQDTREIFAQTALDYMKAHPHKMNLKLREIMKSPFVTGELKASLRSFIALNQILPQHESSFLTVLREAHKQHSNGLAHARTEQDITATIEIYRSSAKELEEFTKRYNRSPRWNAPLKERRLYNKLVLLIMHNQANHFKQVVPYIAHINQLLVQFPHVRMSANETMDRLQRFIQKNHRFPRSITEATEKIKVPEAELDLYESAFYWESKDKAFAAAAFELRKDLQNSANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB01</accession>
    <name>A0A1Y4DB01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PmbA_TldD_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56226">
        <property type="protein sequence ID" value="OUO56226"/>
        <property type="gene ID" value="B5F75_06300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012192786" description="PmbA_TldD_C domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="2">
        <location>
            <begin position="295"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="550" mass="62053" checksum="E87FE9EE5B27B50C" modified="2017-08-30" version="1">MKKFVFLFVFFWGGFCTAAAADVPDNMYFRAMQDEMKRSLSQLRVKGSPKPYYLAYRLRYMSNACSSASLGKLTENDTQPYWSLMAGAVLSAGTPKSDSMGFVNSLSSSYDPEKAYDVPNSYWGIRRAFWKLTDSGYVNALDRFEKKQAYKRQKNISKTEPDFASAPQGSFAEEISPFPAVPHAQMARLVEKLSAQGKDVPYLEDFSAQMCLIQRDLYYLNSNGGFYQYALPGSFVTLSASLRNREGYKEKISRKIYLPADHSWQENALMDATRQLLADAQGVYKAQKPEPYLGPVLLMPAAAADFLNELLVANLRNIEPLLSSASENDATAGSFRNKQGMRIMSNVVEVYDKPSLRTYKGLPLAGFMPVDDEGVKAQDLTVVSAGRLQQLPLSRRSTEQGRKSNGHARMSAYTLPREALSNVWIKPKHPLSALEMEQKLLERCRELDLEYCYILKEFPGWEDGEASVNLAERIYTKDGHKEPVFGIKVEDKTTRSLRDILAAGSDEEVFYPYDPDSRDYSLITPSLLVDEIELMPDDKKPDRKPFIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB49</accession>
    <name>A0A1Y4DB49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD-GYP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56035">
        <property type="protein sequence ID" value="OUO56035"/>
        <property type="gene ID" value="B5F75_07080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD-GYP" evidence="1">
        <location>
            <begin position="181"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="398" mass="44310" checksum="052C4F003231E04F" modified="2017-08-30" version="1">MQSFKPENSKLSAEEKLNLLVEFGARISCELRLDKLLDIIGQQITKMLDVGRCTIYLKDVEKNELWSKIAQGRGLEHTEIRVPLNGNGVISLVARTGETINLPNAYEDPRFSMDVDMVTDFRTHSMLAIPLKNNSGKVLGVFQVANKSDGTAFDKKDEGILLLLATFAGSAIEIAKLYQDVHVAQLETIYRLAVTAEYRDQQDTRAHLKNISIISYLLALALGMSKKDSELIKNASPLHDIGKVALADNILLKPGKLTPEEFEIMKSHTIYGGRILEGAHSKVLKIAHKMACYHHEKWNGSGYPKGLKGEEIPIEARIITVADVFDALCVFRVYKKAWPTDEAYAYILGESGKSFDPHVVAAFKKIYPSVRKLYANISVNQPKPQTADVPAGEKKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB94</accession>
    <name>A0A1Y4DB94_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">B5F75_06900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56336">
        <property type="protein sequence ID" value="OUO56336"/>
        <property type="gene ID" value="B5F75_06900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="92"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="183" mass="19450" checksum="A40D300477C6E9D5" modified="2017-08-30" version="1">MSRIGKKIINIPAKTKVEIKDNVITATGALGTLSYTIPEGITPKMEGAALTFSIPENRVKELNALHGTTRANVFNIIEGVTNGFSKTLEINGLGYRANVAGQKLNLELGFSHPVNLDIPAGLTVVVDPKSGAVTIKGSDKFKVGDFAAKIRRIRPPEPYKGSGIKYQGEHIVRKAGKTAAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBM1</accession>
    <name>A0A1Y4DBM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56553">
        <property type="protein sequence ID" value="OUO56553"/>
        <property type="gene ID" value="B5F75_04995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="69" mass="7708" checksum="B1920CCE6370967F" modified="2017-08-30" version="1">MPIFSLRPTGSKVKLAAGQPFIRWDGEPKILTLLTQTAFYLLQYSCAFLAELRNLDVTEPARRVRGAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN1</accession>
    <name>A0A1Y4DBN1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_04590</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56476">
        <property type="protein sequence ID" value="OUO56476"/>
        <property type="gene ID" value="B5F75_04590"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="106"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="235"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="256"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="277" mass="29884" checksum="33C3CA4827A7B938" modified="2017-08-30" version="1">MILDKIIELALLEDLSLGDITSDTIFTPENRAKAVIRAKEDLVLCGMETAREVFAAVDPQVRFTPLKKDGDDVKKGEEVLALEGRTLSILKAERTALNFMQRMSGIATAARAYAAVGKKYGVMIVDTRKTQPGLRRLDKYAVRTGGARNHRISLADSVMIKDNHIAAAGSITAAVAKIKSVIGHTPKIEVETTNLDEVKEALAAGADIIMLDNMTPEQVRVCKKEIAGRAIIEVSGGVNKDNLEAYCQAGPDVISMGALTHSVPAKDLSLKIVQYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN5</accession>
    <name>A0A1Y4DBN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56486">
        <property type="protein sequence ID" value="OUO56486"/>
        <property type="gene ID" value="B5F75_04645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="135"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="576"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="632"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="1586"/>
            <end position="1642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1700" mass="191655" checksum="8A1B5B4F5343D874" modified="2017-08-30" version="1">MSNNFFSFFSKKDLPAEQVIKTLTPEMLAFLQQFPTAILLLNATGKIVFANAGAASVLRTEISDLNGTGVERLGLTMEKVRAMAEEKEPNKTIIQLVNREADAVYVSAGASFLASTPFIMLTLEFVPHFKQLNAEKSFLSSVINNYPVAVTVQNLAGVCTLWNTAAEKIFGFKAEQTHNHSVYEFLPKEIVASVQRLDEQVRDKQRPRENVLLSYKDAKGEERTLSVTKVFTPSENNKNKAILTIYEDVTMRQRYEQDLLQNRTLLRAVLDNVPLGLYTRDCDNQMTFFNRQSMKVLGETDVKCVNSPHPHQDKDVVSFHYTREQQVLSEGKIKDYPEEPYVDHAGNEKILHMIKVPLMDAGPKPLVLTIVEDITDRRRQEKEVARANSFLSAIVQNAPIGLYARAADGRMLLRNKQCEEIFGEVSDKAFDSTGSLPHETPEQVHEYIARERALLESGKTLDIPEEEYLTGGGEKKLLHMVKVPVSEEGNGEPQFVVTLVEDITEKRAQERALVETKNFLQTLLDQVPVAIYARGLDDKMSFVNRRAHELFPDEQEYLAKDDFYGQREKAIFKDGKTVEFPEEWYTTLRGNKILLHLIKAPVFDKEGKPFMVLTVADDITEKKAQEKAIIDAKNFLQTVINNLPVSLSVKDYDGKYILWNKKSEELFGVMAESVIGRTSYRVDINKDQAEFLREADLRVFESKKEQDIPQELISTANEGVKIMHTVKTPVFNVDGTPNCLLVVSEDITAKTKMEKQIREASDKNTLLVENAREGIIILEDGKIIYANRALCHILNYEDVKEVTGKKILDMVAEDHQMFLKDKYDAVVSGADDASSAIDVHFLKKGGQEVETEFAAVASKYLGRRIVLCFVRDVTSSNRMLREVKTERECFRAAFEKSVTPAFILSHKGYISVMNEACRKMFDFTDADKNFYRNVYMKPAVSLAARKQLRAGQPAHMDYVFDFDRAAKMFPGRIEGTGKLPLSVSFVPINKRDAKDGTVEADYVVFLERKEAKSAPVVPPPPAAPKQPEAPAAPKPQEHTAPKPPAPPMIISKTSQEMLVLPNSEPYALCGDGWKIEVCNDLFCSLCQLEEDELIGQDLRRLFDADSLPRLEEDLKTLQQDGSLANREYHINLASGLENTAIRLTAVKEADGRYLFVLRNMAFHRQIMKILEERSAQLNALLEATEGVVFSVLFENGRFGHIEQANKFLSRKLGFTHDELVHMPFRDLFFDKEHNSSRCKEILDHAQEELALEGKTSFKLSVRKKDGSAFEAHVVLTALDLPSKDAALVVVRDLSEELDEVSKDSKEAQELKSVRQALPGLYLKTDSDGRVLEVYSNLAYFDNDQASKVFLDKKPGTYWPQEAASRALFAIKEALSINVSTRFEFEWRVSGTLHYFEATVTPITGRAETVLWVKDMSEQHAYDEKIHELYRLASEPGLSITEQVDKILAFGLKTFPADVGLVIRFDQGKLGLESHIVYVTDNDFNIERYMTFPVEECLVDVPDGNVVIFPDLSSATCTHCLHKEKGFGSLLAAPLYVSGKVQGALCFASRAPRHDFGQGAEELMGIMSRLLSLRIELRQTGKMLSEASRSLARTLEYVEMPAVMMDLDYTITFVNKPFLEITGRRTSNIVGRDFFTEVIRNEDISKRMFKAAENSAAGNAFQVRMDLLHENGLYEDTGWDVFACKDSDGKIDGYALIASES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP2</accession>
    <name>A0A1Y4DBP2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56567">
        <property type="protein sequence ID" value="OUO56567"/>
        <property type="gene ID" value="B5F75_05075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025707">
        <property type="entry name" value="DNA_bp_PD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016702">
        <property type="entry name" value="DNA_bp_PD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="142" mass="15884" checksum="DD91862BF0EBC7C6" modified="2017-08-30" version="1">MAEEKPYLTGRTYLFRLPKGKDLLESLADFCHDNQVKCGIVNVIGSVSNATIGCYDQNKKKYEKTVINQEMELISLCGNISIQDNRPQVHAHVVMAGKDNQAIGGHLFPGTKIYVCEAYIQELVGEPKVRRSDKVTKLSLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBS8</accession>
    <name>A0A1Y4DBS8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PolyA_pol domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56607">
        <property type="protein sequence ID" value="OUO56607"/>
        <property type="gene ID" value="B5F75_05290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="4">
        <location>
            <begin position="27"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="370" mass="42054" checksum="4CE514C026C3EE58" modified="2017-08-30" version="1">MTVTIPKSYREPLYTIGEYAQKLGLKAWVVGGAVRDFYLKKNTLDIDLAFDGNQESVAGFCVKRWGGAKRKFSQFGTFRVQLDNGLKLDMVRARKESYPHPGALPVVAFSKEMKDDLFRRDFTTNAWCLSILPKNFGQSYDPFGAQKDIDAGVVRILHDKSFLDDPTRMYRAVRFAGRFGWRLAPKTERLLQAAVKEEYPLLLTRERFCQEFLKVLKEKRVKEIFGLMEKYDMLKFAWPGLRWNDALDSVSTPAERMGVLACSLGPSGEDFVRTLHLPKDKAQEIVSAWKIAQEQMCPLGPLSEMQKTVLKTVFPKLPLQALEPCFVRGGELKNLGLSGRKISGALGRVRKAQWNGEIKSREEAIAFLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW1</accession>
    <name>A0A1Y4DBW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpmE</name>
        <name evidence="9" type="ORF">B5F75_05395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56627">
        <property type="protein sequence ID" value="OUO56627"/>
        <property type="gene ID" value="B5F75_05395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12644" checksum="B80C5B8FB4616020" modified="2017-08-30" version="1">MKEKIHPTYEFVEAVCACGNRFMTRSTAKTLKLDICSACHPFFTGKQKLLDTEGMVEKFNKRFAKTEGKTMVRKPKTEVKAKAKLVKKPVVAKKAAAKKPAKKAAAKKAEAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW2</accession>
    <name>A0A1Y4DBW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56634">
        <property type="protein sequence ID" value="OUO56634"/>
        <property type="gene ID" value="B5F75_05435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="356" mass="40372" checksum="C5506D3D2DC1B2B2" modified="2017-08-30" version="1">MKEKIICVSTPSGRTYYRAIPLAKEFLDKEQNIVNTTGELPDGEITEFNVSSATIKNLLGGKLNGKFEVINLTNNTVTYSEQYENGKLVSITERNLNTPTDVQTKKEKAVRNYPGTVLKSSKNTNSFYCNGQEVAEETLASNGATLEILGQIPDGEVKEFNDNGLVKTEAHYKGNKLNGTVKRYSDSGVLLSQEEYVNGILQGTAEYFNPTKNDMLHAQCTYKNSFLEGRRTVTQKDGTLRQEETYKHGRLNGKRISYYPNGCKEIEENYEDGKRQGERLLYFPTGSLWYRENYNNGRLDGERFGYFASGKTRLEEFYTEGLLEGRRCIYAENGELLSAEEYHWGSLVHNTDRTTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW4</accession>
    <name>A0A1Y4DBW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ORF">B5F75_06945</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56345">
        <property type="protein sequence ID" value="OUO56345"/>
        <property type="gene ID" value="B5F75_06945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="243" mass="27182" checksum="AB72301E9A8554DA" modified="2017-08-30" version="1">MGHKIHPRSIRLGYIQDWRSKWFAPKNMPALIMEDFQIRKLIDDKFKMAAVSYVGIERAGAFLRINIHTARPGVVIGKKGADIEALRKEIEAMTGSKTFVNVMEIKNPETDAQLVAQNIAMQLEKRAHYGAAIKKAIEKAMSGKALGIKIMVSGRLGGAEIARTEWKREGRVPLHTLCADIDYGFTEANTISGKIGIKVWIFKRTHFAKSPKEIMNELKKHRDMENASAQVVTEPVAAAEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBX2</accession>
    <name>A0A1Y4DBX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mur_ligase_M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56623">
        <property type="protein sequence ID" value="OUO56623"/>
        <property type="gene ID" value="B5F75_05375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="4">
        <location>
            <begin position="44"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="415" mass="45975" checksum="09555BFE79D7B0B3" modified="2017-08-30" version="1">MSFDIVFNYILKRSGIGCGAGLDGFARLLERLGNPQNRYKIIHVAGTNGKGSVCTMLARTLECAGYKTGLFVSPHLVSATERIQLNGVPVSKQRFSQAVLEVFQEEEEELNFFEILTAAALVYFAKQQAEYVVLETGMGGRKDPTNVCRPVLTLITSIGLDHMQYLGSSLSQIAYEKAGIIKPGVPVISGTVNPAARDVIRKIAKEKKAPLVFVGEGEPFYEYAYDFVNNQTVLHTRERQEWLLHALGRRQTINACVVYQAAKRLKLPEAAVRKGLETVVLPGRFEMVRLGENTFILDGAHNPQAVELLMEFWQKTPFTHDTALLCGFMKDKDYKKMLSLLCPHFSRIILTVPPSVRGAGEPDLLAALPKQAKVLFEPNWKKALALARKSPRILCTGSFYLVGAVRGKLPVPDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY4</accession>
    <name>A0A1Y4DBY4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56633">
        <property type="protein sequence ID" value="OUO56633"/>
        <property type="gene ID" value="B5F75_05430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="140" mass="15612" checksum="4DC518DD7A3E711F" modified="2017-08-30" version="1">MTELLVVVIVIGVLAAVVLPKFSKVIETRKTTEAEELMAAVRIEQEKRCALDKDYISDLSKLSDIVPSKETKNFVYNASTTGIEAQSKGKYGYTLKMPSYRDGRLCCENEEECLKLNKDYPLCSELIARADYQSGEECAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCD6</accession>
    <name>A0A1Y4DCD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pal</name>
        <name evidence="9" type="ORF">B5F75_06435</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56252">
        <property type="protein sequence ID" value="OUO56252"/>
        <property type="gene ID" value="B5F75_06435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0564">Palmitate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013322876" description="Peptidoglycan-associated protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="8">
        <location>
            <begin position="50"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="169" mass="18153" checksum="B6A2821A02FB30A5" modified="2017-08-30" version="1">MKNLLRVVLVLALAAGLTACKKNVKDDANADLTAGTGTEMVLEETTVTEEVPAQEVSLGVVHFALDKYNLSAEARKIVEANVQAIKSAGAVASYKVTVEGNCDDRGTIAYNIALGQKRADEVKAYYVRLGIPAANITTVSYGEEKPVCYEATQSCWAKNRRADTLLKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG1</accession>
    <name>A0A1Y4DCG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">[FeFe] hydrogenase H-cluster radical SAM maturase HydG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56565">
        <property type="protein sequence ID" value="OUO56565"/>
        <property type="gene ID" value="B5F75_05065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044271">
        <property type="term" value="P:cellular nitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018130">
        <property type="term" value="P:heterocycle biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901362">
        <property type="term" value="P:organic cyclic compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042364">
        <property type="term" value="P:water-soluble vitamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024007">
        <property type="entry name" value="FeFe-hyd_mat_HydG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034428">
        <property type="entry name" value="ThiH/NoCL/HydG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583">
        <property type="entry name" value="PTHR43583"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43583:SF2">
        <property type="entry name" value="PTHR43583:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00319">
        <property type="entry name" value="Fe_hydrogenase_maturase_(HydG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03955">
        <property type="entry name" value="rSAM_HydG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="70"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="460" mass="51782" checksum="D1326F49485DF733" modified="2017-08-30" version="1">MIIDDEKLQRTLEKAKSHSDSEVTEILKKARELKGISLEEAAVLLNLTDKKLLNDLFNTAKYVKEAIYGNRIVLFAPLYISNICTNECIYCAFRRSNTHLKRHASTQDEIRQEVTALLQQGHKRILMVAGEAYPGGGLQYVYDSIKTIYDTRWNGQNIRRVNVNIAPLTEPEFEQLKKCNIGTYQLFQETYHKETYAKLHIAGAKKDYQFRLDAMDRALQAGINDVGIGPLLGLYDHKYEILATLEHSWYLDKTYGVGPHTISIPRIEPAEGSDFSQHPNDVLTDDDFKKCVAVLRLAVPYTGIILSTRESPAMRNACLELGVSQISAASRVNPGGYSYDKQNGSQFTLTDDRSLAEVIDAVVDAKHMPSFCTGCYRLGRVGKDFMDMAKPGLIKTHCLPNAMFTFAEYLEDFAPAPLKAKGYALIDSTAKDAFPQDSPIHKMIEDNLKAIKEGKRDLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG8</accession>
    <name>A0A1Y4DCG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histone H1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56575">
        <property type="protein sequence ID" value="OUO56575"/>
        <property type="gene ID" value="B5F75_05115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005819">
        <property type="entry name" value="H1/H5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00624">
        <property type="entry name" value="HISTONEH5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="84" mass="8822" checksum="F624461E971AC83E" modified="2017-08-30" version="1">MAVKKTVKKAAAKKPAKKVTVKKAAVKKPAKKACAKKACAKKACAKKTVKKVAVKKAAVKKTAAKKPAAKKTVKKAVKKVAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCJ3</accession>
    <name>A0A1Y4DCJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56874">
        <property type="protein sequence ID" value="OUO56874"/>
        <property type="gene ID" value="B5F75_03240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="592" mass="66106" checksum="392464E9764D8E5E" modified="2017-08-30" version="1">MNNNKRLFQLGILIIALLAIGLAWLRISAYHQQVSPAGAANQIRQEQRRVIADLKAEEILGIDPQQSLSKEEKRALAVQWYARRPDLSIRRPGHAEADAFSARPYARPQKGVRGSFGAQSSAVSSYRPKGLSAADYGRYGSSSGSYTGGADGQQAGVYRPSVQEQMQAERERSFAPFMASVPKEQQKRLQMQLKGLSSGINRAVAKALLPKSKKDANIEKYLQRHASPEAAHAGPFAPVLEQVSAQKAGVVHSMGQAFGQEAAQEASKVMDSFQSEMAAVVNAPGQTSEQIAEKVQQVAQKYEQKLQKMSEDNGFKKFEQERIEKDNLLKQEISKQYGEDLAAQAGAKIDEFREKDMLLARQGLPPEQYYEQQLANQSERRKALEDLIAKSGKSTKGLMEAEDEVEKQEVAQRLKDEEEGKTLARSYKAGEKELAAIDKSLSQERQEKLQTAGMVYGEDGARRIDAVYQKYYDEYMKIWQNPDSSKTDKQQASMKLRQDVNKQLEQIQNDPQMQEARLNRQVDSSLAQIMKDPGLRGASAEQKAALQERARPVLREMYEKVNEVVASDLPEAEKQKQIQQIQASAQQKLAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK5</accession>
    <name>A0A1Y4DCK5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="11" type="ORF">B5F75_02730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56776">
        <property type="protein sequence ID" value="OUO56776"/>
        <property type="gene ID" value="B5F75_02730"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="24"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="355"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="399" mass="43190" checksum="DECDBC263512F975" modified="2017-08-30" version="1">MNFDSIKKIQDVDLKNKKVLVRVDYNVPLKDGKVDNNKRIVATEKTIKHLLDNNCRIVLIAHLGRPKGKVCPEFSLAPVAAEVEKLFGVPVHFAKDCVGPEADKVVAETKNGEIALLENLRFHPEEEKNDPEFAKQLAKHGEVFVQEAFGTVHRAHASTSAIADFLPGCAGYLVQKEVEFLGKALENPARPFAAVVGGAKVSDKIMLLNNLMDKVNVLVIGGGMAYTFLKVQGHEIGKSLFDAEKEDEAKAVLAKAQEKGVKILLPVDHICGKEFAETAEPVTVEDINIPADLMGMDIGPKTMAMFREELLKCKTIFWNGPMGVFEFPNFAKGSFAIAQAMIDATKAGATTIIGGGDSVNVLKKGKFNQKELSHVSTGGGASMEFVEGKELPGLVALAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCL3</accession>
    <name>A0A1Y4DCL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_02780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56786">
        <property type="protein sequence ID" value="OUO56786"/>
        <property type="gene ID" value="B5F75_02780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="4">
        <location>
            <begin position="521"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="752" mass="79081" checksum="77AA8DAAC82E635F" modified="2017-08-30" version="1">MKKFLKLCFKIALVLVILGVAALVALRLMFPPEKLKSMALEYAKNNLQREISFDGISLNLVGVTLDNFAISENTTFQNGTFAKADKLVVKIALKPLFKKRVEIATVQLDGLDVNVIKKQDGSFNFDTLIPASDPAAAASAEQPAQPAAASSSAFVLLADKISANDCSFSYHDLQTGMKASVDKLNLEINQLDLAEPFDVKINFNTFYQQKNGPAVAVPVNIALRVFLSNLDMKNAYVTVNDISASYKTVKFQLKGGVRDFTAPQADLTGTLSGISNAIFADFLPNLPDFSLPVINMNLKAAADLEKSSATISQAKLSVMDSALSAYGTVGWNGPAPTYSVNADLTTNLAQIVQMTSTVAGFNPGGVISGSFKATDKNEGKDISGSVTFKDISAMYEPFTVSQLNGTVNIASLDNISSNSLTGLLNGEKFTSSFSYQNIKDVMNVVLNLDLAKFTLKELPAAAAETTAEAAPQTAAEDSASQEAQPAAQTTAASSGNLLLNLKANIKVGPIEVPYFRADGFSLTANLTDITDTMTKANGQVSFNLQPGAITNLDSFVKENKIVKILLLPISIVRKVAGALNVELFPAQENAQKGEISFTSGEGVYTFVNGVMRVDKTTFNSQVTDISGSGTINFLTQALDMKVSATVLTSQTPVVIKIGGTMDNPSGKLDVVSTVGSLVGGILNYKTSGKVVSGTANAAGNVASGAVKTTGKVAATAANAAADTVKGTVNAAKDALKGLGGLFKKSDSSEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ5</accession>
    <name>A0A1Y4DCQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56806">
        <property type="protein sequence ID" value="OUO56806"/>
        <property type="gene ID" value="B5F75_02885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010985300" evidence="2">
        <location>
            <begin position="22"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="440" mass="48787" checksum="DD11C3A599A70A9D" modified="2017-08-30" version="1">MRKIFISLFIFMFAFPGAAMAQGKSKMITSTVKATTEKSVSGLKKVPLETSLPKLKIVAPAAGTLRQAPVVPNMTKAAILEKLQELQQEVNSLRKANIELQASATSNAIPSDAYIFQSRETNDMSVRSNLFSGSVFSIEYNGKKEVYGVVAAHAIAGDPLEKYSLHKTFTAIIYKNGLQKLVPVEVVAVSPQSMLDIALVKFPAEIEPLLLPYRLGDITDEINLISKGFSGPVPTAVTNREIIACTPLSIRTTMPLERMARPGLCGSAVLNSKNELVGIHTGSIYSTAGEEADIAYATPSYYLKNLVEAYHNPGKGTFPFIVNGQKIADFAIEEYVTHLSLSDANNHMLWQLQVPSKLPYSKLQEALENYPQAKFLQITTRHASWTEDGYAFVENRTKTDRNKKTTYTYDLQEQKLLTAFQSVYNPTFRQRKTIKIYPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ7</accession>
    <name>A0A1Y4DCQ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56645">
        <property type="protein sequence ID" value="OUO56645"/>
        <property type="gene ID" value="B5F75_05495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="796" mass="89008" checksum="0ACBE33633D6F4EB" modified="2017-08-30" version="1">MITLPAALAAKLKSNDLRGINPIVWLYRNKWDAQANTFAPETTPIDITEQVIKCGTLSTKLDVGEINEYTASNVTLTISDPQNHFVEGTPKSYFPEGYQIYGSRIELYAGTDTNNMTPLFYGVIRSLPNHKPEEYQQDISVVSALELLDDVEAKDFSTPYTGEKLTLDHRDDDAGPVYRTANTGVGGFNAVYANGSVLVEGVDYEVSQLGEYLKPALVEIINEEFYSATITADYYCWRRNLTVEEIMGGLLDVSKWPDDKRDIQHVIWNSLVRQPLSADVRFGLGYYQNDEGEYISNWLNVRDNAWANTTARDENTYTRRSVFSANWETEFTLRIDDLSGATSGFNGSYAVGSGTSNWLHGINNGIVIAAVRVDNQAPRGLYIGVGRAVNANLSYSYRTDVYSPVSYLEIAVKIRKINNQITVFFGGKQVAQFNNANFNVDREVMYGSRNQRISNLGQVWRMLDSNGNAVSPDLSTPSIISNVLELGDEGGYWGAVSATLEGEGGQYQNEVFISSDGQNFTSAGNFDIGSDIGRSENYLYFALKISSPPPASFNISNLIVFKYATGMVIDFINLEGQTVLEVIQDLALITGYEFGIDRNNVFFFRPRQTSTQPVAVLDELELVKIDTVTRNFNELATKLTLTFAAAPLEFYANTGTRPTPVDKYGVIEKEIDKPQLINYDNPELAQAIGPQLLAIYSELPNIITCTGKLNLALELGDIVNLKREMPLTINPEASDYTKYEGLNTFYRACKITGLNYDFQKRQIKYTLRDVSNNNNAPVRNFYEYQTKFPTPLDYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS5</accession>
    <name>A0A1Y4DCS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56826">
        <property type="protein sequence ID" value="OUO56826"/>
        <property type="gene ID" value="B5F75_02990"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="93"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="171" mass="18517" checksum="887A217CAB4DAAD0" modified="2017-08-30" version="1">MKKTATKKTAPAKKAKAAKTPAVKESPILKEVKQLYGFMQDNNLDTIEYDQKGLYLRLVKAKPAMVPVPVSVGGSAVAASGAHPAVPAQEQYKEVIKSSLMGIFFRGSTPSAPPFVKEGARVEKGDVICLIEAMKVFNEMRAEFPCIIKKVLVDNGKPVKQGDALFAIERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS6</accession>
    <name>A0A1Y4DCS6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56923">
        <property type="protein sequence ID" value="OUO56923"/>
        <property type="gene ID" value="B5F75_03510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="314" mass="36294" checksum="ABC0DD31AE0C43E3" modified="2017-08-30" version="1">MEKARFKKTPFHFMQYAALKTFCALFGLLPYKTAVWLGRKATGAVRFVMKKRFERSVYDIRRAFPQMTPAEARAVALESWRNMGGILAEFIKLTRMTPEEFKKHCRIIGAEKMLNAQGHTGGIIHIGHFTNWEAFGLAGAIYGVDKAVLAQRVDNPYVDEETNRLRNIFTGRTFYSNNEDKPFFACMRWLKKKKMLGILIDQNAGSSEVWIPFMGRIAAFSPITALLAIKMQVPVFPVRVWREKDGTIVSEVMDPVLPPKEYSMENARQFTKTLVGYYEDWLRANPGSWLWAHNRWKREAEGEAYLKNHPEERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCW7</accession>
    <name>A0A1Y4DCW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Preprotein translocase subunit YajC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_03680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YajC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56957">
        <property type="protein sequence ID" value="OUO56957"/>
        <property type="gene ID" value="B5F75_03680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="103" mass="11048" checksum="FBF08A1968D607D4" modified="2017-08-30" version="1">METTAQGGGMFFWLLLLVFAFVVIFLPARSQKKREQELMMKVNALQKGDQVIIPGGIIGTVAGFKDNAIEVKIAENVKLTVLKTAIVGFPADAQLAAQEGGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD12</accession>
    <name>A0A1Y4DD12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57013">
        <property type="protein sequence ID" value="OUO57013"/>
        <property type="gene ID" value="B5F75_03975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="552"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="766" mass="84880" checksum="666F982DC83FB4B5" modified="2017-08-30" version="1">MASKKTLSRTKKSARAAQASVAAGGREIPFLHKALVHVTGWLCLLVSISFFTATYDTAQVKLTLLHCGAVVLFALWSALQLAERKNPFTRQNLPFLLPVFAYLAWNIVSFIGAPYKMEAAEEFIRLLMYGAITLLIACQFRRQDVKTVTRYILAAAWISFGYALLQIIDGFFPGADFMPWRGFFTRRVFSTHANPNFFGAFAVFASCLAAAQYLLTRQKKLLALLAAGLLGVFFTESKGAWLAYAAAAACFAGLYTNFFLSGAAKKYVKKINLAALCLLLLALAGAGFYTAKRFQSVSFRTFTWLSAWEMVQDSPVMGTGPGSFKIIYPAYRRPQIFYIENSHNTETQHAENEYLEQWATTGTVGLAVFLWLIGFIFYCAVRNLKQPLPAPSDEPLRERNLYLLGYASAFFGLMVHAGVDISIRFASSGLFFAVFCGVILALCQPEESAAPAGEKASAPAWPWAARLLLCTALVYGGWHTAAQFAQVTRVLQAGSFGEGLLIAVAWAVFLFCLAGTAYVYLRAAFLGKRALPCFVLAASVPFLIFFYGFFQANHYYSLGVSLVSKGNAEGALGYFTKAVRLNPLLTEYRQFRANTFATTLQLTDSFSPDRGDRTAPSNDYERALADFAVVLKRAPNHSMVHQNIGQLYYAMAVRQAQSAGQAVNAAEYARLSQYARQNMEQAKRAFERSIKIDPVNPATYAFLTSIALMERNPEHAQQWIDAYRRGPAGVTEPEFLDKHRKNPQFDALQQQVDLMRASVGKSAHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD58</accession>
    <name>A0A1Y4DD58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56562">
        <property type="protein sequence ID" value="OUO56562"/>
        <property type="gene ID" value="B5F75_05045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="273" mass="30599" checksum="884C4026246D0871" modified="2017-08-30" version="1">MKKYDYYRPSASSLGRKKRVVRRQGSSFFFRFFLVVVLLLVVGCGGWLALSKGYRMLVNSQITDWHAKTISVTGVTGQINKEISALAAPYEGKAFSVKDAAALREAIVKRYPMLKGVSVSRGLLSGKLSVSAVHRKPIAKFVLPDDTIRYIDEDSTVYADPNPNLLEPVPFVELSGPVPEKLSPEFIDLVESTLKLNNELDFAFLQMDLKNNTVKMHMPDGCVIDFGPAVQLKRKADVAARILAYSREHYGELKSLDFHFFKYGKVFLTQTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD74</accession>
    <name>A0A1Y4DD74_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56582">
        <property type="protein sequence ID" value="OUO56582"/>
        <property type="gene ID" value="B5F75_05155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012486417" evidence="1">
        <location>
            <begin position="25"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="33247" checksum="60ECC20DF8C65FA6" modified="2017-08-30" version="1">MHNKKLFATVLGFFLLAGFMPLQAQLAKQGLQQIPRALGKNVIEESATAAAWKNFGGVLPSASAAAAAAKVEVAPASFKSQVAKKYPGAVAAYEQKVKNLSLQQSLRRVVELRGLTPPKGWPQKSEHSLTVSSLSGLTLDGYTGDCPTLPIPTSKIYLYRGMGLHESALRNVLKNGLRVQDSGKHSNDLDINMRLASMGTMPVSRQMMKDMDIRQTYLTPNAQETLHYAYMYSFEEGKIPVVVTVRGWRKGNSHHVIREDIPASDFVEVSALIQGPKGEPVWCRVDLADDGYSFVFTPYVPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD90</accession>
    <name>A0A1Y4DD90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56602">
        <property type="protein sequence ID" value="OUO56602"/>
        <property type="gene ID" value="B5F75_05265"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="2"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="281" mass="30924" checksum="D8592A3FFEF39E3B" modified="2017-08-30" version="1">MLLITGANGQLGRCLQEVMGEQKALYTDAAQLDITDPAALEAFTKSHLLQGVVNCAAYTDVDKAEEEPERAYQVNALGPAHLARLCARLQIPLVHISTDYVFDGTAHTPLTETDKACPLGVYGKTKRQGEEAVLGLAHTAAVIRTAWLYSPYGKNFVKTILELGRTRAEIRVVSDQIGSPTYAPHLAAAVVRVLECLQKGEKKLYHFTDEGVASWYDLAYYAVRQAGLNAQVLPIATREYPTRARRPAFSVLDKSRIKKETGIAIDHWTKGVDACLKKLSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD94</accession>
    <name>A0A1Y4DD94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56996">
        <property type="protein sequence ID" value="OUO56996"/>
        <property type="gene ID" value="B5F75_03875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="7"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="328" mass="35504" checksum="D21989F74727FC48" modified="2017-08-30" version="1">MNDCKNVWIFAEAQRGKLSPTALELLTAGRQLADDLGEKLCAVLLGYEVEKFAQDLFEHGADVVYVCDDKALENYLDDVYAKVLADMVQKYQPNKFLLPATNLGRSLSAKTAIFVGTGLTADATEVVINKADGQLYATRPTFGGNLMATITCTHTRPEMCSLRPMSYEKAPRQAGRTGEIVRFAFDPKKHTTLAKFVEFIKSQGDGMDLSEAEIIVAGGRGVGKAEGFELLHKLADRLGGAVAASRAPVDSGWIDYRYQVGLTGRTVKPKVYIACGISGQIQHMAGMSGSDVIVAINKDPEAPIMKVANYAVQGDLYDVVPAMLEALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD99</accession>
    <name>A0A1Y4DD99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="9" type="ORF">B5F75_03085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56845">
        <property type="protein sequence ID" value="OUO56845"/>
        <property type="gene ID" value="B5F75_03085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012260558" description="Endolytic murein transglycosylase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="321" mass="36660" checksum="8328186B37C08154" modified="2017-08-30" version="1">MKKFILLLCVCVCLLAGGCWAVKACFFSKGPLVVVKIEPGQSGSEVAHMLKEKGIIRSELLFKALLRLTSSARDLKAGRFDLRKNTSAFEVINCIKSGKCTHYEKVTFLEGWRSEEISELLAEKGITDARAFLDIVREKNLEGYLFPSTYLFAENTPAQKVVDEMLAQYRKNIAPLFRKYPTNLTERQVLTVASIVEREAVVHDERPKIAAVYLNRFRIGKRLEADPTVQYALGFNLKENRYWKKGLTYKDLRINSPYNTYRNAGLPPGPICNPSRESVLGVLNPEKNFDALYFVADRGGRHVFSKTFDEHRQNIRRIRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDC1</accession>
    <name>A0A1Y4DDC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="17" type="ORF">B5F75_03955</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57077">
        <property type="protein sequence ID" value="OUO57077"/>
        <property type="gene ID" value="B5F75_03955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="16">
        <location>
            <begin position="605"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="744"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="955"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="645"/>
            <end position="652"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO57077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="980" mass="109115" checksum="57483FF788B9AF14" modified="2017-08-30" version="1">MKSIKVIGAKGHNLKNVTVELPKDKMVVVTGLSGSGKSSLAFDTIYAEGQRRYVESMSAYARQFLELMEKPDVEHIEGLSPAISIEQRNPSKNPRSTVATVTEIYDYLRLLFARVGHRFCPQCGREVQSWSVQGIAQDILKKFNEKTVYILSPVVRGRAGTYEELFAKFKKDGYVKARVNGTVVSLEHTPSLERYKKHTIELVVDEIFVEEFDRERLVESLEAALKYAKGLVHVLETEGDKPREFTYSEENACAHCGIGFSELEPRLFSFNSPYGACPDCNGLGLKIEVAEDLVVPDPTLSINEGAIAAWDNPVTTRTHRWKNSWSGYYYDILKQVCRQNRINMNTPWNKLSKAQRDLLLYGTGGASYTSLISGGEQDFEGVITNLKRRYQESESDFVKEEVYTRFMREITCPTCHGKRLKPEALAVRVDGKNIHEIVAMQVSAAKAFFDQIHLSDKEKIIAKDVLKEIRARLEFLNSVGLSYLTLERKSQTLSGGEAQRIHLATQIGSGLTGVLYVLDEPTIGLHSRDNDRLIETLKNLRDLDNTLIIVEHDKDTILASDYVVELGPAAGENGGQIVAAEPTADFLRDEKSLTASYLNGRRMILPREELRKGNGKFLEIVGAKQFNLKNIDVKFPLGKFICVTGVSGSGKSTLIHQILYKALAQKFYGAKDAPGKHKEIKGLENIDKVIIVDQSPIGKTPRSNPATYTGVFSHIRDLFAEMPEAKRRGYKPGRFSFNVKGGRCEKCQGDGILKIQMQFLPDIYVKCEECDGKRFNEDTLQVKFKGKNIAEVLDMSVSQALEFFDSIPKIKRYLKTLNDVGLGYIKLGQAATTLSGGEAQRVKLADELSRKGTGKTLYILDEPTTGLHFADIDKLLQVLHGLADKGNTVLIIEHNLDVIKTADWIIDLGPEGGDKGGQIVVAGTPRQVAACPKSYTGKYLKPELDAVDKFLAQHPEQKLHAPKNAAAKKASSPVKKSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDD4</accession>
    <name>A0A1Y4DDD4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE family efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56885">
        <property type="protein sequence ID" value="OUO56885"/>
        <property type="gene ID" value="B5F75_03310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="456" mass="49757" checksum="B010C4066C6DE5E7" modified="2017-08-30" version="1">MKTKVSSKKPRKVIRRKLFNLTSPIFVETLLIMLTGTVDVFMLSRYSDETVAAGGVVNQLLNLVFILYGITTLGTSVLCAQYLGAKQKKNVAQVIGVSLLANLLMGLLVSAGLFFLARPSLQLMGLDESLIGYGISYMKIVGGFSFLQALSMTLSAILRSHNKAYYPMFVTLLINIVNVIGNYMLIFGNFGAPRLGITGAGISTSLSRLLAVGLLAYILFSKVTAVPSLKLFKPFPWDKIKNLLTIGLPAAGEQVSYNLSQVLITYFSVMLGTAALTARTYAMSIVMFSYVFAIAIGQGAAISIGHLIGEERDNAAFSVEKYSIKLAMLVTVCISVLTALVGTDIFKLLSSNPEVISIGATVLYIDVLLEIGRAVNITSVNSLNAAGDVMYPFITGIIVMWGVATLLSYVLGIWWGWGLNGIWLAMALDENIRAVVFERRWKSRKWEDKSFTRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDH2</accession>
    <name>A0A1Y4DDH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_03465</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56915">
        <property type="protein sequence ID" value="OUO56915"/>
        <property type="gene ID" value="B5F75_03465"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="169"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="304" mass="34315" checksum="E29FF85C38863AE9" modified="2017-08-30" version="1">MSKKNFITIGTFDGVHIGHRCLFNRLEALSVRHLQRPLALYFPYPPKTLLSAHPEMTVLTTPSEKKALLKTLVSNTQALDFAQCRNMEPLDFFENILLRTFQMGGLLIGQDFAFGKDRSGDAAFLREECTRRGIPFETLPFYQVNGEKVSSSLIRKTLALGDIERVNLLLGRPYELTGTVVTGHKLGRRLGFPTANLDTGIYKILPLGVFAVKVRVGRRYYDGFCNIGFRPTVNTIHSSLPLVEVNIFDFHQSIYGRKITVWFAGKLREETKFNGLDALVAQLKKDRQTARALLAQTPPDILQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDL6</accession>
    <name>A0A1Y4DDL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00075</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57214">
        <property type="protein sequence ID" value="OUO57214"/>
        <property type="gene ID" value="B5F75_00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="380" mass="42243" checksum="18CFCFBE1CB7FFF1" modified="2017-08-30" version="1">MTFSWRRARSVALKEYKHILRDPFTLLVTLVLPLVFVGFFGFVIDLDYKHMRVYVRDNDQTSVSRRFLQEAASSGYFDLHPVHGQFQLDQALERNDSPALLVIRPGFGRHIRAGDAENPGEVQLLADGTDNVQASIMGSYMQGVVQKANAVFARDNPALADAAGAGDQIRSRFLFNPELNSRWFIVPALSTIIIGFLAIVLTALTVAKEWENGSMELLLSTPVRPSEIVLGKLVPYFLLTFFDVLVVFVLAIYVFKIPFLGSFLFYMASCWVYITGALALGLVISVVTRQQQAAIQFAFAVGLLPSFIFSGFIFPIENMPAFFQYFTALFPQRWFLLISRTVFLSDAAPATLATALAAIGVFAGAMILLAVHKFKTDVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDP7</accession>
    <name>A0A1Y4DDP7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4401 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57243">
        <property type="protein sequence ID" value="OUO57243"/>
        <property type="gene ID" value="B5F75_00225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025513">
        <property type="entry name" value="DUF4401"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14351">
        <property type="entry name" value="DUF4401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4401" evidence="2">
        <location>
            <begin position="18"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="312" mass="34152" checksum="21C0F360CFAE05E8" modified="2017-08-30" version="1">MPSPAGRCAVTNTETKLPFMVSALVAVGAWLSCLIGILLMGWPSFLRAGVWILLLAVVWTYAAGRTRGVAGAFWTQAALAFSLCGKGMVIFGLVMLWHLSAGQAFWLVLGITLAGYPVFTQKIDRAVMSFASAMALLIWVFQARTVTWPWLESFSVLLFVGAYLLFFVPGEKVRPVAWGLLPACLAAFGLAWMGGNVATLPFNTLFLALCLCGVYAWRAGKDFNVWLAVLMVVLAYLTNVGTVMGGALLALAFSRNRLSLKIAGVAVFALSLVWLYYHMHTTLLVKSFYLWVAGIILLSVYAWQRRRGAYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT4</accession>
    <name>A0A1Y4DDT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56802">
        <property type="protein sequence ID" value="OUO56802"/>
        <property type="gene ID" value="B5F75_02860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="290" mass="32416" checksum="780C24591900F84D" modified="2017-08-30" version="1">MGVACSFLAASASYAQVPASKNAFQIAKALSAQSGRIILPAKPEFSGYLPAFSAAKAIQVNTAQYAPVFTKISPRTVKVNKEKLKEVFLKKQAGKNKKDRMLLVANILLQKQNLLRGYHLPEEYLEGFFMRRIFPYQSAPHYIADQDAERILFRGMLLTPEELIQILKKGFSPDTSKWNAGTDGRAAISLSSSSVEASHYIFQSGSKKNGIGVVFEIRRKPSMLLGADPVLNRTKTIYYSYEDIAPEDIVNVLVWGEYGLENIKDIFAKAKQGNLQPHQRWTGQFGRMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE14</accession>
    <name>A0A1Y4DE14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57286">
        <property type="protein sequence ID" value="OUO57286"/>
        <property type="gene ID" value="B5F75_00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="37"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="296" mass="33065" checksum="3CD9BE4A56D07938" modified="2017-08-30" version="1">MDTAEILKKVRQIEIQTNKLVSETFAGEYLSAFKGQGIEFAEVREYTPGDDVRSIDWNVTARTGVPYIKKYNEERELTLMIACDVSGSQKFGSSSKLKLEAAAELAALFAFSAIQNSDKVGLMLFSDKVELFVPPRKGKKHVLRLIRELVAFEPQDTGTNIGLCLETLSKVIKRQGILILISDFLAPVSSFSKPFKLAARKFDLIPVIVHDKLETRLPPVSACVDVTDPETGEEDFLCLSSGEINTALDDYARTQHLNLQALFNPYKIEPIRVDTALPPADPVIAFFKQRAKKIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE21</accession>
    <name>A0A1Y4DE21_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MlaD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57347">
        <property type="protein sequence ID" value="OUO57347"/>
        <property type="gene ID" value="B5F75_00815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="3">
        <location>
            <begin position="33"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="430" mass="47874" checksum="5545553185966C4B" modified="2017-08-30" version="1">MKPETKLGIFTVLGIVIFGFSLYFLGGLSVTRSYEINVAFEDVSGLPVKAPVKLSGVEVGRVRHIRIEKGQAVVVADIHEGVEIFRDARFSVVMTGIIGTKYLKVEQGTPAAGVLKPGALVRGADEMPMDVMITKTMSSIKEFVDSVNNQGQFGEKLNQTMHEVRQLSANLNQLVAQMRPYLSRSVQNLDVASAKLNDLMAKADSLMNSLEQGEGVIGSLIKDPQMKEDVKDSVKDLKETMGEVKTFVGKMSRFRVYWDYDFFYMPGPALATSDLALEIYPSSGYTFYRAGIANIGNEDDRLDAKDYLEKNQFDVRFGLYNKWATISAGLIRGAGGVALELKPFYDKEFLERFTFTGEFSDWGRDRVINGRLFNKPNLTYGVDFRFNRYFSVGAWARDVLETNDFAVKANISFNDQDISSFFGLAAMAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE41</accession>
    <name>A0A1Y4DE41_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0234 protein B5F75_01065</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0234 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57394">
        <property type="protein sequence ID" value="OUO57394"/>
        <property type="gene ID" value="B5F75_01065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11740">
        <property type="entry name" value="YajQ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00632">
        <property type="entry name" value="UPF0234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007551">
        <property type="entry name" value="DUF520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035571">
        <property type="entry name" value="UPF0234-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035570">
        <property type="entry name" value="UPF0234_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036183">
        <property type="entry name" value="YajQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30476">
        <property type="entry name" value="PTHR30476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04461">
        <property type="entry name" value="DUF520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89963">
        <property type="entry name" value="SSF89963"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="164" mass="18210" checksum="F219C5ED8DDF601A" modified="2017-08-30" version="1">MADYSFDIVSKVDLNVISEAVSAANKEITNRYDFKGTNSSIELNQKDNELKLASSDEYKVNTLRDIIFTRIAKRGIPLKNMLPQKIEAALGGNAKQTVKIQQGIPADKAKEISKAIKDAKLKVSASIQGDQLRVSSKSKDELQNTMALLRGKDFGVELQFTNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE91</accession>
    <name>A0A1Y4DE91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57444">
        <property type="protein sequence ID" value="OUO57444"/>
        <property type="gene ID" value="B5F75_01340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="283" mass="32005" checksum="41320645E3D9DDDB" modified="2017-08-30" version="1">MNILLIVLIVAGIVGLIATTRTRSAQIARMAKTNGCRYEREKNSITTEQTAGRLEFFTQYFHQYQNVCTCTDDFAFIRVADDNIYRDDNPKTKPVKFTIFTAELKKRQFPALKIAPIDSPFAPSQYALMKTNIPQIDSRYRIHAPTPAAALVLTPFIIGLLKTRANIYMELNDNALVYHENAQMPLAEFQQFRFRAIQILHEFENVIVRLDEANPSTTATLVPKAQDEAELRAEAMMKALCTVHNPSSSKASGWRGIWIVALLAVLLGMSLLSWVVLSNWLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB8</accession>
    <name>A0A1Y4DEB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57406">
        <property type="protein sequence ID" value="OUO57406"/>
        <property type="gene ID" value="B5F75_01130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013391287" evidence="1">
        <location>
            <begin position="25"/>
            <end position="1884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1884" mass="211066" checksum="C9734ABD36A44D7C" modified="2017-08-30" version="1">MKILRLPVALLLILQFVAAPPAGAESLPYTLVDRDQYDIFAEDQAEKEEEALTIQDPPDDAQLLKFTNEFWRQAVTSVEGSYKLDNEPEPIPDLTLLNPTLSLPLYGTSIALTGRYVLGFQMAAQKYKKDSNNDINKRNTSTFEMQQEMQLKMQGKILERVFVDIDYDDQREEEKTISVAYRGKPGELVQLAEFGDINLSLPETEFIAYQKQLFGAKMHLQHKNANLYLIGSQTKGSSKQKQFIGSSVSEIISLADTSYLRRTYYDLTFGGNVRPYIDDGGSIRYPVDRTAYDEWRTVMGSISPGTEEIYYYSNDSSTSSDYVPIDRIATDALGSTEYPAKWQLLTRGVDYTVDYASGIITFKRTVTAESVIAVDYRDTRGNQLSNVLGKTGTIKLIKTANDKSIETGPAMVTETANKLELKTYYNIGAQKITQDNGKGNFILQLQDANGQALTSPYYTYPTYIDVDFDSGIFDLAYRINDTGLYGATPTSSKNLTFKIQYESTVKTYFIESGIVIESETVKLNGRTLTRNNDYYIDYTSGFITFYKGDEITENSVIDITYDTTTGSSSNNSVMGGRLDYKLFDKIIMGATMLKESGEKPNTVPQVGNYSKDLLVYGADINGKDIRLAEPLSVDFSAEVAKSKKNQNLFGYAMVDSMNEATEQVAGSRIFRDWIFASNPSGKPAFLNSIHWDTQDLPSLEINPHSIANYNDKQQVLVLNYDFTLPATTIDQTTGQPFLNEEGRDEVSIVYPLSQSGMDLSSKTSFELTMLGEENGPQVNFAFGNISEYSDSSNGMDTQCGTNVPKTEDIYCRNTLAPNEDIGWLFTNPDGTEERYNPFVNNVYNPESQPNGRIDTQDLNGNGAYDAESMPAQGNFGFAGASIDGMVNNTASNTAWTTYTMPLLLSTEEKEQWTAVRHLRITLKLTDEMKRAGKLKGQIKIANVSLSGTAWNAQNETDPDVFSVAGINNVDDTNYEPIFADTTGDGLTVFNYLYGSVNNYKQATGSANALDQALNIKFNTIGLSPVRDDSTENNPAGERYANRNFSSMDFTQHREFRFLLHGAMEQGGARPLNQPGTEFFLKVGTENNFDKIIVPTDFRGWRLISLRMVDTDMDGVPDSFENISDPSYNVRVVHHRGPGGLLNFREVSLMFTGVQPESRYTYTFTQQDNTQTLFARGILQPGLALYGDANFTVSAGTVQTVSTQADGSYAVTLENGKSYTAVLDQVSALGSQGEVWLNVIHLAESITLEGTAYKGDVVVNLDGWGSAGAKYKYQDSNFETPLAVSKNQEVTQEEYFLKVDKIKEFPMQANLTRSSTVTPLVTDTTDYNTISLLDKGKVDRQSAVVRGDFKKDNFPQIGLEYTTDQVEYDAMKRKDDARTYGATLTHSAGTFKNITAGYHITDSSINYDRTRHLESDNYYNTDENTQKMNMKVTYQPTNNFNFTPSYSLSKSKEDRTTYQETSAQNISYPKAMSQNTGFNSTWKITKWLAPSVSYNISTVESNNLTAKTLNAAGQQVTVGVGEVKTINRNADGGISLTLNGNEILPNSKLFNTFVISSSYRIQDADSWYDVDSDYDSRKDLWIRSSLKDVGEYGYRKSLTLRDTFTSTQRWSPLSQYNLEGAAAPLKTISLINNFTRTLQTNDQTGTLYDSTSLTLPDMTFSISDLEKFFYGGRWFSSSNLKLRYSWVEQNTPGTDEQYTTQYGGDLRFMLFNYFDTVLNYTRKTSDKTDLRAGTSLERIEDNDISAQTSFYIGSMRVTPKLLHTSHEKWLVAGQISESSTETTPSLNLRWDFNLPRGFKLPFINKMYNATNRVIWNTTFSYTDKRSPVEVTENYKKFDFSTSLDYELSQNLRFTVGGGFTLLNHAYVETEDYTAYNVAANVTVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG2</accession>
    <name>A0A1Y4DEG2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">B5F75_01810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57534">
        <property type="protein sequence ID" value="OUO57534"/>
        <property type="gene ID" value="B5F75_01810"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="1-deoxy-D-xylulose 5-phosphate binding" evidence="2">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="240" mass="26097" checksum="E9FDBF9943933A4E" modified="2017-08-30" version="1">MQMSLKLGVNIDHIATLRQARREPFPDPVDAAAVCLATGADYIVVHLRKDQRHINEKDVALLCKTFPGKIHLECSYTPELEKAALKYKPFSVCIVPEEPGEVTTTGGLKFSPKVNKRLLEMIENLHKKHILVSLFISPDAASVRTAAKLGADIVELCTRDYSEAASAKQARKCLQDLALSTLLAKELGLEVHAGHGLDYHNVLAVADIGGMACMNIGFAIITRSLFAGLPTAVNEMKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ1</accession>
    <name>A0A1Y4DEJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57052">
        <property type="protein sequence ID" value="OUO57052"/>
        <property type="gene ID" value="B5F75_04180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="521" mass="53559" checksum="AF624D76BF71F137" modified="2017-08-30" version="1">MNIFKWLGKSGKIALSAAQAVGLSAVVGVAGIAAWQYLDTPSDNTAFNLGGQYNPGEVVYVAGASGGSYGANGEVQSSFLATPSKAIEMTEKFALAQKRAEEYEDSVSDEALAPSNPQAYQMGGTEGLGMGANRANEEELKNNPMAFAKQSLSGVSDAIAQAQAQAQAQQAAAAGGQAQGAAPAGTLASASRDWGSSAATKGGSGGGGNSFNSSFVVQDSTKNGGKGAGAAGQNQTPEQIMKNFQSQVASAQENARLRARASFGEDEMLASDKNLKALDGRSSREKSDLAFIRKRSADAAANRNRAANEASRAWLDGTKVSGGMSIISGESVTTGQGQGSKDFNDATEAQLRGIQTYATTPLEQKALERKKARDNIRMWMWIAIPTALAAMVAIPAAIASAGWIFGAGWIFAAAIAAVALIPVLSLLITSAKYAKEYSGSSLSTWGITIGSILTAGIGAAFIPGVGFAVKWATWAQLLLGGGAAGLGALGAWWVNSGTKDATLDSENPDLDMNGQNDEQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL1</accession>
    <name>A0A1Y4DEL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylosuccinate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57506">
        <property type="protein sequence ID" value="OUO57506"/>
        <property type="gene ID" value="B5F75_01665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006188">
        <property type="term" value="P:IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="2">
        <location>
            <begin position="91"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="3">
        <location>
            <begin position="336"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="462" mass="51375" checksum="4F4EEABC409BA830" modified="2017-08-30" version="1">MNIPALCPLDGRYSGRLGALRSVMSEAAFTAYRVRVECAWFEILSELKLFKPLTKEERGLLAQACELSAADLDHIRALEFDGYLHIPPTRHDVKAVEYFLRLRLGKTSLKDRLQWLHFALTSEDVNSAAYALLLTQGVEKALLPALENLQKELSKLARKEARSVLLARTHGQPAVPTTFGKEMRVFANRLARQIAQLKRQEITFKFGGAVGNFNAHYAAFPQVRWPRAAAKMAAVLNRGHKMKISLTPVSTQVDPRDSYAELFDNLRRADVALLDLCRDMWQYISAGLVHQKTAAGEVGSSTMPQKVNPIDFENAEGNLQLADALFGLFSCKLPVSRLQRDLSDSTVLRNMAVAFGYALVAYQSVLKGLGKISFDRAAARQELCAHPEVLAEAVQTLLRAAGYPHAYETLRDFTRGRAVTASLLQQFIAGLPVDAATRSKLQALCPENYLGRARELAEEKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL7</accession>
    <name>A0A1Y4DEL7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57345">
        <property type="protein sequence ID" value="OUO57345"/>
        <property type="gene ID" value="B5F75_00805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="2">
        <location>
            <begin position="250"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="315" mass="35013" checksum="32E3C00B806C98CF" modified="2017-08-30" version="1">MPIWIFRISTLVAFPFLTYNFIDKEWMSLLAGLLCGALVVGGEVLFKRLRLIKIMIACSGFLLGYMLYVFFDYGMIHFAEADVMNFWMTYGRDIEIGLIIFGVIASLIKSRDLEGLSYTGHHLKVADVTALMDGRIVDLCEINFLSGIIVLPVFVLDELNKMAASKDPLERAKGRRGLDVAARLRELSEIAVRVTSKTPKADTMEERVVKLAKSLDAEVVTLDFNVNKIAALHDVIALNIADLATALKPVVLPGESMSLFIMKDGKEKEQGIGYLDDGTMVVVEDGRKYIGKRAEVSVYSILQTSSGRMIFAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM8</accession>
    <name>A0A1Y4DEM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56179">
        <property type="protein sequence ID" value="OUO56179"/>
        <property type="gene ID" value="B5F75_06065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011988711" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="9"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="160" mass="17704" checksum="9597CA87807D0013" modified="2017-08-30" version="1">MKKLLVLTVAALLAAACMKLPELPTMGLVQIPIAGEEEALWTSTDYEGKPVLMMYMGSWCPYCKMSMPALNTVAEKYAGKAEVVGVFLDADPETVLKVAKEHGLNTKVLYNGQGPADVMKVTGLPHAILFDRKHRVVRIWEGFSPTLAQEFDEHLQRLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEP4</accession>
    <name>A0A1Y4DEP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome partitioning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57643">
        <property type="protein sequence ID" value="OUO57643"/>
        <property type="gene ID" value="B5F75_02385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="277" mass="30369" checksum="33CAF622491BDE04" modified="2017-08-30" version="1">MGEIVVVANQKGGVGKTTTSINLSYALACLNQQVLLVDFDPQGNAGSGLGVTVADGEKSVYHLLTKTAPFEQVVRQTSSEMLDVLPACKDLAGAEVELVNVRGRENMLKDALAPFRGMYDYIIIDCPPSLGLLTLNAMMAADSVITPVQCEYYAMEGLAHFMSTVSKIKQFLHPKLKMDGGVLTMYDARMNLSKQVFAEVSRFFGDQVYKTPIPRNIRLAEAPSFGQSIFDYDPACRGANAYIQLAIEFLTRRGADPTQYKDFKMTGEMPLNYDFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU4</accession>
    <name>A0A1Y4DEU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57617">
        <property type="protein sequence ID" value="OUO57617"/>
        <property type="gene ID" value="B5F75_02250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="320" mass="35995" checksum="72DFAB1E03DFB4DA" modified="2017-08-30" version="1">MPMMKTSADSFIRGNPAFGRTVRDFVQRNGLSLLKKNNSFYCGCLKRYNIYMQFIDSHAHLNDPAFDADRTELITQKLPQAGIALSVEIGCSPEEWQPALELSSQHPSLIRAVLGVHPEYACKMNDAAWKQLAALLPDERNVAVGEIGLDYTCLEFTDKEKQQEAFARMLALANQTQKPLVLHIRREGDDYAAYEDSFRLLKHQWNGSSSTGYPGVLHCFCARYEEAKKALDLGLLLGINGCFTYKKNEYIREAVKKAGADKIILETDCPYLSPQGKRGQRNDPSNVPLIAQFTADYLNMPLEELAEMTTRQAKALYGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW7</accession>
    <name>A0A1Y4DEW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57455">
        <property type="protein sequence ID" value="OUO57455"/>
        <property type="gene ID" value="B5F75_01395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="192" mass="21177" checksum="989BC76CECE404F8" modified="2017-08-30" version="1">MSKTSYCLIAIMLAALLYMGAVRGYQFYERRAAEKAAQDAVSGNAFTFQNVPVSLAAPRPEPVSRPVAFDPAQTAIFLESAPLSFDLQQQQAQETIESILMDYAQDPNIQKFNQELADATEGEADNLADLSGEKMLKILQENPQVGKVVQESMQNPEFAKTIEQIFTNPQFIESVKQLQGNMSAAPQPKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY5</accession>
    <name>A0A1Y4DEY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">B5F75_02465</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57657">
        <property type="protein sequence ID" value="OUO57657"/>
        <property type="gene ID" value="B5F75_02465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="9"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="76" mass="7512" checksum="C1604A6158536A15" modified="2017-08-30" version="1">MELVALKYIAAGLGAGLVVIGAGLGLGKIGNAALEGIARQPEAGADLRSTMIVIAALLEGAAMLGLVICLLTLVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEZ6</accession>
    <name>A0A1Y4DEZ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57667">
        <property type="protein sequence ID" value="OUO57667"/>
        <property type="gene ID" value="B5F75_02515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="377" mass="41178" checksum="FEEB9A71BF490D9C" modified="2017-08-30" version="1">MKTFLKIVLLLAVLAGVYVFVFYKTPQQREFEQTLSAAQAGDMQAAFKVAGLYAAGQGVKTPDGAQAAEWYRKAAADGNVEAAWKLAQLYIEGKVLPKNLEEAAVYLQLAAREGNAQAQTELGRFYEQGLGGLPSSRGEALNWYLQAGQQGDAQAQERAQDVQLEDPQLYEEVTRFQALLASAKTGDSQAQLEVGQMLREGYVIAQNNEEAARWFTQAWQEGEKLPQAAYELSRLYQNGEGVEKNEAKAMELLGAAAQAKNPDAQYQMGTLAYGANPPKYEDAFAWFSNAAAGGQAQGQYMTGFMLMQGQGTPKSVELAIQFFRKAAEQNHTAAQYVLGQIYWKGLGVPANKKEGEQWLRRAADSGNEAAKALLTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF80</accession>
    <name>A0A1Y4DF80_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gpsA</name>
        <name evidence="15" type="ORF">B5F75_00545</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 11">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57302">
        <property type="protein sequence ID" value="OUO57302"/>
        <property type="gene ID" value="B5F75_00545"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0520">NAD</keyword>
    <keyword evidence="3 7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="13">
        <location>
            <begin position="5"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="14">
        <location>
            <begin position="183"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="334" mass="35936" checksum="D520E8801F1461AA" modified="2017-08-30" version="1">MKINKITVLGAGIWGSVIAQHLAKKGYNVALWEYNEHLLNVLKTMGRHPNIPNFKLHDNIRLTGDVAEAVQDTDLIIFVISSKAIRSFCRKQLKPLLNGRAVPVVSASKGIEDKTFKTICELIEEELPQLKDKALAFSGPSFALEVAQDVPTKIMLAGKDPALVDEIRDVMSGDPIIVVPASDRRGVEYGGGIKNVLAIGCGVIDGIGDGANSKAALITQAMQEMNDIIVSQGGQPGTVYSLAGFGDAILTGMSAISRNRRLGEKLGSGLSLEEAKKEVGTIAEGVNSVQSVYDIARKNNLKTPILDAIWQIVCQGKKPWVLLHAMGFTNRGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFA0</accession>
    <name>A0A1Y4DFA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplW</name>
        <name evidence="10" type="ORF">B5F75_06965</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56349">
        <property type="protein sequence ID" value="OUO56349"/>
        <property type="gene ID" value="B5F75_06965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="11146" checksum="7109F3E2A220339B" modified="2017-08-30" version="1">MSRTYEILKKPLLTEKSLIERDNHNRYGFVVSKDASKGEIKTAVEKIFNVTVTKINTISVTGKTHRMGRFEGKRPDYKKAFVTLKEGDKIEVVEAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFI3</accession>
    <name>A0A1Y4DFI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal peptide peptidase SppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_02665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57695">
        <property type="protein sequence ID" value="OUO57695"/>
        <property type="gene ID" value="B5F75_02665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="4">
        <location>
            <begin position="182"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="379" mass="40842" checksum="EA11268EEE483520" modified="2017-08-30" version="1">MPENENEGLSASTDMSLPKEQWEQKLLENEKTAFLTTDSDKKEETPKDPKPAKRLSGRGAWSFLLLACFAVSAVCGVYLTVRPVPACPSAKEAKPSAEEVLGASLSARNKKGNVAWIKVRGVIAQDNSTSPFSRPKGASEIAKKIREAGEDKNVKAIVLDINSPGGTVASVQDIYSEILRAKENKKVVALFRDVAASGGFYIAMAADKIVAEPGTITGSVGVIMQTGNVEGLFEKIGVKVTPITSGKYKDMGSAYRPMTDAEKAILQDMVDDTYGQFLAAVKAGRPNVKPEDMTEYTDGRIFTGQRAFNLGFIDKLGGEEEALALAGELAGIKDPQIITQRPESLRELIFSFGSSVESQTLTQQLQSIATPSVSYLWVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFN0</accession>
    <name>A0A1Y4DFN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56499">
        <property type="protein sequence ID" value="OUO56499"/>
        <property type="gene ID" value="B5F75_04710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012328001" evidence="1">
        <location>
            <begin position="20"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="398" mass="43058" checksum="DFAEE22A4162D27B" modified="2017-08-30" version="1">MKKFFLLTTVLLFGNLCRAESLQFVTTLASPVGTFASLETADPTATVSAPLVNFCNRRISTGLVTLSGANAYIYTMHLQNGATLGGTVPEYRVSGTMQVASGATLEGGRLMANEVTLEDAVMAKSNVTDTLYLDSSEVLGAKADALSIPGQVETSGTGSKENMEWNNSYTCDYKISEAEDIDETTYMVRYNPDTGRFEHPSGLDSGDTCDSNPLVKYTGTPSQTCLDIWLDGSGTTSSMLDMSFGTIHLYQVGDGCDPYTMPCGSYQRVIFPCKANIPYGGGADIRYALSSSNSSLSQSQRWKYYVPKSSQIAKFFGGLKSAYNSWLNNGDWDLGHPYTFNVCLSDAEATFQGKGVHYTISYGRTSFKAQKHYPEGSSGGNATCVSDNKYSSYLLKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFU8</accession>
    <name>A0A1Y4DFU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56549">
        <property type="protein sequence ID" value="OUO56549"/>
        <property type="gene ID" value="B5F75_04975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="522" mass="57795" checksum="919F04180F04A6AD" modified="2017-08-30" version="1">MLLLLLASAPLAGASVFTSQDGAFTLDMPAGWVQLKNPPQDSVLSIQKGSSRIDIKTVDCSTETCIEQKVTNDLADVKSKKMQVIGNSYTGEEIKRIEFSTGDPFFYISFFTPKNDFGAGYFLIDKKGYSILAKDLTYAETDLVFSFISPVKKETPQPLEMDLDSPRAYDIAALPAVQEEALSMPLAAPAEAQSAPAAAPQAQPTAGTLKKIISKLRVRTLLSKNMPPYIRNMGRGFDGLIGLLVLFILLLAGAGCLRLLIRRPHTLPPANPNSLYPIKFKRLYGTPSLIFRAKDNQGNVLTSLSARWDSLFLFCGLALIVLTLLVLAGAGLGENSGLLPLSSFAYSTIYSACSLLIPLGAVIFFCGVVWSQLVLREITLFDRKGKKAAIVLQKGFGLSHERYEIYFARSKDVLVVTRKRFALRRTWRMFTREGNALATLTETSAWKAVLRKICGHLWGFLRADYTIEGQMDSKGVIQNAHAPFDRFICNIDKPQALNARDLLVISLLINIRDKDKWYPWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG09</accession>
    <name>A0A1Y4DG09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="6" type="ORF">B5F75_02065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57582">
        <property type="protein sequence ID" value="OUO57582"/>
        <property type="gene ID" value="B5F75_02065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="372" mass="42310" checksum="8071B4E1B572E7A4" modified="2017-08-30" version="1">MNNIEFKDVEQKLEELAARVAKIESIDDIPGKQKELAALQQQSADPSFWNDTKKAKEVSRQIDFLKNSIDTFRSLGKKIEDDRTWFDLCKEMQDEKELLALNASLQETEKQVAQKEGEIRLSEPNDKLNAILTIHAGAGGTESCDWAQMLARMYTRWAEQHGFKFSVLDTQPGDEAGIKTLSAMVEGPYAYGYLKGENGVHRLVRVSPFDANARRHTSFASCDVLPDIDENINIEIPEKDIQLETSRAGGHGGQNVNKVESAVRLLHIPTGIVVSCRIERSQLQNRQTAMKMLKARLYEMEMDKKRSEAEKRYGQKGEIAWGHQIRSYVFMPYQLVKDLRSGYETSQINAVMDGDLDPFIFAFLNYEAEHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG29</accession>
    <name>A0A1Y4DG29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57602">
        <property type="protein sequence ID" value="OUO57602"/>
        <property type="gene ID" value="B5F75_02175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036192">
        <property type="entry name" value="Cell_div_ZapA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102829">
        <property type="entry name" value="SSF102829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="110" mass="12472" checksum="68A4048217907D89" modified="2017-08-30" version="1">MHNPRQKSYNTNMAKDIVQVEIKRIPLDIEASELGMVELTDLAASVEKYMLQLQEEGEIDTLKQALLAALHFAAQAYLQSQNEGGKRKEEESRVDDLIVKLKSSLDNTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGJ8</accession>
    <name>A0A1Y4DGJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin-dependent thymidylate synthase</fullName>
            <shortName evidence="1">FDTS</shortName>
            <ecNumber evidence="1">2.1.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">FAD-dependent thymidylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Thymidylate synthase ThyX</fullName>
            <shortName evidence="1">TS</shortName>
            <shortName evidence="1">TSase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thyX</name>
        <name evidence="2" type="ORF">B5F75_07115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP + H(+) + NADPH = (6S)-5,6,7,8-tetrahydrofolate + dTMP + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:29043"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.148"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="1">Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidylate synthase ThyX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.148" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56058">
        <property type="protein sequence ID" value="OUO56058"/>
        <property type="gene ID" value="B5F75_07115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01408">
        <property type="entry name" value="ThyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02170">
        <property type="entry name" value="thyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Involved in ionization of N3 of dUMP, leading to its activation" evidence="1">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <note>ligand shared between neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="73"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="76"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="84"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <note>ligand shared between neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <note>ligand shared between neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="223" mass="25876" checksum="58E5460F8B478E48" modified="2017-08-30" version="1">MNVLDKGFVRLVDFMGGDDRAVQAARVSFGAVSKGPEQDKRLIKYLMEHAHHTPFEHCYFQFHICCPIYVARQWMRHRWGSYNEVSARYTEVKDEFYIPSEFRKQDTKNKQGSVADSALDNAALRKIYEDSVEASYAAYHKLLEAGVAREMARGVLPVCQYTQFYWSVNARSLFNFLCLRTDKHAQKEIRVYADEIAKIVAEKMPWSWEAFEALNKQLPLGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH86</accession>
    <name>A0A1Y4DH86_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56288">
        <property type="protein sequence ID" value="OUO56288"/>
        <property type="gene ID" value="B5F75_06635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="143" mass="16303" checksum="82AFC9568594636E" modified="2017-08-30" version="1">MKYYQMALDLRRQQEVYYLANGAYAENLSDLDVDYSHVCQIRKDAPWMLECPFAEISNVATTFEGENQGSAQIKFFSRWQTPSSSATPEEMPSEKDSVQDFFLLLWYAHASVPNGVLCVPYTPLGKSVCNNIKSLNAEDLWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH94</accession>
    <name>A0A1Y4DH94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56298">
        <property type="protein sequence ID" value="OUO56298"/>
        <property type="gene ID" value="B5F75_06695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011894">
        <property type="entry name" value="PorC_KorC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02175">
        <property type="entry name" value="PorC_KorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="11"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="178" mass="18992" checksum="AF6F3F35C8328FD0" modified="2017-08-30" version="1">MYQGIRIAGFGGQGVISAGILLAQAGVEDKKNASWLPSYGPEMRGGTANCSVVISDGEVYTPIVSAPDTVIIMNEPSLPKFEPLLKKGGLMIINSSLINSRPTRTDITVVCVPCNKIAEELGMDRIANLVALGAFIKKTGAVTLTSVEHAMKKVYKRAKPEMLELNKKALQAGYDAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHA9</accession>
    <name>A0A1Y4DHA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56318">
        <property type="protein sequence ID" value="OUO56318"/>
        <property type="gene ID" value="B5F75_06805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="47"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="484" mass="54575" checksum="0B7BC066DFDF9EE6" modified="2017-08-30" version="1">MSKNLEGQPTVEVLVNTSFEETRIAILEDERVNELIWERRGALNIVGNIYKGVVENVLPGISSAFLNIGYEKNAYLYISDVLGGDKKNIDKVLHKGQEVMVQVVKDAISTKGMKVTMDVTLPGRYLVLTPHQSFVGVSKNIEDSEARHKLNEIMQELAAKHLDGMGCIVRTEAEEATKEELEREVKYLYRQWQSIVKKFEAARGPKLLHEDMDAVLQVARDVLSENAKVYLLDSKKDYERVLDFVEKNSPDLADRVKLYKGKTPIFEAYDIETEIDNLRKTKLPLPNGGSIIIQEAESLCAIDVNTGKFTGNKSQEETVTQTNIEAANEIAHQLRLRNIGGIIVIDFIDMRKASSRHRVVEALAQAVHGDRAKIRILPITRLGLVEMTRERKRASTGSFISEECPQCHGSGRVLSAESMRIKIQREIYDLTSGRPGGNLRVVLHPVLAEAIKARQEDIEQNIHRTLKIQADPQLAWEDYKIVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHS3</accession>
    <name>A0A1Y4DHS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56488">
        <property type="protein sequence ID" value="OUO56488"/>
        <property type="gene ID" value="B5F75_04655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009574">
        <property type="entry name" value="DUF1189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06691">
        <property type="entry name" value="DUF1189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="246" mass="28168" checksum="697005BCE8C1FA8F" modified="2017-08-30" version="1">MLWAHIKTIFSFRFYHILAFSSRRFMVGFGIYLFFLSTVVFYFFSSGYIKDNLPLLLKNFPQVTFEKGVLTQPQQPVSASVPQSDFKIVFDASLKTPPSSEELLKDNILCLVTGNKIYVPSSGGIQQTELPKTFSFVTSQENLAKQKDVLESSLRAVTLFTSLFAIPLVMLFSFCTAGAVGLFFKLMRRSYVPRTAVLKWAFFMMGPLSALWYVRLWINIPLFTFAQVILCIIYMQQIFNTLPEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI24</accession>
    <name>A0A1Y4DI24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56598">
        <property type="protein sequence ID" value="OUO56598"/>
        <property type="gene ID" value="B5F75_05245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="34517" checksum="4036A69866EF5A23" modified="2017-08-30" version="1">MPSVKVSVIVPVYNQQAYLTQCLESLQNQTLREIEILCVNDGSTDESWSLMQEFAARDSRFVLLNQPNQGTGRARNAALARARGEYVGFMDGDDFVDADYFEKLYQKAKEDRADVCCALDRREINGIQVQEVSTPVFAEADKFKKQLVFTAAQVWSKLFLRAFVQQYPLQNAVSRREQEIAFSIPAVLLARRISWVAGAYYNYRIQSASACRKPITRQDCEELPRIYAAMLALPLAEPQRRLVMARLKTNMQAYLRQVSFSRRIVLFRSALQTIPSFGWDGKYAGAYFWAKLWAGKGATGENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI44</accession>
    <name>A0A1Y4DI44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56618">
        <property type="protein sequence ID" value="OUO56618"/>
        <property type="gene ID" value="B5F75_05350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="21094" checksum="5D145E48E1C3B430" modified="2017-08-30" version="1">MATIYQKSFPGTKNAGFTLIELLVVVLIIGILAAVAVPQYQKAVEKSRISALFPIARAVETAQKAYYMATGSFSNEMSNLDISVPLPTAPAAPPCSLAYQSSDSARQDTQTVVALNNRSSAKSYFVAAARLTGPYKCSGIKIPLKDVSVLKEGKTYCYEHIAHFTGEAGSFCQKMMNGTYVTSFDSCRFYEIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIB0</accession>
    <name>A0A1Y4DIB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplJ</name>
        <name evidence="6" type="ORF">B5F75_07185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56050">
        <property type="protein sequence ID" value="OUO56050"/>
        <property type="gene ID" value="B5F75_07185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="19055" checksum="C465D3F29D9E43A1" modified="2017-08-30" version="1">MNLTKDQKKQKSQDLASEITASGTLFFTAYQGLKFVDMAELRAQLAPTGAKFRVERNAIVDHAIRQAKIEGADEKLFQGPTAIAVGGDIAAVAKALVDFQKKFAALKLRACYSDGVWYSEEQVKQLATIGTKEENLSKLAGALYNAVAQSAQVLQAPIRDFAYVIKAVEDKQNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIE3</accession>
    <name>A0A1Y4DIE3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ORF">B5F75_01260</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57429">
        <property type="protein sequence ID" value="OUO57429"/>
        <property type="gene ID" value="B5F75_01260"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="42"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="266" mass="28576" checksum="D333042300729EFB" modified="2017-08-30" version="1">MKKQPIGVFDSGLGGLTILNALHRELPHEDLIYFGDTANVPYGSKSKAAVTKFSLAIARFLESLGVKLIVVACNTASAQALAELRRRISVPVMGVIEPGAERAAQTSRNGRIAVLGTEGTVKSNAYPKAILKRSPQARIIQQACPLFVPLVEENWGKKPAAELIAREYMARVQKSGADTVILGCTHYPILKPVLRKILGKHVTLVDSADTLAQAARAFLTARGQAAAQGKGCVRLYASDDPARFKRLAGYLLPGKIGAVRLKKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIM0</accession>
    <name>A0A1Y4DIM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56778">
        <property type="protein sequence ID" value="OUO56778"/>
        <property type="gene ID" value="B5F75_02740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012463877" evidence="1">
        <location>
            <begin position="21"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="323" mass="35903" checksum="F5BAD9DB675FE95A" modified="2017-08-30" version="1">MKKTFALVCLSLLGVTAAFAAGKPASKADVSAAVNAKVANALQNNNGAIKNNLRVDFRITEYVTRYVEDGVVFPSEDEPQNGRIQKGPYEADLACKAYALDSNWLILSGTCMRYSPDPVQVYEPTYYERDGREIDSDFSVGNYSIPAKNYAYNDDIMLLWTGDANTAKFLSELPKVNVLAVSSPNKLFALSDVNTFKINTARLGTNAIRERKLKTNSIKGNMLQLEEGATDLSGTATDPLFLVTPSGREFLAGYNDGILGYALQITFNDIVHTFDGRTSKDYFTLSEKDLNFIKKTVLEQRPGDWKRIKNRLFLDQTATPYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIU1</accession>
    <name>A0A1Y4DIU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="10" type="ORF">B5F75_03155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56858">
        <property type="protein sequence ID" value="OUO56858"/>
        <property type="gene ID" value="B5F75_03155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="9">
        <location>
            <begin position="213"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="223"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="242"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="449" mass="49019" checksum="7DDD7A1DF1B37072" modified="2017-08-30" version="1">MQHTICALATGAGGAVALVRLSGPEVCRLLAVLTRRPQPPEPRKQALRTIYDGDAVLDKALVTYFQAPHSFTGEDVAEFAVHASPYIKGRLLELLCQNGAVMAKRGEFSQRAFLNGKMDLVEAQGLCDLIASGNKAAHKLAMDSLDGKLSARLEEIKKRLSELLAQIEVRLDDVDEEMTPLSDDFVRGELSAVLGHIKALADTFSVGKYIKDGLKTAIVGAPNSGKSSLLNALVGFDRAIVSDQSGTTRDTVEETLEINGQKIILTDTAGIREHALDPAEKEGMRRSHRAMEAADLILFVLDASRPLTPEEQELWQDIRRQNKRTVLVWNKSDLSASRPTLQAQEQYPSVSVSCKTGDGLNALKDLITADVTEAQTADGLMISNLRHYEALLRAQTELESALIRLESHAGGEIYAEHLRRALNDLQDLIGEVTPDDVLGIIFSKFCMGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIV4</accession>
    <name>A0A1Y4DIV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TolB_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_06425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56250">
        <property type="protein sequence ID" value="OUO56250"/>
        <property type="gene ID" value="B5F75_06425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007195">
        <property type="entry name" value="TolB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04052">
        <property type="entry name" value="TolB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010990262" description="TolB_N domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="TolB_N" evidence="5">
        <location>
            <begin position="30"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="431" mass="47823" checksum="C1A4DED451218974" modified="2017-08-30" version="1">MKKIFSFFTVLAVVLTAVSAFAARPQTDVYIGITSVGDRKLPAIAMPPFRFADNKAQAAAVQVHDVMRADLLFARYFDVTEQGPAFDPQNVSQTLSQWAQLRASYLLAGDISYAAPYYTIKIYVYDLSTRTAVFAKAFKGTESSLRRLAHIASDQIVSALTGKRGIADTKIAFANNATRHKEIYVVDYDGENLQKLTNDKSISILPRWSKDGKIFYTTYKYKNPDIFAIDLRAGKIAPIIIRGGLSLIGGVSPDGKALAFTSSGGTNPSIYIYNLETHEKRRITNKASVDGSPSYSPDGKYITFVSNRAGNPQIYVMELATGDTRPLTKTFNWSDSPQWSPTGEWIVFTGRESPYHPMDIFLVDLTGTQIRRLTTDAGSNEDPTWSPDGRFIAFTTTRNGKRQLYMMDMDGSAPHLLADLKGDSFTPHWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIY5</accession>
    <name>A0A1Y4DIY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="2">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_06595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56280">
        <property type="protein sequence ID" value="OUO56280"/>
        <property type="gene ID" value="B5F75_06595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="384" mass="43658" checksum="A266F12E5044A724" modified="2017-08-30" version="1">MSTITPITKNILFVAGDVSGDIHAAGLIEAIKEADPDVRITSVGGKRMQAVSDEFLYDLASKGASGFIEPLKKMPLWIRLMNQIREYMETQNPVALVVVDFYGFNHQILGMAKHRHIPAYYYVTPQVWASRQYRAKRLAELTRKMFTIYPFEPEFHKKFGGNAVFLGNPLLDQLPLPTEKDYHIPDHKNHAWKLGMLPGSRMGEIKRLTPVFYQAYKEVLKEFPNTQAYMFLLPDADEKVFLDLIGEKPHANFHLVKDLHYELRSQMDFLLACSGTATLENALLGIPMVVAYKLFWPTYQIAKRVIKVPYISLVNLLSKKPLVKELIQYDATPRALAAETMAMFQNPAKLAQMRKELLKLRASLGEPGVAKRAAAEILNDLKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ32</accession>
    <name>A0A1Y4DJ32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="10" type="ORF">B5F75_03685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56958">
        <property type="protein sequence ID" value="OUO56958"/>
        <property type="gene ID" value="B5F75_03685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="434"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="471" mass="51369" checksum="B16121032CC0A620" modified="2017-08-30" version="1">MSNKLAVKWGLIIAILLGSLYLIYPNYKWYSKPLAEREKLDTLGERPKRMLNLGLDLRGGSSLLLELDVSKLSAKEPLNEAMARAVEIIRNRIDQYGLAETQITRQGDKWIMVQLPGVSNPQRAEELIGKTAMLEFRIVKNDTSAAQKALEKVESTEKPFDDNGVLIPEIAKLVPEGYQIMRNKEGGYSVVTDTAPVTGADLENARVVMMGENGYPEVAFTFNAEGSRKFGQLTGSNIGKQLAIVLDNTVQSAPVVQSRITKDGRISGTFTPEEARSLSIVLKAGALPAPVKVIEKKTIGPTLGEDSIKSGLSASFYALVIILLFMLVYYKAAGFIADIALLLNFVFTVAIMSYFSATLTLPGIAGMILSLAMAIDANVLIIERMREEKLLGKPVYEIINLGYDKAWSAIFDSNITTIIVGACLLQFGTGPVKGFAVTLIIGLTVSLFTAVFITRAIYELILTSNTKEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ75</accession>
    <name>A0A1Y4DJ75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_03885</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56998">
        <property type="protein sequence ID" value="OUO56998"/>
        <property type="gene ID" value="B5F75_03885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="121"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="228"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="411" mass="45288" checksum="114F6817C4B0225A" modified="2017-08-30" version="1">MDYAINEMEQEVLNATRELAQKKLKPLRAEMDAKEQFSNQMLEEYRKSGMMGLWLPEEYGGLGGGITCLAMAFEELSRVCAGLALTPGTTALGAIPMFLAATKEQRERWCPDVASGKKLWAFALTEPEAGSDATALKTTALKDGDFYVVNGTKHFISTGKEADFYTVAVNTNPSRGARGISLLVIEKGTPGFSFGKKEEKMGIRTNPTYELIFENVRVPKENLLGSEGRGLLYLQETLDYSRPGVAAQAVGIAQGALDETIPYLRTRKQFGQPIITFQALGHKIAELAAKTEAGRALVYSLTHRMDTEYLPAVKAALAEGTSVHDELKKLKGQRWTKYSAEAKLFCSNVAMEVADECVTLCGGVAYMRDFPLEKYMRDAKITQIYEGTVHIQKNEIITALIKEYAAKGDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJG0</accession>
    <name>A0A1Y4DJG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="3 13">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">B5F75_04510</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Adenine glycosylase active on G-A mispairs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="3 13"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56460">
        <property type="protein sequence ID" value="OUO56460"/>
        <property type="gene ID" value="B5F75_04510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12 13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="14">
        <location>
            <begin position="36"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO56460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="344" mass="39172" checksum="8595B6CB6B0A9131" modified="2017-08-30" version="1">MKSFASILLDWYDQHKRDLPWRHTRDPYLIWLSEIILQQTRVAQGMEYYLRFAKRFPTPLSLAEASEDEVLKYWQGLGYYSRARNLHAAAKSMAGVFPRSYEGVRALKGVGDYTAAAICSIAYQMPYAVVDGNVYRVLARVFGISIAIDSPEGKKVFMQKAQQLLDGKRPGDYNQAIMDFGAMVCTPVSPQCDACPLAKRCKARQEKRVEELPVKMQKTKISSRYFHYIYVRQGNNTWLHKRGPGDVWQNLYEPPLVESQTPEENWLAGAAYKRLFGRRKAMLKVPPVKHVLSHRVIYADLSEVDLPSSCPVAEGFLCVSAKEIPQYAVSRLVQKLLEKAKVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJW0</accession>
    <name>A0A1Y4DJW0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56620">
        <property type="protein sequence ID" value="OUO56620"/>
        <property type="gene ID" value="B5F75_05360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="17356" checksum="AFE40E762296CD16" modified="2017-08-30" version="1">MGKLIKRYFALNIWVKIIFFFCLFGAFVNFFLVWRDIAANGILLRLHAGFLVLYVSQVVFILLHERYVSVLAALQGLLALLTNADFTFVPLLRGVGQFYYLANPVPSVEAMTVYKYVFVSAAFTLQLLSAYALFSLLPKYEPKKKEPSEPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK42</accession>
    <name>A0A1Y4DK42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">B5F75_00525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57298">
        <property type="protein sequence ID" value="OUO57298"/>
        <property type="gene ID" value="B5F75_00525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="161"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="317" mass="35398" checksum="1448904E17FEAAD6" modified="2017-08-30" version="1">MKPIVLCGPTASGKTELALELARQTGGMIVSADSRQVYTRLTAGTAKPQGQWHNGYYQVEGVPYGLVDFLPVTETFNAGAFRKRAAEIAAQHPDRQLIFAGGTGMYLHAYFVGMDELPSSTPKTREYLSALLKEKGKQGLHAELEKKDPASAAQIPAGNVQRTMRALELFLLTGRPASELKSGHFFKLPDPKTSFWVYLDWDKEILNERIARRTESIFDPMCQETRQLLQEGFAADIPALKSLGYPQAVQYLSGKLSRQEATKQIALLTRQYAKRQRTWFNRYTNALRLPLHTPADFQPRSLARQILVQLAASQQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKE6</accession>
    <name>A0A1Y4DKE6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57398">
        <property type="protein sequence ID" value="OUO57398"/>
        <property type="gene ID" value="B5F75_01090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Csd3_N2" evidence="7">
        <location>
            <begin position="149"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="6">
        <location>
            <begin position="280"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="428" mass="48151" checksum="BEF2C294A0E37D0B" modified="2017-08-30" version="1">MRKKILALLQRHYRRYHDILFYVLTLCVIAVSTFAAVEISRAKNAQERENLHEREIPVAEYTVKEKPIYVALQEAGLDNQLVAQIVSKLSSVVDTRKLQKQNVYSVSVDSDGNFILLLLTQGFKRYYVANVEGALVAGVSDVEIKTRVKTAAGKVEGSLFNSMLSKGLEVPLILDFTDAFSWTIDFNTDTRNGDEYSALWEEHYTASGEITGQDLLAASYKEIERGTTTNAFYFEGDFYDETGKMSRKMFLKSPISFRNYRISSRFSYGRMHPILKVRRPHLGIDYAAPAGTPVQAVADGTVRFAGRNGGYGNFVEIRHANGYTTMYGHLKGYGKGIKSGAKVKQGQTVGYVGSTGLSTGPHLDFRIKEKNKFVDFLKMKNRNSAVRDVPKNKRKEFEELKVLYLKELDAAKKEAFKKPSASEEQDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL14</accession>
    <name>A0A1Y4DL14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57618">
        <property type="protein sequence ID" value="OUO57618"/>
        <property type="gene ID" value="B5F75_02255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="192" mass="21649" checksum="2DD9E6E2B3EA313C" modified="2017-08-30" version="1">MKKWGLVFVFGTLLLAGCTTKEQEQQIRLFWLQQYSNLIVKKLASAPAELANNPQFKKLTASLEQSFGKNLPAQPAAARPAQPQIMEVSMSEDLLPGKASEADRTRMKRALEAVQLSNQSTLTDIAATFGNNVKYQAFLITAQTERQLKKTAEQSATFTAYFQTQQQLLKEQDRQINELLRKNTASIKNIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL36</accession>
    <name>A0A1Y4DL36_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56131">
        <property type="protein sequence ID" value="OUO56131"/>
        <property type="gene ID" value="B5F75_05785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="11"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="22367" checksum="CC6B7749C1739FF3" modified="2017-08-30" version="1">MNIDVINLGPMDNCTYLVTQGQDALLIDPAWDMNFLEHTLAEKKLNLLAVFFTHGHFDHVKFAQDLLEKHHLKAYIEENDVPLCGIAPQWLSVYRGAQKLHVGPFEVEIIPTPGHTAGGVCIKIGNAVFTGDTLFPGACGRVDLPSSNPRHMRQSLLTLSQLPEDTQIFAGHSYGGKCSSTIGCERLKNPFMRNAIRDKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL42</accession>
    <name>A0A1Y4DL42_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57020">
        <property type="protein sequence ID" value="OUO57020"/>
        <property type="gene ID" value="B5F75_04020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="480" mass="53022" checksum="BAFEED1D57AA139C" modified="2017-08-30" version="1">MPIIPTYRRQERYQAPGVQTGAPAPQRLGRAYENTLQEFGSFSSQALAYLQRQPEKEEKKGRSSAAASGVENRLSSLSFEKAENTGGQAEKSSVQADEDLQLRLDLASSVRERVSEGRAVDPSDLDEFAAQRLTPQQADTPAARDYLMLRRAAQEEQALQTRGQNIRAARQEENLVRTVGATASSAAALDAYLEAQLPALEKRLQENGSDPKNLARQLAGVRAQTALENVRRSVAAGNYSAAQEVFSRYEKEMPPRQREECREKIRLSAAEGYANRLWNRAQAETDGTPEQCNAWARQQLTEEKQADLKTDVQKSLDLLAASAQQRQHQALAQVYRAVASAQAGSARAVLNTREGLASARLSLAYRAAQQADGGVSVPTRADTFNTLYFSGTEKEIDRAFEKNQLSARDYCLLQAVLHERAAGAESSESRFLARGIENWGKKNELSVQETAEIKYKVLSADGGIENQRAAWQRMKALLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLN4</accession>
    <name>A0A1Y4DLN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ORF">B5F75_06765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56311">
        <property type="protein sequence ID" value="OUO56311"/>
        <property type="gene ID" value="B5F75_06765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="22"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="126" mass="13730" checksum="5ECB5CC55A8DBE58" modified="2017-08-30" version="1">MHSEENCRFAKTHEWAHMEGDIATVGISNHAQEEISDIVFVDLPKVGQQVTAGQNCCVIESVKSASEIYAPVSGEVVEVNTALANDPALVNREPHGNGWLFKIKMSAPAEYENLMDLSAYKATLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMC4</accession>
    <name>A0A1Y4DMC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56551">
        <property type="protein sequence ID" value="OUO56551"/>
        <property type="gene ID" value="B5F75_04985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="104" mass="12440" checksum="5E956D3AD75B4739" modified="2017-08-30" version="1">MDKTDLENAVFFRAAQRGEDVYGVQGKWVYAGADACLRQLVRIYNQLFEEENYRFWAESEGTAQGEWWHFFKLQQAYPPYPLYRAYRVPFFAKDEALELFLARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMF2</accession>
    <name>A0A1Y4DMF2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57480">
        <property type="protein sequence ID" value="OUO57480"/>
        <property type="gene ID" value="B5F75_01535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="13"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="164"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="534" mass="60713" checksum="2756AD30A5E57C7B" modified="2017-08-30" version="1">MAKKKVEKPINLDNILFNCRNILRGARNSGSFFEKRDMMLTLVFLRFIGEKYEDGIEKLRKTLIEQGLNPDDENIRAAFFDDATFTDGTYNLPKEARWSTIINTSAPALNVALDTALHSIATTSAQLKGCFIEGTFTTRGLAPNDIKKLVDEVNKISHKAFGEEKDLIGRVYEYFLKEFAVNATKEEGEFYTPHDVVQLIASMIEPYEGTLYDPACGSGGMFIQSAELVKARQGDISHINIYGQEKDAATYRLAKMNLALRGLSHNLGETNDSSFTHDLHKGLYFNYIMANPPFNLKGWYNENLKNDARWADYGLPPESNANYAWILHILSHLKPADGVAGFLLANGALNDSDTLAIRKKLIQNDKVEAIVVLPRELFITTDISVTLWILNQNKKGGEYHGRTLRNREHEILFMDLRQWTENTVKNENKKKVRLSTQQIEKASEIYHKWQSTGTDGAHYAVPELYRSVSIAEIEQKGWALTPSKYIEFIDHDLDIDYNKEMSRIQTEMKELLKQEKQSQQLLESAFKGIGYGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMF7</accession>
    <name>A0A1Y4DMF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57490">
        <property type="protein sequence ID" value="OUO57490"/>
        <property type="gene ID" value="B5F75_01585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="130" mass="14938" checksum="08C06A3BDD391703" modified="2017-08-30" version="1">MKQQAECGLINRAELEQQKLEQQTKTLAQVVRRITYAYQGENIEVLLPNGVSFAFHAAVKPNYVRRTKRVNTNPQTPKIDKKTYYKALALQIREYMRVNSLSQRECAAALGMSPARVSQLLSEKREKINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMK5</accession>
    <name>A0A1Y4DMK5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ORF">B5F75_05365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56621">
        <property type="protein sequence ID" value="OUO56621"/>
        <property type="gene ID" value="B5F75_05365"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="145"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="40736" checksum="FE7CC411324195CC" modified="2017-08-30" version="1">MNFIRPFIREGMLALNLVVLYGGKSTEHEVSVHSAQTVCRLLAQQKDKYTVYPVFISKEGYWFLQSSCGPQTPADLPITPVLRPGVHLAALDGSWSLRADVVFPVLHGTNCEDGTMQGFLETLQVPYVGCGVLASAIGMDKEIAKLIARETGAPVLPYRVVSKGKAYDQKELENWAVQTGLPVFVKPVRLGSSVGVRKVKDVSQLNDAVKFALRFDTDVMIEKGVDHAREIFCAIYGDGETVKSSACGELRHLAGEFFDYEAKYITAGGCETKVPADLPEQTAQKMRQDSERIFRALRGSGLARVDFLMDKNGAYYFSEINTLPGMSETSLFPQLFEACGEDYTAILNRLIEMALVRHKQKETLAFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMP0</accession>
    <name>A0A1Y4DMP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4065 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56661">
        <property type="protein sequence ID" value="OUO56661"/>
        <property type="gene ID" value="B5F75_05575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025272">
        <property type="entry name" value="SocA_Panacea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13274">
        <property type="entry name" value="DUF4065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="23"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="150" mass="17471" checksum="110B482EB527AFC3" modified="2017-08-30" version="1">MASVFDVAQYILQRINPISGIKLQKLVYYCQAWHLAWNEGRPLFDDRIEAWINGPVVRNLYNLHRRQTKIYSLPEGNADRLTAAQKESIQKVLDNYGNKEDTWLILRSHQEAPWKDARRGLSPLEASTNEVSIESIHSFYKNKNIENCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DND6</accession>
    <name>A0A1Y4DND6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56911">
        <property type="protein sequence ID" value="OUO56911"/>
        <property type="gene ID" value="B5F75_03445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="18382" checksum="883655BE38EBE655" modified="2017-08-30" version="1">MKKGFTLIELLVVVLIIGILSAVALPQYTKAVEKARTTEAVTLLGDLINAEQIYKMANGSYTNDLSLLDLQLPGVTGTTTQTSTLTKNFQLTIPVATSTTFLAVAQRGTVSGTSFTASTNTDTQYTINASIDANGNIRRWCETAKPTAVLTADKTTGASSICKSIANGNAGGMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNG4</accession>
    <name>A0A1Y4DNG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56941">
        <property type="protein sequence ID" value="OUO56941"/>
        <property type="gene ID" value="B5F75_03600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="470" mass="50386" checksum="E324D91A63F64E8B" modified="2017-08-30" version="1">MKTQRKKKAFTLTELLVVVIVIGVLSAVVLPKFSKVIETRKTTEAEELMAAVRTEQEKRCALDKDYIADLSQLSDIIPSTNTKNFVYSTNESGTGIEAQSKGKYGYTLKMPSYKDGRLCCENEEECLKLNKDYPLCSDLIARADYQSGAECAGDNRPTVVQCVGPSTQTCGCLGKGTQSRVCNTTTGQWGAWGACSAPLFCSCPEDGKPASTQTCNGCGTQTRTVACNTANGEWQPSAWGTCSKTVEECTETEDDCCADGLSSSEFTACILEQYGADSTEYICASGKNLGYIKEIGSIAGASACASKLVGFGSSFLRAANNTCSPTDTYCQQLRSENISWISSGFKKYACTGEKPNISSAPTVDPEPEPGPARFACCRVELAPIITFNNHSGWAYSDCLNAAGNEMAQCPAQVVPGVKMNGSHGGLSCTYKYSCPHEGYQVGSHPYPGFVQTLRCVSYGETCTADEVVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQN8</accession>
    <name>A0A1Y4DQN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57691">
        <property type="protein sequence ID" value="OUO57691"/>
        <property type="gene ID" value="B5F75_02645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="8">
        <location>
            <begin position="111"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="7">
        <location>
            <begin position="300"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="471" mass="50893" checksum="21F1795551268E6C" modified="2017-08-30" version="1">MKIHFIGIGGVGMSALAQLHAMGGDRVTGSDRLISKGYTDMALWDYLKKLGVELYPQDGSGLDHRTELVVLSSAIEDDNPELVKAKALGIPIMHRSELLAKHVAAHRTIAVSGTSGKSTTTAMIYDILAFAGMSPSVITGAAILSLQKEQGVFGNVYKGNSDILVIEADESDGSIVKYKPYLGVCLNLQKDHKEISVLQGYFKEFISHCKTAIINAEEENLRVLAPQAKTFGLSLGDVHPSEIKVDGFGSDFTIQGQPFRLHVPGLHNVSNAVAAVAAALQMGVDLDTCAKALNKFQGIARRFASIGSYDKIEVIDDFAHNPHKLGATIAAAHLRGKRVLAFYQPHAFTSIKLLAPEFVESFAKHIGPQDHLWLTEVYYPGGTIPQGVSCRTVYEGLKARGVNVSYDDCRERILAEMAGAAQPGDILLVLGARDPTLTDFARKLLASLKERQSVSGCKNCMLGNCCLHYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9J8</accession>
    <name>A0A1Y4D9J8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000010">
        <property type="protein sequence ID" value="OUO55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_001974192.1">
        <property type="nucleotide sequence ID" value="NZ_NFJD01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55924">
        <property type="protein sequence ID" value="OUO55924"/>
        <property type="gene ID" value="B5F75_07245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="69" mass="7667" checksum="BC9BEFFF7DD41192" modified="2017-08-30" version="1">MGLISPGGQNLLDFLELRQVLSTYDGALRDPLWWPQERPVPMRVPRGPFGIPLPLMPGPKTLCELRAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAA1</accession>
    <name>A0A1Y4DAA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56177">
        <property type="protein sequence ID" value="OUO56177"/>
        <property type="gene ID" value="B5F75_06055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="133" mass="13828" checksum="39C3AC4006624ADD" modified="2017-08-30" version="1">MGFLKKDSDFSSGEHFSVVSAECYFQGTLSVQGSLRVDGTLEGSVDNARHVIVGTDGKIVGDVTAQIVVCGGVIEGNVCADMLEVLAAASIKGDIRAKKMIVEEGGRIDGQCSIGGGEESAASEKEDKTEKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAG7</accession>
    <name>A0A1Y4DAG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PmbA_TldD_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56227">
        <property type="protein sequence ID" value="OUO56227"/>
        <property type="gene ID" value="B5F75_06305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011562" description="PmbA_TldD_C domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="295"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="566" mass="63318" checksum="68FAD28EEA617A0C" modified="2017-08-30" version="1">MKHFFLMMLGVFLACSLQAQPLCNIEDQRPVQLLEAELARGIKTFKKQKPPIYYLSYTYTEETKNSLEVAEGGVSWEGEIPSRRLQIAARAGSPKMDNTRTLKSDYDNFYIPATTLPDWQGDPRAFETAVWRATQQAAEQAQKDFSRVQIDSINSSKRTDDSNDFVFPPEATYCREEEPLSFDWERLRALLLKASELVQGKDFVLESTFYFSTQEGNRYFVDSVGSRLKTPFAYARLGYELYGKTADGLQLNRSQSYDVLKASELPDEETFLAAVKQSILELEALSRAPEAEPMTAPAILKNRAMAVFVHEVLGHRVEGHRQKDDSFGKTFTDKVGQPVVSPLLTIVDDPTLAYFNGIPLRGFYEYDDEGVKSQPVYIVQDGILKNFLMHSSPIKGFSVSNGHGRRSTGYRPVARMGNTRVMARQTVSYEQLEKQLLSEIKRQGKPYGFIIEDLSGGFTQTGTYSPQAFKLQPTLVYRIYPDGRKELVRGADMVGTPLVSFNKVLAAADDYAVFNGTCGAESGWVPVSAIAPSVLLESLEIEKTGKSNLKPPVLVPPSAEKKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAJ0</accession>
    <name>A0A1Y4DAJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56223">
        <property type="protein sequence ID" value="OUO56223"/>
        <property type="gene ID" value="B5F75_06285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825067" evidence="2">
        <location>
            <begin position="21"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="433" mass="49071" checksum="90DDFB60016D7963" modified="2017-08-30" version="1">MKKLGAFLLAALFLAPAAFAQKEYGLKFSSLMNDNLTLENAIRLGLENNSDFLTAKQDIIIAEQKVSEAKFRYLPQFSLQGTATWYDLDYPMVLPDSVANRFLPGNGLYGDKDQFYGVGITATQYLYSGGRINGTLKMARANLKQVQSRYEIVKNQVVLNIKKAFAQLLYAQYNVKLTQEILDLAETWYARPSGDLWTKVRIRALLADLKSSRNQAASELKKAQLNMLIQLNKELNSRITITGDFEPVKTDWDLPHMSLWAMEFRPELKSAIYALEADNIAIDLALSKRYPDVILNASYEQLGVNDLDDVNKQVSLAVRLPIPYNFSEQIAEKKASQQKSALRRAAIEDKIRVQVAESFENMLFWQNEVLDRQLAYKELNDLMEQAAKDKPKTGTAPLEALQDYLKSAQGYFQAIRNNHTAKAELEWAIGQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAN3</accession>
    <name>A0A1Y4DAN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Elongation factor Tu</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000013">
        <property type="protein sequence ID" value="OUO55855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55855">
        <property type="protein sequence ID" value="OUO55855"/>
        <property type="gene ID" value="B5F75_07260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO55855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="204" mass="22392" checksum="89B0B5987FC5D577" modified="2017-08-30" version="1" fragment="single">MAKEKFSRSKPHVNVGTIGHVDHGKTTLTTAITKVLAKEGKAKAMAYSDIAKGGVVRDASKIVTVAVSHVEYETEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVSAVDGPMPQTREHVLLAKQVNVPKLVVFLNKVDLVDDKDLLDLVEEEIRDLLGKYEFDRDNTPIIRGSALKAIEGDQSELGEPSIHRLMDALDTWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAN6</accession>
    <name>A0A1Y4DAN6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56264">
        <property type="protein sequence ID" value="OUO56264"/>
        <property type="gene ID" value="B5F75_06515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="93" mass="10263" checksum="6BCAFF9000385DF4" modified="2017-08-30" version="1">MLDIDVSSSLDCEGSFAGTCGSKNYSYSIFCETKRCEIQFYRNNGDTNDYYKGYVSTSDGSNWGGYCGYESALGKPVCDMFATMGNNVMVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAR0</accession>
    <name>A0A1Y4DAR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56307">
        <property type="protein sequence ID" value="OUO56307"/>
        <property type="gene ID" value="B5F75_06745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="228" mass="24986" checksum="6041E1436ABBABC2" modified="2017-08-30" version="1">MVRLLKLLIALLLLPTAVLTFAQTVRILLAVLGQLSAAVSFIAGLVVYSGIHYGYYNFSRPYVFAHEITHALAALLCGCRIKDVSIGQDSGYVKMDRCNAFVVLAPYFVPAYVIAAALVYVIADLFVDVSPYRQVFLFVIGFFMAFHFIQTFKTLFEADQPDLKLAGGKVFSVVMITLANLVVLAVVLKALFPETVSLLEAGKNVLAGTVNIWRIIVNYIVEKAINAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAU9</accession>
    <name>A0A1Y4DAU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56186">
        <property type="protein sequence ID" value="OUO56186"/>
        <property type="gene ID" value="B5F75_06100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="151" mass="16618" checksum="F90F94196ECBCBFB" modified="2017-08-30" version="1">MKTLLLIRHAHALPAYEAGVPNDALRPLSEPGRQKAARTAKAIAGKGLHPQIVFSSPLLRAVQTAEIIAQTLHAPLSKETVLNGLYDEKDVRDFLAEQFNTYDTIAAVGHNPNVSYLTHLLCAEVHSFMPGSFAWVDMTDPKNPRLTYFGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB47</accession>
    <name>A0A1Y4DB47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56276">
        <property type="protein sequence ID" value="OUO56276"/>
        <property type="gene ID" value="B5F75_06575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="2">
        <location>
            <begin position="72"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="372" mass="40549" checksum="5C8965C9FB01C38F" modified="2017-08-30" version="1">MAQNAAQAGSIAGRPGGGFDRSYQHAGIAGAAVRNGRVARAVRLGRAARRLITQEINMKPARIVFPGFWFGQSSLQEAEELTRRGVGGFCVYGGTAQETKDFTKRMNDLSPYGKLLFCADIDEDLSEIVTDAPALPANETLQHFSCPQDGAYRKGNLIARMARSMGLDWVLCPVVDLGYAPPAFSDVPLTVTHLAGDFIAGLSNGGALNCIKYFPGVSGVLKTLAQMEDAEFVPYKHIFRRADAIMPSDMIFPNIDNDHQAMLSDRVIKGLLKKRLNYKGCVVSFPLFKGRLRYEDASAIKMLHCGVENILAPKNASSVVDAVEKEADKGLLMDEIIHAVSNHEMFISKVYVGPEPPDIAEAFEMAKAFCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB76</accession>
    <name>A0A1Y4DB76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_06795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56316">
        <property type="protein sequence ID" value="OUO56316"/>
        <property type="gene ID" value="B5F75_06795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="19685" checksum="ECCAC21055EC8FA8" modified="2017-08-30" version="1">MKAFLVLFWIFAKIGTFTLGGGYAMLPLIEKELVDKQAWLDRKEFLDCVAVAQAAPGILAINVAILAGYKIKNFWGSVIASLGAALPSFVIILLIALFFNEYEHNPVVQRVFMGIRPAVVALIAVPVFNLSKAAGITYRTVWIPAVCAGLVWLLKVSPVYIILAAGLGGFLYARHSRRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB96</accession>
    <name>A0A1Y4DB96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="6">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">queC</name>
        <name evidence="8" type="ORF">B5F75_05755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the QueC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56125">
        <property type="protein sequence ID" value="OUO56125"/>
        <property type="gene ID" value="B5F75_05755"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="228"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="359"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="615"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="636" mass="67512" checksum="FBC2C8D8762D3AD0" modified="2017-08-30" version="1">MNVLIARTIEECEQWTDVAVVVDVLCASTTVCALLKRGKKDVLAFGDAAQAAAFVQAHGDFEVYSDVDFALPHENNSPSLAAKSNARKPALVLTSAGTKALEHLKQASLVLMGGFCNFYALAEALAAQPKDILLVSGSLFDMADDVEDGLCVSALKDYIQGIGNPQDAIVEFNNTMRFGEFLHSGSKTAEKDLKTAFKVNGIAVVPQVSFAPDGYGVCHVFGQPAPQEWMGKQPSSAAPEPAPQAAAPAEETPAPATVPQQPAPVQESTPAADTLQTPAAENTLRKEVKTAEKNLQAAAQQATTRLKGFFSGILKAVKEEKAELEGDLGMAQKQAESPKTAPQNQFEDPLDRVLKKSERAPAPQENHPARPAEPEAPAAPEQEAAPQPSPVQAAVPAGEVTFSREAAAGLSNKKRKKAIVLFSGGLDSTTCLYWALAHGYECEALTVSYGQRHEREVQSAQAIARKLGIKHHLITLDLPWLSCCSLVDKNKQLPDIAVEDIPKEGIPSTYVPGRNLMFLAIAGSLLDAVGADAIIAGPNAVDFSGYPDCTPAFFKAAAEALNRGTKTGVSEGIEVLAPLMRLSKAQIVKLAANLKVPFELTWSCYAGGKKPCGHCDSCKLRAKGFEEAGVHDTSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBD2</accession>
    <name>A0A1Y4DBD2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56175">
        <property type="protein sequence ID" value="OUO56175"/>
        <property type="gene ID" value="B5F75_06035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012938048" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="41"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="203" mass="23079" checksum="2D7C18E26A50FE96" modified="2017-08-30" version="1">MKRFVCLSVWLCLSIPCFSQIYRARDYTAQEEPARFTAPRWEVSAGAAAFSGQMHDFTGQRLVQGELGAEVRAFYSLADWAAVGVSGGVSGPLKKTELVDKYRTYRLEALLKVTLTPQASPRSYITAGMGWQQHDVSYFSLWQEKFSVPFLAFGAGVETAFSENWFGGLELRGMYHLQSARNVYFYFPHRWEAAVHLRTGWMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBJ2</accession>
    <name>A0A1Y4DBJ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56436">
        <property type="protein sequence ID" value="OUO56436"/>
        <property type="gene ID" value="B5F75_04375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012960736" evidence="1">
        <location>
            <begin position="26"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="430" mass="49289" checksum="77403C6BC0607D33" modified="2017-08-30" version="1">MKTQPRFWIPVFLCLFWLALPPVQAQAVSPWFRGGKQVWETLLKHNPALVSGRAALSIPLSHTVTGFSVKTTPYNWLLHRVSHSGVFSRMEKEILLQKTSSEKAALGKLAYFHDRDAHLFNALSLYPQAQADEPAFWRHQNLLTNTLAELEEFYRPLLPEKLTSSLFTKEAVQHLLADPVQPPAFVLHVKEISSFAALNTLAEQQAWARNILHQTNSDLNALLAKDPQTLKGYEFERYYLQKLRLEYFKTLQEVLQNAVAKRPSLIIRRKRVLKINLPGAGQPMTDAQRLGFLRYYMDRLARQADLTQKENPAFAQYLQVKTVLQTLAPVYETYAAAEAFGVPYEHVLRVGSSWPDLIVGAEEGQQLRQTIGKTPLTQLPAKIDELKSKMALMQAQEPDGLDFFVRYYRLERTKALYETFLIRERLLRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBJ4</accession>
    <name>A0A1Y4DBJ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56235">
        <property type="protein sequence ID" value="OUO56235"/>
        <property type="gene ID" value="B5F75_06350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="6">
        <location>
            <begin position="174"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="265" mass="28646" checksum="C52C10D369CBC8DE" modified="2017-08-30" version="1">MSNIHPTAIIDPAAQIDPSTTVGPYTIIGADVVIGKNNKIGPYCVIENTTMGDGNELIASSFVGVKPQDLSYNDEPTRVTIGNGNKIRECVTIHRSTKLDCPTSIGNNCLLMANSHIAHDCHLGNNIIIANSTGVAGHVVVEDRVVMSGMVGIHQFVRVGTMAMLSGGAMLPLDIPPYCIAQGERARLVGLNIVGMRRGGLSRETILEIRRAYKLLFRSGKRLQDAMDELEATHPCKEVQHMIDFCRASSRGVATAKRKVNENDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBJ7</accession>
    <name>A0A1Y4DBJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56534">
        <property type="protein sequence ID" value="OUO56534"/>
        <property type="gene ID" value="B5F75_04900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="326" mass="35445" checksum="AE8FF6509B0CA44B" modified="2017-08-30" version="1">MTCSSEPILEVRNLHIDFTTEEGRLPVLCGLSYALPKGRVLAVVGESGSGKTVHALSVLRLLPPNAHVSEGEICYKGQNLALLSEGELRRIRGGKISMIFQDPAASLNPVLTIGQQLTETLLAHRKISKEEARRQAARLLEKVGIVGAAKRLEEYPFQFSGGMCQRVMIAMALALSPDVLIADEPTTALDVTVQAQILRLIKQLQAESGMSAVFITHNLAVAAAVADEVLVLYAGRCMEQAPAEQLFKNPLHPYTQGLLNSLAPLHQKVDELPVIAGHPPVPGKTQAGCPFAPRCPFVSEKCRKSCPPLFEENGRKTRCWLREVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT1</accession>
    <name>A0A1Y4DBT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56603">
        <property type="protein sequence ID" value="OUO56603"/>
        <property type="gene ID" value="B5F75_05270"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20937" checksum="E7C03CDCF983E0D1" modified="2017-08-30" version="1">MDFFKPDIAGLAVIVPQVFEDERGYFFESYQAEKWREACGGAVFVQDNESFSKHGTLRGLHFQKPPYAQAKLVRVLDGVVWDVAVDLRRTSPTFGRWFGVELSAANKKQLFIPRGFAHGFSVLSPSARFAYKCDQLYHPEAEGAIYFADAELNIDWKLRPEEAVLSEKDAQNPSFACYKEHPCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT3</accession>
    <name>A0A1Y4DBT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56604">
        <property type="protein sequence ID" value="OUO56604"/>
        <property type="gene ID" value="B5F75_05275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="294" mass="32742" checksum="256B43701372A6BF" modified="2017-08-30" version="1">MKGIVLAGGTGSRLYPATFAVSKQLLPIYDKPMIFYPLSVLMLAGIRDILLISTPKDLPLYRHLFGTGDAFGIHISYAEQPRPEGLAQAFLLGEDFIGNESVCLTLGDNIFYGRDLKQLVQKAAARPRGATVFAYHVKNPQAYGVVEVNAQLQAVSIEEKPRHPKSNWAVTGLYFYDNRVVNIAKQLKPSARGELEITDINEWYLQAGELQVELMGRGMAWLDTGIPTDLIKASMFVEALESRQGLKIACLEGIAFKNGWIDAKQLARRAELMKNTEYGQYLAHIPEDMKNGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY3</accession>
    <name>A0A1Y4DBY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56647">
        <property type="protein sequence ID" value="OUO56647"/>
        <property type="gene ID" value="B5F75_05505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="686" mass="72331" checksum="E0DD17FD1C392DBF" modified="2017-08-30" version="1">MSEEQKTIISIFSIYDNKGDIAAQKGMEGVAKKAEKVGKASVSAGKEGSNAFNLLQSSIARVAAAFMAAKGIIEFFSSSVSEYQEHARNVNMLAAAFQNVGYTASGAMQQALAFADEMERSTGLDGELFIKGQRALANYGVVGAQAQEAIRAAFALSANQGIAFESALQLLTRAAAGSTATLTRYGVVLGENVKEGQEFEAAVKQINEQFGPSAQAAIGDTTAKMGALREAWGGFKEVIGQGLNEGLAPAVEWLTEAMLWLQKAFVAGGNSYDWFLGIIQAGTAGARAVILNFADVALKAFGKIVEIGNKLHLIPDGVAEAVKSAEEWISQAADNAEQQTATLNRMRRGITEIWPAEQKITEEQNKQLEIQAQQINAARQKKHQAQGEASAQGEVTNELERQQKILDNLGLSSSKDLKGWNRNADNSEPGPTGAEIFAGGDSDLGGAADAVAQYDAEAERLEELRELKLSYIEQEISDETLKQEALRNLEAQYNQQKLENDKKQAKARQQVYGTMWSALSGLASSENKKVATIGKVASIAQATMSMFTGAAKALELPFPANLAAVATVLAQGAALVQQIEAVKLANGGLVRAVTGGVNAVIGEGGSDEAVLPLDNTQAMRRIGGAIAEESDGLGGSVVVNVNINASGGLQPFLEQLTEATQNGVTEALRYANVAVKAGNAQGGLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC40</accession>
    <name>A0A1Y4DC40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Anaerobic ribonucleoside-triphosphate reductase activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_05845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56142">
        <property type="protein sequence ID" value="OUO56142"/>
        <property type="gene ID" value="B5F75_05845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012840">
        <property type="entry name" value="NrdG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01094">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02495">
        <property type="entry name" value="NrdG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="13"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="207" mass="23349" checksum="2EDE12AFEA712D1B" modified="2017-08-30" version="1">MKIGGLIKFTLIDFPGRPAAVIFTQGCNFRCRYCHNPELVYPHMFTEPVAEEEIDAFLKRRQGTLEGVVVSGGEPTLHDDLPQFLAKIKSMGYAVKLDTNGTRPEMLRQLIQDKLVDYIAMDLKAPLEKYSLITGVDFNPAILRESMDLIKKSGLGYEFRTTYDKEVLTDADIAALSQMLNGQHYRVQECLPVAKEKAALKVLHKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC77</accession>
    <name>A0A1Y4DC77_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56666">
        <property type="protein sequence ID" value="OUO56666"/>
        <property type="gene ID" value="B5F75_05600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="119" mass="13093" checksum="30D7961FE1A4262C" modified="2017-08-30" version="1">MANFYGPDSALQSSFKTPSNMLCPVCGEYGRASFAVFVDMGDNKPMIHVCNSLVCLGCKENGKRGRLVALFTGPVSNPDFSNRGAKLPPGITLDTVQKALIKNPTRRWFSWGELTNRMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC91</accession>
    <name>A0A1Y4DC91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin attachment protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56202">
        <property type="protein sequence ID" value="OUO56202"/>
        <property type="gene ID" value="B5F75_06180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="524"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="598" mass="64088" checksum="D523F92D14A2B8B2" modified="2017-08-30" version="1">MKKINFMLTAFRDGFQSVYGARVLTKDFMPAVEAARHAGINHMEFGGGARFQALFFYCNENAFDMMDTFRKTAGPDANLQTLARGVNVVGLDSQPSDVIKAHAQLFKKHGTTTIRNFDALNDVNNLIYSGQCIHDAGLKHEVCVSMMSLAPGWDPTGQIHTEVFYEKILRQILDSGVPFDSVCFKDASGTSTPATVGKTIAMARRLLPKGTKIVFHTHETAGNSIACCLEAIHAGADQLDLSMQPVSGGTCQPDILTMWHALRGTEYTLDIDPKKIQEAENVFQDCMSKYFLPPEATAVNPIIPFSPLPGGALTANTQMMRDNGTFDKFPEVVKAMGECVKLGGFGTSVTPVSQFYFQQAYSNVMFGPWKKITPGYGKMVLGYFGKTPVEPDPEVVKEASQQLGLPPTKKTPLEINDADPKKGLKVAEAKLKEAGLPVTEENVFIVATCADKGLLYLKGEAKVNGIRWAADAKKAAAASSGAVKVTVNGKAYEVVFDGDSAVVNGKRYNVSTAASDAKAEAKPAANTGAGGTVKSPLPGAVLRLSAKDGEHVSEGQEIIVLEAMKMETAVSATASGTVHFLVKQGDQVQTGDALAEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM9</accession>
    <name>A0A1Y4DCM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="6" type="ORF">B5F75_03460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56914">
        <property type="protein sequence ID" value="OUO56914"/>
        <property type="gene ID" value="B5F75_03460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="34"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="239" mass="26623" checksum="67DADEEA1D5EFF14" modified="2017-08-30" version="1">MMSSKISAEPQKSGLLLLDKPADFSSHDIIAISRRILKTKKIGHSGTLDPMATGLLILLVGREATRRQDAFLKLPKTYQARLQLGAETDSWDAYGEVTRQTPVPPLTPEQVRQAAQALTGTIRQPIPFFSAKRIGGKHMYDLARQGLPMERRYNDVTVQWQDIRLLAPDKIEFTVFCSCGTYVRSLGYLLAKQLGCAGHLTALRRLQIGPYCVQDAFDGNLLKNADAQVLYARVTPIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN3</accession>
    <name>A0A1Y4DCN3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SpoIID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56873">
        <property type="protein sequence ID" value="OUO56873"/>
        <property type="gene ID" value="B5F75_03235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02669">
        <property type="entry name" value="SpoIID_LytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013073780" description="SpoIID domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="163"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="3">
        <location>
            <begin position="399"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="700" mass="78620" checksum="63137B257C73EC71" modified="2017-08-30" version="1">MKHFLVFIALLAACAFPAAANTPAAQTEEQRLQEAGDLYFAYKQDDALEAYIALSKDTGNRQAFLNAAFIAMEQNNPKQAVDIMSAAYKLHPQDREVIEMAAEAYLADGQYITAEKFLSLLPEDPRRAGFFHINLARAQMGLGEKKLAKYNLKMAARAGTHPALANYLLGILYEEEKDYKKAADAFRKATVYDHQFIEAKKHYAAALEKLGNYNESYRQYRMIYSSEKNLKDVNAALARLKPRLTRPEKEITGGKEIIKHTFVKPLLPPENVKTKQIKIGLGMRSNGRPSARNTVHFIPSHDFTVTDAQTGRVLARGKAKESWVAVLKDGKAHLLTPANKKIFFKKSVIVTPRSNTQGEGHTIIVKNVMSGAGMTWASVDDKEYRGQLQITHNTTLNTLIPINIVNIEEYLQGVIASEMPTQFPMDALRAQAVLARTYALKHLGKHKYYGYDLCDTQNCQVYGGVTSESERGNAAVESTMGEILTYENKPIESVFSANCGGVTQSAKEAGWYDTPYLQPASDYKDFDFDQLQPYHFKELLQYPHDAYSRYDKNVSLAAFRWTRVVDEEDLSQLIKRQKKDIGRITALIPQRRGRSGYVSRLLVKGTKGNLTLNKENVIRNNLSLGMLRSSYFIVEPNYQDRELKFFVFYGGGWGHGVGFDQTGAAGRAEDGQGYKEILQHYFPLATFESPSQKSAQPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN7</accession>
    <name>A0A1Y4DCN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisS</name>
        <name evidence="10" type="ORF">B5F75_03255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56877">
        <property type="protein sequence ID" value="OUO56877"/>
        <property type="gene ID" value="B5F75_03255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="20"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="45730" checksum="28773672ED6253C1" modified="2017-08-30" version="1">MSKLVRGFRDIFEPQSKNFTELENCARGVFSLYGFGELRLPTVELKELFIKSTGETTDIVQKEMYAFEDAGHRQLAIRPEGTPGVVRAYLENNFTQNAPVQKFYYIGNMFRAERPQAGRYREFEQIGAEYIGNSAPAADAEVILMLKDIVAKFGAKNYKVKINSLGCDKCRPLYRQELIDFLSAEKDTLCENCQTRLEKNPLRVLDCKIDGSRFAGRVPTMKLCPECQAHFDEVQALLKGKIDFEVDPMLVRGLDYYSRTVFEFQAGDASQNAIAAGGRYDTLVKHMGGPATPAIGWAMGAERVIMARGETVPAKQKSVYVVSLDKTCNETAFNLMQTLRHAGIRTEGGLFDKNVKGQMKQSDRCGASYALILGEDELAKQAVTLKDLTTGEQKQIPFEALTDEVKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU3</accession>
    <name>A0A1Y4DCU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56432">
        <property type="protein sequence ID" value="OUO56432"/>
        <property type="gene ID" value="B5F75_04350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="2">
        <location>
            <begin position="6"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="396" mass="45487" checksum="B3FD4E1CFC96C2F7" modified="2017-08-30" version="1">MARNLSFSYSKMGMYKECPQKYKFRYVYMLPEQPKYYFAFGSALHEVMEYIYNPANAAFPTLAQALDFFEKHWNKTSYEQKGYASVEKELAGYAEGRRIIESYYAQNAAHFFHPLSVEMKSTLEMDGLNLISILDRIDYLGDGKVKILDYKTGKTVQREPDQLYMYQKVVENSPAVKALVQKVDPGVKELRVGQLSFYHLPTLHEMTFERAPDREIFEFWQGVLKVADNIRAGKFDPTPGENQCRWCDYRNICPVFTGKDYNPASAQGAKETPAAAPQNEQDELSDKIDRCGALLDEAKQLQREIIALMKKNHFERHFGRQYKAELSRIEKLEFTDKEKVVELLRTLKLLGKVLVPTQSTVAGLLQDASVPAQAKEKLQAFAVKTEEEKLSIDKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU6</accession>
    <name>A0A1Y4DCU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cadmium-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56846">
        <property type="protein sequence ID" value="OUO56846"/>
        <property type="gene ID" value="B5F75_03090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="638" mass="67342" checksum="2C5A5FBE91239D60" modified="2017-08-30" version="1">MSQDCKQTPCHDCSACAAAHGQETHPEENGWKKLALAAVLFAAALLLPAEGWVKLPLYILSYLISGGEVLVKSLQNIRQGKFFDENFLMTIATFGAFAIGEYPEAAAVMLFYQIGEMLQEAAAGKSRSSIVKLMDLRPDFARVIRNGKEEKVSPQDVQIGETTLVLPGERVALDGVILSGSGHIDTSALTGESRPVGAKAGQEVLAGCISVDGTLHIRTQKTYAHSAVAKILELAEHAASKKSSAEKFITRFARIYTPAVVAVAVLVAVIPPLVWADASFKTWFYRALIFLVISCPCALVLSVPLGFFGGIGGAAKNGILIKGGSYLERLAHIYTLALDKTGTLTQGVFEVTAVVPADGVQAQEVLELAARAEGHSNHPVAKAILHAAKAQKRPLTEGESVLERAGEGIEYKQGQDVILAGNARLLERFGVEGMQAGSGTCVYVAQNGVYKGRLELGDMPKPGAKEAVKQLKKLVKELVILSGDQPSAVEKTAQELGITKAYGGLLPAGKVEKVEELIANAPKGAVTAFAGDGINDAPVLARADLALAMGALGSDAAIEAADVVLMTDEIQKIAAGIRISRKTLRIIKQNVVFALAVKAGVLALGVMGMANMWAAVFADVGVSLLAVANSLRPLYFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCV4</accession>
    <name>A0A1Y4DCV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56953">
        <property type="protein sequence ID" value="OUO56953"/>
        <property type="gene ID" value="B5F75_03660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="31"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="234" mass="26431" checksum="9D284CA9D38138EC" modified="2017-08-30" version="1">MNREETLVANFQNVRQALLSACQRSGRDPKEITLLAVTKYAKDQDVLTLLQKGLIVHVGESRVQQAQARWEKPEFARFHTVKHFIGHLQKNKAAKAAELFDFIDSLDNFDTALALEKHVPQGKTLRALVQVKLTDKETQSGLPLEEARQLARRLKTLQRVRVCGYMAIAPQGADETRLRQLFRPLKQAFDEDFKSLPEKYLSLGMSADFETAVEEGSSLPRIGSKLFAENLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCY8</accession>
    <name>A0A1Y4DCY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56983">
        <property type="protein sequence ID" value="OUO56983"/>
        <property type="gene ID" value="B5F75_03810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013232116" evidence="3">
        <location>
            <begin position="29"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="113"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="685" mass="73480" checksum="0AC294E71D0281B5" modified="2017-08-30" version="1">MIKINKFWNYLIVAFFCFALTSGSDVFAASAAKQLARGIDLYEQNKDSEAMDYFIDVMVSGDKDQVAEANKYVELIHNRMGGIQTPVEVDINFKEGEVKSLEDVTDASVRAAQEQAQAAAAQAAAQAEAAKAQAAAQAQAAKDNALAEVNAQQQALTERIEANRMAAQQRADQARQEALAQAADVNEAALEAATVNATAGSLGLSATDQADQEAIDSQTDAVLNAAEENEPAPVQQPAPRQEQVLSSTTTQPAPVTETAPAESVPAEETASSTFADLTSPEALEAREIYTRQKIESMSAAAADKITAAKGVNLYFRDGMPDALDMEADVIFQGNKFRPEGLALLDNIYDLMALTQGAAYVILPPGSYTDDVTLSGIRQAMALNSYFVNRGISQGKLHYNMGLVDQEPPARFANLNGLAIVFDYAAKLPTRLEKNENNQKAPLLSMAIVPQCHAIDRALGEAYAIDFSVLETVNPVDNWVLQVVQHGRDGKYYVVRQLEGFTPVYHQILWNGRKGIIGPELPCGKYTLVLTATDLKGQKQTLRRRVIVKCSEQKVTSSSSTTCNTASCQTAAADELCPKCNYKASRLWVKPGRTMKAVQQAAPAAEAAASETDPYAMPDTLAPASSDIPDTLTYSTGTAAANPAYAPMADSQQPYAAPQSTATGSSAPAELPVNNPYDMPYEQYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCZ6</accession>
    <name>A0A1Y4DCZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56993">
        <property type="protein sequence ID" value="OUO56993"/>
        <property type="gene ID" value="B5F75_03860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="108" mass="12106" checksum="C87C738210057BAA" modified="2017-08-30" version="1">MSEIFFSTDPRFCSHCKHIPCICNRLGAPKKQTEPVRVRFAKNAKGSGMTLVERLPLHPEGKEELLKKLKKSLGCGGTVKEGRLEIQGEKKQQTAALLEKEGYKVRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD51</accession>
    <name>A0A1Y4DD51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56552">
        <property type="protein sequence ID" value="OUO56552"/>
        <property type="gene ID" value="B5F75_04990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="462" mass="50002" checksum="37774C3F456338A0" modified="2017-08-30" version="1">MKSGFSINIYGLIFAIMLVVAALTYLLPAGQYDTVQKDGRSYTVAGSYHAVASNPQGLASVLTAPAKAFGDCADIIVFIFITGAIFTILERTGTVNAVILGTSYLFSRRERLKKFFIPASMVLFSLGGAVFGMEEETLIFIPLFIPLALSLGYDTVVGVSIPFLGAWVGFGSAFMNPFTVGISQGIAQLPLYSGLGYRLAVWAVCTAVVILFVTLYGERVRKHPQKSLTYEADREKRKQLHLNVLEKPEFKRSHILISIVFALGMAGLVYGVAVYHWYIIEISGLFLGVGLVSAVIGRLSLNQTTDAIIDGARSMVSVSIMLALARAIVVIASDGRILDTVLHSIAQAIGQLHPLAAVEGMFWAHSFINFFVASGSGQAVLTMPVMIPLSDLMGISPQLSILAYQFGEGWTNAIIPTAPVTMAALGMAGIPWLKWARWNVPLQIVLAVLSMLLLIPPYLMKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD59</accession>
    <name>A0A1Y4DD59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_02875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56805">
        <property type="protein sequence ID" value="OUO56805"/>
        <property type="gene ID" value="B5F75_02875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="336" mass="36009" checksum="AE862515D8D503C4" modified="2017-08-30" version="1">MIKVGINGFGRIGRFVFRAAQERNDIEIVGINDLCPVDYLAYMLKYDTMHGKFNGTVEADVANSQLIVNGKKIRVTAEKDPANLAWDKVGAEYVVESTGLFLTQEKAQAHIKAGAKYVVMSAPSKDATPMFVVGVNEKTYVKGTQFVSNASCTTNCLAPIAKVLNDKWGIKEGLMTTVHSTTATQKTVDGPSMKDWRGGRAASGNIIPSSTGAAKAVGKVIPELNGKLTGMSMRVPTLDVSVVDLTVNLAKPAKYEDICAAMKEAANGELKGILGYTDEAVVSSDFLGCPLTSIFDAKAGIALTDTFVKVVSWYDNEIGYSHKVLDLIAHMASVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD68</accession>
    <name>A0A1Y4DD68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnS</name>
        <name evidence="7" type="ORF">B5F75_03270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57074">
        <property type="protein sequence ID" value="OUO57074"/>
        <property type="gene ID" value="B5F75_03270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="132"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="432" mass="49226" checksum="48ADCEAE1FE36A57" modified="2017-08-30" version="1">MSSKYRVKDVGQYLGQEITLKGWLYNKRSSGKLHFLQLRDGSGIIQCVMFKGDVSPEQFELGDKVTQESSIIVTGTVREDKRSPLGYELGVKNLEVLQMAKDYPISPKEHGPEFLMNYRHLWLRSAKQTAILRIRDEIIFAIREYLHKNGFVLADSPILTPAACEGTSTLFETDYFGEKAFLSQSGQLYAEASAMALGRTYCFGPTFRAEKSKTRRHLTEFWMVEPEVAYNDLDDNMDLAEDFIKYIIRQVLTNRAADLKTLERDTSKLQATVEKKFPRIDYTDAIEILHKKGNNTPWGGDIGGDEETLLGEDYDTPIMIHRYPAAIKAFYMKRDPKNPKVVLAVDVIGPEGAGEIIGGSEREADYDALLARLKEQGLDPKGYEWYLDLRRYGSVPHSGFGMGIERMVRWICGLQHVRETIPFPRMMDKIHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDF1</accession>
    <name>A0A1Y4DDF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56905">
        <property type="protein sequence ID" value="OUO56905"/>
        <property type="gene ID" value="B5F75_03415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041603">
        <property type="entry name" value="YvdT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17934">
        <property type="entry name" value="TetR_C_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="22599" checksum="27CE5F4AACCC3BD9" modified="2017-08-30" version="1">MTDSQSYSLRKRGLMDTKTKLVNAAMAVFKKKGLEKTKVSDIVKQAGVAQGTFYLYFSSKLSVMPAIAQGMVLKMREELTNTVNPAAPLPQQVDQIVESIFKTVDKHRDILAFLYTGLTQSADITKWESLYAPIYEWIKQFLQRNCLSLRAGMNAPYTARLLIACIEEAAEQVFLFSHRDAQEAARQQEETAVFVKHALGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDS7</accession>
    <name>A0A1Y4DDS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57025">
        <property type="protein sequence ID" value="OUO57025"/>
        <property type="gene ID" value="B5F75_04045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="195" mass="22145" checksum="ADCB8285ADE1487F" modified="2017-08-30" version="1">MISKITICNLALAQLGQAPISSLEQDDEKARRLNLFYEPVRDEVLRTHNWAFAGAEEPLVLIEKPQEAPGRCIYKYPAEALFVRRVFVPEQAVKALKFREVFRTDLHCRVLEVPAERAYAEYTRRILDENLFDPAFVKSFSLALACDLAIALTGDSALASQLLQKYTLSLDEARRSNMTENFTRADASDAFTEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT9</accession>
    <name>A0A1Y4DDT9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57283">
        <property type="protein sequence ID" value="OUO57283"/>
        <property type="gene ID" value="B5F75_00450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012847900" evidence="1">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="313" mass="36089" checksum="BA288E1ACBFDE128" modified="2017-08-30" version="1">MVKMHTFIWEIFSLFLCSYAAAQPFTADFSALSDARRELHQEKYELFPTPPFLTVYQKGDKKLVLLAARHGAESLPSVQYAFDVYAPQVALVEREPAEVFGGPCTEAEDSYTAALCGKWQIPLVRADLSLEKQWQFAKENGFSYEDWQMLWMIRDGYGRARETDQPFTPAEAIASYAKRDHHAAWGELFTEKRLNAYFKKYYKQNFAETDFIRLYQDLMNIYPEKWVTKTPFYRLNHAAGLARSRFMLQNIAAALNQYDVVFAEMGAGHYMDLVLALEKMLGDPQVIDGRRLPPQNLWKDCTVEGVEEIVLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU1</accession>
    <name>A0A1Y4DDU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57206">
        <property type="protein sequence ID" value="OUO57206"/>
        <property type="gene ID" value="B5F75_00035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="268" mass="29989" checksum="DAECFC4604606189" modified="2017-08-30" version="1">MTDKDLNEMFEGKKQAAPAAPKHVFRLHRRLFLLVFAVAVLLQSVVFVDMRLGSYYRELNDSFKVILTVSAQTPNEELEQMGESLNQKTDILSVRLFSPEDALAAVERQNPQLTDALLLMGKNKMPAYFELRLNYKAINNIRPFIDNLAAEYPGLEPHYNADHARLLFYTGLCAKLLNLAVIFAVLLFLAFMFLVEAYPSNQVRAHYFGGAVSGVLAGLASCAFFAVLVYPTGFLAAAAAQFTTPGRQLLMLAFCGLFGWTLSKWQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX5</accession>
    <name>A0A1Y4DDX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57075">
        <property type="protein sequence ID" value="OUO57075"/>
        <property type="gene ID" value="B5F75_03305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="139" mass="15431" checksum="1001C15A9EE55AD5" modified="2017-08-30" version="1">MGGLDCTARLSPKYFADVFAAPNQITQVNVALSFSVASHEILVRGNISGKRRVQCARCLKMTEQPFAEEFLETYSNKLEIIDIMLLVRQTLALTEEIRFLCKPDCKGLCPQCGQDLNEGPCACKPVNLSPFAELKGKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX7</accession>
    <name>A0A1Y4DDX7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57324">
        <property type="protein sequence ID" value="OUO57324"/>
        <property type="gene ID" value="B5F75_00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="144" mass="15946" checksum="BF6D8CDB433EC31E" modified="2017-08-30" version="1">MKMRPAVTLDAPRLAWIESTQPMSAHWGEKGFAGEIANAASHIWCWEENGEVQGFLALRLAADMGEILNFAVCPARCRRGIGFRLLAHALRDVRARGGRTVTLEVNVTNLPAISLYTKAGFSEWGRREKFYGGTDDALIMGIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY8</accession>
    <name>A0A1Y4DDY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56862">
        <property type="protein sequence ID" value="OUO56862"/>
        <property type="gene ID" value="B5F75_03175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="78" mass="8754" checksum="FA2127B53F1CFA6B" modified="2017-08-30" version="1">MNRLSLLLKDLLLLLLNIFMLLVRPFLGPRGVCRFEPTCSQYAKQAITKHGAFKGGWLALVRVLKCHPLHPGGYDPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE33</accession>
    <name>A0A1Y4DE33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="2" type="ORF">B5F75_03450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56912">
        <property type="protein sequence ID" value="OUO56912"/>
        <property type="gene ID" value="B5F75_03450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="119" mass="13535" checksum="3A7C0CAB5A6F1479" modified="2017-08-30" version="1">MIDRIKRLETLFLEEINTLITKMAANGDFGGFVTITAVRLSKDLANAKVFFSVFGSPEDKKKTQEALSLLRKEIGAKLRGRLHLKRIPSFSFEFDDTPEKASRVESIFQILEKEKQDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE34</accession>
    <name>A0A1Y4DE34_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57384">
        <property type="protein sequence ID" value="OUO57384"/>
        <property type="gene ID" value="B5F75_01015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="22"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="336" mass="37420" checksum="AFDAC53E919CAB6E" modified="2017-08-30" version="1">MSKISAEKLNTELAKNTVSPVYLLTGEDVYRKNLAIQKIREVLHPDDFNSYQSEADKADLGEVLALANTAPVFSENRLVVLTGIEKLRKDPKEALIRYLDNPLPTTTLVLTHNDAKKMKTEKVLAEVCSDAGRVVSFDELKKDELNAWVRQKMQEKGLQPDFDSVDLLCESIGGELNALENEIEKLSLYTADRADKHITKPDVLACIGFSKEENPFELSNAITACNKNRAVQLVDKLVDDGEEPVSILSKMTFPILKMARIKRLSQAGMAPAEILRAAGLMYWESRLVNQARLFPSQSHFLSALNRIIEADAAFKSSTSSDPKILLKGILLTLFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE52</accession>
    <name>A0A1Y4DE52_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57403">
        <property type="protein sequence ID" value="OUO57403"/>
        <property type="gene ID" value="B5F75_01115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="106"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="229" mass="25038" checksum="2325ACD2248632B6" modified="2017-08-30" version="1">MAKNSKPSYIGHRERIREKFASAGLDAFLDHETLELLLTYAVARKDTKPIAWALLKKFGSLSAVLDADPEQLMTVPGVGPNTAQFLKLIRAVFKKYSFEEVKERITIRTPQQVLEYCKASLAGKTEECLEVIYLSVRNTVMSTQVVASGLIDRVAVSPRKIVECALAAKASAIILVHNHPSGDATPSKEDIALTQDVIRAAELFGISVHDHIIVGKGSHYSLKANGKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE70</accession>
    <name>A0A1Y4DE70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56952">
        <property type="protein sequence ID" value="OUO56952"/>
        <property type="gene ID" value="B5F75_03655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="414" mass="45402" checksum="28255FBC342D329C" modified="2017-08-30" version="1">MQTKTRRSMIIIAIANGLLLFGYGLSLPFFTIYLISQRGLTSSMAGLVIALAGLSRCVSSGISGELADVFGRKTVMVWGLFSQIVAMFALGLCIELKVQVGWMLACYFLTTFLGAFFRPASNAWVTDNTTPKERVEAFGIIRIGLNIGWALGPAAGGFLVRYSYSMAFFFTALLYAVTILYLNRQVQDNHTPCKSRKPSFVSALLSLKDSRLAKICFYVVVITAVNSQLVVGLSIHCKQYLHMPEYYIGWFFTINGLVVVFLQYWATRLMAKIRLSTAMFIGCALYAVGFGSVGFFDGFTLIALGVFLAGLGELIVSPGEQTLVSNIASRETRGRYLGMLMVFYNLGSAAGFFGAGLLSDYVAPHYLPGPWLIVGAAALLAGWGFWRMRRSLTDEEDGKTNVPVPIKKDTITLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE72</accession>
    <name>A0A1Y4DE72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57424">
        <property type="protein sequence ID" value="OUO57424"/>
        <property type="gene ID" value="B5F75_01230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="3">
        <location>
            <begin position="513"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="776" mass="83615" checksum="FEE3686902BDDB82" modified="2017-08-30" version="1">MKKWLRRAALAAVSALILFFGADLMLRWGSGWDWTRGWTVEKAAALLNREVRLEKMSASFMGVKLDGLEISEAGGFKNGTFLSLDRVRLRADLLYLLRGDFKVRSLTVNGAQIHLERLADGTFNWQSMVTSAPAAAAEKTESFQVPLDITLGQLTVQHLQLDYSDAQTHTRAAAKEVLFMVRHFAFGKPVAVRFRSTLLYEKDGQVFTLPAELKAEVLLKDLNLANASVNITDFSAQYQDAQLQLQLQADSLVQPAVAAKVQLQNLSAQALADLLPQVPPFAISQAEVNTRFRLTPAEQQLAVTDFDFSMPGVQAQFAGNVRYGDKPAYEVDSSFEIDAAQAAALFPPWEKQYRPSGLLKGTGSWNKEGAQAQLALEDGSVQIEHMGKFTGVTLAFSAQENAAFTQGSAKGTFNGKLNGEKFEGKLDVTQQPQQIDADLQLRAGRVALPPMAAAVEPPQTPDGFVADTQLVAAPEEAWPLPPVNIRADIQVASLDAPYVYGTDLVFRSDLTGVTPDLKQTHGDLTLSMGSGEIKDLYRLTNANAVTKVLFLSINIVGKVFNSMNVFAVLDGLGSGLLNVMGAGEPEEEGEADLVVKTVTGPDGQPMQIMVPYTDRKIDGRLAYDKFATSVQFTQGVADVHGGTFVSDMVSFTLDGKTDFNTGELDMTVQAAPGKHEEDGIMPLTVKVGGTVSEPKGSMSLIGSVSSLLTQGINNNFASRSVKKGIGGLFGLFKKKPAPQQTTAVTAAEPETAAQEQAASEQTPETTEAPETPEATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE83</accession>
    <name>A0A1Y4DE83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="8" type="ORF">B5F75_00810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57346">
        <property type="protein sequence ID" value="OUO57346"/>
        <property type="gene ID" value="B5F75_00810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="68"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="353"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="253"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="97"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="455" mass="50009" checksum="E97D215118532817" modified="2017-08-30" version="1">MKFKTVFVCQKCGYESPKWAGKCPDCGEWNTLVEEVKQQESKKAPARTRSFTDFSSEVVKLSESKSVQEPRIQTHIPEFDRLLGGGLVRGQLTLLAGAPGIGKSTLMLQVAAELSKTLKVLYISGEESIGQISGRARRLQVQGENIFLLCETDIQKIVESVEQVNPEVLILDSIQTVYHPEFTSSAGTVAQVRECTSELVRLCKPKGIITFVLGHVTKDGELAGPKILEHMVDCVLYFDTEKDNVLRLLRPHKNRFGSTSEIGLFKMTSAGLESVENASEYFAQTSRDRALKGRAYSLAAEGSRPLLTEVQALVSPTRYPFPRRVATGVDLNRCLMLFAALEKHIGLPLDNKDIFVSLTGGVKLKDPALDLAVCAAVISSCRDIPIAPDSVFMAEVGILGQVAKVPLLDRRLEEAQRLGFKKAFCAPVSKTEKQKLQTLSLCELADLNALALKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE4</accession>
    <name>A0A1Y4DEE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="10">ATP-PFK</shortName>
            <shortName evidence="10">Phosphofructokinase</shortName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pfkA</name>
        <name evidence="12" type="ORF">B5F75_01355</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57447">
        <property type="protein sequence ID" value="OUO57447"/>
        <property type="gene ID" value="B5F75_01355"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="5"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="139"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="183"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="286"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="116"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="10">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="366" mass="39125" checksum="673DD4B5B1FBE5DA" modified="2017-08-30" version="1">MSIKRIGILTAGGDCPGLNAVVRAVSKNALKNGIEVLGFKNGFDGLVRNEFLNITNETVSGILTMGGTILGTSNIANPFNYTLPPFGSADSPRDLSSVALHNFKENQLDALITIGGDGTLHMSQQFVDLGLPIVAVPKTIDNDLSATDQTFGFDSALAVATEAIDRLHTTAQSHHRVMIVETMGRYAGWIALRSAIAGGGDIVLIPEIPYNEDVIVNYILDRKAKGKNFSIVVAAEGAKNELGEQTVARTLPGSTDPIRLGGIAYKLSNMIEDRTKIESRACVLGHTQRGGTPTAFDRWLSTLYGAKALDMVLQGQFGYMAAFRDFKITEVKIADAISNLKRVDPHGEEVKAALEVGMSFGSSEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE5</accession>
    <name>A0A1Y4DEE5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">B5F75_01805</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57533">
        <property type="protein sequence ID" value="OUO57533"/>
        <property type="gene ID" value="B5F75_01805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="288"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="461"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="613" mass="67102" checksum="4695441EEF9C4381" modified="2017-08-30" version="1">MCGIIGYVGNNNSVPYIIDGLKRLEYRGYDSAGISILQGHELVTVRAVGKVAELEKATLLANPKGNTGIGHTRWATHGKPSEENSHPHTDCTGDIVVVHNGIIENYLTLRDKLESRGHRFKSETDTEVIAHLIEENLLHVRAENDQDRLLKAVQKTNKEIAGAYAYGVLWARTPGLLIGVKNQSPMVVGLGKDENFLASDVPAFLKHTNKVLFLEDGEIALLHVDGVTVLDKDGKEKEVKPVKISWDQQTAEKGGFAHFMLKEIYDQPQAIEDTLRTARADFGKILGLDTTGIRELRNIHIIACGTAYHAGLVGKYYIEQLAGIPVSVDLASEYKYRAIPPLPHTLAVAISQSGETADTIGAIKKAKELGFRTLAICNVLGSTLTRTCDGTFFTHCGPEISVASTKAFTSQITSVYALALFLGKANGNLSQAAFDKAYKGLLALSKAMSEAVKLEYEVRHLTRKIYKADRFIFLGRNVNFPIALEGALKLKEVSYRSAEGFAAGEIKHGPISIIDKGTPVFMIMPHDSLFEKMLSACQECRARGAFVVVITTKNGVKQAKDVADKVITVPQTDDLLQPIIDVVPLQFLAYWIAKRLGCDIDQPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF6</accession>
    <name>A0A1Y4DEF6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57022">
        <property type="protein sequence ID" value="OUO57022"/>
        <property type="gene ID" value="B5F75_04030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="15669" checksum="A1928CBFA80B3877" modified="2017-08-30" version="1">MAAVLRPEDRAELAASHPAQEPQELLVHFFKRSSACFVLEYEGEPAALFGVAPDVWMGRRACVWLLTGRRVRRIAKTFVRVARALLAGALRRYEELYNFADGRYAAALRFIRRLGGTFDGTVCQTGCAPFLRFTFRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF8</accession>
    <name>A0A1Y4DEF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57467">
        <property type="protein sequence ID" value="OUO57467"/>
        <property type="gene ID" value="B5F75_01455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012443">
        <property type="entry name" value="DUF1646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07854">
        <property type="entry name" value="DUF1646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="353" mass="38708" checksum="BBBBDB53E075B6FE" modified="2017-08-30" version="1">MEIAAVTPWWVNVLLGIVVVNLLVWPLTSRWVESHLELFLLGVGAAAVTISGGWSTEFLYETLNYPVNVAFIVLVVSVIFNNYSRYIFRVLFAFFRKLEPRYSFALLIFFLGMTSSLVSVTVSALVLAEVLKVVNLERTATVRITVFACYAIGLGAILTPLAEPLGLIINNALAGAPHHADFFFLLRHFFWWITPAVVLLSLAAGYCARNAGTTLQMHIREDKETYASMLRRTLHIYMFVAALNLISTGLRPLAQSTITHLGGKILFLANAVSVIIDNTTLAAIEIVPSISDKDLIYMVIGLAAFGSMLVQGNLPNIVAAEKLGIKSREWASIAVPTGLVLMAGYFLSLSILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ0</accession>
    <name>A0A1Y4DEJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57315">
        <property type="protein sequence ID" value="OUO57315"/>
        <property type="gene ID" value="B5F75_00630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="90"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="333" mass="36960" checksum="C5232A551C6D128C" modified="2017-08-30" version="1">MTLWQILVSYSLLVAASLSLLTYWITKKFVLKKMHRTIMKAEHNYQQQIATLQMQLSGKVNVLESMVEKLRLSNQELNRLNEIRAKFMSIVAHDLRQPLSSIQGFTSVLMMDNPQGGGNNDQTALNNILKATDNMNMLMADLMDISMIESGRFKMDAQPFNFNALLNDVITLQAVNAQKKGIFLQKCEYPAEVTVVADRFRISQVLNNLIGNAIKFSPQGGSVEARFYVLNGMLTFKVADNGPGLLHTEKDKVFQKFHQSENDRTLKKQGWGLGLSIAQEIVNAHGGEIGVESAGLGQGSVFWFSIPQTPAAAAADADKAPIPNVEKKTVMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK9</accession>
    <name>A0A1Y4DEK9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication-associated recombination protein RarA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57603">
        <property type="protein sequence ID" value="OUO57603"/>
        <property type="gene ID" value="B5F75_02180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="44"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="417" mass="46363" checksum="9DB061D54A26749D" modified="2017-08-30" version="1">MTPDEQENIPLAARQAPKRLEDFAGQPHLLGPGKMLRRLLEADMIKSAVFFGPPGCGKTATARYIASRTQAYTVELNAAAAGVADIKKVLAEARERARTPTFDQKRTLVILDEIHHFNKTQQDVLLPSVERGDIILIGITTENPYFYINTALLSRFSVFEFKALGEKDLLKILNRAAEKEKAQIAADAADYFITQANGDSRKMLNAAELAFVTTPPAQDGLKHIDLDIAKECIQRRHLNYDKKGDEHYDIISAFIKSMRGSDPDAAVYWLARMLESGEDPRFIARRILICACEDVGLAEPYAIMIAQAAFAAAEELGMPEVRIPLAHAAIYVACCPKSNSAYLAVDAALTEVREGKYRPVPDHLRSGGKNRGYKYAHDFPNHYVKQLYMPSPMQFFKPGVLGKEAAIIERLKKIKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM7</accession>
    <name>A0A1Y4DEM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57547">
        <property type="protein sequence ID" value="OUO57547"/>
        <property type="gene ID" value="B5F75_01880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="19278" checksum="CAAC1B9F4C837622" modified="2017-08-30" version="1">MKKGFTLIELLVVVLIIGILAAVAMPQYTLAVEKARSAEAFETMKSLGDAMELYRLQNGGDMSAFTSSTDRWGLLDIDFPLPASGHTNAQTLGLKESKNFTYSLESPNFVRAYRGTAQGNQWTNHDYDLFLDLNGEQWSFSKKGYRLCGAVTTQGQKICRSMGTLLSGDKYLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN5</accession>
    <name>A0A1Y4DEN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable endonuclease 4</fullName>
            <ecNumber evidence="7">3.1.21.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Endodeoxyribonuclease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Endonuclease IV</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nfo</name>
        <name evidence="9" type="ORF">B5F75_01935</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.21.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 3 Zn(2+) ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57557">
        <property type="protein sequence ID" value="OUO57557"/>
        <property type="gene ID" value="B5F75_01935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="8">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="276" mass="30437" checksum="E9625667529C824C" modified="2017-08-30" version="1">MFYIGCHLSASKGWEAMGKTALEINANTFQFFTRNPRGSKAKELDLQDVARLRQLLVQHRFGPVIAHAPYTLNPAAADPHIRTFARQTLADDLARLEHLPGNLYNFHPGSHVGQGTEAGIRLIIQTLNDILSPRQHTTVLLETMAGKGSEIGRSFDELKQILDGVKQNDKLGVCLDTCHVHDAGYSLAVLDGMLEEFDKQIGLPRLKAVHLNDSLNPRGAHKDRHAPIGQGEIGTQTLARVINHPALKDLPFCLETPNDLAGYAREIALLRSLRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET1</accession>
    <name>A0A1Y4DET1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ORF">B5F75_06320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56229">
        <property type="protein sequence ID" value="OUO56229"/>
        <property type="gene ID" value="B5F75_06320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="64" mass="6892" checksum="6A9A5F962AE2D3A6" modified="2017-08-30" version="1">MAYKCAVCGKAPVSGGSYSHSNLRTKRSFKPNLQKQKVVLDGKTQTAYVCTGCIKSGLAKRPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEZ3</accession>
    <name>A0A1Y4DEZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Peptidase_M50 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">B5F75_00065</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57212">
        <property type="protein sequence ID" value="OUO57212"/>
        <property type="gene ID" value="B5F75_00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="15">
        <location>
            <begin position="126"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OUO57212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="211" mass="23190" checksum="7357FB85EA8DF226" modified="2017-08-30" version="1">MEVIVFLPILFFSIVLHEFAHGLAAYRLGDDTAYLSGRLTLNPLHHIDPIGTLAVPALCWLIGMPLFGWAKPVPINPMRMPSPRRDMGKVAFAGPAVNLLLAVVCVLVMKILLVGQAFFSARALEQLFLFLQYGMFINVFLAVFNLIPIPPLDGGRIVTALLPLQAALKYDGFFGRYGMYVVLALILTGAVKYILLPPTMLVVGAFSKFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF48</accession>
    <name>A0A1Y4DF48_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57716">
        <property type="protein sequence ID" value="OUO57716"/>
        <property type="gene ID" value="B5F75_02390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="6">
        <location>
            <begin position="6"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="223" mass="26138" checksum="AE301454872D3F9F" modified="2017-08-30" version="1">MKADLEWSNTVYFAGFVAAFVMFFFIQAFKIPSASMHNTLLEGDHLFVNKAAYGFRIPLTNIRFGQFEEIKPGDIIVFRFPAKDRQQQNCGGSQYGKDFVKRVIAMPGDTVQVINGRPWVNGKELPQQDYELYEDIERTPYFAEEDKAHYQQVWEEHQLDNYLGLYLRDSFGPVTVPENTYFVMGDNRDNSCDSRFWGPVPRENIKGKAWFIHWPLNRVRWIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFC2</accession>
    <name>A0A1Y4DFC2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57342">
        <property type="protein sequence ID" value="OUO57342"/>
        <property type="gene ID" value="B5F75_00780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="457" mass="49162" checksum="23ECF560EDAC04A0" modified="2017-08-30" version="1">MLNEHKNNVISIIKWFLLASAVGCVVGVLDAAFLKILDRAISFRNGIPLFYILLPFVLYGVALLGRKVAKRHTDYSTDAVINKINSYRSISFISIFKGFTLSIVTMVMGGSAGKEAPCADVGAGVSSILARWVRMSPQDQRKMMICGVSAGFAGVFGVPISGALFGLEVLWAGHIFYEVMFPALVAGITAFQVTSFLGVDYIYHPLHFVPVFSEQFFLKMIIAGMFFGLISILFIEITKFTRVLFRYIALKTRLFWACVTGGLLLVAVGYFISPLYLGLGMPGIESVLGGAAPESPFGFLYKMITTSVTFAAGGIGGVVTPIFFVGAQAGAMLADFLRVDSATLAALGLVAVLAGTANTPLSASIMAIELFGADIAPYATVACVISFLVTGQQSIYPSQRISLEGGKTGDAPDASSSNYDTPLRPAKIPYRKTMFKQAFKKMVKHLIPNPKGFDDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFH6</accession>
    <name>A0A1Y4DFH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57685">
        <property type="protein sequence ID" value="OUO57685"/>
        <property type="gene ID" value="B5F75_02615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="21370" checksum="5409A57D9C66327D" modified="2017-08-30" version="1">MEETKVPLKKVEKVIGLETVPSTQDLALELARSGEAEGTLVLACEQTAARRLDGSRFHAPEGGIYFTLILRPQRADLCALSLSRQTAQALADALAAVFDLKTKVKDGHSILAWDKKNRKWKKTAGVLAETFFEENGRFALVGVGVNVNNRVPAGKEPHLSLKQCAGTEISKELLLDELLTAFWKQYAYWLKSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFK0</accession>
    <name>A0A1Y4DFK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57422">
        <property type="protein sequence ID" value="OUO57422"/>
        <property type="gene ID" value="B5F75_01220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="451" mass="51203" checksum="8436CD41FD4D771A" modified="2017-08-30" version="1">MSKNLSQLLRGSFTAPRMVLENGALSSAQKHLLESQLTALEETRRALVQNPGWAVSKDFNLTAKRLARLELPVPPKPKADAPTAEKERYLKRLNKLLYRESKALASVLDQQPRPYTPDKRLNWEPLSTPRQQALTRDHWEQILASGNPSFTWGTQNWDEVQVNPLRFATNPNDPDYIPEEAWEELTWETGSSKYEFYNAILDAPALTSRQKQLLICAAEEASAVLTYEFVQLYVPAFGMLPQAVVPSAAEPDAHAGLEAYATAVQKKLLLKLQDEGSWSPADFERFAQVSVFLPAEKAQAVLGAATFLETQAPLWLLEHPLDHPLSQEILKRTQDARLHQQERWPDGVILPKAKLSNRFKLLYSARRKALQAYSDLLWNRLQKLLDKQDSARRAAQILTDHPPTKDSTVEDKKQILATWIFISAREARLQKNINEVSLRLHQTEAELGRMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG44</accession>
    <name>A0A1Y4DG44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA polymerase I</fullName>
            <ecNumber evidence="7">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">polA</name>
        <name evidence="10" type="ORF">B5F75_05410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56629">
        <property type="protein sequence ID" value="OUO56629"/>
        <property type="gene ID" value="B5F75_05410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="8">
        <location>
            <begin position="5"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="9">
        <location>
            <begin position="614"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="858" mass="95697" checksum="FBCFEDAFD6452A08" modified="2017-08-30" version="1">MNNFSPQFFLIDAHGFLHRNYHALPKLSTSSGQEVGALYGFVRWLIKMLREQNPAYVAVCFDSPGGCARRKALLPSYKANRKKPDDALVSQLNLARELVDTLGLKVVAQDGIEADDLMAFLALSAAKQQVPSVLVTSDKDVYQFLNDWIHIWPSGGKDGFKGPEAAQEKFGVDVPFLPDYFSIVGDAADNIPGVMGVGPKSAVELIHKFGHLEDIIRAAQNDNPDLKPALAKKILAHEGEALLSKQLVVLDPNLQMPFSLEDYRVRTPDAEKLSALFAHYEFKNLLDFFQAPRPAAAVVAQETRVEMSLQDVLNRAGQSGAVFVHTQDDFLAVGLNAREAAVVPLSEVEPWELDALKKIIENDAVEKIGYDLKLTLRELDINVHGQFISCFDGRLAKYLLDPSGDLSFSGACLEYFSATVSEEDPRALLWEYNRFIWPLKEQLTQKLQQSGQYELYRTLELPLMMVLSDMEFAGFRIDPGWLESFKALLEQEIARLQKEIDGYAGYPVNINSTKQLGTLLFEEMKIPPVKKTKTGYSTDEAVLEQIAQTHPIARAILEYRANNKLKSTYVDNLLLMADENDKVHSYLDQTGTVTGRLSSSSPNLQNIPVRTEKGRLLRKAFCAAPGNVLLSVDYSQIDLRVLAHESQDPVLMQAFWDGGDIHTQTAAQIFGVMPLMVTDQMRSSAKAINFGIIYGQGPMGLSQSLGISMREAKEYIDNYFKNFRVVREWIDKNIAAARQNGYVKTMLGHVRYLPEFNMGVGAMASFAQRAAINTIVQGGSADIIKKAMIDVFTAYRGTPVQMTMQVHDELIFELPQQQLTEAAAHIKELMQNAVHLRVPLLASAKAGKNWYELEKLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG82</accession>
    <name>A0A1Y4DG82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56669">
        <property type="protein sequence ID" value="OUO56669"/>
        <property type="gene ID" value="B5F75_05615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="178" mass="20004" checksum="DA447B92309B82FC" modified="2017-08-30" version="1">MPRKKATEKAETQNQPQQDEIETALESRNLFHHFTEEELAGLNEKVTDLTEKKNAFAEKAKLMGDIAKGSEAEIRHTIGLIKEGGEERTLECPVIINYTQNTYTVKHPETGDVLDQRPLTAKEKQRELFPQQGEGAPVQEETEQTQSQEAQAQEAQAQEFDPNLGAAEPQEGEDDLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGP4</accession>
    <name>A0A1Y4DGP4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56839">
        <property type="protein sequence ID" value="OUO56839"/>
        <property type="gene ID" value="B5F75_03055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="11337" checksum="573C4551CBD8249E" modified="2017-08-30" version="1">MSVKNDKEFDAKLMNFDGDRYDVVVLASIWAKELKKKDEYKNQPNAVVIKVALDDILSNRVSKDEVLRISKENLEAELKAQEEARKEAERKAKEPMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH12</accession>
    <name>A0A1Y4DH12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56969">
        <property type="protein sequence ID" value="OUO56969"/>
        <property type="gene ID" value="B5F75_03740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="3">
        <location>
            <begin position="112"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="450" mass="51439" checksum="0F7A77EDB243014A" modified="2017-08-30" version="1">MTIQRNAEEKEKIKEILALAERNNIQIIKLWFVDILGNLKSLSLSYREFEYAMNEGMGFDGSSVEGFARLYESDLVALPDLDTFQMFPPEFTGAPIARFFCDIKTTDGKQFEGDPRYILKKNLAEMKKAGFDQFMVGPELEYFYFKDNKHPETLDCGGYFDTIPLDSSYAVRRQTMQMLEKLGIHVEYSHHEVAPSQHEIDLRYDEAMKMADQVITYRTVVKQVAAANGIYATFMPKPLAHVNGSGMHVHQSLFANGSNAFFDEKDPLYLSQTARHYIAGILANVKEICSVTDQWVNSYKRLVPGFEAPAYIAWGRKNRSALVRIPQAKQGKANATRIECRFPDPACNPYLAFAVMLGAGLDGIKRKLQVPPITEENIFHMTPQERKAHGIDTLPAYLYEAVNYTRHSKLVRQVLGDHTFEKFIANKDIEWDNYRTHVSSYELEKYLSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH44</accession>
    <name>A0A1Y4DH44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56999">
        <property type="protein sequence ID" value="OUO56999"/>
        <property type="gene ID" value="B5F75_03890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="410" mass="46427" checksum="8F524CBED5FFDEB5" modified="2017-08-30" version="1">MEKTKILYFITRMDQGGAQASVLTTIKTINKQQFETYLATGPGGRLDGRFKNDTQHVFFITALRHDIRAKYFFHDLVALFQMGRILRRVKPDIVHTNAPKAGVLGRIAARIFWRKAKVVHTFHGLGFAKEHGEKQFKFFVAVEKFCAKFTDVLVFVSRRNAAEAKQLGIGKGVRTELIRAGVNFNPILPLKFDPVAKKASLKIPANAKVVLALANFKPLKNPIHFVLAAYKVLSQMKNVYFIFTGDGPLKETAVNLAKNLSIEKQVIFPGWRNDALELLAICDVYASVSLREGLPMSLLEAMSMRVPAVCYDVDGIGEVITNNKTGFLVAPNDINTFADKLKVLLRHASLRERFEAAIDHRDFSEFTASTMVKKQERLYRSLVPPTKKNGGKRRFFRRRRHFKKFNPGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHA2</accession>
    <name>A0A1Y4DHA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56308">
        <property type="protein sequence ID" value="OUO56308"/>
        <property type="gene ID" value="B5F75_06750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="232" mass="25862" checksum="A6E30A5292D7AD90" modified="2017-08-30" version="1">MDILLASPQLDVFEQMALDETLVRVHPQAVTLRFYRWTPGPAVTFGYAQFISEVRRTLAQRRFSGPAARRPTGGGIVFHEDDLTFSLVFEAPGRPADIYKNFHAHIHAQLNRLGEKGEIFDKTLPASAYAPSVNHTASACFSNPVENDLLAANGHKILGGALRRFGTTVLYQGSLQLPQARENPAYKNAIIAAVRAYLAADLHPHRATEEWVLQAKELARAQYHTQAWTEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHG0</accession>
    <name>A0A1Y4DHG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Zinc transporter ZupT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">zupT</name>
        <name evidence="13" type="ORF">B5F75_05865</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mediates zinc uptake. May also transport other divalent cations.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56358">
        <property type="protein sequence ID" value="OUO56358"/>
        <property type="gene ID" value="B5F75_05865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00548">
        <property type="entry name" value="ZupT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023498">
        <property type="entry name" value="Zn_transptr_ZupT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 12" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="257" mass="27028" checksum="ADF517D98D1C51D8" modified="2017-08-30" version="1">MEQSILTAFTLSFLAGAATAVGGALAFVIKRENLSVLSLGLGFSAGVMIYVSFMEILPQATQALGLLFGEKPGAWAATGLFFAGIVLAWLIDTLLPSHHLEQHTLDQSAKLKHLGLFTALALAIHNFPEGLATFMASMQDATLGVSIAVAVAIHNIPEGIAVALPVFHATGNRKQAFWYSAGSGMAEPVGAVLGFFLLKSVLQETAFGVLFGLIAGIMVYIALDELLPTAHEYGDGHKVIWGVVGGMMVMAVSLLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIB1</accession>
    <name>A0A1Y4DIB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56678">
        <property type="protein sequence ID" value="OUO56678"/>
        <property type="gene ID" value="B5F75_04425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="362" mass="41072" checksum="6B54160AF380D79A" modified="2017-08-30" version="1">MQHTSDGLSTQGIKYAGSKKKLLPYLLALAAELPGVQTVLDGFSGTTRVAQALARRGYTVTANDTADWSEVFATCYLLSSRPDSFYAPLLAHLNSLPGQNGWFSRHYGGKETDAKKPFRLKNMQKLDAIRAEIDRMPLAWPDKCVLLSSLMLALDKVDSTLGHFCSYLSRWSARSAGDLTLHLPHRFAHGGGHRVWKQDIFQAAARQNWDLAYFDPPYGSNNVKMPSSRVRYAAYYHFWTTLIRNDRPELFGAAARRTDSRDRQAGSVFEDFRRAPDGHLWALHALQKLLAQTQARYIMLSYSSAGSIAKEDLLDALRQNGKLLKFLKIDYKKNIMSEMSWTGKWTRDEKNYEYIFLIQKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DID5</accession>
    <name>A0A1Y4DID5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57419">
        <property type="protein sequence ID" value="OUO57419"/>
        <property type="gene ID" value="B5F75_01205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="187" mass="21512" checksum="6196E0D29686D71F" modified="2017-08-30" version="1">MNGIWIVILILAVFGVYAMMTYNKFILLKNRVTEAWSDIEVQMKRRYDLIPNLVETVKGYAKHESGTLEKVIQARNIAMAAQGNMKELSQSESMLTGALKSIFALSENYPDLKANANFMELQRELRDTEDKLQAARRFYNGNVLALNTKIELFPSNIIASMFHFEKRDFFELAEEEQDARSAVKVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIF1</accession>
    <name>A0A1Y4DIF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57439">
        <property type="protein sequence ID" value="OUO57439"/>
        <property type="gene ID" value="B5F75_01315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="437" mass="48410" checksum="C80E5A21EEECE5D5" modified="2017-08-30" version="1">MKKLIFLFSLFVWAGAPVGAQPMQQVVGEVRASAARMSGKTLQKRFLLKPGDPFTPALFDKAQDDLHDLRVFKKLEFSTQEKNGKTDIFINAQDGYYIFPLAFASGGKKNAAALSLAAGNLFKQGESTFVFAGGSDDGFTAMAGLSLGDDFISLGFTKLNFDQRFYQNGWSNTFGVFSTTDDEDEYHSSLLGALHTRKEQLALTYMHRFSRTLRAFVRPEYVRYTYSPRALDNGSHNQITLGLRLSDDVRKGVNMGALSGYGLTDKKKSLQNLPRPRTGYAANVFYTAGGSWTGSDYEISKLGLEAAGLLEFKNRHMLVAEIRAQDAFKAPFSDRVLSSELLSGLGRYDRQIRGSRGAGAAVSFIYYLLRNETGLLSLAPFYELAYVYAGSRYRPHSGAGAALTYKLWRFPFPFGINYTRNLQDGSDTVGFVFGGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIP8</accession>
    <name>A0A1Y4DIP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">L-lactate dehydrogenase</fullName>
            <shortName evidence="6">L-LDH</shortName>
            <ecNumber evidence="4 6">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ldh</name>
        <name evidence="12" type="ORF">B5F75_02895</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of lactate to pyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(S)-lactate + NAD(+) = H(+) + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="4 6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56808">
        <property type="protein sequence ID" value="OUO56808"/>
        <property type="gene ID" value="B5F75_02895"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00554">
        <property type="reaction ID" value="UER00611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00488">
        <property type="entry name" value="Lactate_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011304">
        <property type="entry name" value="L-lactate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018177">
        <property type="entry name" value="L-lactate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01771">
        <property type="entry name" value="L-LDH-NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00064">
        <property type="entry name" value="L_LDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="10">
        <location>
            <begin position="10"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="11">
        <location>
            <begin position="150"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>beta-D-fructose 1,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>beta-D-fructose 1,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphotyrosine" evidence="6">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="318" mass="34550" checksum="83217CBCF3CFD8C1" modified="2017-08-30" version="1">MEQNFVNFNKVGIIGCGFVGAASAFSLMQSGLFTEMVLIDSDQARAEGEALDISHGIPFAKPMEIYAGNYDDLKDAGLIIITAGANQKPGETRLDLVKKNIAIFKSIIPEITKRDFKGILLIVANPVDILTSVALKLSGYAPNRVLGSGTVLDTARLKYNLGQHLNVDSRSVHAFIIGEHGDSEIAAWSCANVSGIKLDKFCEMRGHFNHQEATRKIAEDVKNSAYEIIARKKATYYGIAMSVKRICEAIVRDEKSILPISAQMNGEYGISGVALSLPAIVNSQGVETHVPLQLNEEEVSALKKSADTLKKILEENQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIS1</accession>
    <name>A0A1Y4DIS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56210">
        <property type="protein sequence ID" value="OUO56210"/>
        <property type="gene ID" value="B5F75_06220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="32674" checksum="9CD43F012BDDD650" modified="2017-08-30" version="1">MKKHLPAVLFLLAAALIWWLSLAPRRHQVPVAEGAKPRVVTSGYVPYTLAKQLSGGLADVTMLLPANAEPHSFEPTPGALVTVKNADIFIYVSDRIEPWAKDVLSSAGEQTAVVQAAKYAASSDDPHVWMDFQNAKQIARAISFALVQKDPSHRAEYEAHLKAFEKELAELDAAYQTGLASCQSRQVVHVGHLAFGNLTKNYGLSLSALAGSSHDGENSVRRVAELIRFIKDNQIRAIFTEETLSPRLSAAVAEETGAQVLPLYTVEHVSKDDFDRGVTYGELMRRNLDSLQRGLGCQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIT9</accession>
    <name>A0A1Y4DIT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NifU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57589">
        <property type="protein sequence ID" value="OUO57589"/>
        <property type="gene ID" value="B5F75_02100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="1">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="74" mass="7935" checksum="9A8D937A4F6E9A2B" modified="2017-08-30" version="1">MKEQVQDVVNQIRPILQADGGDIELIGVDEKTGIVTVGLRGRCGGCPHAQMTLQAVVEKKIKELVPGVTAVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIZ8</accession>
    <name>A0A1Y4DIZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57639">
        <property type="protein sequence ID" value="OUO57639"/>
        <property type="gene ID" value="B5F75_02360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012802515" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="5"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="211" mass="23237" checksum="831AB256154B5E18" modified="2017-08-30" version="1">MKKLLLLCALCLAVPAAAQEYYGLQEYGLRKNTTRIEFYGGMVLPQDSWFHNGQEVDLGGTGWTAGLGFVRNITPVFALGVDANYAQPGDGDNFTSGGQNAYYRTGIATGLVTGRINFFPSQSTRLYIPVGIGVGHMFARQKNEDGSHLTTDSTDLATMLGLGLEFDIDETVIFGVEGRYYYLDANDEFHDALGKGHYHYLTVMLKFGTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ28</accession>
    <name>A0A1Y4DJ28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56320">
        <property type="protein sequence ID" value="OUO56320"/>
        <property type="gene ID" value="B5F75_06815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="447" mass="49548" checksum="0EE2D2A24690EFDA" modified="2017-08-30" version="1">MAAFRNFTLRSGRSRLDYILFGAMIALVVLGALCIMSAVNSLSFSNPVVRTHLVALPIGALAFFVGWSFNYQIFDEQWKYLYGFILALLIGVLLFGSYQRGSRSWFVFPFFSMQPSEICRVCTILVAAAYLDRRGQRIRDVSSLFGLGLLLLPIFGLIMMQPDFSSVVVTLPALLVLLFCTGVNVFYLGLIGLFVGVVGVFTVGWTYIYLHPELLDYWIVNAFYQLAHSPWYMAGFSVLVMLGGYGAWWFFKQLRIFLPSFYFVVATLVVLAGLFGGIVVDHQMKPHQRKRVETFLAPRSDPQGAGYNVLQAQIAMGAGGILGTGLFSGTQSRLGFVPEKHTDFILAVVGEELGLWGTLMVLGLYLLILWRTIVVAYSASDRYGYLVCAGIFGMFFTYMLVNFGMLIGIVPVAGIPLPFISYGGSNLVASLWALGVVQSVYARRIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ34</accession>
    <name>A0A1Y4DJ34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">anmK</name>
        <name evidence="2" type="ORF">B5F75_02580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57679">
        <property type="protein sequence ID" value="OUO57679"/>
        <property type="gene ID" value="B5F75_02580"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="362" mass="39612" checksum="3E097BEB1F33D82F" modified="2017-08-30" version="1">MAKFALGLMSGTSADGLTVSAVQLRPLRILHFKNYPYPSRLQQKLLTAYALPAAELSALHFELGKLYAKTVQKFLKEFHLSAADLEVTGSHGQTIYHGPYDAVPNTLQIGEPSFIAVQTGRPVVSDFRPMDMALGGQGAPLIPFFDAYVWGRGTPKILLNVGGISNFSVVGKNIKTFGFDVGPGNTLLDLAAQRLLKQPFDKNGRTAARGTPDVKRVQILLRQKYFLQKPPKSLDKNTFGEKYLDRYFPRADFKSTADLLATLTWFTAAAVAQAVQQFVPAACRRELVVSGGGCYNHTLLAFLRRLLPALKITTTLSYGIDPQAKESAAFALFAWRALHGQINHCSRATGARKDAVLGKITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ78</accession>
    <name>A0A1Y4DJ78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56360">
        <property type="protein sequence ID" value="OUO56360"/>
        <property type="gene ID" value="B5F75_05920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12682">
        <property type="entry name" value="Flavodoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="41"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="195" mass="21056" checksum="AEA17238EF0B0B16" modified="2017-08-30" version="1">MTRLFYSGLIVLSAAACRADTPDTGTSSAGAVQNPFAGKKVLVAYYSHSGNTQAVARQIAQAAQGDLFAIETVQPYPAAYNDLTAQAKREINAGFMPELKNKVPQMETYDVVFIGSPNWWGTYAPAVKTFLSQYDFSAKTLVPFFTHGGGGMQRCESDMKAQLPQARFLKAASFPGRSSGASPEALQNWLDKLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJU8</accession>
    <name>A0A1Y4DJU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein B5F75_05310</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56610">
        <property type="protein sequence ID" value="OUO56610"/>
        <property type="gene ID" value="B5F75_05310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="252" mass="27161" checksum="F0423C0D240E2DA2" modified="2017-08-30" version="1">MGGHSHWAGIKHKKALVDAKKGKVFTKILREITIAAKMSGGNPDQNPRLRKAMDDARAANMPSDNVKRAIMKGTGQLPGVSYEEITYEGYGPGSVAVIVECTTDNKNRTFSEIRKIFTSHGGSIGTAGCVSYMFKGKGLIVVKKEDISEDDLMNLALEAGAEDVRTAGDVYEVITSPDMAELDAVKKAIEAKGITPVSADLTMLPDTEVNITDEHTAETLMNMLEALDDHDDTKNVYDNSNIDEAVAAKLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJW9</accession>
    <name>A0A1Y4DJW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56630">
        <property type="protein sequence ID" value="OUO56630"/>
        <property type="gene ID" value="B5F75_05415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012915278" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="18"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="15928" checksum="B044DC9F26636343" modified="2017-08-30" version="1">MKKVILSVFVAVAVLACAQLGFAQQAGALPKLTSKAYASMKKDEVYVVLFSAPYCGGCHLAQQTLFPALMKKYASEKNVHFYVLDVEEDVAAADGTFLKDKWGILYLPTFVVAYNDAVMYFKSGYSDKMEAALTKEISTQVDSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKJ7</accession>
    <name>A0A1Y4DKJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57448">
        <property type="protein sequence ID" value="OUO57448"/>
        <property type="gene ID" value="B5F75_01360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="7"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="249" mass="27377" checksum="8665E33B82622331" modified="2017-08-30" version="1">MNDNLDMIYGIHPVMEALRSKKRNVTQLYVSDSKAGHRAVEEIIRLAKRQNVKIDRIDNKTLDRLTRNANHQGVMAKVQPIKLMKLSTALYESDGNKKDLWLAVDEMTDPQNLGAIIRSAACLGFSTIILPQRRTVGITPAVYKVACGAIENINIVEVANLSAALNDLKEEGFWVYGADMDGQPITQTDYASPAVLVIGSEGFGIREKTAENCDQIISIPQRGGVESLNASAAASIIMYDMMAKVQLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKK6</accession>
    <name>A0A1Y4DKK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57458">
        <property type="protein sequence ID" value="OUO57458"/>
        <property type="gene ID" value="B5F75_01410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012350577" evidence="1">
        <location>
            <begin position="19"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="432" mass="47704" checksum="7C58BB29C79DB24E" modified="2017-08-30" version="1">MKARICLLGLALVCSACAAPSLRYKTEINRLTAAGKFEQAAARVQEKKDKLYSRRDGVLFYLDSATLLHDAQDPSASDELFAQAQQEIDARYATSVSGTVGSLLINDLTAPYYTPAYEQALTYYYRAQNFLQQGDISSAAVEARKAVFFLDHLRADKKKGYNDDPFVQYFASLVFESVGQRSDARIARQNALNAYQRLGKQLHLEAPDFSVPANAGELCEVLVFHYNGRMPLKRTQTLQVAWSDALALASSPGETQQGVSPQVQNAIAAGWMGSAVTLSYPEWVEQPGRVAFSAVQAGQVQYPTQKVADFAAAAKLDLEEKMPGILFRTATRAVTKRVAAVQARHAAQDDTWGTLAEMFVSALGAASETADTRQWFTLPAEVRLARLFLQPGKQDITLLFRDGYGNIIGEYTFKDVELTRGGRVFLHYRTSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKN5</accession>
    <name>A0A1Y4DKN5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57488">
        <property type="protein sequence ID" value="OUO57488"/>
        <property type="gene ID" value="B5F75_01575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="21830" checksum="5A4732D3B51E60EE" modified="2017-08-30" version="1">MKNKDYSFYIYALKDGRKNPAQIFYIGKGTGMRKEEHLLNIDNTNKGQFIQEIIQDGGKVLVSTLIDNLTEQQALTLEAELIASFGTEKNGGILKNSVTPNPSITSSKRELNLPVGVYELATIGLDFMKKAILEFLEANPDGIKNAEFARYLNLHSDNAGKQKDYLTYSILGILMRENKIRKEPHGKYKINQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKQ3</accession>
    <name>A0A1Y4DKQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hydrophobe/amphiphile efflux-1 family RND transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01675</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57508">
        <property type="protein sequence ID" value="OUO57508"/>
        <property type="gene ID" value="B5F75_01675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="537"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="872"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="897"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="925"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="971"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1002"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="5">
        <location>
            <begin position="374"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1050" mass="112715" checksum="7424D990CA933266" modified="2017-08-30" version="1">MFSKFFINRPIFSTVISLLISLAGIVSITMLPIEQYPDLTPPTIEVSASYPGASPEVIANTVAAPIEQQVNGVEDMLYMNSTSSSNGDMSLVVSFKVGTDPDQAMINVNNRVQGATATLPEDVRRYGVEVNKKSSAILQLIALYSPNGHSDTTTIGNYALLNIVDDLKRIEGVGDAQVMSANDYSIRIWIKPDVLSQRGLSVSDIVAAVQAQNTQRSAGKIGQPPLPVEVDRMYSIVAPGRLTDPKEFEEIILRANPDGTSLRLKDVARVELGSQTYEFNGRFNGKPAVPVGVYLSPGANAVATAKAVDEHMKEIAQNFPPDLDIDYKVAYDTTLFVTASIEEVIHTLIEAMILVFLVVYLFLKDWRATLIPCLAVPVSIIGAFAGMLLLGFSINTLTLFGLVLAIGIVVDDAIVVIENVERIMHEENLPVKEATIKAMGEVSGPVVAIVLVLCSVFVPVAFMGGLTGIMYQQFAITIAVSVVISGLVALTLTPALCALLLRKQPHPTRGFFYQFDRFFEKLTAKYGTWVAFFIRKLTVSVVLIAVLFLGAFGLFKIVPGSLLPDEDQGVIMVAAQLDPSASLSNSDEVAVQLENLIMAQPAVSEVLTFSGYDILSSTQKSNTVAAFVMLKPWKERKEKSLSSAALVGSLYAQAQTKIPNAVVMPFNPPPIMGMSTTGGLEGYIQNRSSGGSDALEAQTQKFIEAAKKRPELSSVSTTFSAAIPQYKLDVDEIKAQAMGVPLSELYATLQGTFGTYYINDFTYSGRSFKVMMQADGQYRARPEQISGIYVRSNSGAMVPLSTLVTLTPTLGPDVVERFNVFPAAKIMATPAAGYSSGDAIRAVEETAKEVLDSGFTLAWTGTTYQEKISGNASAVALLLGMLVVFLILAAQYEKWSLPIAVLLAVPFAIFGALAGTWARGLSNDIYFQIALVALVGLAAKNAILIVEFAVMLKAQGYDTTRAAVEAAKLRFRPIVMTSLAFILGCVPLAVSTGAGAASRHAIGTAVVFGMLAATLIAPLFVPMFFTLLSGGRTKQLAQAVETSETKKENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKR5</accession>
    <name>A0A1Y4DKR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="7" type="ORF">B5F75_03335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56890">
        <property type="protein sequence ID" value="OUO56890"/>
        <property type="gene ID" value="B5F75_03335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="6">
        <location>
            <begin position="71"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="78"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="274" mass="30519" checksum="010AB4D6C285655A" modified="2017-08-30" version="1">MSLAENIKILREKTGAGLMDCKKALVECKDDMEQAIVFLRKKGLADMAKRSDRETKEGRVSVKTDGKNYAMIYLGCETDFVAKTDAFIKLADELAQYVLEHPGLDYSADENIKAMIVEQAPKFGENTTFKGGYNWTPAEGSVMAYYVHSDNKKASILELAVIGDCKDMEKAKEIARGLAMHTVGMQSGWVDAKDIPQAVIDRELDIYKTQAINEGKPAAAIEKMLPGKVKKFAKENCLLEQPTIKDNKKTVADYLAEESKNLGCELKVVRFVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKU2</accession>
    <name>A0A1Y4DKU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="11" type="ORF">B5F75_07110</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56041">
        <property type="protein sequence ID" value="OUO56041"/>
        <property type="gene ID" value="B5F75_07110"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="402" mass="44882" checksum="825B2B76BF52CF23" modified="2017-08-30" version="1">MRILGMIMAGGKGERLYPLTKDRSKPSVPFGGKYRIVDFVLSNFVNSGIFSSYVLVQYLSQSLIEYLRTTWRSEGIISDHFLTCVPPQMRLGEIWYRGTADSVRQNINLVKDFAPDLVAIFGADHIYRMDVRQMIDFHLKNKADVTVAANTVPLAEASAFGVLGTDETGRIIQFDEKPAQPKCIPGNPKAAYASMGNYIFNTDVLLQVLQKRFCDVPALDFGKHILPKILTDHRTFAYNFQSQTLPGAKPYEEQGYWRDVGTIESFWQTNMDLLGPKPKLDLNNPQWPISTTLNRVPPTKYMGGTVTNSIIGDGCIIHPKAKIKNCVISDSVIIGEGAELEGCVIMDNCEIKPGAKLKKVIMDRFNTIASKQTIGHNMEADSQKYYIDPSGIVVIPRGKSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL68</accession>
    <name>A0A1Y4DL68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like_fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56161">
        <property type="protein sequence ID" value="OUO56161"/>
        <property type="gene ID" value="B5F75_05960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005243">
        <property type="entry name" value="Redox_disulphide_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36450">
        <property type="entry name" value="PTHR36450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037031">
        <property type="entry name" value="Redox_disulphide_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00412">
        <property type="entry name" value="redox_disulf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="92" mass="9775" checksum="D83D6E42C28304DA" modified="2017-08-30" version="1">MKIQILGMGCSKCHILFNNTQAALQELGLPAELEKVEDFDRIAQAGVLQTPALRVDGKVILSGQTATVERLKSLLADCQSASSPSGNAQAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL79</accession>
    <name>A0A1Y4DL79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57050">
        <property type="protein sequence ID" value="OUO57050"/>
        <property type="gene ID" value="B5F75_04170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="385"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="503" mass="51118" checksum="A7D0326304211A7B" modified="2017-08-30" version="1">MNVFKFLKSISGKLVMGIPQLTAIAGVGVLAVYGAYEADNTVANKERALRSVSAISSSSAQEGLRRQKNGLLTSINIKDSLNQVATAEERAAIEAGSGSADNFGLDAVDNIKNVSFGPAAETSATDGLGMGANKAMEVGSSVRNAPAGSSSQVPAGAVAAAAMGAGSGEGAGPTLASASMARASGNAFNATSGPVASSSGSGSSAARSSSGVASGGRGAGGPSEGYQFSGAMPSGSNAVSSLTNARRSSSFTAGGRDSSVSRSRRSFKEKNELKDISKRSADVASNRNRAANEASRAWFASYKNSGGMQIDDLPNASESGGSADFENPTQQKLKGIGDYIPTVDEEAEKQDKARKRLMWMALALVAVTVVAIPLGYHLIAQGKKAGFLGISMMAYGWIVLGIAMAYAAVVFGFAADYQRHYKGWFMPLMGYGLSMGAIVALLYAGISAVKETGSAAANAKFMAKAMGAVKTVGMMGLTQGGSALVQKGMESDAKANADSNQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLI1</accession>
    <name>A0A1Y4DLI1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56261">
        <property type="protein sequence ID" value="OUO56261"/>
        <property type="gene ID" value="B5F75_06500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012441171" evidence="1">
        <location>
            <begin position="28"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="249" mass="28065" checksum="4AF1443B59CD58E3" modified="2017-08-30" version="1">MNKFLKSVFCLSFLATFLLAPSTPAHAQKWRTLKKALFLPQIQTQGIILQTRLERTVLRAVRRMPKRPYPLQVSFQQGAYHFTTPSTLLAPAGQLTYSRNLPPFPLPNQKNEMYRGMVLDEHGDDLRHILKNGLEVSKSHYEIFAPYNGVEYPEGTKAIYAAATSRQAIPFLIPDAGKTGLSVLLHLKRVGWRPVVSIPHDIPPSWILRVSALLNIDGQLRWGELKLNKDGTFSFFPYPPAPVSSVSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM08</accession>
    <name>A0A1Y4DM08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57330">
        <property type="protein sequence ID" value="OUO57330"/>
        <property type="gene ID" value="B5F75_00710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="19818" checksum="FB64E1FBA36087DD" modified="2017-08-30" version="1">MAKIKFGKKGHLELEITPLTIWSNPGSEGEFMEYQLGLFCEGENVFNPALEPKLVALKDEENVYLSDFIAETLAERKENNWMMLEPKVSLYMRPVPPPAGCCSAYNQPDNFLLQMTLEQNIFAGEDKVFGPYSNTGLTISFEAAGKDWADFAQAIRAEEEDFDEEDSPQEDPYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMP1</accession>
    <name>A0A1Y4DMP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_02005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57570">
        <property type="protein sequence ID" value="OUO57570"/>
        <property type="gene ID" value="B5F75_02005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004704">
        <property type="entry name" value="PTS_IID_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03613">
        <property type="entry name" value="EIID-AGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51108">
        <property type="entry name" value="PTS_EIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="273" mass="31518" checksum="391AB6162E959AE0" modified="2017-08-30" version="1">MKFSMRLNMFLRSFFLQTGWNFMKFQNLGLTFVMMPFLKQLYKDDQDALPSVLQRYLENFNTQPVMASFCFGALAKQEEAVARAESLTKFKEKVTEWASIKKSLSITTASIGDRLFWGTLKPLTLLMALFIWLMLGVNFFEIDLPQNTPLLYAFCAGGAAFFAFNAVALFVKWQGLKISYNADENSCFGLTRFDWNKTIYNAKRIGIVLAVGMILFGIYHYLKDFEEVDVHFVTRAVIVLFFVMISFVTRKLRIPNMYLYLAAVVVFNLVCYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMQ2</accession>
    <name>A0A1Y4DMQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">POLIIIAc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57590">
        <property type="protein sequence ID" value="OUO57590"/>
        <property type="gene ID" value="B5F75_02105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="271" mass="30047" checksum="7D1736BE5A37A2AD" modified="2017-08-30" version="1">MPKVDLHTHSNFSDGTSTPEEVVLSALKTGITVYALTDHDTTDGVRRAAAVCKEHRILFTPGVEISTREHDHLHFTGYNLDLDNADFQAFLAQNRHNRQERIRQIIRQLQQAGVDITEQDVFSRAPNTVSRAHVADALKAKKIVSSRQEGFRKYLVPGQPGYVPSAGVTAIEAIQHIKRAGGIAVIAHPGIVAEHWNFPAWTEAGLDGVEVFYPAHTFTMRQDLLAIARKYGLLATAGSDYHGPQGGRNSTPGMQIPQSHYDKLLRKLFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMV2</accession>
    <name>A0A1Y4DMV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_02430</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57650">
        <property type="protein sequence ID" value="OUO57650"/>
        <property type="gene ID" value="B5F75_02430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="133"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="249"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="369" mass="41196" checksum="E3AD91E2E386228D" modified="2017-08-30" version="1">MKINITKDTLLEGIQIVSAGVSSRTTLPILHNFLMEAQGGKLKLVRTDMEMATIHYVNAEVEEEGSITVPIKEFSDIIKNLPDDKEINLYSDENNKFHIKSGKSKFWVIGTPKSEYPAIPEVERANSVSLDPLLLQQMIEKTAFSASTQETRYILNGLLWNNTAEKFEIVATDGGRLAVASHEALPGSQEFKIIIPTKVLTELCRYITIAKPGKDSKIEVNVASNQVSFMMNETTFISRLIEGNFPNYKQVIPTKKNIGFEVFDKELLASTRRAALCAGEFGSVVKYKLENNTLTVSSNSQNMDFTDELPIEYTQEAFDAAFNPQYIIDVLKNISSEKVSFSFINASQPVLIEPVGDATFKYVIMPVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN18</accession>
    <name>A0A1Y4DN18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56801">
        <property type="protein sequence ID" value="OUO56801"/>
        <property type="gene ID" value="B5F75_02855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013073783" evidence="1">
        <location>
            <begin position="27"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="300" mass="34077" checksum="730E8F4409DDD120" modified="2017-08-30" version="1">MDNKMKRTLVCCVLFFSILLLPGVRAGAEGVKRGWEVELSKLSFDFNSTEVKNATEYKDFPQARLNADSQTAIRGFLDASADYYAHRYLWSNELILDYGRTKIRPVDGETLTNESADQILFTTGYTQRLWNIPNFLGGFELGPFANLGYETEFTKPEDAARKKVLRATAGVKLFEGTYLKSLFAAVVGERDYTYSPTSNKLAWEAGLKIEQPVREGVVAKYEVFFRDYLSESQSNQTDLDYEFSADARLEVQLYKNLYLAPFVSFYTAQAKYFGKRGENLYIGVSLSFSHLFKAADEISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN37</accession>
    <name>A0A1Y4DN37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_02965</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="10">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56821">
        <property type="protein sequence ID" value="OUO56821"/>
        <property type="gene ID" value="B5F75_02965"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004570">
        <property type="entry name" value="Phosphatidylglycerol_P_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000847">
        <property type="entry name" value="Phos_ph_gly_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00560">
        <property type="entry name" value="pgsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="206" mass="22930" checksum="DD062D79326297F2" modified="2017-08-30" version="1">MMTLANKITLTRAALSIVMFLFILMPFAWSRLVATLIFILAASTDWVDGKIARETNTITPFGAIVDPFVDKILVAAAFFAFVGIKELDIPIWAVFFILLRELMISTLRVIAALEGKVMAAERWGKFKTVIQMTAVGTIFFVLDVYHLAHILTGGAKSVCIILFITLQKIPYAITAIAAVITWISAISYLKNNWDLLKKSWSLPVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNH6</accession>
    <name>A0A1Y4DNH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56951">
        <property type="protein sequence ID" value="OUO56951"/>
        <property type="gene ID" value="B5F75_03650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="72" mass="7721" checksum="EACA647E9F0F8460" modified="2017-08-30" version="1">MRGIIFTVLTLIVGALIGLGLDKLASFLPVQLDQALSRVYAIGVHPLSLHISICGALGLVFGYIIISKFVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPJ8</accession>
    <name>A0A1Y4DPJ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin_lipoyl_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57311">
        <property type="protein sequence ID" value="OUO57311"/>
        <property type="gene ID" value="B5F75_00605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="327" mass="36129" checksum="E5A3521E22AC41AE" modified="2017-08-30" version="1">MIKKMLKRIWKPILFLLLAAAVVAGGWMWGVKPLIAKLKGDVIMPEDIVSVKKGSVEIFLKSQGTVMAKQDIKVTSKPSGILQAVYVKEGDTVKKGTKLALIKPGRNEFEDYKPVPIYAPADGTVVKCHADSKEYEKDLSERNLSLPRLGTFLEGSYDNTENATCLLRLVNTDTLVIPLYVSETQVLQLKKGMPVQIEVISLGDKAEPLTGKITYISTQIEKSGDRWSDSKGFLVLVELPRDGKNILLGVNTNITIVLQKSENVLTIPANALFEKDGKNYVFKYRGKNKADKTEVSTGLVNDTTVEITDGLKEDDQVLIALPYGESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPR4</accession>
    <name>A0A1Y4DPR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">B5F75_00835</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 11"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57351">
        <property type="protein sequence ID" value="OUO57351"/>
        <property type="gene ID" value="B5F75_00835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0639">Primosome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="13">
        <location>
            <begin position="181"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="372"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="472" mass="52993" checksum="17A8DB40D2A46C48" modified="2017-08-30" version="1">MASNLLEERIPPQAIDAEMAVLGSMLLDADAVTEALEILKPEHFYKEAHQKIFAAMKALADRSQAVDIITLTEELKKHHQLTQLGGEVYLTQLVDKVSTAAHVKHYAQIVYKKFVVRDLIRTATGLVQRCYKEEDDDPQILIDEAADQIYRLSQKQKLSGFISSKELAPEVIEILEKAVRNKSAIQGVPTGLDEFDRKTGGLRKSDLIILGARPSQGKTALALNIAHHACVDCNIPVAFFSLEMGRHIIFERMLGAAAMVEIYKLRTGYYEQSKWSDLTRELGRLASAPMYIDDTSGISITELRMRSRRLATELKKQGKELGLIVIDYLQLIRGGERRAESRQQEVSEISRMLKDLARTLNVPVLALSQLSRKNEDKSRTDNKPQLSDLRESGSIEQDADVVALIHREAYYKRDDESLKNKATLIIAKQRNGPVGDIDLAFFGEYALFTNPAPEHMENAQEMSGNTMMSLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPW1</accession>
    <name>A0A1Y4DPW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SpoU_methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57401">
        <property type="protein sequence ID" value="OUO57401"/>
        <property type="gene ID" value="B5F75_01105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="26143" checksum="E4C88DCA0CECA7FB" modified="2017-08-30" version="1">MSAFCIVLVRPRDPNNIGACARAMGNFGLSDLRVVDPYPPVWREAVSAVGVGDILQHAARCETLDEALADTQFSLASTALKNRDIRQEIITLPQLNERLARQQAQRVALVFGNEKSGLSNEDIERCDAVLNIPTAAKQPSINLAQAVILTCYELSRRPDFAALRTPGAGPQLPTDAQKEIFISAADRLFEKAQFKTDFSSAQRKALLRHMLAKQGLSREQLFFLKKWAEKLAEKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQH3</accession>
    <name>A0A1Y4DQH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="8" type="ORF">B5F75_02270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57621">
        <property type="protein sequence ID" value="OUO57621"/>
        <property type="gene ID" value="B5F75_02270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="7">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="6">
        <location>
            <begin position="93"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="20690" checksum="42C53A40D2FA54F9" modified="2017-08-30" version="1">MARYDNRREYKKDLYRRNQNIRVPEVRVINTDGTMIGVMPVAQAIALAKEQELDLVEISPNAQPPVCKILDYNRYVYEQGKKAAEAKKKQAKVTLKELRIKSRIAPHDLDVKIRQIEEFLRKKDMVRFVVVFHGRENQHKDIGIQILNDTAKRLAELANVDGGLQSMGNRMSMTFVPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQJ3</accession>
    <name>A0A1Y4DQJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57641">
        <property type="protein sequence ID" value="OUO57641"/>
        <property type="gene ID" value="B5F75_02375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="379" mass="41756" checksum="F6006B8CDB405425" modified="2017-08-30" version="1">MTDDKTPIPLFNLKEQHESLKPQINAAALEALNSMHWLLGPQTEKFEEEFAALIGVKHCISCSSGASALQIALGAAGIGPGDEVITTPFTFIATTSSISLTGAKFVFADIDPRTYNLDVHDVERKITKKTKAILPVHLYGYPANMDAIMHLANEHDLKVIEDCAQAHLAMADGVMVGGIGDAGCFSFYPSKNLGACGDAGCVTTNDDDIANRCRSLRHSGRALGKAYEYDLEGSTLRMDEIQAAILRVKLPHLEEWTEKRRRAAALYEEGLAGVPVVLPPTPPVGYAQSYYVYTIRAEKRDELQAFLKARGIGSAVYYPVPLYKQPAYKNRGFKPEDFPQAEKAAQEVLSIPMFPEITEEQIHRVCETIREFYEQDATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9Z6</accession>
    <name>A0A1Y4D9Z6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="10" type="ORF">B5F75_07070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56033">
        <property type="protein sequence ID" value="OUO56033"/>
        <property type="gene ID" value="B5F75_07070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="136"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="149"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="188"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="202"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="136"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="366" mass="39635" checksum="405B2BE89EFDDEEE" modified="2017-08-30" version="1">MKEDYYQILGVERTASEVEIKSAFRRQAMKYHPDRNPGNKEAEEQFKKVNEAFSVLSDPQKKRMYDQYGHEGVSGAGGFGGFNAGGFGDINDIFGSVFGDIFGGGFGGARRQSPRPQRGEDLKLDVTLTLEEAFMGKEVPVDYTRMDNCSACDGTGAAPGSARKTCRSCNGTGTVTYSQGFFSMRQVCPDCGGKGTVVEKPCPECRGSGTKRVKEKITVKIPSGVRSGVTLRVSNGGDIGTNGGGFGDLYVEVHVKEHKIFKRQGDDLVIDAQITYPQAVLGGSIKVPTIEGKEVELTIPKGTQFGSTLKLQGNGMPRLGKKGFGDLLVNIKIEVPKKPTPRQKELLEELAKETGGKKSFFQELFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA57</accession>
    <name>A0A1Y4DA57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56134">
        <property type="protein sequence ID" value="OUO56134"/>
        <property type="gene ID" value="B5F75_05800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="196"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="369" mass="42195" checksum="82814288C4AFED2A" modified="2017-08-30" version="1">MAVTVRQLSEQELDQFVDFPFQLYKNDPYWVGDLKADTAHLISRKNVFWTHGERALFMAFQDGKPVGRLMALVNRAHNEYQKENIGFFGFFDCINSQEVADALFAAGETWLRGKGVSAVRGPANPSSNHVYGLLVDGFDSMPAIMMPYNYPYYAQLIEGAGFTKIKDLLAFHRTKDDQFSERFLKVCARCSRGKGITLRRLNLKKIAEEAEIIRKIYNEAWAQNWGFVPMSPREMADVVKELKLVVRPEGTCVLEVDGVPAGFYILIPNMNHVLKELKGSLVNPWRVVKALWAWHKIKDARMIMLGVSPQFRQRGIDLILIKHIIDHGVAVWNEAELSWVLEDNEGIIRGITECGCHPSKRYRLYQKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA88</accession>
    <name>A0A1Y4DA88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4405 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56154">
        <property type="protein sequence ID" value="OUO56154"/>
        <property type="gene ID" value="B5F75_05925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025517">
        <property type="entry name" value="DUF4405"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14358">
        <property type="entry name" value="DUF4405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4405" evidence="2">
        <location>
            <begin position="73"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="224" mass="24826" checksum="7A41B66FD3267D7F" modified="2017-08-30" version="1">MTAKTRFKFSVDFVMSVLFLLALGYPFTGKLPHEWLGTALFVVFILHNVLNAGWYAALWKGKYTPFRWVLTTVNLLLLAAMIGLCVTGIFLSRDVFSVLHLGGSWTARRLHPVFAYWGFLLSAVHLGLNGGVFKPLLQRAQRRFSRWALGTAAGLAAAYGLFAVFYWKVPTQLGLAFTHMPRGRSFISFLSAHLAILFLAAGVTYWLVSKASSNKKISGGNPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAI2</accession>
    <name>A0A1Y4DAI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56234">
        <property type="protein sequence ID" value="OUO56234"/>
        <property type="gene ID" value="B5F75_06345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="163" mass="18279" checksum="AEB146CCDC767732" modified="2017-08-30" version="1">MSAKSASLKDFLTMTPVKIYDQEHIKSNIPHREPFLLVDEVWELDPDKKYLGIRHVRPDEYYFQGHFPGRPVMPGVLVVESMSQAFGGAIMSRTVGENKGIPLFLSIDEAKFRGMVQPGDTLQMPIEVLRLGKIAKIYAEAYVNGKLCAQATLNFILGETSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAS9</accession>
    <name>A0A1Y4DAS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56313">
        <property type="protein sequence ID" value="OUO56313"/>
        <property type="gene ID" value="B5F75_06780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="22450" checksum="0E6782A79C32FDC2" modified="2017-08-30" version="1">MDENYQKLFSEGKNVGFTLIELLVVVLIIGILAAVAVPLYEQAVWKSRSVPLQVWAKNLLEAQEAYYMANGRYTRCLDLLDIDYQKTFSKVITQESGYWDGGHWANDCVMTVATENDFPGMTLMTEGQFIRVVFSAGKYAEHGFGVYLSLPREDRKVGGVIKQCTNPNWPEWKKFLQSMGYQDVVVGTYLCYQQVNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAT0</accession>
    <name>A0A1Y4DAT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="9" type="ORF">B5F75_06850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56327">
        <property type="protein sequence ID" value="OUO56327"/>
        <property type="gene ID" value="B5F75_06850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="8">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="7">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="23638" checksum="6641F71D30B1FAE7" modified="2017-08-30" version="1">MSRYTGPSCKKCRKLDCKLFLKGTKCYTNCVIDKLAAVTKRGGKVRKAKVSEYGVRLQEKQKARLQSGMSEIPFRNLFDAAAKAEGQTGENFLRKLETRLDNVVRRLGFAVSLKAARQLVLHGCVTVNGKAVNVPSYQLRIGDKVTLNNALAENVQVKQALTEAEKRNQRPSFLEYDAEKMTGKLLRWPDRAEMSYPVNEQLIVEYYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB53</accession>
    <name>A0A1Y4DB53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FeoB-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56427">
        <property type="protein sequence ID" value="OUO56427"/>
        <property type="gene ID" value="B5F75_04325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="521"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="626"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="3">
        <location>
            <begin position="78"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="646" mass="71785" checksum="8D9812EEB873A2FB" modified="2017-08-30" version="1">MEKENSRSLYQVKPGQTAQIKEIQTDSKMAAKLAAMGLVHGQFVTRKPGSSPVVVSVSGTEVAIGRETAKKILVDAKKNTFLLAGNPNVGKSLIFSRLTGIGIISSNFPGTTVGLNYGQTQFGGEPYEIIDIPGLYRLEEEWVIEGRKHNLFKELEYDFIVCVADASHLERNLYFLLEIMQLKKPVILLLNKFDEAQRKGIQIDVKQLEKLLGIPVIAAVATTGEGLKELAFQASRIASHKMPESPLMVPPTPEGKWHAIGHIIHKVQTVKHKHATFWEKLQGWATTPATGLPIALAVLVLSFFLVRFVGENLIALLDPLYENYYIPFLQHLLAPIKDNTLGMLLMGDGVKYFGILTEGLHIALIEVMSYVLAFYALLGFLGDLGYLPRLAVLLDSLLHKIGLHGYGSLPIMLGFGCKVPAVMGIRILETRRERIIALALILVLAPCISQTAMIISILSPYGLKYMLIVFFALFINGILAGTVLNKLMKGETPELFMEIPSWQIPQLRPLLRKLWIRMREYLFDALPLILFGVLFVDLMQFSGLTDWIAKIARYPVEFVLGLPAETTPLLILGFLRKDISIALLEPFNLPPAELVVACVFMAMYLPCIATFFVMLRESGWKDTLKVIALTLSLAFATAFVLRMILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB74</accession>
    <name>A0A1Y4DB74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase IV</fullName>
            <shortName evidence="12">Pol IV</shortName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dinB</name>
        <name evidence="14" type="ORF">B5F75_04365</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56434">
        <property type="protein sequence ID" value="OUO56434"/>
        <property type="gene ID" value="B5F75_04365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03586">
        <property type="entry name" value="PolY_Pol_IV_kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01113">
        <property type="entry name" value="DNApol_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017961">
        <property type="entry name" value="DNA_pol_Y-fam_little_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022880">
        <property type="entry name" value="DNApol_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024728">
        <property type="entry name" value="PolY_HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11799">
        <property type="entry name" value="IMS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11798">
        <property type="entry name" value="IMS_HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="SSF100879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 12" id="KW-0515">Mutator protein</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="13">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Substrate discrimination" evidence="12">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="352" mass="39380" checksum="1B0DB4CCFF1950E8" modified="2017-08-30" version="1">MHIRKIIHIDMDAFFAAVEQRDNPALRGRPVAVGHDGPRGVVATASYEARRFGVHSAQSAARAKALCPQLIFIPGRMDVYKAVSRQIRAIFRQYTDLVEPLSIDEAFLDVSHLPCATQAAREIKAKIFQTTRLTASAGVSVNKMLAKIASDYKKPNGLFVIKPKQVEAFVAKLPVEKFFGIGKVTAQKMHRLGIYTGADLRQKSEAELTARFGKAGHAYFGYARGIDERQVEPNRKHLSVGAENTFAADTDDLSFLRRELAQLAHKTWLRAQRMHFSGKTVTLKLKYADFKQITRSQTFEQPFASEADFLHAGENLLLHKTNLSRQKARLLGLTLSNPPAPPLPGRQLWFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB81</accession>
    <name>A0A1Y4DB81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56437">
        <property type="protein sequence ID" value="OUO56437"/>
        <property type="gene ID" value="B5F75_04380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025931">
        <property type="entry name" value="TaqI_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12950">
        <property type="entry name" value="TaqI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TaqI_C" evidence="8">
        <location>
            <begin position="561"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="716" mass="80110" checksum="04D6E053D9B31404" modified="2017-08-30" version="1">MDIATLRRLTRIFEKSGWKKPEIYAFLRQFVIQRLAGPSFLLAKARAVSFFPAPPAAAQAILQGLTTGPEGSSGALAPQTLAVLYEFFQPKNKSRGVFFTPWGLARQTARAVLYEVLARRCGLGRQEALSLLEQSICPLPRARALALDAFLSRLSFCDPAAGAGGLVVPFVLELTRLRQTLNPALNGPHVLLSLIQHNLYAGDISKRALEELRLRLALVCRQQGLAVLPGNFCPHLFAADALACRNGKSIWRLQAKELFHADGGFDVILSNPPYLGQKGHSPVFEKLRRNPLWKPMAAPKSDLLYFFFYLALDLLKEGGIGGFLTTSYFTSAAGAFVLRKELKQKAAFLYLQNFENQRLFERAAGQHTLLSVFEKNNASEKPPCQIANQILPQAALYRTPALLIQTRVQQTPLESALLKMETCPHTLQEIACVTNGLMTGCDKISASHLRHFRLPGVKKGEGVFVLSEQEKDTLHLNAYEKQKLKPFFKNSDISPYTARQTPKRWLIDFFYPNDRELDFSRYEHLRAHLARFAPVLRARKQNNNGINKLLARGVYWFGSVRRKMDFEAEKIVVPQRSPRNTFAFAAGPWYASSDVYFISNPKDGFSLWYLLGLFNSAPYFAFLSCRGKRKGNLLELYSAPLKALPVPAAAPEIKRTVETLAQEIYRQKSANPQADIHLLQAQINQHVCHLLGLTAQEVQAIDTYLQALPACAAARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBK0</accession>
    <name>A0A1Y4DBK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Galactokinase</fullName>
            <ecNumber evidence="11">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">galK</name>
        <name evidence="15" type="ORF">B5F75_04840</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="11"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56523">
        <property type="protein sequence ID" value="OUO56523"/>
        <property type="gene ID" value="B5F75_04840"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00246">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022963">
        <property type="entry name" value="Galactokinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019741">
        <property type="entry name" value="Galactokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00106">
        <property type="entry name" value="GALACTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="6 11 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="14">
        <location>
            <begin position="9"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="114"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="284"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO56523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="390" mass="43670" checksum="4B33A14C019A6C46" modified="2017-08-30" version="1">MNQQALRSKFNEVFKKEKLYFFAPGRVNLIGEHTDYNGGHVFPCALSFGTHCVFCKRDDRKIRLYSLNFPQQGIIDADLDNLSYDKKQDWANYPLGVIKTLQNHGYKIDQGFELMYWGDIPNGAGLSSSASIELATAVAMNTVFKLLIPPVELVKLCQEAENKFVGMNCGIMDQFAIGMGKEGCAVLLDCNTLEYEYAPLDLKGISIVIMNTNKRRELADSKYNERRGECERALKALQTQLPIKSLGELSIEEFEKNKDLITNPVERKRAKHAVYENQRTLQAVERLKAGDVATFGKLMNESHISLRDDYEVTGKELDALAEAAWQQKGVLGARMTGAGFGGCAIALVKDENLKDFIDNVGKIYREKTGLTADFYIASIGGPARPEEKMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBX4</accession>
    <name>A0A1Y4DBX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage major capsid protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56654">
        <property type="protein sequence ID" value="OUO56654"/>
        <property type="gene ID" value="B5F75_05540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="398" mass="42870" checksum="76617D0D8DB76C9A" modified="2017-08-30" version="1">MDKEKTAQVSPEENGLKSLTEKLDTVLQAAEEASAKAAEADARAKEAEKRAQEAEAKSAKLSDELTAAKNAHAVNFTPKAQVKTFEEKRKGFRDFLTDVKAARFGNVKAALQAGAVTGSYLVPTGFLPEVLDLLGTNDDLIAQARRLPWGIEGDSRTIPNLVARSTWAFVGEGAAKPVSNPTFGEITQKLAKLSCIVVVTDELMDDTTIDLPALFAEQARAGLIDTLNDWLFNGDGDDRDGILGASGVQSPSVTGITDLLLLKQAVPVFVQRSGKFYLDNALYNELASMARINAPAWLYYEEGKMRVDGSEVVALDSDLIGARGAVFGDLKNVIFSPKNEFAIRYSDVATVVEGESPSQTTHHLFQENKQAFRFEMRADISVVGSVWAKATVPAAVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBZ3</accession>
    <name>A0A1Y4DBZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56674">
        <property type="protein sequence ID" value="OUO56674"/>
        <property type="gene ID" value="B5F75_05640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="81" mass="9393" checksum="2D99E0865E0751E5" modified="2017-08-30" version="1">MYEYKVISGQISVDYKKHETFESVLENMLQAMQNEGWEFYTPCTITERVSPGCLGSLLGQKEDVVSHQTFIFRRKKSQPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCB0</accession>
    <name>A0A1Y4DCB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56222">
        <property type="protein sequence ID" value="OUO56222"/>
        <property type="gene ID" value="B5F75_06280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="96"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="17865" checksum="BB1BEACBD093F530" modified="2017-08-30" version="1">MSQPQLQQQPPQFKRRTIFIKKNLQIRYMMLMIMSVLCGLAIMTFELTATLNDLFDTYPVLVQPIYDEFLPIAAGFFYKIAIYLLFVVIISAILSHKMAGPVYRFEQTCKAIAKGDFSQRVHLRKGDQLIELQDEFNKMMDRVEAEIHKNKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCB5</accession>
    <name>A0A1Y4DCB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56515">
        <property type="protein sequence ID" value="OUO56515"/>
        <property type="gene ID" value="B5F75_04795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="418" mass="45712" checksum="3E166B31D8E50953" modified="2017-08-30" version="1">MLLTSQSHKTPLQLLLTTEAFSSLTNQFMQILLPWYILSTTGSVLWTGVVGFCALLPNIFSSLFGAPVIDKLGRSKTMLSCEVIQLVLLGMIPVLIACGRDWPWLIGMIIFLSSFFDAPGQLARTALSPTFSRYADVPLSKTSGIIEAFDGIMSVVGPLLGGAIIALYGLLAAWIVCAAFCMVIVTLCIVVFTNRRPRQLHPVASYREVTAHLRADRSLWEPILFTIPTFILGQSWELILLPTYIYEHGFNSVYLGFLGAAFGLGAFAGALCFAALSKKFTFFKLLTLNYLGYLVSVLVLYFHLPTPIVLAATAACGIPFGAFGAMIISIILLRTPPPYRSKMLGLYATATYTVESLCVLGLAALIQAAGLQNTLLCVSGVFFGLVIISIWARRKDDFWTVLSSVNKKYLQNKTDLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCF4</accession>
    <name>A0A1Y4DCF4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DksA C4-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_05010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56555">
        <property type="protein sequence ID" value="OUO56555"/>
        <property type="gene ID" value="B5F75_05010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020458">
        <property type="entry name" value="Znf_DskA_TraR_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01102">
        <property type="entry name" value="ZF_DKSA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="5">
        <location>
            <begin position="118"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="22327" checksum="49B51C9D0DAC6037" modified="2017-08-30" version="1">MQGLGTFEKRILCSRPRPGRRVLLYESGWEKAFFKRGLKKKFFFAKLIKQCPENPSLPPHQFFPTGVFFMVTKKTNKEALTAAELKEIKKHLLELKEDAAARLKEKKNMDMPEAEVGDPIDDASKSLDKEILFELSGNAHSTIEQIEAALRKIDKGIYGTCEYCRQPISKKRIKALPFARYCINCQHSTEKHHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCH1</accession>
    <name>A0A1Y4DCH1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56803">
        <property type="protein sequence ID" value="OUO56803"/>
        <property type="gene ID" value="B5F75_02865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="65" mass="7199" checksum="88D00A3C328838DC" modified="2017-08-30" version="1">MRYNLFMLSKNLFSFVGNTSCALAVQEAVFASGLITRLFKNISKMISIKNMIVECDGPSGMIKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI8</accession>
    <name>A0A1Y4DCI8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FtsK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_02975</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56823">
        <property type="protein sequence ID" value="OUO56823"/>
        <property type="gene ID" value="B5F75_02975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="10">
        <location>
            <begin position="397"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="425"/>
            <end position="432"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="769" mass="85170" checksum="35E1C1D82D330226" modified="2017-08-30" version="1">MPKYYYAAKKSKKKTKKTSSRAWMRTVLYILAGALCLWLFCILWFNVSKGPAGDEVSTYLFQLLGQGSGLIPLFLAYWLIQTIRNKSTSFLFFLLGSSVTLAAFSSLLTLLKLIFTDSLISGGKAGQSLFYALKSVSGTVGATVFSLALALVGIHMLFAIPWAVILQKTVEFIRNDFNGWMDARAELKQRVSEGRAEIKEKSAQEPARPVAEEIHHAPEIHRSKPEIRRPVAEQITLPRREELSAPVPAQNAQTPDGEETGEVKKFDPKTFVLPPLSLLNNPAGDGVVGPTDEEIAQATRRLEDTLKSFDIRASVTGVSPGPVVTRYEIKPDPGVTIASITARTQDIQASMEARAIRVQAPIPGKNAVGFEIPNDRPVMVTMKEILQSPVYASSKAVLPIALGRYADGNPAGSAAEKWPHILIAGATNSGKSICLHTIIMSLMYKHRPDEVKFLMIDPKRVELTLYEGIPYLYDPKTSCDDVDVVTDANGAAKSLQMLVKVMEKRLQIMQLAKVKNIEGYNQWAAQNNEEKMFYIFVIIDEMADLMLQTKASIEDSIQRLAQMGRALGIHLILCTQRPSVKVITGVIKANLPSRIALQVASSIDSKVILDSTGAEDLLGKGDMLFQSTSDKNPLRIQGAYVSEKEIKAVADFLRAQGGPDYPVQIVAEQNPHQRPQDGLGASREELIQALNLIKERRRVSQDLLKAHFGSSARATNMLSVLEMKGYISKPEGSNRWEIHYEMIDQALEELNSLPYDKNYQEETYETVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCL6</accession>
    <name>A0A1Y4DCL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56894">
        <property type="protein sequence ID" value="OUO56894"/>
        <property type="gene ID" value="B5F75_03360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="238" mass="27103" checksum="060BCB6186AA9557" modified="2017-08-30" version="1">MTSPITRSRCEELLRRIKRFSSPAFKKQMSERFGICIDNALGTPVTTLRLLVKGLPRPDQELAEALWETGIHEARITASMLADPARMTREQLNDWAHALNSWDICDSCCNNLFSKVKNPLKLAERWIKREEEFVRRAGFAIICSLAAPRAKTKDEELIKLLPLIKNHAADPRPMVYKAVNWALRNIGKKNPRLTPKAIACAEEILDLYADNKSARWVASNALWELKSPKIKAMVAKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN0</accession>
    <name>A0A1Y4DCN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56867">
        <property type="protein sequence ID" value="OUO56867"/>
        <property type="gene ID" value="B5F75_03200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012486425" evidence="1">
        <location>
            <begin position="20"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="22886" checksum="3042187728275257" modified="2017-08-30" version="1">MKTVLVLAALAMPIYPAQAGGFFGKKPQVLSWQEALTNANRKVDNEGAASVLGVRVGEHVRRIGLHATLHKHMQDFFQSLRRTGSTEAAARKCQANYELIKQTALRNPLFAHYELTALVPGDFCTLSAQELTRIRRFFQGVQPLEQALAYQKVFLLTLKEGTARMWFVVNPQDKTLTFNYNDPRDLETLDELKTDWKPLLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCP3</accession>
    <name>A0A1Y4DCP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FtsA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56934">
        <property type="protein sequence ID" value="OUO56934"/>
        <property type="gene ID" value="B5F75_03565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="384" mass="42034" checksum="C66657395ABD11CB" modified="2017-08-30" version="1">MNRDILSLDFYGGEITAALAALDDETDTLRIRHMLRRPCRSFAGAFVRDMQGAQEELGKVFAEVSEYVSFDPAVVVGLRGNFLSFKRSSGFKSIESRHRIIGPREMEEAARSSVPLNLSDRLEVVDILPQFYSVEGNIGIKNPQGMTGSLLEVETFLSFAASSHLNNLNQVFNACHCTEYQVLPSSVALGETLLSTEEKQAGALLLDISANLTSGLLYYKGTLMDGWELPFGTDRLLEAASDLLQNDLETTRQTLRGYEPGTDEITDEIIEDAAEKLTSALSKELCQSLPYLQHLPARLVLCGSGANKIVLKSAKQTLGIRKARIGVFDDLISDCPTDNPAYCGALALIRHALDRESKQLGVAKTKEPGLLDGILDKLGLSQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCR4</accession>
    <name>A0A1Y4DCR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56816">
        <property type="protein sequence ID" value="OUO56816"/>
        <property type="gene ID" value="B5F75_02940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="162" mass="18863" checksum="6EE3CF0E7C28F838" modified="2017-08-30" version="1">MNGWQRFALLILCCFTVMVLYPDFGTSGWTFIGVVFAMWTGVIMVLSVISNLFGLYNLETFNKLITFVLLCAIMYSLLWYFPQEDKVTPINKIKYGEIPTKADIEKGLKRFTFNFDFVRRNARRKENFINQDLDGDKVKDQIKKKVSETTDDLIESIDIQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS3</accession>
    <name>A0A1Y4DCS3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56655">
        <property type="protein sequence ID" value="OUO56655"/>
        <property type="gene ID" value="B5F75_05545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006433">
        <property type="entry name" value="Prohead_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04586">
        <property type="entry name" value="Peptidase_S78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1188">Viral release from host cell</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="23674" checksum="172989848E21CA44" modified="2017-08-30" version="1">MDIKKYEGKKEFVLTDFKELETDGVLRISGYANNKHIADRYGDIPTEYNRSYVYELEEYRRNPVLLMDHDHDVSHMVGSVTNIFEDEKGLYFEAEISNSDLPIIKHARQLIKEGHLKTVSIGGVWLYEDLQNPSHLTLAKIFEISLVAVPADTYAVFAPKTPAEPAKSAARMDLRSAFGKLAVFEMKQKISKFEAKSKQPDFGQGAKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD38</accession>
    <name>A0A1Y4DD38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57043">
        <property type="protein sequence ID" value="OUO57043"/>
        <property type="gene ID" value="B5F75_04135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="455" mass="50042" checksum="F6798A50E1EED0B2" modified="2017-08-30" version="1">MAKKIYPQASLGELWHLSYPLVVTMAAQVVMQFVDRMFLAWYSHEALAACVPAGVLAMTFAAMFMGLASYTSVFISQYYAKKKYASVTVSLWQGILLAVLSSLVLAGLTPAGKAVINAFGHDAPVRVLELEYFAILNIFGGLAVINNALASFFSGRGHTKIPMWAAVVGNLVNVGLDYVMIFGKLGFPAMGIKGAAWATIIGSASITLIFCTLIFAGKTRKEFKISRLAGFYKPVFSRLLRFGLPNGFGFLMDILSFTLFTFMIGNIDTLSLQASNVVMSMQPVVFTVILGLGIGIQILVSKYQGLKRPDLSVQVIKNACKIGYAYAGAVGVAFFFFAPFFVGLFIPASSPDAALISEKTYPLMKLVSFFVIFDATYLIFGEAIRGAGDTKFYMYIMLFCAWGLLIPGTWLIVYKLQWSVFWVWSWLTFYAALTAVFMLGRFLSGRWKHFNVTGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD47</accession>
    <name>A0A1Y4DD47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57054">
        <property type="protein sequence ID" value="OUO57054"/>
        <property type="gene ID" value="B5F75_04190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="21105" checksum="024AD4BEBD946985" modified="2017-08-30" version="1">MKRLFSFRSKKGQATTEVVLLFPLFVIFILFIIKIFGLLILSQKMEIAGFYAARRFQLQSHETDYYANTWDRRFLKKDIQKKVENYLGFDNPGMRKFLSLSELKMDIETSGTWTKVVLTAHTRPPRIRFLCNYNKDQVCDRDGKCLKGYAFLCETGGQVEIIKYVGHNERPAPYQRPEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD89</accession>
    <name>A0A1Y4DD89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56835">
        <property type="protein sequence ID" value="OUO56835"/>
        <property type="gene ID" value="B5F75_03035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012938049" evidence="1">
        <location>
            <begin position="21"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="464" mass="52189" checksum="6E40B7D6BD5EE327" modified="2017-08-30" version="1">MKKIFVLLLFCLCACMPAHAWVFLQSVQENKNTSVLLPKIINRQAHIRVCMDLLDQNSRPSSNPSTANENSDTYQKIRPIIESSYQMWMDTLRNTIQSSGRSAEFADVLSLLPKKKLTFEFINPDLSPCVDDKAQDLYVRVVPGVQAPGAAAYVRVHNNLVAMTLDKWDVYSPEELRGHVLHEIGHTFGLGDMYQSSAKKSYNSRTYTTADIQPLWETAACMNDSCNGYTKRVPYSETQAVWDEARGGFRSISKSRYKTVFVENSAEKLTCDDMDGLVNLLDYYFPEKMSKRRTEGWLSFCRDKNLAYAYSLPFTVTPEEKAAFAQFVKKGRLGLSPLIGKTEFLANYTKNIVNGTAPTGYSLRRKQLQQQAKQELSQAVVGNQKPAAAAPTVPDECPVCHKPLRGTDAIRLCDRDSKRRIRGGCVYLHRGCKGNLGNPDALKSFLKTVDPKYVGHSEKTRVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB8</accession>
    <name>A0A1Y4DDB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56632">
        <property type="protein sequence ID" value="OUO56632"/>
        <property type="gene ID" value="B5F75_05425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="191" mass="19443" checksum="0EC6E87BA1A96136" modified="2017-08-30" version="1">MASDCFNLVCAEGTIQNTNTACGKCGVIQRQCVKGDWVESCVNETGVCTPGTFTTEGGSRCSSGGFAQPGSGLVVSRPVTGGMEVVGSGSSSNLKDPSLSSGGTTTTQPVLASYSGRYCNDQCSWEILPCKNTGGSSGGGASGCSSKTREFTNMDANSNFQRCTVIEQTCNSSSSLLLDTLNCTSVTGSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDG2</accession>
    <name>A0A1Y4DDG2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="6" type="ORF">B5F75_03350</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57076">
        <property type="protein sequence ID" value="OUO57076"/>
        <property type="gene ID" value="B5F75_03350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="19"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="124"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20777" checksum="DB8FCB37D3D2821C" modified="2017-08-30" version="1">MSNLLNKTKTNMAEHVSRLERDLATIRTGRASAGLLENIRVEYYGTPTPIKQMAIINVLDAKTLEIQPWDVSSINDIDKALQKADLGASPVNDGKVIRITLPSMTEDRRKQLAKNISKMSEDFKVAVRNERRDVIEKLKKAQKAAEITEDDLKRYEADVQKATDANIAQIDKVIKTKEDEIMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDI2</accession>
    <name>A0A1Y4DDI2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56925">
        <property type="protein sequence ID" value="OUO56925"/>
        <property type="gene ID" value="B5F75_03520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169746" evidence="2">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="374" mass="41188" checksum="C2859F95FB718F70" modified="2017-08-30" version="1">MKHKVTCLLAALLLAACTAQRQTVAEPDSPAPVFAAAPVSAPAEAAPAEAAAPAEKPAAKPSIPVNPAVKTEPQTQAPAPAAAPAPSSPQQEEPSPTPQALIRQARQAQTLSAPPQDTPAFEDEDLISLEGRRLSPLAYSPLRPDTTQAPWSAEELKYGVYYTFIRAGTAYIKNRGLTTVNGRDAYLLQTTAFSASVIDAFFKVRDVNYSWLDTENFYSLGYLQSVREGSYKRDEWLTFDYPRQLFYGEVQKKEDPRVISGGLSMRVLDMLSSLYFVRAQKLEPGKDIVFDIINREKQYPLVVKVLGKETVKTDAGEFDCIVVEPQFRGEGIFVSKGKSLKVWLTDDAYKMPVKMKAEVFIGSVSAELLEYKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDK9</accession>
    <name>A0A1Y4DDK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="11" type="ORF">B5F75_03670</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56955">
        <property type="protein sequence ID" value="OUO56955"/>
        <property type="gene ID" value="B5F75_03670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="210"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="583" mass="67161" checksum="0BC6E50D4D702883" modified="2017-08-30" version="1">MENKQLETKRHSCAHVMAQAVQQLFPGTKLGIGPAIENGFYYDFDCPHQFTPEDLKAIEAKMKEIIKARQPFERKEMSKAEAKEFFTKRGETYKLELLDELEDGTITVYMNGDYADLCRGPHVEHTGKINSFKLTTIAGAYWRGDEKRPMLQRIYGLCFDTKDELNAYIKQQEEAAKRDHRKLGPELDLFSINDNIGPGLILMHPKGGMLRKILEDWIKDQNLKRGYDLVVSPHIARLHLFEISGHAGFYSDSMFHPMEVDGEKYQIKPMNCPFHVEIYKTHLRSYRDLPLRLSELGTVYRYERSGALHGLLRVRGFTQDDAHIFCTPEQVEDEVKQCFEFAMHIFKTFGFEKYAVELSTRDPEHPEHFTGDVKDWERAENALKHVLETNHIPYTTHAGEAAFYGPKIDIKVMDAIGRLWQLSTIQFDFNLPQRFNLEYVAPEGRKRPIMVHRAMFGSLERFTGVIIEHYAGWFPLWLAPVQIKLLTLTDDQIPFAKEVYAKMRQAGLRPELDVRPEKLGLKIREAHMQRIPYTAIIGAKEAAEGKLTIRLKGGENTPALPVDEVIAKMKEEVASFSLTNLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDR0</accession>
    <name>A0A1Y4DDR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57005">
        <property type="protein sequence ID" value="OUO57005"/>
        <property type="gene ID" value="B5F75_03930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013368375" evidence="1">
        <location>
            <begin position="20"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="355" mass="38428" checksum="55B851320583BF08" modified="2017-08-30" version="1">MKKLISLLSVFFLSTAGYAANKIEMVTYFPVPYVAYSRVQVDKILDIGLTNVCNMSLGCTESGNAGLRPLHVQDAYLETGSLDLTRALAVRSNNVSLGANAGEANIDFNDSLRIKNLNDGYSLETSQLTVDALKLFPNRIVNNFPSCAATGADGAPQVSWQKLKIKDKEETFLVCGTPQQVDCSNADYRKDHKSECCPQMPVSDSVCYKDCYGVSWGPLGGTVETALGSDWIARSCSRKAENGSHRRCSGEAGDWDALYGEYSCWKSTAYALTKGFTFAIYGTGTGFSNCVEQLPIACVEESDAGQTCIVFDGDAWIACEWKTGGGLVSATYNGGVGMWKCQIDTSIVTRCKNGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDR6</accession>
    <name>A0A1Y4DDR6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argS</name>
        <name evidence="12" type="ORF">B5F75_00345</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57264">
        <property type="protein sequence ID" value="OUO57264"/>
        <property type="gene ID" value="B5F75_00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="413"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="530" mass="60037" checksum="746E04B6B13B6A0B" modified="2017-08-30" version="1">MLEKLKQDITLKLSNADYFKGFELPEVEFSAAPAHTGADISLVWAMAAAKKMHKNPLEIAKEACVVLREITAIADASALPPGFINLKLEDKFIIDTASDRRIKDRGAETSKHNILIEFVSANPTGPLHVASGRGASLGDSLVKIHRALGYSCDSEYYVNDAGNQAQLLAESVKARKEGKEPPENGYHGSYLIDLVKRMPADLQEEDYGRWAMEELIKTQQQDMKDFHVDFTRWFRESDLHKEHAPQKALQALTEKGYTYEKDGAVWFGSTQDAEAQDDKDRVLVRTDGRPTYFLADIAYHKNKYDRGYDTLIDILGADHHGYVPRMKAAVHALGKEESSFVPIIHQLVHLTEHGEQVKMSKRAGRFITLRELMDEVGTDVCRFFFASRTPNAHMLFDMDLAKKRTNENPVFYVQYVHARIHSIFKAAAEKGFTQYNGVRTPLAPQERALLLKLVWFKQVLRNCVADLSPHHLTTYLVELAGLFHAFYDTCRVLDEDNPEQTHSRLFICQRVAERIKKGLEFIGVSAPEVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW3</accession>
    <name>A0A1Y4DDW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56832">
        <property type="protein sequence ID" value="OUO56832"/>
        <property type="gene ID" value="B5F75_03020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010997060" evidence="1">
        <location>
            <begin position="30"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="651" mass="73283" checksum="730E7A7C38DB7DE9" modified="2017-08-30" version="1">MNPRRKTAKILLISLFVCMAGINAAPAQANTFTKLLKGFFGSKNAEKMAKPAPPAVVPQAAKQAAEASKLVSPSAAASSAAPAAGAALQDNSMVILESVENVPNKNDQYFLTPKEMWKKSVKEFYSTDVLPKTPKTKRTGEDRILKNTQQDLPAPNRMKNAQIEENFQNMSAVESAINRQIFQQDAMAENQVNPDIQDLFSFRTGMEALESLMPSYKEILSMRCSPNERALLLNTFKNLDKEFFYYNPSKQTSYMVPRTEHLYSTMFYKQFAQDNPTLNIRNITDILERTGTDKVLTVIDTKLWMTSHNGQLPRFLANKTLKEQQVAINFYNLLDEAKSNTLPVHLRPLKQVVLSIGKPIQGSIPLTAWTNFTGKWLATFSDEELVKIFLNYNKPPQKAFFDGMAADIRKGLSGKLSSDKTGQTLYLLGTANATPQQTLSMLKWWAAQKNAALPRAAGNPRTLTENTDYAQVLARYREGVLFDNTLRTLDAKGPAARQAHEILLPLAQNYLRQTAQRLDEAKQLLDKGEIKQADVKALHTDIQNPLLKALAPRETAQLNVRIQTFNKLYKKYNDVAKFLTYCRMHPNEYFYEEGHLIVERLIPSLRERWGMDASVAELQQEISELRASGLVSADLLELQLQRLVKKGQGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE13</accession>
    <name>A0A1Y4DE13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56892">
        <property type="protein sequence ID" value="OUO56892"/>
        <property type="gene ID" value="B5F75_03345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="426" mass="48039" checksum="CC7E5C5CEF03BB68" modified="2017-08-30" version="1">MKKHTNLTVFLILVGLLLASICSLIWQVKRSLAEAPRAQEELNVAPVPAAPREEPQPLPPVPPKQTAVTLPPAEEAPAPSPILSNEELLQLAKQDLAPFFPPDQLEEMAKRTQNIVLYPMVIAAGTKIIHAKYPKTDPTLEQTRTEQIKALQRTVFDIRKRIQKNDLLKKRVPPEEQKNWLEQSPLHRKNISIAGPKGQTPLRRITVSCPPWQKDYDLCEQVFYSKNEFSLFLFKNDILLSREDYQAPKKLSAGYMFFPPNPYKSGESAAGQELLQGRVSYCAHWDSTHPLPLRESRYRENGLLQQNLTRNFEENTQQTIFYDEKGQFTQLDISSISTTGRAKLPQSLAIMSRKYASPTASFASEGSYRKDVSAHASGRWTASPDGTVTLDEGRRFPPAQSFPRAPLYRDIYPAQVPAAQTAPELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE50</accession>
    <name>A0A1Y4DE50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000007">
        <property type="protein sequence ID" value="OUO55979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55979">
        <property type="protein sequence ID" value="OUO55979"/>
        <property type="gene ID" value="B5F75_07230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO55979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="336" mass="37498" checksum="D9069A9875461A63" modified="2017-08-30" version="1" fragment="single">YVKPGIYEIRLTAKNYPDPGLYQETVKSVTVNADLLKVFDLLEADGYSLAQRNTEMKIGYQISVPMKVAIQIFKPGTTIYDYQKGTLRNPTTGTEVKDIHEVLVKAIVGIRPATTLIEESWDGRDYAQQEVPDGTYPFRFVTALNSADIDSVTGEILGSDDSSTNSAMWSIDKVADTYEYQNLHKATVAIGDGRFVCEDWEKTVFFYPNPLRDASKGTLEITKMPVPGTVSIKFFNLAGDLVRDSNYTCVDANNYQVTMGSSLQFNPDNTPEGSTQMDAEDLAAFPNLRNAALRCRWDRTNQHGKKVARGVYFGLVDFKAQNGREHCQKVVKILVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE79</accession>
    <name>A0A1Y4DE79_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57433">
        <property type="protein sequence ID" value="OUO57433"/>
        <property type="gene ID" value="B5F75_01280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20378" checksum="AA4EEF5290D2BBD8" modified="2017-08-30" version="1">MAKIYQKSFPGGKNAGFTLIELLVVVLIIGILAAIAVPKYQSVVDKARMSDYIQRAYGIKRAQEAYYLANGEYAADLRDLDVNYVEDCEPALARGNEWICGKDFFIHNMMPQGAYVGGAIEVFLCPDSTVGCITCSDKQLARIRIGFDHGDYVGDEVCIYRVRESTQRGKQLCATLGFKNVIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB6</accession>
    <name>A0A1Y4DEB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57245">
        <property type="protein sequence ID" value="OUO57245"/>
        <property type="gene ID" value="B5F75_00235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="75"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="285" mass="31949" checksum="A2D477A6CE0AF90D" modified="2017-08-30" version="1">MPSGAWKSYNIGMIWVLLFAVLAGVWYGLSRLGAHIVFRPQKKRWPLTLPFQNAAFDAPDGTPVTGVYLPAQAGRPTLLFFHGRGGNVSHFEKFAQVYASKGYGIFMFDYRGFGLSKGRPSQKHMFEDALAAARYLMNTLHIRPQEIVLYGHSLGNAPALFAAQTLGKLPFKALILQSPFLSTPDMAVCLWKHVYEPASFFYRATKVFVTPFLWFNRFENTLPAGQIKLPALVCMSRADATIPWKMSAHLADYIPHTKRFLSEHGGHDEFDWAADAADAFLKNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DED0</accession>
    <name>A0A1Y4DED0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AlbA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56992">
        <property type="protein sequence ID" value="OUO56992"/>
        <property type="gene ID" value="B5F75_03855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="394" mass="45095" checksum="502D6387115A1FBE" modified="2017-08-30" version="1">MFFDKPFHDLTFHDVVQFCRRQLPEGKQLDYKYMLPKNHEKFAKTIASFANAMGGTIIVGVQDDKNDKPRPPFLGIPYHEKMRNSIEDIIQVYIDPIVFVDINICVNDRGDRMFVLINIPQSNLTPHLVGKSKRAYIRTGQSSRPEAIVHPEKLPWLLDHRRKSERLRHILYDKAESHFDNYLKTMNLSADGQTACTMSVIPLYPEEPLTDYKHLPDIIKASSAKAPYGIMADPAFPLQPVQDGAAVISNKRGVYRMTEFNSYGLVMRKQIITQEEIVNGHAAKTVRIEHLGQTLTLFLLTARKFLTHLSFGGPLYFRLKMNNTRALRALLGPKQATVLEDYLRMDRNLSLAELDTKLPAILENILHEAAWSLGLQADEAQIRTLLRQYLKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DED4</accession>
    <name>A0A1Y4DED4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">murB</name>
        <name evidence="18" type="ORF">B5F75_01300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57437">
        <property type="protein sequence ID" value="OUO57437"/>
        <property type="gene ID" value="B5F75_01300"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="28"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OUO57437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="33177" checksum="2FE2E6CDF1D00CCC" modified="2017-08-30" version="1">MDYKQELKTFFKDNCLLDEPMARHTTYRTGGKAEVYVYPKTREEWSFVLKLAETENIPLRIIGFGSNILVSGKGIGGIVCSTKRMNQVTLDGEHIKAEAGAALDKVCEMACEAGLAGMEKLSGIPGSVGGAVYMNAGAFGQETFDCLEYFDIIDREGRPATLLKEEVKHAYRKVEGVQDCIILSAGFKLQKGEFTQLIESRNTVLHKRMEKQPLEFPSAGSVFKRPANDYASRLIDDTGLRGLSVGGAKVSEKHAGFIVNFNRATPQDIKTLMDVVREKVKEKHGVELELEQILWGDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG6</accession>
    <name>A0A1Y4DEG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57032">
        <property type="protein sequence ID" value="OUO57032"/>
        <property type="gene ID" value="B5F75_04080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012576507" evidence="1">
        <location>
            <begin position="22"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="374" mass="42033" checksum="AE4E228490BF0968" modified="2017-08-30" version="1">MKKIVCFLLLVVLVFPQSAFAQAAKALRPLLPALSKSGVQAAGGKCLSFELGNMYMYLPPAVMSAHGADLWNTHISAQLDPALYGAVSKKNNAYIFKSLQRFTQNYEKFHAHSASIVGRIQSCVYTGDIPYAAYLPKDLKTLYLGEVHGIVPLAEEVTRLIQALPKLYPGRKIYLATEFLPAYEQLPLGADRTVTRPEEIAQLLPDTRRVSVRVLYAAVKAGIPVIGLERENELQNFIVRTTRQKPTDQMYEDFSCSFEGVRLRNKMWAQYLRALRQQEPDALIVVYAGFGHVGYNQDFNLPSMLGGDSFVVLFTVPEYLTLNNPLFIYFREEAAVRAQFHSSPRARLVESWVKPSPYKKILGSDMTVILQSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH5</accession>
    <name>A0A1Y4DEH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57563">
        <property type="protein sequence ID" value="OUO57563"/>
        <property type="gene ID" value="B5F75_01970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="74" mass="8344" checksum="66F89D339A89A207" modified="2017-08-30" version="1">MAEKVLKVGMDREDGFLYYIDKDGDIARVQMARGGKKGGKPKKVEKCGIKKEKGYLYFLDKKGDISRAKMVNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH8</accession>
    <name>A0A1Y4DEH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57042">
        <property type="protein sequence ID" value="OUO57042"/>
        <property type="gene ID" value="B5F75_04130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="97" mass="11263" checksum="99F46C817D65A222" modified="2017-08-30" version="1">MGKLVLKRGLLKGRVFLSAAEFNGVLVAFSIDKKHLFCYNNFIIKRTVRFVIFLSGASARFPLFFFRFWPCLFVQAWLSCRLLTKEFLCLPKPVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL0</accession>
    <name>A0A1Y4DEL0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57335">
        <property type="protein sequence ID" value="OUO57335"/>
        <property type="gene ID" value="B5F75_00745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="153"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="294" mass="31048" checksum="3C88DD76F21928D3" modified="2017-08-30" version="1">MNKTRLAVIYALTAALCYGLSAPFSKLLLRQISPAFLASLLYWGAGLGMLAVYVFPAKSAPSAPALSGKDFPWLAAMVLLDAAAPMLLLWGLQTTTPATVALLNNFEIAATALIAFWLFKETVSKRLWAAVVLITAASVLLTVDDFSALSFSKGALLALAASICWGFENNTTRQLSAKNPVQTVMVKGFGSGSLSLCVAAYTGQIHLAPGYILGALLLGALAYGCSVYFYILAQRYLGAARTGVFYAAAPFMGVLFSFMLIGQPIGWSFCTALALMLAGTWLAAADTSSRPEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL3</accession>
    <name>A0A1Y4DEL3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57527">
        <property type="protein sequence ID" value="OUO57527"/>
        <property type="gene ID" value="B5F75_01775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013345557" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="299"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="442" mass="47436" checksum="ED6CCA04209D3C67" modified="2017-08-30" version="1">MRKSVFAVCCLLAAGLLQAETIKMKTGELISGSILSQTEYTLNLATSYGNITLNQREIEQILPDKHRLILKGGTQLVGVILDLDEFNLKLQTDDGSIVNVDMPQIISIEVYDYDQGEKAQQKFVQENIQQQQAAAQAAAQQSAPADTVQAAGGLTFDSDINQVFDAQTATVVNGSVVTPSARVQTAAPKPMTDEEAFLKGVKTGAVSQQEYAAAAKEELTAKKPTAKKQTPKKTYKEKDFNKYFAVEAGAMALDLQASGVLKLGDLATVDLGDNTQDMGGTSAVISSKFLWRLKESNLWIGPMLTFASIANNDYSFSLPSLGSVSASSSGNILTVGAAANYYLNPAGRFSFYLTANAAYEMLTLNYRGNITTSSSTGTQELPFRDSLTSNGFSGALGLGVETWVDDVMIGLEVRQVFAPRSGELKESAVSNTVAQAKLSWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ9</accession>
    <name>A0A1Y4DEQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low specificity L-threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57556">
        <property type="protein sequence ID" value="OUO57556"/>
        <property type="gene ID" value="B5F75_01930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="3">
        <location>
            <begin position="15"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="38839" checksum="E2EEB4174C172AC0" modified="2017-08-30" version="1">MIRFNCDYSEGAHPAVLEKLALTNLEQTPGYGQDIYCRRAADLIKNLCAAPDADVHFLMGGTQTNLTVIAACLRPYQGVISATSGHINVHETGAIETTGHRVITVEEQNGKLTAEQIARCCQEHWQDDNPEFAPQPKLVYLSFPTEYGTLYSKAELTAIRRVCDEHNLFLFMDGARLGYGLEAPGNDLTLSDIAACCDVFYIGGTKIGALLGEAVVIVNPKLQKDFRYFMKQKGAMLAKGRVLGLQFLALFENGLYFKISKHADDMAQLIRRACQEAGYSFLYDSPTNQQFPIMPEKTIKQLEEFYAFSHTRRLDRGRAAIRICTSWATREEDVRQLTADIRKYAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV3</accession>
    <name>A0A1Y4DEV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TlyA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57606">
        <property type="protein sequence ID" value="OUO57606"/>
        <property type="gene ID" value="B5F75_02195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Haemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="PTHR32319:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="254" mass="28284" checksum="533ACFBE4C7BA793" modified="2017-08-30" version="1">MANKKLRLDMALVEKGFFPSRNRAQASIMAGEVLVNGEVDTRADRTILPEDVIALKEKSCPYVSRGGLKLAGALKAWNIDLKGKVCVDIGVATGGFSDCMIQAGAKDVYGVDVGKGQLADEMRRYKNFHFKPETNARYMTADLFDQAPQFAAVDVSFISLTMIMEPLFKVMAKEAEIVFLIKPQFELTPKQVPHGIVKTEENRQLAIRRVQDFFEENLKEKYGGVSGEVIESPIKGTHGNTEYLWHVKLNKPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV4</accession>
    <name>A0A1Y4DEV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="1">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queF</name>
        <name evidence="2" type="ORF">B5F75_00560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57703">
        <property type="protein sequence ID" value="OUO57703"/>
        <property type="gene ID" value="B5F75_00560"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00818">
        <property type="entry name" value="QueF_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016856">
        <property type="entry name" value="QueF_type1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027377">
        <property type="entry name" value="Nitrile_oxidored_QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03139">
        <property type="entry name" value="QueF-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="70"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="132" mass="15154" checksum="FA1875EE87F6FA69" modified="2017-08-30" version="1">MHDIDFGYTSDHARKNADAVLPDIQCWPNQYKRDYDIKIELPEFTSVCPKTGLPDFGVITIEYVPDELCLELKSLKYYLLEYRDMGIFMENIANKILDDVVKACKPKRAVVTGVFTPRGGLRSVITAKYEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW6</accession>
    <name>A0A1Y4DEW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpC</name>
        <name evidence="9" type="ORF">B5F75_02500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57664">
        <property type="protein sequence ID" value="OUO57664"/>
        <property type="gene ID" value="B5F75_02500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="136" mass="15171" checksum="0C62FFC4C9E626DF" modified="2017-08-30" version="1">MSKKLTLNLITPEKQLISNREADMVVLPALLGEMGILPGHIKTIVQLGMGSLRYKNDGKEEEFAVLGGFAEVLHNVVNVFAEGADLADEIDEEVEKQKIKAVKESLSRKDADIDFELAEIEIKQAIARMKVKKRHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF15</accession>
    <name>A0A1Y4DF15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57232">
        <property type="protein sequence ID" value="OUO57232"/>
        <property type="gene ID" value="B5F75_00170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="75" mass="8091" checksum="F16E4C142228CFBA" modified="2017-08-30" version="1">MHGPVDESSHQTERFACVVSMMIFPRAAAGFSFPCGALFFIVYQRSSACPFIIGLVAAVPCGQTAEQTLFVVFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF31</accession>
    <name>A0A1Y4DF31_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ORF">B5F75_00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with KhpB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57252">
        <property type="protein sequence ID" value="OUO57252"/>
        <property type="gene ID" value="B5F75_00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="76" mass="8198" checksum="BE30B00728D6D250" modified="2017-08-30" version="1">MKELATLLLKSLSSAPENVVVEERVEQNKVYLSTKVDAADKGKVIGKDGCIIKAVRTVLSAAAAKQDKKVTLKLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF34</accession>
    <name>A0A1Y4DF34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_01815</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57535">
        <property type="protein sequence ID" value="OUO57535"/>
        <property type="gene ID" value="B5F75_01815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="159"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="258"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="394"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="450" mass="48580" checksum="918B845DA0D4124A" modified="2017-08-30" version="1">MGKYFGTDGVRAVAGQFPLVDDFIQKLGYAALRELQEYAKSEHLKPQVIIAQDSRASGPAILAALEKGIRASGADVISVGIAPTPAVAYLVKHTGSLCGVVISASHNPAEFNGIKFFTNHGTKLPEELENSIEAEIESLQSVPAPKGVFTQDESLVRDYERFLMSTVDASLLKGTKVVLDCANGASSKVAVNVFAGLGMDVTVTAAKPDGTNINKNVGALHTEFMQQLTKQEHAFVGFSFDGDADRVIASDEQGRQLDGDNIIASSALCMKQAGELNGNKAVLTIMANLGCINYLKENGVEVELTTVGDKYVSEALEKENLSIGGETSGHIIFRRFANTGDGILSALQFLQFVKKSGHPVSWFADRWKKYPSKLKALAVTSKPPLESLDGFLPGVADIEKTMHGRGRVVVRYSGTEPKLRILVEGDEENMVNRVLDEVEALYRQKTEVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFA7</accession>
    <name>A0A1Y4DFA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57332">
        <property type="protein sequence ID" value="OUO57332"/>
        <property type="gene ID" value="B5F75_00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="310" mass="34030" checksum="28FD75543A6D6E2F" modified="2017-08-30" version="1">MNEFTAIIPAAGKGVRLLPYTANMPKTMICVAGKPILGHILDQVESLGIKKVVFIVGYKKEAIIEFVQSQYPHLEANFVEQPEPKGLGQAIYLAKEKVSGPCFILLGDTIVDGDLKPLVFGGQNAIGIRAVQDPSRFGIVELKNGKIVSFEEKPARPKSNLAIIGAYSFLDSAQLFSALEEVIRSGKTVKNEIQLTDALSVLLARGVEIHPVQMNDWFDCGTVEVLLQTNRLLLDRHHRIPAGLERNNKIIPPCWIADGVQAQNCTLGPYVSIAYEAQLTDCALKDAIVGPQTRLQNKTAEHTVLDKYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFF3</accession>
    <name>A0A1Y4DFF3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recG</name>
        <name evidence="9" type="ORF">B5F75_00955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57372">
        <property type="protein sequence ID" value="OUO57372"/>
        <property type="gene ID" value="B5F75_00955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="289"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="466"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="698" mass="79405" checksum="0B25929F66F661A1" modified="2017-08-30" version="1">MTATTQIQFLKGIGPAKAKLFERLEIHTVEDLLHYYPRTYQDRRLDTPPNEYNSDALVVFKGRVLRTQEIPARSVLIFKAFLENEKGEHVECTWFKRRMYRGFRFDPFGTLKKDFKMNQEVWVIGKRDDKNNFFGNKITVDEHYPAADALTKLHAGRLTPIYGLTEGLTNKQFRQFVYEALQTSSLEREPEVLPPDLLSKRKLLSAPQALKAVHFPNSLAELQNARTRLAYEEFLLLATAWGIKRTQTKILAKDYSYQIKKTLLTPFRQQLGFEFTNSQKKVINEIFKDLCSPRPMNRLLQGDVGSGKTVVALCAMLLAAENGYQAALMAPTEILAEQHFLTFKRLLSGLNVNIAVLTSSTKTAARKKILKELAEGEIDILVGTHAVIQDEVQFHNLRLAVIDEQHRFGVKQRSRLKEKTAKLDLLTMTATPIPRTLALAFYGDLEVSTLNELPPGRQPIRTESATSKLAYDRVREEVQKGRQAYIVFPLIEESEKISAKAVTEEFEKLKKVFPQFRLAILHGQMSQAEKENVMADFAAHKTDILVATPVIEVGIDVKNATVMVIENAERFGLASLHQLRGRVGRGEHESYCILVPQHPGSVAKERVDIICATRDGFKIGERDMQLRGPGEILGTRQSGELEFKAGDIFKDKDILYWAIEDRDALLSQDPSLTAPEHARFRQKLVELYQKDWHLIDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFF4</accession>
    <name>A0A1Y4DFF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57665">
        <property type="protein sequence ID" value="OUO57665"/>
        <property type="gene ID" value="B5F75_02505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="280" mass="30212" checksum="0234A68770F604E5" modified="2017-08-30" version="1">MTSKPIVVGLGEVLWDMLAEGKRPGGAPANVAYHAAHHGAEGWLISAVGQDALGDDLQQQLHAGGVQLEVARVPFPTGRVEVTLQQGIPSYRIVENTAWDHIPLTQAASRLLARADGVCFGSLAFRTAESRRNLSALLAGMPAETLKVLDINLRQPYYSKELLETLLGLCNALKINDDELKVLADYFNWPTESVCAELMRRYGLRFLILTAGAQYSNVYAHGTLSHLPTPAVQVVDTVGAGDSFTAAFVCAWLRGESLERAHQQAVQTAARACGHAGAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFG4</accession>
    <name>A0A1Y4DFG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56419">
        <property type="protein sequence ID" value="OUO56419"/>
        <property type="gene ID" value="B5F75_04285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="146"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="292" mass="32138" checksum="F0F152ED01D6A33F" modified="2017-08-30" version="1">MTPLLSAWICWAIVGLSPIAGKYAAGVISPALLVFLGTIIGVLYFTPWITKNHKWGELLSGETCWKFLFIGTFGTALPFTISLIALHYTTPGNAAILQQSELLYSLLFAGIFLKEFPSRQQLLGSALIVLGVLIILLKEQYTPRWTGDLLIVGSTWMLQAGSTVAKKLPKHLDHRVIAMARNLFALPALIGILAVMWGMKESFVLRPNLQMFSVLAYTGFLKYGLAMVVWYKAIRALDLSKVTAIYLSYPVLSLILSALLGLENITWHQAAGLLLTLAGAYWVSLTVKKEGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFL1</accession>
    <name>A0A1Y4DFL1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57432">
        <property type="protein sequence ID" value="OUO57432"/>
        <property type="gene ID" value="B5F75_01275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="157"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="311" mass="34794" checksum="E23C5C7BA3FEF23B" modified="2017-08-30" version="1">MLMEHNAKILLADDSHAIRFLVSEILTNAGFTVIEAEDGQEAIEKTYKENPDLLILDYEMPKKTGFEVVREVRSRTGYLHTPIIIFTAVTEKSTKLEGLGLDIDDYLTKPADEDEIVARVKLLLKRNKQKMDCNPLTRLPGNPSIQTRVEAEIASGRPFAVLYCDLNNFKSFNDKYGFEAGDRVLKTEADVIVHAAEQDPTSFVGHIGGDDFIVVCSFDKAEAIAQEITSKTDALAPTFYNEEDRKNGYMVSTNRRGEMEKFKFLSIGIGIVHNTKKPLTSFAMVSNIGSELKCLAKQHEGGSFYVLDRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFL6</accession>
    <name>A0A1Y4DFL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56479">
        <property type="protein sequence ID" value="OUO56479"/>
        <property type="gene ID" value="B5F75_04605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="499" mass="53870" checksum="CA7D823BDADCA49D" modified="2017-08-30" version="1">MQSIQQLGSAFVQFFSGPSVQSAYDLMNGFNTLVWGPPMIIILLFLGIYFTVRLRFLQKYTWPAMKLSVTKVESEGMVSSFGSLAVMIGATVGTGSIIGVTTAVAEGGPGALFWMVVAGFFNFAIKYCECMVAFKYRVKLPDGEYVGGPMYYLSNILKFKWLGLIFAVGTLLMGLTAGSALQSNSIADALREGYNFNPWYTGLFVAIATAVVVIGGVKRIAAYSEWLVPIMGSLYLLLAVIVLIMNFGKIPEAAVIIFKSAFTGKAAAGGAIGIGIMGLLQAMIPAVSAGVTRAVLATEAGLGSASIAAAAAKTRSATQMAIISATSVFWAIFICMLTGLVIILAGDWQNPNVYAANLCNSAFKTVPYIGTPILIFSLVIFSFTTIIGWGYYIEKALQFLCKGSNALIKPTRVLFILLVFAGGWIGTSFSWDFTIAESLLRTAEANNSTRFMWALAVFTMTMMTVPNIWALWCFRKVIIKTTRKNIKNIVGRKPKQSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFQ9</accession>
    <name>A0A1Y4DFQ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57482">
        <property type="protein sequence ID" value="OUO57482"/>
        <property type="gene ID" value="B5F75_01545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="61" mass="7027" checksum="5A33D7C42432C77A" modified="2017-08-30" version="1">MDNLIKQLEDYRLKNRLTQAELAKLLGVSYVSINKWLNGHTRPQKLQIYQIEQLISTGGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFR2</accession>
    <name>A0A1Y4DFR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56529">
        <property type="protein sequence ID" value="OUO56529"/>
        <property type="gene ID" value="B5F75_04875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="439"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="540" mass="59959" checksum="970286668CC25C3F" modified="2017-08-30" version="1">MIRRKDLYTALADSAFRFPDKIALVEAGTEKKVSYHELLMQVDRAADMFFEHGIRKGDRVAVAHRNAIDTVVANFGLYKLGAVCIPMNFMVTKPEEIEYILNNAGAKAVVTQAEFIRHYVKCLPQLPTVEYIFSTDEIPSSAAGNPKLQLFWEQIEKSTVHEETASANAGLEDLAFILYTSGTTGLPKGAMLTHGNLASNVISCAQIFKITDDDCFLCLLPMFHSFAWTTCVVIPMYLNLKVVIVANVMPASKWLGAMGAEKVTVILAVPQIYAVLSKEAKGLKRLYLRFWPFKNVRFAVSGAAPLTQEIKDRFEEKIGVPILEGYGLTETSPVVSVNTEELQKIKSVGPAIPAVSTIVLDDDGNEVPRNKEGELCIKGPNVFRGYWGNEKDTRDAFTEDGWFKTGDIVEVDDDGFIFIKDRKKDMIIIKGLKVFSAQVEAVICEHPGIEECAIIGVPDGRGGEFVKLYAVKKEGAQIDEAEFRKFLKTHLDNYKRPRDFEFVDALPKNALRKVLKRELRKDAVAKLAARGAAAAEEHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGA5</accession>
    <name>A0A1Y4DGA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57682">
        <property type="protein sequence ID" value="OUO57682"/>
        <property type="gene ID" value="B5F75_02595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="338" mass="37061" checksum="D73693B3E0C13FCA" modified="2017-08-30" version="1">MFTKTSLEKLAPINTVCLMILAATAATGVLVYTKTMLMPFVIALFISMVAGTLAGWLKQKWKVPYGLGLVLSFVAFLAFVVLSVLFISGSIESFVAGADIYSERLNDTLDWLLMNSQKFGVNINSQFVADTVSKLPVFNMLKSVGSTLVSILTNLMLITLFVIFIFMGKASADKPSLVGNIQKQISFYLLIKIFVSLLAAGFTWVVLASIKTELASMLAVLTFVLNFIPNIGPFISTLLPMPVLFLQYGFDWHILLALILLTTIHFIIGNILETKWLGKGMDLDPIVVIACLIFWALVWGIMGALLAVPMTAIIKIALERNETTKPLADLLGGKYAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGR4</accession>
    <name>A0A1Y4DGR4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Usp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56118">
        <property type="protein sequence ID" value="OUO56118"/>
        <property type="gene ID" value="B5F75_05720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="472"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="6">
        <location>
            <begin position="528"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="675" mass="74222" checksum="A7483FB893DD810B" modified="2017-08-30" version="1">MKQPSSSSAGASRVKKVVVLTTAMLTFIPFWKAAAVVLCDFGSSAFYAGGIAMRAFGPAFPWYILAVMLFSGLLLMLELEACSLFVRGGAYKIVREGMGDTAAKLAASALIFDFILTGPISAVTAGHYLCGLFNSFLEWGGAAIELPENVISVLFGLLVTGYFWRQNVKGIEESSSKSAKIIAFSLAVCFLLAIWSFITMALHGAHLPPTQLAFSQEALGWAGGIDWMQTIGLVGMLMAFGHSVLALSGIETLSQVYREIEYPKAQNLKKAAWLIFGFALLFTGGLTFLSAVIIPPELVATKYYDNLLAGLAMSMAGPNILKLLMQAMIVVCGVAMLSGAVNTSLIGSNSLMNRIAEDGILTDWFRKIHRRYGTSYHIIHVIAVVQLAVILVSRGNVYLLGEAYAFGVMWCFVFEVSAIIRLRWKRAAQKRDFMFPLNIKYENYYIPVGLILLCGFLVSVACVNLFTKQVATVAGLGFTAFLFAVFSLSERLNAKRANTMFEEGYRERINAQTVDDLKEAFSELDHPHRILVAVKNPENLYHLEEVLSKANAEDTDVIVLYCKPVENVLYRQDMRSAAVDEQEVFTAVIFLAEKYGLPVTPVLVHSNDAYYAIAQAAAVADAEEVVMGVSGRHGANPQIERAVMTWGAVKDHELKHPVTLRILWEGREVSYRFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH49</accession>
    <name>A0A1Y4DH49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57009">
        <property type="protein sequence ID" value="OUO57009"/>
        <property type="gene ID" value="B5F75_03950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="401" mass="45350" checksum="37201FF0C225B9F4" modified="2017-08-30" version="1">MTLMLFIRKKSFLQNKSEIRRCKNRETGVFSLNKLYNLYISLSRSERVKKPLKILCYILGAFLSVGIIALMVYQTRDSFVKIWQGVSTRYLFLSLLSSVLIYISMGLSLYEVLRIMGRRVSKGAAIGIALVSTTVNYVVSSLGVSGFALRAHLLNRRRVPFGMCVTASIVITVLLYFVLAVIILQGSVLMLFNSSATTMQILKNFSLIVVMCAVCAVITAFLFNNEWRSRWLRKIFRMINKVLYHVFRALIAKNKYDSFMDQLDEGIDLIHKKKKKLTMTIVYVCADWLFTILVLYFAFRAVGVHITAGVLVAGFAVGMVTTLIPILPGGLGAMELAMTAVYSQMGIDWDSALMAALIYRVVYYVIPGIISIFIYWGLQLSSPSSPRKKKLPKEFSHERTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHP8</accession>
    <name>A0A1Y4DHP8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR_21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56458">
        <property type="protein sequence ID" value="OUO56458"/>
        <property type="gene ID" value="B5F75_04500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_21" evidence="3">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="219" mass="23699" checksum="639951CAC2A6B9BB" modified="2017-08-30" version="1">MTKQNTSSVEQKDFLVSFLSGIIDFCKKNKKGVLTALVILVLAAAIGGGYAAHVKKVTQNSWAAYYSAQVALLSGQEQEGFALVDQLAKDYPGSDASQYALLMKADLLYSTENYAQAADVYKELLVSNNPTVSTVAALSLAAAQQAVKDYKSAIEGMNQFISNNPKNFALPQAYLTLAMSQELAGNKTEALNAYQHLADAYTQTYFGELAKQKLAELQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHQ9</accession>
    <name>A0A1Y4DHQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56468">
        <property type="protein sequence ID" value="OUO56468"/>
        <property type="gene ID" value="B5F75_04550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021868">
        <property type="entry name" value="Alpha_2_Macroglob_MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041462">
        <property type="entry name" value="Bact_A2M_MG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11974">
        <property type="entry name" value="bMG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17962">
        <property type="entry name" value="bMG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013096545" evidence="2">
        <location>
            <begin position="27"/>
            <end position="1884"/>
        </location>
    </feature>
    <feature type="domain" description="A2M_N_2" evidence="3">
        <location>
            <begin position="983"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="4">
        <location>
            <begin position="1200"/>
            <end position="1289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1884" mass="206509" checksum="077FCF09C69D51C5" modified="2017-08-30" version="1">MKHTRFMARFGALAAALLLPCGALFAAPALKVLSATPKGQLNYTGRQAVTVTFNQPVVALGEESAFSSDNCPITVTPAVKGSCRYSGTQTLLFEPEQDWPVATRFTVRLKAGFKSAVSGQKLAQDYVYNFTTALPQVNAVRPNNNERWINLYPTLYAVFNMPVDMSTVSNYVELSYMQEPEPTLSEKIGLSKTKRPAVKKTLPLIIRPISSLEYDKDFSYYQNKERIIAINALDTLQKGTQYTLTLKEGLKSTQGPLGMAKAYQSSFYTYPELSVVGELKDGCLPYTPSVNFSSPVRMRELYAAARVEPASAKREMSEQELNALGTDVVDSKTGAAYFRTPLAFLDLQPGQAVTVTLGKGLQDIYGNSLGQNYQLTVSNSGYCPAVDFSGGLGVLESYLSPRLPIDLMNTPSLPLRGARFNKENFVPFDQASSSYCAQKPLTDPTFSGNYTFKDVKDRTLKTFIDLSKFNPTAKDSIVFSQVKLTGKKYGDKGCWISSTDNITDVGVTFKTSPDNILLWATSLQTGEPMPNLTVELRGKENKILWTGSTDMNGLARAPGWSKLDVEAKSWSQPEIYAFVSSAGGDAVVSNLWNDGLQPWRFNLSYEYNPQREFVRSYLFADRGVYRPGETMYIKGVSRLLQDGAWRLPDVVRGTVQITDARGEEVLKKDVTVSSGMGTFDLSFDIPKTAATGSWSLSFEPQIKNLEDAPRAYYSFRVEAVEQADFKVNLRAETADYLAGQEASFAASAQYNFGSPLADAKAQWTLRREMAWFEPAGFDEYTFTPYFLREKESQENGKLLLNSSGVLDAKGALSFAARMPSVSFPTKVYAELGVQSPARQELFARTSVLVHPADFYLGSKLLAERAELGQPVQADIIAVTPQGKRTEASVTAKIYKEQWYSVRKTGLSGRLEWVSEKKVTELPTQTLEVSEKGAVLSFNPEEAGSYYVTLLSEDAAGRKVTGGFNVFVYGEGQAYWKQSDDDLLVLKQDKNAYKPGKTARIAVESPYEQAFALVTVEREGILDAWVTTVKGGADYVEVPVKASYLPNVYVSVTLVRGRSADPVTDKGLDLGKPQGKVGYVNLSVLPDSKQIKPVIKPNKKEYRPGEEVTLKITAKPNAKNMPAEVVVMVVDEGVLALTDYETPNLFDYFYGSRPVSVFTMDNRVYVVGQRNFGEKGENRGGGGSADAKLGGVDLRSNFMFTPYFNATVQTDKKGRAEVTFKLPDNLTKFRVMAVAMTADEFGSAETAIEVSKPIMVTSNLPRFARKGDKFSCGAVIYNYEDKKGDMTVTARAEGSIRLTGAAEQSVNIALGKAREVTWPCEAVADGPARVAFSVQAKTESDGVAAELTVSPVEKKQTLALYASTVSSQEELLDKPGNLNESADNRVTLSLASTALLNLKGSMVYLMTYPYDCLEQKMSKIVPVVTGAQLVEDFKLGDKTQLKAQVQDILDEVSQYQTAAGGYGYWKNSRPDPYVTAYALEVNYLAKKAGYTVQDKSLAKAAQWLEGAFSSKVQKAYSYSSLETETARAYAAYVLALYGKNVQSAFNNLYGKLGSLPLPAKAYLLKAAQAGGNTDAVKAKIAQSILNHIAYTPQAAYFDAPEEMPWLHMGNVKASALALDALLYAKQPFADAFKTASWMLTQLNAQGYWANTSVNAAAFMALNTYYQTMESVEPDYAASVKLGAKTVLEASFKGRTVDAKTASVPFAQAYGNGTETRLTFAKDGAGTLYYTLGQEYEPLSYQTPVDAGFTVSREITTLDGKPVSNIVAGERYKITLHVKNAASRHFVVVEDFIPAGFEIINTSLATESQEQAAALDTPQWNGFERDEKYDDRIAAFADYLPAGTHAYSYLVTASVAGTFAYPSLWASQMYEPAVFGRNATETIVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI90</accession>
    <name>A0A1Y4DI90_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_07050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56030">
        <property type="protein sequence ID" value="OUO56030"/>
        <property type="gene ID" value="B5F75_07050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012192791" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="58"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="332" mass="37519" checksum="FEECAF1ECF2A5381" modified="2017-08-30" version="1">MWKTIVLLTCLLGAAPVWGQVSVISVTDEDRHTRKEDFYHTFEYYITPTGEKAASVSKCQATRIGRRWFATAAHCVQQNCQNGCLIQMDLLEQPVSALARVTHSAKKPAVFVHPDFSPQKIVKNDFALIRLDLDRAPITYYRRAGGKQKNNLALTRAQFDAFLRQNLQASRQYRRIVSPEFPPLVLFDDGNYVIDRDLSVISIFGGKREIKPDPYPVYYVKALGFAYTHNFGIRKGMSGSGVMSNTGELVGIISANLTSVRGVGNKAARKEEYFMFPVFNAEIASFMESVMGSDYYKLDWKDAFPDFVRKSQRDFSPVVQAVEWVDTHTGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIN4</accession>
    <name>A0A1Y4DIN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycolate phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57529">
        <property type="protein sequence ID" value="OUO57529"/>
        <property type="gene ID" value="B5F75_01785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="218" mass="24117" checksum="AA66D99761072CFB" modified="2017-08-30" version="1">MNEARLVIFDLDGTLLNTIADLAAAANAALQANHFPVRTQAECQRFVGNGINKLLERALPQGHKTPQDVANMRPAFFAYYDEHLTDQTRPYPGVKELLVKLQAGGVKLAVASNKYQSATRRLIKHFFPEISFAAVLGQRDDVPVKPDPAIVEEILWASGAQKQNVLYVGDSDVDMQTAHNAGVRVCAVTWGFRSREELMSYKPDFMTDTPAEIADMVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIP0</accession>
    <name>A0A1Y4DIP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56798">
        <property type="protein sequence ID" value="OUO56798"/>
        <property type="gene ID" value="B5F75_02840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011817721" evidence="1">
        <location>
            <begin position="26"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="30"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="343"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="529" mass="58222" checksum="54F7AC4B8A88F495" modified="2017-08-30" version="1">MRLRKMMFLWALPLAAVCFCQPLCAEKLAVYHTSDIHGYYFSRADKSGQPHGGFAVLENVLLQEKEPFVILDSGDFSSGNKEANASDGRYSVELMNAAGKTPKNLSGQGYAALTIGNHDSDFGAETLGQMLGGFNGDVLSVNVEGLQIPGKQIQPYKIFNWNGKKVAVIGFSMDGPGMSGMELKKLSAADWEKLLQELQAAQPDAVLLLAHDSIADPRKPSQLMDVLTAAPSAADTIDVFLGGHAHLQHAQHKMGDNGPLFVESGSMLEGVSRVELDFDDETGQLTGVTSSYIALNPAKWGENKAVKEKLDQIEDKSLTRVFASVPVTLYKYPQGPDAAPDVAKMLADYMKKWLEPQEKVDFALFQLPGIRRDLNPGNLTGRDLAELLPYTEYVSTFNITGKKFKQAVEDSLKCNPDGKNYSMFAYSDNVYIEYKCKPGNKKHPVKVTKLLLNGKKMSGRKTYRAAAIGHIPDGYFEGAPFKITKNPQKKIYKKTSGELLFDIVEQLPGQTPAEKQFKAPQDLRIKQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIV2</accession>
    <name>A0A1Y4DIV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56868">
        <property type="protein sequence ID" value="OUO56868"/>
        <property type="gene ID" value="B5F75_03205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="219" mass="24993" checksum="0C548EC9CC26B823" modified="2017-08-30" version="1">MITTVIFDMDGLLFDTEPIYFECYKKAAAEDGLNFTYELFESCVGISREEAARFILQHFGPQTDMQKLHVRTGEIFEEYLANDGEIRFRPGAKQAVEFFYNRGLKVALASSNITRWVMFLLEKKGIKKYFSSVTTSDDVFRPKPDPEVYLKTAQKLGVDVSECLVFEDSVAGATAAISARMRTCVVPQIKKPTQFVRENAFKIYHSLEDIYPDMDELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ01</accession>
    <name>A0A1Y4DJ01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">pyrG</name>
        <name evidence="12" type="ORF">B5F75_03535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56928">
        <property type="protein sequence ID" value="OUO56928"/>
        <property type="gene ID" value="B5F75_03535"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="301"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="377"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="534" mass="59422" checksum="520D4DFCE4258CC8" modified="2017-08-30" version="1">MSKFIIITGGVVSSLGKGISGASIGKLLQLNGLRVNMIKCDPYINVDPGTMSPYQHGEVFVTADGAEADLDLGHYERFLDVTMTRANTNTAGSIYQTVIDKERRGEYLGATVQVIPHITNEIKKRFTAFENDTDVSIIEIGGTVGDIESLPFLEAARQLRLEKGPQNVICVHVTLIPYIAVAQELKTKPTQHSVNKLREVGIEPSMLICRTEKPLNQHLKEKLSLFCSVPAKAVIECADAKSIYHVPEMFYKQEVDKQIISMLGLKPTQEVDPKWFDFFNKALKPSKTVKIAIAGKYAEFQEAYKSVHEALKHAGMNNDAKVEVVYINTEKDTVEDKLKDVDGILIPGGFGGRGIEGKIATVKYAREKKVPFLGICLGMQCTVIEAARNLCGLHDANSTEFDPTTKDPVVDLTPQQKNVVYKGGTMRLGNYTADLKEGSLARRLYGKDQIVERHRHRYEFNPAYVKLLSEAGLKVSGWHEGVLPEIVEREDHPFFIAGQFHPEFGSRPLRPHPLFDGLIKASLKQKESKKAHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ21</accession>
    <name>A0A1Y4DJ21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56948">
        <property type="protein sequence ID" value="OUO56948"/>
        <property type="gene ID" value="B5F75_03635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="48"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="168" mass="19245" checksum="274CC257D576548F" modified="2017-08-30" version="1">MQRVPYNFNAQKNLDILSKAAFLTTKSGNKINTMVIGWGSLGVMWRLPIFSVMVRQNRFTHTLLEKSHEFTVTIPYGDVSHLIPVCGERSGRDIDKLAACGLKTLKGQKIATPVLDLPGMHFECSVVYNRLMGKEHLNKALEELWYNKEPDDYHMFYFGEILDSYITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ22</accession>
    <name>A0A1Y4DJ22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57669">
        <property type="protein sequence ID" value="OUO57669"/>
        <property type="gene ID" value="B5F75_02525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012101951" evidence="1">
        <location>
            <begin position="26"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="403" mass="45097" checksum="D56145C68898111D" modified="2017-08-30" version="1">MNIKKTLAFFGIVALLCGGTTPVFAQKDLTKFLKQLWGPKNLFFNRSPSLKQTFPKINWQALDNMAFAQVSTQQVLSAATPLFMPKVSVDVPRPLLPAPQKIKRAVFTLQYDPKTHGKGSAFAVKIDGQVWGVTARHVLDDIGRSPYMSLKTPAGQELFFQVFSVREGNVHGADIAVFRIPPQALDYITPLQPDYVLPTPEEQVQSAGFSHGNFGWFPRVDVLFASNHRILARYENFPVRSGYCGSPVLKNGKVMGVFVGIMPQELAQTAAWFSLVSNSFPTPIHSFTQIVPISWVLRLVRQEKSGLPIESTVPVKVLGKTIAWLHPDENIVSIQQMRNGNLIKTIPAYPFMNYSHLEAFLEIQPLDRIYVTIQQGDRSSSRKRIFVYALDTASGKVTHTERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ47</accession>
    <name>A0A1Y4DJ47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ORF">B5F75_02635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57689">
        <property type="protein sequence ID" value="OUO57689"/>
        <property type="gene ID" value="B5F75_02635"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="102"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="327"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="402"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="402"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="104"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="487" mass="53810" checksum="CBA6C08871A57434" modified="2017-08-30" version="1">MSSSIVLQKAAENGLTVTGLTFRSQDVRPGFVFFALKGANADGNLFIDDALARGAGMVVSMFAPAKPCPALYYQSADIDRDMADAAYEFYGRPSDAMHMTGITGTKGKTSIAYLLESILTAAGHKVGALGTVNYRMAGQVLSKAPNTTPAALVLFELLARMKNGGCDSVVMEVSSHALELQRVRHIWYDTAVFTNLQRDHLDFHHTFENYFKAKQKLFENLADPHNFKPNRVAVINADDPYGKRLLELLQGRVKTVTFGLESEADFKAQDIQETLEGTSFSINGTPMHIRLLGRHNVYNALAACAAAWVHGADEAAIVRGLAALPGVPGRMERIDEGQPFSVFVDFAYTDESLRRAFDTVEPFKKGRVLVVFGCGGQRDRTKRPLMGNTACSRADRVFLTNDNPRCEDPQQIFNDILAGMKDFSNYQIIPDRAQAIESALKEAQPGDIVIIAGKGHEDYQLVGTQKRHFSDQETVRTWLQKEKKKYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ64</accession>
    <name>A0A1Y4DJ64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OstA-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56988">
        <property type="protein sequence ID" value="OUO56988"/>
        <property type="gene ID" value="B5F75_03835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013277477" description="OstA-like_N domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="2">
        <location>
            <begin position="95"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="32998" checksum="C18D6C1F27B320B9" modified="2017-08-30" version="1">MKHFSVLFVLLAAAVLASGCKTVRIEGPAVSVPAAKPRLEQAKTSLKNKKEAAITLPPTLGGLISSDRWLIHNAKQQEEFIGHVSYANDVYTFRSDYALSDRPKNRIFVRGNVYLKQAKPGEPVYEAYADRGTYLYQKKTGDLLADPGKEIRLIYSEKGQAPVTAQAQLAYFDLEQGRFVLNKDVRVQRPTPQGMQTMSAQKVTYRQPQNLLTLEGGAQVSDEQRTLAAQTIIYDGTKNYSYAYGSRPLLTGSSEQGTFAIIADKVQSDNEGNKITMDGKVQGWLVSPAINEAAVNDKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJE2</accession>
    <name>A0A1Y4DJE2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_04210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57058">
        <property type="protein sequence ID" value="OUO57058"/>
        <property type="gene ID" value="B5F75_04210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="311"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="415"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="365"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="631" mass="69659" checksum="A12E741F2B6202BA" modified="2017-08-30" version="1">MHIKRFNGLFAKAVLVLILISIVPVVIIAYHVMGVDSRILKNEILQKQQTVASRLASVARAHINRKAQLFSIFVDLHTDFGGHDFINEQDLKYLLARNPAIVYLAVLNPSGVQLFSAGTPAGTVNYAEMLPHIVEVCVQRGKDYISEVYQRKGGLFALLAFPVRQHLGDTRVSGVLVAEMNLKEMGESLSQAYPLDMNAIIATEDGKIISYNGAPDGLAQEPQPEMEAKVQAINAQLGDEPSGEVRLPDGDSVLVAVANLSLPGWKVYVDQPANVAAQLFVESTFHSFWDVIVLVLAMLAFVLIVSYWVIKPITRPLERLREAAVKQREKEDYVVKKEDVEIPNNEIGELAAAFVDMSGTLHTRRQELLRAQTELAQVNQALEKRVEERTHELKAASKELVKAERLAAIGQMASIISHEIRNPLAVISNATRLIKMLVASPDPKLTKQFGIIDSEIKQANSIISEVLGYARTRELMLTTVDLNSYLRELLLSYPFIPGITLKDELDPESVRIKVDAEEIKQAIRNVVSNAIEAMPNGGTLTVGTKIGRRLVCIYIADQGTGITEEVRHKMFAPFFTTKARGTGLGLAVVGKAISRHKGKLFIHSVPGKGTCFQIYLKIYRKPGDTNYGEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJR7</accession>
    <name>A0A1Y4DJR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05145</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56580">
        <property type="protein sequence ID" value="OUO56580"/>
        <property type="gene ID" value="B5F75_05145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_1N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="74"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="169" mass="18460" checksum="F26B98CBA492443F" modified="2017-08-30" version="1">MTETYISYPSPLGELTVAGDGKYITRVVFPGIRRGSSLPRQNSPLLQEACRQLDEYFAGRRFVFDLPLRAAGTPFQMRVWKALEKVPYGKTCSYGQLAAWAGNPRAARAVGGAVHVNPIAILIPCHRVIGADGTLTGYGGGLWRKEFLLQLEKSFLPRIKNPAEGPGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJT6</accession>
    <name>A0A1Y4DJT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56600">
        <property type="protein sequence ID" value="OUO56600"/>
        <property type="gene ID" value="B5F75_05255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007739">
        <property type="entry name" value="RgpF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05045">
        <property type="entry name" value="RgpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="294" mass="34239" checksum="312ACAE8244217D8" modified="2017-08-30" version="1">MVFTEMKPTAVHLHLYYMQRWPEIRKYLEHLDAGEYHLYVTLSQENAPLAQAIKAFHPQSTVWQTPNRGYDVGPFVDFLQKVDLSRYDLILKIHTKNKSGLQKTWINGRCITKKRWVDLLMNALLGSADIWRRNLEAFAADPRLGMISSRYLITQEPECSDYLRPEIERVLKQMGLCVPDKITFAAGTMFLVRARLLEKIKQSFTAADFPPTDASVQDGTLAHVFERVFGCVVEAQGYAVKGFDKRRWFEMQAKLYRVSRFFYSNDITRSNHQLIKICKIPVYYKNLNHHPRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJY3</accession>
    <name>A0A1Y4DJY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KilA-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56640">
        <property type="protein sequence ID" value="OUO56640"/>
        <property type="gene ID" value="B5F75_05470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="293" mass="34010" checksum="F8CE21C9D69BC047" modified="2017-08-30" version="1">MTPKSTTRELTVQNITFRNISGEKGSEYICISDIAKKFTTNSQGIDVLIHSWLRNKNTIEFLGVWESINNINFNPHEFEGIKNESGVNRFNISVKQWVERTNAIGIYAKTGRYGSGTFAHYDIALEFASWLSPELKLYIIKEFQRLKYIEAERAKVEWQTGRFLAKVNYRLQTDAIKNHILPLINVPKWKEGFEYAKEADVVNMAMFGKTAADWRRENKNRKKTENIRDYASAIELAIISNLEHKNAELIKQGLSQFERLRLLTEQANEEKRILNKNLPEQGMFELPDQTKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKA9</accession>
    <name>A0A1Y4DKA9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpmI</name>
        <name evidence="14" type="ORF">B5F75_00880</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57358">
        <property type="protein sequence ID" value="OUO57358"/>
        <property type="gene ID" value="B5F75_00880"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="12">
        <location>
            <begin position="3"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="13">
        <location>
            <begin position="81"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="151"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="261"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8 9">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="409"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="518" mass="57019" checksum="2F054B8A9AB298B6" modified="2017-08-30" version="1">MNKVVLIIRDGWGDAKAGPHNAVTTAKTPNMDKYLAQYPHTQIEASGEQVGLPAGYMGSSEVGHLNMGAGRIVIQELKRLKDTIEDGSLFKSAAFSACIDNCLKNNKPLHVMGLVQDEGVHAHQDHLFAILKYAAEKGIKNVYVHFFSDGRDTPPQSAVGFIRTLEDKMKEYGVGQIATIQGRYYAMDRGEDWSLTDKAYNLIVRAEGLHGTTAEEVVLTDYKTMKTPDGGPMVDEYIPPTVLGDYKGMEAGSSVIFFNFRQDRAIQLTRAFIDDNYPGKNRGPRVPCVYCGLTKYYDAFPYNALPSMTDGGGMNNLLGEVISKAGLKQLRLAETQKFKHVTSFFNGKLIKPYPGEDRIEIKGRFDPATFAEHPEMEAYFVKDEALKQIATNKYDFIVINFANCDMVGHTGNFDSVVKAVEVVDECTGAVTEAALAAGYTVFITADHGNAEEMWDEKINMPKTAHTTNLVDFVYVSKDHKNAKMAATGNLGDIAVTVLDVMGLKKPADMTAKSLIVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKD5</accession>
    <name>A0A1Y4DKD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ORF">B5F75_01035</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57388">
        <property type="protein sequence ID" value="OUO57388"/>
        <property type="gene ID" value="B5F75_01035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="3"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="338"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="256"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="487" mass="55493" checksum="97511D9E8E57B6F8" modified="2017-08-30" version="1">MTVRVRFAPSPTGFLHIGGVRTALFNYLFAKKNKGTFLLRIEDTDEERSTQASTDAIFEGMQWMNLNWDEGPMPDGTNKGPDAPYYQAQRADMGIYKKYIDQLLAEGKAYKCYCTEEELEENRQKCLAEHRPPKYSGKCSHLTEEQQKELEAQGRKYVIRFRMPQEGDVEWDDMIRGHVKFASKDLYDLVIQKTSGYPTYNFAVVVDDHLMRMTHVIRGDDHISNTPAQIQIYRALGWKEPIFAHLSMIHGPDGKKLSKRHGATNVVEFRNMGYLPEALKNYLALLGWATPDSQQLFAPGELEEKFDISGCQPSPAVMDPEKLNWMNGEYIRATPLSRLTDLALPFIEKAGINVSGVDRARLEGIIGLEQEKYKLLTEIPDLIRFFFEDPVFEQEAIDKVFSKPEAKKVLEGMIQVYGNLTDFTETNLETAARAYAKENGMKAGQIFHPVRVAVSGRTHGPTLFKMLEYMGKDTVLARLKNALQYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKL4</accession>
    <name>A0A1Y4DKL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_03060</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56840">
        <property type="protein sequence ID" value="OUO56840"/>
        <property type="gene ID" value="B5F75_03060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="9">
        <location>
            <begin position="119"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="296" mass="31692" checksum="395C893FA57F8E5B" modified="2017-08-30" version="1">MANDSLRRLAVEFKNFLAAQDEDEFISAAAPSRAAAVASGAPKEPLPRMPEGETLTVEFPRAQQAAAAVQPEPVSVTDVSASGNVMNTAQKTAALAELAETIKNCTRCPLGSTRIHAVPGEGNVDAELMFVGEGPGYDEDRQGRPFVGRAGQLLDKMIAAMGLSREQVFIANIAKCHPMTDPLHPEKHGNDRAPNAGEIACCRKYIEQQIAIVCPKYVVALGGVSAKALIADAKSLGALRGKFYDLHLDSVTLPRPVQIIATFHPAALLRNPGWKKDAWIDLQMVMAKLGLKAPHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKV1</accession>
    <name>A0A1Y4DKV1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56930">
        <property type="protein sequence ID" value="OUO56930"/>
        <property type="gene ID" value="B5F75_03545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="173" mass="19457" checksum="72143DC67642D692" modified="2017-08-30" version="1">MLKNMLAKGFTLTELMAVVIIIAILSGVALGSYKKAAERSHFTEGLVAGHTVLEAVNRYYYDNPDLSDSERKRPKADYLDIGLSNARSCTINPNKDYCLRTKYFEIVIQTWGVQVNRVQNNAVKDYYFYLYPEYASGRYPDQCISRSATGHDLCVTMGYTNCSGSGSYYSCTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKZ2</accession>
    <name>A0A1Y4DKZ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57598">
        <property type="protein sequence ID" value="OUO57598"/>
        <property type="gene ID" value="B5F75_02155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="13"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="128" mass="14312" checksum="737D02478AD233EB" modified="2017-08-30" version="1">MQKTIFYHDTDCGGVVYYANYLKFFEEARTLYMAEKGFSVPALMQRGLYFVVARQEVEYKFPVRYGDVIDVSTRVLEVSDIKIVFENIITNQNGRLCTKGKTTLVCVNSSGMPTPMGADVKAAMAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL15</accession>
    <name>A0A1Y4DL15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56111">
        <property type="protein sequence ID" value="OUO56111"/>
        <property type="gene ID" value="B5F75_05685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041354">
        <property type="entry name" value="4PPT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17837">
        <property type="entry name" value="4PPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4PPT_N" evidence="3">
        <location>
            <begin position="33"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="105"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="206" mass="22961" checksum="42E4E1FC2E7E442E" modified="2017-08-30" version="1">MSCQIKEVDLNRLPPADEILSERETAFYQTLRFPKRRVEWLGGRFALKELVHAQTGAPMREIEVLPQPAGKPVLRVAGEKSDLAFSITHSQGWALAALSAEEPFLGIDLEKIEPRLDAWAKDFFHPSELTAGGERFLTALWTQKEAVVKLLGTGLCLNSYDVRCIDGKTFFFGPAQAVYARLGRPRITLQTSERIAGFMFTVASGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL47</accession>
    <name>A0A1Y4DL47_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiol peroxidase</fullName>
            <shortName evidence="2">Tpx</shortName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peroxiredoxin tpx</fullName>
            <shortName evidence="2">Prx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tpx</name>
        <name evidence="4" type="ORF">B5F75_02420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxiredoxin family. Tpx subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57648">
        <property type="protein sequence ID" value="OUO57648"/>
        <property type="gene ID" value="B5F75_02420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03014">
        <property type="entry name" value="PRX_Atyp2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00269">
        <property type="entry name" value="Tpx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002065">
        <property type="entry name" value="TPX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018219">
        <property type="entry name" value="Tpx_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01265">
        <property type="entry name" value="TPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="20"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="2">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="169" mass="18516" checksum="8ACAA6CA6FD01D72" modified="2017-08-30" version="1">MNTPKITFNGLAVSLSGHTLQIGDKAPSFQLVGNSLEPVSSDRFAGRVLVISCVPSLDTPVCSLETRRFNQEAAALPGDVTILTVSRDLPFAQARWCAANGIKQVLTASDYRNFGFAQDYGVLLEDLGLLTRAVFIVDKQGIIRYIQFVPEVTQEPDYKEVLAEIQKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL85</accession>
    <name>A0A1Y4DL85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldo_ket_red domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56181">
        <property type="protein sequence ID" value="OUO56181"/>
        <property type="gene ID" value="B5F75_06075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="305" mass="33061" checksum="C27EEF0BAF0DBA2E" modified="2017-08-30" version="1">MKYNRLGRTDLHVSAVGLGGWALGGATDWGATEETDARRTIFAALDAGITLFDTAPIYGESEVFLGRALKGRRPQVVLATKCGLVKNGSWTDHDLRPQTIISQLEQSLSRLQTDYIDLYQIHYPDPRVPLEEALAVLIRLREQGKIRYIGLCNAGGQEISAAAGQAVCVQNEFSLLHPQKGRAVFAACEKLHLGFIGYGTLCGGILSGKYKKEPNLRRADARNYFYKCYRGDAFASVYQTVLRVKEAAQKKGCAAASLAGAWALAHPQVSCVLTGARTVQQALQNAAAADIAVSSAELKFLEEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL99</accession>
    <name>A0A1Y4DL99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsR</name>
        <name evidence="5" type="ORF">B5F75_00855</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57708">
        <property type="protein sequence ID" value="OUO57708"/>
        <property type="gene ID" value="B5F75_00855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="77" mass="9035" checksum="3D884B7D23274E59" modified="2017-08-30" version="1">MGKKRFESRRKVCKVCAEKIDNVDYKNFQFVKSFTMESGKILSRRITGTCAKHQRQITKAIKRDRNLAILPYSLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLF2</accession>
    <name>A0A1Y4DLF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56241">
        <property type="protein sequence ID" value="OUO56241"/>
        <property type="gene ID" value="B5F75_06380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825077" evidence="1">
        <location>
            <begin position="23"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="40377" checksum="FA95480A950E0C9C" modified="2017-08-30" version="1">MKKLFVLAFAAALTLSACSSFRIGPKGEGEYVEAESLVPYDENNLKQMKKDGILAAQRAAVEKVAGIFISSATTVDQAQLVEDKIVSKTAGFIRRSHVQKSYRKGDEYYTKIKAMVLVKDIGDIIKQSEADAFAKKTNILITSREMTGDDISLRQDCKQAIYRALKDQPFALINGDNLSQNNIENPNPTIDQARQEGARFVIMADVQANPLVALPGTVSPFKSYRARANIRAYATNNYAVVAEGAEQLSGLDPMDEIASQKAISAACEAAAKQLVEPINSAINSAKVFDVTVKDIGNIERLKQVQDILRDLREIEDFNLVRYANSSAQFEISANIGTPEELAAKIIRKYNINFTVVSITPNALVLSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLT6</accession>
    <name>A0A1Y4DLT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="7" type="ORF">B5F75_06975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56351">
        <property type="protein sequence ID" value="OUO56351"/>
        <property type="gene ID" value="B5F75_06975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="263" mass="28154" checksum="03A333F37FFFD7A2" modified="2017-08-30" version="1">MTEEIKNAAGAQEATPVAEAAKAETVKEAPATFRFVIGEKVGMTQLFDEKGNLHGVSVVKAGPCKVVRVRTQEKDGYNAVCVGFGEVKENKLNKPELGYFKKANVAPVKHMKECRVADVNGFEIGQVISLEKIFKPGDYVDVQGKIKGHGFAGAMKRHGFAGQPDSHGASDRTRAPGSLGSRRSLGKVLSGQRMAGHYGTTTHTVAKIEVVKVDNENGLLFLKGSVPGARGSIVSVLETSKFKKHYVAPQQHKVSASKAANKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM54</accession>
    <name>A0A1Y4DM54_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57370">
        <property type="protein sequence ID" value="OUO57370"/>
        <property type="gene ID" value="B5F75_00945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="458" mass="51535" checksum="B11EFBCE3C769AF6" modified="2017-08-30" version="1">MRDFDQPLKNNSPAIAAPAMGARYLMPKILAGQPIRIYVSVSQEKENRLDKYQTIIAENYNKWFTETASIIQANKRQQEFGDILPLLQKGIQVNFVNREEEADIVFFIVPFKTMQEHCGAGAGGCYFRVESPGGKPRIYLPEDHFWLKLFSAGKVSTSSIGLHEIGHSLGLSDQYEEARDANTHDRYSSMRSGKGTMKDNSSISCDEADGIINLIDLTRHTVRGAESGWKSLCPRSDEFYVRGQSASKGPFLIEQKDHNVFVLHTYKQGKRVASQTYTFQKQGAFFPTVFSEETVLKRDALGRPVKSTGPNGEDIYYSYQYEQYLRLVVQGKEAVLAEFNGAAGKGRRKIRYKTVLFNQNDRLVKATAAYGRNKAGSVEYQEATPQAKSLLYLSFNLDEKGNISQKYVRRASRQKAAAAALPAALGGNKIRSSVEKSVDESRLEQIQNQLIKWFKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM77</accession>
    <name>A0A1Y4DM77_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LL-diaminopimelate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23988"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="EC" id="2.6.1.83"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (aminotransferase route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.83" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56501">
        <property type="protein sequence ID" value="OUO56501"/>
        <property type="gene ID" value="B5F75_04720"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010285">
        <property type="term" value="F:L,L-diaminopimelate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01642">
        <property type="entry name" value="DapL_aminotrans_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019942">
        <property type="entry name" value="DapL/ALD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43144">
        <property type="entry name" value="PTHR43144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03542">
        <property type="entry name" value="DAPAT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="6">
        <location>
            <begin position="35"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="45237" checksum="D7BC34766ACA3DB8" modified="2017-08-30" version="1">MILLNENYLKLPGSYLFSTIAKKVAAYQQEHPNEDIIRLGIGDVSRPLVPAVVEALHKASDEMGRAETFRGYGPEQGYAFLREAILKHDYLDRNIALEADEIFVSDGAKSDVANFQELFDVSCKVALQDPVYPVYLDTNVMAGRTGNFENGRFGGIVYLPCTEENGFIPDLPRERVDLVYLCSPNNPTGAAMTRSELKKWVDWAAQHNSVILYDSAYEAFITQPDVPHSIYEIPGAQKVAVEFRSFSKTAGFTGTRCAYTVVPKALQVYDRAGKPHALNALWLRRQTTKFNGVPYIVQRAAQAVFTPMGQAQIRSVIEVYQKNAQVILQALQAAGLQAFGGVNAPYIWLKTPNGIDSWTFFDRLLSKARVVGTPGVGFGACGEGYFRLTAFNTPELTQAAASRIAHLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM99</accession>
    <name>A0A1Y4DM99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_04830</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56521">
        <property type="protein sequence ID" value="OUO56521"/>
        <property type="gene ID" value="B5F75_04830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="8"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="144" mass="15883" checksum="14E0F3CA26F817FA" modified="2017-08-30" version="1">MRKPLTKAEETALLDAAQAARENSYSPYSKFKVGAAVLTEDGRIFTGTNIENASYGLTVCAERNAMFAAVGAGQRRMRALALITQKLPGMAFNSPCGACRQVMSEFMPPNTPILIAVLDNNKRTVYRKQLRELMPFPFDKFSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMB5</accession>
    <name>A0A1Y4DMB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57430">
        <property type="protein sequence ID" value="OUO57430"/>
        <property type="gene ID" value="B5F75_01265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="230" mass="25409" checksum="AAAAD22B7D147861" modified="2017-08-30" version="1">MNIYADNRMLSLGLVGGTVSRHAGNMRTADAQAAVYQQLNIPAKQILHFHQTHSDRIIRIASDADALAFQNQPEQEADAWLFSCGGWGAAILTADCVPLFLWDETASVFALAHCGWRGVVGQLPYKTARAMKDAGAQGTLYGWLGPHIQSCCFEVQQDVAAQFSAQSVIHKDGKIFVNLNTEILLQLQLAGLNAADVKTPYYCTCGDKENFFSWRRDHVKDSLLSFIYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMY8</accession>
    <name>A0A1Y4DMY8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="2">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="2">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">murQ</name>
        <name evidence="4" type="ORF">B5F75_02585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57680">
        <property type="protein sequence ID" value="OUO57680"/>
        <property type="gene ID" value="B5F75_02585"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00274">
        <property type="entry name" value="TIGR00274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="3">
        <location>
            <begin position="58"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="298" mass="31522" checksum="ECEB2D19E9CD4660" modified="2017-08-30" version="1">MKPVNLNMIATETRNPNTMDLDKSTPRQIARKINREDFNAARAVQAANKEIAAVMVMAAHAYARHKKIIFIGAGTSGRLGILEAVECVPTFGTKPSQIIGLIAGGKKAVFRSQEGAEDDARQGAKEIARAAKKDDLVIGLTASGRTPYVLGALKEAQKIGAGTALISCNPQALCPHAQVHIALPTGPEALCGSTRMKAGTATKMALNAITTGAMTLCGKTYGNLMIDVQPTNEKLVARAIRLICTVAGTDEKTAAKLLQAAGKNVKTAVVMHRKKASKKEAEKLLKKQNGFLTKVIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN97</accession>
    <name>A0A1Y4DN97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56871">
        <property type="protein sequence ID" value="OUO56871"/>
        <property type="gene ID" value="B5F75_03225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013277484" evidence="2">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12232" checksum="546BAEC4278A3BA6" modified="2017-08-30" version="1">MKKNIFFLAAVAVLAAACAGNPPAWWNPGNAYSSGTAAESSRSETSGRVEMRTPAQQEVYIPQEVDIAPLPDESYEEMILTPLQDEETENDSGESSAQSAPTETTFLPPPSVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNA7</accession>
    <name>A0A1Y4DNA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acpP</name>
        <name evidence="11" type="ORF">B5F75_03285</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56881">
        <property type="protein sequence ID" value="OUO56881"/>
        <property type="gene ID" value="B5F75_03285"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 7 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="81" mass="9133" checksum="0A68A072A377BB75" modified="2017-08-30" version="1">MSVENVQERVKNIIVDQLGVEADQVKPEAQFVNDLGADSLDTVELIMTLEEEFNIEIPDEKAEKIKTVGEAIEYIEQNAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPF5</accession>
    <name>A0A1Y4DPF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57271">
        <property type="protein sequence ID" value="OUO57271"/>
        <property type="gene ID" value="B5F75_00380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="18688" checksum="3DA0A8C154504356" modified="2017-08-30" version="1">MERAMKKGFTLIELLTVVLIVAILSGVALPQYRKVVEKAHASEAQAMLRTIYDSSERLAGEFGFRSYAALVAQKGQTNYSFPRMDMFDSSNLPTGCSLVDSNRTLQCSRFSYTALVNENGVAYVKAEKRTDPYKGVSFYFDRENQQLYCKEPDASSEACDIFGLDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPS1</accession>
    <name>A0A1Y4DPS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_00895</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57361">
        <property type="protein sequence ID" value="OUO57361"/>
        <property type="gene ID" value="B5F75_00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="288"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="358"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="569" mass="63456" checksum="16D63EE578478C31" modified="2017-08-30" version="1">MSLFSKLFKLFLAVVLMPLIPMILLLTYYQVHLKNNILETHANLAQIVSSSMNQHIEDLTWRLAFAPQVTQALRKKQNPQPILQEALNANPDFLMLAVISPKGKELYRAGEKQILKQIPALDLSQDPSLPELAKTPRLSVSSFDVVAGRPISEFIYPLSNGDFLYGIMSFFGFLSRVQEQRIGLTGRIYIVDQDGAVYANDYQYKPAFDAETLKNAFASGNQLIKNLKTPRETYVGAFSASPILGAYVTVLQLKSEAYRSIYYTNIIIALFLLSIATLAYFGALTFAERLGEPIGALAHAAQEVSNGNLDEKVDEEIGWGEFKQLIKAFNQMTADLKDYQVLQLQAQVSEMKEQVFRSVAHDLRAPLLGLQGYLYILQSGKVSEEEKKNYLEMMSQAARNLSSLLEDVLDVSRVQAGMMTPKKESVEVAALFKNVTDTLEPTAREKGLELTAETEVDRLPADPKLLQRVIMNLVSNAVKFTDKGFVRIRAVQDEKAYYLSVQDSGIGISAQDIKGLFQKYHQIRSDRPGYGLGLFISRQIVQAHGGSLDVTSEPGKGSTFTVCLPKERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ92</accession>
    <name>A0A1Y4DQ92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.136</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ADP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nnrD</name>
        <name evidence="7" type="ORF">B5F75_01795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57531">
        <property type="protein sequence ID" value="OUO57531"/>
        <property type="gene ID" value="B5F75_01795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="199"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="301" mass="31807" checksum="53532B1E2BC090F1" modified="2017-08-30" version="1">MKQITRETLSAFLPRREKTAHKGSFGRVLAVAGSRSMGGAGFLCAKSALTAGAGLVFWALPQSIQPAFAAALPEAITLPLAQTADGLLAEDAWTDLLDFIREHRPSLAVIGPGMGQSPLVDKLLFDLSLPLVVDADALNALARRPHWEQHWPKDRPCIFTPHPGEMARLLKEPMAQTQEERLHQVQELCRKTGGVTLLKGCGTLVCVPQAQTPQVWQNTTGGPALAKAGSGDVLSGVIAGLWAQLGTAQGFDAASAAKAALCGVYLHGLAGDLAALKRSDFGVLARDTADALPQAFLEVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQA7</accession>
    <name>A0A1Y4DQA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RHH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57551">
        <property type="protein sequence ID" value="OUO57551"/>
        <property type="gene ID" value="B5F75_01900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="62" mass="7226" checksum="54348789AD3BCC88" modified="2017-08-30" version="1">MIFNTPMCYNITMEKQTPKKTNPTIAFVATPEIVQALEKRSKTEERSISWLIRKALEAYLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9K6</accession>
    <name>A0A1Y4D9K6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000009">
        <property type="protein sequence ID" value="OUO55947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55947">
        <property type="protein sequence ID" value="OUO55947"/>
        <property type="gene ID" value="B5F75_07240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO55947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="316" mass="33461" checksum="3924E0835E8984AE" modified="2017-08-30" version="1" fragment="single">SRAVTRQMSLDPLKLTDIVATGLNKKSTAYASINYVPTEASKVYWEIYTPGTSFANAGTPSNLVTDSSTPTGTGPTPVGGTLVYRSEEDRTARMNFTSKWDGLCGLNTTMTLSIPQGATYPANAVDDNGNSLAGQKCNAGKVCSYHPNGCMRTYAFNETMSDGTTCANTNGCTQTFNYGAPMPDGNYVYVLWAEIPYNGKYFNAKLNKTPNFIAGGTCGVPVGGIVAVNEGDGVCFTGVKTQNYSVGQIAIERGLVDITIQPVSYSTVGSSPTAYGLDPFIFKYSVVRDSTVVARVENAAGVAVKHLTPEEGVTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9V4</accession>
    <name>A0A1Y4D9V4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmG</name>
        <name evidence="5" type="ORF">B5F75_07015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56024">
        <property type="protein sequence ID" value="OUO56024"/>
        <property type="gene ID" value="B5F75_07015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="52" mass="6070" checksum="3F3F53A76776CFF8" modified="2017-08-30" version="1">MASERLTIALICTECKNKNYYQVRGKKKEYKLELNKFCKKCGKSTKHKEGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9X5</accession>
    <name>A0A1Y4D9X5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">B5F75_07065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56057">
        <property type="protein sequence ID" value="OUO56057"/>
        <property type="gene ID" value="B5F75_07065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="103" mass="11416" checksum="B47053E9AA780C77" modified="2017-08-30" version="1">MYAIIETGGKQYWVKPGQDLQVEKLDAKAGESVELKVLWAADEEGTSADAKAGNTAKVTAQVVKHLRGPKILVFKKRPKKGYERTIGHRQDLTQIKITDIQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAK8</accession>
    <name>A0A1Y4DAK8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56257">
        <property type="protein sequence ID" value="OUO56257"/>
        <property type="gene ID" value="B5F75_06460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="162"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="337" mass="36605" checksum="0404421B462B196B" modified="2017-08-30" version="1">MKVSIFVGGNKTFTASRLGVKLGEELARKGLEVTLRAVKGKVKSKDSAVILQEYAATAKPKTLAAALKKDQADFVISLMNLTGCQAALEAGVPFVYAENEGFKEDKAVKDKKAILKKAKQVLVIKTTEKPLNKKAYAGLKVQEVTNPAVWVEHYNYNKPACFKKENNIVAVGKFAKESGFENLLKTWARLAPAHSTWHLTIVGDGTGKAALAKFVAKNNLQDSTEIVTDDGDVYSLLRNADIFAYPALNPANADILLDAMASKLPCVACESEPVTDLVANGINGVIVNAGEEEPFTVALDDLMVNWGKRVGLAVEASKLKDRYPFEDFVRVFAELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAR9</accession>
    <name>A0A1Y4DAR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MurNAc-LAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56317">
        <property type="protein sequence ID" value="OUO56317"/>
        <property type="gene ID" value="B5F75_06800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012854">
        <property type="entry name" value="Cu_amine_oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036582">
        <property type="entry name" value="Mao_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07833">
        <property type="entry name" value="Cu_amine_oxidN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55383">
        <property type="entry name" value="SSF55383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013051135" description="MurNAc-LAA domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="3">
        <location>
            <begin position="393"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="558" mass="61397" checksum="028FDC6513C21B9E" modified="2017-08-30" version="1">MKRLCKFLLSGLLCLFVSGAGHALEKVDFIVSGRDKGSVSALESNGVTYVDVQKTARKFGTGIELFAQSKQAKISTKGFYAILTAPLAEIIINAQPHTLSAPVLIQGSKMMVPAEFFLLPQFQEAVDKYVSFQDGAFYVERRFNLEFSGEQKNKTDTLLVFDARKKIAYETKQLNKHTVTVTFPNVTLKRDLHSRTRTDFIASMDVRQGRNGEAVLKVILGKNAKDWSFTETDGKLVFRAGAQKAAPVLAAAPAAQKAEAPTSQPDAKPALKGPSLANEKPSVLMEDDGFIEMKAAPAVQPVMKAEKPAASKPAPVIKAEPNPLAIRTAHKKMRIMVDPGHGGKDPGAVRGRYREKDWNLDVAKELARLLKKGGFEVQMTRDNDTFIALSERSKKANQFKADLFVSIHTNASKNRSANGFQVYFRSEKATDKEAAEVAALENEAMQYEEVHYNFVDALLQSMAKNEYINESSKLAGYVRNAVYKQPGIGIAVNQNNSVRQANFYVLKGVNSPAILVEMGYISSSKDRGRLANGTVRDRTAKGIYTGIVNYAKKEGWID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB58</accession>
    <name>A0A1Y4DB58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fusA</name>
        <name evidence="8" type="ORF">B5F75_07215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56055">
        <property type="protein sequence ID" value="OUO56055"/>
        <property type="gene ID" value="B5F75_07215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="10"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="83"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="137"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="700" mass="77071" checksum="62C55E54F7D67371" modified="2017-08-30" version="1">MAEFKTYPLEKIRNIGIIAHIDAGKTTTSERILYYTGKVHKIGETHDGASVTDWMEQERERGITITSAAIYCVWKDCQLNIIDTPGHVDFTAEVERSLRVLDGAVCCFDGVQGVEPQSETVWRQADKYHVPRIAYINKMDRIGADFIRSANSIKEKLGGNACPIQLPIGAEDKFVGVVDLVKMKGIIWDGDHNGATFNEVDIPADLVEAAQKARTEMIEKLADFDETIMERYLNGETDFTVEEIKKAIRKGTLTGKFFPVICGSSYKNKGVQPLLDCVNDYLPSPVDVPPVKGTDPNTGDTIYRKASNSEPFCGLIFKVQTDPFVGKLSFFRIYSGTLKAGDAVFFPGKNATERIGRMMRMMADKREEVKELGAGEIAATVAIKNSRVGQTICAPEAPIVLESITFPEPVISIAVEPKSKADEEKMSNALARLAEEDQTFRVRTDEETGQTVISGMGELHLDIIVDRMKREFNVQANVGAPQVAYRETITKTVEQETKFVRQSGGRGQYGHVFLRLEPLEKGKGFEFVNEITQGRIPKEYIPAIEKGCREALDSGAIAGYPLVDIRVAVFDGSFHEVDSSEMAFKIAASMALKDGAKKANPIILEPIMKVEVVAPESNLGDIIGDLSSRRGQIGEMGVRGNVRYVRAEVPLAEMFGYATNVRSLSQGRASFTMEPSHYAEVPANVAKAIIEKRTAAKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBE8</accession>
    <name>A0A1Y4DBE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56473">
        <property type="protein sequence ID" value="OUO56473"/>
        <property type="gene ID" value="B5F75_04575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="312" mass="35964" checksum="13929E55A9DF105C" modified="2017-08-30" version="1">MRIFLFLISVLLLYPTALCAQRLPGGVLKAAMGKTVSQKMLKPLSNASIEALVARGNSQLVIQRALGVAWQRQDPVVNVLQDGAVHNELLRQWWKKASVYKYRWEEGNMLGLNSWLIVLAHRIREGIKLSPPTLRILEEQIALAQEEAEKEFKKQYKYIAMPPNYQDTPAFLKLLGESVAYRLDTNFLPTLVAADRVRLLQVLMHGMFSGPVDWRELHTAVLFREIRDCLHVCARQMKQIEFYGPMKAAMRDIARKTAQEAAENSIISLVKLREMFIEDLQEYAPHFEKDEQMKNDWALLVKFFQDKQNARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBG0</accession>
    <name>A0A1Y4DBG0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56483">
        <property type="protein sequence ID" value="OUO56483"/>
        <property type="gene ID" value="B5F75_04625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011009261" evidence="1">
        <location>
            <begin position="20"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="323" mass="35296" checksum="39ABC56095A19D4D" modified="2017-08-30" version="1">MKKFYLALACLLMASWGMAQEEEIMIINPGRETFVHFPSAVLGNQHTLTVFLPEKAVPLSKRYPVVYVLGAGPKNAQEAQDFVEKNHVLAVGIDFTEEDYQNREQIIEFISRELIPYIDTNYLTFADSSHRGIAAQGKNAALTALALLAKPHLFGAVALASGADAIEQFQLPLSGAPRIFVTGRQSELALAQQKLEQAGLEYGKNFALAYVSSAAGLFEGVDWNYLSAPQQDVTLRRLKAEVDCPVLTLDSDEKSILTVTARLNNGATFAYVPDSLRISPPYLNWNPLKGELTPVAGAEPGKVKISGGVDKKAFSVKIKLKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP9</accession>
    <name>A0A1Y4DBP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56583">
        <property type="protein sequence ID" value="OUO56583"/>
        <property type="gene ID" value="B5F75_05160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010181">
        <property type="entry name" value="CGCAxxGCC_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09719">
        <property type="entry name" value="C_GCAxxG_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01909">
        <property type="entry name" value="C_GCAxxG_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="16737" checksum="BBD98B159E79096E" modified="2017-08-30" version="1">MNEPAVKGEEAKRLFLNGYNCAQAVFLAFSKELGLDDKTALKLSSGFGGGMGRLREVCGAVSAMFMVLGLKYGSDNPSDHAAKAQLYARVQELARRFKEENGSIICRELLSLPPGPQDPTPQPRTQAYYKLRPCPDKVASAAAILEQYLRENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT2</accession>
    <name>A0A1Y4DBT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_06790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56315">
        <property type="protein sequence ID" value="OUO56315"/>
        <property type="gene ID" value="B5F75_06790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="18848" checksum="8CCA7FE1618D6E7C" modified="2017-08-30" version="1">MIYWKLFVTFFKIGLFNFGGGYAMISFMQNEVVFKHAWLTTAEFTDVVAISQVTPGPVGINLATYTGYTAADGVWGACVATLAVCLPSFILMLAVSKFFLKYRKAASVEAVFSGLRPAVIGLIAAAALVLCNRENFVDVKSLLFFAAAFVAVWKYKLGPISVIAVCGLAGWIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT8</accession>
    <name>A0A1Y4DBT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56042">
        <property type="protein sequence ID" value="OUO56042"/>
        <property type="gene ID" value="B5F75_07120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013368372" evidence="1">
        <location>
            <begin position="30"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="445" mass="48476" checksum="A4D3320A4720C9E6" modified="2017-08-30" version="1">MLYIYYMKNNIFRLSLLAVFLCFSALAGAQITVVRVDGSSIYLDTSSAAKAPYKGQSFKVIVSTEKLTNPQTGKDLGDIYHYSPVGKITEVQPLYAVGEMANPAGIAVGQQALLEESADPAPAAAPQPQALQIPGEVRKKIIYAPIAQEIISVTEADVSAPGAQNLVTLSSDRQVTVWSRGENNTLKEVFSYFLPSSAQPITISAVPVKKGNAQIFVTVYTPARKKVSAFVLENKNGSLEKTAELPFFVKEQGCGAEKTVWAQTPFVSEEYPGNARQVVYEDGKFKASKKSFATLRNWLTGVARYGVEKEGADNLIYTSSTGTLRMVLQNGKRTESKDLFASSPNRVKYKQEILEFYPSVQVFGPQGDATIAAVENDAKIGLLAQMFGQYQNGKIHFLTYENGQLTVQDTTPLDGVVYDTACSQRAVLAAEVLPNGNSRIVEIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT9</accession>
    <name>A0A1Y4DBT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56536">
        <property type="protein sequence ID" value="OUO56536"/>
        <property type="gene ID" value="B5F75_04910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013391277" description="M20_dimer domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="214"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="490" mass="53209" checksum="8E2E219929E8EB9B" modified="2017-08-30" version="1">MIKRILAIGLACWALSFSAQAQENDGWAALNAEAKRHLINLLNIDTSLPEPDELSAARYIYKEFNKHGIDWDIFIPSQGRANLMARIKGSDPSQKPLLLISHLDTAPAAEGWIYPPFKATAENGNIYGLGATDAKNYTAVYLALFTWLKDQKITPARDLIFLATSGEESGSETGLLWLGGAHWDKINPGYALNEGGGIIKNRGGADIVFAEASTKMYMDIKVTAYGTGVHSSMPVNDNAVYLLSQALAKIAAYNPPARLTPTARTFFKAIAPLQDEDGQTTIDFLLNGTPQNSQSAAEVMALDPFFRTQLKDTLNPTVLSASKDTGSASGEASAILNVRLLPGSDPDEFFDRLKNLFTEEDNITLEMLERPQTPFPTPMDGTDELFASISKTAQKLFPGAITVPGMSPASGDSEFLRKLGVITYGLGPDMDPLAENSAHAPDEFISEKDLYNQLQFIAGIVFDFAYGKDLLPLTPQQQTPAPPTENTPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBU7</accession>
    <name>A0A1Y4DBU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">B5F75_06840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56325">
        <property type="protein sequence ID" value="OUO56325"/>
        <property type="gene ID" value="B5F75_06840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12611" checksum="43CC9077FF96EE26" modified="2017-08-30" version="1">MIKNTGYRKLGKTASHRKAMLNNMATSIILHEEVKTTLPKAKEVRRVVEGLITLAKAKNERAAKDTLKDAAAMKKLFEVLAARYANRAGGFCRIYRAGVRQGDNAQVAIVKLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBZ8</accession>
    <name>A0A1Y4DBZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56653">
        <property type="protein sequence ID" value="OUO56653"/>
        <property type="gene ID" value="B5F75_05535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="195" mass="21027" checksum="B9744E8F64D079EE" modified="2017-08-30" version="1">MAGEYILDLETVKEITKAKDDAQAAAQIGAVQELMEAYLNVTFIKRDIADEAVTLPYKKISIISPQYAPINSVKEIKVLQSDGSYQAAADIKYSIGKETVQILAGSLFVPGVMPRPAGQIAALKISYNAGLYDDYTQAPALLKSAAQGLLGWLYADPYAMGGYSSEHLSDYSYTKAALVRGLPEGIASILDKVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC08</accession>
    <name>A0A1Y4DC08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56663">
        <property type="protein sequence ID" value="OUO56663"/>
        <property type="gene ID" value="B5F75_05585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="141" mass="15999" checksum="9A8C9395A18567EB" modified="2017-08-30" version="1">MLLLGGANMKLKFRDWLIRKAFGTRFVEAKMENENTPKEERIICLQIGSHLRNCPLMKNSGHCILDCGCDQLEGIKCNKGLPRTEAIERMAKALYDKYEVRCNSDDCPNEGPICEGCPIWEKYEKMAEAALDALLEVSINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC28</accession>
    <name>A0A1Y4DC28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56683">
        <property type="protein sequence ID" value="OUO56683"/>
        <property type="gene ID" value="B5F75_05220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="13"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="329"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="362"/>
            <end position="369"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="574" mass="64256" checksum="3ACE42CF02A23945" modified="2017-08-30" version="1">MWPYVKPYWGRAVLGVLLTIPVGALDGVVAMFLKPFMDKVMVDKQPHFSAMIPFLIVGFTIVQGTLIYASNYLNTWVANKITIGVKRKLYDKLLSMDTSYFDRNNSGTILMRYSNDAETASNGLIDNLKQFLSKSFSSISLVFVLIYNSWQLAIIAIAVLIFFLYPMSVVRKKMKEIMTKTVGNLSYVMTIYNETFAGNKTIRSFTLEDEFRGRFRDLTDMRFSLAMKLIKGTNWLSPLMHVIMSIGIALVIGFGSYLIVSGAITSGNFVAFIAALMMLYTPLKSVGNNYISMQQSFLAIDRIFNILDLQPKIKDHAEPKELKTVSKNITFEHVYFEYVPGREVLHDINLEIPVGHTLALVGNSGGGKTTISALLPRLYDIKKGAIKIDGSDIRDISQKSLRKNIAMVFQDNFLFSGTVRENILLGNGQASEETIWQALKSSCLDDFVKGLPQKLDTQIGERGILLSGGQKQRLAIARAFVKNAPIVILDEATSALDNKSERVVQEALDNLMKNRTVIVIAHRLSTIQNADKIVVINDGKIAEEGTHEELLKLHGAYYALYSMQFKKQEAQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC43</accession>
    <name>A0A1Y4DC43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide chain release factor 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56626">
        <property type="protein sequence ID" value="OUO56626"/>
        <property type="gene ID" value="B5F75_05390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="6">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="352" mass="39953" checksum="1B710EB257A1A9A0" modified="2017-08-30" version="1">MDTTKYVTEFKQLEEELASGQLSSQELAEKAKRHAFLKPIIEKEQEINAAEKAIADDRAMIEAGEDKELVKMAADELAELEAKLPQLQKELRILVIPPDPNDSKNIYLEIRPGAGGDEAALFAAELLRVYQHFAQTKGWTTEILEYTPTGLKGCKYVSMFIKGEGAYSWLRNEAGTHRVQRVPDTETAGRVHTSTVTVAIMPEAEEIDIEIRPEDLEMETCRSGGAGGQNVNKVETAVRIIHKPTGIVVSCREERHQGKNREKAMAMLRAKLYQIEEEKRNKEIYDERKAQVGTGDRSEKIRTYNFPQSRVTDHRTDKSYHNLMEIMEGNIGPILEDLRAYRVEQKLKNLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC84</accession>
    <name>A0A1Y4DC84_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56676">
        <property type="protein sequence ID" value="OUO56676"/>
        <property type="gene ID" value="B5F75_05650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="157"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="334" mass="38288" checksum="BC1DF4D2D04202C5" modified="2017-08-30" version="1">MHIYTDKRTGIKYISYTDPSGKRVRRSLRTRNKSVATIKAADTIDNKKSADYSPLSVDAFLFKYREFLKATKSKQTSEIFETAWRKLTKLREIRALSEITPALLDDLQIAQKNAGVGHAGINRTTRALRTAMMQAEYWRLVTPQDWKRIVKFRENKNRVEFHTIDEIKQILAICPSADWELVVLLGCRAGLRRGEMDHLKWEDVDFVRGQLHIAANKTENFRFVPIDPVLKSALLSAQKKAKNEFVVNVGLSSSRGSKDYITTYYAHFTRKLPFHCHLHKLRHTFASHLVQAGADLYHVSKLLGHSSIKMTEIYAHLAPRALVDVVALLPKFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCB9</accession>
    <name>A0A1Y4DCB9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lpxD</name>
        <name evidence="5" type="ORF">B5F75_06335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56232">
        <property type="protein sequence ID" value="OUO56232"/>
        <property type="gene ID" value="B5F75_06335"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="358" mass="38600" checksum="AED581D93C4F00EC" modified="2017-08-30" version="1">MLNLPLSEVAKITGAEPGAKQDVTVRELCALEDAREGGICYLTSLEKTDLLKDLKASVLIVPQEAKGKELPFQGALLYAQNPEWAFILLMKYADAQKQKHTPGIHPTAVISPSAKLGADVCVGAYTVIEDGVTVGDGTVIFPQCYIGKNVTIGKNCYIYPQVVIREECVLKDYVILQAGAKIGSDGFGFTFHEGRHQKIPQIGNVVLGNDVEVQSNSCIDRAKISSTYIGDNTKIDNLVQVGHNVKVGMSTIMCAQVGVAGTTDIGNGVILAGQVGLAGHMKIGDRVQIGAQSGVISSIPAGQVYFGYPAMPQREAFKQQAMLRKLPELYKEFRAMKKQADEVQKLSFFGKLKKLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCJ1</accession>
    <name>A0A1Y4DCJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="3 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gcvT</name>
        <name evidence="10" type="ORF">B5F75_06770</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3 7"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56312">
        <property type="protein sequence ID" value="OUO56312"/>
        <property type="gene ID" value="B5F75_06770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="8">
        <location>
            <begin position="24"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="9">
        <location>
            <begin position="290"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="369" mass="40275" checksum="553D1575E96E94B1" modified="2017-08-30" version="1">MDVYFWRRPVNHTDLQKTPLCSACEKAGGKMVDFHGWLLPVQFEGIIAEHHAVRSQSGMFDVSHMGQIFVEGKDAWPFLQYINCNNIKNEPGAGVYSHILTEKGTIIDDAISFCLTPEKFLVVVNAACIAEDFAWFEKQAAKFNVTVRNESASWGMIALQGPQALEQAAKLLPQAKEVARFHIIEIELFGVKGYLTRTGYTGEDGVEIMLPGDKIENLWNALLQQGVKPCGLGARDVLRLEAGYLLNGADADQTRTPYEAGCGWVVKLAKENFVGKDALAAQKAQGVKEKLTGFVLKSPGVPRAGCKVFAGGQEKGVLTSGTFSPLFKGIAVGYLAAEAAVPGTEVEIEIHGRRAKAEVVKTPFYKNRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCR2</accession>
    <name>A0A1Y4DCR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ORF">B5F75_03375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56897">
        <property type="protein sequence ID" value="OUO56897"/>
        <property type="gene ID" value="B5F75_03375"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="144"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="266"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="399" mass="43156" checksum="14275CD61C72B850" modified="2017-08-30" version="1">MKNIVILGSTGSIGTSALDVIARLGPDYRVIALSANNNTDLFLKQLHSFKPRFAAVLNPASYEKIKDQMPEGTRLLPPEIDSLMFMASLPTADLIVSGVVGAVGFQPLVSAIKAGKTIALANKEPMVMAGKTLMKECERWEAAILPVDSEPSAIFQCLSGMADAHGYSKLEPQISRVFLTASGGPFAKRKGALSTVTPGEALNHPRWRMGKKITIDSATLMNKGFESIEIMNLFNLPEEKVQIVIHPQSIVHSAVEFNDGAILAQLGEPDMRVPIQYAITYPKRAPGPVKKLNLFETAKLEFFAPDLDRFPCLDLALAAARKGGLLPAVLSAADEVAVDAFLKEEIKFTDIAKLVYTVLKAAPQTQADATLNQALEADRWAREAAAACLKEKAYKKAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCR8</accession>
    <name>A0A1Y4DCR8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">QacE family quaternary ammonium compound efflux SMR transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56907">
        <property type="protein sequence ID" value="OUO56907"/>
        <property type="gene ID" value="B5F75_03425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="104" mass="11336" checksum="52C943CB33131448" modified="2017-08-30" version="1">MSWLWVLAAAFAEVCGTIGLKKFSSFPTWRNLLLFTGGFLFSFALLYTSFQYLAVSAAYAVWIGLGTTGAVLVNMFFFHEGRNAGRLAGMLLIVIGAAGIKWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS0</accession>
    <name>A0A1Y4DCS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56964">
        <property type="protein sequence ID" value="OUO56964"/>
        <property type="gene ID" value="B5F75_03715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="516" mass="59511" checksum="5E9C949B0ADF5CBD" modified="2017-08-30" version="1">MSISKIYSFLTRNKVLRFILTGCIFVAIVAAVICRFSLFSMSFEYDELFTAVTSDPVLSLGWIWSNWLVPDVHPPLHNVLLWVYNHWMPYGPEFWLRLPSVILGVGALACGWWLFPRRFGKTARLIFVSLLACHQYMILYSQHARAYALMLFLSVLLTFWFLDISRRIWHGKRIAASLWAKYALAALFLSWSHYFGTLLVGIFYILLFLQAWRYKQKLKPFIVLPVITGLLFLPWIIPNFLAQLQIHRFEENNWWANQDASWYMVKSSLRFFVFSRTGIAAFAVLVAGGAVGQILQRVRGRLCPFARERLLLLTAVLAVAAVTSLISFKMFLFIGRYFTPILPALFLWVALITARVVRKNNLFRAVLLVLLVAEVWTFTIQRKALLNPTMLPARLVSQFYYDFFRGREVMVLAVEAFPPRAMPAMYGYYIHKVYGVKADVTELVHLNPQERERVLARNKDAFVFMPNCEEGKLRKVADQWNKHLNIYGNLGSVCLLFITDQPETPPAGPKPIAAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS7</accession>
    <name>A0A1Y4DCS7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56974">
        <property type="protein sequence ID" value="OUO56974"/>
        <property type="gene ID" value="B5F75_03765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="190" mass="20195" checksum="8BDA72CA3E7B8D5F" modified="2017-08-30" version="1">MKKGFTLMEILAVLLVIAVVVSMAVPVFRSVRYEVKNGQAKAAAKKMAEAMRSYYQVSRGLGVKQECFTPSTTAGNAVVMAAPSACVSPTSDGIPYQNSTTNNSSRSSLSQLFACGYLSFKDFSGLPYEFCACNPISGGAQPTKCQITETVGTNTPLVVVRGASGAGKKYTSSSYHIFVNQTMKPQDNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCS8</accession>
    <name>A0A1Y4DCS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56917">
        <property type="protein sequence ID" value="OUO56917"/>
        <property type="gene ID" value="B5F75_03475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012101947" evidence="2">
        <location>
            <begin position="31"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="283" mass="30562" checksum="AAC49861DB1B88B0" modified="2017-08-30" version="1">MYYDKITELIMKKTFASFFVFFTAALPAFAASTCETRVDSHPDATTKQRVAYCLTPEPEPPLPAGPELVYYGVADTAPEPETQEPAKDREPVYFDKDGVAVNQHFVDTKKFPAFENEMLSEQERAALERLAKQDAAQAAMLRKPQGKTPAAAPQASVAKKPLEAPSVLSEENEAGLLARHQKPRRFMKTPAQETQPVSSYDENLYGVNAAQPAAYPGAQPQTPAVPTGTPQGELQQAYALENDPLSQPSGNAGGAAPNGFLDNNLVAGEQSFGYNATDPAMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCW5</accession>
    <name>A0A1Y4DCW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56963">
        <property type="protein sequence ID" value="OUO56963"/>
        <property type="gene ID" value="B5F75_03710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="58" mass="6307" checksum="C2EC992DAB9D5FF0" modified="2017-08-30" version="1">MNKVYQKSFFGIKNGGFTLIELLVVVLIIGILAAVAVPQYKLAAAKARFTQLQVAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCX8</accession>
    <name>A0A1Y4DCX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56973">
        <property type="protein sequence ID" value="OUO56973"/>
        <property type="gene ID" value="B5F75_03760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="165" mass="17765" checksum="B47EEB6A41825049" modified="2017-08-30" version="1">MKKILSKKTGVTVLEGLIALGLLALVAAGTFGVLLSVSRKAGTPDIRESMILAVERANEQLQMYPPVLYLSSDAEIPSELRNGLCGGDNNPLAIGRTHFINCMLPPICDRNTSSFYYTTGTEKVNMSVPFSANYNANGMVEGWGASPYASVISVKYYITCNGFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCZ8</accession>
    <name>A0A1Y4DCZ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_03370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56896">
        <property type="protein sequence ID" value="OUO56896"/>
        <property type="gene ID" value="B5F75_03370"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="272" mass="29747" checksum="F51160D204B3C186" modified="2017-08-30" version="1">MLLPRILTALIGIPVVLAAIHFGGVIYMAFVGAVILLCLYEYGLVLTAGKKPVHMPSLLLFGLLMAVVAILGRAPADMVDLPDNLYPFSVSVVIFGVLFFEVLTPKRSWDRVCNTFTGVFLIPWSLAHLVNLRDIATYGEYLTLFMIITVWVCDTGAYFSGRFLGRHKLNKEVSPKKTWEGAVGGTVLAVGAAVLMRHLFLSTLFSVSEAVWLGLLVAVVGQVSDLAESVIKRSTGVKDSSNLLPGHGGFLDRFDSYLLLAPLFYYVVLYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD33</accession>
    <name>A0A1Y4DD33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04890</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56532">
        <property type="protein sequence ID" value="OUO56532"/>
        <property type="gene ID" value="B5F75_04890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010162">
        <property type="entry name" value="PepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF2">
        <property type="entry name" value="PTHR42994:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01883">
        <property type="entry name" value="PepT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="6">
        <location>
            <begin position="184"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="383" mass="41653" checksum="5945F1AAE2D09C95" modified="2017-08-30" version="1">MMKLNQQRLIDTFLELVQIDSESFHEKKIHGFLVSRLKELGCRVYVDKAGSAYNTDAPGNIIAFLPGTAKSKPVVLCSHMDTVVPGKGVKPVVKKDCITSDGTTILGADDKAGLAIILEVLRTLKEQTQVPYPPVEAVFTLTEETGMQGAKNLDYKKIKGREGLILDNEEVTELLVQGPAVNTIEVWIKGLASHAGVCPEKGISALEVAAYALSQMKLGRVDKETVANFGVVQGGKVTNVVMDEVYLKGEARSLSDAKLAKQTAHMKACFEKAVKHFTKKIDGKVHKPQVKFVPFKRYPAVNVPRNNEMVKDILSAAKKLGVRVRAAASGGGCDANVLSGFGFTLPNLGVGCRNCHTLKEKLILKEFFQAFEITLAAVLAYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD34</accession>
    <name>A0A1Y4DD34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_02725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56775">
        <property type="protein sequence ID" value="OUO56775"/>
        <property type="gene ID" value="B5F75_02725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="110" mass="11407" checksum="7EDE8271D71098D5" modified="2017-08-30" version="1">MILLFFIGELPNMYTLVLILHFIVCVLLILLVLLQSGKGSAAGIFGASGADNLFASPTAFNAVNKFTAILAAVLMSTSIILTIASNKKSSESVLDSVKIPAPTAPAQAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD48</accession>
    <name>A0A1Y4DD48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57053">
        <property type="protein sequence ID" value="OUO57053"/>
        <property type="gene ID" value="B5F75_04185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="547" mass="59061" checksum="69BF563C6F94C25E" modified="2017-08-30" version="1">MFKLKLKPGNVFQKINKMDRKQAYTWGAIIVVCFVALLTLASFMGDADESSFDGFNTRGYDLAQMPFLNDEAEEYLLASKYPDMQGNNSTMLYSAAEKEARQEEDAAAAEEAAAEEDVSASGMDSADYVPGGYGGSGGGYSGGGASSGPTQIGQLDNASVSHASGSGVNTSWGAPRGDFSPYKSQEKGTEAPFQQLKNQDARRALSQFAQTSRAAAGLRDSKGANAKRALMGGHVQGSEAFTENGVDLSKSGGLALDTNAPVSSADLSNLDDALSDAAQQGKEEKDELTQDMADRLLEQLWSGMINLGMQTMGNLLGKGIDALGGVMSGHSAGRRYNNQVAEDILSKDWSELSADQKDVYLKLTGKTEADMANVKGPLRDDYANYKKGLAGSDTSASEKFTRPSERPSTESETVEIGKTKSSSKGNVDANQAELLEKERIAALKKQDKKWEDQIRKEFTSDLKANRDGSLADTFYNKGWHEVYDAEFTAHTGRTKIDTSNFSTGTTGGKQDIKFKSPSDFTTRTQYETYVNELPVETDVKEVLLKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD71</accession>
    <name>A0A1Y4DD71_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56976">
        <property type="protein sequence ID" value="OUO56976"/>
        <property type="gene ID" value="B5F75_03775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="171" mass="19008" checksum="9CD4B6FF8740D4B8" modified="2017-08-30" version="1">MKKQKGFTLLEVLIVVVIAVSVAAFAVPAYQKTQDRNRYLAAQGVLIDFGNGVRTLQAEVDFQFPWTTRNVTSSLQTTSLDEDAEITRSNASTALFARKYAAPIPFDLSNSYKGYYFSFCPENVASSGNCCQGNKDVVVCMYDSKYKSRPTKGQYYGAVYLKDGTIQRISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD80</accession>
    <name>A0A1Y4DD80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">KpsF/GutQ family sugar-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_03825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56986">
        <property type="protein sequence ID" value="OUO56986"/>
        <property type="gene ID" value="B5F75_03825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="40"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="209"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="277"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="333" mass="36300" checksum="B263C21C2E9B0A47" modified="2017-08-30" version="1">MAKLEYSPAEIKRIARHVLDVEHTALELSRKSIDDNFLKAVDVIAHTKGRVVVLGIGKSGIIGRKISATLASTGTPSFFVHPVEALHGDLGMITPGDVILAISFSGQTEEINKILPSLERRKLTVISMTGHDKSKLALMSDIHITVYIEREACPYNLAPTASTTATLAVGDALAICLMKIKHFEKRDFAVFHPGGSLGKLLTQQVKDLMRKGKNNPTVRESATVQDALFVMTQTGAVGATSVVDKKGRLLGYFTDGDLRRLLQKGTDVLHKNITEVMTKNPYHLTDTLPAIEAAKMIHATHVDNLPVLDKTGKVVGIIDEKDLIEFLALLDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB9</accession>
    <name>A0A1Y4DDB9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56865">
        <property type="protein sequence ID" value="OUO56865"/>
        <property type="gene ID" value="B5F75_03190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012689315" evidence="1">
        <location>
            <begin position="25"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="435" mass="47789" checksum="D57C82FB4660C345" modified="2017-08-30" version="1">MFYRKMRILLTLLCSAGCVCSAYAQGGKKLTTVVKAATQSSEKTLLKGASQNLGRLPAVSSAAAQAAGRQLTIRFPGDPVQLEIPFETESAPLDKALSQRVAQQVARQLPPPASLQEVHQLPSGETARLVRLEAKHFKKTHQLKATIRYLMKTTPKPVRLVSQKTGKQIIVVKNDRLRYFSDVEQACPAGSYLILHEDGKAEFLTPEQAPKNFAETYEKAYAQNNPSPFFDISFERAGASYKIQELKSLASLFDPSLGFGRVYDLPAHPINGQPVQVIVLSSPARVEGIGLLRYDSMAVRYADGSFDVHPADWVPPVLQDKIASLTPKRATPISISLSGELSMEPAPKRFYDGQADLARDLHQAFKGQGKPYTSLLMGDFIVYEIPAGIVYHPAGRAEELLNPQKKVIIYFPSSNSGQIIDRSLLDKPVFATPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDD5</accession>
    <name>A0A1Y4DDD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">B5F75_04150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57046">
        <property type="protein sequence ID" value="OUO57046"/>
        <property type="gene ID" value="B5F75_04150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="14"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="255" mass="28731" checksum="B34FD9BE0F6E58F9" modified="2017-08-30" version="1">MQKYGQHFLISENVIRQIVDAALLLKAAQLVEIGPGKGALTQRLIERGEQNFTAVEIDPKMVQYLRQTLPPQAKVQLKEADFLKTDLASLVTRPALFVSNLPYIDAADILDKVLSFPLFHAAVFMFQKEQAQRIRARAQEEGYGPLSVFSQLRARISPICKVGRGCFNPPPKVESMVLAFEKKSPWLVPLGDWQRFKKMVQAAFLHRRKTLANAWSLGGYEPQKIQHALQALSLAPSVRPEQVPPETYARLFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDF3</accession>
    <name>A0A1Y4DDF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flp pilus assembly protein CpaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57066">
        <property type="protein sequence ID" value="OUO57066"/>
        <property type="gene ID" value="B5F75_04255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017592">
        <property type="entry name" value="Pilus_assmbl_Flp-typ_CpaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031571">
        <property type="entry name" value="RcpC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16976">
        <property type="entry name" value="RcpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03177">
        <property type="entry name" value="pilus_cpaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RcpC" evidence="1">
        <location>
            <begin position="111"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="250" mass="27165" checksum="3B85637763EE2357" modified="2017-08-30" version="1">MKKGIFLPLVVAILAAIVYAMIVSSAEKKLNASKNIKQVFVPVRDIKEREVIKRDFIKTVPVPAAYLQKDAFTYTTDADFKAIENTVARIQIPKGNQISKYAITSLSPEAGLSSKIPVQMRGFIINVPIATATMIKPDDNIDVLLTFEAVMKSGTRQKVTVTLLQNVKVLGVGSDLGQGLDAKAANAMKNKEEDAAAYSDSSALSLALSPRDAQYLALAQAEGDISVILRSHGDVTNYLMEIATFEKLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDL0</accession>
    <name>A0A1Y4DDL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">B5F75_00020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57203">
        <property type="protein sequence ID" value="OUO57203"/>
        <property type="gene ID" value="B5F75_00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="27"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="339" mass="36913" checksum="A60FC75C72286EAB" modified="2017-08-30" version="1">MKKDFMILGIESTCDETSAALLKGGKEIVTNVIYSQIDEHKKYHGVVPELASRAHAAKIATVIHEALGDNPIDCVAFASGPGLPGGLMVGRVAAETLANFKKVPILGINHLEGHIFACDFEGTEVKNRLEFPLVALVVSGGHTELWYVKGYGEYKVLGKTRDDAAGEAFDKVAKLLGLAYPGGPQISKQALSGRRDAIHFPRPLMPGTWEFSFSGIKTAVSYYLRDHQNFNIPDVCASFEEAMVETLVTKTLLAAKKYKVRHIAIGGGVAANTLLRERMQQQAAQAGITAHFVERKLSSDNAAMIALAAYKKLEHAEKTGKPVKKNIDINPNMKVRSWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDM0</accession>
    <name>A0A1Y4DDM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="14" type="ORF">B5F75_03720</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56965">
        <property type="protein sequence ID" value="OUO56965"/>
        <property type="gene ID" value="B5F75_03720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="13">
        <location>
            <begin position="16"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="12">
        <location>
            <begin position="598"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="788"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="682"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="725"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="364"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="844" mass="94137" checksum="C7FF53CD3DE8876D" modified="2017-08-30" version="1">MAEEIRRTTLSLPTVVPAVAIRDVVMFPGMSLPLSVDREKSIAAVELALNTPEKYILAVSQKNAEIEEPKESDIYHFGVIAQITQNLKMPDGSMKIFLQGLARARVTKLEMNDVAGSWFATVEYIEEEEDDSPVVQALMRKVLDEFDHYARVSHRIAVEGVSFLRQINDPSKLADTVASNMLVKASQRQEILEAVHIKDRLEKILKLITSEVEILGLEEKIHSKVRAQIEKNQKEYYLNEQMKAIQKELSQKDDFQKELDSLRAKVKKNGLPPHAKEAAEKEIERLSKMAPFSPEATVSRTYLDWLVNMPWNKTTEDVLDLKEAKRILDEDHFGLEKPKERILEYLAVSKLTNSLRGPVLCFAGAPGVGKTSLAKSIARAIGRKFVRMSLGGVRDESEIRGHRRTYIGSMPGRIIQGISKAKSSNPVFLLDEIDKMGSDWRGDPAAALLELLDPEQNKEFTDHFLDVPFDVSKVMFITTANSLANIPSTLRDRLEIIDFDGYTEYEKHDIVDKYLLPKQMKMHGLKEGQLEVTYDAVSLLMRDYVREAGVRNLEREIGSLCRKASKMIVDGAKKVTVTKENLHEFLGVPKYSNFATEENGVGIATGLAWTSVGGETLSIEATKLPGKGQLILTGMLGNVMKESVRAALTYARSRGYGEGIDFDKTDFHVHFPEGAVPKDGPSAGSVITTALTSLLTGLPVKKHLAMTGEVTITGRILPVGGIKEKFLAAYREGVKTILYPHTNEKDVSEVPERVRKEMTLIPVKHMDEVLPLALEGWKEFEAKLQKKAHAKKRGAQKHKKAAQTVKKAAAKKSARPAKKTAKKASKSRSARQTASARRKGARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDM6</accession>
    <name>A0A1Y4DDM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57224">
        <property type="protein sequence ID" value="OUO57224"/>
        <property type="gene ID" value="B5F75_00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="33400" checksum="A7E951276A963FB5" modified="2017-08-30" version="1">MKKVLITGASGFIGRQVTKQMIARGYTVYAPSLAPTLPAQEGLIQHELDFFKPGALSDYLKEHQFENLIHLAWYVGPKCHMHPGNVQWLCLSLEMLKTFIENGGKKFLGAGSVSEYDFSYGLLREDKTPLNNPSLYGQSKAALYKVGSSLCRQAGIDFKWARIFNLYGPYERAARLMPSVICSMLKGEDVKVSPCTKFLDYLHVEDTARGIAMLFDSPVTGAVNIASGQPVQLRVMVEEMARLTGFKGKILWGALEENFADPVLAGANERLTKEVGWKPNYTLTSGLEQTINWWKEHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDS0</accession>
    <name>A0A1Y4DDS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57015">
        <property type="protein sequence ID" value="OUO57015"/>
        <property type="gene ID" value="B5F75_03995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="62" mass="6708" checksum="A8BC5C2A7DD462E5" modified="2017-08-30" version="1">MEWIQNNWNDVLSLVGAVILIVTVVVKLTATDKDDTVWAQVLKVLSALSLCNPDGSLIGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDS4</accession>
    <name>A0A1Y4DDS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56792">
        <property type="protein sequence ID" value="OUO56792"/>
        <property type="gene ID" value="B5F75_02810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="21280" checksum="E3C5A9D4323F5ADA" modified="2017-08-30" version="1">MIKKRKIKSEKNPVFLFAKYDILLLRIIINNMNLQLNEQKEELQKRLNRFEAQCRAKGLRVTEQRREIFCTVAQSCEHPSAEKVFQSVRKTLPNVSLDTVYRTLASLEDMDLLMRVGLSSKARFDGDLRPHCHFVCTRCGEVYDIFPQTGDAPLPLPRAAREMGEVKQVNLQLRGICKKCQAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU3</accession>
    <name>A0A1Y4DDU3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclophil_like2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56812">
        <property type="protein sequence ID" value="OUO56812"/>
        <property type="gene ID" value="B5F75_02915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041183">
        <property type="entry name" value="Cyclophilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18050">
        <property type="entry name" value="Cyclophil_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012034175" description="Cyclophil_like2 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclophil_like2" evidence="2">
        <location>
            <begin position="41"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="148" mass="16542" checksum="80A616CC30B1BB1C" modified="2017-08-30" version="1">MRFLSSLSAVILLLSACLAWQAESNTLDAKPQNALTMNLLINQKSFPVILADNPTARAFAESTPLTVTMNDLNNNEKYHYLSRPLPAQPKTAGHIKAGDLMLFGNDCLVLFYKDFPSSYRYTRIGTVQNPQQWVQMLGNNTVTVTFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDV1</accession>
    <name>A0A1Y4DDV1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57216">
        <property type="protein sequence ID" value="OUO57216"/>
        <property type="gene ID" value="B5F75_00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="26423" checksum="FB3FDDBEE7A35931" modified="2017-08-30" version="1">MPALRAAVEQVSKKMGRTQALKRVDASFAAGQVHGIIGPNGAGKTTLMRLLAGLLHPDTGSVSYFQGDQLISAEAAKRVTGYFPQEPSLYPDLTCEEHLEFFRDLYDLPQADFIRRSEELLQATGMTPFKDRPAGKLSGGMYKKLGLMCVLLNRPQLLLLDEPTVGVDPVSRQELWDLVYGFAGENMTVILSTSYMDEADRCACVHVLSGGEMLASGAPQEVTAQFGVHDFAEIFLNHEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDV3</accession>
    <name>A0A1Y4DDV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56822">
        <property type="protein sequence ID" value="OUO56822"/>
        <property type="gene ID" value="B5F75_02970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012599058" evidence="2">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="250" mass="27740" checksum="4F4AD7EB365A7E48" modified="2017-08-30" version="1">MKLSINNPLWAVVCAAFVLAACSDQPEPKETAPAQPQAQEVQPVQPAPKPAPAPAAKPKPAPLPDLTAQQLADKLKQWDEKLALLQTDFIQNTSYDGVEVSRSQGKLFYDRAQNRLRLDTLSPDGFLEQTAVTDKKDIVILDENNQHVTTLSWADWQQGQPNQALFDFGNYTALLEKHSAAVQKQDGQTAVLVLTPKEGEEYTLYLTLSKRDFFPQVITIQSELMVTRADLKNTQKNKPLPADVFGGFNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDV7</accession>
    <name>A0A1Y4DDV7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57304">
        <property type="protein sequence ID" value="OUO57304"/>
        <property type="gene ID" value="B5F75_00555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="26142" checksum="DDA82CE7B6C0A77A" modified="2017-08-30" version="1">MMDKKNWILAGAFVLVFLAGWFLARMGGSSVAPVLAQNTETPAGSDSLLVVDMQDADEPEGVVAVLEPKYVDDSQIPSQLSKIKVQGIERVVSRTGDSIDAPSQDDSAVMLGDVERTRIQSSVAPVSPKNEDDSKISMIEAPVQAKVIKNLEEYKKFKRTARGKYPEANFAKDYVVVLESTSNLPDKVFEIQDVQENDGKMLVIYRVNIFGLDQKTNTHSAVRIDKTDLPIELKQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE12</accession>
    <name>A0A1Y4DE12_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57337">
        <property type="protein sequence ID" value="OUO57337"/>
        <property type="gene ID" value="B5F75_00755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="371" mass="39917" checksum="2A8CF9D457EAACB6" modified="2017-08-30" version="1">MKKFLILLFCVFSAACSSMIPYKDQNLDYLQGIEKDPSAYRGQVVSFGGEVKGTTEDTLRLRLVLKIDAPLYYYATGKGNALSYELLLVTFNKRSMPAMTGIKKGHEIKVLARVSSYETRKNFTGKDIAVLHLLAFAISDRTMHKDFFRPETPDRQLYESWKEGRLFFEESAQEVIARYPVPAGQDMPVPVYVPPAQEPAPEPAPAASEPEKGIVFDAEEPTFIVAPQEPQAQHQSTQTASAPENAPDGKQASSSDKTLPPAAEKGEEPTDKLPSATEPTTQEAAEEAALPSDSSAPAPVQAAPANEPGETSQDLAPQQAPMPPAEQPLATPAPQPQTDAQAAADSQPQTDALPQDITAPAEVLPSSSGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE19</accession>
    <name>A0A1Y4DE19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57363">
        <property type="protein sequence ID" value="OUO57363"/>
        <property type="gene ID" value="B5F75_00905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013209361" evidence="1">
        <location>
            <begin position="21"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="383" mass="43579" checksum="9220611A1D614CBB" modified="2017-08-30" version="1">MRTFLLCCLLLGAFPLSSWAQLQKLPSVVAKELLGSSASAAGGRIAGVSPSAAAVLSQRKNYIKNLEENGFEDLNTMLEDYFTLNPQAATSKLLQQNKEMQRALVAHWLERDAYAYSRKGELQKNVQVEPVQGKIDYLNYIPYDARLVLLGEVHEINWMAQNVEEALMQFKRAHPDKNIYYASEFVDAPPVPELYILKKEKEVDQLVVKRPYYRPLTKRLLAAGVWVVGLENPALSRELLRTRYTSFQQTPLAWKTIAPSGMQERNQYWAQIIRRIYAQDPDAVVFIHAGMGHTDYNQPFSLPLLLKEFKPFVVEYSSSGIGDFNTLLERNIPIPISVRGLGRQLQQSNPSQPVFLIRWMKSKRSALVGGCDLHIQKVAQRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE31</accession>
    <name>A0A1Y4DE31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57357">
        <property type="protein sequence ID" value="OUO57357"/>
        <property type="gene ID" value="B5F75_00870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="320" mass="35518" checksum="F4D3684F7BE09060" modified="2017-08-30" version="1">MFNPLNAFALPDGPEAKQAFLVGGSCDEYRNNFTDEFNAWNNFLSSKKWQVHGFIDEAKKTEVADVKPFFWKDFLVALQQVRNEPVKQVLIVISTHGSNKKEIHGICDQSGHYHDIRDLNPILQQLQEHSVQTAVIDASCYSGFSVSAIGDNASCVMSMAGKNIGSGSISELVAKGLLTMPTLAQKASVEDVWFSVLNQSVKRLAHVPLITGMPDIVHWVPAPGALAQHFFSNRRAFPSESTVSRWEQMSVSAEELESGRQFFAKNTALFERLFSPQALAGISAYLQDGHFVAISSPAASVFYLQTHPKRKDRPCANFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE37</accession>
    <name>A0A1Y4DE37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57306">
        <property type="protein sequence ID" value="OUO57306"/>
        <property type="gene ID" value="B5F75_00570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="98"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="328" mass="37315" checksum="31DF5D5216EDCCC5" modified="2017-08-30" version="1">MKKILGCAAAVLLLAACSDGNERLFKQAQLATSKGNYTQAMQLYSRLLKQDPKNASALANRGILWERLPFENEKERAKNRAYAEQDYLKAIEANPNIPEIYNNLGALYIDMGRYVPAVYYLSDAISLNPKYFTALMNRAIAYFRMGRVTDSLADFNRAFRIRQDEPLLYLNRGLAYFASGQYELALDDYTYLISLTPDDARPYLERARAFIKAGYPAQAYADLEEAVSIKPTYALAYYYMGDLMFRRGETDYALGLLVKSKELASQYVPTYDLMGDMLSVEDPVAATANYMVAKKLDPANAAKYDRKIKLMRTEEGRQRVLAERFFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA6</accession>
    <name>A0A1Y4DEA6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57225">
        <property type="protein sequence ID" value="OUO57225"/>
        <property type="gene ID" value="B5F75_00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047343">
        <property type="term" value="F:glucose-1-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02524">
        <property type="entry name" value="G1P_cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013446">
        <property type="entry name" value="G1P_cyt_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47183:SF1">
        <property type="entry name" value="PTHR47183:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02623">
        <property type="entry name" value="G1P_cyt_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="259" mass="29436" checksum="29260369FEC30E6C" modified="2017-08-30" version="1">MKVLLLAGGLGTRLGEETSIRPKPMVEIGGYPIIWHIMKLYTHYGFTDFIILCGYKSEVIKEYFLNYYTNNSDVTIDFSNNQIDIHRNRCEPWKVTMLYTGRNALTGSRIKQARHYVGQEPFMLTYGDGVSDVNIKKLLEEHNRSGKLVTLTAVQPTGRFGAINIQADNSISRFQEKPVGDGAWVNGGFFVCQPEAFDYIADGENVTWEKEPLCSLAQAGQLGAYKHNGFWHPMDTLRDKMELNELWAAGKAPWKVWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB1</accession>
    <name>A0A1Y4DEB1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">B5F75_00185</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57235">
        <property type="protein sequence ID" value="OUO57235"/>
        <property type="gene ID" value="B5F75_00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="402"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="127"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="466" mass="48915" checksum="678BB89744B1D2B7" modified="2017-08-30" version="1">MPADLKTMYEGILAACGGADNIVTLGCCMTRLRFTVKDEALVSPEALRRVKDVAGYFYSGSQHQLIVGPSTANKLAAYFRERHAFAPLQLSGDYALSGVINAEIGDTKGNKAAVRKRYSSVLSHVCAVIGNIFMPLIPAYIGCGLLLGITNILSKTVLTGDSNLVALLSVFGNGIFFYLNAVVGYNANKEFGGTPALGVAFAGILNMPALAEVSLFGASLMPGKGGVIAVLLVCWAGSWLEKRLRAWFKGSTEMFLTPTLTIFIVGVVSLVLIQPAAGWLSEQLALQTQNALKHGGLITGALLGGSFLPLVMLGIHQSLVPIHQQLVDSLGANPLFPILCMAGAGQVGASLAVLWKTKNSKLKTIVKNALPVGLLGIGEPLIYGVTLPLFKPFIGACLGAAVGGAVVAVFHVTSAIPFGVSGVVLFLVLSNLRSVLFYALGFLAAMAAGFLFTWKLGFDDPPEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB3</accession>
    <name>A0A1Y4DEB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57396">
        <property type="protein sequence ID" value="OUO57396"/>
        <property type="gene ID" value="B5F75_01080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="3"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="187" mass="21156" checksum="88D48AF2969B0B9C" modified="2017-08-30" version="1">MKKIVLTGGPSGGKTTALSILKETFGNKIALVQEAATLIYSGGFPRKDNSPVHIEHAQNIIFYTVHQLEHLAEVTSNAKVMVCDRGSIDGAVYWPYGPENFFTSMHSSLEAELARYDAVIHLSPPPEKDFYQATNVRTESLQQAFEIDDKILKIWEKHPNRLVVPREKHYFEKAEIIKNFVEKLISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB4</accession>
    <name>A0A1Y4DEB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="15">PTS glucose transporter subunit IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">B5F75_01600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57493">
        <property type="protein sequence ID" value="OUO57493"/>
        <property type="gene ID" value="B5F75_01600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00212">
        <property type="entry name" value="PTS_IIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036878">
        <property type="entry name" value="Glu_permease_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018113">
        <property type="entry name" value="PTrfase_EIIB_Cys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013013">
        <property type="entry name" value="PTS_EIIC_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001996">
        <property type="entry name" value="PTS_IIB_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00367">
        <property type="entry name" value="PTS_EIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55604">
        <property type="entry name" value="SSF55604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00826">
        <property type="entry name" value="EIIB_glc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51098">
        <property type="entry name" value="PTS_EIIB_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01035">
        <property type="entry name" value="PTS_EIIB_TYPE_1_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51103">
        <property type="entry name" value="PTS_EIIC_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="323"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-1" evidence="14">
        <location>
            <begin position="7"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-1" evidence="13">
        <location>
            <begin position="481"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate; for EIIB activity" evidence="11">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="564" mass="61424" checksum="0E0146B76E09AF8D" modified="2017-08-30" version="1">MASSKNHKILTVIQTIGRSFFLPISILPVAGLLLGIGASFSNLSTVQQYGLESIMGAGTVLNHVFMLMSSVGNAVFANLPLLFALAVAMGMAKEEKAVAVLSAALSFIIMHVTIHELLVFSGQVLPDGKLASDVIAGTIGTTLGIQTLEMGIFGGILVGLAVACLHNRFYRIELPVVFSFFGGVRFVPIICTLAAIVLGVICFYVWPPIQRLILASGALVVKTGYYGTFIFGFMERALIPFGLHHVFYMPFWQSGLGGAMNIDGTMYYGAQNIFFAQLASHNTQHFAIEAARFMTGKYAIMMGGLMGAALAMYNTAKTNKRKLVGGLLFSAALTSFLTGITEPIEFTFLFVAPLLYVVHCVFAGLSFVLMHVFQITIGTTFSCGLIDYVLYGVMQGNDKTNWVRLLPIFVIYFVVYYYLFRWVILKWNLPTPGREADDQETKLYTKADYQAKQEKKEAAEQAAQTPAAAAPTEQSVGFERDEQMENIIAGLGGLDNMENPECCATRLRLNVKDSSKIDKALLKKAGALGVVINGNAIQVVYGPVVSVIKPKLQEYMDKKRAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DED8</accession>
    <name>A0A1Y4DED8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57426">
        <property type="protein sequence ID" value="OUO57426"/>
        <property type="gene ID" value="B5F75_01245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="453" mass="47821" checksum="81E0DD5F430FCB76" modified="2017-08-30" version="1">MEQTVMEMFTQAVVKFNAVLWGAPMLVLIVGISVYFTWKLKFIQKHLLQAISLSLKKSNAAGAVSSFGALVIALAAMVGTGNIVGVAAAVSTGGPGALFWMMLSAFFAMATKYAESVLAVKYREKNEAGEYVGGPMYVLKKGLQMKKTAAVFAIATALMGFADALIQTNSLVAIYDSVFKAPSFITTLILIGLTGAVILGGVRKIAAFCKWLVPVMAVVYIVSCVAVIITHVDKLPWAIACIFKSAFSGTAVLGGAIGITLKEAVRYGVARGVLSNEAGSGSGAIAAAAAQTPNPVRQGLISATTVFWDTLVICLLSGVAVVIAGDWSAGSLFGAQLAENAFSTLPGGSVLLLISLSLFAFSTLVGWSYYTAKSVQFCLGVNVEKPVYWLWLAVMCVGGFLSPKLVWELADTAIAVMCIPNILSLWLLRKEVFEETKTYLALELQAARSAAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE0</accession>
    <name>A0A1Y4DEE0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57002">
        <property type="protein sequence ID" value="OUO57002"/>
        <property type="gene ID" value="B5F75_03915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="63" mass="7703" checksum="1CBF3D06F73E7E28" modified="2017-08-30" version="1">MARKGFWLDYSKIRETGKRPMRRLKENPFRRYFIVANLFLAAQTPFWRKETIDILPPQAIKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG5</accession>
    <name>A0A1Y4DEG5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57553">
        <property type="protein sequence ID" value="OUO57553"/>
        <property type="gene ID" value="B5F75_01910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="371" mass="43089" checksum="C4C7AC7B14EC4553" modified="2017-08-30" version="1">MINTVGLLLQPHAEFELSSKACVDDIEANWKYLRKQKDYFPALELLPDERLKIEFSPSKVWCGQNLYEIVPSDIPQVLLRLNTLLNKAHVLTCPAILFYAHVYRIDYAKVCYLPFSSQTMWSCLQEQHRGGHYRQAFTFYTDDGHMAAGSLKRRKVCFYNKTAEILQDKRNEDELKDILNNLPGTFYRLECSLKTAKEIDRELKVCSVSVESCCLKDLSQENVVRAVLQKNLEKTVQHWHVPDKAKALDKVRMWLDQKEYENTRSLLTDMLHVMSCVYVGVEDVRQIIEKKLGKRRAREFIQRFEKLQLEDVHCLAVFKETFMKAVQELNPLSNTDLDELTRKEIVTESDTCLFAPVLLAIVELFISTPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI7</accession>
    <name>A0A1Y4DEI7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57476">
        <property type="protein sequence ID" value="OUO57476"/>
        <property type="gene ID" value="B5F75_01515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="66" mass="7577" checksum="9AF9F86F1DC939CB" modified="2017-08-30" version="1">MDAYNISLGPFDEAYLEESRSVLEQYFQRPLSLEEVESIINSFLELEEVVRKVQGAPQNEGFTSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ6</accession>
    <name>A0A1Y4DEJ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57574">
        <property type="protein sequence ID" value="OUO57574"/>
        <property type="gene ID" value="B5F75_02025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="188" mass="20801" checksum="D33D3137F80E39DD" modified="2017-08-30" version="1">MDKIYQTSLFKQKPGFTLIELLVVVLIIGILAAVALPQYQYAVAKAKYMEMLSLANDIRKGQQVYKMANGKYSADLFALDINFPPSFEAHPSYTSGGGTVYGVRNVGKRITCTMTTSVGSDVENWDPSGMLCWLEKDGIWYNITFSTGAQECRATRSSSFALDFCKRITGRKESAGGWGSAERFPFPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEP5</accession>
    <name>A0A1Y4DEP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PTS EIIA type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57567">
        <property type="protein sequence ID" value="OUO57567"/>
        <property type="gene ID" value="B5F75_01990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00006">
        <property type="entry name" value="PTS_IIA_man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036662">
        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033887">
        <property type="entry name" value="PTS_IIA_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
        <property type="entry name" value="EIIA-man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
        <property type="entry name" value="SSF53062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51096">
        <property type="entry name" value="PTS_EIIA_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="3">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="135" mass="14287" checksum="3CFBCA033560F3A8" modified="2017-08-30" version="1">MVKIILVTHGHLAQEMQETAAQIIGKPADESLAAFSVTAAASVEKEAAKLHDLLRTCEEGAVILTDIFGGSATNISLTASKDLPKCHVITGLNLSMLLTAINNRKKLSAKELAEKIEADGKRAVINATELLIKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER6</accession>
    <name>A0A1Y4DER6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit beta</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpD</name>
        <name evidence="12" type="ORF">B5F75_02495</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57663">
        <property type="protein sequence ID" value="OUO57663"/>
        <property type="gene ID" value="B5F75_02495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="143"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="151"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="472" mass="51197" checksum="1D2C9845F2638D8C" modified="2017-08-30" version="1">MKTGKVIQIIGAAVDVQFEQDHLPAIENAIEIEMDGGKKIVAEVAQQMGDGIVRCVSLESTDGLQRGAKAVDTEGPLSVPVGEGCLGRLMNVLGKPQDHKGDIKGAMQMPIHRDPPSLEDQNPTPEIFETGIKVIDLIAPYMKGGKVGLFGGAGVGKTVLIMELINNVAREHHGSSVFGGVGERSREGNDLMLEMSESKLADGSSVLDKTVLVYGQMNEPPGARAKVALTALTQAEYFRDVKGQDVLLFLDNIFRFVLANSEVSALLGRMPSAVGYQPTLNTEIGNLQERITSTKKGAITSIQAVYVPADDLTDPGVAATFTHLDSTSVLSRQIASLGIYPAVDPLDSTSRILDPRIIGEEHYNVAQRVRQVLQKYKDLQDIIAILGMDELSDEDKKTVARARRIQKFLSQPFSVAEQFTGHPGKYVKLADTIKAFKGIVDGEYDHIPESCFYMCGGIDDVLANYEKVKDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW3</accession>
    <name>A0A1Y4DEW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hrcA</name>
        <name evidence="7" type="ORF">B5F75_02245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57616">
        <property type="protein sequence ID" value="OUO57616"/>
        <property type="gene ID" value="B5F75_02245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="111"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="366" mass="41629" checksum="52B8FE3FC8C0EBCE" modified="2017-08-30" version="1">MRILKPEIAKARKEKILRWVIQQFVETRRPVGSQMIADGALPDVSSATIRNIMKELEEEGYLYQPHTSGGRIPTDKAYRYYVDYLANVQKMAARERQRIEEQYDARVNEVDNMLVQTSRLLAMLSGAAGFVYTANVDDQRIQRLDFVPVAPGLILVVLVTQAGAVRHWPVRTGYVIEPARLRVLSRFINEEIAGRTLAQARQVLWQHVHSGHREISDLADLTTQVLKDIERPQTSADELYVEGIGRLLANTTQDDYEDLKQMMRVVEERERFSSLLNEKMADMEKSNQKVNVSIGSENELAELRNLSIVSTACRVGDKTVGMLGIIGPKHMEYTRVMSLVNFIGSLLETSMNTWTALPSEDEKDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF08</accession>
    <name>A0A1Y4DF08_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57677">
        <property type="protein sequence ID" value="OUO57677"/>
        <property type="gene ID" value="B5F75_02570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825074" evidence="1">
        <location>
            <begin position="21"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="340" mass="37768" checksum="52923138882681B2" modified="2017-08-30" version="1">MYRKILLFILSIACGSGVSAQTWQKALEGAQKALSRPGAATVSSSRAALLNARMGMTLPASQGVGLWVDRRLSPLTPVLSNRLRAWAVLSNRLMLKDQPLREKQLQFFASHDQVPQGVLAAFPGTPLDFPHRLGEKTQYVLFGGKEGDLQMEALFKKFALQYRKAFADKKVIILSGTLPDRGVKFASELYADEKDRGFIRSFVREGFSVAGIGDAGPKPEGYLQQEKTNLIISAAEVPAAEAARSLHLYRSLAKWKEAFPQAVFLIYVSPMAAAYDWRYSLANSLPKEAVFSVSLTSVRNTKEFLFHRWNNFAYAKPGVLVWNDDVWARMSGFDAQMIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF21</accession>
    <name>A0A1Y4DF21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57676">
        <property type="protein sequence ID" value="OUO57676"/>
        <property type="gene ID" value="B5F75_02560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="410"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4131" evidence="8">
        <location>
            <begin position="11"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Competence" evidence="7">
        <location>
            <begin position="171"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="620" mass="68028" checksum="86DBAD24F344DC31" modified="2017-08-30" version="1">MHPDLYKRPLLWCLAALICLLLCFYRPAPAKRDVFHALPQKQVTLTGRVAHFPVHKKKSTNAVVKVLSVNGQLADGYVYARFAGFEPQWQDTLLLQGRLQKPYGIHLLGNFDWRHYLAQQHIFTESKVSQAQVVRPAGVFFRGLRALREDILHTFERSFAPELAAIAGGVLLGERGEISPRLYADFQDSGAVHLLVASGGNVGFVTLITVGLCALVGLGRKKTIICALAVAGLYTLAAGADAPLVRAYFMAVCACVGYLLGRNSGVFQGLLVSCFIILCLEPASVFETGFQMSFLATLAIIVCLSNYRLPAAWPGWVRFFAQIFLATLSTQLVLLPIFTNVFYKVSVTGLLSNMLLVPWASTLMGITFGYYVFTLLHMGFLLQGPAAWGLEGFKMLVEFFASFKLSSVPAAAWSPGAIAAYYAGLFWLFHLPQKQFARKLFWPCLIVAGMALGVQACFFSGGRVYLLNEWNKNAAIVKLSNGKVLLFEAGIAPEKLTSALYKIGVQKADAVLTFSHAPVPKELETLSKTGTVIRPFTPGVWPGDTLPAAGVPVRVTWGEHQTRQGKMWINAGYSGTRLDDVSYCFASREQDICLGAGARFVRIGENVHANQRNQTVKLQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFI6</accession>
    <name>A0A1Y4DFI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">B5F75_01110</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57402">
        <property type="protein sequence ID" value="OUO57402"/>
        <property type="gene ID" value="B5F75_01110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="3"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="345"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="39"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OUO57402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="456" mass="47756" checksum="AF98A9EBD3989CCE" modified="2017-08-30" version="1">MKNIVVIGGGPGGYPAALKAAALGAKVTLVEKGQLGGVCLNCGCIPSKSLLDAAHRFHTVKTISSLCAAGADEAAQALFALRDWPKIQARQKAATRKLTQGIAFLLKKAGVEVLQGVASFRDAHTVAVTLPDGSEKTLSCDGVILAAGSEAFFPPPFDQIKDQIYDNSTIFDIPALPETLAIVGGGVIGCEMADLMNSLGVEVSVIEMQPRILPLEDENAARVLAQALSKRGVHFYTGTSAAAVRREGERFTLTLSNGQTLSCAAVLAAIGRTVDLSALHMENIGVEWTRKGVQVNPQTLQLKDDIYAVGDVNGLFQLAHAASRQGEVAASNLCGVPAVYHNQAVPRAIYTTPEIASAGLTRAQAEAQGFSVKTHKAFLLANGRAVAQDQTEGYYELISDANTGRLLGGVLAGANATELVHTLSVALAAQMTVEQFKEVIFAHPTFAESLGEAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFN1</accession>
    <name>A0A1Y4DFN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57452">
        <property type="protein sequence ID" value="OUO57452"/>
        <property type="gene ID" value="B5F75_01380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="19863" checksum="859B0FCD6A5C66E0" modified="2017-08-30" version="1">MNCETLLEQISARCDKFRADLTAAAQNLRDFNRRLEQILQQLHKDIAVRDEDFAGQFNQYCLSLRQELDQDEPLWTQSRAQVRTYKDADWSGDLALAAKGLNSRAKTLSRACDEFTTAYDAFCKNYNGFTAAKLNVWLLTSYQNDAASLTGKILFLAREIAKKTERNRGPHVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFR1</accession>
    <name>A0A1Y4DFR1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choloylglycine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57492">
        <property type="protein sequence ID" value="OUO57492"/>
        <property type="gene ID" value="B5F75_01595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013277475" evidence="3">
        <location>
            <begin position="38"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="CBAH" evidence="4">
        <location>
            <begin position="38"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="378" mass="41259" checksum="A077C290F98B6C0B" modified="2017-08-30" version="1">MKVTFSFYNVLRRILMKKIFSCLLAAGLLAGQMPADACTGIAFKTTDGAQLQARTIEWGGFSLESQLVIMGRGQQNTSLTPQGQNGLSWKNKYGAVGISVVKAPFIGEGVNEKGLAAGIFYFSGYGSLAPFNPKRAKKSVADVELVRWMLTNFATVDEVIKGLKKIDIVTIYPPQEGQKTASTGHWRIADATGRSIVLEIENNGERHIYENTVGVLTNSPSFPWQVTHLKNYVHLQAGDVKPVSYGDTTLAAFGAGAGMWGLPGDITPPSRFVRAFFYLHTAPQAPTAQAGVLQAFHILNNFDIPIGVEFAAGEKIPDLPSATQWTSVTNMTRPAFYYRTMNNSQIRQIDLTKIDFASVSSQVLPLDKTPEQIEALSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG97</accession>
    <name>A0A1Y4DG97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57672">
        <property type="protein sequence ID" value="OUO57672"/>
        <property type="gene ID" value="B5F75_02540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169751" evidence="1">
        <location>
            <begin position="21"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="284" mass="31924" checksum="93EA82333663AACD" modified="2017-08-30" version="1">MRLKTAFISLILLICPCALCYGQLSFSGVNGERGYAALRARYRLDLDNGFVFTPMYGYYRMTDKEIDEAGSTSRYGLEVSYELNDAWRALAEGFWQPQAVGYQAVGYAAGLGWKPFYRWWIFKNPTLTGYAEQTRYRTYVDKQGNDLPSGAFGEVETGAHVEASADAGNWNVQAAWHKVIEYSSNPPHNLTFSWANIPFMTAVVQGFVKEAAAVRLSYRTELITPYASLARYRYNELSDTAAAVSAGLHVHLGEMSLSGGVEVFEPRREDNRKTYFSMSAEVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGC1</accession>
    <name>A0A1Y4DGC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LytR_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57702">
        <property type="protein sequence ID" value="OUO57702"/>
        <property type="gene ID" value="B5F75_00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_C" evidence="1">
        <location>
            <begin position="196"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="291" mass="32793" checksum="5F548F012F5B1B97" modified="2017-08-30" version="1">MEPSYKTRKIIERCLLVLLAGVLVWAGAAQFSSPLAQALIRHDASEIQLTVLTSPAMKFSYNPATQKAVVAVSSEKRSSKKHGSYTPEKGERFFIPQTEKREDFWNHFKHNLSSWRYNPLLAARTGWEYLTAWHDRRTNISPAEFLLLALELSKLDAADFAVRLPAASKSKRVRTPAPLPEIEDMAPLAVKDRPIVVEIFNASGKRGLALALTQYLREQNEKGLLRVDVLQYDNYPSYQEQSFIVDYSGRLVQVKQLSLAIGINSEIKSENAANAICDTRIVLGKDFEMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGI2</accession>
    <name>A0A1Y4DGI2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56038">
        <property type="protein sequence ID" value="OUO56038"/>
        <property type="gene ID" value="B5F75_07095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="10"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="263" mass="29698" checksum="837CBA719114E50F" modified="2017-08-30" version="1">METQKTPKQVIVMGDVHGQFDPFVKLLRHAGLVDDQLNWSGGHNRLVQMGDIFDRGPASRKVDDLLDRIQKQAAQTQGEVIRLVGNHELEPLLSNFVISGFSKEEAKLIHDKLTRQVLNGELKAAYAYKGILFTHAGVTRKLYKIFQMQLDDPNAANIAAMINLIFRESIKHEFYKHPIFNISISRKGADRFGGIFWEDLEDLASSYPKSPLVQVVGHTQVSRIILDKTANIIPVDVGMHRKLQYLIVDEEGAPHIIDVPEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGM3</accession>
    <name>A0A1Y4DGM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MotA_ExbB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56819">
        <property type="protein sequence ID" value="OUO56819"/>
        <property type="gene ID" value="B5F75_02955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="80"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="217" mass="23818" checksum="7ECBAED217F19D6C" modified="2017-08-30" version="1">MDFSNMTNVRELLAAGGPVLILLLLLSVYSISVILERFFKLRSSISLSRKLLAYCRHPIRSENYQKVEDACHKDIVKNTPAAALILRLVRERHRSDAELEKISDSIIDWEISKLQRRLTVLGTLGSITPFIGLFGTVIGVMHAFKDLASTTAAGAGASVVAAGIAEALINTAAGLFVAIPAVIAYNYFLSKTNYFAKELESAANEIIYRHNDESGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGV7</accession>
    <name>A0A1Y4DGV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusA</name>
        <name evidence="8" type="ORF">B5F75_03435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56909">
        <property type="protein sequence ID" value="OUO56909"/>
        <property type="gene ID" value="B5F75_03435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="138"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="461" mass="50911" checksum="29D32E543A5B3A53" modified="2017-08-30" version="1">MEGTAKDLVLALEGLEREKNIKREDILKTIEDALVSALRKNLGKTAQISAKIDVEKGTIQAFQTLNVVELVTNPEMEIDVEGAKKYLKNPKVGDVVTITLEVEDFSRIAAQIAKQVLIQKVRGIERDNFYKEFKPREGEVVTGSVRRFSDRDIIVDLGKIEAILPYCEQIKKERYVNGSRVKAVIAKVMNQNDLAAVGDDPVLSRYKSAAYKMDKGQRGPYVFLSRANGKFLEELFKVEVPEINEGIVEIKNIQRDPGFRAKVMVSSIDSKIDPIGTCVGMRGIRIRAVMNELSGERIDLINYSDDISTVIMNALAPAKADFVKIDSLAEKKATVIVPDDQLAIAIGKDWQNIKLASKLTGWNLEVKSESQKAQEGKEASDAVQAALADVEGIGPKMAEVLQKSGFTSVEQIAEMDVEHLSTVQGIGEKTAAKMIEGAKKYLADKQAANEQEDVNDNQENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH85</accession>
    <name>A0A1Y4DH85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57039">
        <property type="protein sequence ID" value="OUO57039"/>
        <property type="gene ID" value="B5F75_04115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012056764" evidence="1">
        <location>
            <begin position="19"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="464" mass="53071" checksum="45176CE787C03A61" modified="2017-08-30" version="1">MRKSYLFFMLCLTVPAYAQKNLLPAVRAGMARPAGVSQHLAKGISAVGVPGLNLPPDAAVFGGRNVPAAYERIKRLPGADKFLLREFIRKQLSKPFLTPYASVTNWRKHQAASYESSLQTPEEFQATLRQIDRMTLQDPDFKKFLFFRPEASLLSDYSAEAVLNNKLLVSHLQYLHQKFNWMKHYPNQGRDALHSVISSWGNVVRQLAGRLRQEKLIMLGEGHYQLEVQQAVGDLILELKKQNPNRRIVVFSEFAHLPVAGPQVVNQTAETYYRRVDESTSPQLSVEQAQQKRYARDVLLRLVRAQVEVYPLEDVVLIDLLKAANRQKAMLLQVASRNKIWARVMEYKMAQIRKTDPDALFIVYAGLGHVNRQRQYPLAAFFAPEKPVTVEFQFDPFVKKNILHFLWGEEVPLFARPLRASFSYWTGEDASLLARNSGFDYLVVVPHSLKGKLQRKYVSFINSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHC3</accession>
    <name>A0A1Y4DHC3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">T2SP_E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57079">
        <property type="protein sequence ID" value="OUO57079"/>
        <property type="gene ID" value="B5F75_04245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="206"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="594" mass="66293" checksum="74EFD7473B906340" modified="2017-08-30" version="1">MDRVSVICNAYDTPGSIPYEEVERFYSSLGREIDVFLPWDEDVMATSNRKEVEIITNPQSEWVKGLRLVLAKIRDLKAAPKDWVASVSDEEFTQAAKEIWSPILFDDGKTTSATEHIATADDEAGKTKLSFWDDLKQKIHKEVVHTLEIEHIVVSDESSASAQTRKRVAAIVDDILQKQPNLQFSRDQRTRFSSELLDEILGLGPLEVLMRDPAVTEIMVNAFDKIFIEQKGKLTLTKYKFRNNDQVVQVIKRIVAPLGRRIDESVPLVDARLKDGSRVNAIIAPLAVSGPTLTIRRFSQKPFGPEDYYRFGTISPECMAFIEKCVRIRKNIIVCGGTGTGKTTFLNAISGYIADDERIITVEDTAELRLQQPHWVSLESRPPNVEGKGAVTIQDLVKNCLRMRPDRIVVGECRGGEALDMLQAMNTGHEGSLTTIHANTPRDGLSRLEAMCMQTGVDLPVYVIREMISSAVNMIVQLSRFSDGSRKVTYITEMHGQKDGEIQSTDLFRYVQTGVDENGKVQGVFAPTGQLPTFFDDFAAKGQPVDKEIFLKNAIPLDENGEPDKLAVQRLQQAQQQAKSRQVPPAPPAAPAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHP1</accession>
    <name>A0A1Y4DHP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56448">
        <property type="protein sequence ID" value="OUO56448"/>
        <property type="gene ID" value="B5F75_04445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013051140" evidence="2">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="22390" checksum="5FBA771D832632F2" modified="2017-08-30" version="1">MKKVMIAVLLAALCAPAFAEGPRKCKGDDCPMPKGPRAEAVKAKQDKKDARAEEFKKARREHKAQMRATEEKMETLVQEYNKLKAGKKKDAKKEEIAKMVESIRKEQIKFKEEQLAKFQERLERMKKELDEEKSDKNIKAWVEEKTNAVIAEEGDLDVLFGGPAPRRMPGPKAGPRRGPGPEEMGPHAGGPALPPPPAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHX6</accession>
    <name>A0A1Y4DHX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56538">
        <property type="protein sequence ID" value="OUO56538"/>
        <property type="gene ID" value="B5F75_04920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="200" mass="20900" checksum="179220319DADD04A" modified="2017-08-30" version="1">MNNKKGFTLIELLVVVLIIGILAAMAMPAYFKAVERARAAEADTMIGTVVNAQQRYKMKTGKYAQNWTSLDVAPANATATAVYCTKGTQAANCGGQNAFEITLYGTSAADQNTSGVIAKRVGTGQYTYTLEKLYDSTDTPYCVPGTAPDDAAFCMEYHGVETAGDLPYTKNPQGTGQGASAWPSGYKKPAGTGAAAGGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI06</accession>
    <name>A0A1Y4DI06_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4HBT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56578">
        <property type="protein sequence ID" value="OUO56578"/>
        <property type="gene ID" value="B5F75_05130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="51"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="161" mass="18140" checksum="DBC0FB220A311866" modified="2017-08-30" version="1">MKKLRQPTSLQCFACGRNNPFGLKLEWYNDYDKRQVEASFSLDDNYCSYPGTVHGGILATILDETSGRAILLNNDFNRLMVTLKMEVVYKHNTPTHTPLKAIGRVIKDSGSRAMVEGEIVLPDGTVSAKCSSILYKIPQAVKDKWGPEEEEWKRTTPSVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI75</accession>
    <name>A0A1Y4DI75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sigA</name>
        <name evidence="10" type="ORF">B5F75_00940</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57369">
        <property type="protein sequence ID" value="OUO57369"/>
        <property type="gene ID" value="B5F75_00940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="360"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="529"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="530"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="336"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="415"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="504"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="360"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="570" mass="65704" checksum="46818346E7D6BA49" modified="2017-08-30" version="1">MASGNKALKDLVEEGKESGFLSLEDLNRSIAASDMSAEDIDGVMGTLDDLGIQVVDQKKFKSVSAPEKEALSEDWSSSPDISNSIRMYLSEMGKVPLLSRDEEITLARNIREREKELRKLVLESPITMREICNWEELVDQEEMTTKELMPRGKRTTRELNNMRKKLKDAAQFIGKREQEITKLMKELREGDLSDKKRNNAIEKLEAKQKEVVACITKLNLNQNKIKRLTNKIKNLADRLTEARNDMKRFDDYFGPYAEVKKLVNRFKAGKITEKEFKKATKFTLPELERALANIEDVQRRHAQMVETLPMTEKEFLAFNDRIVFFEDMILQDKLKLIKANLRLVVSIAKKHVNSNLELSDLIQEGGLGLMKAVEKFEYKRGFKFSTYATWWIRQSINRAIADQANTIRIPVHMKELVSKLTKVTNKFRQEHGREPTLEEYSKTLRLSVEKVKSVLKIMQDPISLSTPIGEDEDSNLEDFIEDKNGPNPTSAAVDFLRKQEVADVLATLSEREAKIISLRFGIDSGYPRTLEEVGKMFNVTRERVRQIEAKAIRKLRHPSRTKLLKDYQDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIA3</accession>
    <name>A0A1Y4DIA3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57389">
        <property type="protein sequence ID" value="OUO57389"/>
        <property type="gene ID" value="B5F75_01040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="598" mass="65429" checksum="0C6DF1E3915F3720" modified="2017-08-30" version="1">MKYWFFDGNDVVGPFEPKELAARRGFAATSLVCPENFSEDQDSWKMAVSFPDFHFDPSEVISIPAPEPAQETDSFDQEMDTLLKERSPLGDLEETPSVESPSLEIPKKPAKPGPIEDYFNNIKGEDLGNILGIPDPNENSDMNLARALQTQFEKTNPPTDKEVQPIEDDPFDEFTPKEEPEELPEETAPVSAPANEKAAAAEPLKKAEPAPAAEPTPASIPMSKTAEEDLVLTVHGQPPASKEQPLQQTPAKQETSTAKPEQETLQTTSQLPVLGQPETQLPPLPEQKISSFASSPQFNQTPEPAPAPDAEQKTISEVKSPQKEAPAKEDAQPEELVPASKQPEPVDVAPLQAEVPADTPPAEDPKEATVRHILEGKLDVTPTPEVLEPIKNVTVEPQVNHVRPRLKQTPEIQEFLNQTRNERIERERKNKKAMAALSVLIALLAVGAAAYINKTVMGASDPTPQAAAPQAQSVQPQEKSPADSSELLPDIPVPPPPQTITEPSQENKALSLVQNYRLPGNKGTIAAYLNQLYRPQLTQGYTASWSVEPLHKSTYIVKYRLTKTRMEPVVYIFQADVEAGKLTGALNNITLDLVGKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIJ7</accession>
    <name>A0A1Y4DIJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonucleoside triphosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56140">
        <property type="protein sequence ID" value="OUO56140"/>
        <property type="gene ID" value="B5F75_05835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01675">
        <property type="entry name" value="RNR_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02487">
        <property type="entry name" value="NrdD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="4">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="686" mass="78792" checksum="5E6EBF84F0CD96B7" modified="2017-08-30" version="1">MENSEVITHIVKRDGTTQRFDSKKITKAISKAAEATGEFDSETAKKLTIRAINIIQQLYSDTVPNVENVQDIVEDVLLTSNYHKTAKAYILYRDQHARMREISSKFNVDLVDQYLQKIDWQVNENSNMGYSLQGLNNYISSEISKVYWLNKIYPENVRRMHTEGDFHLHDLGLLGAYCVGWDLQDLLLSGFTGVVGKAESKPAKHLRTALGQVVNFFYTLQGESAGAQAFSNFDTLLAPFIYYDKLSYDEVKQALQEFLFNVNVPTRVGFQTPFTNLTLDLTVPSYYKDQPVIIGGKLQDKTYGEFQEEMDMLNRAFCEVMLAGDAKGRVFTFPIPTYNITKDFDWNNPKLTPLWEMTAKYGIPYFANFINSDMNPEDARSMCCRLRIDNRELRKRGGGLFGSAPLTGSIGVVTINLPRLGYLSKNEDEFFANLKDRMEVAKTSLEIKRKVIERFTKGNLYPYMSFYLRSIRQRFNEYWKNHFSTIGLVGLNECAVNLIGEDIGTEKGRAFAEKVLTFMRETLVKFQEETGNNYNLEATPAEGTSYRLAKLDKERFPEIKCANEELYKQGHPPFYTNSSQLPVNYTDDVFEMLDLQSTIQSKYTGGTVQHIFTGEKIKDLEAMKKFIKTVCEKYTLPYFSITPTFSICPKCGYIEGEHFECPKCKAERMQELERQVKLLEEQLYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIJ9</accession>
    <name>A0A1Y4DIJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57489">
        <property type="protein sequence ID" value="OUO57489"/>
        <property type="gene ID" value="B5F75_01580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="106" mass="12673" checksum="D72B306470920E9E" modified="2017-08-30" version="1">MILDSRPWKKELSKLSQIIYRARFKTKLSESREIAYEKAIFISAYIVRKLFEASKLSYKLKEISCPIKKYPNIKHVNLFNWHNIDQIFDLNNPVRHSLNIKNYATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIS6</accession>
    <name>A0A1Y4DIS6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ORF">B5F75_03050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56838">
        <property type="protein sequence ID" value="OUO56838"/>
        <property type="gene ID" value="B5F75_03050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="3"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="22159" checksum="F7EA0CC800279F19" modified="2017-08-30" version="1">MKAFPIIVSSPSGAGKTTIVDAVLKRNKTVSRVITATTRAPRTGEKDGVDYLFWSIKQFEQAIKKGQMLEWAQVHTHYYGIPKKSVDSLMKKGICPILVIDVQGARTVKAQYPDAAMVFIVPPSLKELKKRILGRNDNTQDIELRLETAKKEMLELDHYDYALLNDDLEEAVDNMAGIIAAEQCRVSRQDLKIKNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ18</accession>
    <name>A0A1Y4DJ18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpH</name>
        <name evidence="8" type="ORF">B5F75_02475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57659">
        <property type="protein sequence ID" value="OUO57659"/>
        <property type="gene ID" value="B5F75_02475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="9"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="19301" checksum="953EC2D7120618F5" modified="2017-08-30" version="1">MNSSDRLAVQRYAAAYNDLSATNEQAQRRAQDLRAAQEALSSVREVMTSPRVTARQKKQAVRAALSQAPETASFVELLIDAKRYPLLDAVTRRVGELLDERMGILRAEVVSARALSPEQKKQTQEALSARYGAKVEASFSVDPTLLGGLKMTCRGELIDGSLQGRLMKLQEELTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ94</accession>
    <name>A0A1Y4DJ94_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57018">
        <property type="protein sequence ID" value="OUO57018"/>
        <property type="gene ID" value="B5F75_04010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="10880" checksum="43C90AEA01B837C3" modified="2017-08-30" version="1">MLGTKIKKEEMLSEAYQQAAKWCNEHQAEMKLEGDYFVVVKTPAPAAPTAEELVQAKEAQMGLTRAVRELVLAENSGASEYVRKQAQEIEAMAAPLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJH0</accession>
    <name>A0A1Y4DJH0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">B5F75_04560</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56470">
        <property type="protein sequence ID" value="OUO56470"/>
        <property type="gene ID" value="B5F75_04560"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="283"/>
            <end position="285"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="454" mass="50551" checksum="192C8CEEB980617B" modified="2017-08-30" version="1">MIILFLNCGSSSVKYSVYDWDQKKSLCAGAVERIGIEGSFISQDRNGYPTFELKRNCKDHKDAINLVIETLTDKEHGVIENINVISAVGHRIVHGGKFAKSVIVDDKVVEELRNIADLAPLHNPAHIMGIEAARALLPNVTHVCVMDTAFHQTMPASSYMYALPRKWYTDYQIRRYGFHGSSVLYTSRRAAVLLGKNVDEVNSIVCHIGAGASVTAVKNGQCLDTSMGLTPLEGLVMGTRSGDIDPSICFHMMKKLNMSADEMYTILNKKSGMYALTGDRFADQRDVRKGAANGDELCKLALDVECYRVKKYIGAYMAALGRLDCIVFTAGVGERATNIREMILKGLENFGIMLDEERNNAADTNKAECCISADNSKVKIFVIPTDEEIVGVQDIVALLAGTYDVYTKFRYIFQEKDYRNKLRDAAFIEEVKKRPFLLKAAVNLPEQLKQELKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJN8</accession>
    <name>A0A1Y4DJN8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56550">
        <property type="protein sequence ID" value="OUO56550"/>
        <property type="gene ID" value="B5F75_04980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000667">
        <property type="entry name" value="Peptidase_S13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30023">
        <property type="entry name" value="PTHR30023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02113">
        <property type="entry name" value="Peptidase_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00922">
        <property type="entry name" value="DADACBPTASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00666">
        <property type="entry name" value="PBP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013164468" evidence="2">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="490" mass="54540" checksum="9B614A9EF2DB53AE" modified="2017-08-30" version="1">MYMKRFSFFALLFFCSLSATAQPLQAVVEKQLQHPVLNGAWWGGLAVYTDHPEQTLFALQADQRLTPASTLKLLTTAAALETLGPHYRFQTRLYASAQPDEKGILKGDLYLQGGGDPTLGSTRVPGAQDWRQVASQWAKAVKKVGIRRVEGSLYADVSAFEGPSIAPKVNWENIGNYYAAPVSPVCFHDNLFKIFFSPQPFDAKRAEVTRTEPKIPQLHLSSFVTTDAKNKRDNAYVYGAPKQYEMEIYGTIPTNLTGFSIQAAMPDPALFAMQALHNALREEGIAVGGRPQTTDQAPDYAQMKLLHTYSSPELKDIILIVNKRSFNLYAEMLLRQLALHAGKKGSVQNGLTELEKFLRQNKLAAPQDAVLYDGSGLSRDNMLTPRVLVNTLAFMTKSPNFSYYYQSLATPDDRGDLLLLRYFLKPKHQVQDVRVKGGTIDGVKTVAGYVYDESGRPIAFALMANNLASKDETILRIHENIIKQLLQVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKI6</accession>
    <name>A0A1Y4DKI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytidine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57438">
        <property type="protein sequence ID" value="OUO57438"/>
        <property type="gene ID" value="B5F75_01310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="162" mass="18290" checksum="CC14B7CB29AA8E98" modified="2017-08-30" version="1">MARRDKTNYYLDLADVVSQRSTCLRRRYGAVIVKNDEVISTGYVGAPRGRKNCSDLGYCIRQQLNIPRGERYELCRSVHAEANAIISAPRDKMLGATLYLAGREVSTGEYISHSNSCSMCKRMIINAGIKNVIVRDTNDAYREINVQDWIDNDESLSGQRGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL04</accession>
    <name>A0A1Y4DL04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">B5F75_02205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57608">
        <property type="protein sequence ID" value="OUO57608"/>
        <property type="gene ID" value="B5F75_02205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="186" mass="20434" checksum="9291049FE1198958" modified="2017-08-30" version="1">MQYLLAGLGNPGTEYERTRHNAGFMVLDAAGQKWGAEWKAWQNLGVYAKVTVAGKEVFLLKPSTYMNESGRAVSSLARFYKIPPQNCLVCFDDVSLAVGKLRLRKSGSAGGQKGMKSVIEQLGTQDIPRLRLGIGPKPEKFDLANFVLSKFPKADQPALEDALSRAVDALEMLFTQGMEKAMNTFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLA8</accession>
    <name>A0A1Y4DLA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA-specific adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57718">
        <property type="protein sequence ID" value="OUO57718"/>
        <property type="gene ID" value="B5F75_02565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="157" mass="17715" checksum="9E12C433B45A7332" modified="2017-08-30" version="1">MKEHAKFLKEAVKMAEKGMLSGKGGPFGAVIVKDGKIIARGCNQVTSSNDPTRHAEVDAIRKACKKLGTFELKDCVIYSSCEPCPMCLGAIYWARPKALFFAADRFTAAKYGFDDEFIYKEVPLPVEKRSLKTFCIDLENKNEPFEKWNEKTDKITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLM2</accession>
    <name>A0A1Y4DLM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tungsten formylmethanofuran dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56301">
        <property type="protein sequence ID" value="OUO56301"/>
        <property type="gene ID" value="B5F75_06710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="68" mass="7552" checksum="FCD00C5014353AD6" modified="2017-08-30" version="1">MPRIEVDANKCKACYLCVNACPKKCLGKSKTISKKGYFPAEMEHPENCIGCAMCYMMCPDIAITVIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLQ5</accession>
    <name>A0A1Y4DLQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57230">
        <property type="protein sequence ID" value="OUO57230"/>
        <property type="gene ID" value="B5F75_00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="245" mass="27034" checksum="0EA3D61DFB6B68EF" modified="2017-08-30" version="1">MVLSLLLGLVCPLHAQIQRTYHYGVVPTENITTFEVNPSTTVLDDSAGISSTQLTLKTYHVINERFNWGVEVPVVRYESPDKSVNGLGDVLANITWTLPAENLFGFGAKMEFFLPTATDKLLGSGQLQASPSAFILLAFPAGFYGAVGYKHYVSVVGDHARADINTGRLRANIGYTSPNQWWVLTNLYYYMDFEHSGMAEFIPELEVGTLVNDGTAFYANASTHAAGNWKTKDWSFGVGFKLLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMH2</accession>
    <name>A0A1Y4DMH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadE</name>
        <name evidence="9" type="ORF">B5F75_01635</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57500">
        <property type="protein sequence ID" value="OUO57500"/>
        <property type="gene ID" value="B5F75_01635"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041856">
        <property type="entry name" value="NAD+_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for glutaminase activity" evidence="5">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="active site" description="For glutaminase activity" evidence="5">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutaminase activity" evidence="5">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="355"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="475"/>
            <end position="478"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="603"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="643" mass="69914" checksum="F6E99C7CE10D20A5" modified="2017-08-30" version="1">MNHFGFVKVAAAVPSVKVADPAYNAAQMETCLRQAVREGVRAVVFPELGVTGYTCGDLFLKPLLLDAAERVLGALLRRTESLDIVFMAGLPVRAGTVLLNAAAVCYRGEILGVVPKTHLPNYNEFYERRWFASAQEWGGGEVELCGQVVPAGPDLLFEAGGMNFGVEICEDLWAVVPPSSRLALQGADVIFNLSASNALTGKYAYVRQLVAQQSARCLCGYVYASCGFGESTTDVVFGGNALIYENGTPLAFSERFSTQAQLVSAEIDVERLRAERAVNTTFRADAAYEAAEPYERVETGMAPAPVLALSRPVSALPFVPKGTALNENCQEIFNIQVTGLATRLAAAHAQTAVVGISGGLDSTLALLVCAQTFAKLDWPRKKIIGVTMPGFGTTDRTYQNALALMKNLGVTIREVNIQKACEQHFSDIGHNPKIKDVTYENTQARERTQVLMDIANQTGGIVVGTGDLSELALGWATYNGDHMSMYGVNAGVPKTLVRLLVLWAAQHETGKKTQAVLNDIVATPISPELLPATAKGHIAQKTEDLVGPYELHDFFLYYFLRYGFGPAKIYFLAKHAFDKKFTPAVIKKWLQVFLKRFFAQQFKRSCLPDGPKVGSVALSPRGDWRMPSDASVQAWLAEAENLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMK9</accession>
    <name>A0A1Y4DMK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_05420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56631">
        <property type="protein sequence ID" value="OUO56631"/>
        <property type="gene ID" value="B5F75_05420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="31"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="106" mass="11693" checksum="C2C1384EF1A6A2DB" modified="2017-08-30" version="1">MSEVILNDSNFETEVLKHKGPVMVDFWATWCGPCRMLGPVVEEIANEYAGKVKVCKLNVDEGTDTSSKYRITSIPTIIFFKDGEVVGQTVGLQSKAALQEKLNALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DML1</accession>
    <name>A0A1Y4DML1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutL</name>
        <name evidence="8" type="ORF">B5F75_01840</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57540">
        <property type="protein sequence ID" value="OUO57540"/>
        <property type="gene ID" value="B5F75_01840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="213"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="437"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="622" mass="68934" checksum="109EE9AB149114FD" modified="2017-08-30" version="1">MSNIRVLDEKTAGKIAAGEVIERPAGVLKELLENAVDAGATSINIDIEGAGRELIRINDNGCGMDEEDLEQSVLRHATSKIRSFDDLTTLQTFGFRGEALYSVAAVSRMTLTSCTGEGAGHRLELHAGKVFSKSPAPAIKGTTVEIRDLFYNVPARLKFLKSDSYERACLLKVIEESALANLKVAYRVHVNGRTVYDLPAQSGPFEQAVIARAKAILGEEVAGSLLFKAFDEGKLNLFLSPADKLVTVRDMQYIFVNRRPIDSKTVQQAIYKAYQNVRPKDRHPAFLVYMTLNPADFDVNIHPQKRDIRFENENRVFGRIMNDAGEVIFGQSRPVDVRLEAPQMTLPPAAQEAAQKLLSPAAPTPMETFAAACAARPAQAFSPKPHFVIKETEDPAEYIARPEGEPSGTDVPSPSAPAPRASLPEETPSWYQGPYHYLGQLQRSYLLFENPQGLVVIDQHAAQERVLFEHYLDAFERRGVKVQKLLFPVHVDLPPSNAETLLSWAAWLKTAGFEVEPFSARTVLVRTMPHMIRFKEDDMKEFIVSLSQVVGDPSKSTETLKRNMVAMLACKKAIKAHDAISPAEAEGLLENMKKCKDGMHCPHGRPCIAQVDMKQLDKLFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN48</accession>
    <name>A0A1Y4DN48_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="7" type="ORF">B5F75_03015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56831">
        <property type="protein sequence ID" value="OUO56831"/>
        <property type="gene ID" value="B5F75_03015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="89" mass="10282" checksum="5C25C5A319687A5E" modified="2017-08-30" version="1">MVLSMQDRKDIISKFQSSANDTGSAAVQIALITERIQYISNHLKANPKDFAGERGLNKLVGQRRRLLAYLKRTDFEKYQKVTQELKLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNP1</accession>
    <name>A0A1Y4DNP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57011">
        <property type="protein sequence ID" value="OUO57011"/>
        <property type="gene ID" value="B5F75_03965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00002">
        <property type="entry name" value="YbaK_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006181">
        <property type="entry name" value="EbsC_YbaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00011">
        <property type="entry name" value="YbaK_EbsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="35"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="159" mass="17563" checksum="D0B6354FEF068F9A" modified="2017-08-30" version="1">MKNKIHKTNAARRLDELGISYELIPYEVDEENLSAVHVAQTLGQNIDQVYKTLVLRGDKTGFFVCVIPGGAELDMKAAARASGNKSCEMLHVKELVPVTGYMRGGCSPLGMKKHFPTYLHEDCILWDFIYVSAGLRGLQIKLNPNDLLRAAQASAVQLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNU2</accession>
    <name>A0A1Y4DNU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57061">
        <property type="protein sequence ID" value="OUO57061"/>
        <property type="gene ID" value="B5F75_04225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="369" mass="41680" checksum="4A91A59BEB84379C" modified="2017-08-30" version="1">MKLTSKWVLWFVLVTVYAAVIGGLFYYNLFKFVFDKKLQNEMVEMVRFRAPTLVQWLASRPKGEATFREAEIMKGLQRNDDRIKSLVYLNYDGSIRWHENTKFLRMSYSDYNNSVGFDTNAVVQAIRDGLPRAILFGNGDYYDMAIPLLAKGNTVAGVVNVTVSRESAKKLIHSSMVRYAVGAVIMILLIGGVLYLFLLLKILRPLGALKDSVEAVSLNNLSLSFPPRKDEIGDVAVSISSLLAKIREDIKSLENVEIMSLEKEQRWWKTILAVTVPKGSRALVIDENNNILYTNFELNMPGKDRIHLLDIFDGRQQEIIQVVGEALENPTKVLRGTVINKNVKCLVKAVQLPDDAGKNRIVLVLEPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNU9</accession>
    <name>A0A1Y4DNU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EBSC protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57071">
        <property type="protein sequence ID" value="OUO57071"/>
        <property type="gene ID" value="B5F75_02880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="27"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="163" mass="17317" checksum="5931824FF9DF1C50" modified="2017-08-30" version="1">MNPVEKVTHYLAQFSLEDRVITLDASSATVALAAQALGCPPALIAKTLSFVLKEGVILLVTAGDAKVDNPKYKAVFGQKPKMPAGDEVEALTGFAPGGVCPFAAKEGVKVYLDVSLKRFKTIYPAGGSGNTAVRLTPAELETASRAEKWVDVCKNWQEHTPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPD5</accession>
    <name>A0A1Y4DPD5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">B5F75_00275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57251">
        <property type="protein sequence ID" value="OUO57251"/>
        <property type="gene ID" value="B5F75_00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="82" mass="9063" checksum="AE4814C864EF4B1C" modified="2017-08-30" version="1">MAVVIRLQRVGKKSQPQYRVVAIEKSAAVGKEAKEVLGQYHPCNPNVAEQVKLNMPRVEYWMKVGAKPSETVASLIKKASAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPL9</accession>
    <name>A0A1Y4DPL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57331">
        <property type="protein sequence ID" value="OUO57331"/>
        <property type="gene ID" value="B5F75_00715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="203" mass="21890" checksum="9E539C15F762596B" modified="2017-08-30" version="1">MRYILYLFTMALLFVGGMMVGNIYLPQRAATLASAVSVPPLSQENPVLQHTNREAAERNLNILDQAMQSCPVVVNEEKDRLVNQIRLLLALEDFELKKARLELEMAKNTDTNRPTAQFTQAVSDYNEAREFAEQLADELFPAPAPQAEPAGETATSSEGTTPSAEQAKQPADQATDAAPATQSAAPADKKPSAATAAEGSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ24</accession>
    <name>A0A1Y4DQ24_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_01480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57471">
        <property type="protein sequence ID" value="OUO57471"/>
        <property type="gene ID" value="B5F75_01480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="69"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="133"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="44868" checksum="E908BB496A17D852" modified="2017-08-30" version="1">MESLKELYKIGMGPSSSHTMGPRKAADAFNRAYPNAVSFKTVLYGSLAATGKGHLTDFTIKEAFYPKPVDIEWDYTTLMPKHPNALRFQALDKAGHVMGEKVVYSVGGGTIRDDETIGQQVNNIYPHHSMAEILEYTSQKRMLLWEYVEECEGADIWNYLQTVWQTMQATMKRGLEKRGVLPGSLNLERKARRYLYKAENSPQYLRRMNNLFAYALACAEENASGGVVVTAPTCGSCGVVPAVCRLVQEICEFEDNTIIRALATASLFGNMAKANASISGAEVGCQGEVGVACAMAAAATCQLEGGDNRRIAYAAEMGLEHHLGLTCDPVDGLVQIPCIERNALAASRALDCATYALMSDGDNRVSYDDVLATMMQTGLDMNKDYRETARGGLARFFKEKVLRIKGDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9U3</accession>
    <name>A0A1Y4D9U3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplK</name>
        <name evidence="9" type="ORF">B5F75_07035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4 6">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56027">
        <property type="protein sequence ID" value="OUO56027"/>
        <property type="gene ID" value="B5F75_07035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="7">
        <location>
            <begin position="74"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="144" mass="15530" checksum="560538995582B0E0" modified="2017-08-30" version="1">MAKEKKIKGYIKLQIPAGAANPAPPVGPALGQHGVNIMEFCKQFNAKTAKMEKGIKIPVIITVYEDRSFTFITKMPPMAVLIIKELGLAKGSGAPHKDKVGKITQAQCEKIAAQKLPDLNTKDIKQAAEMVKGTCRSMGVDVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAC9</accession>
    <name>A0A1Y4DAC9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">B5F75_06105</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56187">
        <property type="protein sequence ID" value="OUO56187"/>
        <property type="gene ID" value="B5F75_06105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO56187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="259" mass="28150" checksum="B088DBA15325F2BA" modified="2017-08-30" version="1">MTILDAVLLGLLQALGEFLPISSSAHLVLLPYFRGMEYQGLAFDVLLHAATLLAVILYFAKDWFYLLKDGLTHPTSAQGRMLWYLAAATVPAGLAGLLLNDWAESTFRNPLMIAGCLMVFAALLWWADRKGAKNETQEITFKTIMLIGCAQALAIMPGVSRSGITITAALLLGLSRPAGARISFLLSTPVIAGAALLEMGQLSAADIHAPLVWGFVSAFAGALAVIGWLMKYIKTHSFDIFVYYRWLLGAAIIVFYFCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAD8</accession>
    <name>A0A1Y4DAD8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_07085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56036">
        <property type="protein sequence ID" value="OUO56036"/>
        <property type="gene ID" value="B5F75_07085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012257">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32479:SF17">
        <property type="entry name" value="PTHR32479:SF17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="434" mass="49459" checksum="FA5D0F3424E89867" modified="2017-08-30" version="1">MTDFFVPQLDPNAPKKHLSSLQTPFGERSVYDSVSFCNRCGSCQQACPTYLLSAQETFSPRGRNQAVRLLMERKITVAQNRALLQELAASCLLCGRCTQACAGKIPTAQHMLELRRALGGRWLPGGLHFLLSCRARRPRLFAFLVQTARVLRRMGAVRLMRMSGLLALPPLSWIRHADDILPRALHEKERKQLLQQTLSPVQNPTLIYLPSLEAQWLMPDLGASVLAQAAQKHSVLVWNAPSGLFEYVYGDLRQSRRLLRRLIRRHQHTAGGRLPVLTDSIDVYLFFRSAPQLFDRWPSLQKQARRFAACVCFVTDILKPRPQKAEQKNVRLDYSALFSREGEVFDRAQKILKTQFKKNFVECWYKDADTPAFGYSFVRPDWAEPICMQAVRSIARTQTGTVFTLSGLSALELGFYLKRFYPHAQADHLVRLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAE1</accession>
    <name>A0A1Y4DAE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56163">
        <property type="protein sequence ID" value="OUO56163"/>
        <property type="gene ID" value="B5F75_05975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="87" mass="9647" checksum="CC564F79AFF50519" modified="2017-08-30" version="1">MQEKEIIQTEEVIEPEILDENGRPISPEPAKDSARPKGDTGGLLGGVFVLAFGFIVTLFVAIFSICILLPLMLLGRLFGMQVRTFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAG4</accession>
    <name>A0A1Y4DAG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56193">
        <property type="protein sequence ID" value="OUO56193"/>
        <property type="gene ID" value="B5F75_06135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="215" mass="23816" checksum="68E0B94E1DDD1ECF" modified="2017-08-30" version="1">MKKKIVLADDHAIVRNGVRAVLENLGKDMEIVAEISNGKDLVEYAQKHKADVYVVDISMPLLNGIEATERIVKHDPQAKVVILSMYDDRVSVEKSLKAGAKGFIVKVSTADEIVDAIEEVAAGRFYLCSKVSKYIVQGFLGKTSSRKRDATGLTPKEKEVLQLIAEGYSSKQIAKSFNLSLNTIHVHRNNIMKKLGIHKQAELVRYAIKEGIAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAH5</accession>
    <name>A0A1Y4DAH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutaconyl-CoA decarboxylase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_06185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56203">
        <property type="protein sequence ID" value="OUO56203"/>
        <property type="gene ID" value="B5F75_06185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR015658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="385" mass="40492" checksum="71D235277A3BA872" modified="2017-08-30" version="1">MDILTSLTKIAHATSLYALTWQQLVMIVVCCFLLWLGIKKQFEPLLLIPIAFGGLLSNIPLAGIAETGGFLRVVYDAGIQTGLFPLFIFMSVGAMTDFGPLIANPKTSLLGGAAQFGIFATLIGAIALSYVHFGDAQPFAFGLKEAASIGIIGGADGPTAIFLTSRLAPQLLGAIAVAAYSYMALVPIIQPPIMKLLTTDAERKIKMTQLRPVSKREKILFPLVLLLLCAFLLPDAAPLIGALTFGNLIKESGVAERLSKTLQNDFCNITTILLGLSVGSKLQASQFLKTETLGILLLGIIAFSIATASGVLLAKLMNCFSKTKINPLIGSAGVSAVPMAARVSNKIGLEYDKNNYLLMHAMGPNVAGVIGSAVAAGVLLSLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAI4</accession>
    <name>A0A1Y4DAI4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56213">
        <property type="protein sequence ID" value="OUO56213"/>
        <property type="gene ID" value="B5F75_06235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="93" mass="9732" checksum="19DE2549C478E96A" modified="2017-08-30" version="1">MKNNKGMGLLGLLISVIIMAVLLSLVLKQYAGQTRRALSLPGITAPAQTSPQKKSAPGAKQTPAPCNGRLVGNICVPTQVNSASLDAFEQMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB59</accession>
    <name>A0A1Y4DB59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56286">
        <property type="protein sequence ID" value="OUO56286"/>
        <property type="gene ID" value="B5F75_06625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="93" mass="10431" checksum="DD1C9DCBA547375E" modified="2017-08-30" version="1">MEITKKDVELAAKLAKMRVSEQEVSIYQAQLEALFKWVAELAAVNTDAVKLTNVNHCAHLRPDVASSHPALAEELRRAFDEEQDQCAKVKKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBA9</accession>
    <name>A0A1Y4DBA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elongation factor Tu</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_07005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56356">
        <property type="protein sequence ID" value="OUO56356"/>
        <property type="gene ID" value="B5F75_07005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP_EFTU_D3" evidence="3">
        <location>
            <begin position="27"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="120" mass="13276" checksum="D81F158D31690815" modified="2017-08-30" version="1" fragment="single">DNVGILLRGIDKNQVERGQVLAAPKTVHPHKHFMGQVYILKKEEGGRHTPLTPGYKPQFYLRTTDVTGELSFKQDMIMPGDNAEIEVKLITPVAMEEGLRFAIREGGHTVGAGVVTKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBB0</accession>
    <name>A0A1Y4DBB0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56453">
        <property type="protein sequence ID" value="OUO56453"/>
        <property type="gene ID" value="B5F75_04475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="73"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="414" mass="45686" checksum="8CA9D2449557F6CF" modified="2017-08-30" version="1">MKKENIFKRIFKRFWKMAWWKKTLIVLLLLAAAWGVKAAFFSAPPAPQFKLARVKRGDIVDIVEASGPINPVNTTEVGALVSGEILKIYVDYNTEVKKGDLMAIIDQTQILAALEEAKARLSSAKESLASADVSYRLAKKNYERYQALYEKDYVSKVNLEEYELAYVNAKSSLNSAQANVVQAQSNLDTAEKDLSNTKIVSPIDGVVLTRKVSEGQTITAGFSTPELFVVAQDLTKMQVEAKVSEADIVKIQPGQEADFTLDGYVGEKFKGVVRQVRTNYVDTSDSTTTSSSSTTYTVIIDVDNSDLRLKPGMTATLTIRTQDKKDVLLVPNEALRFSPSTNANKYENTGVWKMNPGMQQPHRVDVTIGIIATKQTEITGGDVQEGDMVIVGENNLQASTSTQQMGPPRPGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBB5</accession>
    <name>A0A1Y4DBB5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56463">
        <property type="protein sequence ID" value="OUO56463"/>
        <property type="gene ID" value="B5F75_04525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186889" evidence="2">
        <location>
            <begin position="19"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="216" mass="21610" checksum="2977554035714727" modified="2017-08-30" version="1">MKFWMIMALLCAFVTADAQMYRAGGSSRPSFGSRANQEEAEDSSVPGANSTIKTRTFSNYSSRQRDWSKGVQTKTVQTDIQGSKEFKDTSAEQAAQAVKALQGGTPQAPAAKSAAKAAAPAKAGGQQAAAANTSNAAAPAAPAGMADPAAMMQQMQSMMQGLGNMMGGAAAPGGSSAAGGANNGAAGMPAGMNVPGMPDMSSLLKAASAGQQPAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBH6</accession>
    <name>A0A1Y4DBH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate:ferredoxin (Flavodoxin) oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">B5F75_04750</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56507">
        <property type="protein sequence ID" value="OUO56507"/>
        <property type="gene ID" value="B5F75_04750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="681"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="736"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="974"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="1003"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="696"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="700"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="745"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="748"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="751"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="755"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="821"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="823"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="846"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1083"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1189" mass="128708" checksum="EC559B112F054939" modified="2017-08-30" version="1">MAKLVAMDGNGAVSHVAHATNEVIAIYPITPSSTMGEICDAKSAKGETNIWGNVPSVSELQSEGGASGAVHGSLTAGALTTTFTASQGLLLMIPNMYKIAGELTPTVFHVSARAIATTALSIFGDHSDVMSVRQTGWAMLCSDNPQEAMDMALIAQASTLRARVPFVHFFDGFRTSHELNMVEPLTKEQMHEMIDDKLVAEHKARGLNPEHPTVRGTAANPDVYFQEREAVNKFYNAVPGIVKEEMAKFEKITGRHYELFQYVGDADAERLIVIMGSGADVAQNAVEAMQGQKVGVLKVKLFRPFSIADFVKAIPATVKKVAVMDRTKEPGALGEPLFQDVCAAFLTAEAKAKFPTTPLIIGGRYGIGSKDFTPSHVKAVFDNLAAKEPKKEFTVGIKDDLTNLSLPETKLENKAANDIFAALFYGLGSDGTVGANKNTMKIISANGFFAQGYFVYDSKKSGSMTTSHIRFGKKYIRAPYLIQSADFIGVHMFDFLDKYDVLGKAKEGATVLINSPYNAQEVWNHLTAEVQKIIIDRKLKVYVIDASEIALKTGMGSRTNTIMQTAFFGIAGVIPTDKAIADIKEAIKKTYSKKGEEVVQKNYKAVDAALAGLQEVKYPAEVTSKLHTKAPVPAEAPAFVKDVLGEMIAGRGDNLPTSAMPEGGVYPTGTTQYEKRNIAIMVPQWDPNTCIQCGFCSMVCPHAAIRIKAYDGAELKNAPKTFKSADGKADLAGLKFTVQVAVEDCTGCGACVFNCPAKNKENPEKKAINMVHQLDVRENEIDNYAFFLGLKQAEVKTKKESVKGSQMRKPLFEFSGACAGCGETPYVKLLTQLFGDRLAIANATGCSSIYGGNLPTTPYCKREDGKGPAWSNSLFEDNAEFGLGMRLAFDQLNHDAKALLTSAKEGGLKEHASLIDAILNADQSTDAGVEAQRKNVADLKAVLEKGAEKGCEECKRLLSLADYLVKKSVWILGGDGWAYDIGYGGLDHVLASGKNIKILVLDTEVYSNTGGQMSKATPLGAKALFAAGGKTMPKKDLGMIAMTYGNIYVAQVAMGANMNQTIQALAEADAYDGPALVIAYSHCIAHGIDMSKGMGEAKRAVQAGRWILYRFNPEARYEGKNPLHVDSPLGEPTLPLVDYMSGENRFKGLMRDNPELAKELIKRAESEYAWRRDLYKQLAAMQPAEKVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBM6</accession>
    <name>A0A1Y4DBM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56564">
        <property type="protein sequence ID" value="OUO56564"/>
        <property type="gene ID" value="B5F75_05060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="337" mass="35705" checksum="D153E703FDA0D173" modified="2017-08-30" version="1">MKKNILLGCLLLLPALGFGEVVSSISYNPSRMGEYDYLKVADSATLRGGLSTPRMDIATSGTITVSTDTTSRIYDLLSVAGESGSSIDMPRTAFHGNTMNAYSGYESVSTSTPAGLLSKVNAMGGTQTYNQDSYIQTLNAVNILRQKAGTVKGNTLTVEGNNGSSVDLYGEESTNGFYLSGNDIPEPTGAHTNTGSTLNSCQLAWEKRRTNSKPTQEVWLLALKNCIPDSPGGGSGDDDDDATKYKFRQVRSYLRVNNSCSDGTAWCACPNTLSVRSSDVPTAYVESCYSITGSSGQATEGGPCSQKGRYCFNPSGCHLSGIASVGVYAETPIFLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN2</accession>
    <name>A0A1Y4DBN2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="4" type="ORF">B5F75_05055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56563">
        <property type="protein sequence ID" value="OUO56563"/>
        <property type="gene ID" value="B5F75_05055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="18257" checksum="C4232CFAEB100305" modified="2017-08-30" version="1">MPKKESVLVVCTNRKAYHDYFIEDTYEAGLELLGAEVKSIRQKELSLDGSFVRVENGQARVYNMHVKPYKFNSLTEPDPTRVRRLLLNKKEIRKLGAKAELKGYSLVPVEVYFKNGWAKLKLGVAKGKHLFDKRESLKKRDLNREMEQHFKNNIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY9</accession>
    <name>A0A1Y4DBY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Terminase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56657">
        <property type="protein sequence ID" value="OUO56657"/>
        <property type="gene ID" value="B5F75_05555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006437">
        <property type="entry name" value="Phage_terminase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035412">
        <property type="entry name" value="Terminase_L_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04466">
        <property type="entry name" value="Terminase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01547">
        <property type="entry name" value="phage_term_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_3" evidence="1">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="46324" checksum="65F29F1ED9972A88" modified="2017-08-30" version="1">MQVKKLTCTTVFEKNYKNPAPTIVNVGSVRSSKSYSIRQCLIAYALQYAGLRIGVCRKVASTLQHSVIKPFVAALVDFNVYDRENFNKTERYYVFDFKDGNSAQSDILFFGLDDVDKIKSTEFNVIWLEEATDFSFDEYSFLLTRLSAPKPIGWEQNQTILSLNPGDARGWIKTKLLPQKGVCLINSTYKDNPFLSEDYIVSLLAMKETNPRLYKMLVLGEWGQTEGRIFEKWQLYDDESAPKEFDGTVLGLDFGFNHATALVQCSFKENEVYLRELIYKTHITNTELIALMDALGVRKDLNIIADSAEPDRIRDIANAGYICSGIKKTTVLNSIDTVKKYKIFIHRDSKNLQYEFENYEWKKNLDGQYLDNIEPNKQRDDGIAAVRYGVQFYDTTANAMTLVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC18</accession>
    <name>A0A1Y4DC18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56673">
        <property type="protein sequence ID" value="OUO56673"/>
        <property type="gene ID" value="B5F75_05635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="218" mass="24510" checksum="BE10A29CF7B91B3E" modified="2017-08-30" version="1">MTELEKLLQKWNDGVLRGAKIRLARELQVDDSTVSAWVAGRANPPADKIEKISKLFKTSEREVKAAFGIEDKEFSRSLRVTPLTDKNTISLPILADVPAGLPDFSDKDVETFWDIPRWVFPGADFVVKCNGDSLEPKLHLGDYCVIRKTTEPIHGRAMVVKTENGVCMKVIKKLKDGTIQLCSTNPKYKPFIPEELTIVGLIIGSWSRQDKENWLGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC30</accession>
    <name>A0A1Y4DC30_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">B5F75_05790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56132">
        <property type="protein sequence ID" value="OUO56132"/>
        <property type="gene ID" value="B5F75_05790"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="261" mass="28848" checksum="1BD794911806C09A" modified="2017-08-30" version="1">MHPVLFHIGSFELASYGLMTALGYAAAALYLLPKLKKTGIDKDTFWNLIFIAFIGALAGSKLLYIVVSWPELGNTLAEKITNIVRDFRYGFVFFGGMIVSVGALVWYIKKKKLPLLKTADFLIVGLPLGHAFGRIGCFLAGCCYGRPTGMPWGVTFTDPHSLVAPELLGVHLHPTQLYEAAGNLILFFLLHRASQKQHPAGSILIEYVLGYSVMRFIIEFFRGDFRGEYILGLSPSQAIALAAAAGAFILWYRVRKVQRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC94</accession>
    <name>A0A1Y4DC94_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">OmpA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56495">
        <property type="protein sequence ID" value="OUO56495"/>
        <property type="gene ID" value="B5F75_04690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039567">
        <property type="entry name" value="Gly-zipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13488">
        <property type="entry name" value="Gly-zipper_Omp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012282881" description="OmpA-like domain-containing protein" evidence="4">
        <location>
            <begin position="18"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="5">
        <location>
            <begin position="90"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="211" mass="21727" checksum="43C8A70ACB175805" modified="2017-08-30" version="1">MKKVILLCMAVSLLGTACTTPGKRTAWGAAGGAAVGAAAGAIIANNTGGKSETGAIYGALAGLAAGGLLGNYYDKQAKELAAIAEVVKSDSGIQVFLKNDILFATGSSELTAASMQTLTDLNRVLKKYPKNRIVVQGYTDSTGSDAINNKLSTQRAKAVYDFLLGSGLKTMSITYIGYGSSNPIASNATAAGRAQNRRVVLQITANEKDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCA7</accession>
    <name>A0A1Y4DCA7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56794">
        <property type="protein sequence ID" value="OUO56794"/>
        <property type="gene ID" value="B5F75_02820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="461" mass="49040" checksum="B71CDE6A04893FE4" modified="2017-08-30" version="1">MSQQLLNLPRKWLIFTVTATGTFMGTLDGGVVNVALPSIANQFNANIENIQFIVTIYLLAVTCFLPIFGKLSDLYSRKKLYLGGFFVFGVGSILCSLAGSLPMMIFARAVQGLGSSAMMANSQAIIAKAFSGKDRGRALGGIGAVVALGSLAGPAVGGFLIQHFGWPSVFWVNLPVCAIGIWRGLQIIPRFNPKSKMRMDMWGAVFFLISCFSFLYALNDGPSKHWNAPIILGAFATAAVFFGLFYYRERVSKTPFIGLSIFKVRAISYGYAVAVLGFMAVFTNSVLFPFYAADILHLDPVQTGLLILPFPVALALSSPISGLLSEKYPARLITTIGLGLVIAGTLMFSFMDGETSFFYIALAQLIAGCGSGTFQVPNNNTVISAAPKNKLGIVSSVNALARNAGMIMGIALSVAVYAAVQNLFISRGAAPDAAFLHGYQAAMWFGAAVALAGGILSAKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCC1</accession>
    <name>A0A1Y4DCC1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56804">
        <property type="protein sequence ID" value="OUO56804"/>
        <property type="gene ID" value="B5F75_02870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013322870" evidence="1">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="26450" checksum="1C45452E383BC51B" modified="2017-08-30" version="1">MKRLYFLFALACFLLFPAAALAQAPQLHVTAEAEVRVPPDRAAITFGLFEKTDNLRQGAERLNTASSQILQYLRTRGVEERFIQADNLQILPVYTAPAANRPEKLQYEISQTFTVTLEDPSQYEDVLYALLERGVNRITNVSFYSTQLRRYRDQARTQAIRAACEKARLMAEAAEVKLGKLTDLREADASAFWSPRWASNVSQNVLVPEASASEESAPATGMISVRAAVELTYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCC9</accession>
    <name>A0A1Y4DCC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56242">
        <property type="protein sequence ID" value="OUO56242"/>
        <property type="gene ID" value="B5F75_06385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM" evidence="2">
        <location>
            <begin position="293"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="513" mass="55461" checksum="8D132CD947F201D7" modified="2017-08-30" version="1">MLANVCTGAIKGIEGFAVSVEVDIAAGMPTLAVVGLPDAEVRESKERVVAAVRNSGFDFPAKRITVNLSPAELRKSGTQFDVPIALGILAASGQLSEEAREKISRFLVLGELALDGTLRPCAGVLPMLISCKALGKTAVIPPQNVLEGQVSGVPFITPHTLRELADFLEGKLEESAVKMAYVPQPPQEPESELDFSEVKGQALAKRALEIAAAGGHNILMIGLPGTGKSMLAKRFPGILPPLTQEESLEITKIYSICNLMGKSRLLTRRPFRDPHHTISDVALIGGGSTPRPGEVSLAHNGVLFLDEFAEFSRSALEVLREPLENGRVTISRAKETVSYPARFTLVAAMNPCPCGHLGDPHTPCTCSPMQISRYKARLSGPLLDRIDLTVNLNPVKYTDWNQSSEGETSAQIRARVLQAREIQHRRFAGSSTPANAFMTPREIKMFCPLPAGADRILEAAMRKFGLSARSLDKILKTARTIADLAGKEQIETQHLVEVMQYRPLDRKGVADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG6</accession>
    <name>A0A1Y4DCG6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rubrerythrin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56793">
        <property type="protein sequence ID" value="OUO56793"/>
        <property type="gene ID" value="B5F75_02815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01041">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rubrerythrin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin-like" evidence="1">
        <location>
            <begin position="141"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="20506" checksum="423A4EE3829F17C8" modified="2017-08-30" version="1">MELKGSKTEKNLMAAFAGESQATNKYTYYASKAKKEGFVQISKIFEQTAGNEREHAKLWFKALHDNDIPTTAENLLDAANGENYEWTDMYATFAKEAKEEGFDKLAYLFEAVGKIEKMHEERYRKLLHNVETQEVFKKAGIVMWECANCGHIHIGEKAPEVCPVCAHPQAYFMIHPENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG7</accession>
    <name>A0A1Y4DCG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiamine biosynthesis protein ThiF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02835</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56797">
        <property type="protein sequence ID" value="OUO56797"/>
        <property type="gene ID" value="B5F75_02835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000849">
        <property type="entry name" value="Sugar_P_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002808">
        <property type="entry name" value="Hexose_phosphate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="36"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="453" mass="50240" checksum="867E9DFA22F2898A" modified="2017-08-30" version="1">MLRKFIDWFKPLPDAAEKITDPQEITKQYKRWRLRLFISAYIGYAMYYVTRQNLNPIAHVFKAETGITNDQFGLMVSISLIAYGIGKFVSGMLADKSNIRVFLAFGLMASSVINLFFGYLTSFFLLVLFWTLNQAFQSMGFPPISRIFAYWFSPKERASKWTLWASAHTVGISIAAIIAAAILKLMDVTPLIHWQYVFVLSGILGLITSFYILRSVTDTPASVGLPPVEEYTGCQQLVTKEANEGESYWTLLRKYVLTNKYIWILSVAFLCVYFVRYVTLSWAAIFLDTRELSKASIPLIFTLNPLVGALGGITAGILTSKVFGGRCTPSNVIYFVLLAISAYGFYLFAGPDHLFLTGFFIAALGFFVDGPQNLINVQISLLTTKESVAAACGFCGLFGYVGGFLAGSGASFILEHWGWAGVFNACIVSCVIGVLLVMTAWKKENRDISAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI9</accession>
    <name>A0A1Y4DCI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56595">
        <property type="protein sequence ID" value="OUO56595"/>
        <property type="gene ID" value="B5F75_05230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029465">
        <property type="entry name" value="ATPgrasp_TupA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14305">
        <property type="entry name" value="ATPgrasp_TupA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="53"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="373"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1201"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1682" mass="194096" checksum="3E4F542EADB38CAE" modified="2017-08-30" version="1">MKKKNKSGIKSNKTVVNRTKKAKPAFSSQPAQTTGPAARVVVQNHIGYTPKVSVIIPVYNVETYLRECLDSVVNQTLKEIEIICVDDGSTDHSLEILKEYAAKDSRITVLAQPNCNAGKARNEGLAVAKAPYVGFVDSDDYLAPDMYQKLYDKALRTATDICICEFNILNTKTQQIVSKSGISHSFLDKFQVNSNGALLIAPQTPVLQLTNPAPWNKIYSKQFLNHHHIQFQSIISTNDLAFTCTALCCAKLIALVPEALYYYRTNTCKSLTDKKDGNVFCFYEAIQELQKRLEQRKKLKAFFQSFLNASVSCYLYNFNKVNNASKDLLRNLFITEGFARVGLCKQTIGLLYFTEHKRKCELFSHLTSQPAVSILMPIYNVSQYLKECLDSVINQTLKNIEIICINDGSTDNSLDIIKQYAAKDVRIRYIDKPNAGYGQTINCGLNAATGEYIGIVEPDDFIEPEMYETLYTKAKEMDLDIIKSDYAIFTGEKEHRTFTPRVLSNNAAVYNHITNASENTDLFKISNINCNGLYKRSFINENHIRLNETPGASFQDNGFWFQTFSLARRICFIKGSFYMIRRDNPNSSVKSKGKVFCMCDEAMFIHKFLKRDPSLEKKFMGIFWNRMFGNYLWTMNRIAPEFKQMFLSRFRQDFKQAKEDGELNQKFFSKPDWEYINKLINGQLTSDIRKKLSDWYQKVTGKYLNLDNPRTFNEKTQWLKLYDSTPLKTRLADKYLVREWIKEKIGEQYLIPLIGVYDKFDDIDFDKLPNQFVMKCNHGSGWNIIVKDKSKLNLAEAKQKIDTWMATDYSTRWGFELHYRNIVPKIIIEKYMEEVATALYDYRFFCSYGDVKQIWLDVYSGTPNHKRKIYDRNWNELNITVKWPRLETPVEKPQKLADMIRFAEILSKEFSLVRVDFYLIGNHIYFGEMTFTSMSGIGQFNPEKEDLKLGNMIKLPALAYNLETGEYYKLPKKSRIKPYVFFPYYLCKKFFLNKQKEKYTKQQVRAELSGIRLDIKNVGQAQNAVEIYTTEKLSQPAWFSNAQGQGQVLESCRPHLRFNIKAVHPGKLSLVFRGKDRRFGKERIAAWVDYTSIKINGKELLPRPVPVWHDKPFRYEMPVKDGQTVQIELWQHPHKYSRAELKDLVLKLFAKNDYVKAHVEAILKDCSAFIRPEDKRPARWFSVTNTGVQKTVYILGLKLTVQNKQAALRQLLQQQQALLQAVQAASGKNNALEQRYAALASQLTVVQHEVQQAKLWIKQTYEAFPTVNKQLSNAQDALLSQLVTEKKVNRLAAITSVELKKQRKHNQEMKQMLSKFVADTQVDLRYLRNMDVAKNERLQQASKQLSQQMRELFQKQDEQLADMQTLLASGENTLQHLKGIDVAEAQHLKQTEEELTQRIAEAAGAQSELLSSVSAALRKQQEEGLQKTGNLYLSLEALNKAEQKTQAELQKQLRTLQDKSLRQYHELNFADLLHDSTRHSLWLKDKNFSLYGWAANYSFIYTLFRILDKVSPRYILEMGLGQTTRLTSQYVAYKNPAATLDVCEHNQNWIDLYTPELPHSEHIHVHHLELEYFDFEGKPNDKYKDIAKVTGNTKYNLIIVDGPVGGGKNFPRSNIVDLVPQNLAEDFIIIFDDAERAGEQKTIEQTKARLAENGIVFATQQRNGAKSQFLIFSQSMEFVQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK8</accession>
    <name>A0A1Y4DCK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56837">
        <property type="protein sequence ID" value="OUO56837"/>
        <property type="gene ID" value="B5F75_03045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="137" mass="15032" checksum="856AA743B60D4921" modified="2017-08-30" version="1">MEGGKYKEALSSCSKAYELYQKNMAYAKQHKVAVRAAVASSNMPFITDPIILFPDLQEDVIFARVMKGDLKLSQALKENASLTGQGGLIGFLRGANKRMPNAFSYVTESFRNWKGCSKALAEAQSEVAVDPAQFCVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK9</accession>
    <name>A0A1Y4DCK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="11" type="ORF">B5F75_06880</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56332">
        <property type="protein sequence ID" value="OUO56332"/>
        <property type="gene ID" value="B5F75_06880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="445" mass="48841" checksum="2139333DA1A3411C" modified="2017-08-30" version="1">MANNTVANIFNAPELKKRLLFLIGALAVFRIAAAIPIPGINTDVLKQLFAAHQNGILGFMNIFSGGALGKFSILALGIMPYINASIIMGLVRGAHIFPALDRMHKEGESGRRKENQITRIFALFLALLQGAMMTFAITKVEGAGGVSAVVNPSFMFFVTTVLTLAAGTMFVMWLGEQITEKGVGNGISLIIFAGIVDRLPGAIMEVVNRVQTEEMDFFMALVIFGAAVVITALVVWLETAQRQIPVQYAKRQVGNKTYGGQTSYLPLKIDQSGVIAVIFASSVISLPLTIASFNQEAPWAQKMLEAMNHSSWLYMLVFSALIIFFCYFYNSMTINPSDLADNMKKWGGFIPGIRPGEPTKNYIEWVMNRLTFCGAIFVCLIAVLPDFFRAEFNVDFYFGGTALLIVVGVALDTVGQVQAHLLARNYEPLMKGSKRIKGRWFNVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCL7</accession>
    <name>A0A1Y4DCL7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56847">
        <property type="protein sequence ID" value="OUO56847"/>
        <property type="gene ID" value="B5F75_03100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="22706" checksum="EFC824F760E2DAFB" modified="2017-08-30" version="1">MNICSYIIIIIVFNFFKHFIFILSRERKIVYYLGSNLQKGVYMNKQGFTLIEILVVVLIIGILSAIALPQYESAVEKSRMSEALINLKAITDASQRYFQANPNEGIIDHKNKIADVDLRGGTWDNSGKVYTTDLFRYELGTASLGRTVAYRSDNLANAKNSYIYYVWQLPDLGQGGTLKGCSVGREDPEIGEQMCKFFLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCR3</accession>
    <name>A0A1Y4DCR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56954">
        <property type="protein sequence ID" value="OUO56954"/>
        <property type="gene ID" value="B5F75_03665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="88" mass="9994" checksum="7F0DF9168A56B383" modified="2017-08-30" version="1">MIIKVRLIPTTGRNEVISRIGSVLRVKIKNKKVDDDAANAIMRTFLADFFNVHEESIIIVKGAKGKEKTVEVRDKSEEELRKIMDSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCV5</accession>
    <name>A0A1Y4DCV5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">D-alanyl-D-alanine dipeptidase</fullName>
            <shortName evidence="3 4">D-Ala-D-Ala dipeptidase</shortName>
            <ecNumber evidence="3 4">3.4.13.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase M15D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3 4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56947">
        <property type="protein sequence ID" value="OUO56947"/>
        <property type="gene ID" value="B5F75_03630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01924">
        <property type="entry name" value="A_A_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026671">
        <property type="entry name" value="AA_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013368388" description="D-alanyl-D-alanine dipeptidase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR026671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="208" mass="23720" checksum="232DDC237734337E" modified="2017-08-30" version="1">MKWKTLLALMLLAAPLAAQEAKSLEQAGLVDVSALPGVRVFIDMRYATPHNFTGQKIYDSAKCYLHQDAARALQHALRLAAREKEPFTFCLWDCYRPQSAHQKLWQAVPNPNYVAPPAKGSRHSRGMAVDLTPCDFTGNPLPMPTDFDSFSERAHMDFYDLDPDVLARRETLKKIMTAAGFTYTRTEWWHFDKTGWKQKPLLDIPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCW3</accession>
    <name>A0A1Y4DCW3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56452">
        <property type="protein sequence ID" value="OUO56452"/>
        <property type="gene ID" value="B5F75_04465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="24"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="314"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="408" mass="44104" checksum="D3A96F90F272FF7C" modified="2017-08-30" version="1">MWDSFYAIFKISLKAIFANKMRAALTSLGIVIGVSAVITMLAVGSGAQKSVTDSVARFGTNILFLRQPWDLDESISSPKDVTMDDVYAIRELDGVAAAAPYITTSFDVKYSNTSVALSVLATDPDIFLTYDWPIESGRKFTQREVNDYAQVIVLGASAAQTIFSDVDPLNKTVVLDNIPFKVVGVIKKTGQSGMGFDMDEGALIPYTTGKVKMNAGWNKSDRRALDRVVIKVADFNTIENTKVDIQNAVRNTHRIHPLGKDDFQLDDFASFIEQAKTMGKTMSILLGAIGAVSLIVGGIGVMNIMLVSVTERTREIGIRMAIGATSWDIRLQFLVESVTLSCIGGLIGIILGVIITLLVAAHSTIPAELSLSAILLSVGFSAATGIFFGFYPAYKASKLTPIDALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD24</accession>
    <name>A0A1Y4DD24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57034">
        <property type="protein sequence ID" value="OUO57034"/>
        <property type="gene ID" value="B5F75_04090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013254908" evidence="1">
        <location>
            <begin position="25"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="425" mass="47969" checksum="AEFD61373B227E53" modified="2017-08-30" version="1">MLKRILLGSLFILSSLGTPLQAWAQKQLVPALRAAGAGSVKKAAGASVLHWAPPVSVKGPFSYVPPVQISLQQLESLSAAVNRSVLLQQSRRGTLRELDEIEKFIFSNAPQALRLQAVKFLALGFTAEQARLFLDWYPFLTTNTRFAVENNDWLLRIAPNFKKQAAYVMAHQADIHAALQITEIDRPGLLAQTIGPENRLILVGEVHGRANLQAEMAALLRQYHARYPKRKIVLFSEFLPSSHPSFWQAGQAVPADFFEKNPDFANEIYRLGQSLSMDIYGLEDIRFTYQKTVELSQLEFTVANTSFRVMPVRNKYWEGIIRRVMEQTLRQTPDAVFFVYAGNKHISKSIAESLARMLQDKKPFCIELRNGFQSGFLGLLQGKTPYRMAEVDKPYLMTWKKDSNYSSVLGFDAQVLLPFETPAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD28</accession>
    <name>A0A1Y4DD28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57033">
        <property type="protein sequence ID" value="OUO57033"/>
        <property type="gene ID" value="B5F75_04085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010992444" evidence="1">
        <location>
            <begin position="24"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="471" mass="53072" checksum="2B9AD345D13F130B" modified="2017-08-30" version="1">MGKFFRILLLACCVVGAGVPVWAQKKAVPAVRALTAGPKAVAPQAGRLPGAAGKVVSPSVAKVQALQSGLGSAEVASWSDPAAVQGIFFNKKTTSDSKNWKQLLDASLKKIRLFAKPKKKSSVIADLTALPEEVTAGKAEGLQREVYESYKAVMDLWKARFAPEEDIPVLRAIFMPQLTPSETALKTNKLSLFFSRGFADKSDWLRKYPGQGKNELVRYQGEDEISYLASRLSKEKLVFFGETHHHDEIQYNLASLLNEIRQQNPNRRIVLFTEFIDLPPAQAGSRNTIATYYRRVPETPLEPITLKHSDQIGYALSFFFVALMRNVEVYPLEDPTQFKMFHQNMTKAEFLSLFALSERNKIWARVIEEKMTEIRKQDPDALFLVYAGVGHTSWLMPFALPKFFAGEHPVVLDVTSEVPSRHSLLYHVWGKEDPFFVRNHITSSLYYWTGENARLLGRQVGFDYAWAVPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD35</accession>
    <name>A0A1Y4DD35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ORF">B5F75_03575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56936">
        <property type="protein sequence ID" value="OUO56936"/>
        <property type="gene ID" value="B5F75_03575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="6"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="18"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="615" mass="68044" checksum="0FD75308E2FA0CE4" modified="2017-08-30" version="1">MNNTREDVRNVAIIAHVDHGKTTIVDALLKFAGEFKVKEDQAQDTVLDSNPLERERGITILAKCTSIGYKGHTINIVDTPGHADFGSEVERVLRMVDGAILMVDAVEGPMPQTRFVLRKALALGLRPIVVINKMDRDHVRPSEVVDEVFNLFMELGATDEQLDFPIIYASGRAGWASLKMEEKGKDIAPILDTILEHVPAPQAMPNAPLQMQVTMLDYNNFLGHVGIGRILAGSIQKGQPVTLIHPDGTTTNAKAVKIERFLGLGKVEVESATAGDIVSIAGLEGVDVGDTICRPDALKPLPPLAIDAPTMSMDFMVNDSPFSGREGKFVTSRHLKNRLEKEAQTNVGLRVEQLEGEGKFKVYGRGELHLTILIENMRREGFELAVSSPEVIYKEENGQILEPMEYLILDIKSEFQGPVFTMLGTRAAKLENMVSEGEDRLRLEYLIASRALIGFKNEFLTNTRGTGIMHHSFKGYYPKVNLPDLRRNGVLIAKEDGETTPYALFALENNGELFLGPGVKVYAGEIVGQNSRSNDLVVNPCKAKHLSNMRSKASDESYVLTPPRVMSLEQAVEYIAPDELVEITPTSLRLRKKILSHLLRKRTERAAEMAEEEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD39</accession>
    <name>A0A1Y4DD39_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_02775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56785">
        <property type="protein sequence ID" value="OUO56785"/>
        <property type="gene ID" value="B5F75_02775"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="39"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="424" mass="47240" checksum="601FAA2B35ABE209" modified="2017-08-30" version="1">MGHFLLFLTNLIFPFAALGVVVGFLLSPRRGLLKHLGQELKERFGLEEEGEIPQKAIWLHCASVGEVMSMKEVIARLKDFYKRDILVTTTTEAGKETALKNPNISKALLAPLDFYPSCKRFITLAKPYRLFIVEREIWPNMLQAAHQAGVPAALINGRISAKSTRAYKCVRPLFKQVLGTLAFAALQTQQAAQRYEELGLPKDHIFVCGNVKYDTLNDRPAKTAEVNKILTALGWSGKQILVCGSTHPLEETMLLRAAPEFVKKGIKIIFAPRHLERKPEIEMTLRQSGLRYAFVSQQNFNKETDILCADVMGLLQSLYACATLAFVGGSVERRGAHNLLEPAILSKTVLFGKYFYNAPLTAQALLENGGGVLVDESNFKETVLRLLADPAQLENMSDKARKAALSFKGATDKIMEVVKNYERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD56</accession>
    <name>A0A1Y4DD56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57064">
        <property type="protein sequence ID" value="OUO57064"/>
        <property type="gene ID" value="B5F75_04240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012441165" description="T2SSF domain-containing protein" evidence="7">
        <location>
            <begin position="26"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="374"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="540" mass="60870" checksum="671B43C06F3F8914" modified="2017-08-30" version="1">MTKKLYAFLLGVLLLAAAAPAPLQARALGQQDLARIQCAQEKMRILAEFFDVNLETEKKVYTLPNVCGASAGRTVKMPEWFATELERMDKNKVVYVPNEGTYSEVDLWRQAFSNVYLFLDRAAKSLDPSQPVVLEQLSRGFVGNRINLMATLDRLNKDLLRGNQLLIMKDSMDGRARSMLSTFELINNEFFSTIESFSSPIAQREDKYRQSVMAVVVLSNHLFSQFLGTSIPTYPPDPKIYRTTTADRMVSLILIVLGSSLAGLAVYLLLENKRENILRLVEEYKQKSVVWAEDFNRQFVTIDIKYIVFGTVGLFALFGLFLGLMVGGFTGVFVFLLVVFMGGVVSIRMPTAVLDALKKSRGKRINKQLMDALILLSNSLRSGMDIVQGFELVSKDMLPPIADEFGLVIKNYQLGTPFEKALDGLSDRVESRMLSYIIKAIIIQRQVGGNLTVIFARLVENIREESKLEEKLQAMTAQQKIQSIVVSIMPFVMMLVMFIFNPSQMISFYTSPMGIFLFLFCIIWIGIGMKVLQKMGEVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD63</accession>
    <name>A0A1Y4DD63_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="8" type="ORF">B5F75_03725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56966">
        <property type="protein sequence ID" value="OUO56966"/>
        <property type="gene ID" value="B5F75_03725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="195" mass="21706" checksum="C20B2B7B2EB6DFE1" modified="2017-08-30" version="1">MIIPTIIEKNVGYDIFSRLLKDRIIFVGGREGEVDTASANMIIAQLLYLDADDPNREINLYINSPGGLVTAGLAIYDTMQFIKAPITTICMGQAMSFGAVLLAAGSKGKRYALPHARIMIHQPLIWGGGISGQVTDIEIESKELRDNKEHLLDILAKHTGQDKEKIRRDSERNYYMSAQEAKEYGLIDEVLPLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB0</accession>
    <name>A0A1Y4DDB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56622">
        <property type="protein sequence ID" value="OUO56622"/>
        <property type="gene ID" value="B5F75_05370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="565"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="680" mass="76934" checksum="E9C0F48021704744" modified="2017-08-30" version="1">MALDNNQYDGHGDIAQFLEKFKEQTFAAASSADKGYSPREGSVPAKPAQYERSFEKLEKKIVELEERFEASATQNQLILSELARTREAMERQKDKDAFLEHLSRTIANLKASVENLSRAQQERFAYREPDVQRSFDPVPPAFQAGDESHTAIYHYQANAPHTGRTHAEREEKERIITSLRQKASQLKAVNSALDREIKKAQQEKMEALKKSAEQAKEILSLRDQLTAAEERFKSFDFEGRIISIKQEYQQKVSSLENQLQAMSDTCMKQVEEIESLKAENVKLHKAAAEKEEALARLEAKEKELVALKNEMAQLADNNSKRAQKQLAVFSERLRALEGQRDGLAAELEQAQASLDAVRQEKDLLEKNFKELVEKINNNDAVIEQLKHKIEVLGQQNEELTHHNETLSEHNAALQSANETLSREKAEMTAHTEHLAREKESLSARAQQLEQESAQMAERSEHLTREKEQLASRVEFLAREKDTLDIRTRQLDSEKENLSKNVETLHLEKEALEREKSALSLQSTRLQKRTEELEGEKKELAKENQQLRNQSAALLAARLVQEKERAAKEETLRKAAAARPAAPKPSVANAQPAAPQAPVQTAAPAAPALEKTPQTAVPLSEKPVEMNQAVKSKVMTEADLPEIKVADPVPQPEPLFDGEDFLEKTDSFIGRMKWSIFREDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB1</accession>
    <name>A0A1Y4DDB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M15_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57016">
        <property type="protein sequence ID" value="OUO57016"/>
        <property type="gene ID" value="B5F75_04000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039561">
        <property type="entry name" value="Peptidase_M15C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13539">
        <property type="entry name" value="Peptidase_M15_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M15_4" evidence="1">
        <location>
            <begin position="59"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="129" mass="15034" checksum="6B0ECD7D8F358A70" modified="2017-08-30" version="1">MPVLSSVSQTRLATCHPDIVAVCRELIKQYDFSVLCGHRTREEQNKAFSCGASRLQYPQSSHNKTPSHAVDLAPYPIDWNNLARFREMWHRFDALAQLMRGREEITSEFEWGGEWDTLKDFPHIEIKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB3</accession>
    <name>A0A1Y4DDB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57067">
        <property type="protein sequence ID" value="OUO57067"/>
        <property type="gene ID" value="B5F75_04260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="162" mass="18305" checksum="EA42C54D5C5CFF04" modified="2017-08-30" version="1">MNKFRRKCGGQVTAELMLILPVFMLMVFFVLEYGNIAYHTIIANHASYEFARIGSLVAVKKPSGRPDRTVITQKINQAKQKVFGTKAAGIGVNVKVETTGTDPMYRRHRHEDVIVTVTYPVRLMFPGTSYVLASEPRREGVRRIQAVTRMPIEKAYQSSDTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDE2</accession>
    <name>A0A1Y4DDE2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56662">
        <property type="protein sequence ID" value="OUO56662"/>
        <property type="gene ID" value="B5F75_05580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="93" mass="11404" checksum="F2BC3DF6983867D1" modified="2017-08-30" version="1">MNKLHLPLTYHWFDEIESGRKTCEYRRFTEGWSKRLSRLKKSDLVVFHRGYSSRTITRRIVNIRLVDGWNLPNEVYQFFGRPNESRFFEITFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDE5</accession>
    <name>A0A1Y4DDE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57056">
        <property type="protein sequence ID" value="OUO57056"/>
        <property type="gene ID" value="B5F75_04200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="232" mass="25198" checksum="B7FF55BB1EC6806F" modified="2017-08-30" version="1">MPMNKKKKVTVLIADDQTLFREGIKDVLTGEKWIEVVGEAADGLEAVAKAKKLKPDVVLMDIKLPKMDGINATRQIRQACPEVNVLMLSSFEDEAHVLDAIQAGANGYLSKMLPAAELVNSIKTFTSEGLMIPQQLMGKLLHGLRKMGNNGMPSQATLTKTEIKVMDYLGKGLSNKELAKELNCSVKTIKNHLNSAFHKLGVSSRTEAVVKAIEKGLISSEGTIVPDDNDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDF0</accession>
    <name>A0A1Y4DDF0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_17 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56672">
        <property type="protein sequence ID" value="OUO56672"/>
        <property type="gene ID" value="B5F75_05630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="5"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="58" mass="6666" checksum="FC19472F1B433F43" modified="2017-08-30" version="1">MKNQFLTVAETAKILRLSPRRVQELAQAGRLDAMKPFGRILIKRKSVAQKLGMREEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT0</accession>
    <name>A0A1Y4DDT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP reductase</fullName>
            <ecNumber evidence="4">1.7.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanosine 5'-monophosphate oxidoreductase</fullName>
            <shortName evidence="4">Guanosine monophosphate reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">guaC</name>
        <name evidence="8" type="ORF">B5F75_00390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>IMP + NADP(+) + NH4(+) = GMP + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17185"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.7.1.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.7" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57273">
        <property type="protein sequence ID" value="OUO57273"/>
        <property type="gene ID" value="B5F75_00390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902560">
        <property type="term" value="C:GMP reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003920">
        <property type="term" value="F:GMP reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006163">
        <property type="term" value="P:purine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00596">
        <property type="entry name" value="GMP_reduct_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005993">
        <property type="entry name" value="GMPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000235">
        <property type="entry name" value="GMP_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMPDH" evidence="7">
        <location>
            <begin position="9"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="4 5">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000235-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="367" mass="40366" checksum="CAF33A1355084CDA" modified="2017-08-30" version="1">MRIYDDIQLDYCDVLLRPKRSTLASRSEVIVEREYTFKWCPRSLTATGIVAANMATTGTFEIAKEMQKLRLMSALHKHYTAQELLQFLKDNAQAFGNNDLLFVSSGVSDADYEKLKQVMASKLINNICVDVANGYSPYLINYIRKIRKDFPQALIMAGNVVTGDMCEDLILNGADIVKVGIGPGSVCTTRKLTGVGRPQFSTVIECADAAHGVGGMICADGGCTVPGDVCKSLCAGADFVMLGGLLAGHTESGGEMCTKSFQTGEVEMIDDKTCAMRIEEKQYKKFYGMSSEYAQDKHYGGMKKYRASEGKVVEIPFRGPIEHTLLAILGGIRSCMTYIGAKRLKDMPKCATFYRVNRQLNTIFGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW2</accession>
    <name>A0A1Y4DDW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57303">
        <property type="protein sequence ID" value="OUO57303"/>
        <property type="gene ID" value="B5F75_00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="87" mass="10013" checksum="B1CEB267B265F6F6" modified="2017-08-30" version="1">MNKDDVIRHLTRHVLDKKQAKMSVDKVFEIIKHGLKRDGKVVISNFGSFHLKTARPVTRRNPKTGAKVQVPAKQKVRFKPSENLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX3</accession>
    <name>A0A1Y4DDX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56842">
        <property type="protein sequence ID" value="OUO56842"/>
        <property type="gene ID" value="B5F75_03070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="20855" checksum="C5F9588F5E029673" modified="2017-08-30" version="1">MNWTDLFRFSPRASRQEYAFVSLCTQGISLLFYALQGRFASEGLSWIQFILALAFGFVSAVLLWAVFWVGLAVSFRRMHDMNLSGLWYVGYYVAVVCVGVVFSEIWWVATVLGVAAMLFLCLKKPSSSNRFAAAAPAFMPGVFSKRGVFAAAVVACILLSVGQVALSRWQLASAQKSFPARQIQSVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE71</accession>
    <name>A0A1Y4DE71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57397">
        <property type="protein sequence ID" value="OUO57397"/>
        <property type="gene ID" value="B5F75_01085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="5"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="21105" checksum="A5AB9E9AA52459CB" modified="2017-08-30" version="1">MKHKKIALTGGPNSGKTTALSILKETFGPKVELVREAATMIFSGGFPRQDNSRPHIEAAQQIIFYATREMESLAEESSDAPLIVCDRGTVDAAVYWPGGVEDFFARMGTTLEAELARYDAVLHLSPPSNPAFYQSTHVRTESLQQAFEIDRKILKIWEKHPNRLVVGGTEHFFEKAEVIKNFVEKIIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE96</accession>
    <name>A0A1Y4DE96_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57205">
        <property type="protein sequence ID" value="OUO57205"/>
        <property type="gene ID" value="B5F75_00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012938052" description="Peptidase_M23 domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="4">
        <location>
            <begin position="286"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="388" mass="43628" checksum="0399AB04E77D645A" modified="2017-08-30" version="1">MAKILSVFLALVFCTSPLFCDEAADRKREIEKLKNEAAQKERELKRYREQEKKISKEISALEDKKARAERLKNQVESDISYVEQNLLSIEDKRAALERSMPMWQGVVEEELRNYYFTPSCPYCPGGYSLEQEIFVDRMLTHKAAFAAELKKENTEAKKKIHTFEERNKKLLAQSSQIKKEQAVISQSFNKKKKDLDVTKRKVAAVRKEINELNKSAEELNRLLASFERKRKAADAKKAAASKTSSKKTTGPKIDVPRNSLPWPAVGKVLSKFGKEYRSDLNTWIFRDGIKIAAKAGSPVRTVAEGSIIYAGPFRSYGNVVIADHGKGFFTIYGFLQQISVSVGDKLPQQGVIGTAGKDTQASSGTGQSAVYFEIRQGTTAVDPLNWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG1</accession>
    <name>A0A1Y4DEG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57285">
        <property type="protein sequence ID" value="OUO57285"/>
        <property type="gene ID" value="B5F75_00460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="255"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="327" mass="36377" checksum="905C1A41C6C9BF74" modified="2017-08-30" version="1">MDITTLNKQVQQESIFLQDLKREVGKVIVGQEALLEKMLVALLADGHILIEGVPGLAKTLAVKTLAQAIHAQFQRIQFTPDLLPADITGTLIFNPKDGLFYPKRGPVFSNFVLADEINRSPAKVQSALLEAMQERQVTIGEQTYKLPSPFMVMATQNPVEQEGTYPLPEAQVDRFMLKVLVTYPTKEEEKMILERMASHQTIEVNTNVTPEMILKARAVTDSIYVDDKIKNYIVELVFATRDPKAAGLEKLASFIAYGASPRATIFLTQAAKAYAFLNGRGYVTPEDIKAIGLDVLRHRVLLSYEAEAENISSDQIVKQIFDAVDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI1</accession>
    <name>A0A1Y4DEI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57466">
        <property type="protein sequence ID" value="OUO57466"/>
        <property type="gene ID" value="B5F75_01450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="250"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="386" mass="44249" checksum="EB4EFE64EFE9EBDC" modified="2017-08-30" version="1">METDLIKDMKKLLLLFILLATLPCAAQRHLLKEAAAEGVFKKALGKTAGEDILRQARVVQGKILPGGKMPRAAVPSDLEKYIFKQVRPTPIGYLPVLFLEPSQMPIEDISLLYKRVMQSFQAFKKEMDVFLYYQSKPSERREISSAEQAMWSEKIGLMNAQLLQLKNLISQHDPAYQAAREYMVFAAETVNPMLRGILEQRTFARTDRQYTSTEFFLHTPQALKETAWTEWLPLSVRTNQAARRLPEGLRMAVLNDEPSVLAAMQREHQNRFCPTWELATYSEADDLLQAVRRGAEFDVILTDLIVPGGGGYYLVSALREKGFNGAIFGLSAYPEESRMGWNMFQRGFDGMIPAPIGFEQDRNWPRLVMKKLQNYFYYRDLNGWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER0</accession>
    <name>A0A1Y4DER0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56209">
        <property type="protein sequence ID" value="OUO56209"/>
        <property type="gene ID" value="B5F75_06215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="262" mass="28708" checksum="82098763CAC24EAD" modified="2017-08-30" version="1">MPSVIEAENLQFAYVRVPVLEGVSFSVQAGDYVGIIGPNGGGKTTLLKLLLGLEKGKGQIKLFGQPLDAFKEWYKIGYLAQKSPVAQSRFPVSAEEVVLMGLSARHGSGVSVGELKQVHEAMQKTRTRDYAGRIFHDLSIGQQQRVLLARALVSNPQLLILDEPSTALDPESREMFFNLLGDLNARQGVTILLITHDTGEVGKYISKFMYIDKTLVFYGTKEEFCHSPEVAAKLGPFAQHTIDHLHNHGQCPLGGMCGEANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER4</accession>
    <name>A0A1Y4DER4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-binding protein B5F75_01985</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57566">
        <property type="protein sequence ID" value="OUO57566"/>
        <property type="gene ID" value="B5F75_01985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00636">
        <property type="entry name" value="RapZ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="285" mass="32217" checksum="4EAFA3C723DB2DF2" modified="2017-08-30" version="1">MADNKRRIFIITGLSGAGKSQALKIFGDFGFYCVDNLPLALFKNFTDYIKQSGERKDIALGIDVREGGRLKDMPKILNSMVADDFIVRVIFLDASEECLIRRFSETKHRHPIHKKLAAAIAHEREVMSPIRTMADKVIDTSDLKLGELKEKLSALLGLTRDGDMQISVVSFGFKNGILKDCDIVMDVRFLPNPFYIPELRDKTGLDKEVQNYIMSFKETQEFAEKFADLIKYLIPKYIKEGKSYLTIAMGCTGGKHRSVFMAHELAQRLAKAGLNATEFHRDIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET3</accession>
    <name>A0A1Y4DET3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57586">
        <property type="protein sequence ID" value="OUO57586"/>
        <property type="gene ID" value="B5F75_02085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013119388" evidence="2">
        <location>
            <begin position="22"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="27230" checksum="D79D021E79CE792A" modified="2017-08-30" version="1">MKRSLFILATLAMSSALYAQAETGNYTREKVLEIFSQYNPAVLENARQNADYNAILESFLAAYTSPQTEQNRYELIAVARNFDNSIRLQYATSVYEEAFVFSRMSGANLAPAALRFRKELFPLFENIWAVTVQLREYELQEVQAQLKALRKDKTLSDEERAEKENALRSRQAALQRESAALQENIGEQIIASVDAYIAQADQSLSEQLQAVRAAQAQAEAEQPLQTPNLQIKTKNKKPVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET7</accession>
    <name>A0A1Y4DET7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57607">
        <property type="protein sequence ID" value="OUO57607"/>
        <property type="gene ID" value="B5F75_02200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="168" mass="18708" checksum="E2491FC8FD0EB113" modified="2017-08-30" version="1">MGKGFTLIELLVVVLIIGILAAVALPQYEKSVEKSRAAEAVQMLRYMNQQKQLFILANGADAVYGKKNEDLGIELPAGLTCSWTGEEEVCCNKDWCYINTGFSWGSRCPVTENVIAARMEGDGREFDGNNLERKYLLEYETCEGSANTIVCYESDKWCKLFKGKGNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV2</accession>
    <name>A0A1Y4DEV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56249">
        <property type="protein sequence ID" value="OUO56249"/>
        <property type="gene ID" value="B5F75_06420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="6"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="272" mass="30192" checksum="3209EC50DAA7C870" modified="2017-08-30" version="1">MNTTPYAGFWRRAIAFVLDSVLAALPAAILCLPLLLWQATQVQPGNLDGHFIAVVLIYFAWQALAVVCLWLYFAGFESSAKQATWGKRLMKIKVVGKQGQRISFARASGRFFAKILSYVTLYVGFFMAGLTNRKRALHDYVAETYVVRQDFQPEDALPDTPSHPWWLGFIIVVFALFFAFMLVLGIAAEQPGARANQVAFQLQTLAENDALDYGSLEAGDIVFSHFTGGYRAVFTDNDGQEYSLFLPQAGETVCCESYPGVNCADIGFDECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEX6</accession>
    <name>A0A1Y4DEX6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="7" type="ORF">B5F75_02550</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57674">
        <property type="protein sequence ID" value="OUO57674"/>
        <property type="gene ID" value="B5F75_02550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="44"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="383"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="643" mass="69370" checksum="45508799A9C89634" modified="2017-08-30" version="1">MEMLEEQNQYVSLANKYRPQKFEDMVGQESISKTLQNALKLGRIAHAYLFYGPRGCGKTTTARILAKALNCTGHGNNKPTPEPCGQCPQCLEIAQSADMDVLELDAASNTQVEKVREAIIDTVALASSRDRFKVFILDEVHMLSTSSFNALLKTIEEPPAHVVFILATTEKHKVPATIVSRCQTFRFRPLTVEEISTHLLDLAGAENIDLTPGAAKIIAKNAGGAMRDALTLLDRAIAYSGERIDEKAVGEMLGLTPDELIKQAVDALVQKNGPQLHRVFETLKEEGFDANAFLKDLKNTLGDLFYFSLGQGEEPFAGAKETVKNVSSGFLAQLSRKINKIIEEVKFSDNALVSAEVGMFTVMDSCLDIESFIRRLEALERGEPASSGPASPARPPLSHAPAQATPAARTAKPSVQKAVPVSPKPAVAAKPAVNTQEDILADDEEEEDASLSPAAAASLQKTLSNRQIWDKMLQQFAKSPFVYDVMTNCSVTFSDAQWTLHFAPGKEFYQIPAQNKLPELEQAAQKISGRVIRIQLGTPEQPSAAQTAPRTESVKKPSAQAAKQPAKAAPCQEPAPVRGTAPHAAETASQKQSAPAGSSRAVISEEEPFVKGNFEADAAAGAAADTPEEVKDILEIFPGELMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF00</accession>
    <name>A0A1Y4DF00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57495">
        <property type="protein sequence ID" value="OUO57495"/>
        <property type="gene ID" value="B5F75_01610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="77" mass="8950" checksum="5510B9D3D44A1776" modified="2017-08-30" version="1">MRCTRLSSRAPQRQARRVIIIAFIRLISLPENSRFPVRLKGLFRPVCRMLCSDLTRRAIPANALSARKVQRFSQKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF10</accession>
    <name>A0A1Y4DF10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylosuccinate synthetase</fullName>
            <shortName evidence="7">AMPSase</shortName>
            <shortName evidence="7">AdSS</shortName>
            <ecNumber evidence="7">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purA</name>
        <name evidence="8" type="ORF">B5F75_01660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57505">
        <property type="protein sequence ID" value="OUO57505"/>
        <property type="gene ID" value="B5F75_01660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="39"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7">
        <location>
            <begin position="65"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="278"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="38"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="310"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="365" mass="40417" checksum="9055B05E0916EC79" modified="2017-08-30" version="1">MRQPVPNYRRCARKTIWAAHANLRRKSMIDIVCGGQAGDEGKGKISAYLSYKGNYDYCVRVGGPNAGHTVVKDGKSYTLKNIPSGFLNPKTKLVLGAGAYTKTEWLLEEVKLTGTRDRLIIDPYAVLISDEQTAAEKNASHFMQHIGSVGTGLGQAVRDRIERRDIKFAKDEPLLKDFIQDVPELLNGCLDKGGEILLEGTQGIKLSLLHGEYPFVTSRDTTASTFLGEAGLGPKSVRDVYVVFKPYITRVGPGPLERELTDEKQLEVYHTKGHEVGSVSKRLRRIGAFESRSAARAIMINNCTKIAITHIDMFPGNDRVKKYEDFSSEAKTFLDNLKALCARTYPHPEIALISTGPDMEDTLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF50</accession>
    <name>A0A1Y4DF50_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57555">
        <property type="protein sequence ID" value="OUO57555"/>
        <property type="gene ID" value="B5F75_01925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="102" mass="12167" checksum="12DE605F1410BF58" modified="2017-08-30" version="1">MSIFEALMMLGFGLAWPFNISRSLHTKTAAGKSFLFMITIELAYICGMIHKILYNFDLVFWLYVLNFVMVLIDLVLMIRYTKLDWFRKQHAQLREARRKARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF68</accession>
    <name>A0A1Y4DF68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">B5F75_06860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56329">
        <property type="protein sequence ID" value="OUO56329"/>
        <property type="gene ID" value="B5F75_06860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="88"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="124" mass="14158" checksum="57FD65668C05B203" modified="2017-08-30" version="1">MARVAGIDLPKNKRIDVALEYIYGIGKKNAKEVLAKLNGQIDPATRVKDLTEQQAGLLNTILQKEYKVEGELRREVAQNIHRAIEIGSYRGQRHRRNLPVRGQRTKTNSRTRRGRRKTVGSKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF89</accession>
    <name>A0A1Y4DF89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">B5F75_06915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56339">
        <property type="protein sequence ID" value="OUO56339"/>
        <property type="gene ID" value="B5F75_06915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="40"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="100"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="22152" checksum="024DD25E60DB8BC8" modified="2017-08-30" version="1">MTKKETKNVTKAPEGYQPRLQVLYKEKVLPALLKEMGVKSPMAAPKLTKIVINIGVKEAREDIKAMEVAKDDLTAIAGQAAQVRRAKKSISNFKLREGMPIGVRVTLRGAKMYEFMERFITIACPRIRDFQGFNPSFDGKGNLNLGIKEHYIFPEIDVEKSPKAHGMNITFVTTAKNDESGRLLMDYMGMPFRKASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFD3</accession>
    <name>A0A1Y4DFD3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_00840</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57352">
        <property type="protein sequence ID" value="OUO57352"/>
        <property type="gene ID" value="B5F75_00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="482" mass="53733" checksum="170BFAFCA0C018C3" modified="2017-08-30" version="1">MEQTAVKTKQPTGLWLLFMTELWERFSYYAMRSILILYMVYLLGMDKSGASNVYGTFTSLVYLSTLLGGFLADRYLGQKWATIWGGLMIAGGMFIMSVPTVAFLYIAMGLIILGNGFFKPNVVAIVGQLYEKNDARRDGGFTIFYMSVNIGAFFGPLLVGHLAAGGNYKAAFWIAGAGMVIGLFTFILGYKKFLLGKGAAPKDKPTFYKDPALWAIVLAIPMVVLYMQGHHTASYISFAVLAAAYYMYNKKVNRVKTENTAPLTRQEKQQIAVIGILAFFSIFFWAAFEQAGAALNLFAYEYTDRVISFFGHSWEIPANWFQSLNPLYVVIFAPLFSKLWIELAKKGIEPSTPAKFMVSLWLIALAFGVMLLGAFALVGNAKISLFYLAFTYLFQTFAELCISPVGKSMVTKLAPARFVSLLIGVWYLSNAVANKLAGVYSGYFQRISNEQFFLWLVIVPLAVSGLLLVFLKPIKKWMHGVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFR3</accession>
    <name>A0A1Y4DFR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_01645</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57502">
        <property type="protein sequence ID" value="OUO57502"/>
        <property type="gene ID" value="B5F75_01645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="288"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="432" mass="47585" checksum="FBC3A9C9402A118B" modified="2017-08-30" version="1">MTILIILLMLVLNALLAAYEMALASISRTKLSILAQEKRLGAEQALFMKDHMEGSLAVVQIGITLVGAIAAAAGGAGADEMFSPILQEWLSLPKRLADVVSVAVVVVPLSFITIVFAELTPKTFAIKNKEFVTLKFSPVMRVLYSILSPIVHIMEALVRFFTQKPLSSKKPDPKEAQQAAMTDLRTAAAIASSSRLFGKTEEKIVLSSAMFCIRKIREIQVPLDQVYMLDAGDSIADTFVKAHLDMHTRFPVRENPQDPQSIIGYLNFKDIFLSTKMASGSPTSARSIMRPILRLEADTLISAALEKLMKNKQHICLVTEGEKITGILTLEDIFEEMVGEIEDEYDFFPAYIRPIGSSLVASASAKMTDVFAQLQVSAPEGLAATTTVLQWTEQKLGRALDKNDKLKADGILVDPRKFRRHKLMEVLISKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFS8</accession>
    <name>A0A1Y4DFS8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Nitrogen fixation protein NifU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57522">
        <property type="protein sequence ID" value="OUO57522"/>
        <property type="gene ID" value="B5F75_01750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016217">
        <property type="entry name" value="N_fixation_NifU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010238">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000375">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02000">
        <property type="entry name" value="NifU_proper"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="7">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="NifU" evidence="5">
        <location>
            <begin position="214"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="282" mass="30290" checksum="3C0960746B04ACF7" modified="2017-08-30" version="1">MWDYTDKVMDHFRHPRNVGAIPNADGTGQVGSLVCGDALKLTIKVNKETDVIEDAKFETFGCASAIASSSILTEMIKGKTIAEASKITNQDIADALGTLPAEKMHCSVMGMEALEAAVKSYRQGGAPVVFEQQEEKIVCHCFNVSEETIIKAIRANHLKTVEDVTHFTKAGGGCGRCKGEIQKILDKVNGAETPAASAQKTFAQMTVVEKIKTIEHVLEEDVRPKLNMDGGSAELVDLDGNVVKIRLTGMCSGCAGAMGTLKNFIEKTLKEKVDASLTVEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG17</accession>
    <name>A0A1Y4DG17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56599">
        <property type="protein sequence ID" value="OUO56599"/>
        <property type="gene ID" value="B5F75_05250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="19945" checksum="4C8D04A310754677" modified="2017-08-30" version="1">MLKYYAYKLLRGLRLISQETYEKKAQKYGFKYSKDYKTIARSPLFDADWYLAHNPDVKAAGADPVQHYLTVGWQEGRPCTPYFDGKQYLEMYPDVAQAHMNPLLHWERYGQFEDRYAEIKGNKKAGRNKRKISIREKIKELWRYPIELQNEVEQLQAEVKMLRQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG58</accession>
    <name>A0A1Y4DG58_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000008">
        <property type="protein sequence ID" value="OUO55948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55948">
        <property type="protein sequence ID" value="OUO55948"/>
        <property type="gene ID" value="B5F75_07235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO55948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="332" mass="36596" checksum="CD5F746D04AB95BF" modified="2017-08-30" version="1" fragment="single">QQMNTLSWDGRDDQGRMVTPGTYMFTVESKDAMFPAVTNKASAVFPVDMYRVVDVSTTDVYGDSEAKATISYTLSKAMNVQVNIYNKDVVIPAYNSTTGDYADYTVEETHVAKGYTNNLGTVTVYEEGQTAPYATLTNVALGTVTTLTGNANPYTRDTVTVEENPNYVAGSAVAGEEQYVVTLKREQVTVTGNTRAPWPPHVCNHQSDAALFCDGEWSDRYQSCTGQQVDYVIPENVDESTACIYVNDTSFTNYPRTLAQAVTGALDVRLQPIKTFDRSATKVGEGMVITEEWDALYFYNPTPSSERHTQEEIAQCTGATDVKQCPYEMVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG91</accession>
    <name>A0A1Y4DG91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrolide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04470</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56679">
        <property type="protein sequence ID" value="OUO56679"/>
        <property type="gene ID" value="B5F75_04470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="225" mass="24831" checksum="5606075581D157DF" modified="2017-08-30" version="1">MIDTRDLYKIYTLGDVEVKALNGVSVSIEKGEFVAVMGPSGSGKSTFMNILGCLDKPTRGKYILDGIDVTATDLSELAGVRNRKIGFVFQGFNLIKRTTAVENVELPMIYNHTPAHLRREKAMAALTAVGLEKRAFHLPNQLSGGQQQRVAIARSLVCDAPIIFADEPTGNLDTKMSIEVMDLFTRLNKEMGKTIILITHEPDIAEYASRLIKFKDGEKISDEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGH4</accession>
    <name>A0A1Y4DGH4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rplA</name>
        <name evidence="10" type="ORF">B5F75_07040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56028">
        <property type="protein sequence ID" value="OUO56028"/>
        <property type="gene ID" value="B5F75_07040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="9" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="224" mass="23973" checksum="54062E1441259B9E" modified="2017-08-30" version="1">MGKRMQAAQKAYDKSKVYTLEEGAKIVKENAKAKFDETVEIHVKLGIDTKKADQQVRTTVALPHGTGKTKRIAVIAKGEHVQEAQAAGADRVGCEDIVDEVLKGKIDFDVLVATPDTMKDLAKAAKILGPRGLMPNPKSGTVTFDLANTIKALKAGRIEFKADAYGIVHAIIGKASFDAAKLVENAKAVMDTILRVKPSTSKGIYVQSISLSSTMGPGVFVTHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGT5</accession>
    <name>A0A1Y4DGT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56138">
        <property type="protein sequence ID" value="OUO56138"/>
        <property type="gene ID" value="B5F75_05825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PTHR10057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005859">
        <property type="entry name" value="PBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="157" mass="17475" checksum="75BD20249BD1CE45" modified="2017-08-30" version="1">MKYILEFFKLLFWLLLCQLPGLAGAAMVQPNLGWYHSLQMPPFMPPDAAFGMAWGVLYIVLGVAGFLAFRQGLKAARKPLILFIVQLALNALWTPVFFGSHNPAWAMVILLAMLAEGAWLACALRQKSRAAAWLMLPYGAWLIYAGYLNAGMWLLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGY3</accession>
    <name>A0A1Y4DGY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">proC</name>
        <name evidence="5" type="ORF">B5F75_06110</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56188">
        <property type="protein sequence ID" value="OUO56188"/>
        <property type="gene ID" value="B5F75_06110"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="3">
        <location>
            <begin position="2"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="4">
        <location>
            <begin position="156"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="263" mass="27070" checksum="87B1FE7D479508C1" modified="2017-08-30" version="1">MKLGFIGAGEMGGAIIRGLLKSGWPKADILVSVSSQASAARWREQYGLAAGTDNRQTAQQADVVLLAVKPGVVPQVLAEIQMLSPKPVVCMALGWTLEKLQAALPGWPVVRIMPNTPLALGEGVTLFAFGKWVGARQRQDIEAIFARLGQTVELAEQLFDAGTAVSGSGPAFVYAFIDALAQAGATQGLEAKQAAELAVQTVLGAAQMVKAEKIAPAQLAQKVATPGGCTAAGMEALQAAGLKEALQSAVAATVQKAQEAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH90</accession>
    <name>A0A1Y4DH90_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57049">
        <property type="protein sequence ID" value="OUO57049"/>
        <property type="gene ID" value="B5F75_04165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="507" mass="54601" checksum="AD695169DE934B83" modified="2017-08-30" version="1">MKEQNKQTQTENTVKQSSLAVLWGELKRLARSKKAWAVFILFFFLLLLTGLVPVSKIPFLRNLAWAMGYTPEETQEMSFLKALLSWNEHAKIARGELPDPTAAGVFGNDGGFATAHERMTAQKDSNLINLRAVNVALANQGKARDLIAGSFSGDDNKSPAARITGDSANTQANQTAPGEVFFGADASTLARDPKDGFNSVNSLKKIANPHIAGASQNDWLGRLVDKATRSDAGLQNLAKSLETGGTLSQLNPITEIGNHKAQRDMYYAWLTGMSARRTPNVVLKKTLASAGFDGADMPKKVFDSSGFSGIGINPDDVVADVDTIKLRLENEKECERAMSSSGETLTNQLQAAKAGINALAAAFPKTCEDVNGDFSNRLSVLRNQCEQIKLAYSDLSTFCGVAVKSGREGTCTTNNLQGRYDQYASYCAEEQEKCAALETPDEQKACLGEIKAAADYEEGDCYNGGCSESGVANLVKGTFNVGVNGEPVDPNAGDFFPETDWGSMNMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHL5</accession>
    <name>A0A1Y4DHL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56418">
        <property type="protein sequence ID" value="OUO56418"/>
        <property type="gene ID" value="B5F75_04280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="82" mass="9323" checksum="3B9303F171111B75" modified="2017-08-30" version="1" fragment="single">KGAALHEFERSERRVPRARTAGIFRQENDRKASPSLHMIYPGANPGFLLAPAQNDAGIFPFFFQNFQIAIIYLSFHFGENLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHV2</accession>
    <name>A0A1Y4DHV2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56518">
        <property type="protein sequence ID" value="OUO56518"/>
        <property type="gene ID" value="B5F75_04815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="117" mass="13787" checksum="BB3077EA1BB8F167" modified="2017-08-30" version="1">MPHTLKWFRPGRIIVVNDKMQQEYCYRLTALPGQRTEPRFTPQVSPAQMLAWGVFEGHYLNDCQEEFSAEWFARARQKLSPLRPDETKNCFGVKSRLPRGEWLKHGWILPFDPDPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHY8</accession>
    <name>A0A1Y4DHY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57279">
        <property type="protein sequence ID" value="OUO57279"/>
        <property type="gene ID" value="B5F75_00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="426" mass="49649" checksum="1AB5A081EB34DAA4" modified="2017-08-30" version="1">MKTYHTRRNTEPYQTMEYQNELHKNPHIEVLYSDPPQLRVNGEIIPWPQGKTPEEAYQDYLERESKSVPLNQLSEEELSPAEEQYFVRQQEYSLHPLRQQYLQDRLKQLDYLDRQQALQDDFTTRMYGKKDYSKEQKKIRQELQLGSTPQKRQAEKKFSWQDLQAGRRSQLPGTQSPAKRFWDIADEQTGQENYPNTPTAVSKEISRYKRENPNEYASYLKKWQDDQKSWQEIDQDIQDGTLSKQDISPAQWDTILSKSQKELDDKQDPQKNPEQKPYCNIYARNRLLQKGIYMAPDKNANQMIEDIDKKGSGWEKLPKKVDAQGNPTGKLDHQEAQRRAEAGGTVVATYHNPNNAEHGHIALVNAEAGMKRSGKWGGEVPSVDGYNPDTKQITEGGSLSEQFSTPREPHMDYYEYTGPEKEKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIU8</accession>
    <name>A0A1Y4DIU8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57599">
        <property type="protein sequence ID" value="OUO57599"/>
        <property type="gene ID" value="B5F75_02160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="86" mass="9912" checksum="58F9CB8BD94740F6" modified="2017-08-30" version="1">MQEKLKQLELLVSQVLARQKELQGENTALKAKLRSLEDGVEKLKAVESELKDVKEWKRNTQTALKRLAARLDKEIAKAQEEEKKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIW2</accession>
    <name>A0A1Y4DIW2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56878">
        <property type="protein sequence ID" value="OUO56878"/>
        <property type="gene ID" value="B5F75_03260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M10" evidence="2">
        <location>
            <begin position="267"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="687" mass="77457" checksum="E4B546CF4B48227B" modified="2017-08-30" version="1">MKRLLSILFVLFVSTGFSWGSAVWDDSSHEQLSAGNSSVLRLQKIRNYEFFLSNIIFPKQKKEVVVWASVNIPRLATANELTGYLENNPSYWRGVTEIAPYLEQAWKDWRDKANAWLPEKYYLPELKFTLKDIYKARMARNVHYNPKALNLTLEITTGKIGSDSVRGRAIPYFTDDGNGFGQIQFFMEEEWMGWLNSLNKSEEEQAIAAKEYKKAASAQLAGESYFSSPSSIGKDWDSYLSDDSKRFFNMLSKIPVAEWKSKGPWADYHQYVVTHEVGHLFGLVHINDKSSIMHPSIIGGQGVVRPSSEDGLRLATLVCWYHNQRAKKEVCVPLKHSKEEQEVRNRIQSLLKTWKEQPPVSPALAALKEMATPSTTTLPEIPGKPVTRQGFNQSASAETPVAVAVPVATTERTVAAAEESSTAEKAPSVLNQPVAQRTAARPAPLSGGLTPSTGFVQKIPVKTPTPPQLQPKSFAKRAPQAVEEGSPAGVAKAGAVPPVAEVKKPVKKCYICGKELEEGEYYSFSQSRHVHKNSLCAYRAFAQYHATDDASLARYEDFYFLHMPQDVVQARENLKNLGLTIKDVRRYAAQEAAAKKAQQEQIQAQFRETKQQEEARAKKQEKCGFYMVVTKDDLSRYAQENKEVLQQISKKEKGGRVLSKKERLVKQNYSQLYKNYELTQYCQEQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ59</accession>
    <name>A0A1Y4DJ59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rplX</name>
        <name evidence="4" type="ORF">B5F75_06920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56340">
        <property type="protein sequence ID" value="OUO56340"/>
        <property type="gene ID" value="B5F75_06920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="3">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="102" mass="10805" checksum="129E853E3AD3876D" modified="2017-08-30" version="1">MIIKKKDTVLVLAGKDKGKKGEVKSVNPAKNKVVVAGVNLVSKHTKPSQNKQGGIIQVEAALDASNVAVICGKCKKAMTPKVQVSADGKKVRVCRKCNEPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJC9</accession>
    <name>A0A1Y4DJC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57048">
        <property type="protein sequence ID" value="OUO57048"/>
        <property type="gene ID" value="B5F75_04160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="878"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1291" mass="140435" checksum="9B9105CCC9485A3D" modified="2017-08-30" version="1">MPEEKKKDSFTFSDKIKNSKPAAFKSFANRISSKIGSDGKPKKTLFERTKRDAPFFIAALVALLLLPFLYKYSGQVNEEPMITPGSEESIFDPERYGFDTVTGDPEGQIAQLAGRDPLSLIKGFGSDEEPADDSSLYDIDRSGLDDSSYTGTSVEENNTNIYRNTAAPATRAAFRRATTKINPLSNAGLTSRSGSKLGVGMWGGGLKTAAQRVAAEGPRNSPKPVSLQPLQAAGKPSRSYFGQGAAAEARRSKDAMSKANAMQALMDAQMRPIEPGKIGGLSGGSFGPGGGNGNLERRFAFNGKEPWWWDMMKRRSQMEWEARFNHKWDWIKFGVGLAQKFLDGFLSCIITGTDDWSMGKFLGAKAGAGSEAECAGLTEKEWNRSYPTIPFDKDNCRAHFRYGIEKDVQDPWEGSTSNEVSMGPIAQRMDCLSNGLGARLMAWWNRVAGKNVGTFPEAGDCNTFSKDGVYYADFSSTKDGWSVYHYVVGVPTAQLNAYYNLPPDEQEAALVVGYIGKGPEFNSNITAITQRSNFVPMFVESVAIKNKKIKKTELQEKSPEGYNYSGYWGLNKEGKAGAFKAKTYDEAIAKCRAMKWPVQQDCLNAINEQATDVDKAKKMVALVDGGSLPTYKAFMDTLREGGIIRDAVKVGTKQNLGISTKKAKEGKDWVTGARCPFPLVRISCDYLANISNNKGETQQSFPYAHLTFTNGMMGAQAYNAMKSRFLLSYTIQGENNTQPAAITTSTKTSDGGQWFYIPHQDVRPFQGAWSENITNAGFVTQSLGKERAKLPGAGDDYQVVATSSEIAALRNAGGRVVITWEVRQCDSLTTDGSSITKGGCQNGNIRALTADGKPGAALGADKPGNIVSTATCYYSDNSEPIGFETDIEEDPEDPPADDPEPDPEPDPEPEGTITLELADKMNGDFGISFRFAKERVALLQFPTMSVFARGGERSYKSALSTDNCTAVGSTRKSGQGSAKMMNQEEVKKYVDSVIAEVNASQEFTDAKTKFVHSGTVTVPQLVDAMTIAYSRNPQAQVPLNVVCALGKTIGYNSYDPQMIQEKEVWRNTFGAFAAYTGPNSSYFPALFAVDADGKKIVDRRFLGCGSAQEVKGTTVYAKKEVVPYHYGRYNWNHKRVGDRARYSTYAGSTGRDSYLKQITEGGWAKNGFNPSTYPLHAIADAVGFEQQISATDKELADFSTNATIDDINRQNYVRAYSRIFNDSDTSCGLEGNMPVAEALQYVGAVCVNGKNAKPSNGNFSACGGQYKRSSATGTPGGQVAGETVTESVTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJK6</accession>
    <name>A0A1Y4DJK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56510">
        <property type="protein sequence ID" value="OUO56510"/>
        <property type="gene ID" value="B5F75_04765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="437" mass="49475" checksum="4F5A32F91BE9D00D" modified="2017-08-30" version="1">MRQLLLVSIILLTFLSPVYAQLKPTRGLIKALTSTPAAAPSKTVSKALPKAAATSWGIEGMRSTDEMEALYCPPAAVQESFRCSPQAVILDKYDQMFNYGAPLVSAVEIPSPERALYIKQARAALMAPFPDITPTDHLVHYYKLSSALVGQYQDLYQQIYQFHLYILKRLKFSLASSAPQWTPTEKQEFDAELTQVDTAVQDMLAHMGGLDPALERIMTDIQWSRELISNMPGQFVLQDIKRTEPFNLNQYCLFSAPGMSPRHAIRNDDLFFNPALARQTAEQFCSQLPANLKVAVLNDSPRYTGQYENWTQEGVFTNGLTVSTFLSVNDFLRVHRQQPFDIILTDYFIPGGGGNLLVKLLRSERDFTPVILHSYAGEGHNAWEITRPKESLQKEYNLGYDAFLPTNDDFFSSRGYLYILEGLRNFYAAQKLRPQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK68</accession>
    <name>A0A1Y4DK68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00695</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57328">
        <property type="protein sequence ID" value="OUO57328"/>
        <property type="gene ID" value="B5F75_00695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023821">
        <property type="entry name" value="rSAM_TatD-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04038">
        <property type="entry name" value="tatD_link_rSAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="70"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="267" mass="29938" checksum="2213C99746561FCD" modified="2017-08-30" version="1">MPVFKTSALNHSATSPCFYFINFGAGLSAFLPGRWRCASVQIAIIQKEVFMKTENRPKVVYRFGEGVYLNITNRCPNLCAFCIKTKWHMDFHGNNLNLQGREPSASEVVAALDEELKKAPFKEVVFCGYGEPTMRLDVLLFVAQTLKGWMAQAKYPPFKIRLNTNGLGNLINHKDTVPELRRVVDVVNVSLNAENETVWRRIVRPEEGYENGYEAVRAFIRSCVAAGFDKVVASCVDQTGADPKAVQKIAEADGAQFYLRSFLDAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKF3</accession>
    <name>A0A1Y4DKF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57408">
        <property type="protein sequence ID" value="OUO57408"/>
        <property type="gene ID" value="B5F75_01140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="364" mass="41495" checksum="7954D9B867085AF4" modified="2017-08-30" version="1">MRVSIFTKYIAKSLLTFFIGVLGVLTFVIFMNQFIRILDMAMTYGTSFGWIVSSLLNVLPNVFCLSAPMAFQIAILLTLTNMSEHGELIALRAAGFSFKEIIRPLFICALGLTVVMFVMQNWLTPRSYKRLLDRRSEARSKITKVNLEPKTFLNLGEWDLYLESLDKDTDVARQIHLIKKEDNGALSTKVNASSGKVILTHTAIGLQLKDGQMQRLDDKDPSSFIAANFDEYIMSISLLKAQYRRLRVGEMSTTKLLRRMRQMPLDPETINEYRTEISMRNVLAFSPIVLLFVSCPIGFSFGKRTNKGWGMLFSVIIIFTFYLLMTLGLSLGKKYGWIAYPGPWLPIIAGIFAARYLWKKRLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKN6</accession>
    <name>A0A1Y4DKN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56860">
        <property type="protein sequence ID" value="OUO56860"/>
        <property type="gene ID" value="B5F75_03165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038247">
        <property type="entry name" value="Jag_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032782">
        <property type="entry name" value="KhpB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14804">
        <property type="entry name" value="Jag_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01245">
        <property type="entry name" value="Jag_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="R3H" evidence="5">
        <location>
            <begin position="226"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="70"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="70"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="425" mass="47365" checksum="1549921451517705" modified="2017-08-30" version="1">MPSKIKVQAREVSEAIAKGLKELGLRRDQVEVTVLENPKKGFLGIGARPAVVELRQKRWSTADLDSQIYMDVPKKRSSKSSRGGRGRKDRSESRGGRRNSRKSEYTNTQPREAREKQPKANEPQLLPSEAIQNAVIPENLKAPMQEAKEYLEKVLTHMGVKVENLNVWWDEKQQRILLTFDCDHPAIVIGKEGKTLEAIQYLCTLALSRHFDKPISVITDTQNYWRKAEDKIDAEIAKGIDMIKRGNSVFRFRPMSAQLRRYIHRAVEGNEFVTTASEGEGKWRKVTLRPTEKALELAHAHTAPADFVPGVIGEDIPEQTPAQEAVAEAEKEKELNEYHESCSCCAGEAETPAQEAAQPAPVQAAQTPVQETVTVHETITVQETLTVTPVQQPAAEPAPKAEEKPACSCGPLFDAPAEQPKTENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKV6</accession>
    <name>A0A1Y4DKV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="17" type="ORF">B5F75_07195</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56051">
        <property type="protein sequence ID" value="OUO56051"/>
        <property type="gene ID" value="B5F75_07195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="14">
        <location>
            <begin position="20"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="13">
        <location>
            <begin position="146"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="13">
        <location>
            <begin position="302"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="15">
        <location>
            <begin position="489"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="16">
        <location>
            <begin position="567"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="11">
        <location>
            <begin position="693"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="12">
        <location>
            <begin position="1180"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1258"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="904"/>
            <end position="973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO56051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1287" mass="143744" checksum="BF6204923883D2B5" modified="2017-08-30" version="1">MIEKQTNFGKISTKLPLPDLLDMQKQSFVDFLQLDVPPAKRELKGLQAAFEDVFPIEAPDGSMKLEFLKYELGAPRYATPAEAAVRDSTYSAPLKALLRLQVKQKNGKMKEASEQDVTLCDLPLMTDAGCFVFNGAERVVVSQMHRSPGIIFEEDEEKKQSTFGKRLYVARIIPYRGAWIEFSFDLMNALWVRIDRKKKVLASTFLRACGLETNAQIIQTFYKCEDIEVKPSNIDGVIGRYAADDIYDPATGEVLWNLDEKAALPIDDKLFKTLIEKKVKTIKVISGKPRQDDPGILATLEHRKDSIRTAAEAQAEIYKKMRGQDFVVKEQAETFLNNLIFDNIRRYDLSFVGRYKINKKFANMFDLISKFKFKKFTTPSEKRRTLAPEDIIVTVKYLLALNAGEDAQKMYGDGFTFKVDDIDHLGNRRVRGIGELLENQIRVGLSQMAKTARDRMNRELTNPTPRALVNAQPVQAIVRKFFGTSQLSQFMDQINPLGELTHKRRLSALGPGGLNRKRAGFEVRDVHYTHYGRVCPIETPEGPNIGLITSLACYSKVNKYGLIETPYRKVVNGKVTDQVEELTADAEDDKLVAQANTPTTKDGKIDTDLVACRVRSDYPLVSPKAVDYMDVSPLQVISVSAALIPFLEHDDANRALMGCNMQRQGVPLLMPEAPYVGTGIEHEVARDSGTSVVARRDGRVQFADASKIIVEAKDGTYDVYELLKYKRSNQDTCINQHPIVKTGDNVKARQVIADGPSMDNGYLALGRNMLVGFMCWEGYNYEDAILVSSRLVKDDVFTSIHLHEFTVDARNTKLGAEEITRDIPNIGAEALSHLDNDGIVLPATVVEPGDILVGKVTPKGEQQLTPEERLLKVIFGKKADDVVDASLRVPPGTSGKILGTRVFVRKEKLTKAEEKARLTALENEKDSTLELLKEQRKRALANAKASIKKEADLKKEEARINALYKLMEKKTVEHYEREMEFSKQGDELAVTVNKSVKVYIASKRKLHVGDKMSGRHGNKGVVARILPEEDMPFLPDGTPLDIVLSPLGIPSRMNVGQLLETMLGWAAHYLHYNAATPVFDGPSEAEVVEQVRKAKEKILDDKGLTGKAREEYAAKYLPDDYCRITLYDGRTGEPFEEKVTIGYMYMMKLIHLVEDKVHSRSTGPYSLITRQPLGGKAQFGGQRFGEMEVWAMEGYGATYTLQEFLTVKSDDFVGRTKMYESIVKGEAPAQPGVPESFKVLIKELQALGLSVDLLKKVEDGGQTPSASAEKKAEAKTEAPEETGAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL26</accession>
    <name>A0A1Y4DL26_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56121">
        <property type="protein sequence ID" value="OUO56121"/>
        <property type="gene ID" value="B5F75_05735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="265" mass="29355" checksum="764A65F331E368E4" modified="2017-08-30" version="1">MKKEFSVLKQCLQAAARAVRSRFGKVGYELKGKANLVTTADVASQKTILSILRKNFPDHDYLAEENGVKNTGSDYVWVIDPIDGTTNFAHTFPQCGVSIALFYKNEPVLGGVTNPATGEMFLAQKGKGATLNGKRIHVSKTPRLDQSLLVTGFPYNRFTRMPQLLRRFEKFLNSCHDVRRLGSAALDLCWLAAGRTDGYWEDNLNPWDVAAGVLILQEAGGKVTDFNGRKYKKIPDYGPTLLASNGKIHAQMLQIIRQTDMASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLA5</accession>
    <name>A0A1Y4DLA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56201">
        <property type="protein sequence ID" value="OUO56201"/>
        <property type="gene ID" value="B5F75_06175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="66" mass="7184" checksum="D359682DE6D49BC1" modified="2017-08-30" version="1">MMQSVNITIIGMLVVFVFLIIMVGIMKVLGKLVEAMEKYFPQTVPGAEDNALIAVAVAAARRFQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLD9</accession>
    <name>A0A1Y4DLD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_06330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56231">
        <property type="protein sequence ID" value="OUO56231"/>
        <property type="gene ID" value="B5F75_06330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010991129" evidence="5">
        <location>
            <begin position="20"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="341" mass="37813" checksum="666277E3090573C9" modified="2017-08-30" version="1">MKKVWLFLLALGLSAPLAAQEASADKLSPEEAAAVASILAKTAAQQAPEEDDKIVLPEETKKQAFDEVNPPKPAETSAAAEAQTPAQTEQTNTPVRPLDQEASSSPSDATANPPQTPGDPSATQEQEPPAKCLTVAYIDIDEAFNEHPRTIAVKEQIRLKILSKEEEVRGAKALIAALETENAQLARQVRELKPYYERIVVEPQPLLPKIEESADALQLGNLLNRLTFSGTEILSTSPLNTPAELDDLTARIASNKKIIAERSFFIDNYKYNTREEILQLEKTEVNEILKDIYTEIKSFAKKRNVGAIVRKDEVLYGERPVNVTKDFIDRLKKSKKYRKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLU1</accession>
    <name>A0A1Y4DLU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56361">
        <property type="protein sequence ID" value="OUO56361"/>
        <property type="gene ID" value="B5F75_06045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="3"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="298" mass="32750" checksum="8DD742EE57CDB62E" modified="2017-08-30" version="1">MLVVGSVAFDTIENANGSVQRVLGGAASYASICASYFASPAVVAVVGTDFTQQDRAPFVKRGVNLDGLEVRDGKTFHWGGSYDKDFNTAVTRFTDLNVFQNFNPVLNDIQKNARAVFLANIDPELQLSVLNQVKHPSLVACDTMNYWISSKKETLLKVVKRIDVFFLNEGEARQLTGEYNLIKAGRILLEQGVKYVVIKLGSNGAMLVSNKGLVQLPPFVLEHVHDTTGAGDTFGGGFTGYLASLEDWNNLTAIKRAMMIGNVMASFTIESFSVDRLANLSKQDVDQRLEEYVSMLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLU4</accession>
    <name>A0A1Y4DLU4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57270">
        <property type="protein sequence ID" value="OUO57270"/>
        <property type="gene ID" value="B5F75_00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="177" mass="19281" checksum="317F76874ED9017B" modified="2017-08-30" version="1">MQKKGFTLVEILVAVMIVSLLVTMAVPMYDKTVEKSRMAEARTLMKKILESKLRTLDNMDRENYANGLFGFENLDVTIPCVDASTGARLTRCTGNTLYTKDFKYTLLPQGSVSGSTATIINGVCAVRRKGDNAGVNFLYLGELETNSNRDNFLCNDGAGDGSCEVYGLDSTASGWCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMB8</accession>
    <name>A0A1Y4DMB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56541">
        <property type="protein sequence ID" value="OUO56541"/>
        <property type="gene ID" value="B5F75_04935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010181">
        <property type="entry name" value="CGCAxxGCC_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09719">
        <property type="entry name" value="C_GCAxxG_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="151" mass="16879" checksum="1ABA9DE4CEA7500E" modified="2017-08-30" version="1">MMKSRVQEAKNKHKQGYNCAQAVACTYCDLLGMDEKTAFRAVEAYGLGIAKRYETCGSVCAMMMLAGLKNSDANLQAPASKFSTFELGNKMIQKFEDWNTSSCCALLRGTDGKTDRLRSCRGCVADCARIVEDFLFPGQFEPYEERHPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMD4</accession>
    <name>A0A1Y4DMD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsA</name>
        <name evidence="8" type="ORF">B5F75_05040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56561">
        <property type="protein sequence ID" value="OUO56561"/>
        <property type="gene ID" value="B5F75_05040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="7"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="416" mass="44961" checksum="4F196ECC38D13315" modified="2017-08-30" version="1">MAKTNIIAGLDVGSGKLTCIAAAHDFETNTLKVLAGRSVPCKGLRGGMVSDIRETSAAVTHILGSIERECNQEIGNLFVGVRGAHLESFSNHGTYNISRMDKEITQADMDLAIENAKAMPIKNDNEIINVIPQGYAIDKQKGITNPEGMEGSLLEVDVHITTGSSTHLNNLAKAIQRPGYKIDGTFYSLVPLADTVLTQEEKEIGALILDLGGETMSVGIYIDGILKFSRDIPYGCDLITSDLSRLLHTSRQNAKEIKEKYGVSFPTFLDEEGEIPVPSLDGRSTHNIKKSFVLDIIQPRVEELIEQVALCVENSGYKKLPVVGVVTGGGSLMPGITEHCVNILGLKEARRGVVQRDLITSDDEFFDPLYSTAMALAIYASDNSGYDDYSGGSYEKGSSFFGKLGKLFKGVDIFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DME4</accession>
    <name>A0A1Y4DME4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative manganese efflux pump MntP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mntP</name>
        <name evidence="9" type="ORF">B5F75_01475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probably functions as a manganese efflux pump.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MntP (TC 9.B.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57470">
        <property type="protein sequence ID" value="OUO57470"/>
        <property type="gene ID" value="B5F75_01475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01521">
        <property type="entry name" value="MntP_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022929">
        <property type="entry name" value="Put_MntP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="20356" checksum="086F226FDF8AFF0F" modified="2017-08-30" version="1">MNILSSLLVALGLSMDNWAVTIASGCSHHDAIPKSYIFKVSSLFAAAHFVMFSGGWLCGAGLGKYIGAVDHWIAFAILVFIGFRMIQESRSREEAGQDVCVLHTFKMLCALAVATSLDALLVGMGLAFTEAPFWATVLMLTVCVFVTSWTGFYVGAYLGRKFGKIMEALGGAVLMFIGLKLLLEGVGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMJ6</accession>
    <name>A0A1Y4DMJ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">B5F75_05315</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56611">
        <property type="protein sequence ID" value="OUO56611"/>
        <property type="gene ID" value="B5F75_05315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO56611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="188" mass="20602" checksum="5CC8E8D6A722CFFB" modified="2017-08-30" version="1">MNKTTTTVLGIDPGLDRTGWAILTRDARSVLSLRACGLIHTDAHQELPNRLEYIFAELQKLIAAYGPDQVAMEQNFFLKRAVTMANTVMTRGVIILACQLAGKPISFYPPKRVKMMLCGTGTADKKQVQRMVQLTLNLDKAPSPDDVADAAAIAVCHAKTAPLNAMINVKAAFLEKLKAAKQLQLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMM1</accession>
    <name>A0A1Y4DMM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57550">
        <property type="protein sequence ID" value="OUO57550"/>
        <property type="gene ID" value="B5F75_01895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="161"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="339" mass="39075" checksum="C63ADFFA5AED8425" modified="2017-08-30" version="1">MKHVKEIEKGKVYLIDFRDSEGKRWRKKIHGTKKYAVEVATRLMKEKEDDVFFPERRTLKVTYGQLADAYWELHGKELPGRSAKSMWKICKDKFGNVKMKDLTSTKLQQFYNELLTKGGIKNKGLKSSTCNRYFAVLGAVIEYGIKHDLWNGKNPCVVVTKKPEDNNREAYWGNDKLTQLFQYCKNKQAQQIVRFALHSGMRRREIFDLDWSNVDMGLGVIYILQSKTHQKRIVPMSEHLKALLQEIGPKTSGKVFTMKVSTFESAFKRAKAKAGLKGLTFHDLRHTFATTFRVRNGSMSNLQGILGHTTPRMTNRYAHLSPEYLKEVIACMNTPQGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMP5</accession>
    <name>A0A1Y4DMP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56671">
        <property type="protein sequence ID" value="OUO56671"/>
        <property type="gene ID" value="B5F75_05625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="14410" checksum="EE105B5E11D51142" modified="2017-08-30" version="1">MAEQNNVSPEQVAQALMQAMGQVNGMMGGQAAPAVQAGNTMLPAMPAQPVQMGGVPNPTGWSVPVETEINGMTVTVYVQFPAQTFPQFQQIIAAMLNMGYQVRGFQRNGGGYGGNGGSYGRGGYGGGYNRGGGYGRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMR7</accession>
    <name>A0A1Y4DMR7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prs</name>
        <name evidence="8" type="ORF">B5F75_02215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57610">
        <property type="protein sequence ID" value="OUO57610"/>
        <property type="gene ID" value="B5F75_02215"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="227"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="314" mass="34821" checksum="096FE8D97124F968" modified="2017-08-30" version="1">MTKSVNGDLRIFSGNANIALAQKICSHLNMEMGKLRVERFADGEIDVQILESVRAHDCYLIQPTCPPVNENLMELLIMIDAFKRASAGKITAVIPYFGYARADRKASPRVPITAKLASNLITEAGADRIMTVDLHAGQIQGFFDIPVDHLRARKVFLDYFKDFDRKDLVVISPDVGGVERARKFAARMDAGLVIIDKRRPKANEAVVYNVIGDVKDKVAIIFDDIVDTAGTLTTVAQKIKERGAREIYAVCTHGLLSRNAIDKINRSEIKKLVISDSLPIRDLGPKVEVLSVSYLLADAIKRNHDGRSISDMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN06</accession>
    <name>A0A1Y4DN06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57700">
        <property type="protein sequence ID" value="OUO57700"/>
        <property type="gene ID" value="B5F75_02690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="541"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="868"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="898"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="924"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="972"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1060" mass="117032" checksum="084FE43CD063C441" modified="2017-08-30" version="1">MQEKEQQATRQTEQKKGFSSFFIRRPVLTIMCSLALVILGLMAYNSMGVGLYPNMDVPYVLVQTTLSGASSEEMETSVSKVIEESVNQIEGIDELNSQSTEGISLVVIKFDMDKDQDVAAQEVRDKVDLITNDLPDGTDAPVIMKLDADAISILNVVVSGDRDIIELTEIAKKKVKENIENTRGVGSVSIVGGREREIHVIVNPFKLYSLGLPITAVKSALQDQNVETPGGRVEQQHQEYTLRVLGRIDNVPAFNDIFVARKNGTSIKISDIGYAEDSGEYDRESTFLNGRRAVTLEVKKQSGTNTLAVIQGVKDKLDQIKSTLPKDIKISLMMDQSGTIQASVNTVLEHLILGGILAGIMVLIFMGSLRSTFIAFLAMPISIIGSFLFMNMMGFTIDSMTLLGLTVAVGIVIDDAIVMLENIFRHMEKYNKTPLQAALDGSREITSTVIATTLSILVIFLPLAYMSGIVGRVVSSYGMTVVFAIALSGIVALTLTPMLCAKMLKQGEKKTKLDHIVDAINQKLVNIYIPMLNWSIHHRKTMVLISVLCLFALVPMLKIVGGEFFPQEDSGKIQINVEAPVGTSYTDTQQILMQLEQDVRRMPYVKDVLISAGVGSSFLDSNPSNQGHVRFELEDRKTRHGITTAKYLELTREMMKKYDGLKTSSYIVSDGPGGLKDVEYRISGPDINKLTEYGNAVLDKLRQDPRFIDLDLSLDLAKPEYRVIINREKAHDMGVNVTDIASALRTMVGGEDEVTKYKEGDELYEVRIRVGEEYRDTKEAVSALMVPATIDGKETIVRLDSVATIEEGTGPSQIDRYNRQREITVEANLNGLDTRTAMGIIQQAYDSLDVSNEYSGGTSGSAKEMGRMFQSFILAFVLAFLFKYMILAAQFENYSHPVAIIVSLPLTVPFAVFSLLVTGQTLNIYSLLGLFMLIGVVSKNAILQTDYTDQLRARGYGRTDAILQANRVRLRPILMTTLTLVVGVVPMLISNGEGAESRRSLAIVIVGGQALSLLVTLLMTPVTYILMDEFGDWINYKFRGIPYPEDKSKDTILPEVPQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPI4</accession>
    <name>A0A1Y4DPI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ORF">B5F75_00540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57301">
        <property type="protein sequence ID" value="OUO57301"/>
        <property type="gene ID" value="B5F75_00540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="210" mass="22757" checksum="F33B5D7A20B8666E" modified="2017-08-30" version="1">MITTVTILVLFSYLLGSVPTGYLIAKRSMGIDIREYGSGNPGAANVYRTVGKWAGIATFLIDGLKGFIPVCLARHYCPENYWVAIACGVIAILGHMWTIYLKFRGGKGVATSAGVFAALLPIPTAIAFASFVVCVALWGRISIGSICACVVLPIASFFIGNHPLSVNLMVTAVSLLVIYKHIPNIKRLLAQKELKFEDGAKKRKEQHENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPV6</accession>
    <name>A0A1Y4DPV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57391">
        <property type="protein sequence ID" value="OUO57391"/>
        <property type="gene ID" value="B5F75_01050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="10"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="2">
        <location>
            <begin position="264"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="456" mass="52389" checksum="4EBFE4F0E73CAFAB" modified="2017-08-30" version="1">MDPRLDILPNKPGVYIMRSKEGTIIYVGKAKNLSDRVKQYFQESNLYSRGWKLPCLLPLIAKIDYVTTASERDALVLEEKLIKQYQPFFNSLGKDGKSYPYLKLTMGEDYPRLQLTRRVVRGKDLYFGPYPKSSIVKSLMRFLWKSKYAPLRPCKWNFSRQKPLDERKINTCIYYHTGQCPAPCAGKISYEDYRAIAQRMAEFLDGHFGNITETITSLMHQHAQKLEYEQAAVYRNFLQALAHMQERVIVGRFKDDQITTAMENTDKLKRLAQVIGMHKLPAHIEAFDNSHLFGREAVGCMVCYINGEKNHEHYRRFKIRSKLPERGGSDFAMMEESVYRRLRQLKRDPSQTPDLILLDGGKSQISAAMNAFDRAGLYIPFIALAETHEGIYLPGAAESIKLPIGDPALNLLMEIRDEVHRFAITYHRKLRGKAELTGHQSQEGLIDGKDPAGRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPX4</accession>
    <name>A0A1Y4DPX4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57421">
        <property type="protein sequence ID" value="OUO57421"/>
        <property type="gene ID" value="B5F75_01215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825069" evidence="2">
        <location>
            <begin position="23"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="484" mass="53777" checksum="95B90BCD4C00DA67" modified="2017-08-30" version="1">MSIGKYLVFCLVAASTATSALAQGVGGSAAKMIEKSVTASKLLQQNSSAAFLRETTLKNYFSSLEEFRHALRSNPAWALSPAAASSRKQLQAMGLSLPALPPASADVAAKEKYLQALSDILYREAKALGQIVQANPIPAFRTPHLKTLVEAAKTNGERSLLKPFTVPAPDTFFAAGDPDFSLQVSGVGQVRITPFIPSEDRGSSLYIDPVEYGFFCSHLLAGPQQALDQIAKNDRLPQKQKELMLSVMKNTFSLLDFNFVRKYIIAFNRLPLVETPANTEMEKLYQAQGYAAAQEKRLLQKLKSAGRWTPQDYEAFISWSVYLDPQQAQLLLKAITYLEPDAALLVLAHPLESSLVKKIEGQITHLQNNRHLIWPNGIILSKMPLLQTPQNMQAAWKKELTEYLDILQTRLSKLAQERDFLQRTHQRVSVNALGILGDEPENAAIQTAMQLEISALLARLDPLIEQIQKRIYQIGTELEGMERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQM1</accession>
    <name>A0A1Y4DQM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Deoxyhypusine synthase-like protein</fullName>
            <ecNumber evidence="3">2.5.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.-.-" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57671">
        <property type="protein sequence ID" value="OUO57671"/>
        <property type="gene ID" value="B5F75_02535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00640">
        <property type="entry name" value="DHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023496">
        <property type="entry name" value="Deoxyhypusine_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="358" mass="39773" checksum="84C5331830DABCF5" modified="2017-08-30" version="1">MAKLTKKDFLKDTIKHIDLKKYNVVPMVEAFGSMAYASREVARASKIYNMMLSDKKCSVILCIAGSLVSAGLKKVVVDMIQNNMVDAIVSNGANIVDQDFFEALGYKHYIGTPYNADDNLLRDLHIDRIYDTYIDEDQLKECDETVHKICNSLEPRPYSSREFIWEMGKWLEKKGKGKDSIVYNAYKYGVPVFVPAFSDCSAGFGFVAHQTEHPEAHVSIDSAKDFLELTKIKIKAKETGLMMFSGGVPKNFAQDTVVAAEILGADAPMHKYAVQITVADVRDGALSGSTLKEASSWGKVSTALEQMVYGECTTLIPLIIGYGYHKGAWKKRKAANYVKFLQDEDAKVAALKAKKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQM9</accession>
    <name>A0A1Y4DQM9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_02590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57681">
        <property type="protein sequence ID" value="OUO57681"/>
        <property type="gene ID" value="B5F75_02590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="447" mass="49267" checksum="0508BE4330C8229D" modified="2017-08-30" version="1">MTKNPWYYIPSLYLAEGFPYIIINTVSTVLYADLGFSNEKIAFWTGWLYLPWILKMFWSPWIDARSTKRRWLLGAQTALAGVFLLLAALTAWEAFSFAAHQGSLTFFYLSLFGLLAGAFASATLDIATDGYYLLALTPVQQSQFVGIRTIFYRLAMILGSGLLVAGVGALSQAGAAGQQPLVPWPFNWALLFLFLAALFAAAAGWHRFILPKPAEDRPVHAARGNAWGDSFKTYFTQKNILYILAFILLYRLGDAFLEKIVPLFLLKPQAEGALGLSVQTYGLIKGTLGLGAVVVGNLAGGWLLGKYGFKKCIWPFAVILILPNFFYAYMAWAHPSTGLITVLITLEHLGNGLALMAFTVFIMYISQGAYKTSHYAISTGIMALGMMLPSMASGWLQARLGYTGFFWLASLVSLVTVAVVPLSFKIKSIEETEASFRTHKHSLEDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9X0</accession>
    <name>A0A1Y4D9X0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sodium:alanine symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_07130</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56044">
        <property type="protein sequence ID" value="OUO56044"/>
        <property type="gene ID" value="B5F75_07130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="466" mass="50351" checksum="EA91717D595C09D4" modified="2017-08-30" version="1">MSDILTQAITLLNDRFLGYVLMAALLFAGLYFTIATRFVQFVRPKEMLRLMLGQTGNPKEKGHISSFQAFSISTASRVGTGNIAGVAIAITVGGPGAVFWMWLIAVIGAASAFAESTLAQVYKVKSGAHFRGGPAYYMQNALGSRKMGLAFSIIITLTFAFVFNSVQSNTIAQSLQTTFSLDPFLTGIILAGLTAVIIFGGLKRIAKFSAVIVPIFALGYIAITALVVLFNLEKLPGVLALIVSDAFSLRNVAGGALGATIMTGARRGLFSNEAGMGSAPNAAATANISHPVKQGYVQAFSVFVDTLVICSCTAFIVMLADYQSFPGLEGIALTQKALTQELGPVGNYFISASVLLFAFTSIIGNYYYGQANVEFLTRRRWVMAFFRTGVSVMVLLGAILQLKLVWNMADLFMTVMALMNIYAILRLRRQVIDVLADYRRQKQAGKDPQFNPENVPSVHHADAWTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAB7</accession>
    <name>A0A1Y4DAB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MurNAc-LAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56174">
        <property type="protein sequence ID" value="OUO56174"/>
        <property type="gene ID" value="B5F75_06030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="1">
        <location>
            <begin position="505"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="646" mass="72740" checksum="11418266B3C77C94" modified="2017-08-30" version="1">MTSSQLTIELCYHFIRMKRILFLLFSLFVFEAAVHPQNIPTAPYLPAQGRSSAPNDSITVQFPYEKMTVTRGAARIFLFGQIHLSGPVKLDINGESVPVQENGTFIAFLPVKSGEFEFLLTASNGRETVQAVRRIVVPGVDIKDFSSRAEFDPEEIFPQSPAELLPGDVVGLYVRGTPGAEVTFTLSGLKDAKNIPMKEDVSSPGMYRAKYLIREDQKPKTAKITYNMENGPDGSKAKITAPARLKVLDAKDPFTRAQVLSAGVKLRKIPTPRENLYPFYRAYGEVLLNGRMNGQYRIALNENESAWLEEKNLKTLLFSGYTPNRITELKTTALPDKTRLSFAGSRIIPISVHEFNDRMELTLYYTDGFDENYSFDTTSPIIESITWSQPARDTLLFKIYFKKDSPLWGHAYDFEGNNLIIDLMHRPGLTPTKDKPLQGARILLDAGHSPRRTVPYDGAVGPSGYLEYEANLALAEDLKPLLEKAGATVIMTRHGNNRMSLQNRYQLALKEKAHIFVSLHYNALPETVNPLARARGFSVYYNYPHSFKLAQSVYDAFTRHVPLPDNGMIANDVLFIPRIPQLPSILVENAYLILPEQEQMAKTADGRSAFVQALYEGILDFYGVKPRPEKKPLRRNAFKKPGRRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAW4</accession>
    <name>A0A1Y4DAW4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">B5F75_06935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56343">
        <property type="protein sequence ID" value="OUO56343"/>
        <property type="gene ID" value="B5F75_06935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="67" mass="7732" checksum="D8737CCCE0582589" modified="2017-08-30" version="1">MKTNEKEALKNKTLAELNEALGKAQEKKFNLLFKHSTTPIANPMEIRAVRREIALLQTLINQKKEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAX3</accession>
    <name>A0A1Y4DAX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56206">
        <property type="protein sequence ID" value="OUO56206"/>
        <property type="gene ID" value="B5F75_06200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="26" mass="2985" checksum="8CBF67C9E199B0C4" modified="2017-08-30" version="1">MMKNIYSFFPLGKHSGFTLIELLVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB89</accession>
    <name>A0A1Y4DB89_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AA_kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56115">
        <property type="protein sequence ID" value="OUO56115"/>
        <property type="gene ID" value="B5F75_05705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_kinase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="242" mass="26080" checksum="8F140A60CB5F23FD" modified="2017-08-30" version="1">MRKVCIMKFGGNTLANKQKLLMAANLIKSRYDQNFIPLVVASANGNLTDVLLDHAFSITPTPDKRELDMLVTTGERVSVALLSIALRAIGVPSISLTGSQIGLITTCTHTGADILELKGTRLVNEIQKGHVPVVAGFQGIGQDKEITTLKRGGSDVSAVFLAAQLGADHVEMIKDVDGVYSADPNKDLKAQKYEVLDFDEMYKLALNGASVLHPDAVRLAKEKGVEIRIVHYQTGQTGTVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBH3</accession>
    <name>A0A1Y4DBH3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="5">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_04680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56493">
        <property type="protein sequence ID" value="OUO56493"/>
        <property type="gene ID" value="B5F75_04680"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="116" mass="13472" checksum="65F6A27724A1633F" modified="2017-08-30" version="1">MSKVYLTQCGSFTARHGHGGTLAEEVHTHTFHYEVTFFGPTNAEGYLIDFRQLADTFKKELESRLEGSDLGTFLPQPTTEALCVWMYKRLKERLPHLYSVKVAEEPDRWIEYRGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBH9</accession>
    <name>A0A1Y4DBH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56426">
        <property type="protein sequence ID" value="OUO56426"/>
        <property type="gene ID" value="B5F75_04320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011563" evidence="1">
        <location>
            <begin position="19"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="154" mass="16979" checksum="9C9B8773543BBACA" modified="2017-08-30" version="1">MKKLWLLFTAAVLLTACASVDETENLANCKFALRSVELTNYNLTSFDFDVIIAITNMNRKQAASLKRFEGELTVNEDKMADVTLDEMKIEPNATKNAKAQLNVPMTAFNSKLLGLISMGSATLDYHLTGTMYFEGPLGTEIPVPVDIGRMGSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL2</accession>
    <name>A0A1Y4DBL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56543">
        <property type="protein sequence ID" value="OUO56543"/>
        <property type="gene ID" value="B5F75_04945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012734562" evidence="1">
        <location>
            <begin position="23"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="255" mass="27427" checksum="B297C76A1AC2836D" modified="2017-08-30" version="1">MNIKGIWAALAVVLLGVSGASARNIWDDFSANVTRDNVRAFTKDLGGLIGSGTYTTGRILGWGGFQIGPRGSMVFRMSQGNGADYATKQHTALGDRDEVGEVFYPWLQADIGMPFRIDGFIRASSYQGLTIAGGGLRWGITRPSEVLGSFQPMLVVAAHSASARDFSATHYNASLVLSMKFKYFVPYIGGGVDYTTLNINQAQLDATLEGESEHAATARATVGFNFKLPSYMDLSLAANYAYYGLGAEASLTLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN0</accession>
    <name>A0A1Y4DBN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56547">
        <property type="protein sequence ID" value="OUO56547"/>
        <property type="gene ID" value="B5F75_04965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="10"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="142"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="354" mass="39183" checksum="F5234EF6E53E47DE" modified="2017-08-30" version="1">MAIKSLASQRMADFRRVLKQAGLDGYLTAAHLEQRYLSGIDLYDGEAVFLITPRKGYCITKRLIASKMTPAASFLKTEVVPYGGMLEGALAKIQKLGLKRVAFDPALIDLERGAGLLKAGLCKTSSLIGEMRMAKYADEVAKLRKACQIAWNSFEEVKPQIKTGMTEEDVRILMALAMHKRGADSIPFNIVCFGENTADAHHTPSKTRKLKAEDAVLMDFGCYYEGYTSDMTRSWWHGKKEPAEYTKIWNIVDQARQAGIKALRAGVSAGAVDAAARTVIERAGYGKEFFHTTGHGIGLQEHDRPILRAGAPDVLEENFVVTIEPGIYFDGRWGIRLEDSFLVTKNGSKKLTQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN7</accession>
    <name>A0A1Y4DBN7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56275">
        <property type="protein sequence ID" value="OUO56275"/>
        <property type="gene ID" value="B5F75_06570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="116" mass="13013" checksum="171729CC1FD5AD0A" modified="2017-08-30" version="1">MCHKCDCAGKGLAAFLLGAIVGAAAGVLFAPAKGETTRRKLKRWADDTYEEQKEYVLEHAEDLKGRIKEHAADLKEKISAHAEDARERLAEGKDKVVKEFNRRKDEIAAKFKKDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR4</accession>
    <name>A0A1Y4DBR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56587">
        <property type="protein sequence ID" value="OUO56587"/>
        <property type="gene ID" value="B5F75_05180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013277480" evidence="3">
        <location>
            <begin position="20"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="87"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="256"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="387" mass="44814" checksum="623295ACA9606C86" modified="2017-08-30" version="1">MRKVLGIIFCLCIAMGAFAQTASQLFAKAKAENNPNTQIKLLTKVIAKSPRMADAYHYRADAYLSLGRNKQALADYSRTVSLRPRDPFRYYARGLAYQKMGRYSLAQADFSKAISLKPSYRNFYLARARANASLEKYEDSLRDYQKYLGKRKPSLELSKEMIPVYLGAYRYEEAIKRLKQLRAAGDDSADLYFWMGRIYSGQNRLDEAVSAYSKAINREASYAQAYRYRASAFKDMGDKPAALEDYTVLLKLQPEAIFYNRRGLVYEEMKQFKEAAADYTRAIELMPKWAIPYNNRGFAKMNLKDWKGAKEDLETAIKLDGTSPTPYVNLAGVYWLSRKDRKNTYDNLDKAVRRNFKNFESLYDDDQKGWMFKNINKTAEFRAVLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY8</accession>
    <name>A0A1Y4DBY8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56643">
        <property type="protein sequence ID" value="OUO56643"/>
        <property type="gene ID" value="B5F75_05485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="99" mass="10859" checksum="6752514728783235" modified="2017-08-30" version="1">MEFEIGQIVDKENYTQAAIWCNKNGAHIEKQGEDYVIMANPEPAVPTAEEQVRTKEAQTGLTRAVRELVLAEGSGASEYVKAKAKEIEALAAPLREADQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC01</accession>
    <name>A0A1Y4DC01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ORF">B5F75_05400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56684">
        <property type="protein sequence ID" value="OUO56684"/>
        <property type="gene ID" value="B5F75_05400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="166"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="178"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="418" mass="46437" checksum="BEA8F370E65D53EF" modified="2017-08-30" version="1">MDARALNKLSMPELTKLAVNYNLEDISGLRKQELIGRIVAVQAKQNGSVYGGGVLEILPDGFGFLRSEENNYLAGAEDIYVSPSQIKRFGLRKGDTIEGLIRPPKDNERFFAMLQVQKVNGVDSDKVYNRPLFENLTPLHPNERFTLELDKNSLTQRVIDLIAPIGKGQRALIVAPPKSGKTMILQAIARSIAENYKDAVLMVLLIDERPEEVTDMSRSVKGEVVASTFDEPADRHVQVAEMVLEKAKRLAEQGKDVVILLDSITRLARAYNTVAPSSGRVLTGGLEATSLQKPKRFLGAARNIEEGGSLTIIATAMIETGSRMDEVIFEEFKGTGNSELCLDRKLSERRIFPAVDINRSSTRKENLLLSEDELNKVWIMRKVLAPLSSVDAMTLLLEKLSATKSNKDFFKQMEVNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC69</accession>
    <name>A0A1Y4DC69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56656">
        <property type="protein sequence ID" value="OUO56656"/>
        <property type="gene ID" value="B5F75_05550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006944">
        <property type="entry name" value="Phage/GTA_portal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04860">
        <property type="entry name" value="Phage_portal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="701" mass="78495" checksum="9ED30D766F05C5D4" modified="2017-08-30" version="1">MMKIKEKLQRFGRKLLGINGDVSPSGWVTVSGTAYDDERLRNSFLEANIRAISTAFCNGEIRLHSADGEEIPYERKGVNPLLDLLYQPAPFLTENLFKQIVSAQFLVYGDVYILKDARNNSGQPTRLIPIPAPSVEIIYDSHTGYPARYQVSTTSGSYNVPAEDMMHVYEGVADTLFEGRSRAALCTLDAKTIQAAKTFNLAFFKNGASVGGVVTFPDNVNLSAQQQAEILAFFNDRHQGADKAHRTAILGRGGKYESHKTSHKDMEYAEGQKFSMQQIYSAMGVPPALVGLFEYAPQFNTKEQQKIFYETTVMPMARLFSDAFNENLVGDFYKNEDVYLDYDFSKVKALEKDWSVLAAAAAQLTTIWPINEVKRALDLPFSDLPGGDEAPDPILNAFGGFSAGKLPQGYKGVSRAAKRALRPNSAQRRFHKKARLRLIEEQSEVMRKSITDHFNTQAEQVRAWIKANEDKTFNYDEALGGMTAQRNALLALKVPALSEIYKAGILFEQDYLQLLDPEKDYRFLSKKDTYDRVAQWAQQYAFKWADSIERTTWERLDKIVKTGIANGKSNRDINNVILQFFAEEGYEPADLIAEPAGDSVRHVSIYDRVGIITQTETRATISEAQLEAYRTTPFVTGKEWITTMGVIDHHEGHLEMDGQIVGINEKFKNPATGQETEAPGQFGTADQDINCLCDIAPVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC70</accession>
    <name>A0A1Y4DC70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56465">
        <property type="protein sequence ID" value="OUO56465"/>
        <property type="gene ID" value="B5F75_04535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="223" mass="25586" checksum="1BAD38E499978A1C" modified="2017-08-30" version="1">MVDIVRKTTSLNDPLHVGFVRTYYVDGKEVYSETLDKNLDIEKHSGTMPDGTVKEFFENGKLYFECEFKNGQRNGACKIYFDNGKVSIEKFYENGMLQGKARVFHPTGRLYKEFSYVDDIQDGKQVKYYPDGKVLETAEYKKGYLNGICKVYTPDGDLRSECTYKNDKIVGDKIIYHPNGTIALISPHKDGKPHGVTKKFSETGELIEEWFFEDGILTLKKVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC78</accession>
    <name>A0A1Y4DC78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotran_1_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56475">
        <property type="protein sequence ID" value="OUO56475"/>
        <property type="gene ID" value="B5F75_04585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="62"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="401" mass="45104" checksum="862A67D90973F24A" modified="2017-08-30" version="1">MNYNQLFSQVVSRSKASAIRELLKVISRPEIISFAGGLPDPTLFPTREVADIMGKVVSEHPRESLQYGTTEGQDRFKKELIKLLKETENIDVTPEQLLVVSASQQALDMTARLFVNPGDSIITACPTYLGALQAFQVAGADITGAESDEGGVIAEDLEAKLAGLQKQGKQCKFIYLVPDFQNPTGTTIPEERRLKILEIAKKYNTFILEDSPYRQVRFEGKSPRTFYELDKTHNHVITLFTFSKVFVPGFRLGYIIGPEEVIRKYVILKQAMDLCTSPILQLATGEYLRRGLLLPHLNQIIATYREKRDLMLKTLAECMPKGVSWTHPEGGLFLWLTLPKHINATELLPKAIENKVAYVAGVDFYPAADVFNDMRLNFSYPSKEQIVEGLKRLAQTIKAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC83</accession>
    <name>A0A1Y4DC83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">16S rRNA (Guanine(966)-N(2))-methyltransferase RsmD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56192">
        <property type="protein sequence ID" value="OUO56192"/>
        <property type="gene ID" value="B5F75_06130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="200" mass="22401" checksum="9E7FF90BD51CC1CA" modified="2017-08-30" version="1">MRIIAGTARGRRIFSVSKNLPVKPISDRIKQSLFDILRPRITGAIMLDLFAGTGNVSLEALSRGAQKTVMVDREPACIKNIHRNLEHLGFADRAKVLRGDVLKPLDWLLPYSDNEGYDIIFMGPPYRDINNKMLAFSQPALANVASARLLAPNGIIVLQTHKTEEFDVPQGLEIYRVEKYGDTLVHFLRAAQPLKEDSHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC85</accession>
    <name>A0A1Y4DC85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dUTPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56485">
        <property type="protein sequence ID" value="OUO56485"/>
        <property type="gene ID" value="B5F75_04635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="143" mass="15365" checksum="FE0442244FA80920" modified="2017-08-30" version="1">MNPITIKVKKLDPRALLPHRAHPTDSGADLFALERTVLPARTVVKVRTGIAVELPENTSGIIWGKSSVESKGIKAMAGLVDAPYRGELLVCMYNLNETDFVFEAGQKVAQLVVLPTIYPAFEETDTLSDTARGAGGFGSTGEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG0</accession>
    <name>A0A1Y4DCG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF1232 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02785</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56787">
        <property type="protein sequence ID" value="OUO56787"/>
        <property type="gene ID" value="B5F75_02785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010652">
        <property type="entry name" value="DUF1232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06803">
        <property type="entry name" value="DUF1232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1232" evidence="6">
        <location>
            <begin position="34"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="105" mass="11843" checksum="1B9E7E88CF35FBB0" modified="2017-08-30" version="1">MKFSPTTVFQDVTSFFPMLWAIVRGRWKMPWNTLFWAVLCVVYLLSPIDVLPDVMPIIGITDDGAFILLVLTLLHKDLSAFRAARAEAKNVLEAQVLPPDPADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCP9</accession>
    <name>A0A1Y4DCP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56796">
        <property type="protein sequence ID" value="OUO56796"/>
        <property type="gene ID" value="B5F75_02830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012034178" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="840"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="906"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="929"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1157"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1455" mass="155044" checksum="D954E8DFAE789A55" modified="2017-08-30" version="1">MNKLIALVLSISLIFGSITPSLAQSNKLMKGAQKALQQSGKEIAGAGAQLPKTLEQAAGVSAAQTVKKALSASAAVEGVSAAVTNSAAKPNASVSVNTAPKVPDFGGRLEHEILAQTKAHQTAPKTLKEIQAILARTDFSAQDAQSVYNQIFNVDSRSASVKEFLLLNTLPSVAVERGFALSEQHAALAVDFYRRTLLSNLQEGPAFADSVSLEELVSLSPKNPEFAKLDKWSRSMAAVTDLGFYGSAKDAALLLNVYAKTPAALKPVTEVIVGRALLNLQAYKELEEMAAMAAENGQLSSEFWKGLQSYSNQQGLSLSLPSVAAKLDANTSSQLKRILKPWSELNVRHLDFSAKATEDWVALNAGKGKVIAAPVQKEGLAKEAATDDVFTPSLDLNLAGLQAMNDLSVGASPVPTSAGETIIPSVPGDPSTGEGPGGIIARVNSRYANVSYTKPVSQALQYGLEKAERKYIQEYGKTPVLEDKAFQKLWVESVKPELEKLAASNRKLTAKVQNDVIATLEASFDPEHVIAPIEKVSVFKKISQYFHNRADRAAAARANRAAQEASITGLEVSYPASLESAPGTFIPQDYEVKFVFDSEATKRAFLNVGKLDSETFVIDSNGSLLLRAPSGAVRGLMGVQIEGGNAATKQVFRALSSHRLAPRFEAEIAKGEDAVMDLLTEVRVPLRTILPGSLLEANPELKQFLVAKDLESAQAAFRNTGKVMESANAVSAVLKDLAAKNPATDQIEFHLFTDKAGDWALKLTAFSEGLSSFGQAISAATKVFGNISSFLTNLPSSAGQFGPALAPFISGLQSKFGLKHTAYMGQALSAVGLGISAGSLAMGAMGMLPAMAAFIGMVGGILVNGIAGNGIIKQTNSPIAKAIANDPVSASSTVADLNSWASAGGIYCYLFLPIVGAVTTALFGTGVGLGTLAAMFGVAAVAPVVSSLLMKASKITNIRETLKEKNKDGSTKTFLQGVGANLKYAFTGTQKQELEQLINKKAAKKGVAPETIKPTAWMKAKSYLNQYLVQMAGRVGLYHFGGMVFNSGPGTVLKEVFAKPEQAMLASFLAVYLTVFAGRKLGAKAMGRGLITDKALIGLSSLIAVGAGALSIIPGLDIYTRSGLWALAGLGFANLANQEQAMALNRPENADKKAAVSMIYVLARLTGMGTIIYGMLSDSIAALPGMTVAQGAIYGLALPVAATLLATLWNKSLITKDLKDQFRIWMTKKPKLLSYPILRSEVESALTKNPNLGTSLVMDDASQEVIKNLGDGLMSRYRVDLRTLEQTMISVNDKAALDLHRLDMARKLYSRLPENTRLATGNPLTYEQFRAEVEPLYNSIVKARATGASEESVNKLINDSLTGIMAKYPVGRADVRVIETRLMEKTRLDRVRIATMKYIYGKQLTKEAETEIAAQLKKVPADTDKQEVIDHVLEKYQAMAKARGVDFILPSNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ2</accession>
    <name>A0A1Y4DCQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_03320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56887">
        <property type="protein sequence ID" value="OUO56887"/>
        <property type="gene ID" value="B5F75_03320"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="500" mass="54090" checksum="E2996624805D041F" modified="2017-08-30" version="1">MKINLVSFNPLAADTADNSARVLDLLRAPAPQADIWVLPEAALCGCPLFDLFDDKRLLAQNLAALKEIAKETKETAVVLGYMDKQNGAPATAAAFIYKGKITKIFDTETVSYKGKRLQLVLGTPDQAPADPDADAVLFLAARPYLKGNIAPRVDALKKFAKKHGVPSLLCCLLGGGDGMIFDGLLAAADKKGSLILLGEPFREQTLTFDLDEKYTPVSYKKPWQEELLSALAFGLRDYVHKSGMDKVMFGISGGIDSAFTAVLAAKALGGESVYCVSLPSYCTSDLSKTLAGQLARTLGVNLEEVGVIPALGGVKEAISHIVSHPKDTTEQELQSRLRTTILGALASEYHAMLISTDDKSECAVGSFVLYGDAGGSLQPIGDLYKSEIYELAEYINKQGELIPRGIIERAPTSELSPNQKDEDQLPPYSVLDKMLRAYLEEGKTPEEISKKFHVKAAVVQDVLTRVNQADLKRRQTAPALQVSAHPFASVLRPIIKKVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU5</accession>
    <name>A0A1Y4DCU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphoglycerate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56943">
        <property type="protein sequence ID" value="OUO56943"/>
        <property type="gene ID" value="B5F75_03610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="4">
        <location>
            <begin position="3"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="5">
        <location>
            <begin position="104"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="317" mass="34115" checksum="FF4FF02593C6B910" modified="2017-08-30" version="1">MKILIADKFPAHWKEVLSKEGHHITDNPALDENTLPAAIADNEILIVRSTKVPAAVMDAAANLKLIIRAGAGTNTIDVAHAAQKGIAVCNCPGTNSIAVAELTLGLILALDRRIYHNTKDLREGKWNKSEYGKAKGLFGRTLGIIGLGHIGKEVAKRAEAFGMKVLAYDPNDKAEEFRAAGVTPEPDIYTLAAMSDVITVHIPETPQTKGLFNKKFFDAMKPGAIFVNAARGGLVVAKDLADAVKNKGIKAGLDVYETEPKANDNTFDYSPYQGAENLYGTHHIGASTDQAQDAVAECTVQIINQYAQDGTFLHRVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD36</accession>
    <name>A0A1Y4DD36_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57044">
        <property type="protein sequence ID" value="OUO57044"/>
        <property type="gene ID" value="B5F75_04140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="67" mass="7548" checksum="EC8A42365CE5CC3E" modified="2017-08-30" version="1">MPKGKVKWFNDQKGYGFVTPEDGSKDLFVHYQEIQGDGFKTLAEGQEVEFEVVESEKGPKAVKVVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD66</accession>
    <name>A0A1Y4DD66_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="8">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="8">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyQ</name>
        <name evidence="9" type="ORF">B5F75_03210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57073">
        <property type="protein sequence ID" value="OUO57073"/>
        <property type="gene ID" value="B5F75_03210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="291" mass="33873" checksum="752E9E01187F5B8B" modified="2017-08-30" version="1">MNFQDMISALNTYWTKQGCVLVQPYDVEKGAGTYNPETFFGSLTTKPVKRAYVEPCRRPADGRYGENPNRLGKYYQYQVIMKPAPANIQEIYLNSLKAIGLDPKQHDVRWIEDDWQSPTLGASGVGWEIWLDGMEITQFTYFQNMAGYALHPITVEITYGLERIAMYCQKVDNVFDIRWNDEITYRDVHHEGERQFSHYYFEESNVDHLRRYIQECEEECMALCKKGLYLPAYDNAMKLSHYFNMLEARGAISVSDRTNNITKIRNLAKACAKTYVESVEKQEHQNEEAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDA5</accession>
    <name>A0A1Y4DDA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57057">
        <property type="protein sequence ID" value="OUO57057"/>
        <property type="gene ID" value="B5F75_04205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="156"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="373" mass="42366" checksum="B4956D7884412C58" modified="2017-08-30" version="1">MEKQVKILVVDDDNNLRETLVDLLEIEGYKVYQAGDAAECLEICANEFFNVILMDYNLPGETGLDLIRKIRSFNQDSQIIMITAYASLNAIMEAMQESVYDFLMKPVDFDYLKRTINRALDKYFLEQSNKELLAQLKTRNEDLDRLNNMKSKFFSIVSHDLSNSLMTLKMSFDMLKKKMNPDEDQKKKMMFMDESISQIEHLIKDLVDWAAIEKGKLRIEKTRFELTESLKKTVEIFRAKGAKRNIRVTFESCGAVPVFADEKRIRQVISNILENAVRHTPDNGTIEIVVSKIDEKNAKVSVTDSGDGIDPEQAPNLFTSFTQLGDKSRVGRLGLGLSIAKDIVVNHGGRIWAHSEGLGKGATFNFTLPITNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDN0</accession>
    <name>A0A1Y4DDN0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CDP-glucose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57223">
        <property type="protein sequence ID" value="OUO57223"/>
        <property type="gene ID" value="B5F75_00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05252">
        <property type="entry name" value="CDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013445">
        <property type="entry name" value="CDP_4_6_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02622">
        <property type="entry name" value="CDP_4_6_dhtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="14"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="360" mass="40794" checksum="34AABA706BA4BBEA" modified="2017-08-30" version="1">MNQFNGVYKGKTVLVTGHTGFKGSWLAIWLTALGAKVVGYALDPYSDRSNYCASHLKERLFADERGDVRDSARLEEVIAKYKPSMIFHLAAQALVRTSYEYPKMTYETNLMGSLNILEAVRKFDFIKQVIMITSDKCYENVEQIWGYRETDRMGGYDPYSSSKGCAELMISSWRNSFFNPKDYAKHGKAVASVRAGNVIGGGDWSDNRLIPDCIRAIEAGKDIEIRSPQATRPWEHVMEPLSGYLKVGEKLVEDPVTYSTSFNFGPKIEANRTVWEVVQKCVAYYGKGKVVDVSAPGAVHENTLLSLDVTKAYRMLDQWHAKLSFDEAIEFTVDWYKEALNGKDMWDYCVKQIQAHDEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT3</accession>
    <name>A0A1Y4DDT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein B5F75_00305</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57257">
        <property type="protein sequence ID" value="OUO57257"/>
        <property type="gene ID" value="B5F75_00305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00252">
        <property type="entry name" value="TIGR00252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="119" mass="13360" checksum="D16DCEEB4FBE3F60" modified="2017-08-30" version="1">MNTTWKGKAGEDRAARFLEQAGWRILERNFSARGGEIDLIAADGKTLVFAEVKTRSYQAFGGPLAAVTPAKQKRIAQTALHYLQERGLKFDSIRFDVLCVLPDRIEHIPNAFFPPRTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX2</accession>
    <name>A0A1Y4DDX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PilZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57297">
        <property type="protein sequence ID" value="OUO57297"/>
        <property type="gene ID" value="B5F75_00520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PilZ" evidence="1">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="154" mass="17305" checksum="BD6BEDA03EC6F9E4" modified="2017-08-30" version="1">MTKNFSEKRRHPRMPVISNLIEPVNLHYKTEDGKETSLVAILADLSASGMRMISFLGAPLADRFSISLQLPGTGKMEVEAKLAWVKQRENVYTIGIEFIKMADKDAKVISEMADDFNDCDTRILLKLPEVCVAGCKCHKICNKIQKDESLFEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE07</accession>
    <name>A0A1Y4DE07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="9" type="ORF">B5F75_00850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57354">
        <property type="protein sequence ID" value="OUO57354"/>
        <property type="gene ID" value="B5F75_00850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="170" mass="18339" checksum="DCE795EC4DCB7D7D" modified="2017-08-30" version="1">MKVILKQNVKNLGMVGSIVDVKPGYARNFLIPHRLAELATEGAIKNWQLGAERRAKRIEAELAEARAIAEKLAGVVLPFTKTVNSDGVVFGSVNKADIYKALNALGHNISKDAIELNMPIKALGETEVGIYLKPTVTATIKVQINPLTTVEEKVADAKPEEKAEAVAEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE44</accession>
    <name>A0A1Y4DE44_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lpxK</name>
        <name evidence="14" type="ORF">B5F75_03505</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56922">
        <property type="protein sequence ID" value="OUO56922"/>
        <property type="gene ID" value="B5F75_03505"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="71"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="379" mass="43495" checksum="F18F6B7810C906AD" modified="2017-08-30" version="1">MLKYLKPIFEECMDLLELKENLQQNALGRGVLLVASKLYGLGAWLDRASYENGWKTAQSVNSRVVCIGNITAGGTGKTTAVLLAATTLAQEGIRVAIVSRGYKRQQKSNEPVVLFDNPDADWRLAGDEPFMMSRVLSQYKVPIVICPNRAEAAKEALRRFKSQIILLDDGFQHHRLRRDANIILIDAKNPFGNYHLLPYGILREPLSALKRASLIVLTHCDQVSDRQLEDIRDQIRLQNDTVEILESVHKPEYYFDICNTKKVELKDIQGPAACFCALGHPETFEKTLENLGLELKQKWRFPDHQFYTEENLRTFEETRGDLPLITTFKDFVKFPDNWRDILTKNVYVLSVNLKIRGGEKEFDKFTDVLYPKFSKIKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE95</accession>
    <name>A0A1Y4DE95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57453">
        <property type="protein sequence ID" value="OUO57453"/>
        <property type="gene ID" value="B5F75_01385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="339" mass="37341" checksum="1B6046A1F6CA4D59" modified="2017-08-30" version="1">MFSDKPTFYYLKASTICLTIIAAGIVTAFLVYTKSLMIPLVISILLYTILAQMTLYMKHKFSFPSWLAMTVSILLCVALFVGVIWFTANSVGTFLKGAEVYRQNLIDTINDIATRLQQHGITFDQKFIENYLRELPLFNWLKNFGGKVFNIVSDATLVVLFMTFFLFGSKKTPPITNPAIKEMLANVSVYLSVKLIASLATGLIAAGILFGFQVKLAALFALFVFLLNFIPSVGSIIAVLLPAPVLFLQYGLGPQFFVVIGLLTATEFTIGNLLEPRFLGEGMDLHPAVVVGGLIFWTLVWGVPGAFLSVPITASIKIVLSKIKHTRPVAEFLAGRLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE98</accession>
    <name>A0A1Y4DE98_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_00920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57366">
        <property type="protein sequence ID" value="OUO57366"/>
        <property type="gene ID" value="B5F75_00920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="125"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="233"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="547" mass="60097" checksum="18F6BCE5FF4A4866" modified="2017-08-30" version="1">MAKNDLTTRNLMLDSLKQYAKNRISFNLIREHDAKNEIPLDILKEMYDHDVLGVHLLLIPEEYGGLGGQTTEIYRVCEQLARIDLGIATGVFATFLGSDPINVGGTPEQKAKWFKKIAQENKLVAYGATEADAGSDLVSLRTRAEHVVKDGKVVGYKITGSKMWISNGGVADIYTVLALAPGGPSWFIVERGTPGFTQDVHEDKHGIRLSNTAGLAFDEVYVPAENLIGLKEGQGFLQAQAVFGYTRLMVAAFGLGGGEEAVETALQYAQQRIQAGGPLAEKQGFMLKLITPHYVRFEAARAYIDWTAKQLEVNNHGLATEGAIAKLYATETGNKAAEDSIQAMGGFGYTKEFAVEKIKRDVKITCIYEGTSEVLEMTIFRGRWQEHLKSRGQYYLNQAAEFDAIHAQNPNVGADSVALGFRALARVLEDCRANKLTRHQYVTFMLGDLISEMEVAAVFSRQCANKVITEGSRFDLNTLSTMARVNARQSAFKTATEGMRLILGTCPNSNAADLSQGVNLVGIEEKMRGIIDDMDVVSAKLREVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC3</accession>
    <name>A0A1Y4DEC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57503">
        <property type="protein sequence ID" value="OUO57503"/>
        <property type="gene ID" value="B5F75_01650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="18191" checksum="9C3B8E8CD7361DBC" modified="2017-08-30" version="1">MCNSFCFKQHVSTSGFTLIELLVVVLIIGILAAVALPQYDRSVLRSRMATAKPALVSLKEAIKLYHLETGTWPTSLEDLTIQIPENEGYWIHSPIAAWGAESAPLAVWTGLTQNGTTFGLVLPVASNDWVCCGNAVADTNQVQELCEKAGYREYIQSPTGGLRGCYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC7</accession>
    <name>A0A1Y4DEC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57504">
        <property type="protein sequence ID" value="OUO57504"/>
        <property type="gene ID" value="B5F75_01655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="199" mass="22854" checksum="B5AB4B6D9A04B6B7" modified="2017-08-30" version="1">MKDIVFDLGGVLIDWNPRYLYKKIFASEEEMEWFLSNVCTPQWNTQQDAGRPFAQGIALAKEKYPKYAPQIEDYYKRWEEMLGGSIKGTVAIWRELKDKGYRIYALTNWSAETFPIAKAKYDFLQQMDGIVVSGEEHLVKPDPEIYARLLKRFGLHSPNCVYIDDNAANVSAAAMLGFDAIPFQSPDALRMELLKRGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE7</accession>
    <name>A0A1Y4DEE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57436">
        <property type="protein sequence ID" value="OUO57436"/>
        <property type="gene ID" value="B5F75_01295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013232118" evidence="1">
        <location>
            <begin position="21"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="232" mass="24877" checksum="E4A21BB18342DD3C" modified="2017-08-30" version="1">MKKLIALLVGVFCLAGAAHASNIADDFRAHYSAASDLAAYNKDLNSLIGLADFHTGKGTSFPGFDIGASLNAVKTSSDNNIFSDDYMYVGFITAETKIPVLNLGVVLRGTDMNGFKSLGGGLKYNFGLFDTIHLSLAGFYDRGSTDWYTTDHYSLSAVASMNVLFLTPYVGVGYDYGKLETKDLLPSRSTSDGDIRYTAGVNLKPFPFVYVFAAYTKTASSHGLQGGVGLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF5</accession>
    <name>A0A1Y4DEF5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alaS</name>
        <name evidence="11" type="ORF">B5F75_01860</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57543">
        <property type="protein sequence ID" value="OUO57543"/>
        <property type="gene ID" value="B5F75_01860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="10">
        <location>
            <begin position="2"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="557"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="561"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="667"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="671"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="870" mass="96282" checksum="C016AFCB66C87C9B" modified="2017-08-30" version="1">MKTSTEIRNGYLEFFHSKGLPILPSSSLIPHSDPTLLFTSAGMVQFKANLLGIDNSLKNAATCQKCVRTTDIDSVGFTERHLTFFEMLGNFSFGDYFKKEAIDWAWEYLTKVLAIPADKLYVSIYKGGIAPRDAEAYEYWRKYVPADRIFELGEADNFWTMGPTGPCGPCTEIYYDFGPKGCKNPHCDITCDCGRFVEIWNIVFESYNRQEDGTFKPLPHNNIDTGMGLERLCMAMQGAKNVFETDLFTPLTAQAKKDLHITGETKEEISALRIIADHVRSSSFLIAEGILPSNEGRGYILRRLIRRAARYAKLMGNDKPYLYTLVPVVQRIFAGLYPEIDKNLSHIQDVLKQEEKTFLKTLVTGEEKLAALLAACGKTLPGEEAFHLHETYGFPLELTKEIAAAKGVAVDMAGYEKAKEAAQEKSRSYADEFTKGKAVMMQKLENGYPATHFTGYDTLEDAAEVLALLNDKFEPCDSLQGEGYAVFNQTPFYAESGGQVGDKGLVLAGGKEIARVEDVQKPLGKVYLHKVNGTLKKSERVTLRVDAALRKRCMANHSAIHLVNAALRQVFGTSVHQSGSYVSPERFRFDYTLSKTPSAEELNRAWQIANQAAEAALTVTCQVRPLADAEKLGAVTLLGETYADPARFVLMGGDFEHPEQKYSLELCAGTHVKNTADVITVLVLKEGSVSAGVRRIEGVAGYAALDYLKEVNRQADALAARLEVPAKDVFTRVGAIMDELKEVKRRYTQFRERTLVAGGMNEMTFTMKNGSSLVLRQADGAEPKELRTIADTVAQKYKQALIIVMCDKEGKRSFVVKMAGKLPNTDAVTVAKMIAADLNGRAGGRPDFAQGGGEAKRPWRDLIGQLQETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH7</accession>
    <name>A0A1Y4DEH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57487">
        <property type="protein sequence ID" value="OUO57487"/>
        <property type="gene ID" value="B5F75_01570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="11085" checksum="21310218F8614E7D" modified="2017-08-30" version="1">MAKLTNKMLSKIDLDEQRKYVGQLDWFNKKASDFFQRKGISFANFQAGMPFDAGMPLNPINISSFNAEDDLYIEQLLEPVILCEGKVVRRGAAILGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ9</accession>
    <name>A0A1Y4DEJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA (Adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57325">
        <property type="protein sequence ID" value="OUO57325"/>
        <property type="gene ID" value="B5F75_00680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="40"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="231" mass="25763" checksum="C161E4417FB246AF" modified="2017-08-30" version="1">MQSGKLVTLAMDTSASPLLLTLEKDGKIYTVRRKGVKQEKLLFPALHTLLAKAGASLNDIGRIFLIRGPGRFTGIRISLTFASMMKYLNHTEVRGTTMFEAVRFQTLASRKFQTWQKQHPQGVLAVVLHAFREEYFLQIFDAKNEGPAWLSREELLARLAAYAQPLFIAGSDKDGAGLEGLVGSGYALAEPKACKLQPARLLEMAAEERWTKDALEPLYLKPARFELVKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL4</accession>
    <name>A0A1Y4DEL4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56159">
        <property type="protein sequence ID" value="OUO56159"/>
        <property type="gene ID" value="B5F75_05950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="103" mass="11513" checksum="F04C0605859D773C" modified="2017-08-30" version="1">MTELQQTARLFKTLSDENRVQIVQLLARRGEMCACQLLELLHIGQSTLSHHMKILCDGGIVSARKEGKWMHYSLQASGLQKLLHCLKQLSAPVPKKACAACKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL8</accession>
    <name>A0A1Y4DEL8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplM</name>
        <name evidence="5" type="ORF">B5F75_01720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57516">
        <property type="protein sequence ID" value="OUO57516"/>
        <property type="gene ID" value="B5F75_01720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="141" mass="16097" checksum="B1B302AAD3090576" modified="2017-08-30" version="1">MTKTFLPSVKEVETTRKWHHIDATGQTLGRLASQIAVLLMGKHKRTYTPHMDCGDFVVVTNAGKIKLTGNKMEDKVYFSHSGYAKGAKETPVKRVLEKNPTRVLELAVKRMLDENKLRAPRMKRLRLFAGEEHAFTERFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM1</accession>
    <name>A0A1Y4DEM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_06005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56169">
        <property type="protein sequence ID" value="OUO56169"/>
        <property type="gene ID" value="B5F75_06005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="157"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="204" mass="22121" checksum="DFE2952548CD2116" modified="2017-08-30" version="1">MKILIATGNPHKFKELIHILPAKLKNGTPIEYVSLADFKGLTLPPETGNTLEDNAETKAVYAARESGLPAVSDDTGLEVKFLHGAPGVHTARYAGEHADADDNNRKLLAALEGQLLPARAASFRTVACLATPQGRVQLFDGTLDGFIGFGYKGENGFGYDPIFLVGSSQKTLAELTEREKNQISHRAKAFKKLADHLVLLKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ2</accession>
    <name>A0A1Y4DEQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="9" type="ORF">B5F75_02185</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57604">
        <property type="protein sequence ID" value="OUO57604"/>
        <property type="gene ID" value="B5F75_02185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="128"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="330"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="401" mass="44955" checksum="61730B372573D132" modified="2017-08-30" version="1">MEPEAPFRGQVFTVTAITLALKQMMEGVFRDVFVEGEVSSLREAASGHIYFDLKDRESLLSAVMFKWDARKYGFELQEGVQVRVWGSLSCYAKQGRYQIVVKTAEALAKGNLFLEFEKLKKKLEAEGLFAPEHKKEIPAYPQRIGVVTSPTGAAVRDILSVLKRRSPHLEIIIAPVLVQGEEAAGQIAQAIADLNRFKPAPDVLLVGRGGGSMEDLWAFNEEIVARAIYKSKIPVISCVGHEVDFTIADFVADLRAPTPSAAAELVVQNSQNTRQYIRQLQKRLLQSVSLFYERARNRFDQALNSRVFKNPETIFQAKEQELDDLSLRLENAWKEKLSNFTHRFELARNQLQALGPQAVLKRGYSITRKADGSVISRVGQTAPGETVFIQVQDGMIRSEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES8</accession>
    <name>A0A1Y4DES8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">B5F75_02285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57624">
        <property type="protein sequence ID" value="OUO57624"/>
        <property type="gene ID" value="B5F75_02285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="136" mass="15571" checksum="F7952564FD3CBB0E" modified="2017-08-30" version="1">MSNRRMARECALQSLYYADSAKDAQEKDVLRYAADFKRELGDCYPFCQDLVSGTTEHLKEIDKLVSAYAKNWTVARMSAVDRSILRMATYEMVFSPEKTPVPAIIDEAIELAKKYSTENSSKFINGLLDQLKKERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW5</accession>
    <name>A0A1Y4DEW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57637">
        <property type="protein sequence ID" value="OUO57637"/>
        <property type="gene ID" value="B5F75_02350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005534">
        <property type="entry name" value="Curli_assmbl/transp-comp_CsgG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03783">
        <property type="entry name" value="CsgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012983314" evidence="1">
        <location>
            <begin position="21"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="226" mass="25017" checksum="EA35DD027939A35F" modified="2017-08-30" version="1">MKKILTLALFCLLALNGCTPKTVISKTYNFDQMNRIGVMGFSNTWPAMQGVENLFAKYLIDAGFKVVERAQLESVLKEHNISVSGYLSPETTREIGKILGVDVLLIGEVSSYTPARTELTMTATRRTEARPVYTQDVMQLPDGTYVGYTRNVGTQYTHSTDVRPTEYTINARVGIIAKLVDVETAEIIWIGSDEASSSSALDAADYIARGLVKSFTKELTKLQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF11</accession>
    <name>A0A1Y4DF11_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57666">
        <property type="protein sequence ID" value="OUO57666"/>
        <property type="gene ID" value="B5F75_02510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PTHR23222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="29"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="269" mass="30337" checksum="6C621566DBE271D5" modified="2017-08-30" version="1">MRNITPISVSWKKLAVPIVALVLLIGVFNSFFTVSAGSVAVKLRFGKIVGAYGEGLHAKVPFVDKVEKFSVRIKKDSFQTEAFSKDLQTVGLTLAINHRILPDTIESIYRNLGPQYTATVLKPMVEEWTKAVIAKYSADSLISNRVEVARELDQILKEKMKEKEVIVSDIAITNFEFSPQFLKAVEEKQIAEQEAKRATNLVEKVKKEAEQKILQAEAEAKSLRLQREVVSDELIKLRQVEAQLKAIEKWDGHMPTYMAGDQMPFVMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF13</accession>
    <name>A0A1Y4DF13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57714">
        <property type="protein sequence ID" value="OUO57714"/>
        <property type="gene ID" value="B5F75_02135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="127" mass="14624" checksum="F87C2C96F46047A0" modified="2017-08-30" version="1">MKKKKQEYKCPLEATMDIIGGKYKGIILGYLIGRKLRYSELQKLVSQATPKMLIQQLKELEADGMIVRKLYPVVPPKTEYSLSARGKTMIPIIKALNLWGIRYLKEESIPCKYNLDDLSETAKKLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF16</accession>
    <name>A0A1Y4DF16_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tilS</name>
        <name evidence="8" type="ORF">B5F75_02625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57687">
        <property type="protein sequence ID" value="OUO57687"/>
        <property type="gene ID" value="B5F75_02625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="28"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="33"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="247" mass="27637" checksum="246E9955F369FFE0" modified="2017-08-30" version="1">MTKKSFNASVLPRMRAFAGRLIGRGDAVLVGLSGGADSVCLLHFLRYLAGEKHFALAAAHVNHGLRGKDAEADQRFCRQLCKELEIEFLTLKTDAKKYADKFHLSPEHGARKARYEAFVKLARKWGANKLALGHQLDDQAETVLLNLLRGTKAKGLGGIPVRRPLAKGIEIVRPLLCITRAETESYLQNNGLSHITDQTNFEDVYTRNWIRSTLLPLLETKQPQIKSHLSLLAQDITRLLEETSCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF22</accession>
    <name>A0A1Y4DF22_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57697">
        <property type="protein sequence ID" value="OUO57697"/>
        <property type="gene ID" value="B5F75_02675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="219" mass="25355" checksum="E703AEFE25967A1A" modified="2017-08-30" version="1">MKKSETTKTDKSERELRMRQTIKKAAFALMAEKGLDKVSMREIAEKVHVTKPVLYYYFKNKEDLCSSIIDDHEQAFCDQLLTVQQRAQGPEEVLYEGLKSHLDFFTKNPIHSKFVIQMISYTLDMDSSKMPARKQDRYLQGMLERILKEEEKEGKVPAGATTDIVRLVSGIATEIMFSAYLEQHVCRGCIKGSLYNREQIARLVKIILLGIKQYYKETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF56</accession>
    <name>A0A1Y4DF56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2344 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56319">
        <property type="protein sequence ID" value="OUO56319"/>
        <property type="gene ID" value="B5F75_06810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018768">
        <property type="entry name" value="DUF2344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10105">
        <property type="entry name" value="DUF2344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2344" evidence="1">
        <location>
            <begin position="60"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="240" mass="26778" checksum="3DB06605E774BDE0" modified="2017-08-30" version="1">MRAAYGHKKMINTPKIYKMRIVLSGPEKGTGHTNLFNALRNMVLASGLAFEPAKINKNWPRLAYGPAPAFGQRAEREYLDIYLTQPVSAEHVRQALQRVLPQGVALLGVDRVPYALPSVQHLAAAARYRVEGNFELYGPEKTPEEFFNAPRIDLVRRAENGLSLTQDVKAYVAGAELLSPRVLRMTLTCVEGKWIKPQTAVAAWLGLNVPLQDELFTVEGLSFIREGLFWQDSQGALHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF67</accession>
    <name>A0A1Y4DF67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57292">
        <property type="protein sequence ID" value="OUO57292"/>
        <property type="gene ID" value="B5F75_00495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011011507" description="SH3b domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="4">
        <location>
            <begin position="177"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="240" mass="26731" checksum="FF16AF91DF4C031D" modified="2017-08-30" version="1">MKRFLALTLLLVSVASAAWAQTALEQAENFYRQGKFSAALGIYESELKKVPNDPYLYYNIGNCYFKMGSRGLAIANYYRAFRLAPRDADIRHNLTLSLSSVGERLVPSGVPVVLHQAFYSLSYSELKGLLFALLWLFCALASLWLLKRKWGRMLAASAVILLLCAGWFYLRHTLQVEHLAVIAAPVAEIRSGPGTNFPASASLAQGHLITVEDAKDEWYEVIVKSQGLKGWVEKSAVEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFA3</accession>
    <name>A0A1Y4DFA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ORF">B5F75_02240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57615">
        <property type="protein sequence ID" value="OUO57615"/>
        <property type="gene ID" value="B5F75_02240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="22236" checksum="8F076B5D12CD50B1" modified="2017-08-30" version="1">MKKTMSKKHQHKNGGEEAAQALDEQDLPEVREPEIEVKPADEPTPEKKPDYYDQLVRLSADFDNYRKRTEREKASFLAYGKKEFAQKLLPAYEVLLRQRAELAKEEDKGECSASLKAVKAGLNMVFTELEKAFKAEGIEHMDVLDKPYDPATQEVVAMIPSSEDQDGLVLQEVQMGFTMDGKVLRPARVIVGQHAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFD4</accession>
    <name>A0A1Y4DFD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="6 7">Binds 1 Fe(3+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the rubredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57645">
        <property type="protein sequence ID" value="OUO57645"/>
        <property type="gene ID" value="B5F75_02400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024922">
        <property type="entry name" value="Rubredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000071">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000071-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="53" mass="5840" checksum="DDA5901033031DCA" modified="2017-08-30" version="1">MVKYVCEVCGYTYDPAVGDPDNGVPAGTKWEDVKEDWVCPVCGVGKDQFKPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFK2</accession>
    <name>A0A1Y4DFK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57715">
        <property type="protein sequence ID" value="OUO57715"/>
        <property type="gene ID" value="B5F75_02365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012443">
        <property type="entry name" value="DUF1646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07854">
        <property type="entry name" value="DUF1646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="346" mass="37140" checksum="6F72D701B9CAD913" modified="2017-08-30" version="1">MSVVVMTLLSLIVLAALTLPFLVHKVEEELEIFLLVCGVAAVTVSGAWSGHLMAEALKEPVAITAAVLVLGVLFKRFGHHTAHAIHALENKTGPKTLLFLTVFVIGLFSSVLTAIIAALITAEIIKLLDLPARAKTQLAVYACFAIGFGAILTPIGEPLSTIVIAKLKAEPYHADFFFLLRLMGVWIVPALILFAALAARLGKQALTAKPQQQAEAETYRQILLRAGKVYLFVAALILLGEGLKPLAARTITHLSKYALYWINSLSAVLDNATLASIEIMPSLPKETLVFLLASLILAGGLLIPGNIPNIICASKLGIKSRDWARAALPVGILLMLVYFFLLSIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFP9</accession>
    <name>A0A1Y4DFP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VanY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57472">
        <property type="protein sequence ID" value="OUO57472"/>
        <property type="gene ID" value="B5F75_01490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="VanY" evidence="2">
        <location>
            <begin position="174"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="327" mass="38116" checksum="7CEA3C7B10BA06D7" modified="2017-08-30" version="1">MRQFDKKRIFTNPLFVIFIIHSRHAPLYRGKRKMLVSNKHSAVRSRKAGHTVSIKTEIKTPLTGGELLPVAAYPHGTTWRTNMTRKYIFLFSFCSLLTLAADLFAQPATPKQDPQAVLQSVCQSLIQQVDSEEFQKAYLPLEEKRDLLILVDKEHALPSYYKPDDLVRMPRGFLRQEAAVWFAEMEQDARKEGIYLFPVSTYRPYVYQWHLKRRTRNPDQVADPGHSQHQLGTAIDFNTTRLNDPYYRPALEWLKQYAGKYGFSLSFPKGQEEETGYPFEPWHYRYITKEGVALQNKFFGGSQHKMLVFLNMCLWNKPDSKTAIKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFR0</accession>
    <name>A0A1Y4DFR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56519">
        <property type="protein sequence ID" value="OUO56519"/>
        <property type="gene ID" value="B5F75_04820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012463883" evidence="1">
        <location>
            <begin position="23"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="591"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="672" mass="76526" checksum="AC38F8D266A07BC3" modified="2017-08-30" version="1">MRKLRLLVCVFLCFSLGACVHNARKQEALRRVAAHEVEPADAFLSGHTLYIQYDYQGESFFFTADLTAAKSEGNVDIVPLLPRLVRNPEKLDHSRRVVIVGREWTDVLRRTIEPLIPPKQGQGVLLFIQNYETVLLRRADGTPDLVQLKDAPGDIEIVGHIEARQFDVLVSEQLKKMVAATGEPYTRFLLRLDGVPASPFIYLDTAKNANVQLQLPDYYEVKKEMTSLGFSTAFVYSFFVKSHLFSTLKAPFTTVHRLAAFGTSTVYAALPPHAWDLKEVPPLNASGEEMDLADFNRWLDKKISRQNYKAFVTLLIDGEEFFPHFMLAMQRAQESIFTNVYIFMADPYGLSIADVMKARANEGIDVRVIVDELNTVLNSGKNPELKTSETFIMPKYITSYLRKDSKAKARTHLNPWGTFDHSKVYIIDRKLAYTGGMNIGQEYRYTWHDMMVALQGPVVGRLVKTFYENWSFTGWGGDYAAAYRKLFSKRQREANREAPGMIDVRLMYTKPNDSEIFDAQREAIRRAKKRIYIQNAYFSDDRIIKELIDARGRGVDVRVILPGENDVGIMDVNNRAMANKLLKNGVRVYFYNGMSHVKAAVYDGWAVIGTANFDKMSLYINKEMSLGISDPAFVAELTERLFEKDFQNSKELTEPLDIAWTSVIVTALTNQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFU5</accession>
    <name>A0A1Y4DFU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57542">
        <property type="protein sequence ID" value="OUO57542"/>
        <property type="gene ID" value="B5F75_01855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="82" mass="9401" checksum="ECAEAE1A36986053" modified="2017-08-30" version="1">MFGFAPASAQGPNREPGLQEFSVRKITGRRIPYHHLTPRVPLENAGFLINRQFINRQNKKPRRQAGAFATNIELQRFLQLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG07</accession>
    <name>A0A1Y4DG07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arylsulfotran_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56589">
        <property type="protein sequence ID" value="OUO56589"/>
        <property type="gene ID" value="B5F75_05195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004062">
        <property type="term" value="F:aryl sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035391">
        <property type="entry name" value="Arylsulfotran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010262">
        <property type="entry name" value="Arylsulfotransferase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038477">
        <property type="entry name" value="ASST_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17425">
        <property type="entry name" value="Arylsulfotran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05935">
        <property type="entry name" value="Arylsulfotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Arylsulfotran_N" evidence="2">
        <location>
            <begin position="86"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="557" mass="63475" checksum="BA5AE9FCACBF02B9" modified="2017-08-30" version="1">MFVEVKSCPVQSFPPHPLKRTWSEHSLGKCALLFSFPIRFRFYVSFQSSGLCYNNKVKKRTKLFLGVLILAALAAWVVCHSSPRFILNPSGRTPLSGVYKLPFTNQSPLTVTVAGQRNDADITHTFPAGYGRAFPIHGLYPQAQNKITVRYQGKTQEFTVPLPEIRVNGGFVPPAQVVTIEKDPSQKKTDDIYFISASIGEKHPNLSWVILGYSRNGNLRYLNIDDKPRLNELQRIVPEGKEMMLITDIGSETLLGQRRLDLSGKNKIGHHDRVKKGDHFISLANSKWGVEDRVLELDAKGHIVRDLSAGELVRKAVGANPSPAEREMLNRVVFDEHNIYITKKNTPQAIDWAHINSIVYDEKTDMLYCSFRNLGVLAVKYTPWELVWWMVTDKLDFLPPDDPTAKHRRFLDALASLQAYRVRGDGLTDGPKHHHALFLWPDGTLGLFDNRGYAGNKSRYVEYKISGGHGKWTAKKTYEYFDPTLTNNDYTSDIDVLPNGNLLILYGMEQVVVEVDKNTKEKRYQLNFALPTEMIYRVDKMPFYPTPGREYPKEHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG78</accession>
    <name>A0A1Y4DG78_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA gyrase subunit B</fullName>
            <ecNumber evidence="10">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gyrB</name>
        <name evidence="12" type="ORF">B5F75_02440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57652">
        <property type="protein sequence ID" value="OUO57652"/>
        <property type="gene ID" value="B5F75_02440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="429"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="823" mass="91587" checksum="8907EE0456661F30" modified="2017-08-30" version="1">MTEEQKEKDYDSSKITVLEGLEAVRKRPAMYIGSTGLPGLHHLVYEVVDNSVDEILAGGATTITVTIKDDMTCSIQDDGRGIPVDLMKNAKDAKLRNKSALEVVMTVLHAGGKFDSGAYKVSGGLHGVGVSCVNALSETMEVEVRRNGHVYFQRYHRGKPEEAVKIIGDTQEHGTKVTFHADKEIFGELAFSTETIGNRLRELAFLNAGVKIIYTDERKEDNQTVTFHFEGGIAQFVKYLNTNKTVINPEPIYLTKEVGDNYISFAIQYNESYSENVFSFVNNIHTVEGGTHLSGFRSSLTRIINEYIKNNNISKHKDVSVTGDDIKEGLTAVLSVKIPHPQFEGQTKTKLGNSEVEGIVRSVVSDTLATFFEENPKTARAICEKCVGAAVAREAARKARDLTRRKGALEGGGLPGKLADCQERDSSKCELFLVEGDSAGGSAKQGRDRVFQAILPLRGKILNVEKAPLVKILSSDTVRDLIAAVGTGVGEGEGGFDISKLRYHKIILMADADVDGQHISTLLLTFFYRQLKPLIEGGHIYLAQPPLYKVKKGKVEQYLQTEEQMQQWLMKEGLATVTVTDMKKNEALSAEQLRDLLKVLRDVEDILAKLEVKNITLSDFMAFLSEGKVPVYRIPLKSGGFRYFYAEQEYRDYENQYMQEKREELAADGVDVDAVSNDSLIPEHQSLFEFGKLLADEKKMETFGFTFAQYPVIESEKDRVNPLFKVNNGKTDALVYSLAELLHAVKEAASAGATIQRYKGLGEMNPEQLWETTMDPAKRKLIQVKINDAADTEQAFTMLMGDRVEPRRDFIQSHALEVKNLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGX5</accession>
    <name>A0A1Y4DGX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-aspartate oxidase</fullName>
            <ecNumber evidence="4">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_03540</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + O2 = H2O2 + iminosuccinate</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:25877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56929">
        <property type="protein sequence ID" value="OUO56929"/>
        <property type="gene ID" value="B5F75_03540"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044318">
        <property type="term" value="F:L-aspartate:fumarate oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="PTHR42716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="10">
        <location>
            <begin position="7"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="11">
        <location>
            <begin position="438"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="519" mass="56878" checksum="47805770C6DA3CC8" modified="2017-08-30" version="1">MKVLHTDCLVIGGGIAGCVYAHQAAKKGLKTMLLCCGDMPEANSDLAQGGIVYEPNLNMDDLLADVKMATAGMCNEKAVKELSAAGCKAVQEVFLTDLSVNFDRDAQHQLRFTREGAHRKNRIIYSKDTTGHAMLAAIQQAVRKNPLVTVREYASAIDLLTLSHSSPDPMDRYYPLTVFGAYVLDNKTGEVFAVTAKKTVLATGGVGQVYRHTTNAAHAYGHGVAMAYRVGARVMNMEFVQFHPTVFAKGKSFLLSEALRGEGAILRNCNGEAFMPKYHPLKDLAPRDIVARAIEEERLKTSHDCVYLDTTANPAEETKERFPAIYKKCLEEGFDMTKVPVPVVPAAHYFCGGVYATPQGRTNIANLNAIGETACTGYHGANRLASTSLLEAVAMGYLCAEADAKDIASGSFHIPDPKPWVVPEEKPDLNLVKQDLATLRSTMWNYVGLIRSRKHLGRAEKILRHLHNEIDAFYKGTALCQELLDLRNGTQTALLITYAALKNRHSVGCHYLSDEKKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGZ3</accession>
    <name>A0A1Y4DGZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56198">
        <property type="protein sequence ID" value="OUO56198"/>
        <property type="gene ID" value="B5F75_06160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012892786" description="PpiC domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="217"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="44772" checksum="A2AC03CEFEABD34B" modified="2017-08-30" version="1">MKKANKLFLAVLLAALGVNGQAKVMESSVATVNGRPILSSEYDTYLDGVIEQYELAAPQFLQQPYAKDILGREVLKELISKELLYQAAEEEKIQVKDSEVDAGLNEIKSRFIVDETTGKPDPKGADKRFTEALKKQGMSLKTYTKKLSQDVAVRKLMEEKLKATVKPVEEADAKALYDDVEAVMKNKTKKIKELEKEDPARLKEAQAIAAKLKQLTGEQVRIGHIYLAVTKDMKPADVKKKEELAKQIKKEIDNGMDFSEAVKKYTEDKNALASGGDMILLKGVAPKAIDEKAFSLAVGKVSDPIKSDVGFHIIKIKEKRAERSISYEDIAKDLAQYLAQQRVQLAMAQYIEELYNKADVKVTIEFESDALLQDQAADAKAAPEKSAAKDAKADAKTAKEDSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH01</accession>
    <name>A0A1Y4DH01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_06210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56208">
        <property type="protein sequence ID" value="OUO56208"/>
        <property type="gene ID" value="B5F75_06210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="273" mass="28231" checksum="F2DAA5B03FDE992D" modified="2017-08-30" version="1">MIAEFLSYGFVQRGLVAGTLVAASCALLGVFLVLKRLSLIGDGMSHVCLTGVAAALLLSANPVYVSVPVVAAASLGIMKLTQKFKIYGDAAIGIVSAAGLSVGLLITALAGGFNTDLLGYLFGSILTVSKDEAVLCALLLAAVLAGLFFFYRDLTSACFDEPFARTRGIAVQAVNTGLVVITSVAVVLAFKVVGIFLISALLIIPPVAALLVSRTFKQVLWLAACFGVGSVWAGVYLSFVFNIPSGATIILVNLLVLACAYGWARMGGTSNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH11</accession>
    <name>A0A1Y4DH11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56218">
        <property type="protein sequence ID" value="OUO56218"/>
        <property type="gene ID" value="B5F75_06260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013051147" evidence="1">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="249" mass="26250" checksum="6965FE126E68F3C1" modified="2017-08-30" version="1">MRVFLTPFLLLAFLTLPLAAQNNHVLIAEQNAPAVVAINVVKNDGSTFTGTGFVLTPDGLIATSRHVAENALYMNITFNNGAVSGEAVSVAAAGNVDLALLKINARNLPYVTLGNSDTVLPGQNITVIGNPRRLQNTISSGLISQVRKKSDGVIWHQISAPISPSSSGSPVFNAQGEVISVAFASYKGEGNQNLNFAVPSNYLTELATAAGYVLPGAKAGAAPSEEATNPFIAHLQKSWQILKRLFQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH33</accession>
    <name>A0A1Y4DH33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ORF">B5F75_06365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56238">
        <property type="protein sequence ID" value="OUO56238"/>
        <property type="gene ID" value="B5F75_06365"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="214" mass="22723" checksum="9ECEABABD9794DEB" modified="2017-08-30" version="1">MNPAKLIDHTLLKPNATRADIHRLCEEARQYGFFSVCINPVWVSYAKELLKGSDVKVCTVIGFPLGANTTAVKVYETQDALKNGADEVDMVINIGALKAQDYDTVLQDIQAVRQASLGHVLKVIIETSQLTDEEKVKACEISAQAKADFVKTSTGFTGGGATAPDVALMRKSVPPSVQVKASGGVRTRADFDAMVAAGATRIGASSGVKIIEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI01</accession>
    <name>A0A1Y4DI01_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56568">
        <property type="protein sequence ID" value="OUO56568"/>
        <property type="gene ID" value="B5F75_05080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="8">
        <location>
            <begin position="134"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Transket_pyr" evidence="9">
        <location>
            <begin position="432"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="783" mass="85009" checksum="6D11B885EE002994" modified="2017-08-30" version="1">MSRTFEWGKKRGVFVDVTDYLDNPKYQISKEDAAGLERLDTVYRALVSLLYNYVPTSGHPGGSISSGRFVEHLLYKDMAYDLAHPLQDEADIISYAAGHKALGLYALWALRNECARIAAPQLLAQDEKHQLRLEDLLGFRHNTVQGTPLFKKFHVKALGGHPEPLVPFVRTSTGASGVGDGSAVGLALAAADAYGENCPQVHIVEGEGGMTAGRVSEAAAMAATAQLKNAVFHIDWNEASIESERVTADGEHPGDYVQWNPMEFFYMHDFNVIRVPNGHDFNQIHIAHQLAAELSNHQPTAIVYRTVKGWHYGIEGKASHGSGHKFASEGFYQSLAEFEKTFGVSFPRFEGDKTAENIEKYYWNSLLTVRQALEADKQTAAYAAACLQEASARLAAHARTVRAGLGNSKDLYRRFSPEQVPAEFVFEVGASYTTRGVLGKVLAYLNKQTNGTILTASADLYGSTGAAEISKDFPAGNFNTLSNPLSRRLSAGGICEDGMAALCTGISAFGKHVGVASSYGAFLAFEHVAARLHAIGVQAAREAGADPNTFIMFNGHASLPTGEDGPTHADPQALQLLQDNFPKGSCITITPLEVDEIWPLTVKALSMRPAVFAPFVVRPSYKFMDRAALGAEPAAKAVNGVYYLRRAKGTAEGTVLVQGAGVGRIVVEKLLPRLNKEGPDVNVLYITSRELFEALPQEEQNKILPPQLFQTAMGITDFTLPTLDCWINSLAGRRHTLYPHRDGRFLASASAEKVYAEAGLDGEHLFAAVCAYVQDLKGAAAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI53</accession>
    <name>A0A1Y4DI53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57339">
        <property type="protein sequence ID" value="OUO57339"/>
        <property type="gene ID" value="B5F75_00765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="186" mass="21128" checksum="0C8524367C8FB0FF" modified="2017-08-30" version="1">MKKKFSWKRFLVLLVLLAVAVGAALPHYLWTVERAKAGGAEAVLINLVSAENLYFLKHNTYTDDWRQLERYLSKIAQEQGAFAPAPEVGEERFFAFSAQDLEAAEDGFSFGIELSQDRASGKIYTVRDTGLFDYMLEDSFPQPAFRCEPDGGWISRWFCRKFTAYVEPLLMRKPAEAQEDKPQGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI76</accession>
    <name>A0A1Y4DI76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56648">
        <property type="protein sequence ID" value="OUO56648"/>
        <property type="gene ID" value="B5F75_05510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="137" mass="14974" checksum="CDBDE93C63FE720F" modified="2017-08-30" version="1">MFTFKKSKKELDITDAINRKKATITIGGQPVVIEAFKLSKALELINIFGKMPDLIKLATADLPAFNRLLLANLPQVLAFCVPNAKDINADDITLTEFADLILAVWAVNDMERIVSNFTTAVQSIPKATQVLASSPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI85</accession>
    <name>A0A1Y4DI85_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NDP-hexose 4-ketoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00990</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57379">
        <property type="protein sequence ID" value="OUO57379"/>
        <property type="gene ID" value="B5F75_00990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="7">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="842" mass="93783" checksum="3DF7F2B443483666" modified="2017-08-30" version="1">MAKRFTENAQKIILIAQEEAKRLNHDYVGTEHILLGLSAIEGTVSNKILTGLGVTFRKVRLEIEKMVGIGDTIMLLGEIPFTPRAKKVLEFSVEESQMLGSDHIGTEHILLGLIREEEGMAGRILENLGLNLDAVRDAVLNFIGDAAPGDLNEDVPDMPQEINLNSAPRREREPLEKKKTKTPTLDEYTRDLTKLAAKNQLDPVIGREEEIERLVQILARRTKNNPVLIGEPGVGKTAIVEGLAQKMARGEISDVLCNKRLLALDLASVIAGTKYRGEFEQRLKNIIDELASAKDAIIFIDELHTIIGAGAAEGSIDASNMLKPALARGEVQCIGATTFDEYRKYIEADTALERRFQPVVADPPDVDETITILKGIRSKYEQHHKVKYTDGAIRAAAAIADRYITDRAMPDKAIDLFDEAGARARLKNAVFPPEIKQKQMEYNQAVQEKDEALSKKEFEKAAAAKDTEDRLKAYVEHLKQQWHEKHDKEVPQVTEEDIALVASKWTGIPVTRLTQSETEKILHMEEHLHERIIGQDDAVKAVSLAIRRNRTGLGNPHRPIGGFLFLGPTGVGKTELAKSLATFLFGDEDAMIRLDMSEYMEKFAVSRLIGAPPGYVGYEEGGQLTEAVRRRPYSVVVLDELEKAHPDIYNILLQVLDEGSLSDNLGHKVSFKNCVIIMTSNVGAREITNKGNTLGFAAHQSEEQQYQDMRKNVMDEVKKTFNPEFINRIDEIVVFHSLSKENIGQILDLALKDVDAKLADKELSLKLTPKAKDFLVEKGFDVKFGARPLLRTLQRELEDPLAENILVSRYPAHTEILVDLDKDAGKLTFSGAAVKEKNAVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIA0</accession>
    <name>A0A1Y4DIA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphate starvation-inducible protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_07105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56040">
        <property type="protein sequence ID" value="OUO56040"/>
        <property type="gene ID" value="B5F75_07105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="100"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="314" mass="35106" checksum="ECE3C4D16ED85734" modified="2017-08-30" version="1">MIKTLKLKNQEEILIALGIQDRKLRALEKNFKVTVFVKYDEDGDGALLSVKGTNSRVDKALAKLQKDLALNAEKRPLDLVKDTVPFANNVVFRPEHARPVEARSENQKKYIEAVFANDLVISSGPAGTGKTFLACACALRALELGLTERIVVTRPIVEAGEKLGFLPGDIEEKVDPYLRPIYDAFYAMLGMERFNSLKYNNILEIVPLAYMRGRTLEKAFIILDEAQNTLPAQMKMFLTRMGIGSKMIVNGDLSQIDLPNKKESGLLQASEVLGKLKNVAFIQFTGEDVVRHPLVKDIVAAYDKWEKKHTGKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIB5</accession>
    <name>A0A1Y4DIB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PTA_PTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57399">
        <property type="protein sequence ID" value="OUO57399"/>
        <property type="gene ID" value="B5F75_01095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012147">
        <property type="entry name" value="P_Ac_Bu_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000428">
        <property type="entry name" value="P_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTA_PTB" evidence="2">
        <location>
            <begin position="83"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="305" mass="32699" checksum="6DD2A76B62102B08" modified="2017-08-30" version="1">MKFKSFADLINQVKGKSNRVVVPGANNKEALQAIKMADENGLISHGILIGPLAAVKETVAKVGLDESKFEFIDCEDVPTMCKLAVDQILAGKGDFLIKGLVDTKYYMKAILNKEAHLVPEGALLSHFVLFSTPKYKKPFAVTDSAVVIAPTLEQKVKIIQNAVNTMHKLGLEHPKVACVCPVEKVNEKIPSTVEAAALAQLNAEGKITGCTVEGPYDLYISLSAEKAAEKGITGKTVAGDADILMLPDLDAANPLYKALTFFGDQMEAAAVLVGPKIPVILPSRADDPKVKLNAIALCSYLKDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIL2</accession>
    <name>A0A1Y4DIL2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotin_lipoyl_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57509">
        <property type="protein sequence ID" value="OUO57509"/>
        <property type="gene ID" value="B5F75_01680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012757032" description="Biotin_lipoyl_2 domain-containing protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="5">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="474"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="503" mass="53500" checksum="D0F79B8E2AA3F436" modified="2017-08-30" version="1">MNKKLFTPAVLAAVFVSVAFFCGCKKAENTASMPAPVVNAITVVQKDLPWDIEYPAQVAGSLEIQIRAQVGGILQARLYNEGEYVTAGTQLFQIDDKEYKVALEKAQGTLAQAKAEERRTQRTYARMKRLRADNAVSQQDYDNALSAYETAQANVKVAQAGVGEAEINLGYTKVTAPISGIAGKEAQSVGSLISPTGESGLLTNMVQINPLYVNFSMPSRQFEKLSAGFISGQIAIGTEDQQDKLNAAQYRKTAAADAPIYVEVLLNNGKVYPEKGKIVFFDSTENTQTSSLAMKAEVANPNNSRALMPGQFVRVKLVGATYKNAILIPSSAVLNTAQGMMTYVIDANNTVVARPIQAQLQEDMYIVTDGLKAGERIMNGGLVKVRPGQQVQVQMQNFDTQAPAEQEAALAQDGRSTAVLEEEIEASEASDTQALPQEQPAPAAENAAQPKVAQPAAQTAEQPAPAAAETAQPAANDTVPQPAASSEAASQTAPQPAESSDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIN5</accession>
    <name>A0A1Y4DIN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56180">
        <property type="protein sequence ID" value="OUO56180"/>
        <property type="gene ID" value="B5F75_06070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="431" mass="49149" checksum="BA2887E0FACB682B" modified="2017-08-30" version="1">MTVQAAEEYVLGVLPKLGVNKRRELVRLVYEIAKRDGAPFSEILPAQKNLNFESAKKQLLARRYPVNFKTAAKDRFYLPKLELSPALQADLTPRPFYPKTVYIETSVQDSELAARVRAAFPNAQFKETDGKTQVGSPNFSRRLDTLLIHREKYDFLKPCPCSCAAACCGYNLINLGFGCRFECEYCFLQQYQNLHAVLLPANLDEFLNKIDGASFRKGPFDRPRIGSGEFTDSLVFDDLTRYSQKLVPFFRARPQLQFEFKTKSVNIGGLLEAGGCENVVVSWSVNSAKITDTAEHFTPGLSARLAAACEVARAGYRLGFHFDPVVIYDGWQQDYARTVEQMADTLPKDKVAWISVGTLRFSRELKKMIENRFPQNTILDGEFLLDFDGKMRYGDSQRKEVYQFLLPLLRKVFPHTHVYLCMEDPRLVQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIX0</accession>
    <name>A0A1Y4DIX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56888">
        <property type="protein sequence ID" value="OUO56888"/>
        <property type="gene ID" value="B5F75_03325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012531333" evidence="1">
        <location>
            <begin position="21"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="172" mass="18582" checksum="297071F347C18F6B" modified="2017-08-30" version="1">MKKLALIMALFVAAAMPAAAEAGNLKLSLWDEIAVAVPNNIHDVKGVDLGIASKTSTVTGLQFDFLFAQTEYELNGVSMTWIINLANQVKGAQFGLLTKNDDLIGAQLGLVNLSMHSTTGLQWGFFNQAEYMNGLQLGFVNYAKTIDGLQIGLLNIAENGWFPAMVIVNGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIZ2</accession>
    <name>A0A1Y4DIZ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_06650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56290">
        <property type="protein sequence ID" value="OUO56290"/>
        <property type="gene ID" value="B5F75_06650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="406" mass="45748" checksum="B1A1CC74C4C786B9" modified="2017-08-30" version="1">MPKMTCSHFGQCGGCALLDLPYEEQVARKRAKLQQTLSEFWTGDIPVTVTDDPKNFRNKVELGFCHQVKWRPDYDKKDPANKTRPLEFENALGFKLKGRWDRAVDITECVLFNDKLIPLLNAIRAWAKAENLDYYDQRKHTGVLRHLMVREGKNTGEEIVVLFVTDDFNEKTFVQAVQSVLPQANIMAAVNTGLADTAAPESLRVLKGKDHIFEKIFLTDASGKTEREVVFQLSPQSFFQTNTLTAQKMYSRVRRVVKALAPKRIYDLYGGAGSFSLSCADLCEKSICVESVAPAIYNGIENANLNGVSNVQFFCSKVEDFVKQHPIERKDALIILDPPRGGMHPKAAKAVAESGVERVLYISCNPVTLAADLKILTPHYDILQVEAFDFFPHSEHIETFVQMKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJM8</accession>
    <name>A0A1Y4DJM8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">B5F75_04930</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56540">
        <property type="protein sequence ID" value="OUO56540"/>
        <property type="gene ID" value="B5F75_04930"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="114"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="237"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="249"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO56540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="386" mass="42344" checksum="A035C01CCD29FE48" modified="2017-08-30" version="1">MIKQGKCFFTSESVSKGHPDKVCDQISDAILDEILKKDKTARVACETYITRGLVIVGGEITTRTWVDVEQIARDVIKNIGYDDAKYGFNYKTCAVINVIGKQSPDISQGVDVGGAGDQGLMVGYAVDETLEYMPLSLVLSHEILKNLEKARRTKMLPYLGPDAKSQVTVEYQDGKPVRVDTIVVSTQHTEEILDRSGSKITEKSKKEIEAAAIIPAVKKWIDKDTKIYINPTGKFVIGGPQSDTGLTGRKIIVDTYGGRCPHGGGAFSGKDPTKVDRSAAYMARYIAKNIVAAKLAHECTVQIAYAIGREEPVGFYVDTDGTGVIPDEKLAQIARKLFPLTPRGIIEYFKLRNPIYLATASFGHFGRKEFPWEATDKVSALQKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJX5</accession>
    <name>A0A1Y4DJX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57228">
        <property type="protein sequence ID" value="OUO57228"/>
        <property type="gene ID" value="B5F75_00145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990362">
        <property type="term" value="F:butanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08187">
        <property type="entry name" value="BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044731">
        <property type="entry name" value="BDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43633">
        <property type="entry name" value="PTHR43633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="3">
        <location>
            <begin position="11"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="396" mass="43334" checksum="E4ACF334959EC181" modified="2017-08-30" version="1">MRMRDFTFCCPTEIIFGSHAEEKAGEAVVKHGGSRVLIVYGGQSAVKSGLLERVEKSLMMAGLTVKKLGGVQPNPTLSFARKGVLEAIPFQADFILAIGGGSVMDTAKAIAIGAANPQTDIWTYWLGKETVTKALPVGCIVTISASGSETSDSAVLTDDAHKDKRGLNTPFNRPCFALMNPELTFTLSPKQIACGVTDILMHTLDRYFTPMQGNELTDALAEALMRTVIYYGPKAVQNPHDYVSQSELMWAGSLSHNNLTGLGAEKEFAVHQLGHELSGRFGVAHGESLSAVWQAWAMYVYKEDPARFARYACNVWRLETVTDIDTAAREGIEATVRFFTSLGMPTNLRELLGRQLSFAELYELADRCSRGGTRTVSKFKPLAKEDMLRIYTTANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK24</accession>
    <name>A0A1Y4DK24_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56680">
        <property type="protein sequence ID" value="OUO56680"/>
        <property type="gene ID" value="B5F75_04640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="16886" checksum="12E48805BC8F7168" modified="2017-08-30" version="1">MQKGFTLIELLVVVLIIGILSAIALPQYETAVEKSRASEAFVNGNAILNSMNRAINERPNEYPTTRASLDIRLSGGEWNASATRYATEYFLYDLSNGNRLEITRRLGDNDQYTLRLYNNLSDTPDKKDCVSTGSSSADLCKSFRSSGYELAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK48</accession>
    <name>A0A1Y4DK48_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH dtxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_00585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57308">
        <property type="protein sequence ID" value="OUO57308"/>
        <property type="gene ID" value="B5F75_00585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="16200" checksum="89015EE924CC7F46" modified="2017-08-30" version="1">MKYGKIYTHKLPRGAEEHEMKLSPNMEDYLEAVSLCANSEGVARVSDIRDMLGVKTPSVTGAMKALAQGGYVRHQPYSGIELTVKGRRAAEDVKKRHAILSRFLTQVIGVSPKIADMDACKMEHAVSRETLEKLHDYLRKQTGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKF6</accession>
    <name>A0A1Y4DKF6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">B5F75_02750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56780">
        <property type="protein sequence ID" value="OUO56780"/>
        <property type="gene ID" value="B5F75_02750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="97" mass="10643" checksum="BA0D3D42DD91034A" modified="2017-08-30" version="1">MAEVKIKPLGDRVIVKPIERETMKGGIIIPDTAKEKPMEGEVLAVGPGKLNDKGERAPMDVKKGDRVLYGKYSGTEIKLDDEAYLIIHQDEILGILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKM4</accession>
    <name>A0A1Y4DKM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">B5F75_03115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56850">
        <property type="protein sequence ID" value="OUO56850"/>
        <property type="gene ID" value="B5F75_03115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="361" mass="39490" checksum="43B488E4D368831D" modified="2017-08-30" version="1">MLYYLSLFTGDISFLNIFSYITFRTGAAIVTSFLLTLLIGPKVVAKLRSYKIQQIEREYGPASHLSKSGTPTMGGILIFLSLVVSVLLWARWDSNYIWLLLFTTVTLGIAGVMDDYTKLVKKNPEGMKSSIKLAIQLFTAVVVVGYLALNPPNGNYTTSLIIPYMSKMFVDLSVFYFAFAMLVIVGSSNATNLTDGLDGLASGCMVFTAATYAIFAYLAGNVNFADYLKIIYVPGAGEITVFMGALIGACLGFLWFNAYPAQVFMGDTSSLFLGGVIGTAALCVKQELLLPIAGGIFVLETLSVMLQMGYFKLTHGKRLFKMAPIHHHFELLGVPEPKVIVRFWIVGAMLMLLALASLKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKP5</accession>
    <name>A0A1Y4DKP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphopentomutase</fullName>
            <ecNumber evidence="4">5.4.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Phosphodeoxyribomutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">deoB</name>
        <name evidence="6" type="ORF">B5F75_01625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphotransfer between the C1 and C5 carbon atoms of pentose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27658"/>
            <dbReference type="ChEBI" id="CHEBI:57259"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-ribose 1-phosphate = D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:18793"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="5.4.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 or 2 manganese ions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphopentomutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.7" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57498">
        <property type="protein sequence ID" value="OUO57498"/>
        <property type="gene ID" value="B5F75_01625"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008973">
        <property type="term" value="F:phosphopentomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043094">
        <property type="term" value="P:cellular metabolic compound salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16009">
        <property type="entry name" value="PPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00740">
        <property type="entry name" value="Phosphopentomut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010045">
        <property type="entry name" value="DeoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024052">
        <property type="entry name" value="Phosphopentomutase_DeoB_cap_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21110">
        <property type="entry name" value="PTHR21110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001491">
        <property type="entry name" value="Ppentomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143856">
        <property type="entry name" value="SSF143856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01696">
        <property type="entry name" value="deoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="5">
        <location>
            <begin position="6"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="402" mass="43536" checksum="DF6F6DEA8D9EABD4" modified="2017-08-30" version="1">MTRKGRAVILMMDSFGIGGAEDAAKFGDAGADTLGHIAAARGGLNVPNLAALGLFKAAEASTGKAPAAGAQTKASVSLPSKYGFMREISHGKDTSSGHWEMAGSPVQFEWGYFKPDYPSFPPELIEKICAEAGLPGILGDKAASGTAIIEELGEEHIKTGKPICYTSADSVFQIAAHEKHFGLERLYKVCEIAFKHVAPYNIARVIARPFEGEKKGEFKRTKNRHDYSVKPPMITVLDEIKNAGGEVISVGKISDIFAKQGITQAVKASGLEELWDVTLAQAKAAPDFSLVFTNFVDFDMTWGHRRDVEGYAKGLEYFDTRLPELAAQMQPGDVAFITADHGCDPTYKGTDHTREHVPVILFGPGIKPQFIGGRDTYADLGQTLADYFKLPPLRFGKSFLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKP6</accession>
    <name>A0A1Y4DKP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56870">
        <property type="protein sequence ID" value="OUO56870"/>
        <property type="gene ID" value="B5F75_03220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="163" mass="17645" checksum="15CB6D792E2581F8" modified="2017-08-30" version="1">MQQGFTLIELLVVVLIIGILSAVALPQYEKAVEKSRAAEALSLLKTIQNAAAVCELEKGESDTCTLDDLSIGLNSLDCVDGLECTGKYYFYNFDEGIRNPYVCPIRGGCTSYVIQLVGPSYGGTQARLNKRICIGRDDKGKSLCSSLGGKKLSSSTDETVWEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKU4</accession>
    <name>A0A1Y4DKU4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56920">
        <property type="protein sequence ID" value="OUO56920"/>
        <property type="gene ID" value="B5F75_03495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="111"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="278" mass="32368" checksum="2096D4BD12240315" modified="2017-08-30" version="1">MGEIRQAVANSGAKRKMTFCWIALLVLVIYLFWRFPNLRKTWYLPKRKGFVAFMYHHVGVLQDPQAEQYPFTMRPDMLERQILFLKANGYTPLSLEDLQNATRAGKSSVSKPVMLTFDDGYRDNYENLFPLLKKYNLPALIFLITDRIGSPEYLTWEQIYEMQQSGLVSFGSHSCSHRRLRSLSDEEIVQELTCSKQILEEKLGREITAFCYPYGAGGFDKRVRPQVFKAGYLFDFSTKKGINPWPWKGKSTLRRAFPRGGETMFDYYLQLTRGQSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL35</accession>
    <name>A0A1Y4DL35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57010">
        <property type="protein sequence ID" value="OUO57010"/>
        <property type="gene ID" value="B5F75_03960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="17472" checksum="736CE879E6562E51" modified="2017-08-30" version="1">MHKTHTGFTLIELLVVVLIIGILAAVAVPQYEKSVNRAKTTEAMTVLSYIEKEQTMAYLANNYIPNDIYFDIRDSYPMKYFQIGSMTGNQGAESFVLLSPTWGDRDITIVAYFEDGKGKWYCSGKCRKYFSSSDCQDSTYSVNALTIINAAACVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL95</accession>
    <name>A0A1Y4DL95_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56191">
        <property type="protein sequence ID" value="OUO56191"/>
        <property type="gene ID" value="B5F75_06125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="244" mass="28081" checksum="68C406EFA0D71EC8" modified="2017-08-30" version="1">MYSDVYELNYSKIKTYLECPVLYKLKYIEGKREGLVPASSLGVSIHRALEEYHRSSNDPSELLSYYDDCWLGAGYASAGEQMEWYLKGKKMLETYAQAEYERKTTVDSTEREFIFQEGQWTLRGKIDRIDKHPDGSWEVIDYKTGTDVDLSLPVTDSLQLGIYAVGARRAWNMQKGIATFYFVAFNQKMSAPFEAFDEAKILDTFIDIGKKIEVNDFEPNLQHCASCPFQTRCEHSCVKPEKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLB4</accession>
    <name>A0A1Y4DLB4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56211">
        <property type="protein sequence ID" value="OUO56211"/>
        <property type="gene ID" value="B5F75_06225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="153"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="300" mass="32735" checksum="22ABCE95462B45B8" modified="2017-08-30" version="1">MSYILALCLALCWGTAFLASKNIVESLPPYWGTFYRVLAGLCFFIVLYAVQRKNLKCPIKQLWRPWAIGLLLILLPFAAISWGQRFVAPTIGGIFNGTVPIWSFIAGAVLLKGEDRFTWRRAAGVTVGMIGLLIIMHPMISAAKLNASPMALYGCFAFLIMAWSYSLGNVLTKKIMVDSNAMTHEANTFHQYLFSAVVLLIISFLAEPVPAASAFTTKVVLSIISAGVFSSAVAFLLMVALIKRWGATRMASVTYFTPVVAMASDMIAFGRMPTGAELGGLLLIFASLVMIQKKVEPESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM66</accession>
    <name>A0A1Y4DM66_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57390">
        <property type="protein sequence ID" value="OUO57390"/>
        <property type="gene ID" value="B5F75_01045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="359" mass="39990" checksum="14B40791C2A14951" modified="2017-08-30" version="1">MILMDDLFKLMKAKNASDIHLTVGVPPVLRIQGRLYATQFEPLTKETAQTLIYSIMTDEQRQQFEEDLELDFSFGLKSLGRLRVNIYKQKGCVAAALRSIPNDFKSFEELNLPPVVYNIMKLNKGLVLVTGCTGSGKSTSLASMINYLNMNESNHIMTVEDPIEFVHPHKRSIVNQREVGADTHSFAAALKHFLRQDPDIILVGELRDRETMEACLTLAETGHLVFATLHTNDAVQSINRIIDVFPAEQQPQIRTQLSFVLEAILSQQLIPTLTGGRAMACEVLLANSAVRSLIRDGKAEQIISTMQTSVGMGMITMNQALGDLYIQKKISYQEALSHTSDPSGLKTYLQQKLGTSSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM91</accession>
    <name>A0A1Y4DM91_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57410">
        <property type="protein sequence ID" value="OUO57410"/>
        <property type="gene ID" value="B5F75_01150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="119" mass="13099" checksum="4188EAAE34F38229" modified="2017-08-30" version="1">MLKIALVDDSVILRSAIKNVLESSGFKVVFEAGGSAELFSKIENSGVELILLDIFFPTENGLDILAKLKKHMPQVKVLIVTGLRQDTILEEAQRLGADGVLYKPFDTDELLSAIQRVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMJ1</accession>
    <name>A0A1Y4DMJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57520">
        <property type="protein sequence ID" value="OUO57520"/>
        <property type="gene ID" value="B5F75_01740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011825364" evidence="1">
        <location>
            <begin position="31"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="34"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="311"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="498" mass="54056" checksum="72B3CF6B6B3DADFD" modified="2017-08-30" version="1">MKKGTVLFGEKMKKIFILLLSFFAALPLAAKTATIYHTSDTHGFFYPKNGQGGAAALAAVLAAGPKNYLLLDGGDFAEGTVETQRSNGLKAVSLMNRLGYDAATVGNHEFAFRDDGFDALLEAARFDVLAANLVPAAGEKLPKRVKPYQLYNVNGMKVAVIGLANRNPTKKSQKYKFIKPLAALEKALQEAEKQQPDAVVVLVHDSLADDRPGSPNYIGDIGRQFGGRVQVVLGGHAHKIFQNEWRGGILFAESGCHFQNVTKITLETDDKTGKITDIRSELIALNTAQTGEDKKMKAYAQSLREPGVDEVIGQTAAAFSKKSFIPTHQDDPVDNWVADATCRYTPADVCIHNTGGARVGLPKGDITRRDIIDLYPFDNTVVTATVSGAFLKKLVAGGVVPWNRLAYSGLTFSYKKTKKGKIKKLKIWVRGERLQDDKQYTLAVNSYVAGGGSEGKLFKTLPQGSIRPAGQLTMRQILEADFKNGPLTPPATGRVVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMN1</accession>
    <name>A0A1Y4DMN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56651">
        <property type="protein sequence ID" value="OUO56651"/>
        <property type="gene ID" value="B5F75_05525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="150" mass="16677" checksum="18031C720B10034D" modified="2017-08-30" version="1">MIKLTVKGLNELVRKLQEEERNAVLAMTKAHSKVAADAASKLKRGLSFRAGRSPKDKNYQNSPAGSLPYAHTLRLRDSIGYKILAQGRRVFSEVGSGAGASSVEYAKYLEGRNNDGIRPFLWAVKNDYNPEKINKKFWEYFKPLSGGSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMQ5</accession>
    <name>A0A1Y4DMQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56681">
        <property type="protein sequence ID" value="OUO56681"/>
        <property type="gene ID" value="B5F75_04775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="279" mass="31073" checksum="DDBF6E36789C3C58" modified="2017-08-30" version="1">MRRGAKPPGQPVACRRAVRTKRARRDVSIRFGKQGNYLMKKIAVLLTALVVIYLAADYHVQRMHQLGAKLVQDAYRGDLLAVKEDLEQGAPPEYELYLQDLSRGYGGVQFTVLQAAASSGNEDLINFLLNEGFYIDYPTPQGWTPLFIAVRDGQAEAAKLLIYRNAELNAQTDRGATALMMALTQKFPSEKAREDLLLYLLKRGANPNLQDTSGHTALYYAAVLQNEKAAALLYEYGAAPDEEEKAQIRKLLSGKKDAAAKKILRLLKRHPQPVSAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMS3</accession>
    <name>A0A1Y4DMS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmI</name>
        <name evidence="7" type="ORF">B5F75_02265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57620">
        <property type="protein sequence ID" value="OUO57620"/>
        <property type="gene ID" value="B5F75_02265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="68" mass="7695" checksum="28459BB8DD7E7261" modified="2017-08-30" version="1">MPKLKNHSGGKKRFRKTATGKFTHRKAGRKHLLTPVSASRKHETRKTGVITPESNKGKILEKYLPMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNB5</accession>
    <name>A0A1Y4DNB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">B5F75_03340</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56891">
        <property type="protein sequence ID" value="OUO56891"/>
        <property type="gene ID" value="B5F75_03340"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="19"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="143"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="245" mass="26557" checksum="702F63E6BA06C948" modified="2017-08-30" version="1">METCCPSKNCQPKKRVLLKLSGEALINEGHRGINPQALKEIAEEIADAYRCGNCELTIVLGGGNIWRGVRDGGGVIDRVNSDNMGMLATVINALALQSALEEAGVPTRVLTSINIYQLAEPFVRRKALRHLEKGRIVIFAGGTGNPFFTTDSAAALRASEINADVLLKATQVDGVYDSDPKKNPNAKLIHKITYKEAIARQLQFMDTAALALCLENKVPVQVFNLHTKGNIKKALCGEDVGTIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNK8</accession>
    <name>A0A1Y4DNK8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MgtE_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56991">
        <property type="protein sequence ID" value="OUO56991"/>
        <property type="gene ID" value="B5F75_03850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MgtE_N" evidence="1">
        <location>
            <begin position="19"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="249" mass="26864" checksum="4832223335DF9444" modified="2017-08-30" version="1">MNSPMHALAGVITEKFIAADPAAAARALETLATHEVLLLVSSLKAQTLVACLNPMNPAKAAAVLRRLPMRQASYVLAHLDVPQAARLMNEFSAPYRERMAAVLEPAFAELLKKASSYPPGSVGLLMTTDVVAVRTESKLSALIERLKNLPRKKLPAVCFVTGKDGELKGVIRTAELAFYTPASVCGSVMSPVAALHPEQDAQTARETFLKEQTDILPVTDGKNILLGFLAKQNLPPAADKKPFWKRLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DP82</accession>
    <name>A0A1Y4DP82_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57201">
        <property type="protein sequence ID" value="OUO57201"/>
        <property type="gene ID" value="B5F75_00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="356"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="499" mass="57935" checksum="706F09B40C8536F1" modified="2017-08-30" version="1">MFDKKSYTLYKFHKQLNQSFQNKRELLECALPALRNLFKLDRVYFFDWQQERALLSLKMMCKKEYCMDMQEDISVLNEPVFLKQLLQNGIAESTDLSYPAIYVLVKWERPSVELKSGEVHNFMQEKVGVLRLERFRKNRVFSEQEKELIKALGEEISHNLRNTEIDQAKNQRLNISTALNDLSTIFASSLRLNDGLELILKGVQKYFRFDRVRLYLTDSEGSKIKSVLGVDISGKVTQQDGKTLPAGEENLLKEVFDSMATYRANRSVIYIPLKVQRNKVGFLAFDNILSRRRIGYMDFISLQQFASQMALSIDNARLFERVQELSNYDELTKLPVRRYFNEKFAEEIYRSKRFDLTMSLIIMDIDWFKQINDGYGHQIGDWALKEVSRVIRTSLRQTDVPCRFGGDEMVIMLPRTNGEEAKIIAKRLKDRIGAITLPERYTEGKEVHLSISQGISSFPFDGQTPDVLLEKADKALYVVKQNGRGSFAVYREVADQVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ34</accession>
    <name>A0A1Y4DQ34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HEPN_LA2681 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57481">
        <property type="protein sequence ID" value="OUO57481"/>
        <property type="gene ID" value="B5F75_01540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040826">
        <property type="entry name" value="HEPN_LA2681"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18733">
        <property type="entry name" value="HEPN_LA2681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEPN_LA2681" evidence="1">
        <location>
            <begin position="277"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="528" mass="61950" checksum="FFAFA9EE5AADEEB6" modified="2017-08-30" version="1">MKRYLSPKDKERYADYLTINAKYYHLAKKIDAAEYTKNLEVLHQAIDECQEAINLSTDPLELSTLYYFKSNGLRGLKEKNSWNWRTAIEGQILLAMRNSIRYSLIVSHKIPKAELARRYTNLANATDFAGLFIEAGELYDRALYFQEDKGVALLNKGISLISYGNYVCNEDTAQIFMREAAFWLQEAFRIGEKDLREETVPIKQAKERYSRFLQVPQPVQFKNIEEKFSIEPEELKYRKWAAENRLFLNPLNDLCSEPIKLCVVEDCLMAPSFIFDDSSKRKYLPLWINQLKQEFIAARTLCFEGFSAPREHYSDHLTFLEAHPLLPGRIYSFNLEKIKWAFRSAYSLFDKIAVILTDMYAIEHTNKVYFRSFWYQNENFKQPLKPFFSSEPKTQNFNRHNLALRALFSIANDFSSKTEEWKDSLDEEMRDITAMRHNLEHNGLEVIETGESNLKERIITLQDLIDKTLYLLKKCRNAIMYLIFAINEESRKETEKDKHLRLPIHGLPYFVPEGLDFSLGKDSSSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQI3</accession>
    <name>A0A1Y4DQI3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_02320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57631">
        <property type="protein sequence ID" value="OUO57631"/>
        <property type="gene ID" value="B5F75_02320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="284" mass="31847" checksum="05D068922F64DCDB" modified="2017-08-30" version="1">MGLESRYSSLPLSKFVVVPVPFEKTVCYGHGTAKGPAAVIEASTQIELWDEETKTETWELGINTQPAVNCKGSTNTVFKNIDKTVRNLMQYKAIPFYIGGEHTVTQALAQPYIEKYKDLSILHFDAHADLRETFEGTPKSHACALYPASRQVPVVQVGIRSVASEEKQYCNAGKVTTFLMHENRDIKKLIPQVLKKLTDTVYITIDVDGFDPSVIPATGTPQPGGFMWYEALDLFREVIKHKKIVAVDVVEACQRKADVITEFNVSKLIYRLMGYLALKDQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9W3</accession>
    <name>A0A1Y4D9W3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">B5F75_07075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56034">
        <property type="protein sequence ID" value="OUO56034"/>
        <property type="gene ID" value="B5F75_07075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="360" mass="39502" checksum="81A79C448419593A" modified="2017-08-30" version="1">MEKETILIGLSGGVDSAAAAVLLKQQGYRVIGATMLIWDPSLPVPNGPYQKNACLSPEKEDISEIENLAKKLDIEFLAVDCRQQYRQTVLDNFRQEYACGRTPNPCVWCNSLIKFGVLPAAAKAQGIAFDKFATGHYARVEYDPAAGKYVLKRAKDLSRDQSYFLHRLTQEQLSRVLFPLGEKTKPEIREVARQAGLAVADKEDSQDFYCGNYNDLLNFPNKPGDIVTLDGKKVARHNGIWGYTIGKRKGLGVSGFKTPMYVVRIDAPKNQVVIGPKEALYTSTLQADHVSWVAGEVPAENFSCEIKIRNLHVPARARVHVLGDGSFTAQFAEPQLSVTAGQSAVLYADGDVVLGGGIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA75</accession>
    <name>A0A1Y4DA75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56157">
        <property type="protein sequence ID" value="OUO56157"/>
        <property type="gene ID" value="B5F75_05940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="160" mass="18171" checksum="5EC99D407BBFF212" modified="2017-08-30" version="1">MSTEKEFLEKVSALDFDPARQAQQRVWARVLHQSAPRRSLKPLAWGICTGLLLMLGGIAGMYWSDSLQDKDYPQSTAFWQRAQCKKADGRVLVSTELECHGEKCSCTKTMTICDEHPVTRVTRKNCKTPPSDFDPQDPWSLWNDDAAKQTKDLAFCQNQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA86</accession>
    <name>A0A1Y4DA86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56133">
        <property type="protein sequence ID" value="OUO56133"/>
        <property type="gene ID" value="B5F75_05795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="34018" checksum="FC9DCA45F51A2494" modified="2017-08-30" version="1">MAENKKIVFEGYSRRLDVFAADELADFSRAIVQKMIKDGKITVNGKKVKPSWPLTPGEVVEIEMPHPQAKTDLNDLIIHDAKDFFVLIKPAGMLVHPQSPVWEEHPEAVFSSEETLVSVILANPPKGFDLSTPRAGLVHRLDRETSGVMLVAKNPEFQAEMVALFANREVHKTYHSIACGEVPDDEGTIDVPIGRVAGGKIKASDVGREAVTDYKVLERKNGFTYIELYPRTGRTNQLRVHLSWLGYPVLGDWLYRGATAERLMLHARRIEFKHPFTGKALKFEAPVPPDFKAAWKRVTTPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAD4</accession>
    <name>A0A1Y4DAD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56194">
        <property type="protein sequence ID" value="OUO56194"/>
        <property type="gene ID" value="B5F75_06140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="182"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="383" mass="42057" checksum="B390F0BF495B52C1" modified="2017-08-30" version="1">MTKKRISQSKGERCRVFSCPQHKQQPAPQEAAQGLLGALAPEDLKSIQKHGVEGYDVVAVVDAHTRQATVVSNISGRLSLADITDNLTAYSRPLKQALEGHIQHYEWGLEKAGKHCFYQTTLIPLSGENNQIDRILFLTRDITYWGGVYRGGEMLREGSAPRTFSQILLAARETEKKEISKALHDEIGSAVVILTALLSLVKASVKEGNRKQALEDIAKLDAQIKNSVDRVKNIIVSLRPPSLENDGALGGSVQELLENISGYVHIPYTFDYDPATKENGISDSVKILLYRIVQEALNNIVKHARASKIYVLLARQGDQIRLVVEDDGIGFKPVKQRSIRKVGLLAMQDSVRLLGGTISIKSTPGKGTRIEVACPCVVYGGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAP8</accession>
    <name>A0A1Y4DAP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_06610</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56283">
        <property type="protein sequence ID" value="OUO56283"/>
        <property type="gene ID" value="B5F75_06610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="16"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="437" mass="48887" checksum="3AE8B0A072A1FFEF" modified="2017-08-30" version="1">MTSEVATVKTEKQPTGLYILFLTEMWERFSYYAMRGILVLYLIKVMQFSESHASKVYGAVTSLIYLSPLLGGYIADRFWGQRRAIIVGGILIALGQFAIASNPTLSFLYTGLFLLILGNGLFKPNISTIVGELYEKNDSRRDAGFTIFYMGINLGAFICNFVAGTLAEKVGFGWGFATAGFGMILGLGIFIWAKDKYLQGQGKKPKKLTKEEKLEHPTNPLTTEEKQRIAVIFIMAFFSIFFWSAFEQAGASLTIFAEKFTDRFIFGWEMPTSWFQSVNPMFIILLAPVFSKLWLKLAKKGLEPSTPAKFVWAFMSLAFGFLILVAASYVIQTTGAKVGIFWLVFAYMFHTMGELCLSPVGLSLVTKLAPLRFASLLMGTWFLANALANFTAGFYSGYFGHISNVQFFTWLVIMPVCGGLILLSIKKFVIKWMNGIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAW9</accession>
    <name>A0A1Y4DAW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56353">
        <property type="protein sequence ID" value="OUO56353"/>
        <property type="gene ID" value="B5F75_06990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012847883" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="13173" checksum="5C12E55802DD676D" modified="2017-08-30" version="1">MKNMKKTYLMIFAAALLAACSSAPQKVGINAMPVKLNKAITAADKTCQTDADCVAVKKGCCECAGYEAVNVKAAEKVQKVWNKECQMAPCTREMCYVQITPKCENNVCTGELKPMDSYFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAX1</accession>
    <name>A0A1Y4DAX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">B5F75_06955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56347">
        <property type="protein sequence ID" value="OUO56347"/>
        <property type="gene ID" value="B5F75_06955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="94" mass="10606" checksum="A087788A16B95A9E" modified="2017-08-30" version="1">MGRSTKKGPYVDLNLLEKVQAMNASNEKKPIKTWARACTIVPEFVGHTFLVHNGRKFLPIYVSERMVGYKLGEFSFTRLFKGHGGMTKDSTALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB62</accession>
    <name>A0A1Y4DB62_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56296">
        <property type="protein sequence ID" value="OUO56296"/>
        <property type="gene ID" value="B5F75_06685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17328">
        <property type="entry name" value="MFS_spinster_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="PTHR23505"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="402" mass="44016" checksum="4B962AA3DA980025" modified="2017-08-30" version="1">MNTKHLFWILFLLNLFNYIDRQVLYSVFPLLQTDLHLSDWQLGTLASVFMLVYMCYAPVVGYFADRSPRQKWIGASALIWSAATLACATARNYFSLLFTRGLIGVGEAGFTTIAQPFLAENYPKKKRATILAVFGLAMPAGSALGYMWGGAIGLHWGWRTAFLLAGVPGLVLGILSLTHLKDIRRAQQTAAEKPSRHDYKALFQNKPFLFICLAHAMITFIIGGLSAWMPTYLHRYLQMDVAQAGTWFGALVICCGAAGTYAGGKLADKWLEFSPKAYFWVIGVSFLALLPPAWLGIQTNRPALALGCFGLAIICLFLPTGPIAAALVASTRNKVHAMAFAVNIFIIHALGDALSPMLLGHASDLWNLKIAVLLCSLAAVPGLVFTWMAASFERRLPEPPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB83</accession>
    <name>A0A1Y4DB83_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">B5F75_06845</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56326">
        <property type="protein sequence ID" value="OUO56326"/>
        <property type="gene ID" value="B5F75_06845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="23"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="263"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="332" mass="36310" checksum="552FCBB1AD446EE2" modified="2017-08-30" version="1">MAFNELVLPQKIQLEEKTASDSYGKFIAEPYESGYGHTVGNSLRRILLSGMEGAAVTAVKIAGAVHEFSTIPNVREDVINILLNLKRLRVKMEGKNRDCLQLHVAKPGVITAADIEESDGVEIVNKDLTLATLEVGGSLDMEIEISRGKGYVPAEDLAKIQRPAGFIPVDALFSPIVKVHYDVEPARVGQKTDYDRLILEITTDGTLLPARALHRAAVLLSNSLHIFTIEGEDDCVATTSDEAVEEPVSMTGSVAGANVNSKLDELLNQSIEFIELSSRSINCLKSENINTVRDLVKMSEDDLKMIKNFGAKSMDEIKERLAEMNLSLGMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB99</accession>
    <name>A0A1Y4DB99_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glycero-beta-D-manno-heptose 1-phosphate + H(+) = ADP-D-glycero-beta-D-manno-heptose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59967"/>
            <dbReference type="ChEBI" id="CHEBI:61593"/>
            <dbReference type="EC" id="2.7.7.70"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.70" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56135">
        <property type="protein sequence ID" value="OUO56135"/>
        <property type="gene ID" value="B5F75_05810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011914">
        <property type="entry name" value="RfaE_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02199">
        <property type="entry name" value="rfaE_dom_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="6">
        <location>
            <begin position="30"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="154" mass="16958" checksum="1DCD99D0D44615E0" modified="2017-08-30" version="1">MKAKNKILGPRALKKFVEEARKNGRKIVFTNGCFDILHAGHVSVLEFARSKGDVLVVGLNSDASVRRLKGPSRPVNTQADRALVLGGLESVSAVSIFEQDTPYELIKLVRPDVLVKGGDYKTDEIVGREFAKKVVRFPLLKGRSTTNIIKKVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBC6</accession>
    <name>A0A1Y4DBC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gldA</name>
        <name evidence="8" type="ORF">B5F75_05985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56165">
        <property type="protein sequence ID" value="OUO56165"/>
        <property type="gene ID" value="B5F75_05985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016205">
        <property type="entry name" value="Glycerol_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43616">
        <property type="entry name" value="PTHR43616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000112">
        <property type="entry name" value="Glycerol_dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Fe-ADH" evidence="7">
        <location>
            <begin position="8"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000112-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="361" mass="37955" checksum="FC77BB687A06B258" modified="2017-08-30" version="1">MERIIFSPMKYVQGPGAWQRLAEFAAGLGATGAYAVAGPHVLKHNWEPIEKSFQARHLPLTAHAFAGECSMTEIKRIVNEIHEKNCGVVIGIGGGKALDTAKAAAFYAKLPVIIAPSLASTDAPCSALSVIYTEEGAFESYLILRNNPDVVLVDTSVIAQAPVRMLVAGMGDALATYYEARACFASGKKTTAGGKSSLSALAIARACRDSLFKNGLRAKLAAEAKTVSAALDDIVETNTYMSGVGFESGGLAAAHAIHNGLTVLPQTHPFMHGEKVAFGLLVQLALENAPQVEFNEVLSFCRRVGLPTNLAALGLENVSDDELQQVAAASCAEGETMHNMPFAVTPQAVFAALKIADKLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBG7</accession>
    <name>A0A1Y4DBG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56215">
        <property type="protein sequence ID" value="OUO56215"/>
        <property type="gene ID" value="B5F75_06245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037090">
        <property type="entry name" value="57_glycoside_trans_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015293">
        <property type="entry name" value="BE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040042">
        <property type="entry name" value="Branching_enz_MT3115-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028995">
        <property type="entry name" value="Glyco_hydro_57/38_cen_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41695">
        <property type="entry name" value="PTHR41695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09210">
        <property type="entry name" value="DUF1957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88688">
        <property type="entry name" value="SSF88688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="3">
        <location>
            <begin position="9"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1957" evidence="4">
        <location>
            <begin position="428"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="540" mass="63753" checksum="843FEAEFA338A6B8" modified="2017-08-30" version="1">MGEEKGYLALVLHAHLPFIKHPEYPDFLEEDWFYEAMVETYIPLLNVFENLTEEGTDFRLTMSLTPPLCNMMEDPLLISRFRHYLNQRVELSQKELNRTQGTEFEGVARMYFNKFRRYQDLFENRYHGHVLEGFKKFQDMGKLEIITCCATHGYLPLMVHKESVNAQIKVAANDYRSRFGRSPRGIWLAECAYNPGDDKFLRDEGIRFFFTESHGLLHGTPRPKYGIYAPVYCPQTGVAAFARDMESAQQVWSAESGYPGDPRYREFYRDLGYDLDYDYIKPYLHSDGVRRNIGMKYHKITGKVALNQKQAYNPHEAREVAAMHAGNFMFNRQKQIEYLSTLLDRKPLVVSMYDAELYGHWWYEGIDFLEYLFKKIYYDQKDIKLVTPSEYLEMYPENQVVQPSMSSWGDKGYHDVWLNSGNDWIYRHLIKTSERMMELANKFPHADGLLRRALNQLARELMLMQSSDWAFLMTTGTAKEYSTKRTKDHVKRFNELYEQIQGNRIDEGFVYDLEQKDSIFQQMDYNVYSSAAKEAVLRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBH0</accession>
    <name>A0A1Y4DBH0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56514">
        <property type="protein sequence ID" value="OUO56514"/>
        <property type="gene ID" value="B5F75_04790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="326" mass="35028" checksum="484248AFEAAB5259" modified="2017-08-30" version="1">MAEYKDYYKILGVNKNATDAEIKKAFKTMARKYHPDLHPESEKAKMTEKFKDINEAYTVLSDKQKRTIYDQVGEQGYQDYTRGGGASSRARSSSSYGGGNPYQQYQQYSYGGNGGGFSGFAGNSGAEAFSGGDFSDFFQSIFGGMGGGGFGGFGQNFGRTAASGQAAGDVEAELALNMEDAHRGGNMQMTLPNGRTVTVKLPAGVSEGKKIKLKGMGNPTRRGNGDLYLIVKIRPHAMFRLEGEDLHVPVIIMPWTAALGGTIFVPTLDGPVKVKVPAGTHNGKKLKLSGKGLSARGSLYVTLTIDVPRTLSKEQKDLFTKLAQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBI1</accession>
    <name>A0A1Y4DBI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_04845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56524">
        <property type="protein sequence ID" value="OUO56524"/>
        <property type="gene ID" value="B5F75_04845"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="5"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="324" mass="35897" checksum="064ABD7ED5C29A7F" modified="2017-08-30" version="1">MKNILVIGGAGYIGSHTVKMLAQKGYNPVVFDNLSKGHREAVANYPFELGDLGDKARLAEVFKKHQIDAVMHFAAFIEVGESVKEPSKYYHNNVAKVLNLLDAMVEHGIKYFVFSSTAATFGEPVKEKIDETHPQNPINPYGNTKLMVEKMLADFDTAYGLKATALRYFNASGADDSGDIGESHTPETHLIPIVLQAAAGKRPCIKMFGNDYPTPDGTCIRDYVHVNDLARAHILALEKMFKDNVSERFNLGSGNGFSVAELVKEAKRITGVDFKVEVAPRRAGDPAVLVADSAKAQKVLGWKPEYNLTRIIETAWNWEQHRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBI3</accession>
    <name>A0A1Y4DBI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56503">
        <property type="protein sequence ID" value="OUO56503"/>
        <property type="gene ID" value="B5F75_04730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="20491" checksum="7CBFE5628489946B" modified="2017-08-30" version="1">MELMDVIKARRSVRKYQDKPVEREKINACLEAARLAPSACNSQPWHYIVIDDPKVKEAFCKEAFSGVYAMTKFAEKAPVLIAAVSDKGSFTSRLGNFFRRTEFYLVDQGISGEHLVLRAQDLGLGTCWIGWLNSDKAEKFFHLPKGKKIEHLIALGYPAEEPAPRPRETLEHIVSYNEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBJ1</accession>
    <name>A0A1Y4DBJ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimO</name>
        <name evidence="10" type="ORF">B5F75_04810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56517">
        <property type="protein sequence ID" value="OUO56517"/>
        <property type="gene ID" value="B5F75_04810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="135"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="427" mass="48569" checksum="98268A2081EA3E1D" modified="2017-08-30" version="1">MKFYLISLGCPKNLTNSEEFSARLLAKGHKMVFSPEKADEIIINTCGFIASAVKEAKEEICYALDLKQKGIVKKVAVTGCLVERFKEQVEKEFPQLDTIFSIAAQEKVEDALKHRGTLLAPLPKKLWLPEYKMSLTAPHTAYLKVADGCNNRCAYCTIPFIRGNYRSKPMNEVLQEAKLMIENGVKEISLIAQDTTSYGIDLYGKPRLLELLEKLLKLKGLGRLRIMYGYPHRVTKEIARLIASTDKIFHYIDIPLQHIADPVLTRMNRHCDAAQIRRTLDMLKTEVPDISLRTNFIVGFPGETKKDFNELKKFVKEYEFDNMGVFEFFREKGTAAYGMEQIPARVKHERAHELEEVQSRVIDKINKRLVGTVLEAIADGPDFGRTYKDAPDIDGKVTFTRPVETGSIFKARVVAAQGYERELEPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBJ3</accession>
    <name>A0A1Y4DBJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56513">
        <property type="protein sequence ID" value="OUO56513"/>
        <property type="gene ID" value="B5F75_04785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="132" mass="14571" checksum="C795ED181E874219" modified="2017-08-30" version="1">MTAITCTYTGDGETELVHGPTGSTIQTDLPPDNGGKGRRFSPTDLLAAAFASCVLTIMGKMAATRKEQFEGARVEIEKRMAQNPRRVGEFVLKITFPAHFTPEQKKFYQTAVNACPVHQTLREDVKITVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL3</accession>
    <name>A0A1Y4DBL3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56456">
        <property type="protein sequence ID" value="OUO56456"/>
        <property type="gene ID" value="B5F75_04490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007437">
        <property type="entry name" value="DUF486"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38482">
        <property type="entry name" value="PTHR38482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04342">
        <property type="entry name" value="DMT_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021239">
        <property type="entry name" value="UCP021239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="110" mass="12735" checksum="76B1E0632E95B186" modified="2017-08-30" version="1">MWKTVALLCASNLFMTVAWYGHLKFKNRALWLVILASWGIAFFEYCLQVPANRIGSNYFSVTQLKVMQEVITLTVFAGFSALYFKESFKWNHLVGFACLVAAVFFVFKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP1</accession>
    <name>A0A1Y4DBP1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56574">
        <property type="protein sequence ID" value="OUO56574"/>
        <property type="gene ID" value="B5F75_05110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="271" mass="30822" checksum="15D2C7E4C1C55597" modified="2017-08-30" version="1">MTKEQDAVEHEESYIKAYEDIQLLKKDVMRPVRMELEVMKPEIYLQHFNVTDTIVCFGSARVREEKESQEKVKRAKEALAKNPTDKNLQNRLYEAEGLAKLAKYYEEARRFAKLVVQHAGDRFAVVTGGGPGLMEAANRGAFENGGRSIGMNITLPHEQRPNPYITKNLAFLFHYFAIRKLHLVMRSRAFVVFPGGFGTFDELFEILTLVKTGKKEDIPIVLVGKEFWNTVVNIPGLASYGVISPEEAESCEVVETAEEAWDVLAKFYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR3</accession>
    <name>A0A1Y4DBR3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(Fe-S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56506">
        <property type="protein sequence ID" value="OUO56506"/>
        <property type="gene ID" value="B5F75_04745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF362" evidence="1">
        <location>
            <begin position="58"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="316" mass="34334" checksum="79460879DB106DC8" modified="2017-08-30" version="1">MSCLAAGVFLAACGSNGSAPVKTEAPAQKSIVYFTSDISPEGLVKIYDKISENIHGKVAIKVHTGEPHGPNIIPREMVKALQQHIPNSNLVETNTLYEGGRHTTELHRQTIKTNGWDFCEVDIMDADGAVMLPIKGGKHFKEMSVGKNLLNYDSMVVLTHFKGHTMGGFGGSLKNIAIGCADAKVGKAMQHGSNGADLWRANKELFMEHMVEGGKAVTDHFGKNIVYINVLRNMSVDCDCAGTSAAAPKTRNVGILASTDILAVDQASVDMVYALPDEESHDLKERIESRKGLRQLSYMKEMGMGNDQYELVNLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBU6</accession>
    <name>A0A1Y4DBU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56613">
        <property type="protein sequence ID" value="OUO56613"/>
        <property type="gene ID" value="B5F75_05325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="181" mass="20271" checksum="A1F1E8A13418F10F" modified="2017-08-30" version="1">MNKIYQKPFLGVKNAGFTLIELLVVVLIIGILAAVAVPQYEIAVEKSRIAEVLTAFSNLEKAEKMFEMSNGRYTRQLDLLDIEMPGIGRDIGYGQNNWETDNYYFWAEAESYGWANRVFRIKASSKKSKKYTLVMDLNQGEKKIYCTEYAPSSGPTIPVPAGQLPDICRKLGAASDGLMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBX6</accession>
    <name>A0A1Y4DBX6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56637">
        <property type="protein sequence ID" value="OUO56637"/>
        <property type="gene ID" value="B5F75_05455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="59" mass="6996" checksum="126086A1ECCE6F21" modified="2017-08-30" version="1">MTKEEIKAKINKLKSEQTACHGTPCEVYSRVVGYLRPVQSWNKGKKEEFKMREKFSWEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC49</accession>
    <name>A0A1Y4DC49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="9">2.7.1.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">6-phosphofructokinase, pyrophosphate dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">PPi-dependent phosphofructokinase</fullName>
            <shortName evidence="9">PPi-PFK</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-dependent 6-phosphofructose-1-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pfp</name>
        <name evidence="11" type="ORF">B5F75_04370</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Non-allosteric.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56435">
        <property type="protein sequence ID" value="OUO56435"/>
        <property type="gene ID" value="B5F75_04370"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01980">
        <property type="entry name" value="Phosphofructokinase_II_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011183">
        <property type="entry name" value="PfpB_PPi_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005677">
        <property type="entry name" value="PPi_PFK_PfpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02477">
        <property type="entry name" value="PFKA_PPi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="82"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="212"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding; shared with dimeric partner" evidence="9">
        <location>
            <begin position="251"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="259"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="434"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP" evidence="9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi" evidence="9">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="564" mass="61747" checksum="DB1EA20E9CE163EF" modified="2017-08-30" version="1">MSTKHTAKCECSQLQRHRCKFQPVLPAILQKGPAFVKPKFGKATKSVADQAAVKRIFPNTYGLPEITFVKGANSAVAKKAVRVGVVLSGGQAPGGHNVIGGLLDGLKKANPKNKLFGFLGGPSGIVENKWVEITPALMKDYRNTGGFDLIQSGRTKIETDEQLKAAKDNLIANKMDALVVVGGDDSNTNACVIAEYLKQQGVDISVIGVPKTIDGDLKNKQIETSFGFDTATKIYAELVGNICRDVNSARKYWHFIRLMGRSASHITLEVAFKTHPNAVLIGEEVLAKKMTLGQIVDNLAQLIAKRAKAGKNYGVVLVPEGLIEFIPEMKELISALNDSLADNEAELSKMNTVAEKKAFILSKLPAKLADLMRSLPEGIASQLMLDRDPHGNVQVSLIETEKLLVEMIRTKLAEMKKAGKYNGKFAAITHFFGYEGRCGVPSTFDANYTYALGYNAAVLALNKCSGYLSSVRKLTKKAQDWECGGIPLTMMMNIERRKGKEKPVIKKALVELKGEPFKHLAKNRDLWAVEDLYVFPGPIQYFGPAEITDMTTYTLLLEQGKKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCF7</accession>
    <name>A0A1Y4DCF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56783">
        <property type="protein sequence ID" value="OUO56783"/>
        <property type="gene ID" value="B5F75_02765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003173">
        <property type="entry name" value="PC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02229">
        <property type="entry name" value="PC4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PC4" evidence="1">
        <location>
            <begin position="18"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="PC4" evidence="1">
        <location>
            <begin position="97"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="17145" checksum="1015D65A71B240DF" modified="2017-08-30" version="1">MSESSFTLLRDIGSCPLENGEEIRFTIDAYRGYRYVSVRRYVASDSFSGATRDGITMTPEIVRALEPLLAALPDDPKAVSNGQLGKFAKRPGICVVASVGSFKGRRGLDLRQWQEDCGFTKKGIWIPLEKLPQIKQLFLKTKEALDERPDDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCH8</accession>
    <name>A0A1Y4DCH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56585">
        <property type="protein sequence ID" value="OUO56585"/>
        <property type="gene ID" value="B5F75_05170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="144" mass="16037" checksum="0236E0DA394A5A9F" modified="2017-08-30" version="1">MNVFSACTLLFAAAFLAATLLPAQSEGILFWLVYTQKYPTALLLAFATAGNVLGACVNAWLGRYLARFQHKKWFPFSPRQFEQAKRFFQKYGVWALLLSWVPVIGDPITLAAGALGVRWPVFLLLVTLAKLGRYLVVCHAAGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI5</accession>
    <name>A0A1Y4DCI5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_02945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56817">
        <property type="protein sequence ID" value="OUO56817"/>
        <property type="gene ID" value="B5F75_02945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="25156" checksum="742AAC0C4E1AC344" modified="2017-08-30" version="1">MNRYLALSGGLHILAALFLLLLLAPSAKKAAATYTIDFIGTGKVVATTGQEAASPVKAPKAAVQAPAPAKEAVAKPAPKTNKKAYASKSEITTKKQTKKAQPKPAPLAAPSVLDDAADSKAQAGGGTASKEGEFAGGNIQTDFANFPYPWYITQVRNSLWIEWEKRRPAGTELSALVSFAIARDGKIKDLQVARKSGDDTFDFAATSAVINAGPFAPLPMYYEKDELTVSVEFRQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM1</accession>
    <name>A0A1Y4DCM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="4" type="ORF">B5F75_06930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56342">
        <property type="protein sequence ID" value="OUO56342"/>
        <property type="gene ID" value="B5F75_06930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="89" mass="10224" checksum="48EB878887AEFB60" modified="2017-08-30" version="1">MENQESRAKRKVLTGVVVSDKMNKTRTVTVERLVHDERYGKTLKRAAKFHAHDEANESKIGDKVEIMSCRPVSKTTKWRVSKIVEKARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCT3</accession>
    <name>A0A1Y4DCT3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56665">
        <property type="protein sequence ID" value="OUO56665"/>
        <property type="gene ID" value="B5F75_05595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025518">
        <property type="entry name" value="DUF4406"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14359">
        <property type="entry name" value="DUF4406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="110" mass="12341" checksum="36223E92EF5EA531" modified="2017-08-30" version="1">MFKVNTKNIALTQTVYLSGPMTGLPDYNRAAFNLRAEAFRAAGYSVKNPADISVTHGTDKAYEFYFKRALRMMLDADVVYVFGDTTQSRGVEMELQVAKMAGMQVVWEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCT4</accession>
    <name>A0A1Y4DCT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FTCD_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56422">
        <property type="protein sequence ID" value="OUO56422"/>
        <property type="gene ID" value="B5F75_04300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="FTCD_C" evidence="2">
        <location>
            <begin position="8"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="20356" checksum="C8157994DFA0E026" modified="2017-08-30" version="1">MEWYTAAERFTEALASSEPTPGGGAAAAMAGAMGCALAIMAVGTTLKRKATPEDARPRLTQSLKRLSAFKNELKGYIQKDGEAYAAYLTAKKLPKESAEREKAVQDALLFAARVPADAASAAMHCLREVDAIKSDVAEIILSDIYCAKHLLQACIKSSVESIRANLSFITNEDRVNEINKQIASFLKVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCZ1</accession>
    <name>A0A1Y4DCZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OmpA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56482">
        <property type="protein sequence ID" value="OUO56482"/>
        <property type="gene ID" value="B5F75_04620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="80"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="23270" checksum="B2BA2264565DB63C" modified="2017-08-30" version="1">MDNWEYGNCYTFFMWFCYNLDRRKLMKGKSVLLFLCAAALCACSSAQKQDEDIPRPAKRDPIIEEQAKKNEKLYNQSEARMAKTLKLPAITYEFDSIRPPDYAYPFLDKVANVMNSHPSLHLIVEGHTDVLGSKEYNYWLGASRAAAMKAYLVSRGVNAERIRIHSYGKDRPLTLDNSSDGRRTNRRVEFSFTTRVWNAIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD20</accession>
    <name>A0A1Y4DD20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57023">
        <property type="protein sequence ID" value="OUO57023"/>
        <property type="gene ID" value="B5F75_04035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="272" mass="30549" checksum="DDFDBB115092D910" modified="2017-08-30" version="1">MTLLVILALLAVVAVYAVFFLVFKLIWILLKKNSNKWPLIWAGVCTVVFGVLFVGFTAWGVYKVVSPFKGMITRLQNNPQPVYGERVYTDPVYRFDLDVFNGMDFSNWMEFDDLDAKVGVDMNAFRNYPSDEEEDANERQFMAVLLLRQDDVDEGHPLQALREALASTDHRQDLEILSQEDFTLDGYPAMFATGRAYARNGKRMFLAVTAVADAYRQVFYVIAFSPDYPEAVENATQTARSLRLENGSSLPGETAPALPQEEAAAPAAETTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD21</accession>
    <name>A0A1Y4DD21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_03780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56977">
        <property type="protein sequence ID" value="OUO56977"/>
        <property type="gene ID" value="B5F75_03780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="73"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="277"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="44129" checksum="4B29BE0CA8A65A96" modified="2017-08-30" version="1">MQKYTYTVKDANGKTLKGSVSADNREKVILALQNKGYLVLEVKEGTSGLFGGGGGSKTRKKGGKVPGHVLAFFAEQLSTLIAGGVPLVRAVSLLGEYASNPTLGYVLTQVAKDIAGGQSLHTALSHHPKTFSHIWLSLVQAGEVGGQLADTLMQVALYTKTQESMKSKIITAITYPAILTIASVGVLVYFILGIVPTFAQIFKDFNIDLPMITVIVLNVSGLLINNGILLIVLTVFLIVAFRFYIKTTDGKKRWHSFLLSMPIFGNFLKNIYYDRMLSTLSTLLKSGVTILNAILVLEESFDGNVIIQNALKHVRAEVAAGKSISESFRDTGVFPGLMTEMMLMGEESGKLPSIIATLSKFYSDNVDQFIARFSAVIDPILICGVGVLIGIIVASIFLPIFKLSQIGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD25</accession>
    <name>A0A1Y4DD25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF5107 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56522">
        <property type="protein sequence ID" value="OUO56522"/>
        <property type="gene ID" value="B5F75_04835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="312" mass="35000" checksum="F0CB5518FF81DCEC" modified="2017-08-30" version="1">MTQTTYKGLPAWTLENNALRVTFLPGYACKMASLISRKTGREFLFQSAQDTLRVPAYGASFADYDSSGFDEVFPSIDACPYPDGSFRGTPIPDHGDIWALPWESVCSPDGKAAKAFVKGPKLPYIFSKTITLKDNAVQLEYCVENTAEEDFKFIWTPHCLLACSPATRLLVPENLKQVMSVEHSTKRLGPWGTLHSYPLTVDVRGLKLDLAATEPRTVRNCEKFYFTEKNTAGWCGIEHTDTGEKLIYNYDADKVPYLGVWKTQGGYRGDYNLALEPCTGVYDDLYVASKIRRAAVIGPKGRYEWTFKMTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD72</accession>
    <name>A0A1Y4DD72_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56815">
        <property type="protein sequence ID" value="OUO56815"/>
        <property type="gene ID" value="B5F75_02935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="318" mass="35514" checksum="73CB3FBB42E91845" modified="2017-08-30" version="1">MKNTLLITGGNGFIGRALTDKLLQEGFNVRIVTRRTPKEQPANPSVTLIQADYNDVESLKRALKGCVGVFHLAAAIFGFKREDFEKANVTATRNVVQAVNEMPEIKTFVHVSSLAASGYAPDKDHPRTEEMTPNPVSDYGITKWGGEQAVHTLRPGVKWTIIRPPIVYGKNDSGVSKIALWVRRGVMVNTSGNGYFSFVHVDDLVQALWLAFARPDTDKQTFFVTEDAVYSWDYFITEMARAMNCHKPFMPHAPKWLLRTAAWIYELAAHISGAQPALNYDKVTEATVPGHWICSGKKWQQLTGQKFTPLAEGLKKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDA9</accession>
    <name>A0A1Y4DDA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56855">
        <property type="protein sequence ID" value="OUO56855"/>
        <property type="gene ID" value="B5F75_03140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="449" mass="50542" checksum="C7BEE8952D9EC753" modified="2017-08-30" version="1">MIKKLVIFLWILAAVLVAPPLLRSFGLSPKEMVKDLFAPAPRPDVIEPVKPASVKPVPLEPAAAPQEDERGRARELRPEISLPPMPEPRTPNAPSNQADQKQFDEMISGLEKIVTIAPEDSIEDLPAQVFRPADSAQKVRWMPPPPGFLTADTFNYLIYREKNPVTPTIKTVLDNIHGNLMLDLTPFTIIIKPNKILVMLFGQKNSYMAFTKRPAWSGASSDLRADTMYVIEGDSFYPLSVHELTHLYFDGYFLPTISPLWLSEGMAVYMQINTTKQKPSWVDRSLRRILKGEIIPFEEMTVLETLDAYSTSQAELWYTQAYSVVSYLLKTRSRDEFYRFCNELKAKTPLHQALYRAYGMPFNRISVLENVWRHDLQKAYEEGKILQSDAKKASAPAQRPAAAQAAGKPVSNPAPARPAVQKSSQPAPQKTKINKLQMVPTNSYKGGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDD1</accession>
    <name>A0A1Y4DDD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56642">
        <property type="protein sequence ID" value="OUO56642"/>
        <property type="gene ID" value="B5F75_05480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="73" mass="8480" checksum="4D81507C87C3D4B1" modified="2017-08-30" version="1">MTPDFFNAAWKIAALVFAAGGMWSELRAIRKDIARLEAKQDKYNTLQERVARLEDSCANAHKRISELHYNRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDN1</accession>
    <name>A0A1Y4DDN1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56975">
        <property type="protein sequence ID" value="OUO56975"/>
        <property type="gene ID" value="B5F75_03770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="16551" checksum="3DF7D954F906A8B3" modified="2017-08-30" version="1">MKKNNKGFTLLELLIAATIIGILAVFATVAYRESAAETRLAGAKAQAEALANAVQRYRMDPAACTLITSNSTLNISNLVNCGYLEKSFSYLLEDPYFSFEICTGGNSIICPSSTYLACMSGKSEKLPNRYLAKQGYLYCFENSGSVLEIVGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDP3</accession>
    <name>A0A1Y4DDP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57217">
        <property type="protein sequence ID" value="OUO57217"/>
        <property type="gene ID" value="B5F75_00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="1">
        <location>
            <begin position="39"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="243" mass="27349" checksum="62734B6EFD77A960" modified="2017-08-30" version="1">MKKIIVFVVILLVAAVAAGLLFFRHTPFAYSGVVEAIEVDVPSRLSDTISQINVQEGSAVQKDEVLARLDCRDTRLKAAIAQKEFTRAETLLKTTAGSRENYDLKKHQYDQAALYESWCEIKSPIAGKVLYKYYEPGEFIAAGRKLVTVADLSEVDVWVYVEHDLLARLAVGQAVEGFLPESDQHFEGRILSINDEAEFTPKNVQTRRERERLVYGVKTRFKNDAARTLKSGMTLEVSFGEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDQ7</accession>
    <name>A0A1Y4DDQ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">B5F75_00285</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57253">
        <property type="protein sequence ID" value="OUO57253"/>
        <property type="gene ID" value="B5F75_00285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="129"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="238" mass="26793" checksum="60249CB5A48A7F5A" modified="2017-08-30" version="1">MKIDVITAFEEMIDHTLSHSIVGRARKAGIIKLGTLSPREFAEDKHKTIDDRPYGGGPGMLMKAEPLYQAISKLRKKGSYVILTSPRGQVFNQELAKKLAKKRHLIFVCGHYEGIDARIYPEVDLEVSLGDFILTGGELAACVMIDAITRLRPGTFKKEGVTSSESFEGHLLEAPQYTRPEVWRGRKVPAVLLNGNHKEIEAWKHEQALALTKQLRPDLLENASQKSKKVQKKKIRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE27</accession>
    <name>A0A1Y4DE27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_00515</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57296">
        <property type="protein sequence ID" value="OUO57296"/>
        <property type="gene ID" value="B5F75_00515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="134"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="414" mass="45762" checksum="5902E9205B882F05" modified="2017-08-30" version="1">MLLKQMNKVFIQTYGCQMNVADSDEMFAHLAARGAVLTDKLDEADTVLINTCTVRDHAEHRAVSFLGRLAAWKKEKPGRVIIFAGCAAQRLGSALQKKYPFLDILSGAKNIEHFSDTLDKSGLFGTPSAAGALPAPGLTGYVTIMRGCNFACTYCIVPSVRGPIKCLPVQDILQEVARKTAAGAKEIMLLGQTVNAYEDGAVSFADLLNRVSEVPGVERVRFTSPHPIYFTPAFLNAVKANPKIARHVHLPVQSGSTKVLQEMKRGYTRELFLEKIRALKACGFNISTDIIVGFPTETEDDFHQTLTLVDEVQFFIAYCYKYSPRQGTPAAQMKLLPENVLEERLDILLNKVRGLSDAAYQKQVGSVQEVLMETEDKGRSSENFWVKTKQKHPVGSLVRTTIERADGTLLFARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE46</accession>
    <name>A0A1Y4DE46_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="7" type="ORF">B5F75_00930</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57367">
        <property type="protein sequence ID" value="OUO57367"/>
        <property type="gene ID" value="B5F75_00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018278">
        <property type="entry name" value="Ribosomal_S21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21109">
        <property type="entry name" value="PTHR21109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01181">
        <property type="entry name" value="RIBOSOMAL_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="64" mass="7943" checksum="2A1454EE6A53125F" modified="2017-08-30" version="1">MVFVKVRDAEHLEEALKRFKRECEKNGILKEIKRRETYMPPSVKRKIKSQEAQRRARRTKRRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE47</accession>
    <name>A0A1Y4DE47_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57316">
        <property type="protein sequence ID" value="OUO57316"/>
        <property type="gene ID" value="B5F75_00635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="216" mass="22897" checksum="46D0B7D0A7E21A1F" modified="2017-08-30" version="1">MRKTLIFKTEEMTPEYMLLAAQALEKGAVAVLPTDTVYGIGTGAFCETAIAEIYRIKERPATSPLQILTGSLRQAHQVARFSPAAEKLAQAYWPGALTAIVPPSDKGKPLARGFAGLGIRVPGNTFLVKLLSLMQAPMACTSANLHGQPVLTDEKGILETFKGKVDYIFLGGTLSPTASSVVDLTGETPVLLREGGIARAALEQTMGLALQGKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE68</accession>
    <name>A0A1Y4DE68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thymidine phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57423">
        <property type="protein sequence ID" value="OUO57423"/>
        <property type="gene ID" value="B5F75_01225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017872">
        <property type="entry name" value="Pyrmidine_PPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00647">
        <property type="entry name" value="THYMID_PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="365"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="454" mass="49255" checksum="47D80B940FDE4E1C" modified="2017-08-30" version="1">MLCWNSLPPRRKKEAATMRMIDIIIKKRNGKTLTQEEFNFVANGAAKGTVPDYQLSAFLMACFLRPLSDKETALFTKAMAHSGGRLDFSSVKLPKVDKHSTGGVGDGISMALAPLVACGGVAVPMMSGRGLGHTGGTLDKLESMKNFEVRVPVKLIYRQIQKLGVCMFGQTQDLAPADKKLYSLRDATGTVESRPLIVASILSKKYAEGVDSLLMDVKYGSGAFMQKLEDSRKLARALVSTAKLLGLKCRALITYMDQPLGRAIGNANEMLQTVLILKGNKELAPDFYELLIEEAANMLVISGKVKDVKKARALMEEKIANGEAAAKLREMIKWQGASPEAVDNPVKYFKNAKLKFEFKAAANGFVEHIDAKTAGMAGVLLGAGRNTMEDAIDYGAGIWLDKKAGDAVKKGDVIATLYASDKKRLEDGAALFTQAVKIGKKKPAPYKIVKEVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA3</accession>
    <name>A0A1Y4DEA3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="5" type="ORF">B5F75_00975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57376">
        <property type="protein sequence ID" value="OUO57376"/>
        <property type="gene ID" value="B5F75_00975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="8"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="205" mass="23487" checksum="7F7D257EF33FB499" modified="2017-08-30" version="1">MRGKFIVLEGPDRCGKSTQAKMLYNQLVARGKDVILTREPGGTPTAERIRQIVLEPGLDVRPLAELLLYEASRAQHTQEKILPALAEGKTVICERYTMSTCAYQGYGRGIALETIDILNKIATQDTQPDLTLVFLMSDKYFTERGEYLFSDRLEQEDLAFRQKMRKGYLEMIDRTPHAYLIDADKNIRDIQARVLKLLEEHHIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA5</accession>
    <name>A0A1Y4DEA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57473">
        <property type="protein sequence ID" value="OUO57473"/>
        <property type="gene ID" value="B5F75_01495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="8">
        <location>
            <begin position="366"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="7">
        <location>
            <begin position="507"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="765" mass="86405" checksum="8CE6790436620B65" modified="2017-08-30" version="1">MLLSKKGYPCPKYAQGRGIHVKKFSSFWQFSVLILLCTAVLSTGIFLYVNRLSTLLHNNTKTYLAEVAKQGVNTIESKIQDDFNLLQSIATAIGVIPNPTEQMITRLMKAESKTNNFKRMGFVYPDGIAVLSDDLLLDIHHEPHFTKAMAGTPNVSNLIKDASDGKNIFVESVPVYHQEKIIGVLFATRSTEEYTQALDIESFGGEGYSIIVRANGDKIVGASHKNAVSGMYNIFNSPDDPDHELAHNIQQALKNRRSGTIHYLSAEKGELHISYEPLKINDWYLFSVVPTAHLSAQLNAFITLLLILCLAIAVAGLVVWGYVFLQQKKNKEQLFNYAYVDPVTGFPNAEANRTAAEQLLKENPKGHYAMVALDVSKFKIFNEQHGYEVGNILLKHIARLIKNNLQPQELCTRIYGDYFAMLLKYTDEGTLKNRLELLGEQITNFQTENHHAYAVLLSFGVYPIEDKSMPIRVMYNRAAVAKSQIKGRYDQIVAFYKPDWQQKLEEEDFIERHMQHALKKGEMKVLLEPIVSLENGKIGAASVTAEWKIEKEKKTLYSRQFLPVFQKNGFIYQFDLFLFEQACKILAQWQKEKLPLIPLVINLANELFLDVHFVQHLTQKTTEYGILPKWIVIELTETAQTEFLPQLERAGAALRKAGFGLTVRYSGQGVTLSNIFQHLPVEGIKIAPGVWAPNASEKQQLLARAIVEMCRKLQVFLAAEGVQTPQETEHIKKLGFQFAQGSGLFPTVTAEKLAEQFPRTQENSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA7</accession>
    <name>A0A1Y4DEA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57474">
        <property type="protein sequence ID" value="OUO57474"/>
        <property type="gene ID" value="B5F75_01505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="2">
        <location>
            <begin position="35"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="3">
        <location>
            <begin position="193"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="398"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="562" mass="64802" checksum="92AAA55135DDE5D9" modified="2017-08-30" version="1">MATPDPKNYRYIRLNNFYKIRKCSMLNKENQFQEKAVIFLRVSSIKQEDGYSLDAQEKLARSYAQRNNLQIVKMWKVQESAWGKKERKEFSAMLDFVKRNDSVKHVIFDVVDRMTRNDADKIRVIRLIREYHKSIHFSRTNQLLNDQTLDSNKEFMMDVEVAASKKLSNDIAYKTRMGMVEKAEQGIYPGNAPLGYINVTTKEKESIIEADPVNAPLVTELFEYASTGKYSLEELEEIFYGKGLRTKSRGNRVSLKSISKMLHSPFYYGVFKWGKKIYQGTHTPLVSKAVWDKTQDSLAAKAHRYDTRHNYPFNRLITCEHCGHYILGAKAKHKYLYYRCAHYNKDHKKSGYLTEARLAEQLADTIQDIELPKEVVEVLCKGLKQKGLRANQINAGTKQILQKELERVNGRIEALLDMYLDRKITDAAYQAKNRQLQEERERIEGELSRCTRSAEGAQRAVQGLAMLSGLKKCYREADNYGKADLLRAVGAKFLLTQDNQIVVEYKEPFKAIYEAKHLAQTDAKEAERDKKTALLNKGCLEIYDDKSAQGASQSCSRNYWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC6</accession>
    <name>A0A1Y4DEC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57255">
        <property type="protein sequence ID" value="OUO57255"/>
        <property type="gene ID" value="B5F75_00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="420" mass="48927" checksum="7E208A1D4D701CA8" modified="2017-08-30" version="1">MKTLSLVRLTSFFLALLLTAQPAVYAQKLSRKALRALRAQEAAEIKKIANSSSNAALRALQNDLFAETYAAASRFSKNVSNPRSKKSRQRFFDEYTAKITEEQISQFVRLEPPANYKKRKSSKNLPFDPYPQIAEMVQEEKNPLRALNTVHKMEDKFPGHSFFSLFAFAYYRQYFSVVTPHLKELFKRVERLHDRGLETRFAKRMRFLAENRDAFRRVFAPNIPKQGMRIRYTKDISKLTPDSFNAANLVFSFERKMNPGQDNAAIRHISAKTIFPVGKNKVFPVYYYNGPFEYLPLLYRYLLNGNHPKKEITVILDREAKSMAIYNEDKTLWLRITPHEYSFPDRLHLHLNEIRTAEIETILGITQEETVNFNLSIPLSTPSNLPTTNRDEFLYNEMILKPVNHLKSSQHVTVIERTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DED6</accession>
    <name>A0A1Y4DED6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">A2M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57265">
        <property type="protein sequence ID" value="OUO57265"/>
        <property type="gene ID" value="B5F75_00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012983307" description="A2M domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1980"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="3">
        <location>
            <begin position="1231"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1980" mass="221268" checksum="A4CC2BA0E3463A7A" modified="2017-08-30" version="1">MKKTIRLIGALLFFPLALSAQSLPKAEEAYAQGDFSRALTQYEAVLKTATGDDRLQAQLRKASCEYGLGEYMTAAQTMLSYDLPADDLWKARFLLYRIQMAEQVAAVYPSLMNEREIAAPNTSPEQWTLAQWNQQIDRDYQTLWALRAALINDPVERETLILDIQKTDTRRIPTLFDVVVHNWISRLQGQNAPVPLAREEAYFLDGTAQPLASRQETAQQLAYLLETAYLLDGKNRKDAKTFWRTQYILLPFDSPSLFRLTQPEKALQKAVEQLQLISGYTPQKMGFWNKLKNYVSPEGTAYGRSYAAYRAAQLLNVHDDPETALKICQYAQEELEGSYYTSLCEQLAQQITQNELSFDRLPQAYSHRPEISFSVRNAPAVYVRVYPTSREELQRLYHQVYLSDTVNSWNFLSQISSKNIPLFLDRAPLHTLSQAVSYEKPYRSKKISLKLPELENGFYVALASWDESFDEDKSPVLATVLNVTDLALFVTAAIEDNPDKYTAELTGSAHTYRPDLFRFYTVNLKTGLPEGNADLDIITAWNGTRQRGFTTEDGSSSVAREIVVSPNNDKRSSHFVNVLAQKDGSQAYTANAVYFHFYNKDLIRLFAQTDRPIYRPGQNVQLAVNAFEVLPRGLRVLPGRRVEIEVTNASGEKVFSAAPLLNEMGTASAQFVLPEETMLGYFQIRASVTAGGRSFRTYNSFRVEDFKRPDYELTLGDPAKTMEYGKAASIGGHAQYYMGAPLQNATVQYTVSRQRYVPPFYWWYPRILQAENTLLAEGKTTTDENGDFTVSFTPAAPEEEDASFAKYVVTAEVYDESGRAIDASRTYTLSAKPKLFKVEFSQGFYDAKKEISSLATIDLTDAQGKSVSGKVTVQVARLQNKLPQLEDEVYAHRTPSLEEWYQNAPEEKTVFSKTLNFKTPGPQKLALAALEEGVYRLKLKSDKADPQQMIFIVAAEQSALALPDVTLVQHAAYYPGETARVLLGAGALEGSKRVEVYWGDTFLKHKDLLPGGVSVYSFPVEQEERGGLAVAWFGASNYTFHQGSAQLEIPFDNKELGVTLDVPASVRPGETTAWKLTAKDITGSPVSGQASLTVYDKSLDYYAKQENPFTLASLFSQNTSLGDRSASALRGSFSRAYNAPERPYLVPPTLPQLNLRLPVRFFRNMAVAGGAMLTAAPQLMKTASNVLLQQESAVMDTAAAAPAESRSAYAEEEAASDDAAQTALRTDFSETAYFNPALPLVNGQASVRFTMPQSLTAWNILGFVLTKNADFGAFSAQTVTRKDFMVRLQMPRFYREGDKGVLQAALTNLTDKKLTAEVDIALRADNAPANEAFGLSKTKKSLAVGANSTEFVTWEITAPSQPALYQATVTARSGKNSDGEQKTLPVYPGKERLLATVNTALKNGENTLEITELNDVPDAEAQTAVLTLNPSLALSVLNSMPNLLSTRYNDLVSSLNRYVPLAVVNTFYTQYPQLKEAVAKLPKRTGVNASWNESDPLRLTLLQQTPWLRQAQGAAVHTADIIDLFNPQIVAKTKAKEWARIVKFQNANGSFAWFPGGQEDEYLTLYALHMFAQALSYGADIPQEQAQKAFAYIVPRIEKRLQDDKTGSETTVAFALYAAYTLSSFPPNWAQTAQAKPYVKRWADYADQLARFMTPLGQIYAASVYHRLGDDVKANRYLDLVLSRMKQDELTGAYFAPEPQSWVWYRDTLSTQTTTLRTLLELRPESDKIDPMTQWILFNRQVNEWSDPKAAAQAMFTLLKVMQHKGALSLPVEYTVQWGGEKKSFSFEPFDWTEDLQLVRQGGQITPQALRAQITKKGVLTDFASLSVIYQSAQAKASPKGVLNVTRKYYTRFTQDGVQKIRPVQDLGEVQVGDEVEVHLTLTSDSAFEYVLLTDPKPAGFESDELTSGWTHEPLWLYRENRDAETNFFINWLPAGTVTLRYVLRPTLEGRFHALPAQTQSMYAPEFGAHTAAEVLSVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG4</accession>
    <name>A0A1Y4DEG4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="7" type="ORF">B5F75_01350</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57446">
        <property type="protein sequence ID" value="OUO57446"/>
        <property type="gene ID" value="B5F75_01350"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="488"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="223"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="563" mass="61206" checksum="8AC09ADE16463DB4" modified="2017-08-30" version="1">MEKEQDVTVAKSAGFCPGVKRAIDKVLELEAAGKKPVYTIGPLIHNKQVTDMLAAKQITSIDRPQQAADKSGVLVIRAHGITPQFQQEIESCSMEVVDATCPLVKHAQNIIAKFAQQGYHTVIVGDGGHAEVIGLLGYTQGKGVVVSGPEEAARLPHFDKVNVVSQTTQQEIVFYQTAEEVKKHADVCQISNTICQPTKDRQKETIELAKSADLVIVVGGRHSANTARLATLCKQLAPAVLHVETEDELEPLPVQRARKIFITAGASTPNWVIDRVAARVRELRKPNAKSILSGWLEKTWRFLVRNCFYTAFAAAALTYVCMRLEGVPTDGRLLTFAGLFVFALTAFNRGAETDPGLNKRFLTAASLAAAAGAILCAGFIGKGALGMGLVFLLAGFAYPYRHLLKLQLVSLPGTKDIVTALGWAYACAFLPAYTHGMALRKAAYLAVFYTVLLVFMRSVTLGFTSANKDLIIGRESFYKAFGMKKTKWAVTLVLAALTAALATLLSLTWKPALVGMLLIGHLYTVFIVIYYYSKSSTRSVKDETLIDGQFFVLWAVSALAAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI5</accession>
    <name>A0A1Y4DEI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ORF">B5F75_02020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57573">
        <property type="protein sequence ID" value="OUO57573"/>
        <property type="gene ID" value="B5F75_02020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="609" mass="67767" checksum="42CCED1C1C62CCB7" modified="2017-08-30" version="1">MKIRNFSIVAHIDHGKTTLSDRILEDTGTVPKRKMQAQLLDGMDLERERGITIKAKAVRIQYKDYILNLIDTPGHVDFSYEVARSLRACEGVLLLVDASQGVEAQTVAHAHLAQSLGLKIIPVMNKVDLSQADADASEEQLWDILKEPIEAERVSAKTGMGIEHLLDRIITDIPAPQGDPNAPLRALIFDSYYDPFRGVIMYIRLVDGSVKPGQMIQFMSSGASYKTEEIGFMTPKQLHKTDSLSAGEVGYLVAGIKDIHQVKVGDTITLAERPAEKALPGYAEAKPVVFASIFPVETTDFPLLRKALEKLNLSDSSFHYQSETSKALGFGFRLGFMGILHIEIVKERLEREFNLSLIATSPNVVYHVKFTPRKSHPQELAALPDAPDDPGYKIIDNPANFPPHGDIIDIKEPVIHITIVTPVEFMDGVMTLLKEKRGTFMSMDHLSNQRVIIKYEMPMGEMVIDFYNKLKSVSKGYASFDYEVAGFRSSDVVLMEILLHGTPVDALSVVVHKDKAQTMGRALCAKLKELIGRQQFEVAVQAAVNGKVIARETIPAFRKDVIAKCYGGDITRKRKLLEKQKEGKKRMKAIGSLNIPQEAFVAMLKIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK6</accession>
    <name>A0A1Y4DEK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_01725</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57517">
        <property type="protein sequence ID" value="OUO57517"/>
        <property type="gene ID" value="B5F75_01725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="20"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="324" mass="34242" checksum="3764961C50F6087A" modified="2017-08-30" version="1">MNYIHPLQIGSFTAANNLLLAPMAGITDSPFRVLCLKGGAGIVCAEMVSAHALHYGNAKSGRMLQVNPKEHPVSMQIFGSDEATIAEAARNAEAQGADIVDLNAGCPVKKINKAGAGCVLMKDEAKLGRLIEAAVKSVKIPVTLKTRIALTHKALLGARLAKLAQNAGASAVTLHARAAVDVHSGPPNIEAVAEACSAVTIPVIGNGGILTADTARQFLQAGCAGVMIGRGAVGNPFIFQDIQDAFAGKEPSSHTPKSRLAVYLDLIRENVAYYGERIGVNRSRKTAGYWIKDFPNAAEVRGLFVRLDALADIEKLFTRTLQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM5</accession>
    <name>A0A1Y4DEM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57526">
        <property type="protein sequence ID" value="OUO57526"/>
        <property type="gene ID" value="B5F75_01770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12739" checksum="4734D26DA4393DA7" modified="2017-08-30" version="1">MSKCCKCSKWWPHNWLCLKGLSVIFLVLFYLALAYAVFQAYAIFTYPMLHGSEMWISAAFYVASDVAAAIGFLTVAKILKALRKIKKAVAPCVCSVEEKPAPSEIEKVVEKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN3</accession>
    <name>A0A1Y4DEN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57365">
        <property type="protein sequence ID" value="OUO57365"/>
        <property type="gene ID" value="B5F75_00915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="22"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="262" mass="27913" checksum="C77F8BB7C16EA8B9" modified="2017-08-30" version="1">MNIIVCIKQVPDSTQVKVDPKTGTLIRAGVPSILNPYDHYALEKALDIKAKTGAKVTVLSMGPAQANAVLRLALALGADEGVLLADRALAGSDTWATSYALAMAIRKIGQYDLILCGQMAIDGDTAQTGPGIAHHLGIPQITFCESIDANGNQVVVKKLIDGGHQILEADLPVLVTMTMPHDYAPKYPSFMAAHKAQDKVTLTWSAADIAADPHKIGLEGSPTRVDRIFPPPARPKGEMFTGSAVELADKFVEILKKESVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES0</accession>
    <name>A0A1Y4DES0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56219">
        <property type="protein sequence ID" value="OUO56219"/>
        <property type="gene ID" value="B5F75_06265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="642" mass="72075" checksum="A453B3889D93CE2F" modified="2017-08-30" version="1">MKKTIWKILLFIVCLAAIVFLLLPFLETTPAPQNTAAAPKATPQIFTSNPLTELVNRIARFFGKRQQQAPQNAPALTAQQANEQFGTPQGEEVYADARAAQNYISTEQTPSSTPQRKNSFENAAFQDEEGEWVLIRQKTPELGTPGMHEINTKDNAYDSYVRQERAARFTPVAQVKKKKEVPDSKFARFFNPIKRFFGFGNAKENLPDTARWQEQDAAMLASSQGIGRSRNTTGSRFARGGNVNMAGINGDLPTETSASDSQTPLLSYLDPEQTVDDVSSFLADSRYPNPRTNEEQQEKEKYREQRREQAMNYFNERVEERLNRLAAGQEPQDELKKMLQLACSNSAMRPVKMSVCGYPAPAPATQDEIQAAKEENQALFSEKIKTQMPPTAVMPIIGKATEIPPALVSDKSSESYLRTMEIYNFMFNNSDCASRPCYWVANGIQTNTELQDATAGAANATLKGDPLGKYSTIQQQFIEYKQSQSQGQPQDPQTLQKQTEDFAPAYILYTVDELKQLQARNKQAMINQDHSAGIALYALSAPIAKQLTQDLQSPTFFYGRNDAFIDADNYPTFQERATVLTNDLADQIQFFKQVAQELRRNAAREVVEESTKARAKEIFKRAQEERKAFDQSNNLGNAERGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV5</accession>
    <name>A0A1Y4DEV5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57627">
        <property type="protein sequence ID" value="OUO57627"/>
        <property type="gene ID" value="B5F75_02300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="290" mass="33113" checksum="64776159EDD44F52" modified="2017-08-30" version="1">MPPLRGRRYPICTKTVKSMSTNVQSYKKSSFGPAFFFLSKRRREALAHYYEFCRLMDDLADEPNIPNPGRQLDDWEAEVHRMYDGTPQTELGRLLQADAREFSMPPDRFLLLIEGMRADLTGRTYPTQQALDWYIYRVAAVVGLATLDILGVQGKQAEALAWQEGAAVQLTNIIRDVPEDAKLGRVYIPEELLTRFGLTRQDVLDNRAPRVLAAALQELAAQAEAYYEAAFKQMAGFARLKMIPCRVMGYVYLKNLAKIKKTGFLFARPVKLTKNEKLYSIAYALFKTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF09</accession>
    <name>A0A1Y4DF09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoglutarate oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56299">
        <property type="protein sequence ID" value="OUO56299"/>
        <property type="gene ID" value="B5F75_06700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="51"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="247" mass="26532" checksum="E3E1F8FA82FC5675" modified="2017-08-30" version="1">MTIIAKKPASLTDLPMHYCPGCGHGIVHRLMGETFDELKIADRVIGVAPVGCAVFADSYFACDMVQGAHGRGPAIATGIKRSKPEAIVFSYQGDGDLASIGMAEIVHAAVRSENITVIFINNAIYGMTGGQMAPTTLVGQVATTAPKGRDPKLQGWPINMCEMLAQITGAKYLERVAVDSPQHVMQAKKAIKKAFENQVNGVGFSMVEVISQCPTNWYASVPQSLEFVRTKMIPQYPLGVFKDEGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF20</accession>
    <name>A0A1Y4DF20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="9" type="ORF">B5F75_01715</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57515">
        <property type="protein sequence ID" value="OUO57515"/>
        <property type="gene ID" value="B5F75_01715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="131" mass="14319" checksum="BF3CB804C1C16C21" modified="2017-08-30" version="1">MNNTKELKTGRRKTSVAQVELLKGKGVITVNAKSLDEYFGNHARCKAAVKAPLVVTNLEKEYDVNAKVIGGGVSSQAGALRHAIARSLAAISEDLKKAVKKAGYLTRDPRMVERKKPGQPGARKRFQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFG2</accession>
    <name>A0A1Y4DFG2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="15" type="ORF">B5F75_01005</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57382">
        <property type="protein sequence ID" value="OUO57382"/>
        <property type="gene ID" value="B5F75_01005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="13">
        <location>
            <begin position="40"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="14">
        <location>
            <begin position="220"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="611"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="688"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="611"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="837" mass="94828" checksum="52A78C964AC0A79B" modified="2017-08-30" version="1">MSIDNFPQIDKKQQDRWEKANLFASPRMPKGKKFYCLDMFPYPSGAGLHVGHPEGYTASDILVRYKLMNGYDVLHPMGWDAFGLPAENYAIATGVHPRITTHKNIANFKRQIKSIGLAYDWSREIDTTDPKYYKWTQWIFLQLFKKGLAYESTVPINWCPSCKTGLANEEVFNGKCERCGHEIERKALRQWILRITNYAEKLLEGLDKLDWPESTLTMQRNWIGKSNGAEVKFKLDGHDDILTVFTTRPDTLFGATYMVVSPEHPILKKIVTPEQKAAVEHYQAEAAKKSDLERGDLNKDKTGVFTGAYAINPVNGKKIPVWTSDYVLMGYGTGAIMAVPAHDERDYAFAKKFGLDIIEVIKSEQGVEKEAFTGDGELVNSGFLNGMHVQESKAAMIDWLTQRGLGNAKTSYKLRDWVFARQRYWGEPIPIVHCPKCGVVPLPEDQLPLTLPEVEKFEPSGTGESPLSTVESWVNTTCPHCGGPAKRETNTMPQWAGSCWYYLRYMDPHNDKALVDPEIEKAYGPVDCYIGGAEHAVLHLLYARFWHHVLFDLGVVSHPEPFQKLRHQGMILAFSYRDKMGAYHGYDEIDFKDGKAFLKTTGEELSPMVEKMSKSKKNVINPDEILSQYGADAFRMYEMFMGPFEASKPWDMKGIEGISRFLKRTAAWSESVKLFEGPDPKKSEILKNKTIAKVSEDIENFRFNTAISALMVLFNDISKLPQVSQDTFQTFLKLLHPFAPHLTEEIWQQKGYEGFVVKSAWPKVNPDLLQDDSVEIGVQVNGKVRDRISVPANASREEMEKLARASAKVQRSLEGLEIKKVIVVPGRMVSFVAAPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFJ0</accession>
    <name>A0A1Y4DFJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57705">
        <property type="protein sequence ID" value="OUO57705"/>
        <property type="gene ID" value="B5F75_00595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="406" mass="42642" checksum="7399CFDEC4BFA376" modified="2017-08-30" version="1">MKLKWGLLPGVICAIALGIGCGLFFPDWLVRAALTFNGFFGNFLGFIIPLLIVGLVAPGIAELGRSAGRLLLITTVLAYGFTLASGFFSYGVSEAVFPYLLETSSQTAQFAAAAELKPYFTVAMPPVMDVMSALVLAFTLGLGMAVIQGSRLKGIMWDFRDIIDRVIARVIIPLLPYYIFGIFLNMTVSGQVVAVLGVFAKIIVLIFVITAVMLFLQFAAAGVVAGKNPFSMLKTMSVAYMTALGTQSSAATIPVTLKQTVKLGVREEVAGFVVPLCATIHLSGSTMKIVACALAILFMSGTPMPFARFAGFICMLGITMVAAPGVPGGAIMAALGILQSMLGFSEAELGLMIALYIAMDSFGTACNVTGDGAISVIVDKIYSRRAPQAAPKMPSAPGNPQGIRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFK7</accession>
    <name>A0A1Y4DFK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56469">
        <property type="protein sequence ID" value="OUO56469"/>
        <property type="gene ID" value="B5F75_04555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="410" mass="44103" checksum="FCD0FFF551D64114" modified="2017-08-30" version="1">MKARYPFILIGVLCLSVCAGALGLTRPGQLDDAAGMPGKRGFSGDGDDALQARLGNPMGIAVDRYGNIFFSDTVNHRVRRVDARTGEIDTVVGTGKRGFDNDGGNAEMATLNGPTGLVFDSLGNLYIADTGNQRIRMFTPKGYLYTIAGDGRKGYNGNGMRPLSSSLNNPTAVAISPQGELYISDTGNNLVRKIDRRSGFLVTVAGTGDAGNSGDLDLAENAQLNKPSALVFDERGNLFIADTGNHQIRWVEPRRHLIFTIAGTGKRGFSGEGDRKCTDSAFSNPTGLAVDKLGRLYIADTDNQRIRRLTVESRMDSKVVTVVGTGERGYNGDGMDAWDADLAYPGAMVITKHDMLFFADTGNNLIRRVQGISTVEPPVKYTGYGQAQAQPDDRNFLQVLFGVKKNNTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFW7</accession>
    <name>A0A1Y4DFW7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_05085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56569">
        <property type="protein sequence ID" value="OUO56569"/>
        <property type="gene ID" value="B5F75_05085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="349" mass="37786" checksum="A67D60EFD1C01DA2" modified="2017-08-30" version="1">MEQKLDFSILKTLTELPGISGRESAVRSYLKDLLSPYADDVRTDVMGNLIFFKKGTSDKNLLLCAHMDEVGLMIHHIDERGFLRFVTVGGIDPRTLLAQRVRVHTKKGSFLGVIGTKPAHITTEADRAKAVGVKDLCIDMGLSGEEVKKRVEIGDFAVLDRTYEEFGNGLICAKALDNRAGVFVLAEVLKALKNPFYNVYAVFTVQEEVGLRGAATAAFGIEADVALCIDTTGAADIPGCAPQDYICALGQGVGITALDARTITPERLFNALKALCDEYTIRRQIRIAPRGGNDAGAVHQSKTGIPTCGLSIPTRNIHSNVEIVSKFDVGNTFRLAYLAAQNGIKEVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG68</accession>
    <name>A0A1Y4DG68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ParB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02380</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57642">
        <property type="protein sequence ID" value="OUO57642"/>
        <property type="gene ID" value="B5F75_02380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="3">
        <location>
            <begin position="39"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="33234" checksum="D24CD34366B2768B" modified="2017-08-30" version="1">MSRQALGKGLDALIKQTQEVMQMPAEAAQQAQTPGMSVTKIAINKIVPNRFQPRRVFDEEKLQELAQSIKEHGLTQPIVVVYDAGLDKYEIVVGERRFRATQLAGMTEIDAIVHKHLGDQEMCALALIENIQREDLNPIETALGYRNLMSKFYITQADLASYCGKSKAAISNALRLLDLEPEIQQALQEGSLSEGHGRALLMVTDSAKRDGLFKKMLKTKMSVRQAEAAARALMFPVKKEDKAGKPVEIASFENDLQTALGTKVEVKCGKNMKKGTLVIHYHSLDELDNIASRLKNKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG88</accession>
    <name>A0A1Y4DG88_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">B5F75_02490</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57662">
        <property type="protein sequence ID" value="OUO57662"/>
        <property type="gene ID" value="B5F75_02490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="300" mass="33585" checksum="62B0A1D4F37E15B0" modified="2017-08-30" version="1">MESLRDIRQNIKAIKSTQQIMQTMKMISSARIRRAQEAMEAARPFAKKMLEMVDDLKQDILAMPQPDEGESWEGRFFVNKTGDPRKIGLLVITGDKGLAGSFNAVILRSVLQFLKANKDKEIFVFAVGKKGRDFLARLKMPQLHLAYESVGIFPKVSYAHAELLGEAVLKTFFEQKLGSVTLIYNDFKSLASQNLVEQKILPFDFEAITKDREESDFLFEPGMLEIFKLLVPRLFKANMYRFLLESQAANLAATMNAMDAASKNAGELVTALGVKLNKVRQAGITNEILDIVNGAEALNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGI6</accession>
    <name>A0A1Y4DGI6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperonin GroEL</fullName>
            <ecNumber evidence="3">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-60</fullName>
            <shortName evidence="3">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groEL</name>
        <name evidence="3" type="synonym">groL</name>
        <name evidence="7" type="ORF">B5F75_02745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56779">
        <property type="protein sequence ID" value="OUO56779"/>
        <property type="gene ID" value="B5F75_02745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="544" mass="57718" checksum="5EDB2CF39D53438A" modified="2017-08-30" version="1">MAKQIIYGDEARAKMKSGIEKVANAVKVTLGPKGRSVVLEKKFGSPLIIDDGVTIAKDIELEDKFENMGAQLIREVASKTNDVAGDGTTTATVLANAMLTEGIKNITAGANPTLVKKGIEMAVEATKEELNKMHKPVKTKEEKAQIATISSNDREIGNMIAEAIEKVGAEGVITVEEGKTATTQLDIVEGMQFDRGYISPYFVTDSERMECVLENPYIIVTDKKISSMNELLPVLEKIVQSGKQFLIIAEDVDGEALATLVVNKLRGTLKGCAVKAPGFGDRRKEMLEDIAILTGGEVLSEERGIKLDKAELAMLGQCARVVVDKENTTIVSGKGSKEAIAARAEQIRKQIENSKSEYDKEKLQERLAKLSGGVAVISVGAATETELKAKKAKVEDAKNATKAGVEEGLVPGGGVALARCQKKLDALKADNEDIRTGINIVRKALTAPLKQIAVNAGLDGAVVVDNVLKMTGAADGYDAEKNQYCDLLKAGVVDPAKVVRTALENAASITGTVLLTETLVADAPEKEGAHAPAMPGMGGMGGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGU0</accession>
    <name>A0A1Y4DGU0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="7" type="ORF">B5F75_03330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56889">
        <property type="protein sequence ID" value="OUO56889"/>
        <property type="gene ID" value="B5F75_03330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="278"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="324"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="352" mass="37960" checksum="C3C62BE4FC7FA070" modified="2017-08-30" version="1">MSNVSMKAMLEAGVHFGHQTSRWNPKMGRFIFGERNGVHILDLQKTAKELKKACAFIKEESKKGSKFLFVGTKKQAQEAIQAEAARCGAYCIHEKWLGGTLTNFQTVKKSVERLNELEKWESSGVFKAISKKEASRLTKEMLRLQKLLGGIREMKVLPDVVFVIDPVDTAGAVRESHALGIPVVAVCDTNADPDMITLPIPGNDDAARSIKLFCSAIADSILEGKAELEAVKAAENQPAENPVMAQAFETAMLAAEKAEAAAPAAVETTVVVEETVKAEEPAKEEAKPEAEQPKAEEAAKAEKPAAKRKTAAKKPAASKAKKTVKAKAKAEAETEAEPKAEAKEEAPAEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH74</accession>
    <name>A0A1Y4DH74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NDK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56278">
        <property type="protein sequence ID" value="OUO56278"/>
        <property type="gene ID" value="B5F75_06585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NDK" evidence="2">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="17291" checksum="75A160C0018C01A8" modified="2017-08-30" version="1">MRYMERTLVLIKPDAIEKRISGLILDRLDHLGLQMTGAKVVSLTEELARAHYKNLEGKPFLEEVIQYMMGEFNNVPNHKIYAFVFQGENAIAKVRQEIGSTNPEKAAPWTIRGSFGRFIGDVMQNCVHASGSPEDAEKEIALWFKPEEVLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHQ5</accession>
    <name>A0A1Y4DHQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SMC-Scp complex subunit ScpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57209">
        <property type="protein sequence ID" value="OUO57209"/>
        <property type="gene ID" value="B5F75_00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="309"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="337"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="378" mass="40839" checksum="E0CA6E8E236803A1" modified="2017-08-30" version="1">MQTEEQLPETEQAAPVAPQEVSSAAQTPAQAAPADALQPSFAPAQPADGETAGAESAAPGQADVAANASAQPAEAASSEEPFELVPTSEFKQIVETLLFITDRPLKPSRIADVIDGVDARRVREMILEIKDDYIRRNSAVQVVELGGGFQMSTKPEYGRWVRRLYNEKMTTRLSNAALETLAIVAYKQPITRAEMEAIRGVDVAGPLERLLERSLVRVVGKKDTVGRPMVYGTTDEFLRMFGLNKISDLPDLQVFAAKSLREKQEDLPFGEPLPPLAEPAIIPVEELEGEERLEALDSSADPFFTRNSYNKGDFFGQQSPEADAFAAPDVNPAGQEPAAKPSSSEPETSPASPDGASRPEAQTAASEQTQEMSQEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHR9</accession>
    <name>A0A1Y4DHR9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56478">
        <property type="protein sequence ID" value="OUO56478"/>
        <property type="gene ID" value="B5F75_04600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012960744" evidence="2">
        <location>
            <begin position="24"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="15939" checksum="A2D095F083634D3A" modified="2017-08-30" version="1">MKKLLLAAVVAVFGAAACSSGNANTKTADGRTASSSKNAKYQIIDQEFDNLLAPDADYDTIPDYELQACGDSYLPPATTPLKGATKPAVRKPAKQAASSASTAKSSDVNVNKKVINNTNIYYLDGSAPNTSTTSTTTYTSEEALPPADVPDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHW1</accession>
    <name>A0A1Y4DHW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56528">
        <property type="protein sequence ID" value="OUO56528"/>
        <property type="gene ID" value="B5F75_04870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032810">
        <property type="entry name" value="CCA-adding_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13735">
        <property type="entry name" value="tRNA_NucTran2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="5">
        <location>
            <begin position="251"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="499" mass="56203" checksum="B5F0EC92EE933C25" modified="2017-08-30" version="1">MLELAQILKEVMPQAHYVGGIVRSSLLRRPSSDIDITLPAADVPAAAKALGRRLKAAVFEMDAELGVWRVVTHKEKIQIDLTAYQGKDLKADLLRRDFTFNALAYPVAALPQIVITPRKNETAHILLKKIRRKEIVDFSHGLDDLAAKVIDRNHPHVFKDDPLRMLRAFRSAAELGFTISKRTLLQIKKDHALIVRSAGERVHEELDRLFATSKAYENLRVMDQCGLLTALFPELEAQRTCAEVYYGKGGVLKHTLAVFQRMEYLLDHLAKAFPKYAKKLAPYARNKPLYKMAALLHDIAKPATAKVMGDRLRFFYHEEQGAKMAKTVLERLHYSRADMRLICAMIGEHLRPSNLASNDVITDRGAYHFFRDLGEAALPMLLLCWADYASYVTDAQLRRIMPKSALPMMTIAQAQKTANIGKTLRHMQVLSLLFKKFFDTPKKIAPARLITGRDVMDALSLPPSPKIGAILEAVSLAQVEGKVRSKEDALAFIRQLPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI63</accession>
    <name>A0A1Y4DI63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00825</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57349">
        <property type="protein sequence ID" value="OUO57349"/>
        <property type="gene ID" value="B5F75_00825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="258" mass="27570" checksum="078385CBE1E682DE" modified="2017-08-30" version="1">MFTAIGTYMTRMFDQIGGAAQMVRSSLFWLTHSRFEFRQAVDQSVTIGVESLGVTALTSLFTGMVLALQAGNTIGNIFGEPIFVGTIVTFSLIRELGPVLTSVVVSGRAGAAVTAQIGTMAVTEQIDALYTLGTNPIRYLVIPRMFGFMLTMPILTLFSNLFGVLGGYLVAVYALGIAGEVYITDITSFMGVRDFMHGFIKTFVFAFMVATVCCYKGISTRGGAEGVGKSTTGAVVTTIVLILVLDYFLTAILTAFGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIH9</accession>
    <name>A0A1Y4DIH9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01470</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57469">
        <property type="protein sequence ID" value="OUO57469"/>
        <property type="gene ID" value="B5F75_01470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="185" mass="20490" checksum="B545B4915C0A46FB" modified="2017-08-30" version="1">MGIIAVTIIFLCICVDNMVSSNMSAMKMTPEKKSVFSIKMALFFAGFNALFFGIGYLLSILFFHDWVHFANNWIAFAFILLLGIKFMLESIEKSPSFSNIDVDDNKKMVKVSSVIGLNSLLVGYAVETMDKSFFPQVLILIIITFALTLLGFHLGSRTSKVVTSKKIELIAGLVLIVMAVSQIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIP3</accession>
    <name>A0A1Y4DIP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57539">
        <property type="protein sequence ID" value="OUO57539"/>
        <property type="gene ID" value="B5F75_01835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="4">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="263" mass="28031" checksum="AFAC9F36ECF2DEF0" modified="2017-08-30" version="1">MQIDRITCVCFSATGLTQKTADLFTDAFGAPVKKVDITPFSAEDVSLSFGPSELVVFAAPVYGGRIPAAAARRLSHLKGNHTPAVVLAVYGNRDYDDALLEMQDIALAGGFVPVAAAAPVAQHSLMPRVAKGRPDEKDASLLAAFAKRVQQYLRQADAQELTVPSVKGKRPYQAYPKIPFQPSASSACVKCGVCAQACPTGAISLENPSQTDASRCISCMRCVAVCPHHARGINKLLQGVAQAAFLLKYGARKEPEFYCNDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIR6</accession>
    <name>A0A1Y4DIR6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Autotransporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57559">
        <property type="protein sequence ID" value="OUO57559"/>
        <property type="gene ID" value="B5F75_01945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012689323" description="Autotransporter domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="3">
        <location>
            <begin position="779"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1032" mass="109473" checksum="5AC6B18622F6CA5F" modified="2017-08-30" version="1">MKNLTAGLILAFCFASAANAQTWKPIETAGPVEGETVTINKPLTQEATNMMIAGGASMNATATNNTLNISTDIAETNTTVPEGQYNHYIAGGAVYNNTADGNTVNISGANISGRAVAGGLARTNRADAVDAEKWNTGNATNNTVNITGATINVNPQTADSVFDMEGDPVAVAGGASQFFIGNASGNTVNITDSAITGGVVGGLSYVKTSQEEVDNHPDITADRNNNNNTVNLTGSTVTGDIYGSLGGVTGNYNTVILNKTTVNGSAFAAKSGFSLYDGEQSVGTFDYNRLDLLNGSRVQSAAAVSAANNNASHNIMNIQDSTVADGTLYTVKMIHGQEDNSSTIGGTTDYNTLTITNTPMTAYEIGGAVNFTGNPSHNTVSISGSDLTLTYNGNDTLGGVMNIQSLTSQELLGTKTSLDNPISPVLNTSHGYILGGATSDYTSQTNTEPTEEAPEEFILGFGSAADNNTISLQNGTINANVMGGFASYVREVNYTTQQTDEKGRVTEKVEVSKTGLTTTTTTTSYTYNEETGEVTTQTSTDTDTAEQIDDKFSASGNTIMLTDVTVNGNVYGGYVDGAELKQENMLAQNNTVVLAGNTQVNGTVYGGSNPYYANTNKLVFSHIANGNNFVSFDMNNFKNFNPMTSIYGDFDTRLEFTGGDVHAQMTLASSAMKETDATVIIRTPGDILDGYGPVECNGDPNCIKYTSDVALTNNKLGAYSFTLTPDLQGNVLEWTLASRKDKANVEMYGQLPLVGLALVSEGPEMLNQTMNDIWQSDTDQNSFVNAAYHHTRYKTGSGFDLDSSVVHAGAWKKFTDDWVLGFFAKYAGGSYDTFPIKVSGDANAAGGGLMTSLRYSETGRLEISAEAGYMDIDFNSSELLSSFSSKGLYYGATAGFVENLLPDLDLFANIQWLRKEKDDMTDNLNQKIEFDSMQSLALRFGADYTFTSVDLGGLTPALGVSGLYEMDGESTVAVDGMTNSDASLKGMSGRGEFSLIYHNNDTFLPLHTVLTLYGQVGKREGFGGEVNISFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIS2</accession>
    <name>A0A1Y4DIS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_02000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57569">
        <property type="protein sequence ID" value="OUO57569"/>
        <property type="gene ID" value="B5F75_02000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004700">
        <property type="entry name" value="PTS_IIC_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03609">
        <property type="entry name" value="EII-Sor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="22373" checksum="2A01658134861CCC" modified="2017-08-30" version="1">MMTPEVFMLCVLAALLELDTTYAFQLTFSRGIIAAPLMSLLTGDIMAGIQVGVFTELIFADINPLGGILPPSAVVCSAVSLALHALGIDLYFAFFFGVGGAILFSLAEKLMRKNRFKWLVFWEQKITKTPSAVNRTVALALATSFLMNFILIFIFTWICGKLMLWLLPYIPVKAQFACKFAYMAVPWIGLATLVPAFRLKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIS8</accession>
    <name>A0A1Y4DIS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56220">
        <property type="protein sequence ID" value="OUO56220"/>
        <property type="gene ID" value="B5F75_06270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011988722" evidence="1">
        <location>
            <begin position="18"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="185" mass="21229" checksum="58FF8AFDB11E8FC8" modified="2017-08-30" version="1">MKKMLGLLFVSSFILLAGCQAQKEESPYNRTNPKQDYERLLRTHVFAACQNPGKPYALYSLATLNKRPSDNDPRYKVTFFNGPCEGQTVWTTDVLLKTAAVGAEPLPKGTVLLRNFWNPKDPYDTEKADRWHIGVVSSSQRLDKGIVDMEFPRDRNDFMPAREGVYLHNVRYITKPEVKDVRTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIU3</accession>
    <name>A0A1Y4DIU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56240">
        <property type="protein sequence ID" value="OUO56240"/>
        <property type="gene ID" value="B5F75_06375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012960740" evidence="1">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="149" mass="15898" checksum="B26D72D13CE0D9F0" modified="2017-08-30" version="1">MKKVLALFALLCCLVGCSGTMKSAVKDGAIAPSFNDTLLDSNYLWVRGFGAANPAHTSDSQRRIMSREAAIAHAYQRATEVLFGANLESNVQVVDAVSSGSTIDTSAHGVISQMELVSTEYMDDGGCAVIMRLDRKRLQAAGINLEGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJK0</accession>
    <name>A0A1Y4DJK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56500">
        <property type="protein sequence ID" value="OUO56500"/>
        <property type="gene ID" value="B5F75_04715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="18853" checksum="8AB8642B3CAE37F5" modified="2017-08-30" version="1">MKKPEKHLFQKGFTLIELLTVVLIIGVLMAVALPNYTRSIERARAVEAMAGIKALNDAVYAYAAGRTGLNACPRSFKKLAISFPGHLSADESTIETKDFEFIIHSASNAIIPGTDCPGVVARRLGGQKYQYRIWNPYVRGTGGKGASLACTGPNESSIEICKSLDLYKEGVTPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK57</accession>
    <name>A0A1Y4DK57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57318">
        <property type="protein sequence ID" value="OUO57318"/>
        <property type="gene ID" value="B5F75_00645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="488" mass="53306" checksum="93AB25939BD456D9" modified="2017-08-30" version="1">MSKILSKIKLNTFAIILSIVAVVAVLTWIVPSGAYDKMDVDGRQVVVAGTYHPVPANPQGLFDVLKAPIQGFSNTAEVIVFLLVIGGVLAVVEKTGAIAAGIQAASGFFQRKPHLRFMFIPLGIIVFSLCGATFGMCEEALIFIPIFIPLALSLGYDSALGTAIPFIGAGVGFAAAFTNPFTVGIAQGIAQVPLYSGIGYRFIIWIICTTVVITWLSVYARKIRKDPTKSLTYEFDIEKRKELKLNKEETRMTRRQKWVLVAFGLGMLTLIAGVLKPQLCSMIKGMWGVDLMQMLHLEASGWYITEIAALFLGVGFLCGFLGKMSMQKFTDAFFDGVRGMAEIAMLLCFAQAIVIIANNGHILDTLLNWMSGAISRLHPVCASWAAMVLQTVIDFFIPSGSGKAVLTMPILAPLADLIGITRQTMVLAFQLGGSWMNMVIPTDPVTIAAIGFARIAYPKWLKWMLPLLAVMYLLSFVLLIPPYLMKWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKA0</accession>
    <name>A0A1Y4DKA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57348">
        <property type="protein sequence ID" value="OUO57348"/>
        <property type="gene ID" value="B5F75_00820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="254" mass="27777" checksum="4172827894E1B9DA" modified="2017-08-30" version="1">MIEIIGLKKSFGTKEVLKNVNLKIEEGKTTCILGGSGSGKSTLIKCLIGLEQATGGQILVGGKDITKIRSEIKLAALRRRFGYLFQEGALFDSMTVGENVTFGLKYLTDTPEKDYPAVSKEKLALVGLQEDVAKLNPSELSGGMKKRVALARVLAVEPQVILYDEPTTGLDPIMSDIISDLIMDLKAKLGVTSVVITHDMHSAFKIADYIAFLYEGDILMYGTPEEFKHTDNPYVKQFVTGSSHGPIQMKLMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKQ5</accession>
    <name>A0A1Y4DKQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnc</name>
        <name evidence="10" type="ORF">B5F75_03280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56880">
        <property type="protein sequence ID" value="OUO56880"/>
        <property type="gene ID" value="B5F75_03280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="154"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="224" mass="24923" checksum="09A7FB412D4EDDEC" modified="2017-08-30" version="1">MIVYTDIEHIIGYCFKDKAVLKEALTHKSFAGEHRSAKHNERLEFLGDSILGAIVADYIYNQCPHVEEGVLSKIKSNLVSRRNLYLWGKQMDLGRYMSLGHGELATGGRERDSIISNAVEAVIGAVYIDGGYPAAEAMILPWVKTQALTQDAQDFKSVLQEFLQKRGQHTPVYEVIQTVGPEHDKTFTVRVSLGEKELGVGKGRNKKLAEQSAAHAALEQLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKT0</accession>
    <name>A0A1Y4DKT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57538">
        <property type="protein sequence ID" value="OUO57538"/>
        <property type="gene ID" value="B5F75_01830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012056763" evidence="2">
        <location>
            <begin position="22"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="412" mass="47062" checksum="0352C5A18A139E9A" modified="2017-08-30" version="1">MKKFSALLLSVLCMTPFLANARPLRQVSDTTSRQAAISRAIFQQQNDYNKQKQASSDDSFAQAQQALNQLIQQNKETVSLSWEDFIEKNKQAQQRARQELQETEEELTQAFSDSNASFKFEGKNTPIDYAKILSGIKLIYIGESHGSEDVPLEVMTLLRTVRQNNPNARILLASEFALRQEATDPYIKKAGTADPWRKSYPALFQTADELNIDQLSLDDQIFTIDKQKDGFYLGTKIGAYEVTVPGGQDISDSTFPYMVLATHYKIHASTWGVAERNRQWARYINAVKPFYDVIVVHCGMGHLIETTSTDLLVQIHMPPAALFLYFPMKEQYSEVLKKYADMYDSHLRKENLMDPMFITEETAKLLREKTGMSLQEWKDFSKPLWFMFESEGKNPNSTVPKVSLSVYLPILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKY9</accession>
    <name>A0A1Y4DKY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56960">
        <property type="protein sequence ID" value="OUO56960"/>
        <property type="gene ID" value="B5F75_03695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="211" mass="23983" checksum="50E2DE4BA89C17E5" modified="2017-08-30" version="1">MRKIKRFKIASRQREILRKLLRELPLLRRAGFTSEAEVTAFILAIFKLLDPGVVYEFNQDAHWELDDQNVLYKEMFSACAVTLGGQLEPFLNNITNEDRKTAAMIVILEFLRSAVTFVAELVKEQAQKEECETLDLQFVYLPPFGAAAAPKLLREAVRLEPVLAQKALPVILQNLNAEKIDLSVTADGELTPRISTVFLVPWQKSRKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKZ8</accession>
    <name>A0A1Y4DKZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56970">
        <property type="protein sequence ID" value="OUO56970"/>
        <property type="gene ID" value="B5F75_03745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013164469" evidence="2">
        <location>
            <begin position="20"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="524" mass="57963" checksum="622549A5848C6D89" modified="2017-08-30" version="1">MKKSLLFLMSFSVALSVSAQQPSTAPAVSPSIQVSTAVQTPQSNIDLLKQSLQTSSNVMGTASSIEVPPPAPMPVSQPPAASSTTLDMPLEMGGTVQSVQTTVAAPAKQLSPAAAKRVQQAKEKRAQAAQAKPTALEKDIEKSNALLPASQQQASSSEETEELSPEEAAAEAELEYAVKMLEKSKEALQTAGRSIPPSAAQNRPKTVPAPNKKFDPNAYRPGVTWVLSKSTHFDIYTQKRSTGISSSNMSMTFESAYQTLRRFIPWMMSGRVRVFVYQDHQSYLRYEPNAKAWTRAMAYPTRGEIVVYDEPGKTQELKEVFTHELTHIFTQQFFDSHKTGRIMTPTWLDEGLAVLLEDQAYNGLKGGPWNNDFKTLNFQRDPSTEVASFGSSSMFGSAKKLTAKKPGKPLYLVPFAEFMEEGSLNAAEGRGKTQDWYFQAYLMVRFLLNPAGGASPSNRMQFEQFTRLLSEGEAVRNPSTGFLVKDSRGKTVYQPYSVEKALGRAYRYNSIANFEDNFWRWADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL28</accession>
    <name>A0A1Y4DL28_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57000">
        <property type="protein sequence ID" value="OUO57000"/>
        <property type="gene ID" value="B5F75_03895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018704">
        <property type="entry name" value="TPR_21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09976">
        <property type="entry name" value="TPR_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPR_21" evidence="4">
        <location>
            <begin position="101"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="3">
        <location>
            <begin position="543"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="826" mass="91866" checksum="A29D6F677E862582" modified="2017-08-30" version="1">MPGGVFRPRTGRFPSRMKTRHMAWTNGFNLRERVFYPLLFFVRETIPGKRSAQKIAAPCRGGPARPRQNRGKHLPCLEPPGKKRAPCVRRGKGGVFAGPIWYNLYMKKCLLLSVILGVAAGLPGLAWGAAETAADNAASEEEAVQTVSKSTLAATRVDSKLNETVLHKSVLDYYLPADIAAVAKKCAAGEIDECYFSFKTFENASDAKTAAAANLELAVLSLQRGLVKQAVKYIDQACAFNPDDPFAELTRGWILLSSGKYKKARKSFQDLLYLTADFEYVSSAKLGTALAWYLDGDKEKAATELQYLYTSNPYTISFVSYMLGRIASEMKSSRKLAPVFLQQSLTHDARNYAAVELFAQLSEKEKNDLRAWQYYATLYSLDPDNKDLAKKIEKYAKKLGDKSIDYLFYLRLEQPIVHEMLSTPSEKVKMALYANREQIPQELLSFSLMPSGTMRVEDEKLGEVLRSPSYIQKTIVFNPQTGGVDFTNDKGHVEFSAKRPFTVTVENPNKTLLVREATAQNIFAADLSDKELKGTLIVIPTPQGIKLVNEVYAEDLIPALLATQVQDITHDSALKALAVVFRSALLQAVQDHQDQPYHITDNDLHFKFKGINLIFKNLLDASKESAKIRLTEAQAGAYADCGVLTADSLENTADKPGYIFSPANVSKYLLSNPPADLYSRPQDPTQWAGIKWMYLYDGKEIENRIAYKQNIGKLRALTPTSFTEKGRILSMRFEGSKGSYEAKTPQEVAFILSAGTMRSNLFDIVPFYKGKNIKSVLVRGYDTGLGYGLCLQGADGLAKQGADYMAIIKYYFPQARILDTTTGTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL52</accession>
    <name>A0A1Y4DL52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57030">
        <property type="protein sequence ID" value="OUO57030"/>
        <property type="gene ID" value="B5F75_04070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020991">
        <property type="entry name" value="Connector_podovirus"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12236">
        <property type="entry name" value="Head-tail_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="533" mass="59406" checksum="D0545AE9A92ABF64" modified="2017-08-30" version="1">MKHNTQQTTDYLRLYDELKSERASWTPAWKELSAYLAPTRGFFDGQTPNQGRRIDHKTLLDSDPCLAVEVLCAGMMSGLTSPSRSWFDLTLAPEELMNLPGAREWMFEIKKRLEDVFAKSNVYSVLHGFYQEISVFGTAAFLVEEDPQKGIRCRPFTIGEYALGTDAAGRVNRFGREFFMTAEQMKDTFGPEHLPPAVARECDENRTFRWHKIIHLILPNPAQNPARQDSAHMPYLSVYLTDNGHLLRQSGYREFPVIAARWEVKNASDVYGRGPGWKCLGDVKMLQKMQKTKLVALDKSTNPPMMVSSNVQGEVNLLPGGITRYNGTTDAAVKPAYEVQPDLKSLEASIQSVRDTIRAQFFADVFLMLSTQNYSNMTAAEVAERHQEKLLVLGPVLERLKNELLDPLIDRAFNLLFRQGLLPPPPQSIEGLEMEVEYVSMIAQAQKAAGLSALVKGLNYAASLAASRPEVLDRVDYDRALEEGLTTLGVAPALLRSEQETRQIRAERMQAAQQLAAAAQAPAAAGAAPSPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLD1</accession>
    <name>A0A1Y4DLD1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56221">
        <property type="protein sequence ID" value="OUO56221"/>
        <property type="gene ID" value="B5F75_06275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825082" evidence="1">
        <location>
            <begin position="22"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="27449" checksum="D8230BADE496BA32" modified="2017-08-30" version="1">MNIKKLIALVCCAFYPLALQAAPGDPISLETMIIDVPTAETFDRYQASFLTRAYDHGTLMESIDFGVFPRINIGVSIAAHELVGSSNDVRVLDPDFQVKWKVYDGNLYLPAIAIGYDGRRYGYGYNDQRIYTDSKDYLDDRKGGYVTFSREIIVPGLNATAGLNLSDWEDLYWFTGMYYTLADKVSFLAEWDNIRNVRDSRLNIGMRFYLHPSLALDGAVRRIGRGDESERILQIRYVTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLT5</accession>
    <name>A0A1Y4DLT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57260">
        <property type="protein sequence ID" value="OUO57260"/>
        <property type="gene ID" value="B5F75_00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013142040" evidence="1">
        <location>
            <begin position="19"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="23741" checksum="A491C3F9DC242FE7" modified="2017-08-30" version="1">MFKRILTFSLAVLLAACAGGRVKEIPADVRDYRKVDFFTQGRTQAAFKVLGQMDQDYMEGVLRIKKIGERDYDVVLMTGAAYRVLHATVSPEGVAYRYLFKEADTPLVRGRITQFLNLLLAEEGQFKSRRFKGENVIVTYQGREAKEQFFYRKGEFYPYAAKSVVALNTGDLAYEEYAPFDAEGTTEVPHVVVYKDGNVTLDMTLISLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLV4</accession>
    <name>A0A1Y4DLV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57280">
        <property type="protein sequence ID" value="OUO57280"/>
        <property type="gene ID" value="B5F75_00435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011567" evidence="1">
        <location>
            <begin position="25"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="304" mass="35499" checksum="43F812FB4F28A53C" modified="2017-08-30" version="1">MYNKKMKHLFALFLLSVCWLSGQADSLPTNQEDKPKYTEAVVYSRFRGFNMPKPDENNAYVLGEFTYGNEWTDYFIRENNLYFNWSGTLYFHLIPADPFPILESFQLWQDNYQEFEKQFLAEFAVPHLDGKNFSLPCGKNSSVEFIKQIKKGAPGEESDVFYKVIWHKDGKQHTFTREECPVPVIDFPPGQFAYCDENILYYDGFDDFPWPGRNKARRGIFFCDLQNHTRGAYAATPYETKEKSALYPYNPIGIPGTNWIFYLQDSDESPRKSQLVVRPKLTPAQAEKAAQEYQKFIQSNTKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMF6</accession>
    <name>A0A1Y4DMF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56581">
        <property type="protein sequence ID" value="OUO56581"/>
        <property type="gene ID" value="B5F75_05150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012757033" evidence="1">
        <location>
            <begin position="26"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="313" mass="34219" checksum="F2BF458AFB3AE1A3" modified="2017-08-30" version="1">MKRGKKLYIVLFCAALFFVSLPLSAQTNKKVVKSIVNNAGKTASEQIAKTAASAQAQKLAQIPQAGSSAAVQSAANSLQKDKPTLSVQVNPTVARFVNRNKKLLYGLQKSVGISSHKAVENLYRWGAKPLKKPQRPGLLKEQTFTVQDFAELKYTRGVVPVLPFGYHAKYMYRGLGLALNGKAVRNILENGLLIKDVSPRNNDRRMAYASAGGLGAMKAILRESVINLTDSPVMALHYAWRNKDKGMVVLVAVKEELNRGGVITVPNDIPADKIGEMVALLQVHGKPTWCRIELAPEGFRVTPYSSPKQTKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMQ8</accession>
    <name>A0A1Y4DMQ8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">B5F75_02165</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57600">
        <property type="protein sequence ID" value="OUO57600"/>
        <property type="gene ID" value="B5F75_02165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="39"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="398"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="701"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="461"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OUO57600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="794" mass="87108" checksum="59E8365515D2940B" modified="2017-08-30" version="1">MKILYSWLKDFIDLDLTPEELSKKLTDVGIEVASVETTGADFEGVFVAQIIKIEDHPNSDHLHLVTLDLGSGKTQRVVCGAPNVAVGQKVPLARVGARLGKNVLKPAVIRGVESEGMICSSDELGLTQTRARGIMVLDENLPLGTDVSSLYGKPDSLFDLEITSNRPDLLSHLGVARELGVLLNKPVKLPAVKAVKGEGKALEVEIQNAEGCPRYTGRIIRGVKNTQSPEWMKQRLAAMGLNPKNALVDVTNYVMFELGHPLHAFDLREVEGGKIIVRNAQEGEKFTLLGGRELTLNANCLMIADAHKATALAGIMGGLNSGIKDDTQDIFIEAAYFNPPTVNKTVKKFAVSSDSSQRFERGTDIEGVTLAMQRATDLFLELCGGSASEVVDVYPSRYESPTVVFTPAEINAILGAQIPEEKLKEIFGRLAAEFHADGEKWTFKAPTHRRDLNHKWDLAEEAARFAGYDMIPVSETKASLAFADNPKGIDLGKKYARALIGAGFCECKNIDFLGEKELKAFGVEPKNCIKIKNALAQGWDYLRPTLLPSLLKNVESNLRFGNRNLALFETTKTFQSIKGFPVEGYAVAGVLTGSLEQEKFFGGAEKPVDFYWLKGLLQALLADVEGVAFLPSKTAPVYMHPKICMDILLNGKVIGVFGKVHPLTLKAFDIKTQDVWAFEFATKLIEKAFSAQDFKPAKEVAVFPPSLRDLSVVLDESVSYASITSALDKTPLDVQLEYHLIDLYQGEHLPAGKKSVTFSLAFSNPQRTLKDKETDEAFNRIVQQLREQVGAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMT4</accession>
    <name>A0A1Y4DMT4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvoyl-dependent arginine decarboxylase AaxB</fullName>
            <ecNumber evidence="4">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvoyl-dependent arginine decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57630">
        <property type="protein sequence ID" value="OUO57630"/>
        <property type="gene ID" value="B5F75_02315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01404">
        <property type="entry name" value="PvlArgDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016104">
        <property type="entry name" value="Pyr-dep_his/arg-deCO2ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016105">
        <property type="entry name" value="Pyr-dep_his/arg-deCO2ase_sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002724">
        <property type="entry name" value="Pyruvoyl-dep_arg_deCO2ase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40438">
        <property type="entry name" value="PTHR40438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01862">
        <property type="entry name" value="PvlArgDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005216">
        <property type="entry name" value="Pyruvoyl-dep_arg_deCO2ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01170">
        <property type="entry name" value="Pyruvoyl-dependent_arginine_de"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56271">
        <property type="entry name" value="SSF56271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00286">
        <property type="entry name" value="TIGR00286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20338" checksum="D4761F395F89DBFE" modified="2017-08-30" version="1">MYEAFVPKEIFLTKGIGRHKEKLASFEEALRDAKIASFNLVPVSSIFPPGCKTVPISKGLQELHPGQILHCVISRNTSNEYRRLISASVGLAIPKEGKKTHGYISEHHSFGETDKQAGDYAEDLAALMLSTTLGIEFDNNTTWDQKEEIWKMSGKIVRTTNITQSAICVEGLWTTVVAAAVFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN00</accession>
    <name>A0A1Y4DN00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56781">
        <property type="protein sequence ID" value="OUO56781"/>
        <property type="gene ID" value="B5F75_02755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="274" mass="30198" checksum="5AD995F1E6916FAF" modified="2017-08-30" version="1">MSSFDIEFAAVTDIGKIREKNEDNVLISSDLGLGVVADGMGGHSAGEIASNIAVSVLAETIRKVNNQQLKIPDNFLPKLDPVERKLLMAANLANAAIYSTAQSSDIYRMMGTTLTGVLFDKDCATAVHVGDSRLYLFRDNKIVQITTDHSLAMEHVRRGLLTRAEADHSKIQNVLTRAMGIKKNIEFDLLKFPVKVGDMLLLCSDGLYKGLRECDMAAMLAQGQQTPIVKLCKQLVRVSNENDGQDNISAVLIKILPAQKMSFKQRLRRFFSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNE6</accession>
    <name>A0A1Y4DNE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56921">
        <property type="protein sequence ID" value="OUO56921"/>
        <property type="gene ID" value="B5F75_03500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="80"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="257" mass="28816" checksum="336B8E25DEB45A5F" modified="2017-08-30" version="1">MIYGLYTAAGLLAALCIYFLLRRRPHALFVLAYEKAGAAPKHSSLKGEWISPQVFGRHLNWLSKHGFTVISLQTLSSARRLPAKPVVLAFLGGYQSFFTQIFPMLKQANTPVAVFLPPALADAYNAWQDPHREPWQNLLTENQIKEMQKSGLIDFGALCENGEDLTLLPLQQAAGLLQESAAVMQIRLKLKPKGFAFWPAARFTLKKASRLLPEGFGGLVLTPLEGPNKRTGKKLFLKVLFPARRPLAVRWALWKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNF4</accession>
    <name>A0A1Y4DNF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56931">
        <property type="protein sequence ID" value="OUO56931"/>
        <property type="gene ID" value="B5F75_03550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="18667" checksum="D1FFF64F3F5C6029" modified="2017-08-30" version="1">MKRNHTGFTLIELLAVVMIIAMLTSVALPQYRKSVQRAESMEALVNLRTIFDAAKRYRSANSEAPMKLNGLDVSFFDADTPEASSFNIGNYHYAFSDWGVSACRISGSGSYANTYCLDMYYTYRLGDTKYKDLLICASKSQKYSWLCDSLKTDELPDGTAVIGTELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPA4</accession>
    <name>A0A1Y4DPA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4422 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57221">
        <property type="protein sequence ID" value="OUO57221"/>
        <property type="gene ID" value="B5F75_00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025536">
        <property type="entry name" value="DUF4422"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14393">
        <property type="entry name" value="DUF4422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4422" evidence="1">
        <location>
            <begin position="9"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="638" mass="74994" checksum="ED217DF7799F9A9D" modified="2017-08-30" version="1">MNTNNPTIKLLISYHDKHRLLKSDILTPIQTGCALAAERFEGMLQDDDGENISTGNPQYNELTAQYWAWKNYAKLGNPDYIGFMHYRRHFCFDESLIGQQSTWLSASCVYKMPSATDDYLNRNFHPQKISNSLKGYDCLVLKAYDVTNLGSSSNRHHYATGIPEQNVATFDLLLETVLKFFPNYEEEVNSLKNGSEQYLCNMFIMKKDLFFQYCQFLFTVLAEMAKQVDSSHFTSQQNRFLGYMGEYLLSLFIKHAYRTHSFRIKEINGFFIEDTGCSYDIKPVYKTPFSAIVMACSREYIPYLSVCLQSLVEHAHISSNYDIVVMERDIPAEEKGRLKRQIERKNVSLRFLTVPDLLADKQKIKIKQLPESYYRLFAPLLLQGYERIIYTDCDVIFNDDIAKLDQISCPTAIAACRDVMMNARLGLTWADWKRYCREDLDLKNVYDYCNAGVIVVNVTQYIKENIAFKVLKLLTSKAFRGSVQDALNSIVKNEITYLDPAWNWPTLQMHMKRMQFLSAMDCHTLNLYTHVRQLPRIIHYASFRKPWYYLQEDMAEIWWGYARKTPYYEEICLRLNQHETSKIFSCRYKNRHQNYALLYLSYLYYKLMTHITSGKKQARYKTAWVEAKNEVELWREHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPB6</accession>
    <name>A0A1Y4DPB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pirin_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57231">
        <property type="protein sequence ID" value="OUO57231"/>
        <property type="gene ID" value="B5F75_00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin_C" evidence="1">
        <location>
            <begin position="153"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="243" mass="26773" checksum="D5BAFFAB5D52A34B" modified="2017-08-30" version="1">MVLRRLIDRHNQASFDPFYWLAVCYCSPEFERADIIAPPSHPNRETLNYLVTGLVDPPDLEDEHLARPEGASRWVNVVGGLQQADPSQSVYVLNMELWMHTLPGAAGGGKRWEFESEHVPLVRTEDAQVRVLCGAFKHRQGSIAQHPLGTTILDVTLNPGGAFTYKAPAENTTVLYIFGGKVYFGEGAQVCFGKDSFLRMCGGEIMASSLASGGRFLLFSAKPIAHKKPAVCPENEEVCPIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ18</accession>
    <name>A0A1Y4DQ18_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57461">
        <property type="protein sequence ID" value="OUO57461"/>
        <property type="gene ID" value="B5F75_01425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="315" mass="34513" checksum="2E03F793C3581693" modified="2017-08-30" version="1">MLNWKGFLYAVITSATFGLIPLFTLPLLREGMNIPSILFYRFFIAVLMLGLLAFFTRRSLRVTKNELGVLAGLSLLYIGSAVFLFWSYHYLASGIATTMMFLYPVFVALIMIYVFKEKNSFWTMLAIGLAVAGVALLSWNGKAGGVSFRGILLAVLSGFSYGIYIIAVNKSSVRNMSSDKLTFYVFLFTALFLLAGAGSMGWLQPAPGWKSDLNLTFLALIPTVVSNLTLVLAIKEIGSTFCSVLGAMEPVTAMTVGVWVFGEPFTRSTAWGVALIILAVTLVVLAPALEKGYRTGKFLYITKVKGIHPNIVPYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ59</accession>
    <name>A0A1Y4DQ59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_01640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57501">
        <property type="protein sequence ID" value="OUO57501"/>
        <property type="gene ID" value="B5F75_01640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="696"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="724"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="2"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="765"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="831" mass="87823" checksum="854A53606A655A7A" modified="2017-08-30" version="1">MKKKFNVTGMTCSACQAHVERAVARLPGMRSAAVNLLQNTLTADYDEERLSTQDIIAAVRGAGYDAFAPGEETGVLSPQRAAKDEARRIKYRFIASLIFLLPLLYVAMGQMLALPLPKELTENPGLFALTQFLLVLPVLSVNRRFFTNGFKRLVQGGPNMDSLIALGSGAAVLSGLWGLFRILVLMEHPDWTAALEQAFHGLYFESAAMILTLVTLGKWLEARAKVKTSDAISALVRLVPQEASVLRDGKEVSVPVQGLVPGDIVVVRAGERIAADGVVVDGGGAADESALTGESVPQDKPIGAELAAGTLLASGYVELKVARTGKDTVLAQIITLVEEAAGSKAPIARLADRVSAVFVPTVIAIALLTLVVWLAQGTSFSFALSSAIAVLVISCPCALGLATPTAIMVGTGSAARQGILVKSAAALERAHKVTTVVLDKTGTVTSGRMQVAGIVPGAQSSSEELLTQAASLEHFSQHPFAQALSGYAEEKNIPLVPVSRFEGIPGRGVCAQEGEEQLSGGNLTYMQELGVAVADGEKLLAQEAALGRTPLFFVRGKKYLGMISFSDTIKPASADAVGLLKRMHLQVILLTGDNPQTAQSVARAVGIDRVIAGVLPQEKEAVIRRLQDEGEVVAMAGDGVNDAPALVRADVGMALGAGTDVAVESADIVLMKDDLTGVATALQLSRAVLRNIKENLFWAFIYNVLGIPLAAGVLYLPFGWKLSPMFAAAAMSLSSVCVVTNALRLRFFKPARIARKHQHKGKIMRKTLIIEGMVCAHCAGRVERALNSIPGVQAKVDLSQKCAVVESHAQITDEALKQAVQKAGYEVVAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ72</accession>
    <name>A0A1Y4DQ72_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57511">
        <property type="protein sequence ID" value="OUO57511"/>
        <property type="gene ID" value="B5F75_01695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="479" mass="53531" checksum="642F3E01F0B3A25B" modified="2017-08-30" version="1">MHIDPISASSFGIAGFLFLVLQILVTGHIICRKDDVKSSFGWIGLVWLAPLVGCIVYIVFGINRIRRKALSLRNKGPDIFTVTGKTEEEIEKEIPKPFLQLLRLGYKVHPQRFALGNRAQAFVNGDSAYPEMCRLIASAQKEVLMQSYIFDNDRAGKMFVDAFKQAVQNGAKVKVLVDGVGLNYSKPTIASVLRHMRGVEFSVFLPSKSPVNLPFVNLRNHRKILIVDGRAAFFGGMNVAEGNLVNTHPKEPIVDITFRVEGPVVDQMSRVFEEDWIFSGKKHFIPASFQVSAPLPGTMPARVIPDGPDGDYGKIELMVLGALACAQKSVKVVTPYFLPESNILTALEVVAMRGVDVEIILPSKSNIFGMDGAMRSNFARLLKKGVKIFRTQPPFDHSKIMLVDDAWLFIGSANWDVRSFKLNFECNMECMDKQLAREVNQIIAHKKATAVSEKWDKNAKPSLWRTLADNTLRLLTPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQQ0</accession>
    <name>A0A1Y4DQQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">B5F75_00270</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57701">
        <property type="protein sequence ID" value="OUO57701"/>
        <property type="gene ID" value="B5F75_00270"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="202"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="225" mass="23885" checksum="BC0D1709F8C6B90C" modified="2017-08-30" version="1">MPAANGKISVAPSILSADLWRLGEEVQKVQKAGADWLHIDVMDGHFVPNLSFGPSVVSSLKGKTDLPLDVHLMVEEPMLFVEPFANAGADLLTVHIEAKDEIPAVLEVIKKLGIKAGVSIKPNTDPGVLEPLLDGLDLILVMSVYPGFGGQIFLPESEGQIKRVRDLIVRSGRNIWLEVDGGINPQTAPLAVQAGADALVAGSAIFKAADPVLALKQIRQAAPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA05</accession>
    <name>A0A1Y4DA05_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56043">
        <property type="protein sequence ID" value="OUO56043"/>
        <property type="gene ID" value="B5F75_07125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="28"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="128" mass="14766" checksum="E294E0F4BFD73497" modified="2017-08-30" version="1">MTKNNFNDLVQTFAVLRGPNGCPWDKKQTHETLIKCLRSETQELVDAIEKKDDENMKEELGDVLLQVLMHSQIAAEEGKFTIDDVIQGLYDKLHRRHPHVFGDHARAATPEEALALWKEMKKKEREGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA44</accession>
    <name>A0A1Y4DA44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">QacE family quaternary ammonium compound efflux SMR transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_05750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56124">
        <property type="protein sequence ID" value="OUO56124"/>
        <property type="gene ID" value="B5F75_05750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="111" mass="11594" checksum="614F60C34B3C1C39" modified="2017-08-30" version="1">MWKYYLFLAGAIACEIAGTSALKASRGFTVPAWAVLTAAAYAGSFWLLGLTLKGMSLGVAYAIWAGAGTVLTVLVGMAVFKERPDFAAVLGISLIVVGVAVMYLFSKTVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA69</accession>
    <name>A0A1Y4DA69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56113">
        <property type="protein sequence ID" value="OUO56113"/>
        <property type="gene ID" value="B5F75_05695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="67" mass="8034" checksum="48F2EC6B18D93630" modified="2017-08-30" version="1">MLLLDFWLPFVPKQALFVKSGRFSRKANFCKNRFFFAFQKEKILLILKIIQAYKIKNRRKFGGGFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAE7</accession>
    <name>A0A1Y4DAE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nif3-like dinuclear metal center hexameric protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56173">
        <property type="protein sequence ID" value="OUO56173"/>
        <property type="gene ID" value="B5F75_06025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="250" mass="27326" checksum="DCE8FB6A62FECBBA" modified="2017-08-30" version="1">MVNCEDVIRFLDTYLNSAQIPDASRNGLQVAGTPRVGKIVFGVSASLELFRKAKAAGADLIVVHHGLLWGQEQPITGLFRERIAFLLKNDLNLAGYHLPLDLHPVVGHNACLMRALRAERLKPFGEYHGVQIGFCGYVPPCSVEDVARTLQAYCGARAQVLAYGPKRIETVGVVSGGAYSMIPQAIAQKLDLYVTGALDEPAQEWCREGKLNCIALGHYNSEKPGVLALMELVAKRFDVQTEFIDVPNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAJ5</accession>
    <name>A0A1Y4DAJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LPS export ABC transporter periplasmic protein LptC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06410</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56247">
        <property type="protein sequence ID" value="OUO56247"/>
        <property type="gene ID" value="B5F75_06410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012260554" evidence="6">
        <location>
            <begin position="22"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="734" mass="84331" checksum="7B0B7A53BBBB3B4F" modified="2017-08-30" version="1">MKSASFFCLCAFLLSAAPVLAADNVLPKPDDPAFVFFTSDKATAEPDNKKVTLEGNVTVIQKTKDGKTRTVTGESITVDQLNTQISSVGPMTVQDSQGNVLKGNNVSVNYTTKDFTAEDISTEYPPLRVLSAKEISSITQKQTLKDATLTCCDIPDPHYTLSVGKLTVSPQKRVFGTNAVLRLDGFPVFYLPVFWRSLASQKPWTTYVDFTQSNKTGFGILTSTVFQPVLNLRPKLNLDYYTKSGFGFGGGLTAVTSPTLRGSGEFYFIHDLADNDDTRKLTDKNRWGVQGGYWWEMYDSSDHFNNPDGALYQFQTQFRMVSDPYFYDTFFRGNPYIFMPDQETNFSVSRQTRRSTLRVSYQQKDIYAWNKHEFMAEQRTLPEIKFMLLPFNDPLFKTANRLEVDFDNTSRIQYQNGRPNEEGPYQRQAHAKWTTEKSFRLSRAFTFTPSVFYDQTVTFADSQYKNGQDAWVARVGTDVNLQTHSFLGTTDFGYQFTKRLSTGTLSSDQLSPDKGIELNRLYLNNYYRPTFNTYVRFGTGFDLSDYAYSLKDGFGYEQGWKHLKSRIEPFLLEWGYKSPNGKFNFFVQDQYDLEEKNVSFIAQSHFFYKHHIIGLGFNNFADYTDPGSRYRTYSDQYTLTTTWGIRPTGAKWFMDLGIDAVLEPHSLVGFNKMFRFSYTLHDAQAEFTIRDRNDNLSFAFRINILCGGNKRIKGQIPEDTYWYPWRSQGDLRDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAX7</accession>
    <name>A0A1Y4DAX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">8-amino-7-oxononanoate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56357">
        <property type="protein sequence ID" value="OUO56357"/>
        <property type="gene ID" value="B5F75_05805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="48"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="396" mass="42891" checksum="A7A705E098FC341F" modified="2017-08-30" version="1">MSDIFEKCRNYKDAKLAMRMGIYGYFQPIESAQGPEVMLGGKKYIMAGSNNYLGLADDPEMKKAASEAALKYGTGCAGSRFLNGNTKAADELEARLARFKRKEAGLIFSTGYQMNLGVVSCLVKKGDYAIVDKLDHASILDGVKLSDGEMVRFKHNDPADLDRVLSKLPEESGKLIIVDGVFSMEGDICPLPEIVKIARKYGARIMVDDAHATGIIGKTGRGTCEYFGLENGEVDLVVGTCSKTFATVGGFVVGDADIIHYIRHNARSQIFSAALPPASVASITKALELIENDTSRRDNLFRLTAKLKKGLEDLGFDLGTSTTPILPVHVGSNENCFKMWRALHELGIFSNPVVSPAVPPGHALMRLTLMATHTDEHVAKIIDAFAQAGRSIGVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB26</accession>
    <name>A0A1Y4DB26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56246">
        <property type="protein sequence ID" value="OUO56246"/>
        <property type="gene ID" value="B5F75_06405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="323" mass="34527" checksum="C5FDAB6AB0A7543F" modified="2017-08-30" version="1">MIGVGVDIGGTFVKLFVMNEHGEIFRKEKIETDYSKGAKGFITQIGDYINAIQKEFQDQQVAVAVGAPGDVDNQKGVLRYNPNLKFKDIANWPLAQLLYKHTGIMPCVANDATLAAWGVYEADLKHQGTNILVVTLGTGVGGGLILNKELYQGSNGTAGEIGHTKIADTATGPLCGCGARGCLEAFVGTIGIKRRVLEAVTDYPDSILAQLVAAEKDFKIEIVSRAAEKGCKTALKVWEDTGHYLGIGLANFTLVLDIDTIVLTGGVSGAAPYFLPAVKRVLAAQQIQTPFKRLKILVSQNPNIGGVGAAMYAIYRAKKDTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB55</accession>
    <name>A0A1Y4DB55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_07135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56045">
        <property type="protein sequence ID" value="OUO56045"/>
        <property type="gene ID" value="B5F75_07135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="PTHR11626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="367" mass="41909" checksum="1384878C7FA12FF6" modified="2017-08-30" version="1">MTLIITFNNFIVILCVIARGSVNYFFKFAILIYMDTQTFLKNTSRSLYLSVQALPSAMRPTFGIAYLLCRYADTIADTPILPSSRRLYWVERFPHLIQTQDPQEIAQLTSEISGGSENPYEEALIEHLPQCLACLNRIPPHLQELIMDVVYAVCDGMQTDLSFFPHEKAPLPKAFDAPADLERYCRLMGGKPGLFWSRLICRTMPIAMPEEEFFELGQHIGDALQIVNILRDLPKDLRIGRCYFPSTDLQQAGLSAPDLLNPANSPRFEPVKRKWIAWGIANLKSAKAYFEQLPKTQPGLRAAVAWPILWTADTLFKVYQEPQLLNPKRRVKISRGVIYRTMAASPAFLLSNAVFAKWLDFKLRKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBA5</accession>
    <name>A0A1Y4DBA5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56454">
        <property type="protein sequence ID" value="OUO56454"/>
        <property type="gene ID" value="B5F75_04480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028351">
        <property type="entry name" value="CyaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001892">
        <property type="entry name" value="CyaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="482" mass="52581" checksum="5475383DF07DAF6E" modified="2017-08-30" version="1">MKHFGFFLTIFFLFAGGLVYGEEAVSVPSSDASSAAAQAAKDTAVPPASSSAVKESDTKPVHPAKNENPAMVLRDADGKPLPDINGKLTLEDCIRIALANSPQAVSAQLNLQNAHVNLNLAKSEFLPTVTAGASQDYTNSKMDGSSRTDHGSSDVYAQAQLSISGITDIARNVKTQQLALEQAELNVDSVKNDLIRTVKKNYYALISAVRAVAIRTQSRDLYQDQYERAAEYYRLGLRPKVDVTTAEVNLNNEELSLIRAKNLVKTASAELANSMGVTTPKTLEIEEILTFEKFEMPFDEAVQTAYANRPDVLSAHTNVRISQLKLNQAKAGFFPTFSFSAGFSKYGDDFSLDNEEARLMASVEIPIFNALKTYNGVKQAKISLENTLNTSRSLLNNVFLEVQSAYIKMQEAAESIPIAELNVEKAKENLDLARGRYNEGIGDIIELKDAEVAYTDAELSLLTARYDYASAVADLKQAMGTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBC0</accession>
    <name>A0A1Y4DBC0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56155">
        <property type="protein sequence ID" value="OUO56155"/>
        <property type="gene ID" value="B5F75_05930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12682">
        <property type="entry name" value="Flavodoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="52"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="206" mass="23111" checksum="38DE4017CE5340CB" modified="2017-08-30" version="1">MLKTILLLVLAAAVIGGGIGAVHLMRVAQRNKKEMAPFQGEKIAYTAQLGKALVIYYSRSGHTQDIAQRIQQRTGADLYRIELQEPLSSAPWMYLILKRQLSTGRYPPLQPPLPDVSQYDVVFVGSPIWWYTAATPVLQFLREMDFKNKKVVPFSTQGSNYGTFFEDFAARAKNAQLLKGESFNNLGPQYNDAVDNKITSWLNALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBE1</accession>
    <name>A0A1Y4DBE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56185">
        <property type="protein sequence ID" value="OUO56185"/>
        <property type="gene ID" value="B5F75_06095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="2">
        <location>
            <begin position="278"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="713"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1003" mass="112749" checksum="4F51024EC0762F16" modified="2017-08-30" version="1">MELFYAHYPSLEDAFVRRVQTRRSGVLSRWLVVCSSSLLAQRLRERLARELGAAANFYFLTAGALVSELDREAPGQPPALLPQDNLRDFLIKNLLAEPGLNRYPASRGFVQAVKSALRDLEDALAEPDVLDEHLRTAPDAVLEQDGARLEWFNRLYRRYLAAAAAVPGFRPYQQAFERALQQAENSDFLHGFDEIIFYGFYDMTGRQLELFNRLRALYAVTVFAPYLKHPAYRFAQKFFETNWLGAGSGENVDRGHFGALGKSGQFLFASSDSAPQAGVHIVSAADARGEVFYAAKEILRLTEKEGYRLSDIAVLARSLAPYQEEIQRVFAENCIAFNGSFSYPLSKFPLGVFCLNLFSLLANGFDRQTVLAVVSSPYFKPAQKNVWRRQAAQSLASRDLSQWRDLLPHGPEDDTSFLAWLEDTHARLDALARVRDWAGGAALALAFLEQNTDVSQLQGKETEIFQTVCEKIKSFSLYASIRPTVQPGEWVRELTDALTGLSFHETQAVRGGVTVTDVSRARGLQFKVVFLLGLNDKVFPLITPEDPVLRDYYRYVLRDVLGYWINQSLDRADEERLLFFAAATAGTEKLYTTYARAGQDGKEAVRSLYAAELARACGLDLAAQDAARVSGRLSERINQTESEFLTPKELSLSFILHPETAAAQYRRAGLWSGEKEHTLAAAAALRQSGALGAFDGVVQSGAEIFAKENAAGFSPSALQELGQCPLKYFLDKGLHLQEPDDPLSRQELSPDRRGTAYHEILKDFYEDLYQRGLTHEVSDAAALEYLERAFEKHCRADGYRLFGIYPVVWELILQEMKEKLSAFVLEDLHELGPYTPAWFEMPVSSEPSEELPLRLRGIIDRVDVDGVHKTFRVADYKSSRKGTKDLASDFFTHLIFQPFIYVWIARRLAAFEGYESDGSCLLSINKGYVRRDLSADAYRRMQPRACGFLKQLAEMIQTGTFFISPSDLCAYCPYAGICRRDSFKSLLRARKSAASQALEEARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBF1</accession>
    <name>A0A1Y4DBF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Quinolinate synthase</fullName>
            <ecNumber evidence="3">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_04595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56477">
        <property type="protein sequence ID" value="OUO56477"/>
        <property type="gene ID" value="B5F75_04595"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00550">
        <property type="entry name" value="nadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="38228" checksum="E88991D5E6662AC2" modified="2017-08-30" version="1">MLQTLDKEARLTEEAHRLYGLLKSVSKDKNAKWTYEDCLAAAPYTLSINRFKKEQNAVILAHSYTTPDLVYGVADFRGDSYELALKARETKADVIVFAGVWFMAETAKILNPEKKVLIPAGRAGCTLADAITGEEVKKLRAQHPGVPALCYINSLAEVKAQCDACVTSGNVFDIAQKMPGNELIFVPDLLMAQNLEAELVRRGTPKKIIAAGGSCYVHGHYRPEDVQKLRAEHAGIKVVAHPECPIEVCRLCDYMGSTKGMSAYVAASADKCFGMLTEFGLVNRLEAEHPDKTFIWPCGICEYMKRNTLANTLEALIDPRPEQVVEMEPALAAAAKKSIDKMFELAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBF8</accession>
    <name>A0A1Y4DBF8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56487">
        <property type="protein sequence ID" value="OUO56487"/>
        <property type="gene ID" value="B5F75_04650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012079405" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="192" mass="21193" checksum="218B0CA180314C18" modified="2017-08-30" version="1">MKKAAALIALFIGGAFVVTAAQTAYKPQTIRQSPQYLSTDPALVEDTCPGHDILNRFTCSKKQSPGYSCFDVYMVQGDPIDAERYTLLDQSITLENSSAQPSCTFENELTCENFLQALNYNLDFSWFISNFPSSSFPQCGETYSCTRIACMRPLPPAADGSPRSQKLSCVFKKNQIFFLGAEISCQDKNAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBF9</accession>
    <name>A0A1Y4DBF9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56494">
        <property type="protein sequence ID" value="OUO56494"/>
        <property type="gene ID" value="B5F75_04685"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="165" mass="18810" checksum="7CA73ED1C6805BDB" modified="2017-08-30" version="1">MPKAVLALGSNIPPAKENIDRAIEALSALGTVKEVAPYIVSKPEGFAEQPDFINTVLILSTPYQPLPLLKKLKALETRLGRTPTFKNGPRVIDLDILFYDDQVLFEDDDEYPLFIPHPRLQEREFVLKPLSYILSDFVHPKLGKPVYRLYRELMKKKGKPDCHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBG8</accession>
    <name>A0A1Y4DBG8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NfeD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56497">
        <property type="protein sequence ID" value="OUO56497"/>
        <property type="gene ID" value="B5F75_04700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002810">
        <property type="entry name" value="NfeD-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01957">
        <property type="entry name" value="NfeD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="NfeD" evidence="3">
        <location>
            <begin position="51"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="141" mass="14919" checksum="B4F5FFA3EBE516C0" modified="2017-08-30" version="1">MNYYVWLILAVGCFVGELFTMEFSLACLGLGLAGAALAAWLGAGLWLQAGVFAGVAAAAWLGIRPLAKRHFYRNAPRVKTPAEEVIGKTAVTETEVGPLLNNGRVKVAGESWKATALQTLSAGTECVVEKLDGVTLTVRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBK2</accession>
    <name>A0A1Y4DBK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56544">
        <property type="protein sequence ID" value="OUO56544"/>
        <property type="gene ID" value="B5F75_04950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="112" mass="12758" checksum="D9BC3D026597A8BC" modified="2017-08-30" version="1">MKCTLKRTGEVLAKEVEIANTYFTRLKGLMFRRGLEPGKGLLLDPCPQIHTCFMRFNIDAVFFNKDGLVLYVAEQMKPWRFGRFVRGSRYTLELPGGTLAGRVKKGDEVLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL8</accession>
    <name>A0A1Y4DBL8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56554">
        <property type="protein sequence ID" value="OUO56554"/>
        <property type="gene ID" value="B5F75_05000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="230" mass="25832" checksum="289359958B7494E8" modified="2017-08-30" version="1">MINKFEKQLEKWNGGVLRGAQAKLARYLHVSTATVALWATGKRRPSKGYAAQMAQLFGLDSYDVMRLFPATTTYPDLASERATQSLRDAQAPENTYSADNLHLKTPPAAARSNSVSLPVLMGVPENYPLYKEEDVAEWWTLPLRYAKGAKYLVQLGHEVPHHLYFIRPETNLIEGKWMLFKTPKGYTVKKGFQKEGSICLCSAERKEEETYSPGQITPLGCVVCKVTDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP5</accession>
    <name>A0A1Y4DBP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transglut_core2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0162 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56496">
        <property type="protein sequence ID" value="OUO56496"/>
        <property type="gene ID" value="B5F75_04695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032698">
        <property type="entry name" value="SirB1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13369">
        <property type="entry name" value="Transglut_core2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transglut_core2" evidence="2">
        <location>
            <begin position="105"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="281" mass="31713" checksum="64BA683C0FF101AA" modified="2017-08-30" version="1">MQILGHDGLKALIKLLETESDAYGPVLKSALADAIKANPAQVQQVMEEEFKTSAPRAVLNTLEEICWEDLSAALARFSAKINPDLEEGLALLSKFTSPTTARGDVSAPLDKMAASLRPVLLNAKNYTEIAVVLGHYIFQTEGFTPLQTNTDIKDISFARFLRKKRGSSLCVACLYACLGQRYGMDVSLVDLAGRVLVHVRDFAHLQSLFVDPLDNGKILTEADCRRYIRSRQIAWNDDFFTPLSSRQIIRRFIANMIYILNKLRDERRLKYLRNYLEIIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBV8</accession>
    <name>A0A1Y4DBV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="8" type="ORF">B5F75_06895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56335">
        <property type="protein sequence ID" value="OUO56335"/>
        <property type="gene ID" value="B5F75_06895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="13533" checksum="DE176988C2A2D783" modified="2017-08-30" version="1">MATKQERYQYRKDRSRGHLLKNGAHRPRLSVYRSLKYIYAQIIDDNTHSTLVSATTLSKEFEGKFDTSAKSIEAAKALGAAIAKKALEKGISEVMFDRGGRVYHGRIKALADSAREAGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW6</accession>
    <name>A0A1Y4DBW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56556">
        <property type="protein sequence ID" value="OUO56556"/>
        <property type="gene ID" value="B5F75_05015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="119"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="206"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="291"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="397" mass="44528" checksum="64FFEF1DE0C5B038" modified="2017-08-30" version="1">MTTNEEIKNTEDTINEQEMTMDQLIAQQESLSEKLYKKEIVEVPVVQINQDYILVDTGAKKEGAIAVSEFAGKTLPAVGDTISAVLVKRGSDERPAILSHKKALEALGWDVCKKAYEAKERVKGTIVQCVKGGYIVEVFGVNGFMPLSLSELHTAYKHYLPVGAKIKAQIVEFAKEKQKLIISRKQVLEEDEAVRREQVLGEIKEGDVLRVVVSKVDKDKLFLRFHGIEGIVNLENIAWKDPETAIANYRRGQRLKAKLLALDKETPRLEFGLKQLFLNPADALKRRYPYKSSVKATVTKVDPENGVECTIGKNNTKGFINPFEMGRDFTAKEGDTITALVVGVDPETFTVNLSVKKYDQVQNRKVVAQYLKQAPRPTLGQLLQDSFKTENDEEESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY6</accession>
    <name>A0A1Y4DBY6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56664">
        <property type="protein sequence ID" value="OUO56664"/>
        <property type="gene ID" value="B5F75_05590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="117" mass="12594" checksum="190A1F7EA15F31AF" modified="2017-08-30" version="1">MAKKKRKCNACALFAGTDSLAPCRFGAGHSCVVAAENTACKMFVPLQQPKSKEQAVAPTMEAGDGVDEPAPGSAPFCNEFAKCNNAEGCDTCREFTLWLAEREKRFAAQNSQKRSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCH5</accession>
    <name>A0A1Y4DCH5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56292">
        <property type="protein sequence ID" value="OUO56292"/>
        <property type="gene ID" value="B5F75_06665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012443">
        <property type="entry name" value="DUF1646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07854">
        <property type="entry name" value="DUF1646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="353" mass="37724" checksum="A9273D95B6F0D61A" modified="2017-08-30" version="1">MELSVLQTVLLALLIVVVLFLPLTVHKVEENLEAFLFLCGAFAVTVSKSWSGQLVLTALEDPIKITIAVLVAGLLFRKFNKSLQKLTQKAVKGLGLRCTLFGIVFVLGLTSSLITAIIAALVLSEVAVMLPLERKGRVKLVVYACFSIGMGAVLTSIGEPLGTVVLSKLSGAPHYADFFFLIDHLGWFVLGGILFMAGLASAIRDNPIQKAPGPKPAETAQDEHSVKSIVIRAAKVYLFVMALVFLGDGLKPLAMQTISHLSAGWLYWINTLSAVLDNATLAAIEVTPDISTRTLTFLLMSLIISGGMLIPGNIPNIICASKLGIKSKEWAKAAVALGALVMLVFFVILNAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCJ8</accession>
    <name>A0A1Y4DCJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56827">
        <property type="protein sequence ID" value="OUO56827"/>
        <property type="gene ID" value="B5F75_02995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="472" mass="53753" checksum="FCA853707DA69E98" modified="2017-08-30" version="1">MVCFTRNARRFLPGTLVFLLLFAFGCNYHGRIKRGIYKTPPFDDKIEASVMVPADRFLQQAFTFKDDNLTPINSYTFRIDDGAAVAAADALGTLFSQADVNEYRFRRQYDYIAELDYKVTEENEVYSSLEAEDGFLWARKYRIPKFHTFTVLTLRDPHTRMPLIKLDADRVSYLEFSNTAIGAYWFNKLTFSVLFPLIAPVYTSSAGGSIRQTLEDDLRACLQQMMKELEENRIVFQPGISPALARNDRRYRPFMEKTTYVETPQGHGTGFFISPDGYMITNAHVVSGNRDVRYYLYEDLPFEPRRAEPPFRYARVIKVNDSRDLALLKAEGTFPYFKLDADRSHYQTGDSVFAVGNPMEEFWSVSEGIISAVKDENGVDVIQSDVSTNRGNSGGPLVHKKSGNVIGVTSYGYKNSEAAGLNFSISAFEVKRTLGIDQPIDEKKLLREEILDRPQTPQKANVLYQDGQNYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK0</accession>
    <name>A0A1Y4DCK0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56605">
        <property type="protein sequence ID" value="OUO56605"/>
        <property type="gene ID" value="B5F75_05280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="330" mass="37953" checksum="1823DFBA238F00DE" modified="2017-08-30" version="1">MTDFKFPLISVLVPVYNAEPFLVMCLDSIFAQTYPNFEVVCIDDASADKSADILEQYARKHPRMKLLKLPAHQSVAVVRNLLLQEAAGEYIAFIDADDSVHPEYLAHLYQAAQNTGADVVRCLYQLQDIRKNTLVPCEKKYKEFSHLLPPSTSLERLQAALDDSQVWLKLIKTSLLKEHKIGFIPHVLPEDISFEILLYQYSKKIVFLPEHLYVYRVGNANSVSSNRSLCAYGTLEAMVFLCGDLVQRHLVEKAFYEKIIGLTLHAVRRIRKYSFAPEYAVSKICREAFNQIEKFARYCGPVKKYKYQFMCQIARHLKDSHLSYLACIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM0</accession>
    <name>A0A1Y4DCM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56853">
        <property type="protein sequence ID" value="OUO56853"/>
        <property type="gene ID" value="B5F75_03130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00910">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="85" mass="9630" checksum="66564BD951F85D8E" modified="2017-08-30" version="1">MKIFGMVFVLALFLFGVAVMRIEINRSGRTISQLQNEVEIKEARNQYLQLEISRMSGPGSITRLAEEKLGMVPAKPHEIVVLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCT8</accession>
    <name>A0A1Y4DCT8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56836">
        <property type="protein sequence ID" value="OUO56836"/>
        <property type="gene ID" value="B5F75_03040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="168" mass="18289" checksum="E5AE5ABE39EE91B9" modified="2017-08-30" version="1">MCGWLGILLVVVIAAGIWYFFPRRQALYAGVNPPIIEFLTTELKRFPLHQAVFQNDVAAVQQLLKEGHSIEEETDDGQTVLHIAAECGLEEMCRFVIKQGVKVDSLDNFGGTALHAAAACQNGVGVIRVLIENGADAHLKDAAGMTPGALAEKYKHFKIAAYLKLRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCW9</accession>
    <name>A0A1Y4DCW9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recO</name>
        <name evidence="9" type="ORF">B5F75_03195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56866">
        <property type="protein sequence ID" value="OUO56866"/>
        <property type="gene ID" value="B5F75_03195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="27026" checksum="6871F0995010F27F" modified="2017-08-30" version="1">MIFTDSGIILLRQDFREADRMVSLYTREHGRIHVRLPGVARAAGKLKALSEPFVYADYRIYVRRGGVVGTVTGGKLHQVFPTIRKDLKRTALAFHFCELFQRLTPLHQPSEEKFELLLASLTELEYGEPNPAFAAAFTLRLMMLAGFGLDHPVLQISPEFWRRMHEDKLSSLVFTDAEDLLSLAKCNSVCRRFLNRYLSYPLHTLKSFGLEDTEDLHQEHEMPLPDWAPLETASAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCZ9</accession>
    <name>A0A1Y4DCZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56492">
        <property type="protein sequence ID" value="OUO56492"/>
        <property type="gene ID" value="B5F75_04675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="265" mass="29285" checksum="DF399A7846F4C876" modified="2017-08-30" version="1">MANPLLMGIVNATPDSFYDGDPQNNLASLLAKCKDYVQSGADILDIGGESTRPNATPVSAEEEISRVLPLIRAVRQKWPQLPVSLDTVKIPVAQEGLKAGVSIINDVSGTPDKEMFRLVRDFKAQIVVMHTRGTPQTMQGLTEYAHLLEEIKDFLAGKIQEALSCGLAKENVIIDVGFGFAKTREQNYELLKHLSFFKDLGVRMLVGVSRKTFLSQKRELPPKRKAQTLAAQLVALQGGADILRVHDVKDTRKIMNFYQELEAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD26</accession>
    <name>A0A1Y4DD26_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">D-glycero-beta-D-manno-heptose-7-phosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56926">
        <property type="protein sequence ID" value="OUO56926"/>
        <property type="gene ID" value="B5F75_03525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01172">
        <property type="entry name" value="RfaE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011913">
        <property type="entry name" value="RfaE_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02198">
        <property type="entry name" value="rfaE_dom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="20"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="329" mass="35560" checksum="F9836A0DE9A7FA54" modified="2017-08-30" version="1">MHTIPTKRLKEILKDFEGQEIIVVGDIMLDHFIKGTVSRISPEAPVPVVDVKKEFFVAGGAGNVAVNLAALGARPVMISVVGQDLGGEMLKGFLREKNVNIYGVAEDPDRPTTQKIRVMAEQQQIVRFDRESKKTISPSVSSLCMKSFELAVKTAKGVILSDYGKGMLSDHNIQTIIETCRKHKIPVCVDPKIDNFKKYKNITCMTPNTKEAWEGMGEAPKPGEEAIETLGNKILKMLNADSILITRGADGMSLFEKGKTKPVTVRATAREVYDVTGAGDTVISVLTLALSTGATLQESAVLSNYAAGIVVEKSGTATATREEIEGVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD43</accession>
    <name>A0A1Y4DD43_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">B5F75_03625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56946">
        <property type="protein sequence ID" value="OUO56946"/>
        <property type="gene ID" value="B5F75_03625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="198"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="41"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="154"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="34427" checksum="24D8B461FCC1768D" modified="2017-08-30" version="1">MDDKNFKSGFAVLAGLPNAGKSTLLNNLAGGLLSAVTNKPQTTRQNILAIAEGDHYQVVFVDTPGFLTAQYKLQQTMVSCVDRAVREDADLVIFLVDATADYALNAKLVEKLKTVYCPIFLAINKIDLIKDPSVLDELEKRVKADLKIAKTFRISAAQGTQTAELQQAVIEAMPFSPAYFPPGQWTDRWERFYVAEFIREQIFLLYHKEVPYSTYVEIEKFTEDLGPKNYIRANIHVERESQKPIIIGKGGSAIAELRKRAQKRIEQFLGRKYRLELNVVVSPNWRNDTQMLEDFGYIVRDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD81</accession>
    <name>A0A1Y4DD81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56825">
        <property type="protein sequence ID" value="OUO56825"/>
        <property type="gene ID" value="B5F75_02985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="84" mass="9328" checksum="92231E4A37DD19D6" modified="2017-08-30" version="1">MTPLQENIQTAVSRMTEYLTEHKTASSWQLKIMFRLSSSVLYLALGVLYSQGKISLEADGINYNVTWGQKPAPVPPATPIAENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDB7</accession>
    <name>A0A1Y4DDB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57026">
        <property type="protein sequence ID" value="OUO57026"/>
        <property type="gene ID" value="B5F75_04050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="127" mass="13243" checksum="7DCBE0E7D31CD1A3" modified="2017-08-30" version="1">MLLDQNAMMSDKQAVAATAASENILDLGAASNAVPGALFAVCRTDEAFSGVTQVKVSLQTDDTADFSAAQELMAVTFALADLQSVKNLFAVVLPNGAKRFLRAYYTVSGSGTAGKLSCFLTDGVDMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDD0</accession>
    <name>A0A1Y4DDD0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56875">
        <property type="protein sequence ID" value="OUO56875"/>
        <property type="gene ID" value="B5F75_03245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="398" mass="44579" checksum="B53C513D376A04F3" modified="2017-08-30" version="1">MKSAKNKVLKPRFGGVFYRAFKRFCSTRAFGKGPDKRAFLKYNENMKTSRFLIALLVCFGFVACTPPEDEVHPKRRSARADNLQRYMNKAQHHRAMAQARSKAIVQGPLVDADVLKEFLPQMPDLRISSQIFAQKNALQNEVRQAHARRAAQETGELLAQFREEAMAAALTAQTPQELATKLDETTALYSQKIAAFSKNQQAASWALPDEEQSLLSRQTLQDAVDGLTEGIERDYGSVCAQKAQPVLHKAADDYWLALSSVSDPQEMEQELTRVGDEADEAFRGVVAAYGDPVVTVSDDQAASLRARLIAAHQQIENQFDKLYGKEAVLKTRDIFERYKDAADQIVRRAARLSQMQNELNQAGETYRKEMAALQVALNESLERRAAEVRGIPVSVARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDF7</accession>
    <name>A0A1Y4DDF7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05005</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56682">
        <property type="protein sequence ID" value="OUO56682"/>
        <property type="gene ID" value="B5F75_05005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="13"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="329"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="362"/>
            <end position="369"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="571" mass="63549" checksum="92E3E7D89CEA019C" modified="2017-08-30" version="1">MWPFVKPYWFRALLGLALALPVGALDATVAMFMKYYTDDVLVAKDAAFAAFIPLLIIVFVLVQSVLTYVVKYLNSWVGNKITLDVRKKLFRKLLSMHSGYFDTTDSGYIMMRYNGDADTACNGLINNLRMIVTRVFSTITLIFVLFYNSWQLTLIAVGAFSAAGALIFIVRRKLEELVRNTVVINSIAMRAYNEMFNGNRTVAAYNLQDDQEKRFDRLMDDVFSLNMGMVKHTGWLSPVMHFIVSLGLALVFWQSSSMIVNGTITSGNFTSFVAALLMLYTPVKTMGDNYVDIKKAFLAIDRIFEIFALKTEISDKPGAVTLTGLRQDIRFNHVSFAYKPGTYVLKDINLTVPVGKTIALVGNSGGGKSTIVNLIPRFYSVSKGSITIDGVNIEDFTLKSLRDHIAVVFQDNFLFTGTIRDNILIGRPGATEKDLQEAVKNAHLDDFLRTLKNGLDTELGERGLTLSGGQRQRVAIARAFIRQAPIVILDEATSALDNKSEAIVQKALDNLMKNRTVFVIAHRLSTVINADKIVVLNEGQIVEEGTHEELLAIPNGAYASLYNAQFKKKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDN3</accession>
    <name>A0A1Y4DDN3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57207">
        <property type="protein sequence ID" value="OUO57207"/>
        <property type="gene ID" value="B5F75_00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042085">
        <property type="entry name" value="Ap_crown"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012689326" evidence="2">
        <location>
            <begin position="23"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="459" mass="50804" checksum="DC70DB168030CC0C" modified="2017-08-30" version="1">MKNFRRLAAVLAACFFLTGALAAGEVKNVIWIIGDGMGPEAMGLFMQGVRYAGLEEYAGRVSNLEKMMNSGEWGLFFNNTHDTVVTDSAASATQMATGRFSRPEFIGIDYNSQPAETFLELARKQGKSIGIITDTYVADATPAGFTAHAQNRNQKMKIARQLIAFAPEVVMGGGLKYFTTGENKKLLRQAKKKGYRVAKNKKELAAVKSGNVLGLFAEESLPMSLEMDEYPAIPSLTEQTQKAVELLSKNENGFVLVVEAGKIDWAGHANDAGAWFHEMKALDELLGYVNAYADKNGETLVYLNADHDTGLGTFTYRHLGKDKAMKKTAQGEVLYGGDVDYASFETFRQFDKQKKSLYNLEMELKKMPAEKLTPQYLQKRLSEAMGFEVDMTQFENLSDVSGLFKQLNESRGIVWASVNHSSLPILSVAYGPDADEFTGVYHNTDILPRMKNVLGWSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU6</accession>
    <name>A0A1Y4DDU6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate formimidoyltransferase</fullName>
            <ecNumber evidence="2">2.1.2.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04145</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.5" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57045">
        <property type="protein sequence ID" value="OUO57045"/>
        <property type="gene ID" value="B5F75_04145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005542">
        <property type="term" value="F:folic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030409">
        <property type="term" value="F:glutamate formimidoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013802">
        <property type="entry name" value="Formiminotransferase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037070">
        <property type="entry name" value="Formiminotransferase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004227">
        <property type="entry name" value="Formiminotransferase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012886">
        <property type="entry name" value="Formiminotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037064">
        <property type="entry name" value="Formiminotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022384">
        <property type="entry name" value="FormiminoTrfase_cat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02971">
        <property type="entry name" value="FTCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07837">
        <property type="entry name" value="FTCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01221">
        <property type="entry name" value="FTCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01222">
        <property type="entry name" value="FTCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55116">
        <property type="entry name" value="SSF55116"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02024">
        <property type="entry name" value="FtcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0290">Folate-binding</keyword>
    <keyword evidence="5" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTCD_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FTCD" evidence="7">
        <location>
            <begin position="182"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="326" mass="35532" checksum="1D1EAEB29891E519" modified="2017-08-30" version="1">MKIMEAVPNISEGKDPKIIAACAQAARQACAQAKLLHTDSNPDANRTVLTLAGTPEGVRRAAFALMQTATRLIDMRLQHGAHPRLGAVDVCPFVPVAGMTLAEATEQARLLGQEAAEQLGIPVYFYEANARQENRKNLAFIRRGEYESLPQKLAELPPDLGPREFSPHVAKTGAVVIGARNFLLAFNVSLNTQDTAAAKEIAGVLREKNGGLPAVKAIGWLMPGYQAAQVSFNLTDFHKTGLAQVFEACRREAEARGLSVTGSELIGLAPQEALAAAGRFYLPDCQDTHTLLRQAVLRLGLNKIRPFHLRERILEFRLQEELQQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU7</accession>
    <name>A0A1Y4DDU7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribose 5-phosphate isomerase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57294">
        <property type="protein sequence ID" value="OUO57294"/>
        <property type="gene ID" value="B5F75_00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="150" mass="15991" checksum="B4D00F455D6AE7B9" modified="2017-08-30" version="1">MKIAIGCDHAGFPLKETVKETVTRLGHEVIDCGTFSTERADYPDYADKVAKLVASGQADRGILLCGSGVGVCVTANKTKGVRACVCHDAYSAKQAVEHDALNVLCLGARIIGPALAEELTQRFLSASFLTGSRHEGRLNKVKAIENANFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDZ9</accession>
    <name>A0A1Y4DDZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57343">
        <property type="protein sequence ID" value="OUO57343"/>
        <property type="gene ID" value="B5F75_00795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="20841" checksum="66DC4B35B9EBB1A3" modified="2017-08-30" version="1">MKTRFVITLLLAVFVCACSTTDFRSRKKVTQGIDYSRYPGNEVYYEFTSDIPTDPSVLAGADENAQPGQPLSEDEDFTSENIASTYGNYGDVVVNVAAHKFKLGPSASRKEMAVFQKALDQAYTVALKKYRPVGFTYAMSSVGAVNPLSDIEVRCMLSERSANDVGQSTCTLFFNTIASNYIEQMKEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE56</accession>
    <name>A0A1Y4DE56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57326">
        <property type="protein sequence ID" value="OUO57326"/>
        <property type="gene ID" value="B5F75_00685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="157" mass="17407" checksum="1E65F96E22FDAA55" modified="2017-08-30" version="1">MKTAEIASHSREETLALAGRFARALKGGEIVFLRGPIGAGKTVFVKGVAAALGLKSSPTSASFSLMKEYKNKHCRLFHIDLFRLEEGEVFNLGFEEMLEDDKAIILAEWPDPIRHMLPEDRLEMDFILQEGDDRVIALKSFGRVSDALLEALCKAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE80</accession>
    <name>A0A1Y4DE80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56962">
        <property type="protein sequence ID" value="OUO56962"/>
        <property type="gene ID" value="B5F75_03705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="101" mass="11419" checksum="FC32AF8A2BEF1CBF" modified="2017-08-30" version="1">MASGKMPDSLDELDVTPPQTSLLQIIVVGKDHVRFQMPSKLKGLYYMWYPYFVGTSLQSKHFCNVESGDASVREEAKKICRAVSGREPDNCGTYGCRYPMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE82</accession>
    <name>A0A1Y4DE82_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">crcB</name>
        <name evidence="10" type="ORF">B5F75_01285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57434">
        <property type="protein sequence ID" value="OUO57434"/>
        <property type="gene ID" value="B5F75_01285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="120" mass="13044" checksum="02F2336B0A6CC263" modified="2017-08-30" version="1">MMNFVYVGLGGFIGAALRYGVSMGAAAFAWRGHWATLAVNVLGSLAIGYLAPYFENPSHPARLFIVVGLLGGFTTFSSFSLDTLSLYHNREFFLAACNVLLNVLVCLAAVWAGFRLHHAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA8</accession>
    <name>A0A1Y4DEA8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57386">
        <property type="protein sequence ID" value="OUO57386"/>
        <property type="gene ID" value="B5F75_01025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186896" description="Glyco_hydro_3 domain-containing protein" evidence="4">
        <location>
            <begin position="19"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3" evidence="5">
        <location>
            <begin position="28"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="543"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="565" mass="61612" checksum="72210DA9C9EFADDB" modified="2017-08-30" version="1">MKHWLSVLLLCAALPLAAATRFEDLSYEEKLGQTLVVFVDIDSASLVRPAIEQGKVGGVLIQWGNYSLKQTQELIEKLQSWAAKSPHQIPLLIAIDYEGGTVYTPITLGFDYLPTNMMLSASQDEEGAAAIAYLAGLELRRAGIHINFSPVLDVNSNPNNPIIGVRSFGSDPQNVTKMGISLMNGFKAAGIISVVKHFPGHGDTSADSHYKVPVVKAGYEELQKIHLAPFAEAVRQGVPGVMTGHILYPALDSKNIATFSKPILHDLLREKLGFKGFVVTDSLDMKSATSFCTIAGCAVRALDSGADMILLGRYIKPLTVFKQILTETRQKNMQPRVEDAARRMFALKEELGLLDGTAEIPAPIEQAYKAELEKISDESVTLVRDRNGMIPFTVPEGKKPTVCAVFFAPSRFADQLMGFSKPFLEKGWNVRSYNAALTPRKKDSQRAAACAKGADLLILTSLQWADKTNINQKNAIHGLIEENKNVVFISTMSPYDIKNYPEADVILATYGLNKYALQTAANIILGNLAPQGVLPVDLQLPPETTSSAADVRSKTRTPQAATKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF1</accession>
    <name>A0A1Y4DEF1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57524">
        <property type="protein sequence ID" value="OUO57524"/>
        <property type="gene ID" value="B5F75_01760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="332"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="551" mass="60108" checksum="19DD592ADB96ED3A" modified="2017-08-30" version="1">MLVRLHVQNFAIISDLTLDFAPGLNVFSGETGAGKSIVIEALGFVLGARGDVSAIKDGADKMTASAVFSSTDLPAALRKEHQIAADVFTLKRELDRKGKSKAFIEGRPATVSALAQLGKALVDFHGQHDHQSLLHASVHLMLLDQFAGHGALVQKTQDAYRQMQNAAAKLDAARMSSQERERLLDMSQYQLKEIEDVNPTADEDLQLEQNLPKMKHAGRLLELAQNAYEELYAAEDSATSRAGKALREVQNMAELDDHLNALAQDLNSALLTLEDAASTLGSYKDDINLDPQTLDRMLARHEKIKRLKAKYGPEITDVLETARTLREKIDLLQHGEEHEQELLKELEQARQNLLALAGELHDKRMRAAQRLAARISEEIRPLGFNAIRFSVAVEMDEENLGPTGADKVEFLFSPNPGQALRPLKNIASGGEISRVMLGLKTVLAPTVPVMVFDEVDAGIGGETGHLVGQKLHQAAHGRQVLCVTHLAQVAAQADQNFYVSKKASKNATDVSIQPLSGEKLTAEIARMLGGGDKHSAAFSHAKELLADAKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG7</accession>
    <name>A0A1Y4DEG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57477">
        <property type="protein sequence ID" value="OUO57477"/>
        <property type="gene ID" value="B5F75_01520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="1">
        <location>
            <begin position="18"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="614" mass="70633" checksum="C645CEB6585CE8AF" modified="2017-08-30" version="1">MIISPHSLDTDLGQLLAEVATAKIQLPEFQRSWTWDDNRIKGIIASLSQGYPMGAIMRLQYGNPEIKFKYRTITGVKEQNVEPEYLILDGQQRLTSIFQAMYSTEPVKTKTDKNKEIQRYYYFSMEGCLNEEIDRFDAVISVPKDRKIKENFDRDVKLDLSTRDLEYQHKMFPVNIIFDSSRWMDWIFKYRDFYKDDKAACDLLEKFQNAVVNTIKSYKLPVITLDKSTPREAVCKVFENVNTGGVPLTVFELVTATFATYTNPETKEGFDLRKDWKECRDSIQDIGAPLRTDILDDIDETSFLTAVTLYTSYKDKQEGKVGTVSCKKKDVLALNFDSYCKNRAQVVEGFKLAKEFLLKYQYVFRRKDLPYTTQIIPLAAICAFLGRSKCNEPNIVNILTRWYWCGILGEMYGGANETRYANDIEDVIEEVNGRPNPARTINAAFFSATRLLTLQTRLSAAYKGIMALIYKEQCHDFINNTTMDIVHSLSEAPDIHHIFPEDYCKKQGIDKMRYNSIVNKTPILLATNRSIGGDAPSVYIDRILKKVNGLTEEMLKSRIESHLINYTALKNNDFNTYFIDRAKKILIIIEKAMGKTVSDKNSENTIKQFGVSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF25</accession>
    <name>A0A1Y4DF25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57525">
        <property type="protein sequence ID" value="OUO57525"/>
        <property type="gene ID" value="B5F75_01765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="101" mass="11547" checksum="953E6C90E6828A14" modified="2017-08-30" version="1">MPNGFKKITPFLPHHWLELKGLSRLYLFLFYATLAVGLYAGVCWLETYFQTPQQLALNSAPLRRLYGLAALQAGLACLVWLFLHRFCRTLQRLSSLSETGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF27</accession>
    <name>A0A1Y4DF27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57242">
        <property type="protein sequence ID" value="OUO57242"/>
        <property type="gene ID" value="B5F75_00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025833">
        <property type="entry name" value="GDYXXLXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14345">
        <property type="entry name" value="GDYXXLXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="16488" checksum="3AE4B0DA8D004A70" modified="2017-08-30" version="1">MRGKIFLAAAGVLAVLLGGYAWRTQTARQQAPAVYFKMAPVDPRAMLSGDYMELFYDLERSPENWKNGQAVVFYAAENGVVQTAPTEREVKVFPFEKRLRLPHQFYFQEGTGTKYEGAAYAKMRQLPGGRFLIEALTDEKFNEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF30</accession>
    <name>A0A1Y4DF30_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">B5F75_00790</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57707">
        <property type="protein sequence ID" value="OUO57707"/>
        <property type="gene ID" value="B5F75_00790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1e" evidence="12">
        <location>
            <begin position="14"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="277"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="465" mass="53115" checksum="D1FE0D11F3E21D5E" modified="2017-08-30" version="1">MYLYNTATRHKDEFKPQNEKQVTMYCCGPTVYNYAHIGNLRTYIFEDLLARTIRLHYPLKHVMNVTDVGHLVSDADDGEDKMEVATAREGKSAWDIAKFYEAKFWQDYDALHCSRPSVISRATEHIKEMIALVKTLEEKGYTYRTSDGIYYDTSKFPRYDALVGHARISGLQGGARVEMSDEKRNPTDFALWKFSPKDKKRQMEWDSPWGVGFPGWHIECSAMAMKYLGHTLDIHCGGIDHVTIHHTNEIAQSEAATGEKYVNYWVHGEFLILRSGKMSKSGGTFVTLDVLREKGYEPLAYRYLCLGAHYRTQLEFSYESMDSAAKSLKNLRALCSQVRTAAQNRAQQTDKSRAWKEKFTAAMEDDLNAPKALALAWEAVRNAELTPGEKLDFLQFADTILALDLFVQPEVSSEPLPEEVTRLLEERARARAAKDWKKSDELRDAIAQKGYVVKDTPKGQQTEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF39</accession>
    <name>A0A1Y4DF39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57545">
        <property type="protein sequence ID" value="OUO57545"/>
        <property type="gene ID" value="B5F75_01870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="115" mass="12349" checksum="69943A444972B8B7" modified="2017-08-30" version="1">MNKIFGYLLICAGLLLIFFSLVGMYKVFVNGNAVVPVMQLADLQLNTTYGPVQIPMKSIGTLVNLGLFAVFMVFVLSAGGTIAGIGNGLLKTERIYEALLENPSAPAQPEARKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF42</accession>
    <name>A0A1Y4DF42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="8">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nadD</name>
        <name evidence="11" type="ORF">B5F75_00330</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 8">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57262">
        <property type="protein sequence ID" value="OUO57262"/>
        <property type="gene ID" value="B5F75_00330"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005249">
        <property type="entry name" value="YqeK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00488">
        <property type="entry name" value="TIGR00488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="9">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="203"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="376" mass="42734" checksum="481E65BEABDACA69" modified="2017-08-30" version="1">MKVLVFGGSFDPVHKGHVSLFRRAMKTIAPDVAHIVPAYHSPFKAKSPTPFRLRMKMLKQAFAGFSGNIVFDDYELKQGGKTYTYQLVQYLKKRYKNPEIYLLVGTDCLNDLHNWKNPRYIFENATVVAGKRRGYDENPAAFKHIFLPGFFPKLSSSRVRAHILACGDVPDTIPPQIAPTIRENKLYGLTVHDWLRAHLKTNRYLHSKNVAEMAAALSDIYDVNVESAVKAGIMHDAGKGFSGPELIRFCKEHKIKVPFFEDICRLEPSLLHSYASAWIAKHLFGVHDKDILNAITEHTLGSLHMSTLSKILFVADISSKDRKYKDAFLIRNLALQDLDAALLYAANRKLLFTIDSQKWLCPVGIDLWNHLIKQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF49</accession>
    <name>A0A1Y4DF49_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57272">
        <property type="protein sequence ID" value="OUO57272"/>
        <property type="gene ID" value="B5F75_00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="18608" checksum="729AB685DD37363C" modified="2017-08-30" version="1">MKRGFTLIELLAVVLIMGILTAIALPQYRRSVERTRVAEALQMLPAIYDARERLMTERGWKWGLQLVQPAVSFDKLDIDMKGKRTSDTTLLTENFQYNLVQSCAGRMCTVGEPWVSATLQKGTYKGTIVYYAGDQFTCCPGTSGSDACERLNLDKAACEFTVIPVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFH8</accession>
    <name>A0A1Y4DFH8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56439">
        <property type="protein sequence ID" value="OUO56439"/>
        <property type="gene ID" value="B5F75_04395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="21761" checksum="7B088ACCBE0385B2" modified="2017-08-30" version="1">MNPNFTREQALELLKKYNKEPFHLLHALTVEAVMRWYAQALGYAQETDFWGLCGLLHDIDFEQFPQEHCQKAPQLLAEINAGPELVHAVCSHGYGLVSNVRPEHEMEKVLFAVDELTGLIGAAARMRPSKSVSDMEVASLKKKFKDKKFAAGCSRDVITQGAALLGWPLETLFEKTIAAMRSCEQSVQQEAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFT3</accession>
    <name>A0A1Y4DFT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ORF">B5F75_01800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57532">
        <property type="protein sequence ID" value="OUO57532"/>
        <property type="gene ID" value="B5F75_01800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="115" mass="12808" checksum="26D50BAC145A6EF0" modified="2017-08-30" version="1">MKIIGLGTDIVEVKRIQAFAQKPGALERIFSAQEIAYCRARKNEYQHLAVRFAAKEAVYKALPFAGIAFKKIQVVNLESGRPEVRVEDERCQGLCILISLSHTESYATAVAVVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFT5</accession>
    <name>A0A1Y4DFT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56539">
        <property type="protein sequence ID" value="OUO56539"/>
        <property type="gene ID" value="B5F75_04925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="256" mass="29093" checksum="8F61F5F7B640251C" modified="2017-08-30" version="1">MSKTFISWNVNGIRAAEKKGFLDFLSSCGADILAVQETKACPEQLSAALQNPPGYHAFYCCAERKGYSGVACFCKEKPLAVSCGLGVEEFDKEGRTLILEYPHFYFLNIYFPNGGQGEARIAFKLRFYERFLEKSKELFKTGKTVIACGDVNTAHREIDLARPKENAGVTGFLPEERAWLDRFFTEGYTDAYRAFETSGGHYTWWDYKTRARERNVGWRIDYFMVDEKSLPNVTGADILTDVTGSDHCPIRLRMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG38</accession>
    <name>A0A1Y4DG38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase MtaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57612">
        <property type="protein sequence ID" value="OUO57612"/>
        <property type="gene ID" value="B5F75_02225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006467">
        <property type="entry name" value="MiaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01579">
        <property type="entry name" value="MiaB-like-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="119"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="45661" checksum="E73951F113EBEFBC" modified="2017-08-30" version="1">MTTFFIKTFGCRVNQVESQALLEQFLRGGYTQASSPETADICLLNTCTVTHQADKDVEKQIRQILRRNPNARLVLTGCYAAAHEAQVREKFPQAQIIGKYDLGKQLFGVEDVCWTVSGHEGHSRAFIKIQDGCDCFCSYCIVPYARPVKRSKPLADVLHEIQTLEAKGFAEIVLTGINIGNYVCPQTGADLAALCEKIAALPGRFRVRFSSIELQTVTDGIIRQMALRPDRFCNYFHLPLQAGCDKILKDMNRHYDTAAYRARVADLRRQVPQIGIFADVIAGYPTETEADFKATVAFIREVKLAGLHVFSYSPRPRTPAAALKQLPREEIKRRADALRALDKELRAQFAASLVGTEQEVFIEEHKQGRPHGITSNFQQTVLETDQPCRGLVRVRITGAEGGLCRGVLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG48</accession>
    <name>A0A1Y4DG48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57622">
        <property type="protein sequence ID" value="OUO57622"/>
        <property type="gene ID" value="B5F75_02275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011568" evidence="1">
        <location>
            <begin position="29"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="149" mass="16431" checksum="BD6B45B2FD96E11F" modified="2017-08-30" version="1">MQRPRKFYNKPMKRFGVMLASLGLAACAGQPLVQAPLGADRDGHGCIPSAGYTWSTARQACIRVWEEGITLSGVQDETAAYVVLSLDGTQAEVFLPVKTSPLILSRSFTEDGPCWTQPESPWRLLRPAQGWRLWKDGVLLYQASNPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG56</accession>
    <name>A0A1Y4DG56_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56639">
        <property type="protein sequence ID" value="OUO56639"/>
        <property type="gene ID" value="B5F75_05465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="103" mass="10889" checksum="8AD81CEEA4ED7DA7" modified="2017-08-30" version="1">MNIYVLLCLAAVAVVGLIEWVKNLVEKFLTVPGWVWSVVVLVASIGCGFLAVYGADATAHTPQMAVLFGLGVLALSQIGYDGLKTAIIKRAEKALGVDSEKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGB3</accession>
    <name>A0A1Y4DGB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_02650</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57692">
        <property type="protein sequence ID" value="OUO57692"/>
        <property type="gene ID" value="B5F75_02650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="10">
        <location>
            <begin position="104"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="224" mass="25449" checksum="9BF6AB91C57EBD02" modified="2017-08-30" version="1">MKKVFINGAEGKMGKAIARIIQSRPELGLEVSIRRESGQAVLGDFDVVIDFSTPQGAQEAFSIARKHRRPFLTGTTNLPETFLFQMQEEEKIPVFYAPNVSLSVYFFTELVRQAACMFPGYEARLHEIHHQYKKDAPSGTAKKLADVLELPYENVTYERTGEVVGTHTASFVSAFDEITLTHEAKNRDLFADSAVHIALWLMKRESGFYTMSDYAKFKLKEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGJ0</accession>
    <name>A0A1Y4DGJ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56048">
        <property type="protein sequence ID" value="OUO56048"/>
        <property type="gene ID" value="B5F75_07175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021440">
        <property type="entry name" value="DUF3089"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11288">
        <property type="entry name" value="DUF3089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="41537" checksum="D18A804FE816A722" modified="2017-08-30" version="1">MPRALYFFFFILRPNTFIYNTSQIRYIVRKQGGNLMRKLLYFFFLILPVGLCGCLGSSPVPQPAVPDYAQAENWASLPTGLADKPVDVFYVYPTIFGGAGPEQMDISDPQLRAKADVQIGINAGVFTDEANLFAPYYRQASIEVVWMKEREAEDLLKDGYRDVARAFKYYMEHFNQGRPFILAGFSQGSMALLNLMEKKFDNPQWQKQFVAAYLIGYSVTEDDLERYPWLKMAQGETDTGVIVSYNTQLPGYGYSYVLKKGAKGINPVSWKADSSVAPAALHKGAVIFDIVTGEKQAEIPHFSDVWLEEKTGALAVHADAAKYNASQAVFPPGVMHMYDYMFFYNNLKENVQKRIAAYKAAQEQHPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGJ4</accession>
    <name>A0A1Y4DGJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GPDPase_memb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02795</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56789">
        <property type="protein sequence ID" value="OUO56789"/>
        <property type="gene ID" value="B5F75_02795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018476">
        <property type="entry name" value="GlyceroP-diester-Pdiesterase_M"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10110">
        <property type="entry name" value="GPDPase_memb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="GPDPase_memb" evidence="3">
        <location>
            <begin position="126"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="351"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="380" mass="42582" checksum="B83A51132DE53C1D" modified="2017-08-30" version="1">MNLREKQNIFKLLLEGLRLVNRAGTVLFVYIIIALALNSLPWWLPHFNISPILIKLFNVLASSFLVVLLWRVLAAKADNFGESFSNSLSASVIPCFYLLLFNLLLGVACVLAILILLPMLKYLQNAGQILVSLLAFFVSVRLCFAIPAIALRAQGPVKAIIYSWEMTRGIKAFFKTMFVLLVCTALPVLCSLGILRALYVIIPLHFADSFNLAALTPGWYAVGAGCFFIIMAVGCWAFATFLLFFLNCDYGENRDSFTPEAQTQITSQTTQVFGEDNNVLPPGVGKIVTPQEAAQIQVTKASVKTVTDEKEVQQHLEQVYQPQANDVVQYTEEDRMPTILFDDEMAKQIEENRKMWTKKEEEKTSKNEEGNEGQSIKMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGR2</accession>
    <name>A0A1Y4DGR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavodoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56859">
        <property type="protein sequence ID" value="OUO56859"/>
        <property type="gene ID" value="B5F75_03160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20147" checksum="19AFDBBC8482613E" modified="2017-08-30" version="1">MAKKVLVLTGSPRQLGNSALLADAFIQGVKAAGHTAQVFETAFHPVLPCKACDKCWTTGKPCVFKDDFEKLAPMLEEADVLVLCTPLYWFNMTAQLKAAVDKLYAYMKPNAPRKLKIKECVLLSAAEGNEQDGDYEGLKATYKAIADYLKWTDRGMILAGGTWDAGDVIKTGKLKEALELGRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGU9</accession>
    <name>A0A1Y4DGU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="4">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ispG</name>
        <name evidence="5" type="ORF">B5F75_03385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56899">
        <property type="protein sequence ID" value="OUO56899"/>
        <property type="gene ID" value="B5F75_03385"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="360" mass="39172" checksum="5AD6A2AC780B1880" modified="2017-08-30" version="1">MYKTREVKVGPYILGSGHPVRVQSMCNTDTRNVQATAAQINLLEDAGCEINRVAVPDMQAAQAIGEIKKRIHSPLVADIHFDYKLALEAIKQGVDKVRINPGNIGAVENTKEVVKAAKDAGVAIRIGVNAGSVKYLKSVQGKMDLSDEKWAEVMVNEALEQANILEQLNFKDVVVSLKSDNFKRTVLANELFAKQSDIPLHIGLTEAGSFLSGTVKSAVALGTLLQKGIGATIRVSLTEDPRMQVRTAYEILKALGLREYGPNLISCPTCGRTQVDVTGTVHALEERIYSDKALLQKATGLKIAVMGCVVNGPGEARDADFGIAGGKGEGLYFEHGQTMFKLPQEKWVDFLIQKIKDWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGW5</accession>
    <name>A0A1Y4DGW5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56919">
        <property type="protein sequence ID" value="OUO56919"/>
        <property type="gene ID" value="B5F75_03490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="59"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="304" mass="34826" checksum="67A0AEFA69E065FC" modified="2017-08-30" version="1">MALLQPRGKWYSKVIEINFHFIQTAVVPNPATAVPLFIRFGFSRGKCYNSLMKSPRITLFIIAHNEESKIAKCILSARGLANEVVVVNGLSKDKTALVCRELGAQVFDRAFDGFASQKNFALSKVTSEWALNLDADETLSPQLKEEIARVIQTTDCAGFEIPFCNYFLGKKMRFSGLNKEKHLRLVRTQQARYVGGLVHEGLEANGKIGTLKHPINHYSYDSIETYFRKFNKYTSLAANQMYQNGRRFSLLFMLVTIPFEFIKRYVLKLGVLDGMRGLLWASFSTFYVWVKYAKLWQIQEQNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGX1</accession>
    <name>A0A1Y4DGX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56178">
        <property type="protein sequence ID" value="OUO56178"/>
        <property type="gene ID" value="B5F75_06060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="207"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="306" mass="34663" checksum="F1DD81357277BF02" modified="2017-08-30" version="1">MGKLINSLGRLLAERVDILIMPRMGSSKKFKVRVLTLVLVFVLWLIITLCGFLFFIRAYDYNITKADNNLMRVKMKLIADELERGRKYLDLTRTTDTQMRQMLGMPGGKFINLPKGWEEAKAKEDARFSEAMSKDLKDLDTEEFEQYIDSIEDSAKTRLASFQEIAWYFANRREGLNSIPSIRPSTARISSGFGYRLDPFGHRTTKRHNGIDFAGKPDSPIVVTADGVVRHAGWVPSYGQAILVDHGLGYSTLYAHTTQIRVKAGDVVKRGDRIATMGSSGRSTGTHLHYEVWKDGQAVNPRDYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGZ5</accession>
    <name>A0A1Y4DGZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin reductase</fullName>
            <ecNumber evidence="1">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56949">
        <property type="protein sequence ID" value="OUO56949"/>
        <property type="gene ID" value="B5F75_03640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="308" mass="32226" checksum="2B56B9BDCA0E216F" modified="2017-08-30" version="1">MIETDLVVIGAGPAGCSAAIYAVRAGIKTVIAAGAAPGGQLLQTSDVENYAGFVNPVGGFELMDNMHKQCKRLGVELTSDEIVKLEGEKTPFTLTCADGKQYKAAAVIIATGATARWLGLPEEEKFKGHGLSACATCDGFFMRGKNVCIVGGGNTAFEDALFLAQFCPQVNLIHRRDAFRADQVTVEKAKNTPNIKLVLNSVPVQILGTDAVEGVRVKNVKTGETSDIACSGLFVAVGAVPQTDFLKDSLVALADSGLVLADERTHTTIEGIFAAGDCADKHYRQAIIAAGSGAKAGIEAAAFINLHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH35</accession>
    <name>A0A1Y4DH35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LPS export ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56989">
        <property type="protein sequence ID" value="OUO56989"/>
        <property type="gene ID" value="B5F75_03840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="239" mass="27106" checksum="EC08E2E83FC3D337" modified="2017-08-30" version="1">MQLRSEQIVKVYKDRMVVKGVDIHVKSGEIVGLLGPNGAGKTTSFYMMVGFISPTKGRVFIDGDDVTSLPMYERARHGLGYLAQEPTIFKGLTVEENLLAVLERILDDRQEQKRRVDELLNEFGLTKLAKQKAWTLSGGEKRRMEIARCMISNPKIILLDEPFVGIDPITVSDLRHMIFKLKDKGIGVLITDHNVRETLPLTERAYLIYDGKILVEGDQNTLLNDPNARRLYLGEDFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH76</accession>
    <name>A0A1Y4DH76_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57029">
        <property type="protein sequence ID" value="OUO57029"/>
        <property type="gene ID" value="B5F75_04065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="101" mass="11369" checksum="2934B17998A0FBE9" modified="2017-08-30" version="1">MNEKQLKKRNACDLQAVLKTVQGRRLLWRILQAAQIGQHGFVPGDPYATAFHCGQQSIGLFLLAQITDAAPAAYLQMRGEYLSQVQSEQNEINRQQEELNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHB0</accession>
    <name>A0A1Y4DHB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57069">
        <property type="protein sequence ID" value="OUO57069"/>
        <property type="gene ID" value="B5F75_04270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="62" mass="7002" checksum="3399760D307B48BF" modified="2017-08-30" version="1">MKNGAGKKRFLNKKGQTAVEYIITAAGLFTAIISFYVLYSYMVPEQFEEGAKVILMEYDASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHT3</accession>
    <name>A0A1Y4DHT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56498">
        <property type="protein sequence ID" value="OUO56498"/>
        <property type="gene ID" value="B5F75_04705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="24"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="337" mass="37475" checksum="1111E1C8B10DA648" modified="2017-08-30" version="1">MQINDLGVVLLLALIVFIIVIITKGIVIVKQAQVIIIERFGKYLQILTPGINWIIPIMDKPHLMEWRENRDYMDGSGRVRSVPITEMRNVIDMRETVYDLPRQSVITKDNVGIEINALLYFQITDPINAAYKVESLPTAIEKLTQTTLRNIIGEMDLDQTLTSREIIKSKLQVILDEATNKWGVKVNRVELQDIIPPAAIREAMEKQMKAERDRRAMVTEAEGTKTAQILKAEAVRESEIKKAEGMKQAAILEAEGISEAKIKVAQAEAEAVKIVASTVAQSSNPASYMISLKYIEALTKMTEGKDNKIIYMPYEASNVLGAVAAIKDLTGGVPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI30</accession>
    <name>A0A1Y4DI30_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57319">
        <property type="protein sequence ID" value="OUO57319"/>
        <property type="gene ID" value="B5F75_00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018385">
        <property type="entry name" value="C4_dicarb_anaerob_car-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018387">
        <property type="entry name" value="YcgA/YfcC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43652:SF6">
        <property type="entry name" value="PTHR43652:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03606">
        <property type="entry name" value="DcuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="464" mass="51174" checksum="F0327FC6A00C6239" modified="2017-08-30" version="1">MKKMLCNTYFLVFSIMVFVAALTWIVPSGLYDRVEADGRTYAVAGSYHSVAKNPQGIDAVLSAPVEGFTQCAEIIAFILVVGALFTIIERTGAINTLIKKVSFFFASRPKYKKLFIPVCMFLFSLCGAMFGMEEETLIFIPIFIPLALSLGYDTVIGMSIPFIGAFTGFSSAFVNPFTVGIAQTIAQLPMYSGWQYRVVIWFIFTSVVAGFFTWYGERVRKNPTKSLTYKMDLDKRAELKIINDVVVDESFRLTRAHKRVIASFVLGMGLLFYGVIRYQWYMIEIAAVFLGVSIACAYFGKLTLDQATNAIIDGAKSMIGVCILMALARSIVIVATNGHILDTFLHAMTQSVGGLHPILASQAMFVIQTVLNFFIASGSGQAVLTMPIMVPLGDLVNVSRQTVILAYQFGEGWGNPIIPTAPVTMGALALAGISYPMWVKWFLKLEVILVALSLILLIPAYYIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIG0</accession>
    <name>A0A1Y4DIG0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57449">
        <property type="protein sequence ID" value="OUO57449"/>
        <property type="gene ID" value="B5F75_01365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013368378" description="Metallophos domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="152"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="44744" checksum="0C2B3472B4E7E6FA" modified="2017-08-30" version="1">MKKILLFSLLCTLGASVQAAQIIRGPYIEDPTQTTMILRFQTDETTPAWLEYGPAPRCNQIMTLTPAGTQHKAILYGLVPNQDFCYRIYVNNAAGDGVQEPVSGSFRTLYSAERKVVNFLVLGATGADMPLPLPDGTPVVDEAAQARSQLAALMEQEESDFLIHTGNITHSGLNEDADREFFEPFKNVLAKNPLFVALGPNEYGPDRENRESKSFLRTNYSRYHDMSWSNATPKYYSFDTANARFIFLDTNVAEGAVWGPEIGEDSAQVKWLKSMLSGAGEKWKIVVMNAPAYSTGQRGPNNEVALNLIKIFENYGVKLVIQGGDPDYERTFPMYRGEPNPRGVTYVTLGTSAPTPGKRAHSDASTARFVAARHYAAGKIVDRKLTLTVYNNLGKELDTLEIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIG8</accession>
    <name>A0A1Y4DIG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56110">
        <property type="protein sequence ID" value="OUO56110"/>
        <property type="gene ID" value="B5F75_05680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="18"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="278"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="534" mass="58413" checksum="19D8D3D08E25C067" modified="2017-08-30" version="1">MIELFEDPSQDKPSDQPAPASLVKFRQVSQDALKGAGEARIKAQKDKGKMTARERISYLLDKDSFLEIKSLMESSCSDFGIKDKHIKGDGVITGFGRINGREVALFAQDFTQMGGSLGLAHAKKIAALMDRAIEAKIPLIGLFDSGGARIQEGVDSLNGYGEIFYRNVKASGVIPQISVILGPCAGGAAYSPALTDFIFMVEGISHMFITGPGAVKAATGEEVDFDTLGGSRPHSEKSGVCQFVAKSEQDCFRQVRELLSFLPQNCNEKPPLDTTSDLVERSVPVLERVCEMDPKKAFRIHHVIWRLADDYGFFEIHQNFAKNIVTGFIRLGGHVVGVVANNPACLGGALDSDASDKAARFIRFLNAFNIPLLTLVDTGGYLPGVQQEHGGIIRHGAKLLYAYSEASIPKVTLVLRKAYGGAYIAMGSKYLRGDFNFAYPSAEIAVMGPRGAVEILYSRDLKKEEDPAKKEEMKQKLTKEYSDKFASPYQAATNGSIDEIIEPAETRTKIIRAFEVLKNKRDPRKNPHKGNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DII6</accession>
    <name>A0A1Y4DII6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56130">
        <property type="protein sequence ID" value="OUO56130"/>
        <property type="gene ID" value="B5F75_05780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="11510" checksum="A17188F0B01812F9" modified="2017-08-30" version="1">MTQDLKATLLRNKKPLLLAFGLAVVVVFFLGSSFLSLVHNKLEMRKLAKQSIELDEQHQELLRKMERLQKQDLTYIEEIARTQYNMVKPGEIQFRFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIQ0</accession>
    <name>A0A1Y4DIQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proB</name>
        <name evidence="10" type="ORF">B5F75_06120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56190">
        <property type="protein sequence ID" value="OUO56190"/>
        <property type="gene ID" value="B5F75_06120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="289"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="380" mass="40480" checksum="3AD24C2939422F90" modified="2017-08-30" version="1">MKDLIKQAKRIVIKFGTNALTTESGDLALSRLYSFIEDIAALHAQGKEILVVTSGAVGLGKKRLGLTSAPDVLALKQACAAVGQISLMKFYEDGFKQLGLVAAQVLLTEDDFSHRSRYLSLRDTLNRLLELGCIPVINQNDTVSTNELRGYKEKGIKVCFGDNDKLSALVASGMDADLLCVMSDVDGLYSGDPRKDKNAKRIDVVKGVTPEIESLGFCASSRGRGGMKTKLEAAKVVTRSGAAMVIAYGKRPGAVSAVFGPDFAGTLFLPVEDLPGKKLWLAYATNVAGGVTVNAGAKKALCQKGSSLLPAGIVAVGGEFEAGDAISILDEHGVEFARGLANYSDKECRKIAGCRSEEIAKKIGYKNYDEAVHRDNIVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIW8</accession>
    <name>A0A1Y4DIW8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56260">
        <property type="protein sequence ID" value="OUO56260"/>
        <property type="gene ID" value="B5F75_06480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="1">
        <location>
            <begin position="156"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="319" mass="35118" checksum="0FE41D32306C293D" modified="2017-08-30" version="1">MVQHASWQSPVLNAFHTPADVERESFTDGIRTELSAPIQTAFPFASLVFSLNYAAPKDSFILLEAQVLEEGKWSDFFKLGLFSQGIKKSFPSQDSAFGRVETDELALARPAQAYRYRIQFCGEAKLTLLAASAVRSPFEYEENKAARLPAGHFQKEIAPISQMELNHPDRRRVCSPVSLCMALNALGVACSAEEVMQGVYDASANIYGNWVFNTAYAGSCGVQAYVRRFGALSELKDFVTPDSLVLASIAYERGELTGAAMERTAGHLVVVCGWENGAVCVADPAALKKQTVLRAYNAREFANAWLRHKRGAAYIVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIX4</accession>
    <name>A0A1Y4DIX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_57 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 57 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56270">
        <property type="protein sequence ID" value="OUO56270"/>
        <property type="gene ID" value="B5F75_06545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021923">
        <property type="entry name" value="DUF3536"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027291">
        <property type="entry name" value="Glyco_hydro_38_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004300">
        <property type="entry name" value="Glyco_hydro_57_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12055">
        <property type="entry name" value="DUF3536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03065">
        <property type="entry name" value="Glyco_hydro_57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_57" evidence="2">
        <location>
            <begin position="110"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="789" mass="89238" checksum="36EB51C3AC62DD77" modified="2017-08-30" version="1">MKYLCIHGHFYQPPRENAWLEEIEQQDSAAPFHDWNSRICAECYSPNALARLLDGNKNLIDLANNYAHISFNFGPTLLSWMEKNEPEVYQSVLEADKLSRERFGGHGGAIAQVYNHMILPLANARDKETQVKWGIADFEKRFGRKPEAIWLAETACNTETLEVLAAEGMKFVILAPGQCKRIRKIGEEKWQEVGAGVDPKRAYRCNLPSGRNIALFFYDGPISQGIAFSDTLSSGEKFAARLLGTYNAGGEPQLMHIATDGETYGHHQKFAEMALAYCLKKVEETPDVELTVYGEFLAKHPPLYEAQIVENSSWSCFHGVERWRADCGCNSGMKPGWHQKWRGPLRQALDFVRDEMIKTFETVGSQYFKNPWDARNDYIDLVLDRSLDAQHRFFLKHATEKAWNDRPTALCLLEMQRNAMLMYTSCGWFFDEISGIETVQIMQYAARAIELNRAISGVDLEPAFVEKLSAAPSNLKELKNGAVVYERYVKPQVMPIEKIALEHVVSLLADDTVNPQKAYECDVLAYAPKKLAAPGFHLCFGDITLKSRTTLLERKMHFAVFQHGATDFLCAAGTEGTLDRGAVFGQLEELFQAAKYEDCAALIRRSFPKQYPLSSMFLDVRRKVVDLVLRKMDEETDQKFTKVFEDQYPVVRGLQLIGAPIPKPFLTVAEFVLSNDLKAEFRAADVNVNEIEELMEDVKTLGLDVSKGPVREAVSEKLERLAFAFARNPSDTACALKLVEFLNYAEIFGFEPDAVRAQEFVFFGLRALGEEAKKKDILRALARKLKIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ04</accession>
    <name>A0A1Y4DJ04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-methyl-2-oxobutanoate dehydrogenase subunit VorB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56300">
        <property type="protein sequence ID" value="OUO56300"/>
        <property type="gene ID" value="B5F75_06705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="2">
        <location>
            <begin position="249"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="387" mass="41591" checksum="CBE13F3327268AC7" modified="2017-08-30" version="1">MTEKTLRKGNEALAEGAIRAGARFFAGYPITPQNEVPEYMSAYMADAGGAFVQAESEVAAINMVYGAASTGTRSMTSSSSPGISLKQEGITYLASADLPCLIVNVMRGGPGLGSISGSQGDYFQATRGGGNGDYHVIVLAPNSVEELGNFPKLGFELAEKYRMPCMILADGILGQMMESMSFNFDPIDPNKLGKFDWAVDIHKNGRKKNNVFSYKGDNLIADVVERAKRYGLIEKTEARWEERDAEDCDVLLVAYGLSSRACLEAVNKAKEEGLKVGLFRPITLWPFPSKRLAELAAKAKGVLSVEQSLGQLVQDIKLAVNGKTPVYLNAYPAGGQPDGNTILTAVRSILNGGKEGLFDLQEHAAGFSYECKRDTSLGMQGDLKGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ08</accession>
    <name>A0A1Y4DJ08_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaA</name>
        <name evidence="13" type="ORF">B5F75_02425</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57649">
        <property type="protein sequence ID" value="OUO57649"/>
        <property type="gene ID" value="B5F75_02425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="149"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="12">
        <location>
            <begin position="360"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="157"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="455" mass="51566" checksum="E4B2871619AEF456" modified="2017-08-30" version="1">MENLQAYPQLIPVFQDIENIIGKDPYDMWLRPAQFIYEGNTLTITLPNQFWGKTIRERYETIITDAFLKHLGAEITVVYAVSAQAAAPAVNSAEDVIPAAPAPAPVIKKNPFPSRLNSSYTFDNFIESPSNRFAYKAAEAVVHKLGNRENNPLVIYSAPGLGKTHLLHAIGNQILKENPDARVLYMSGEEFVSEYIEALQNKSSESFRKKYRSLDCFLMDDIQFVAGKSASEIEFFYTFNALFESRKQIVLSSDRTPQQLDLDERLSSRLLSGIIAEVKRPNLETRIAILRQKRDSINFDIGDDVLSFIAEGIQTNIRELEGSLFRLVAYCSMHGVTPTIAIAKELLADILTNETDLNINVNVIKKIVGKHFNIRMEDFNSKRKTQSIAWPRQIAMYLTTELTDLSLPEIGREFNRDHSTVVHARDVVKEKIEQDPFFAAEINQIIMDIKAVDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ13</accession>
    <name>A0A1Y4DJ13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glycine dehydrogenase (decarboxylating) subunit 1</fullName>
            <ecNumber evidence="4">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glycine cleavage system P-protein subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine decarboxylase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine dehydrogenase (aminomethyl-transferring) subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gcvPA</name>
        <name evidence="5" type="ORF">B5F75_06760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvP family. N-terminal subunit subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56310">
        <property type="protein sequence ID" value="OUO56310"/>
        <property type="gene ID" value="B5F75_06760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00712">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006815">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="442" mass="47969" checksum="27830E7F73A20CF3" modified="2017-08-30" version="1">MFIAHTSQDREEMLRKIGVSSVKDLLSQIPQELLYPALGLPKALTEQELTAHVHELAARNQPLKNFIGAGIYEHFIPAAVGALSSRGEFLTAYTPYQAEASQGTLQTIYEFQSCICSLFDMDVATASHYDGATALAESVLACLRITGRSEILISAALHPHYKEVLKTYVRHQKGVCVKEIPFQQDGTLDLEILSQELSEKTACFVLPNPNFLGCLEHAEEISSRVHQAGALLTAVVNPLALGVLQTPGAYNADFAVAEGQPLGNAMNFGGPGLGIMTAKKMYMRQLPGRMVGIAKDKNGRRAFVLTLQAREQHIRREKASSNICSNEALCALNAVIYLTLLGPQGLREVAELNLERAHQLADLAGNIPGFRVKFTAPFFNEFVLECPIPAQQVIKKLAKKGISAGYALGTDFKELKNCLLVCATETKTAADLQAYADALGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ69</accession>
    <name>A0A1Y4DJ69_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">B5F75_06970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56350">
        <property type="protein sequence ID" value="OUO56350"/>
        <property type="gene ID" value="B5F75_06970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="210" mass="22635" checksum="AF5CEAB32ACB29B2" modified="2017-08-30" version="1">METKVLDIKGKEKGTCALPDSLFAVKANPTFLHEVITAFLANQRSGTADTKTRSEVSGTGKKPWKQKGTGRARQGSLRAVQFRHGGIAFGPTPHSYRQDLPAAKRRTALAMALSTKLAEGNLVVLDSLTFKEPKTKAFAEVLETLSAGRKPLVLDNFADANAALACRNVEGLTHIPTQDINAYVVLNSTKVILTQAAVEKLCETFAKEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJS8</accession>
    <name>A0A1Y4DJS8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56590">
        <property type="protein sequence ID" value="OUO56590"/>
        <property type="gene ID" value="B5F75_05200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="79"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="544" mass="61258" checksum="ADD716AA3BCFA47B" modified="2017-08-30" version="1">MPDKTVKKYLSLHLPSVLLLLLLMLLGGLYSVWLGIDVNFDLLNYHLYNPYALLNGKIGQDVFAAGVHSALNPLPDVYLYGLFSAFFNSPKWIGFFMGLPYGVLIWLVYRLARDVFSRTQYPKTYAAVAAFIGCSAAGIMSQVGTSTNEIPLAVFHILAFWLLLRAVQQPQKTYGVYMAALLSGATAGLKLTGASCCVALTAVLLVYLTRFKKPGKVFMLYALCGILGFLLTNGYFMWQNFTLYGNPVFPYYNTVFHSPYFDNVNVTETRFFPTTWAQWLFYPFFWAFAPGTYVSEAPVQDSRLALFLAALAGWGILIAKNKLGGVKKEAAVSVAVYSGVGYVVWLVQFSILRYAAVLEALCGLVVVGVCAAIHKTRWGGYAALLCVGISMWGYQAPDWHHEMFLEQAVIFDKKPKIEDNSLVFFMHLPSSYLAPLLNPKAVYMGGFLSKPEEYPEQFRRQAAQRNNISAQYYRFRFEELQRDKIARHQGPIYIVSVDWPMIVNPATLARFGLKGKREDCQRFVTNFTVYSKDLAICRVQKIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJU7</accession>
    <name>A0A1Y4DJU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ORF">B5F75_00045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57208">
        <property type="protein sequence ID" value="OUO57208"/>
        <property type="gene ID" value="B5F75_00045"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="293"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="482" mass="54272" checksum="475CE455A255F8C7" modified="2017-08-30" version="1">MNIVLAASEAFPFCKTGGLADVVGALCQQFAMRKGNKVLLFLPHYRSIVRVSSLKVVPGVYLIPIGDRIEQVSLSYINWGNVLVFFVGSRKYFDRPELYRTKTGEFADNDERFILFSRAVLEGCKFIGFRPDIIHCHDWQTGLIPAYLKTVYKLDAFYTRTRSLYTIHNIAYQGHFPYSTFKKAGFHPVDYTPEKFEYYGGISFLKSGIVFADNINTVSPNYAREVQSDPAMGFGLEGLLRYRSKNFCGIVNGIDTEVWDPEIDPVLPIGYDAAEAVKGKLAAKLALQQQCKLSQDPDKPLIGIVSRLDYQKGLDTVVDLIGRLKDRVQFVVLGMGDPMLEKAYQSLARNNPASVSYNGRLDEDLAHRIYAGADIFLMPSRFEPCGLSQLIAMKYGTLPVVSKVGGLVDTVKGYQPGKEDTATGFFIEEFTEHGILQAVEGALAVFNDRKRWNRLVRNAMRQDLSWDKSAQQYLELYRKTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJZ4</accession>
    <name>A0A1Y4DJZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56650">
        <property type="protein sequence ID" value="OUO56650"/>
        <property type="gene ID" value="B5F75_05520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="135" mass="15123" checksum="797AB4ECF67C7EC1" modified="2017-08-30" version="1">MIENIVLKVLKADSALAALVSTRIYPDMAQVKTLPAVVMSADEPTSPINEPWAYTQNLTFNIYAKTIKSAQDVRNRIYDILQQYDTFFCADLAKSGIIIHEAHAVMGSVSNHFPLDTEQAQEKVVSFDFYFTKCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK10</accession>
    <name>A0A1Y4DK10_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_00310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57258">
        <property type="protein sequence ID" value="OUO57258"/>
        <property type="gene ID" value="B5F75_00310"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="25"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="82"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="273" mass="29531" checksum="8BD46221BE5D4CB7" modified="2017-08-30" version="1">MTQLAQVKKAAAFLNKKTKNFKPEIALITGSGLAGSIPPLEKEIKIPYSSIPGFLQSTVPGHSGNLIFGVYKGRKLVVMQGRFHYYEGHPMKDLAISIRTLKLLGVEKLLVSAAVGSMDLKLKPGSLCVLKDHINFMCNNPLIGNHDPAFGPMFFDLSEAYDKAMRKTALAAAKKVGVTAGEGVYLAATGPNFETPAEIQMFKKWGATVVGMSVVPEVLVARQCGISVLGLAWVSNMGCGIEKKPLSHAQTISETKKIEGKFKKLLEILFVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKB7</accession>
    <name>A0A1Y4DKB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ORF">B5F75_00935</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13 14">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12 13 14">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="domain">
        <text evidence="12">Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57368">
        <property type="protein sequence ID" value="OUO57368"/>
        <property type="gene ID" value="B5F75_00935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="252"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CHC2-type" evidence="12 14">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002811-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OUO57368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="582" mass="64836" checksum="30BB9EC09801B49B" modified="2017-08-30" version="1">MNNNIVEQIKDRLDIVEFIRQYVPDLKRAGKTYKACCPFHKEKTPSFTCSSEKGLFYCFGCQEGGDIFAFLMKMENLSFNEALEKLAGLAGVEYKPAKPLTGEEIRRANARKLLDFAKAFYHKNLMSAGGEYARAYVKERNLTKETCQKFELGLAKNEPTALAREAKAAGYTDKDLKDAGLCVLTSYGPRDYYRNRLMFPIINQRGDTVGFGGRILGEGEPKYLNSPETVLFTKSHILYGLNFAGPAIRKAGRAVLLEGYMDVIACHQAGVEYTVAPLGTSLTEDHARLLKRYTDNVVVLFDPDAAGIKAALRGALILIERGLFVKVASLPEGLDPDEYIAKYGKESFETVLNQAEDLIAFHTRLQLGLYPQPMDAQNKTRVISELAETIAKQPDEIVRREWAKYVAEHVGVDEQLVLERLRKPALQPAYARRQPAPSAGAAVASAAEEDLLSWLLKSPQHTVLCCELSQEDFSTAAAWKIFQAVVQAHGEDPQAANLAERAAQKVPEYKTELVKLAMLQAPADFDPARDIAACAAKLEQAGLHKRLEAVRRQMKQLGAGNVPQEVFQKYMQLQNKLKKYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKG9</accession>
    <name>A0A1Y4DKG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56790">
        <property type="protein sequence ID" value="OUO56790"/>
        <property type="gene ID" value="B5F75_02800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="416" mass="44506" checksum="AC4C991E181108A0" modified="2017-08-30" version="1">MLSKNQFHQAETGLFCYSIFMNTPQDFKNTVFHTAIIGAGASGLMCAGSFAQSKILIDRNAKFGVKVGVSGGGNCNFSNRFVSAADYLSQNKHFCKNALAAFTPQDFVDLLHAEHLPFEERADGQLFSFGAVPIVQMLVRRAKAAGTQFLPNTQALDVRLENGLFTVVTSEGPVRAQHVVLACGGLSFPALGASNFGFKMAQKFGLPVVETRPALVGLTFPKPLQARFRQLAGSSLSAVVSCGKHAFEGQLLFTHEGVSGPAVLQASLYWTPGQSVQIDFLPHINALEYLHAQKNKVHSFAAALHGKLSAKTAKTLLAPWEGDLPNAPRPQLQAAAQALNHFTFVPAGTAGYTRAEVTAGGVDTRAINPTTLEARDVPGLYVIGELLDVTGRLGGFNLQWAWSSGFAAAKALEKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKS5</accession>
    <name>A0A1Y4DKS5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proS</name>
        <name evidence="10" type="ORF">B5F75_03390</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56900">
        <property type="protein sequence ID" value="OUO56900"/>
        <property type="gene ID" value="B5F75_03390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00779">
        <property type="entry name" value="ProRS_core_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033730">
        <property type="entry name" value="ProRS_core_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="33"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="574" mass="63996" checksum="7B908DF115AA662B" modified="2017-08-30" version="1">MKLSNYYLPTLKEAPKDADTLSAKLMIRAGLIRKVASGLYEWLPLGLKVLKKVETIVREEMNRAGACEVWLPLVQPKELWEESGRWTYYGKELLRFADRKEAEFCFAPTAEEVMTDLVKKDTTSYKQLPFCLYQFGTKFRDEIRPRFGVMRAREFYMKDAYSFAANDADANDWYQKMYDAYQRIFKRCGFEFKAVEADTGAIGGNFSHEFMVLADTGEDAIANCPACGYAANTEKAEIQAPADLAINEADLKPMEKRDTPKAYTIEDVAAMLNVPTSQLIKLLVFTADGKPVVALVRGDHELNEFKFKALLKCNELEKASEEVYTQVTGSFVGFAGAQGLKEKNPSVMIYADNYVKNIVNGVSGGNGKDVHMINVTPRRDIKVDVYADLKMASAGDKCARCGKEFTFTRGIEAGHVFKLGTKYSASMGANFLDENQTSKPMIMGCYGIGISRVVAAAIEQSHDENGIIWPAPLAPFDVALVAIDYASNPEVKKHADAITEQLEAAGLSVLLDDRDERAGIKFKDMDLIGLPHRLVVSSRTVKDGQCEYKKRTEKESVRWNLDEAVKKLLQAAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKT9</accession>
    <name>A0A1Y4DKT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57548">
        <property type="protein sequence ID" value="OUO57548"/>
        <property type="gene ID" value="B5F75_01885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="20523" checksum="01F2954F1B07B0E1" modified="2017-08-30" version="1">MKHYSKLKETKISSKTLYRGVLGVKLDEVKLLNGRTSTRLYFDHHGASGILPVEDGSVYLVQQYRYPIRQATWEIPAGKREKGQSFLACAKAELKQETGLTAESLKEIMVFHPCNAFSNEEQHLYLATGLTRGKDQPDEDEFLNLQKFPLEKAYKMIEKGEITDAKTIITLQWYRIHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL71</accession>
    <name>A0A1Y4DL71_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57678">
        <property type="protein sequence ID" value="OUO57678"/>
        <property type="gene ID" value="B5F75_02575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="2">
        <location>
            <begin position="4"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="471" mass="50915" checksum="067E8925D1A3D859" modified="2017-08-30" version="1">MNINRLVHPGFWFGKTPQEEALQLARMGVGGFCLYGGTRAEVAALTQALRAASPHKRILISADYEDGLGRWLPDAELLPSNLALGAADDTALAEEKGFLTARQAKSIGVDWVFAPVVDLADHPQNPIVNTRSFGADPQKVTRLAGAFMDGLAKGGALNSLKHFPGHGNTATDSHLALPVLLSTKQHILTHELVPFQQLLNKADAVMVGHLLVPTLDEQYPASVSHTLMTDLLKKQMGFAGCVCTDALGMKALGDEKKAALKAFLAGAHILLVPEKPFELLDFLNKQTLPPALLEQAMQQQNFLCARADEVPCTTQAAAFGPTDFSARTAHKALTLLGAPLTLTAGETLYYLSVGNDEHLSQEPFLQALQQHHIKTEAFNGQEGKLAVLCWRRYQAYKGKIGLDEQEIQQVKQALQNHPHSIAISFANPWTVDNIPCRGKLFAFSPAPAFQQAAADVLAGKLTPQGKMPVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL80</accession>
    <name>A0A1Y4DL80_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56171">
        <property type="protein sequence ID" value="OUO56171"/>
        <property type="gene ID" value="B5F75_06015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="15365" checksum="5D18E1CCB4E2C319" modified="2017-08-30" version="1">MKKGFTVTEILITVVVFALLLGFTVPKFLMLVHKAQEGSTKHQLVKVRSAIAAYYGEHQGTYPTDDLSSLVPTYIESIPQAIIPGYTPSSHVSVGNFEQCFTKTGGWAYVNDPTDPRYGDFFVNTDKEDSYGKPWNTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLP1</accession>
    <name>A0A1Y4DLP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57220">
        <property type="protein sequence ID" value="OUO57220"/>
        <property type="gene ID" value="B5F75_00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="342" mass="40575" checksum="4B74F0E75DB8B166" modified="2017-08-30" version="1">MEFEPITPAFASTPYVIGMSSSNRYAPYLAVYLQSIIDHAKEENRYDIVIFETDMTADNKARIQALAQLPNFSIRFYNLKTAFENNLYISLHYFAKQCYYRLALGEVFKQYEKAVFTDIDLVMVADIFDLFKIDLQGQPIAACEEILWTPSRRNQQVSRTQSIDSYLKEIGCTGLYYNTGVVVADVAKFNETASFRQLLQTAQENKFMNLEQDVLNKVFNNRFYTLPPCYNFEVINSVFEGKTEDFRVYAAQVEQARAYHFLAADKVWFFPNVPKGYLWWQVARKTSYYEEILAAYVNFYCWHFVPYYLKYKKYHFFAKFVFGKMKQRYLRKAAEYWNWLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLZ9</accession>
    <name>A0A1Y4DLZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:phosphate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57320">
        <property type="protein sequence ID" value="OUO57320"/>
        <property type="gene ID" value="B5F75_00655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018212">
        <property type="entry name" value="Na/solute_symporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00456">
        <property type="entry name" value="NA_SOLUT_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="475" mass="52559" checksum="BC060A391008D489" modified="2017-08-30" version="1">MLNELKTVSYFHWADWAVFFAVLAATAGAAIYGNRRLKKKQGKKPVSVLDYLLMGRQLTLPLFVATLVATWYGGIFGVNEITFNYGIYNFVTQGLFWYAAYLIFAFFIAEKVARYQSMTLPDLTGQMFGPKSAKVAALFTFFYITPVAYVLSLGMFLHMVFGIGILPGMALGTLFAGLYTAWGGFRSVVFSDLVQFFVMCSAVLLVVVFSVGTFGGLDFLKAHLPASHFTLTGGNSWLNTLIWGFIALSTLIDPSFYQRCFAAKNPSVVKKGVLISTFIWFCFDLCTTAGSLYARALLPQAQPGQAYFFYAIQLLPVGLRGFFVAGILSIILSTLNSFLFIASNTLSFDLLRNRFKNVVLSNRIAIFAVGILAILMAHLFHGSFKEIWLVLGSYFSACLLVPILMGYLSPGRISDGLFVFSSLASAAAMTAWRFVRKHEVLEAVDPFYIGVATGLVILILLRRSKNASISRITYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMK1</accession>
    <name>A0A1Y4DMK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_S9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57530">
        <property type="protein sequence ID" value="OUO57530"/>
        <property type="gene ID" value="B5F75_01790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="97"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="299" mass="34143" checksum="54FC3170280DABC9" modified="2017-08-30" version="1">MTSVLYILLIVLGAALLLCLGTVVFCMHAAKRVLHPVSKRKALDAWPDQFGLPYENVYFKTEDKVQLKGWFIPSEAYSNKTIILMHGWGMNRADILKNTYFLHDLGFNLLYFDFRALGESGGKTSSIGYLELKDVAAAVRFLKETRPQFCEKIGLYGLSMGGMVAICEAARNPDIACVVAEASYYSFRRVVSRWAWVHHRVPYFPLIPIILHYIHKYLGVNPERYSPKYNIPRISPRPVFIIHGRYDNLVPAAQAKLLFKKAGEPKEIWLVPGAKHNKCAEVGGFEYKQRLADFFRQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNJ3</accession>
    <name>A0A1Y4DNJ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56971">
        <property type="protein sequence ID" value="OUO56971"/>
        <property type="gene ID" value="B5F75_03750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="142" mass="15679" checksum="87029F5702BE7152" modified="2017-08-30" version="1">MWKNNKGAALLQVLLITVILAGMATMLLRASLSRVTAARKTRRTVSAQMLVNSCMAEVNTLWSIKNSEAFSRDLRQCIMYCNSTNVTSACSTANSVRTHTCHIPVNGKTYDVTAEFTTTYPTADNARKCKLTYTIESDTDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNS0</accession>
    <name>A0A1Y4DNS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57041">
        <property type="protein sequence ID" value="OUO57041"/>
        <property type="gene ID" value="B5F75_04125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="144" mass="16287" checksum="FEDCDF6DE6C25F4E" modified="2017-08-30" version="1">MPAKTRARTLKTREKPLKYQPEFCERLLRFFDVAPFTVTEVAKRDGSISLVETAAELPTFAAFAKMLGTTCRVLKEWEEKHPAFRQAAAKARDLQGNILIQNSLRGNYSASFAVFTAKNLLGWKDGKEEPSQPAPLVVRWESEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPE5</accession>
    <name>A0A1Y4DPE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57261">
        <property type="protein sequence ID" value="OUO57261"/>
        <property type="gene ID" value="B5F75_00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="340" mass="36487" checksum="9AF09ACAB748109F" modified="2017-08-30" version="1">MKTFVLYLLCMLTAGVITAASLPLLRRLSAGKLLDAPGGLKQHRGSVPVLGGSGILIGTLASLVLIRFCTAFPSGTLHNLRGIFIGGACIFALGLVDDFKKPKGVSVATKLLVQALAAGALIYYGVSIHAFTSPWISWPLTFLWVVGLTNAFNLLDIMDGLCVSQAVVCTLGLAVIALPSEYVYVNFAALALLGACLAFWPYNHAKRKIFLGDSGSTFLGFMIAALSIGTGYSERTSWGFLAPLFILAVPLFDTAFVSLARILKHKNPLKGSNDHIALRLKKLHWKSPFILLTFAAAGLFFNIMAFTLTHCCIEIALALFVFSALALGLIAVWLLHIKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPK9</accession>
    <name>A0A1Y4DPK9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57321">
        <property type="protein sequence ID" value="OUO57321"/>
        <property type="gene ID" value="B5F75_00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="SSF63862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="SSF63999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPK_catalytic" evidence="6">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="TPK_B1_binding" evidence="7">
        <location>
            <begin position="148"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="22500" checksum="9371C4E5548155C7" modified="2017-08-30" version="1">MPAFHALLIGNGQTDDSAFLKTLAAQAQLVAAADGGADRALQAGLTPDVIIGDLDSVSARAKHAVRPENLIFVNNQNNTDLEKALDWLCARGVSSCTLVGFMGGRWDFTLGNFLSVVPYAKKMALAFAGPGWKFYPVYKSRRFACRPGARVSLIPLRVCRGVSLKGLKYPLQNARLHLGGTGRTLSNQTTGKTFSVSMQSGFLFVYAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPT1</accession>
    <name>A0A1Y4DPT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57371">
        <property type="protein sequence ID" value="OUO57371"/>
        <property type="gene ID" value="B5F75_00950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="226" mass="24618" checksum="CA81A534395A11C2" modified="2017-08-30" version="1">MDLEAISTQVSAHLLQVGQSSLKVLAALVVAVLILVIGLYISRFVGSYVKKILNKISFDDKTSKLGINELCVRFGLGKSPTYIISFVLAWAVIFYAVVLAAEVLHLDIIRNLFTQFLEFIPTLFVSVLILFAGLLFGKLMGNIIENSAQANNLKGGFFISKAVNIFIVFFCALIAVENLGFANQLVNNVVIIVLASLGLAFGIGVGLGSKELVADFLRELFKKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ05</accession>
    <name>A0A1Y4DQ05_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57451">
        <property type="protein sequence ID" value="OUO57451"/>
        <property type="gene ID" value="B5F75_01375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="16"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="250" mass="27646" checksum="3FDBC189B4113091" modified="2017-08-30" version="1">MNEPNDITVTSRALSLISHKLKTPLSIINGYSEAILSQAKKEKFSPFTSKALEEINKQGGRMSLLVDKLMAFNKVTAAQTEGIEKQTVYLKNLIKDCAAKAIAQEEETPAPAPVTDDTSVKRGTFVEIDCPEHLSVTANEEMLRLCIRELLANAIKFNNKMEKIIKVQCANHGDTISISVRDYGAGIRPQDVNRIFEPFYQVDDYFTGQISGWGLGLPMVKRILDLHDGSISVVSDRGLGSIFTINFPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ53</accession>
    <name>A0A1Y4DQ53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57491">
        <property type="protein sequence ID" value="OUO57491"/>
        <property type="gene ID" value="B5F75_01590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="99"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="239" mass="26560" checksum="E4D59EC4FDAD7646" modified="2017-08-30" version="1">MARDFLETYLNKPRSFLFVIGLVLLGLAAWGVMLWRLEAPAPVRPVILLINRYPLTPADKSFLQQANPYGFLLGIPAHPHLDPRRLRQELAEVLHRADFVFFIDQEGGTVNRIKQYDPSFQAPAPEVFGKQAETNLPQAIEAAYQYGVRTGKFLKNLTIDVVFAPLAEQRPTGPNAPHKSRYFSDQPALVQALADAYARGLADGGVIPCYKHAPGGSAQYEKQTVELPALEIQSKLLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQH0</accession>
    <name>A0A1Y4DQH0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">glmU</name>
        <name evidence="17" type="ORF">B5F75_02220</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57611">
        <property type="protein sequence ID" value="OUO57611"/>
        <property type="gene ID" value="B5F75_02220"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="10"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="263"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="398"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="417"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
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        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
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        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO57611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="467" mass="49889" checksum="E7CE81E384C8A5E9" modified="2017-08-30" version="1">MVAKKNLCVLILAAGKGTRMKSPLPKPLHIVCGLPIIAHILKAAQALGPAAIGIVVGHEAQTVVNAIQAGLSQWGITAPVVFVQQTELTGSASAVKAAIPLLQKFETVLVLNGDTPLLKAQSLARMTEVFEQNEAGALVLGVTVPDPSGYGRIIRAEDGSFENIVEDSDADEETKKIAEINSGMYVFNSHSLQTALTQLTPQGPKREYYLTDTLALIKQMNQPVVVFAGRDYQQALGINSKAQLAEAEQIMRDRVAAELMDEGVTLVRPREVYIDPGVKIGTDTRICPGCYICGNTVIGKNCEIEGNVYIKDSVIGDNVTLKMGTYIEESQVEACCQLGPYAHLRPKSVLKKGAKVGNFSEIKKSVIGEGSKVNHLSYIGDTQMGAGVNVGAGTITCNYDGKNKHQTLIGDHVFVGSNVNFVAPVTVHEYAKIGAGSTITKEVPAESLAIARSRQVVLEKKGVKKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9W2</accession>
    <name>A0A1Y4D9W2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56047">
        <property type="protein sequence ID" value="OUO56047"/>
        <property type="gene ID" value="B5F75_07170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="68" mass="8006" checksum="A663B4F7DA7A08A5" modified="2017-08-30" version="1">MQKLFSAFFKSKRVKKDLITPGLTKAQTEGELHFFNPARKERTVCVFRRKNCKNNQPATYLYNKKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9Y3</accession>
    <name>A0A1Y4D9Y3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="8" type="ORF">B5F75_07210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56054">
        <property type="protein sequence ID" value="OUO56054"/>
        <property type="gene ID" value="B5F75_07210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="7">
        <location>
            <begin position="13"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="159" mass="18081" checksum="ACC4C76AD57060EA" modified="2017-08-30" version="1">MPRKGLRPRDRRPQPAPDYKYNSVLVARFINKLNFEGKTSTAERILDDAMAIIAEKTKENALDVFTKCIENVRPLVEVKARRVGGANYQVPTEVKPLRSTSLAMRWLIGAAQSRKGRPMAEKLAEEIMLGAKKEGTAFKKREDVHKMAEANRAFAHFKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA62</accession>
    <name>A0A1Y4DA62_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56147">
        <property type="protein sequence ID" value="OUO56147"/>
        <property type="gene ID" value="B5F75_05875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="4"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="20011" checksum="440E4CC9A2F2C83E" modified="2017-08-30" version="1">MAKKVLIISASPRRGGNSDLLCDQFLKGASEAGHQVEKISLREHKINYCTGCGVCNNTHRCVQQDDMAALLDKMVQADVIVLATPVYFYSMDGQLKTFIDRTVPRYTEITDKDFYFILTSADTNKKNLARTVEALRGFTEDCLDNAREKGIIYGTGAWQKGEIKETPAFEEAYQAGKHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAM6</accession>
    <name>A0A1Y4DAM6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_06445</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56254">
        <property type="protein sequence ID" value="OUO56254"/>
        <property type="gene ID" value="B5F75_06445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="505" mass="55373" checksum="AE878959D767736C" modified="2017-08-30" version="1">MVHLFKPTSYTAGAALAVGATLAWKLVSFANALLIALYFGAGRTTDVYFYLLMVMGFGVTFLQRMNAAVIIPEAMAQEARAPGAGRPLLNSFLYFYILLLLLLGAAGFLAPVGLARLFSRFDAPQLLANQLLITLCFVLFGLQLLTAYLTAVLEMYRRFASALLTPLNALLPLVFLIACGRTAGIISMVYGFLTANLVQIAVFGWMMRKELKWNFRPARVQWQKHLTKNLASNQLIELANIVSSVLPLYLLSGLSAGLVSALNYARQLSDSPTEIFTFRVANVSKIQLTEDASARAEAKLNADFLSTQHFLLFVLTPLAVFTAFFAPEIVTLFFKRGNFSAADVQNAAAFLRPLMGVMWFLAIVSMQNNVVAAGRKVKESLPYALSCIGLFILLVPFTMNRWGAFAFPYTQVGCNVVSLWINYRLFKTHFPQIRYMQSLRDAGRVLAVNLLALLPAALCGFYLAGSGVLATLLASGIVFLAGVFFLSVKSGEWQAFAKHFAGSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAM9</accession>
    <name>A0A1Y4DAM9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56277">
        <property type="protein sequence ID" value="OUO56277"/>
        <property type="gene ID" value="B5F75_06580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012328002" description="Hydrolase_4 domain-containing protein" evidence="1">
        <location>
            <begin position="47"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="72"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="311" mass="33373" checksum="AEF1012878764065" modified="2017-08-30" version="1">MRKKKLRSGLNPKRFWTVNMFCRILKFAAPVWALALLALPAAGADAKEQAVSLSTQDGWALAALYRPADEGKRTVILLHDLGKNKEEFSTFKANLGSEGFGYLALDLRGHGQSTNKGEAFSFAREGVDNEYNKMTRDVEAAVSFLDKKGVSQQDMVVLGAGLGANVAAKSMSFSPDIGGVALISPTTNNRDVLSIPAMRLYKGDILIAAGAADKKSFLEASVIRNVAFLTAGEGKVTFLTAYDLTSHDMLDKYLRPAVIQWLKTPHKPEVLPDAPAVDLTVPTNTQGLLVPPSGTEESLVPSVLGVQQGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAQ7</accession>
    <name>A0A1Y4DAQ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycogen phosphorylase</fullName>
            <ecNumber evidence="4">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_06670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56293">
        <property type="protein sequence ID" value="OUO56293"/>
        <property type="gene ID" value="B5F75_06670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102250">
        <property type="term" value="F:linear malto-oligosaccharide phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102499">
        <property type="term" value="F:SHG alpha-glucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011834">
        <property type="entry name" value="Agluc_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024517">
        <property type="entry name" value="Glycogen_phosphorylase_DUF3417"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035090">
        <property type="entry name" value="Pyridoxal_P_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11897">
        <property type="entry name" value="DUF3417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02094">
        <property type="entry name" value="more_P_ylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00102">
        <property type="entry name" value="PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF3417" evidence="11">
        <location>
            <begin position="12"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF11897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="851" mass="97251" checksum="8523E245A9691348" modified="2017-08-30" version="1">MKIHSFNVQPNLPENIKFLEELANDMWFTWNWQAILLFVQVDPKLWTSAKRNPKWFLGCVPQKRFEELSKDEKFVHDLNQVKEAYYNYKNNQHTWYKEHRHENGNLLTAYFSMEYGIGEGLPIYSGGLGMLAGDHMKSASDLDMPIIGVGLFYKQGYVQQVLNREGWQNEEYPDNDWAHMPVERVTKDGKEITVDIPLGNETVKACIWRVPVGRTSLYLLDTNLQENTPAQRAITEKLYGGDRENRIRQEVVLGIGGVKALSAMGIRPTVYHINEGHSAFLLFQRIIDIMKEKNLSFAQAREIVWATSVFTTHTPVIAGNEHFDPALVRKYMDFYAREMGISWDEFLALGKEKADSATYCMTVVALRLSAFCNGVAKLHGKVSREMWHNLWPGLPVSEVPITSITNGIHSASWISHELNELYRKYLFNNNQRGEVDPSDEKIWAKISDIPDAELWNVHTIRKNKLIDMVRGRLKRQLTRQGFDVMSVKKASKVLRPDTLTIGFARRFATYKRATLLFKDLNRLDKIVNNPQRPVQFVFAGKAHPADTAGKEFIKMIVGLTQNDPRFKGKIVFVEDYNMNTARYMVQGVDVWLNNPIRPMEASGTSGMKAALNGALALSILDGWWDEVGPCDFGWSIGGAENYKSDAERDTVESEAMYNLIEQDIAPAYYAKENGSEYSLPWLSLMKESIKHIAPVFNTNRMVKEYYERFYVPANNYGLILNEPGKAEAVAAWRRRIAENWYRVSVTDITPQPETAILMGDKVHFKARVVLGALTPEEIQVELYLGQRGTLGDIVKEDAIDMTCTGKDGDAYLYEVSMSPLNSGRQDYALRILPFNNDIPNVLTPLFIRWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAU1</accession>
    <name>A0A1Y4DAU1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56176">
        <property type="protein sequence ID" value="OUO56176"/>
        <property type="gene ID" value="B5F75_06050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="227" mass="26241" checksum="65EA7F95BEA79900" modified="2017-08-30" version="1">MISFLIKHKKIILIITLAFFLGSIVYLGADAYRRGNFSNTAAQVGSADITYRDLYRVTEDRARVLRNQGVDVDENMMKFLQQQFLAALISEEVLNQAAHQAGLEVSDYEIAYDIQTSPFFSQNGQFNKTAYEYALKRSVGMTPAQFENQLRKGKLADRFRGVLYSYYKLTPEEIKYEYKKQHGNLKNFDENKNEFASQLMDTKMQTAQTGFFDQFNSEVEIKTFLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAU7</accession>
    <name>A0A1Y4DAU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">B5F75_06835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56324">
        <property type="protein sequence ID" value="OUO56324"/>
        <property type="gene ID" value="B5F75_06835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="20"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="292"/>
            <end position="295"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="37630" checksum="FED94130C6A42113" modified="2017-08-30" version="1">MVIDYLGGLFSSDLGMDLGTANCLIYVKDKGIVLREPSVVAVERETGEVKAVGAKAKQMLGRTPANIVAVRPMKNGVIADFEVTQEMIRYFIRKVHSRSSLLRPRIVIGIPSDITGVERRAVDDAARQAGAREVYLIEEPMASAMGADLPIAEPHASMIVDIGGGTTEVAVISLGGMVVAKSIDVAGDELTECIVQYFRKKYNLIIGETTAEEVKINLGSVYPLKEEKSMEVKGRDQTQGLPRTLTVTSEEIRQALMEPVRLIIDVIKSTLEETPPELAADLVDRGLVVAGGGSLLRGITELIRKETDIPVHRAADPLSCVALGTGKFLEQLNEKGSRFFGSRHKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB15</accession>
    <name>A0A1Y4DB15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56236">
        <property type="protein sequence ID" value="OUO56236"/>
        <property type="gene ID" value="B5F75_06355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010415">
        <property type="entry name" value="LpxI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043167">
        <property type="entry name" value="LpxI_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041255">
        <property type="entry name" value="LpxI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06230">
        <property type="entry name" value="LpxI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17930">
        <property type="entry name" value="LpxI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LpxI_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="LpxI_C" evidence="1">
        <location>
            <begin position="139"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="275" mass="29955" checksum="96B4AB50A4AFA6AF" modified="2017-08-30" version="1">MTTKKIGLIAGEGKMPVYIAQKATANGYEVYVAGAKGNAKEEDFKTCARVFRAFRLGQLGAGIRFFKEHGVTRVVMAGRVQHTSIFSNLMPDLRGAKFLASLKNMQAKNILSRVMDEFKKDGITFENSALFLEDFMPQKGLLSARPLTPEEEKTAAFGYKIAKAIAALDIGLTCVVSQNAVIAVEGMEGTDRCILRAGELYKSSAEKKSTVAVVKVARPDQDSRFDLPVIGKGTVESLHKAGFEVLAFEAGKTLVLDLEEVIRLADKYHISVTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB31</accession>
    <name>A0A1Y4DB31_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56256">
        <property type="protein sequence ID" value="OUO56256"/>
        <property type="gene ID" value="B5F75_06455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="13"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="177"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="360" mass="40868" checksum="68DE87E650C1B670" modified="2017-08-30" version="1">MRITCVIGTLGGGGAERVMTYLCGGLAARGHEVTLLTLDDSVPDFYSVPDGVRRVNISLPTFKKAGFWGGIPRLWKLTRAVRATRPEVVVSFMTVSVLAACWLLRIPYIYADHLDVRHLAYSLKWKILRNFLLGKAFRVTVLSERDRKFIALYHPRWKPAVIYNPALPPQKNFEPRPDFLQEGKKYVLAVGRLAKQKGFDRLLEAWRRICEDFPDWRLCIIGAGPEEAELKGLADTLDVQYCVQFVAPVKNLDAVYRHVDLYAMSSRAEGFPMVLLEAMSFGLPVVSFNCTGPDVIVRDGVDGFLVKQNYTDRLAAKMAELMKDEALRRQFGEKAREITKRFSLHKYLDAYETLCKEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBB3</accession>
    <name>A0A1Y4DBB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56145">
        <property type="protein sequence ID" value="OUO56145"/>
        <property type="gene ID" value="B5F75_05860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012395832" evidence="2">
        <location>
            <begin position="20"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="252" mass="28653" checksum="17A019C705FFEF87" modified="2017-08-30" version="1">MKKLFLLTLFCCVFSPLWANVSPKPEMEFSFVYQTANQPAIDPLHSEQIQCQDNQCLESKPLGVYGLQKLYCKKRSCFSIAYDYATYQQLIIAFEDGTKKQSNVFASPDTLRSHFNVYVTENDLKVEPSAAPTDRRSWARKDAWLSLGIVLVLELLAAAAYLFYREKSFTILYSVGLANLITTALSWMLLVRYVGDTAVLWVFCLIAEALIMRLMNPRKISFKDACMLSLTTNVTSYSIGMIISFLLAPYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBB6</accession>
    <name>A0A1Y4DBB6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_04495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56457">
        <property type="protein sequence ID" value="OUO56457"/>
        <property type="gene ID" value="B5F75_04495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="170" mass="19163" checksum="191F3D0A7B767274" modified="2017-08-30" version="1">MKNKHRLFIKIAELVAEQSTCCRLQVGAVLVKDNRVISMGFNGTPTGQLHCEENFKTIYEQSYRDKFPTYADFVASRTFYDLHGKWSVENELHAEQNAIAFAAKNGIATQGASVYVTWSPCVHCAKVIVSAGIKKVFYKNMYDRSQDGIIFLARNGIECRQLTEKDIAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBC9</accession>
    <name>A0A1Y4DBC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56484">
        <property type="protein sequence ID" value="OUO56484"/>
        <property type="gene ID" value="B5F75_04630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010987574" evidence="1">
        <location>
            <begin position="23"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="345" mass="37337" checksum="FC866530314DFB88" modified="2017-08-30" version="1">MKKTLFLLIAVLVTALNCPAQSKLQQALPLLQKNNRSAAENQQVLTLFRSAKDPDTVFAAGASLVKIPPSKIQEPVLFNLILKEDDPLKQTFAAIIVTAMGDGTEELLPLVQGALESKDPILQSYAAGAYGLLNPEDKAYTSQVVRLYAFDSAFALRAMNRLADNSKQLLKYLKQASSSADAATRAAAATWLGSLHSEDAAKQLLKMAKTETDSSVQTQIAIGLALNRSYTQEETAKGLRKNYTDPSSATYALALGFMTGNAAETIRQGLQSAHKNERINSARAAAYMAGVLSNPDAFNYTSDRAFDTGLLKSMIPQLKLLAKTGDDSVKIYAENALRQIEKLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBD6</accession>
    <name>A0A1Y4DBD6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_04545</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56467">
        <property type="protein sequence ID" value="OUO56467"/>
        <property type="gene ID" value="B5F75_04545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011815">
        <property type="entry name" value="PBP_1c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009647">
        <property type="entry name" value="PBP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06832">
        <property type="entry name" value="BiPBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02073">
        <property type="entry name" value="PBP_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transgly" evidence="9">
        <location>
            <begin position="46"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="8">
        <location>
            <begin position="291"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="BiPBP_C" evidence="10">
        <location>
            <begin position="613"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="701" mass="77366" checksum="D78F9C3F4BDBFF83" modified="2017-08-30" version="1">MRCIWKVFFLLLLPCLVWGEEAFLSPSKQIYDRYGAPMRGFLSENNTYYLPVPLTEISPWLIAAALAAEDKRFFSHPGVDVKAILRAAWQNATEGEIVSGASTITQQLARALEPRPRTLWGKAKEAYNALLLEREMTKEEILEEYFNLLELGNLTQGAEAASRFYFNVSASELSLSQAAFLAGLIKSPTYYNPLKHFSRAIKRRDWVLKRMLENEFIDEEMYQMAVAEKLELKSASRPFDAPHFTRFLYPLLPPQTQDVYATIDRDLQLYAEELVKNYISQLKEDNVTNAAVVVVENATGGVLAYVGSADFYDQAHNGQVDGARALRQPGSALKPFVYGLTFEQGLLTPASLLDDKDTFFEGGFRPRNYDESYHGFVPVRTALACSYNIPAVRAAEKTGASNILALLRRAGLTSLEKPADFYGLGIALGNGEVRLLDLTNAYAALARGGVYKPLRVGQRPAIYLPGRETRIFDEQTAYLVTDILADNNARAPAFGLNSALSVPFALAAKTGTSKDYKDNFTLAYTPRWTIGVWVGNFDATPMQKVSGVTGAGPIMHDLAVYLQKKYPSEPFETPAGITRALVCTQSGLLAGPACTHTKEEVFSSRHLPAVCSGRHQVAVSALAITSPDKGDVFKMDPSIPRAAQVLRLEAACAEKSCRWTMDGEKLPGISCQTWWPLKPGKHTLKVSCASEEASADFEVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP3</accession>
    <name>A0A1Y4DBP3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gatA</name>
        <name evidence="9" type="ORF">B5F75_06620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56285">
        <property type="protein sequence ID" value="OUO56285"/>
        <property type="gene ID" value="B5F75_06620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="20"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="471" mass="49968" checksum="A65E5698BD42F8D5" modified="2017-08-30" version="1">MMTALEIVKAVSAGEKTAEEITRQALAAIAQKNPDVNAFVEVFEQDALARAKEIDAKRARGEKLGALAGVPVGIKDNILYKGHKATCCSKMLENYVASYTSTVVERLLAADAVIIGRTNMDEFAMGSTNQTSVYGPVKNPANLECVPGGSSGGSAAAVAAGMVPVALGTDTGGSVRQPAGFCGVVGIKPGYGRISRYGIIAFASSADQVGILSSTVADAAKVLEIISGKDVHDSTSLEAPVPQYDAQFTNGLKGMKVGLPKGFLDGLGQDIKEKVTQAAARLKDLGAELVEVEVPLAKYAAPCYYIITSAEASSNLGRYDGIRYGYADNAAKDLNTYYEGSRAPFGLEVKKRLIIGTYALTSERYEECFLKAMKVRELIREDFKKAFEKVDVLLTPTSPTTAFKLGQHDEDPLALYLADLYTCQGNIGGLAGISVPFGKDAKGLPIGVQFYGPILKEEKILNAAYNLEKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC61</accession>
    <name>A0A1Y4DC61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56646">
        <property type="protein sequence ID" value="OUO56646"/>
        <property type="gene ID" value="B5F75_05500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="26470" checksum="4BADA900397D0EE4" modified="2017-08-30" version="1">MIKRPFIFLTQDYGKMISNGSGTDLSGQLSNINIQSFPYELTFFFTDRWGNITNRKVDTLILQDTTLVNATISAADSTGNYNTLFTVSGNTDNTFMLKAQQAVTTSSLKISITADGNPGTVTVGRLMLFGYICDLFALTDATFKKDTNQGSYRLVSGDIVYYGDYDKLRTKLKTENLPEAQFKDITAAVDESNQLTMLPFYDDEIGGIYECYADPEYSFSLDRKTGLYALDLELEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC67</accession>
    <name>A0A1Y4DC67_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56455">
        <property type="protein sequence ID" value="OUO56455"/>
        <property type="gene ID" value="B5F75_04485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012847892" evidence="1">
        <location>
            <begin position="20"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="297" mass="33329" checksum="1F263CB591B21B1A" modified="2017-08-30" version="1">MKKLFILLFACLCAIPAAAQSGKIIKPALKAAAGKTIPSAAPEISLQQAQAAYLQAARNYNRFTPPLVSSDYVLAQGKKLQLQSGALHRQLARWMNQRIRSLEELKAKKEEALLIYGQALAQNHGWTDTVRNMPSPLPDMFPRYIEGTPMELPFEKYVRALTAKTGNVKALGTLQTEQQAIAAFLQKDLKETSQELFSRVSDPDPLGEIIPLSFATANRLVQLTQFMLRHPNAFQPQLFELNVRVAQAPKTPFNDYLCTLLQKDPNYPTYYAWLRAEKTGINFTPFQRMYNILSGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCE9</accession>
    <name>A0A1Y4DCE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="4 7">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">B5F75_03030</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="4 7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56834">
        <property type="protein sequence ID" value="OUO56834"/>
        <property type="gene ID" value="B5F75_03030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PTHR22931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="41"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="469"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="566"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="882"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="668"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="796"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="817"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="818"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="819"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="931" mass="102002" checksum="FA15840D269B0918" modified="2017-08-30" version="1">MVKKTVKKAAKTAAKKAVKKAVKYVYSFGAGKAEGNGKMKELLGGKGANLAEMAGQLKLPVPPGFTITTEVCTYYWNNKRTYPKTLKADVEANLKKIERETKKQFGSEKNPLLVSVRSGARASMPGMMETILNIGLTEKTIPGMIAKTGDARFVYDAYRRLIMMYSDVVMEKAAGIEPKDGEGIRKILDGMLEELKNKLGVSDDTHIPAEELQKLCVQFKATVKKVLKKDFPDDPMEQLWGAIGAVFASWNGKRAIAYRNIENIPHDWGTAVNVQTMVFGNMGDTSATGVAFTRNPGTGDSHFYGEYLINAQGEDVVAGIRTPSPMNKWSANAHSKHLPTLEKVMPKVYKELDAIQKKLEKHFHDMLDIEFTIEDQKLWMLQCRVGKRNGTAAVQMALDMVKERLISKEEAVLRVTPTQLGELLLPAIDPKAEAGVKPIAQGLPAGPGGAAGKIVFNSLDAIKLQEAGQNAILVREETNPEDIEGMRAAAGILTQRGGMTSHAALVARGWGKCCIVGCGELEINLNAKTVKMGGKTFKEGDELTLNGTKGYVYEGALKMLAAGEGNKNLAAFLALCDKVRTMKVRANADTEEDAIKARKFGAEGIGLFRIEHMFYGKNSDKPLFILRKMILSGSEEERKAAVEELFPYMKKEIKATMKAMAGFGVTVRLMDPPLHEFVPTLPEKQAELAKALGITMDVFKDRAASLHEVNPMMGHRGIRLGVTYPEITTMQSRAIFESAAELIKEGVKAQPEVMIPLTCDVNEIISQKKLIRAAYDEVVAKTKVKKLNFSVGTMIEIPRAAVLAYEVAQETDFFSFGTNDLTQMTFGFSRDDIGSFLPEYLKQGILEADPFQTLDQRGVGMLIEHAVAEGRDAKPNLKVGICGEHGGDPESVEFCHREGFTYVSCSAFRVPIARLAAAQAAAKDVLAKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCF8</accession>
    <name>A0A1Y4DCF8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tyrS</name>
        <name evidence="10" type="ORF">B5F75_03080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56844">
        <property type="protein sequence ID" value="OUO56844"/>
        <property type="gene ID" value="B5F75_03080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02007">
        <property type="entry name" value="Tyr_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="226"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="386" mass="42406" checksum="1AD62229A5623A34" modified="2017-08-30" version="1">MTVEEQINFLTRGCVDVVTKADLAKKLESGKTLKVKLGCDPTSADLHLGHSVALSLLRRFQDLGHKAVLVIGDFTAAVGDPSGRDSTRPVLPREKILENAKTYTEQAFKVLDPSKTEIRFNSEWLEPFVSGKELMQTLQKVTVAQVLERDDFKKRMAAGNPISMLEVLYSLFQGQDSVALEADVELGGTDQIFNLLVGRQLQKNHGQEPQVAITVPLLVGLDGVKKMSKSYGNYVGLNDEPGDMFGKLMSIPDELMPMYYELLTSENMQDIKAMHPMAAKKKLAGLLVTRFHGEEAARAALENFEKVFSKKELPTDMPEFKPEAGAMLSAVIFAAGAAQSKNKARGLIEQGAVRLKGEKVSADGPLSFEPGDVLQVGKRHFFKLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK1</accession>
    <name>A0A1Y4DCK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmF</name>
        <name evidence="6" type="ORF">B5F75_03300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56884">
        <property type="protein sequence ID" value="OUO56884"/>
        <property type="gene ID" value="B5F75_03300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="69" mass="7829" checksum="95B3D924E42643E4" modified="2017-08-30" version="1">MPNPKKKHTRSRRDMRRSHNSGVELPQLVACPNCKSPRLPHNVCPTCGFYKDRVVVAQKTKAEATEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU0</accession>
    <name>A0A1Y4DCU0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56984">
        <property type="protein sequence ID" value="OUO56984"/>
        <property type="gene ID" value="B5F75_03815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="480"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="556"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="590"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="694"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="876" mass="98883" checksum="AF7FD11EF424877A" modified="2017-08-30" version="1">MLNLTKSAKETVYMKIVRVLLAMCFLVVPLVFFTDLTANPFFVQNTLLYLLIALIYGTLAVKFLRSKDIDFTKTFFDLAFFVYVTACVMGWLSAVSSAQQAMRQTLFYDLLNYGSLLIIVSLGAYIISKNIVFSGTIESKTNYILLFLGWGALWYFLPMLKTHLTSENILAQLFDWYALLLWGVGVWLGMRVLRKLTQENILVLMFIAVFLACCYGVLQALGLEFLWPFEINQFASKAFSTFGNPNFLSSAVVMLLPALLVYFMRTDSKKDFVVYGLLVLVYILFLCFGLARSCWIGAAVALVMMWMFGTLRALIWKRKGRVFLLALLAVGVGWGSVYVDGTDMPSPVAKRAAELAQVTPSNITLKVDRDKIFQSLHQRLFMWDVSKEIFLERPVLGSGLGNFQMAFEQNQPKTLLRYPNLRELKTITHAPHNELFFQLGQGGIVGLGLFLFMFMVLFLEMRDFAAHKKEGDKKQLLQALFCGILGMLADNMLNISLHAVVPAFIFWWMVGAEVSGVGKEERRISITANPVTKTVALAVLGASAAVLVWQGLWLTSEYHSFLGQKDVAVKKYDSAVKNLSEALALYPANTEAGFRLGNVLLAQGKYKEALEAFEKTMSAASYYEEVYFHAALAALGANEPKKAVHYLMDNLRLHPYNLQAYLMLSQLLHEDVIYADASALALMERGLTLFPYETNLWRLAGEIYQKLGDTEYAKNTYKRGLTVDTLDHELLQRLSALYPARSTDRPAVIAQAQRLQRYQDKANKFNKMSPYYQQRLRKDIEAYIKDYPDDTNGPILLARVLSLAGNDIKAEEVLEGVLEKYPDDLWANLALSTLYYKAEDVKKAEKCLQDALFYYPQNALATARLKALEQAGLIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU9</accession>
    <name>A0A1Y4DCU9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56937">
        <property type="protein sequence ID" value="OUO56937"/>
        <property type="gene ID" value="B5F75_03580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="23237" checksum="4F333E3FFD6A7929" modified="2017-08-30" version="1">MERLLQMLGVLAALYAAYALSIKKWDYETEAQRTARRTFLKSKGLSNTFYFIHAGTLFLLNLLSGGLFAFYWLYRQWQAVLHGFRRLSAKPLKHGPFLRAVGGFGTFFSLNAIICRTCEYMHHKAPLPPWVWGTAWLAGLAGTLAGTDVTTRAAGYLVFCAAPALLQRRLNALPKETIPPQPKPAEIAAAALALLLALGLLVAWRIFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCY3</accession>
    <name>A0A1Y4DCY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Anion permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56472">
        <property type="protein sequence ID" value="OUO56472"/>
        <property type="gene ID" value="B5F75_04570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="349" mass="37287" checksum="A6C4999E11157E88" modified="2017-08-30" version="1">MLWILFLIILALFFDYLNGFHDAANSVATVVSTRVLSPKVAVAWAAFFNFVAFLIFHTGVAKTIGAGIVDIHIVDSNLVFGALMGACVWNILTWWWGLPSSSSHALIGGLIGAGFVKGGVDALMAGGIFKTVLFIFLSPLLGFLLSVIIGIIVFNVCRPFNPYKVDHWFRKGQLLSAAAYSLGHGGNDAQKTMGIISMLLLGGLAGNEVAPIRDFLLTHEEMHAVTQGAFIVPLSVVLLCHGAIALGTLSGGWRIVKTMGQKITRLRPVDGFCAESGSAISLFIASVLGVPVSTTHTITGAIVGVGSLRRLSCVRWGVANRIVWAWFITIPAAALISAASYWLKTCLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCY9</accession>
    <name>A0A1Y4DCY9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase_S8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56886">
        <property type="protein sequence ID" value="OUO56886"/>
        <property type="gene ID" value="B5F75_03315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012305662" description="Peptidase_S8 domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="68"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="335" mass="35026" checksum="24BB0A85AD39219D" modified="2017-08-30" version="1">MIRKSVWLGLCLCVGSCVYGADTVFLGPTNLRVSDQGEFSWVDTTPKPQAFDNLWAYRYYPIEKKLTGMGVKVAVADSGISSHPEFNGKHIMGQDFTMSGALTDLKNHGTGVAGIIGARGLRFTGIAPEASLLIYKIDDGSRLIGPQAAANALNTILTYNEQNPNDKITVINLSYGVSGGGYAALTNAVNRAHDSGITIVSPAGNYGFPGVFYPANLSTVIAVSALGADGKTLYPNSAYGPEVDFIAPGDRVFTASSDGGYTLMSGTSAAAGFVSAAAALAVEGLTRQLGRYPTAQEVKDALKKAAVKIPGLPDIAQGNGMIDVAKLESQFEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD04</accession>
    <name>A0A1Y4DD04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57003">
        <property type="protein sequence ID" value="OUO57003"/>
        <property type="gene ID" value="B5F75_03920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="384" mass="43394" checksum="D4F812A8552EFDAB" modified="2017-08-30" version="1">MEHKMNILPKTLKHTFLLAGAVAFFALPSYGQLPEKILPAAKTALQPAFKVPLAQKIAVPGGLRQNFGPAVSVYTARPIPTPEPPIIPKVFIARFYPLTDSQTTLVQGLLRKKLAKPAPTFYEMFKQAVYLHQKNPSAFKKVSQRYYYEMTLFLKHAAHVTQQAGYPAVAAYLKEHKGDFPTLHSGGTLSANDRSARMLTFYASEEMNTLMNQILSRPAEKQIITDDEWVAINVLSTFFPAQTRPAFYNFLLDKQYKELQILSLDPYMHNSDTRRLVQGTIDPQSVHAPSLAKRISSRERYLQYLTQRKAALPGTISHKRQQYAKNQVIYDILSAEGETAPSAIQAKNALDKSYREYTQASLQLKEISAKIEQVTDELNFLRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD13</accession>
    <name>A0A1Y4DD13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56916">
        <property type="protein sequence ID" value="OUO56916"/>
        <property type="gene ID" value="B5F75_03470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="91" mass="10841" checksum="CFC299BBB6BA5429" modified="2017-08-30" version="1">MQTLLAYLKKPYAEKGFIVGTFDLLLKLLTVFLWGYIAVILCTLFVDSIVLDYNPLNKLWWFSYCFLIFFGATWLAYIVLFVRDYYEPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD41</accession>
    <name>A0A1Y4DD41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DJ-1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56542">
        <property type="protein sequence ID" value="OUO56542"/>
        <property type="gene ID" value="B5F75_04940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="2"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="181" mass="19462" checksum="2BFDE1B043C0E56A" modified="2017-08-30" version="1">MKKICMIVTDGFEEIEAVGTFAILRRGGVTVDIYSLLDKDATGRFGLTCTKLLPFSKLDAAQYDLLVIPGGAQYKALEASPEVHALIKQFMDAGKTVAAICAGPTILGHDGYLKGRRYTCFTSMNEDFGGTYCEDYAVKDGNIISGKSAAATIDFAFLVLEDAAGKTVADQTKKAIYYKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD42</accession>
    <name>A0A1Y4DD42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ETF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56997">
        <property type="protein sequence ID" value="OUO56997"/>
        <property type="gene ID" value="B5F75_03880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="265" mass="28435" checksum="F3EA046F2F96A9EC" modified="2017-08-30" version="1">MHIVACVKQTPKSDNVKIDPATGCLIRSGAASAMNPFDEYALEEAVTLKEQQGGTVSVITMGPPQAEAVLRDSIARGADSVYQLGDVAFAGSDTWSTSYALSKGIEKINAIRPVDLIICGKQTNDSDTGHIGPQISAWLKMPNAAFVKKVVEVKEKSIVVERLTEDGSEVLELPFPCVLSVVKEINSPRVRSVKGRMAAKRAQVTKWTADDIGADKNMLGVKNCPTHVVKSFVPKREVCAVAVEGANGKEKAARLVSLLKEGKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD49</accession>
    <name>A0A1Y4DD49_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56795">
        <property type="protein sequence ID" value="OUO56795"/>
        <property type="gene ID" value="B5F75_02825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="409"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="29"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="494" mass="53938" checksum="92A4A409212564BA" modified="2017-08-30" version="1">METFGYSRRFNVSTYMKIQAPHIAYKWLIFSVTAIGVFMSTLDGGIVNIALPVMAHDLNAGLERIQWVVSIYLLTTTCFLPVFGKLSDMYSRKYLYLTGFLLFGVGSLLAAFSKSLSWMIFSRIVQGLGASAMISNCQAIIAKAFRGKDRGRALGGIGAMVAVGFLAGPAVGGFLIQHWGWQSVFWINVPISALGIWRGIQIIPLFKSNAKVKMDVLGAICFILFCFCFLYALDEGESQHWTSFLIIGSFVMSVLFFGIFYMRERTSKNPFIGLSLFKIQAISYGCIVSLLGFIALNCNSILFPFYMSDILHRSPLQMSLLMMPFPVALAIASPVSGWLSERYSARLITTVGFGFIIIGASMFVGIGTHPSIAYIIVAQLMMGTGSGTFQAPNNNTIIGGAPSDRLGMVVSISALARNMGAVMGIALSVLIFSSVKRHYLAAGLAGQDAFMNAYQASMVFCIVMALAAAYFSAAREKRKKRKKQPTGFYESTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDC9</accession>
    <name>A0A1Y4DDC9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57036">
        <property type="protein sequence ID" value="OUO57036"/>
        <property type="gene ID" value="B5F75_04100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="466" mass="53320" checksum="512D0A7C5B9F98CF" modified="2017-08-30" version="1">MRIQKKFLFIFITVGLFGAGTSFAQKQLLPAVRAGAVKQPLQVQKNLIKGVSVPYSEHLKDACLSWQPSVKMPQRFMASPKESALWRRLKQQVLLKRVDLHRPVTAWRKHLAAGGTGTGHLQTLGEFQETLQEIDNVGLGDRRFQKMLKYMQGIMPMREYSSVAVANNRLLLNYLQRLYQKFTWMDRYPNQGRQALKTVTSGNLARQLAARLQQEKLILLGETHFRFEVQQAVGDLIVQLKKQNPARRIVVFSEFLALPSQGKQIANQTLETYYRRIDAHTAPQLSKQAAAKQPYARGVFQRLLQARVEVYPLEDRDFSDLLKASGGQEAQALGVSYRNKTWARIIRQKMDEIRRTDPDALFIVYAGTGHTSWRRQSPLPAFFAPEKPVVVEFQFDLAFKNNVLYALWGADSAPFSNPQQASLSYWEGADAKQLVQNSGFDYLWVLPASFRGKLLRQYLAWAERMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDP1</accession>
    <name>A0A1Y4DDP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57233">
        <property type="protein sequence ID" value="OUO57233"/>
        <property type="gene ID" value="B5F75_00175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="141" mass="16618" checksum="935490005E0991E3" modified="2017-08-30" version="1">MPVHWGTCWERIKHFFDFAARRRERYLKWDQEAQNGDEEARYRLLMLYREEGEEYYPLAFKWTVIVANAGEDCGVMLQAAEMYLAGHGAPQNEEKALLWFERALSLHIMQGRNSPLSLDAANFIQEKIQELRAKLGKEHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDP6</accession>
    <name>A0A1Y4DDP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2157 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57244">
        <property type="protein sequence ID" value="OUO57244"/>
        <property type="gene ID" value="B5F75_00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018677">
        <property type="entry name" value="DUF2157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09925">
        <property type="entry name" value="DUF2157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2157" evidence="2">
        <location>
            <begin position="30"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="285" mass="30937" checksum="B932A5D090446843" modified="2017-08-30" version="1">MTKKQGALNALSTDLVAVVPAWVGPLCGLTGAALFLAGTVCFVAYNWAAWGVLSKFALPLVGLLVCAAGAYFAGLQHNAGKVLSFACGLFVGLFWVVYGQVYQTGAFVYEFCLAWAVSLLPLAVLAGNRWLWLLWAAACNGYILSRWSLWMTSEYMWILILFNTLCFAASEWAARRRGESGWFSLFFLAAALWFSLLDGLGSGWMLHFWSSLGLMALLGLYAWRFGRGAAQLGFCALALDVLLAEEVISSLNLGDGILTVLVVMALFIGSGWAVYALTRGEVRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDR5</accession>
    <name>A0A1Y4DDR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02760</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56782">
        <property type="protein sequence ID" value="OUO56782"/>
        <property type="gene ID" value="B5F75_02760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="480"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="517"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="544"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="746"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="17"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="311"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="772" mass="85483" checksum="3F8B0C2B0B588C44" modified="2017-08-30" version="1">MTENPSSSLVGKEISGCEILNKVAEGGMGAVYKARHKALNRIVCVKILSPALANDKKAVELFLTEARAIAELDHPNIVNVYNVGKEKGYYFIVMSFIEGQTLSMLLKRNKVLPIGLVLDLFEGVLLGLDAAHAKGIIHRDIKPSNILINPQGQPKLVDFGIAKKVDKEKGSTKTTELAGTAYFIAPEQALGKDLDTRADLYSVGASLYYVLTGQFPYNGKNTIDIIQKHINDPVPDPAKLRPDMPGWLSLAVQKLMSKNPDDRFQTAKETYLYFKKMRAEDQLRVRMGNSGRAIDLGEEGPLRIVKEEKRTTETIRRQRAEQAAVRKPTTSSAHLPLIPQVDASAPNEPAEKRKPASQPTIRMMEAKDVKPVDVFVPAAKKADKPILTDKFGLGARVLAKMAIFLPLFMVLAGAVMYVFYLLGKICSVHIDEQAGLVSNLIMPFFASTYEPNQLLMTGIALGLLVVVFASSSIRAFSRSTTLLLVLALVSYMAGLFTPQVPFMELANVSQFIFTPEYYLCYLVFVAAWAVSLCWTINRSLGQRILAASLSVLAIVLAYLSSHLSIAPDTQSLVVKIVFYAGLFCAVLCVYHLAARSEKDRILLPCFLLLFAGAAIWAYSVSGLAGNINKSLDVLTANIVVKETDVVKSNQKVEDLVGIDTRRQVFASLNKTNELTNMPDDQAYEFLSKKINQEAPNVFDENTKPLFIYFLLNYYRGGESKMKFTVWDYAMSFPVKNFNVNAQHNNAYFFLLAMLYVFGIISCAGTIFFSEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT7</accession>
    <name>A0A1Y4DDT7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57035">
        <property type="protein sequence ID" value="OUO57035"/>
        <property type="gene ID" value="B5F75_04095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012711900" evidence="1">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="447" mass="50852" checksum="ECD5B588CAB12FE2" modified="2017-08-30" version="1">MKKRIVFVLLLLGCGMLAAPSLWAQKRLLPIARAVKGDAVKNAVGGQTGKTGTSGFRSALGKELEEVADAAAAEEAFLANVSLKNIRVQQEEMEDLLSQLLELYYQANVSSEWAKRNREVVTEVKKLWLWNNQFLNNWLFKSIYKPIEWPSEFAVKNNKIVLLASRNFFGKMQWLANVPDQGRKLLGRLQSDNVLGEFAQKLNKERMILIGEQHGISSVQQTITKLVLFLKKQNPRRRVILFTEFIDLNSNAPREGSSLSDYYLKTKEMSLDKLNQEDFSSAARIDYAANLFLRLFQEKVEIYPLEDRRLMEVLEQECGPICQVKNPALSISLRNKTWARIIERKMAAVRQTDPNALFVVYAGIGHTSWLLPYSLPKFFAAEKPAVVEVTLGQPSSVSALYTVWGKEDVFFTPHSDLTLYYWKSGLGRIFAQKTGFDYALVVPEENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDV2</accession>
    <name>A0A1Y4DDV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH merR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57277">
        <property type="protein sequence ID" value="OUO57277"/>
        <property type="gene ID" value="B5F75_00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="113" mass="13319" checksum="DA2EB94DFCD38DC8" modified="2017-08-30" version="1">MGLEEIEEKDYFSIGDVKRITGVPEYSIRYWEAEFGLIRPIRLESGHRRYTKEDVYTILKIKDLIYKHKLTLEGAKKQLSKYQFPAAGRGEKPRTDIKLLTEIKETLEDLLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDV6</accession>
    <name>A0A1Y4DDV6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57055">
        <property type="protein sequence ID" value="OUO57055"/>
        <property type="gene ID" value="B5F75_04195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="370" mass="42363" checksum="6961CD3D44736972" modified="2017-08-30" version="1">MHFIRHAVWKLQDRKAQILLPSVLLAPIFILVIYLLFETAKVSMTKVRQQFALDNAAYSQVSSASTYLNAVAMVNGPLPYRVMLYYKDQKLNPKETAAQAGKQPISIFELFYHGGGVPTIAPNYDTGINNPPPAEKDDWGVRYDPAIQDFPRTDWEREDPREPDSNTWVPVVSRSLVNDYYFPALRYATVVIQNYLETYVQVGSIYESQSYVYKEVSKNAVMFREAYYLNTNDCKKSDCARQSASQLRRYITLSTKPFELDKVRFYASDSGLSGEHGGAINLDLPMSEIIKTKLFQFAYLDSSSRSKLRTLGRGVVLKQPFKLPRNHFNINLEQKYKPYVRNTVVLSCPRNSNNCVWPDPLPKYTVTLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW0</accession>
    <name>A0A1Y4DDW0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57226">
        <property type="protein sequence ID" value="OUO57226"/>
        <property type="gene ID" value="B5F75_00135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="108" mass="12139" checksum="FD05C50B2AD45DCD" modified="2017-08-30" version="1">MDSKLTVTDASFETAFKKYEKAEMIEFFASWCQHCKQMAGLVNTLAKAYANRAAVLAVDVETSPRTARRFGVQGVPAFVFVKNGQIVKRMAGEFSEEELRRQLDALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW7</accession>
    <name>A0A1Y4DDW7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase H type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57314">
        <property type="protein sequence ID" value="OUO57314"/>
        <property type="gene ID" value="B5F75_00620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13456">
        <property type="entry name" value="RVT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="194" mass="20987" checksum="EA59CE60CD10C215" modified="2017-08-30" version="1">MQVKINIDGGSRGNPGPGAAAYVICSPDGTILAQEGHFMPHCTNNQAEYTALKLALIKAKELGATELFIQSDSLLLVKQFLGEYKIKHPDLAARMAVIRRLAAPLTIHMQHVLRHLNKAPDALANKAMDAKQSVGFNPIVHLPPEEETLPPAAPENIVNGVEVKPVQRPKPAPAKSASKRALKKPHQPDLFGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE05</accession>
    <name>A0A1Y4DE05_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56882">
        <property type="protein sequence ID" value="OUO56882"/>
        <property type="gene ID" value="B5F75_03290"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="247" mass="25899" checksum="C40466E5F702665C" modified="2017-08-30" version="1">MADFKGKTVLVTGATRGIGLAIAEEFAKAGANLAICGTHPDALAPAAKTLSAHGVKVYTQPVNVAHAQDCEQFVQNTLKELGSVDVLVNNAGITKDNLTVRMSEEDWDDVIAVNLKGTFLMSKAALKVMFKKRSGNIVNISSVVGEMGNAGQANYVASKAGIIGLTKTFAKEFGSRGVRVNAVAPGFVQTAMTDALPEDVKAKALEAVPLKRFATTQDIAKAVMFLASEDASYITGHILAVNGGLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE25</accession>
    <name>A0A1Y4DE25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57373">
        <property type="protein sequence ID" value="OUO57373"/>
        <property type="gene ID" value="B5F75_00960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169749" evidence="3">
        <location>
            <begin position="21"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="214" mass="23667" checksum="56457F4AF9E51635" modified="2017-08-30" version="1">MKTFLLIGLFLLLSVSSGQAKEVDEFFAAVRNGNSQRVEEMLSKNKILVFTADKRGMTPFLVAVETRNLKMVSLLADSFSRLGNIAQPGNALHIAVSNDDEPMVRLLVRLTSEEDPALTKRLLNMRRRGDKEEINDRNTPLHLAALKCNFRVYNYLLEHGANPTLPNSKGKTPKQIISACPKPKPAKKQAAKPASSVPASKPKPVEEPLIFPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE55</accession>
    <name>A0A1Y4DE55_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57377">
        <property type="protein sequence ID" value="OUO57377"/>
        <property type="gene ID" value="B5F75_00980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="199" mass="21854" checksum="234DBEDF7D443061" modified="2017-08-30" version="1">MEEAIKRAQKIKAILTDVDGILTDGKVNFFVRDDGKIDEFKSFHTQDGIAVLLCHSAHIVCGIITGRRHPTTVARAKNLGFKYMYQGFLTKIGPLNDILEKENLTAEEVAYIGDDITDIPLLAEVGFAATVPNALDCVKKHAHYITKRVGGDGAYREIIDFILNAQGKLAPILEQVEASAWTSGKRPEMEVITSQEGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE59</accession>
    <name>A0A1Y4DE59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine transaminase</fullName>
            <ecNumber evidence="6">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphohydroxythreonine aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_03605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56942">
        <property type="protein sequence ID" value="OUO56942"/>
        <property type="gene ID" value="B5F75_03605"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="Aminotran_5" evidence="9">
        <location>
            <begin position="61"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="44921" checksum="70A65FA8A8D08CF8" modified="2017-08-30" version="1">MEGTKYYNRRKRRKIMSIQLDISKMPSATFTCGPSQGHPVIRQTPVYKTLFERSHRAKDISTEGLYKEAVDNLRQLLSLPPDYTVIFFLGGATPAMDAVIWSLTKNSLSGLSFGAFSKLWAEKIASRLEGKVIRSIRKAGENEFFPSEKPDYQASLVILTPNETSTGTQIPNEYLEEAWKLKGPDTLIAWDCTSCAGGRELPKNKFDVMLFSMQKCFGVGGGSSVIIMSPAAVKRLEEAKKYRTIPYALDLSEAVAKAQAKCQTVNTPSTTNIWMFNEACKWMNENGGLAAMDALCRQHAKYLLEWAAKTDYLKPLISDEAHRSYTTLTLEVTDPALKDADISAALKATGLPNLADGIKKYSSVKQNSLRIACFPFVDIHGTAEYEKLTAAVDEIVRQLRQEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE87</accession>
    <name>A0A1Y4DE87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57443">
        <property type="protein sequence ID" value="OUO57443"/>
        <property type="gene ID" value="B5F75_01335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025294">
        <property type="entry name" value="DUF4156"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13698">
        <property type="entry name" value="DUF4156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011011941" evidence="1">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="131" mass="14210" checksum="98FDDF021B20F91D" modified="2017-08-30" version="1">MNKHKLWILLAALCGVSGCAVWQQAQGPVVPANGMDVDGVTLVEVQPAAACVFKGAVMGDTNPDVSGIPESLLHLNNTIRQGLVSSAKQMGGNTVWVRTQSWQNPDMDTDYFQPFYINNVRYGALVYQCPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE97</accession>
    <name>A0A1Y4DE97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57454">
        <property type="protein sequence ID" value="OUO57454"/>
        <property type="gene ID" value="B5F75_01390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="159" mass="17911" checksum="D281B6BE696DE89C" modified="2017-08-30" version="1">MLKIFIKAAILVFIILSIYFIVNPSACSNLMMGRVTNSMDETPVVNSQPADHSEMFVPSGDQPLAAPQEGVFDTNTMNEPEIPTYSQEDIDYAVASRYVELENEYAKKGALGKDTAKEISYIVMDDFELTQQEWESFLQRATESNLFNKIRSEQLPVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE99</accession>
    <name>A0A1Y4DE99_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56029">
        <property type="protein sequence ID" value="OUO56029"/>
        <property type="gene ID" value="B5F75_07045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010996149" evidence="1">
        <location>
            <begin position="20"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="372" mass="42606" checksum="28E3C420270FE962" modified="2017-08-30" version="1">MRKWRLLFFFLSVASAVSAQPGGPAWGKQLVRVLGPTAARQTAVVPAPKLERALQTQLLAHTRWKNALPLKADLYLPARSMAVKSSPSILPASEADAYFNYINDQLAAVWQSVTERDIALLQHYKTDILKSLHVRLPRQPVQYAALIPPQAKYIAVGEEHGFAPLRKAFEELVLGYRHMYPERKIIVLTEFVFDRTLPLSEKTGEPVSLLGLKYRRVSADFRFLEKFVKRGIDVIGLEDERYFRSHQRLITPVFRQVESVYGMKQRNEHWREIIEQVRRREPEAVFFVYTGNMHVHYRAPYSLARASSQVFVLQFFAGELGRDLPFGAVMQKEPFARTEGDARYPTVLSWPQASPYRMLSGFDAGLIFPVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA2</accession>
    <name>A0A1Y4DEA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD(P)H-dependent oxidoreductase subunit E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57464">
        <property type="protein sequence ID" value="OUO57464"/>
        <property type="gene ID" value="B5F75_01440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="161" mass="17633" checksum="DAAD1534FAEA8B32" modified="2017-08-30" version="1">MTDKFAPAAKILKDHNYDSSKLIPILQKVQDEYKYLPEDIMRFIANELDISPAKVFGVATFFAHFAITPKGKHIIKVCNGTACHVKGSSFVINTVKDKLKLKDGQDTTEDMMFTLECVSCLGACGLAPVMVMDDVVHGQITPAKAVEIIDEVIASEAKNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA4</accession>
    <name>A0A1Y4DEA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">B5F75_07100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56039">
        <property type="protein sequence ID" value="OUO56039"/>
        <property type="gene ID" value="B5F75_07100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="18070" checksum="86FB7965C22B7AFD" modified="2017-08-30" version="1">MGEKTYGENQMIAHIFYKTDVPKYLRRTGLFKAALQKGLKHFARQNIEVNVIFVDEKEIRRVNVEFLDHHYVTDVISFNNEKPPFDTGEPWGFGDIFVCYPVARKNAKLFGHTILQEMLMYVTHGALHLSGMDDHDPKDRAEMDRQAEKIIASVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB2</accession>
    <name>A0A1Y4DEB2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57484">
        <property type="protein sequence ID" value="OUO57484"/>
        <property type="gene ID" value="B5F75_01555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="582" mass="66259" checksum="1767ADA2ED99AE55" modified="2017-08-30" version="1">MNLFENPFNVFGVSTRDNRKQILEIAKEKILSLDSGFVSDAKLMLTTPSKRINAEIAWLPGLSKNKCQEVMQFLANKNTDLNFIGTLPPLPALNVLVSMVNYWDNLQPKLVVELMIAVSTKYEDINVDNLTTILNEERDVAKIPAISSSSIVGHALEVHKNYCIEQIQYLLDKLSIKDLTSSMLLLMERCLKQEKRLTLVDALIDKSYAIKVQPYVLDQSDKIQKIASAINKKLSGNLTSSSVDEAVEEFIRELSVFDEMARPIQLSMKQRGLEHQGSKDIAYVARGLAIDLLNKAKKEELSEKLMKKVQELFIEIPSVEERVSADLQDLKEIQEDQKEWEKGISCSVSQWGWGHKLDISPTGITVSKSRHYKLEEISSIRYGVTKKYTNGIYTGTDTLVHFGTEKNGFETITWLDYKNGNWNKFVNCLYRAVGWRIFLAMISKLALGGNLYGVIYDDKVLLAKTHFYTPTEKQFFSWNEVVIFSQNGFFVIANKNDKAWQVSFSYQEDDNTHIIDNMIHEAFKKGAAKLSRAFGMTKERAKQSPQFDFGPEKNLDSLGYIFTWIFTIVGVIFLLVWMSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE1</accession>
    <name>A0A1Y4DEE1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">B5F75_01755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57523">
        <property type="protein sequence ID" value="OUO57523"/>
        <property type="gene ID" value="B5F75_01755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="57"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="131"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="275" mass="29416" checksum="CAF190AF19EB76A0" modified="2017-08-30" version="1">MIFKNASVFYNAHKTHTAPLAQEVCASLRAHGVHTDLITQLDGLTAETDLLVSMGGDGTMLYCARAAAPLGIPIFGINCGTLGFLAACEKEDALPTLQALLNGKCAVNERFMLHTRILAKGAKPREFLAFNDCVLRAAAPRAFLLEAKWNEKEMPSYFGDGVIVATPTGSTAYSLASGGPIVEPGVDVLAVTPICPHTLNQRPLILSAQGTLSLTPSFKNKADRALCSLDGQINLTLPAGACVQITRSALKAKLLCPPERGFFQILNRKLKWGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE6</accession>
    <name>A0A1Y4DEE6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57012">
        <property type="protein sequence ID" value="OUO57012"/>
        <property type="gene ID" value="B5F75_03970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="276" mass="31042" checksum="98AB590C3BA95412" modified="2017-08-30" version="1">MYASVWKRFFAFLIDAVVFAVLFWVLAQMMDNASVSLVLLVIIWLYYALLESSPLQASVGKIIMGIKVVDRRGRRLSFWQATERIFSKLVTNVTFYFGFFIAAFDKKKRTLHDRISHSAVISKNADFDPDAYAEPEEEASFTFITVVSVLLALVFVALMLVAVALPQYQKTERHVQLSRVLSALDYAARKQLKDAQAPGADPRVWLGEYKKCQRISPEKLSCDGFELLLEPGGVKASARNHAMDILYTLYYPFDGGPVQCTALTPQGEEICSTLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI0</accession>
    <name>A0A1Y4DEI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57305">
        <property type="protein sequence ID" value="OUO57305"/>
        <property type="gene ID" value="B5F75_00565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="596"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="623"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="650" mass="70773" checksum="E81142D3DD32F781" modified="2017-08-30" version="1">MSEQSTVISRPEPAALSVPSRAFTYRFFLSSCFLVLVLFSLTFHHSGVGIFILGLMNFLFCADVLVRSAAKDIWAGRFSFAVLISLCAGAGFVYASLNTFLTVKLFGPSVDLFLYSGLLVTLGLWAERRLTREKERARVFIKKIDDFLPKSGRLCVGRQFRKVFANELKKGDLIFVKPGERLAADGIVRQGKTSIDEQLITGNMLPTSKTEGSRVYAGTLNKSAEIYVEVTEVLAASALMSVIDAIKKGELLRSKFKSALDAFSGWVLLLLLLAAGGVYGFLLYTHGAGQWFHCLGIFLFILAAGCPAALVFAAVFPSFFTRSGARASKIKIQNVYALEELAQADTVFFDKTGTLTYGELRVSGVYPAKKISERQLLETIASAEQLVDGPFADAINLYAKKHKVKIQRVLCFDVLPGLGVQATCGEDKILAGRTQWLEEQGIKTSAKIATAAEAVVCVARNGKFLGFLTLSDELRPGAKETVALLKSLGKDVILISGDNEVSVGVIAQEAGIEKMNFNVLPKTKAEIVSNLRALGKKVVMVGDGFNDIIALLKADAGIVFSSGRNVYNNWVDVIVKRRDLFPISYLFTINKKLRRVVAMNVLLAVLLNGLVAAWLVGRMPQPSGWPLLVGGSLAVVLIVLLNSVRMLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ7</accession>
    <name>A0A1Y4DEJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57062">
        <property type="protein sequence ID" value="OUO57062"/>
        <property type="gene ID" value="B5F75_04230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012418356" evidence="3">
        <location>
            <begin position="21"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="317"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="473" mass="53001" checksum="CAEAC1F876044301" modified="2017-08-30" version="1">MKKYFTLTLLLVLASAGMQAATFRKEIPVRQHGKEEGMLLDLSKISMGTLNDVEEKKQYLSTVQLEKQRIQNYTLRMVYENAYLLYKHGDYQRAQEMAQTILSIDPNFKQAQTLARQASDMGTYGTISEAQVIEAKFQETIRLYDSGRLVEANDKLNEILTIQPGNSKAQSWKRKIDYDIAKEYTRRGDVAYEDGDYQKALDAWYNALLMRKDDPKLLAKISDTENKLRKQQVSDSMKQAMEFYNKGQFVEAYAVFERIIKIQPGDPRVQKYMSQLKNEIAAGYYNAGNKSYNSNRFDQAISYWTNAKKWGADSGTMDSLIKRARNAKENHLRVKQQQAIKAEQAAQKAEEAAKKAEEAATMEEEPIETVTVDPVPGLSEGAVIPGSIPGATGIGSSVGAVGTNETLPTLGGTTSRVSAEASAASRAKYIEGLDAFNQDDYERARQAWIVAKQLDPGNSDADLGLRKVEELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ8</accession>
    <name>A0A1Y4DEJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat-shock protein Hsp70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57486">
        <property type="protein sequence ID" value="OUO57486"/>
        <property type="gene ID" value="B5F75_01565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="831" mass="93136" checksum="8FBB554ED90A5498" modified="2017-08-30" version="1">MKHFIGIDLGTTNSAICSYDGEKTHIYQSPRELSEVTPSAIYINKRGVKYLGQEAYKMLLNDPENVAVRFKRFMGTNTPINIPNLGHPMSPEECSAEILKVLFNYLPEELRDSLDGGTVITVPAAFNQMQKEATLQAANMAGIGKVALMQEPVAAIMSVMKARTEDGIFIVYDLGGGTLDIAVAESINGHVSLLSHGGIAMCGGRDFDRAILEYVVYPWLLQNFKLPDTFWNDTAYGRLVRMSAYAAESAKIKLSSDDQAIINVMEEEMRMQDQEGKDIYLNIILTRERYDELVAAQVEESVKAVYETLEKAGLQPDDVARIVFVGGPTCYRPMREKISSALGIPANTDVNPMTAVAEGAALFAESIDWTSQEHARKNVKETLEVQEDVNLQFDYIARTPDIKTKLIMHSASLNENYELQIDSVESGWSSGRVKVKEGNMVELLLSKQGENNFKIFLFNEHGQNIPCEIDKITITRTAATVDSIPASYSVGIEVLDKVGGSSVLDYLVHSGDMLPKKGIKHFKAASTLKAGDPSALNFKIWEGDISMPITDNRLVGVMKISGTDFDEGVIYAGADIDVNYQMSDDGNIRLEISIPSIRSSFNSAKNFYSRQEGQKDYSELPQTIIFDAKSTKERADEMAAHIEDPELDGIRNTLEETSNLPAGLVDPEKAKEAEEKVLRAKRELASIRKKHLYEIRKIELDKAIDLFNTCFQKDVSPLEKSSFDNLVASAQRMLQRDTQEFEDYMFEIRTKIFSMLWKRDWFVVTRFKSLISTPFLFIDKVKFQELAHKGQEAIEMDQIQQLRQIVFELEDIRQGGSSIMEESDITNIVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK7</accession>
    <name>A0A1Y4DEK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56149">
        <property type="protein sequence ID" value="OUO56149"/>
        <property type="gene ID" value="B5F75_05890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="313" mass="34836" checksum="0A81E6E55F3B187B" modified="2017-08-30" version="1">MNSLRRLFLPVAAVLVYATAPSVLHAQKQILPLTRALQQETLRVAADRPLLSGFHGILSPRHWIGLNPATAVNPRLLERKVLAQFPRRVSPRHAFPGKQQIDAVIFDLDGTLLDSLSAWEHSGSNFLRTQGIVPPPGLDEELAKMSLLDGARLLKKRFHLPQPPEEILRLTLEPIRRHYYEDIQPKPGVLSLLQRLHAQGIKLCVATASDRELTEAALKRTGLLPYFDFILTCDEAGAGKRNPAVYQLARQKLGTPLERTLVVEDALYALQTARSAGFATAAISEPHAAKDQPALKETADYYFLSFLQCQLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM3</accession>
    <name>A0A1Y4DEM3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2807 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57623">
        <property type="protein sequence ID" value="OUO57623"/>
        <property type="gene ID" value="B5F75_02280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012056776" description="DUF2807 domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="39"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="267" mass="29056" checksum="93D8A10606A88270" modified="2017-08-30" version="1">MRKISLFLLAALLAAAPVFAESVTGRGRYVSRDVNHLPAFHAVEVRGDIEVDFMQDKITSVTVSGRENLVALSDVRVENGVLLVSFTRPVRVRGEYELRVAVRAPELTAVTASQSGEFDLRGSLDANQLVLTTDADSDISMDYVNADTITVAAYDRSDIELGRVHVQQVKATADGRADVDLSGTAEEAVLTNNGSGEIDADDLRAVTVRATTNASGKIKVNASEALYAQANGRGRIEYRGYPSTLRKEGNARKVVRDRDEDYDDYDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM4</accession>
    <name>A0A1Y4DEM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_00860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57355">
        <property type="protein sequence ID" value="OUO57355"/>
        <property type="gene ID" value="B5F75_00860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="147" mass="16228" checksum="4E95CF466A451CE1" modified="2017-08-30" version="1">MSAQIKLPEQNLVLLVGRLTRDPNVSFTQKGQAVCRCDIAVNRRYLDATTNEWKDDTVFVPVVVWGAAAERCKDRVKKGTPVQVEGRLTSSEYTDKNTGQTRKSLQVTARRIQILESGAAASYNQDAAPAAKDDVPTTDVMEDDVPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEP2</accession>
    <name>A0A1Y4DEP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57594">
        <property type="protein sequence ID" value="OUO57594"/>
        <property type="gene ID" value="B5F75_02125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013006077" evidence="1">
        <location>
            <begin position="20"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="225" mass="25004" checksum="EAD59B000B608414" modified="2017-08-30" version="1">MKNILFILIACLMVSVVNAAPTRDARQERRQQLVHEYLTRALSSADLNKENEFGDTPVFTAAQNGDVSAILRYGKRAANGSFLLRTGKNGNNVFHVARNAQTFQALARVLRDFYPGDYKIKIRQMMNQRNQLGETPVQAQINYGRADTFRIAFPYTDMYDKMMTVKTKLNKGGLIAEVAKTEAAVVVEMSKDASGRTIAQAARDNASAPGMAQVIAFFQNNAPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ4</accession>
    <name>A0A1Y4DEQ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57577">
        <property type="protein sequence ID" value="OUO57577"/>
        <property type="gene ID" value="B5F75_02040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012056773" evidence="2">
        <location>
            <begin position="20"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="139" mass="16404" checksum="36B5F1B9DF181A01" modified="2017-08-30" version="1">MKIFSLLLAFVLCAGFLTACNTNEKRKEKYNRKIYLTEEDYMEDLSKDAVRERRETPPNVESEYIFNVGPEEQRNIYFFDERQQPKVPGQPSEADYKKEKRLWKKPKRYTPEQYYGMQGTADAAAEDTSSETSYSGYDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES3</accession>
    <name>A0A1Y4DES3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="6">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="6">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="6">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">folD</name>
        <name evidence="9" type="ORF">B5F75_02035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="6"/>
    <dbReference type="EC" id="3.5.4.9" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57576">
        <property type="protein sequence ID" value="OUO57576"/>
        <property type="gene ID" value="B5F75_02035"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="7">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="8">
        <location>
            <begin position="140"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="290" mass="31295" checksum="36E4A80B51A304C8" modified="2017-08-30" version="1">MILEGRTLAAQIRESLPRRAEAVCQKLGRPIKLCAIGSTEDYGAYVYLKKEVEAARKLGVETQVFEINNQTPAAEFLALVEKLSADDKTDAILIPRPLPDHLAATDFADRLAPQKDIDGMSNINTGNLFLCKTWPEIQALKGFVACTAMAVIRLLTYHHVALEGAEAAVIGRSITVGRPLAHLLTCQNATVKICHTKTDLPRALKDADLVCSAAGTPGLIEADWLRPGTTVVDISTNWHNDSLCGDADPEKLQARGISYSPVPGGVGPVTLAVLLENIILSGERKLKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES5</accession>
    <name>A0A1Y4DES5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_02545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57673">
        <property type="protein sequence ID" value="OUO57673"/>
        <property type="gene ID" value="B5F75_02545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="146" mass="16197" checksum="472B01B4FD7BA876" modified="2017-08-30" version="1">MRQIDLHCNIDEDVFSLTIFLTRLLTGLVLLYVTIGSLLFYREFLYNATAIGLPLPVPVGLTVLVAELFLALFLILGWFTRPAAWLSVLCTAVMGVIFFASDFNKLYVALLVLLLTALLPAALLGPGKISLDYKHAVRRAQKSRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET6</accession>
    <name>A0A1Y4DET6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_02605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57683">
        <property type="protein sequence ID" value="OUO57683"/>
        <property type="gene ID" value="B5F75_02605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="228" mass="24607" checksum="4EF3E20F142CC2D2" modified="2017-08-30" version="1">MDWGLLVNSFIGMLSILNPIGNVPIFLEHVENEPPKVQRAVALMMALAIFLLLTAFFVFGNRILTLFGITIPAFRLAGSIIILIVGLRMLQGKSKFESHGIETAAAQGNTFDQARNRLSHILVPVAMPLFIGPGSITTAILYAEKTTTFSMAMMMIGVLFLSSAIVGVCLVGSRYIFNKIGPNGTQIVIRFMGMILCAIAMQFMIDGVAQLLPGVLDSTFTHAAGAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU1</accession>
    <name>A0A1Y4DEU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Epoxyqueuosine reductase QueH</fullName>
            <ecNumber evidence="5 12">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Queuosine biosynthesis protein QueH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">queH</name>
        <name evidence="13" type="ORF">B5F75_01235</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the QueH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="5 12"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57425">
        <property type="protein sequence ID" value="OUO57425"/>
        <property type="gene ID" value="B5F75_01235"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02089">
        <property type="entry name" value="QueH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003828">
        <property type="entry name" value="QueH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36701">
        <property type="entry name" value="PTHR36701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02677">
        <property type="entry name" value="QueH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="23485" checksum="AB3962CD45DDF604" modified="2017-08-30" version="1">MRLPYRFCYTIYMQLPAKLLVLSCCAPCSCAVMKKLSQDGVDVTVLFYNPNIYPTAEYEKRRDEQKRACAALGVKFAELPYEPEVWNECVKGLENEPERGKRCWACFALRLKRAAEYAREHKFDAFASVLGVSRYKDLDQVNDAARWAWMHVGKPYVAVNWRKGGLEELRRALIEELHLYKQEYCGCKYSIRKKEENEKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU3</accession>
    <name>A0A1Y4DEU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57596">
        <property type="protein sequence ID" value="OUO57596"/>
        <property type="gene ID" value="B5F75_02145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="305" mass="33385" checksum="7DDF46E2C631559D" modified="2017-08-30" version="1">MKKEELMKLLRNPAKYRKDKKAAQPQQTKPQQEPARKLQDKLLWGVGLGVAALVAVTLLVISSAQNRADNLTAALDPEQVKGLSVAETEFNPNTGVTYIQVSEGQDRNVAVSNLGTTLPIISRFNYRSFTPDNYEVIGAAPWALTTNFSSNISDPDLMRYLLSNDTMIQAFLARPDVAPLLEDPQLLLAFTKDNAAMEEFFDSDTVKQVLANEKMVRGVAGSRFMSYLLISKAVKYFRDRPQEAAAAIAANPYLKEVQQNPHVQAAVRENPYLKKIANIILGPAAAPAKTTGKPAAAGKTAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY0</accession>
    <name>A0A1Y4DEY0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57636">
        <property type="protein sequence ID" value="OUO57636"/>
        <property type="gene ID" value="B5F75_02345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="82" mass="9039" checksum="B7E70A754F9BDDB8" modified="2017-08-30" version="1">MTHTPSFAQQSAAVLFKAFFMLIKTLFVLLALTVGALVAGQSSVAPVSVRLLSAYGMEYAVATFKPYRHLFPEPYLIDLENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF19</accession>
    <name>A0A1Y4DF19_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
            <ecNumber evidence="2">1.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56309">
        <property type="protein sequence ID" value="OUO56309"/>
        <property type="gene ID" value="B5F75_06755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="491" mass="54270" checksum="3102FAE34CCA0CC3" modified="2017-08-30" version="1">MPMRWGVFKMEPILTHNQLSIEKSRPGRRGVRFEWAQKPASAYVPQEYLRKTAPKLPELSEFETVRHFTRLSELNYCLDGEFYPLGSCTMKYNPKAYDALSALEGFTQMHPFAPESSVQGTLEMMYHFQELLKQVTGFAAFTLQPAAGAQGELTGILTARAYHDAHKDFNRTEVIVPDTAHGTNPATAHMAGYTVVNIPSAPDGCVDKEALQKALSDKTAVVMLTVPNTVGLFEKDIREIAQMVHKAGALFYLDGANFNALAGLVKPADLGADLMHLNVHKSFAAPHGGGGPGAGPVGAAAHVAPFLPKPIVEYKNGKYTLSGKMPKSLGKMKAFYGNIAVCLRGYCYLRQFDDSTFKEIAENAILNANYVRAALKGKFNAFFDRTCMHECVLSIRPAEMNGVHTSDIAKRLLDYGFYAPTIYFPLIVPEAMMVEPTETESKQMLDAFVAVMEKIYDEIQTEPQTVKDAPHSQCVARIDEVSAAREPNLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF29</accession>
    <name>A0A1Y4DF29_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57686">
        <property type="protein sequence ID" value="OUO57686"/>
        <property type="gene ID" value="B5F75_02620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="13239" checksum="6C27779FD69E1EA2" modified="2017-08-30" version="1">MKKRILIVEDEASIIDLLTLVLTREGYEVFSCQTGRDAIATIKKVHPHLVILDVMLPGLDGASIVKIMSEDETLSSIPVIITSALVESEKLFSTHPQVKAFCSKPFVLTDFVAKAKQALGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF37</accession>
    <name>A0A1Y4DF37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57696">
        <property type="protein sequence ID" value="OUO57696"/>
        <property type="gene ID" value="B5F75_02670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="187" mass="20036" checksum="0D243833A1C5D6FA" modified="2017-08-30" version="1">MHGLKTYFHYMEDPAAALKEWVQARSLAWACAGYLAAALGWVLFFNIGDGISAAAFVGKWAVVFAAELTAGFFMAAVCGMFLDFCRVKASPAELFSLVGSAGFIKGLFIVFALWNAMWPQARLGGLAAAAVLLVLGLQLGYLTRGLMRLYGVSAWKALGAWLFGFIPLCAAGLLGCIFAAWGLMLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFA9</accession>
    <name>A0A1Y4DFA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56359">
        <property type="protein sequence ID" value="OUO56359"/>
        <property type="gene ID" value="B5F75_05915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="134" mass="15119" checksum="C8A6A5CBF8993084" modified="2017-08-30" version="1">MKKAPIDTIFNQGEPNPYGKFFTGQTYLNMLSPKDDVFNAPIGNVTFEPGARTHWHKHDGGQILLVLNGEGRYQEKGKEIQILHKGDIVRIAPGVTHWHGAAPESWFVHISLETNAHQNGQTEWLDAVTDEQYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFB3</accession>
    <name>A0A1Y4DFB3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">DNA ligase</fullName>
            <ecNumber evidence="9 10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ligA</name>
        <name evidence="12" type="ORF">B5F75_02290</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="9 10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57625">
        <property type="protein sequence ID" value="OUO57625"/>
        <property type="gene ID" value="B5F75_02290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018239">
        <property type="entry name" value="DNA_ligase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01055">
        <property type="entry name" value="DNA_LIGASE_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="581"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="9">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="31"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="423"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="661" mass="73456" checksum="E3AF750BF8698E31" modified="2017-08-30" version="1">MHPKEEIERLKKLINYHNNLYYNLDNPILSDTQYDELYKQLKDLEDQYPQYRTKNSPTQRVGGQAGTMFSPVRHTTPMLSLDNSYSADDIREWYARAEKTLQRNDFEMVVEGKIDGVSCSLTYENGILVTAASRGDGKVGEDITANARTVCNIPQKIENAPAGLLEIRGEVYLDKKDLEELNRKQQLAGENTFANTRNAAAGSLRQKDPQITAQRPLKFFAHSFGAGNIAADSFSGFIDLCRQWGFSVCPARTKTTQISEVIRFYNQFEASRRQLPFDVDGLVVKVNRFEFQRILGVTAKSPRWAIAFKYPAPQATTAVNHILFSVGRSGVITPVAELQPVPVGGVTISNATLHNFDEIKRLGVRVGDTVIVERAGEVIPKIIKVVEHKGQEEVLPPTVCPSCGGPVYKEPDEVGYYCVNPSCPAQLRARLLHFASRGAMDIDGLGDVVMDQLLENHYVSDFADIYNLTFLHLLNLENFKDKKAQNLLDAIEASKQKPLSRLLFALGIAFVGAKTAEILADRFRTLDSLKNASLEDLQNVREVGEIVSKSIYDFFRNPRAQEQIERLRAAGLNFTQPKKELSGNILDGKTLVFTGELKTMTRPQAELLAKQYGGKASSSVSKKTAYVVAGEAAGSKLAKARELGVPVLTEEEFLKLIGKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFM3</accession>
    <name>A0A1Y4DFM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57442">
        <property type="protein sequence ID" value="OUO57442"/>
        <property type="gene ID" value="B5F75_01330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="123" mass="13496" checksum="F65509E84C27F6F5" modified="2017-08-30" version="1">MHLIHLHNIPADIHAAQGHNSGFTLIELLVVVLIIGILAAVALPEYTKAVEESRLSEGVMAVEEIAKANRVYYMANGQYSRDINALDFAYAGSGKYGNLLEANVGKHFIFSASAWGRRDISLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG63</accession>
    <name>A0A1Y4DG63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56649">
        <property type="protein sequence ID" value="OUO56649"/>
        <property type="gene ID" value="B5F75_05515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="19284" checksum="E8E0117241ADC793" modified="2017-08-30" version="1">MAGTPSKECQNIVLSGIKKMLIAPLGAEKTAARDVGFTNGNVTLTAAFEYADVMVDQSLIPVRRIATAVNYNFAAPLASMSLENLAIGLGVEFGENGQATLAQERYYQVWLETDGPVNDEGEKAVREIYFPKIALGGTTELAFSRTDAQTANLEGVIINCPTEDGNANFLQITDTYPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH21</accession>
    <name>A0A1Y4DH21_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tellurium resistance protein TerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56228">
        <property type="protein sequence ID" value="OUO56228"/>
        <property type="gene ID" value="B5F75_06315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="313" mass="35033" checksum="D84C8788782030A4" modified="2017-08-30" version="1">MEPVTTTVSVLMWIAFWVIVLTALFVDLAVLNKHHGKVNMKEAALMVCAWVSLALLFGGAIWLVEGPRHALEFYTGYVLEYSLSIDNMFVFIMIFGYFAIPHELQPKALLWGILGAVVMRFIFIFLGVKLISMFSWTIYVFGALLIFTAAKMLLQKEDEKFDPSQAFVLKALKKVMPLKTDYHGENFFVLENAKRYATPLFAAVLVIEMSDLIFAVDSIPAVLSITQDTFLVYSSNIFAIIGLRSLYFLLSGMAGKFPYLKYGISVILFFVGVKMLISHHFKIPVLASLGVIVAILAVSILASKFFPPKPAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH64</accession>
    <name>A0A1Y4DH64_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56268">
        <property type="protein sequence ID" value="OUO56268"/>
        <property type="gene ID" value="B5F75_06535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013096533" evidence="1">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="309" mass="35029" checksum="9A72050F9071E5E7" modified="2017-08-30" version="1">MKKLLLLLLFLPLSAAALSDWAYTDAEQEQHKLRQTAEKRAFKQVKAEVKAGFSDSLADLADLYYNGIGTKQNYKKAYKYYQQAAQKGDAYAAYSQAFMLMYGQGVKKDPQLAFNQLETLAQEGSSWAALEMYRAYQNGNGCPKDPVQARHWLETAANYRLPAALLYLGMETLPEDPARGFFLLKEAADLENARAQYLTARCYREGTGTAVHPHQAFNYMLLAAKQHYGPAQWEIAQWYRQGYGTEKSPYQEFRWTRLAAQAGEKPAQQRLAQMYQEGIGTPVHKKLAQKWAKEALKKTEQEASYGTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHE9</accession>
    <name>A0A1Y4DHE9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplB</name>
        <name evidence="7" type="ORF">B5F75_06960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56348">
        <property type="protein sequence ID" value="OUO56348"/>
        <property type="gene ID" value="B5F75_06960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="279" mass="30516" checksum="DF1CA8209B12D0B6" modified="2017-08-30" version="1">MPIKSFRPYTPSRRTITVSDYSDITKTTPEKSLTKGLRKTGGRNNTGMIMVRHIGGGHRRAYRQIDFKREKYGIPAKVVSIEYDPNRSARICLLNYADGEKRYILHPLGVKVGDVLMSGPAADIKVGNCLALKNIPEGTFIHAIELKVGKGAQLARSAGSQAQLMAKEADYAHIKMPSGEIRLVPSACCATIGQVGNIDHGNIVIGNAGRNRHRGERPTVRGSAMNAVDHPMGGGRGHGKGGNIPRSPWNQQTRGLKTRSTKKAFGWMIISDRRKNKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHT2</accession>
    <name>A0A1Y4DHT2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57229">
        <property type="protein sequence ID" value="OUO57229"/>
        <property type="gene ID" value="B5F75_00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="33"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="236"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="438" mass="45463" checksum="122855DB9542494C" modified="2017-08-30" version="1">MKPEKFTPNPLALIPLGVFLLSYLAVSLAAGDFYKMPITVAFVLSSVVAVAMSKGGSLHNRIELFCKGAANSNIMLMVLIFILAGAFAQTAKAMGAVDATVNLTLAILPGNVLAAGVFLAACVISVSVGTSVGTIVALTPVAAGLSAQTGISPALMSAVVVSGAMFGDNLSFISDTTIVATRTQGCKMADKFKTNFHIVMPFAILTTILYIFLGSGAQSSFASGPISWVKVLPYVIVLAAAVMGVNVMLVLLGGTVLCGLIGLMTGAFDIWGWTTSMGAGINAMGELIIVTLLAGGMLEMIRYNGGLAWIIQKMTAKISSRRGAELSIAGVISFANLCTANNTIALIMAGPIAKEIAQRFGIAPNRSASLLDIFSCFVQGVIPYGAQLLMAASLSGVSPVSIMRYLYYPYLLGIGALLAIWLGFPRTHAPQQAAKTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHV7</accession>
    <name>A0A1Y4DHV7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">B5F75_00260</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57249">
        <property type="protein sequence ID" value="OUO57249"/>
        <property type="gene ID" value="B5F75_00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="26"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="203"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="109"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="318" mass="34602" checksum="6CCD373CE3C096E7" modified="2017-08-30" version="1">MNKLKTIFFGTPALSVPYLDLFHQLTDVQLVVTQADKPRGRGMEISPCPVKKRALELGLPVLSPEKLKDAFSQIAALPFDLGLAVAYGKIFRPDFLALPKLGILNVHFSLLPHLRGAAPVQQALIQGYTQTGISIFWIRPGMDDGPLFLQKEIAILPQDNAQTLFEKLIPLGLSGLQTALEQIAQGHLVQTPQQGEPTLAPMLQKEDALLRPAELSAQSLHNRVRGLACGPKPKVPFTHNGKTEWLQLVKTEISSSPAPQTADPGTVLCIERNRGILVKCKEGSIWFNEVHPAGKKPMAAEAFANGRGLKPGDGAFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHX7</accession>
    <name>A0A1Y4DHX7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57269">
        <property type="protein sequence ID" value="OUO57269"/>
        <property type="gene ID" value="B5F75_00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="56"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="312"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="387" mass="41278" checksum="D129CBE2110776AA" modified="2017-08-30" version="1">MNDFLITPVCAVTPQDTLQQAAIWIQNGHIFRILDAEELPPQAQQLPRIEAKGCVAIAGFIDLHIHGFAGFGPELADPQALLNMSEALAQTGVCAFCPTLYCAKPAEMEKLLRKLRPAVGLETGAKIIGFHLEGPFISPKKPGVMKPQDIAPADLKAFQKICEAGDGTIVSVTLAPELPGIEPVIDYAKQNGILLQAGHTNATYDEFLLGAARGVTHVTHLFNAMSPFNHREPGVAGAALMHPGISCELIADGVHVHPDIVSFLRTVKPIEKIIAITDALLPTGQKEGPFLANAEEVVFKGGVWRRRKDGVIAGSALTMAQAFKTLLDCGYTLPQAAACTSSNAARLIGLSKYGALEEGASADIVLLNASFEPEKVFLRGQMRVPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI34</accession>
    <name>A0A1Y4DI34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CpXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56608">
        <property type="protein sequence ID" value="OUO56608"/>
        <property type="gene ID" value="B5F75_05295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025682">
        <property type="entry name" value="CpXC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14353">
        <property type="entry name" value="CpXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpXC" evidence="1">
        <location>
            <begin position="11"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="213" mass="23737" checksum="81435266EAB92B04" modified="2017-08-30" version="1">MKSIKNEAAAHCPNHCEPFDVEYWSLVSADQDPDLKSAIMGGELNLVQCPECGTFFHHDGDLIYFDAPAELLVFVFSEKDRPREAQLRERMQKDYELIKNTLLKPLHMDYPPICVFGLDALKTLLQHEEVESYESEAVAAAAAAMGMQVARLKPSYARANHFPLYVPAPAPSKTANDYAVAASKVLKSGLKSLLLRNFEDRMSQEGALPPQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIH8</accession>
    <name>A0A1Y4DIH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56120">
        <property type="protein sequence ID" value="OUO56120"/>
        <property type="gene ID" value="B5F75_05730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019993">
        <property type="entry name" value="RecB_nuclease_TM0106_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03491">
        <property type="entry name" value="TIGR03491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="315"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="496" mass="57295" checksum="A9A7DCA611B2609B" modified="2017-08-30" version="1">MTDNELQDLFQFLSAGRTPGKQDFNASKMFSLLEDPFSIWCSFHAPKEEAVPEPNRYESLKIRTDRNARDQWIKAEFPGVVFVSGEDETARFKNTLSAMARGESAIANALLWNLPENTYGSLNLLVRSDAAPSLFGPYHYHIFQFKRAHDLKEHYALQVSLLNHMLGKTQRYTPAQMRVFLKDRTLDVTYQDHQERLERELAFWRSIRDGLAKPEAHKPPKAASAPWRVYANKVVAQSKDLLMLPGLNTEMRQCLKINGIFNTDDVARAGLEKLRGILEEPHATDSYYNALAYLHHKPVLREEGHFPPPAKKYNLYFDFEATETFTKDNVSFVYLIGIWDKEADKYVSFVAKTPEEEIKIFEQFYDYVRDFSDTALYHWTEYEVKKMKNLAAKNPQDAEKLKALCNICFDLKVAVNKQFYLPAPSFSLKAAAPAFGFNWRQDDCGAMDSMVYFTNWLKTGNDELLKKVLMYNEDDCKAMLDLENKLKAADVLHFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIK8</accession>
    <name>A0A1Y4DIK8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Colicin M resistance protein CbrA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57499">
        <property type="protein sequence ID" value="OUO57499"/>
        <property type="gene ID" value="B5F75_01630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="363" mass="40741" checksum="C8804A3B1071AE2A" modified="2017-08-30" version="1">MARDTQAGEAMFDVIIIGLGPAGSTLARLLSGKQKVLCLDKKTDASDSFSKPCGGLLAPDAQKALARFDLTLPKSVLVDPQLFSVRTIDLASGLCRHYPRFYINMNRHRFDRWLISLIPNSVSVQAGAQVVRAVRETDGSFSVTFRQNGSLHTARGRRLVGADGADSFVRRTFFPRHAIRSYTAVQQWFADTHKSPFYSCIFDPAETDCYAWSVSKDGYFIFGGAYPVQNSRARFERQKKKLERLGLQFGNPLKTEACRVLRPAGWKEFCLGGNGVFLIGEAAGFISPSSLEGISSAFESARRLADSFEQTPGRTEHRRYARNTLRLRLKLWSKLFKCPFMYRPLLRKWVMKSGLQSISVLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIY6</accession>
    <name>A0A1Y4DIY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rimP</name>
        <name evidence="6" type="ORF">B5F75_03430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56908">
        <property type="protein sequence ID" value="OUO56908"/>
        <property type="gene ID" value="B5F75_03430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01734">
        <property type="entry name" value="YlxS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036847">
        <property type="entry name" value="RimP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74942">
        <property type="entry name" value="SSF74942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="11"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="85"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="16971" checksum="5DC92AD66202C1E6" modified="2017-08-30" version="1">MRDPKTIEETVAKALAPQEVELVDLVIQNQGRKKVLQFFVDKVGGITLDDCGELTDKIDSILEMENLMDGAYILEVSSPGVQRVLKKPEHFKRFVGQRAKIVLKVPLEGRGSFTGIIASADDDAFVLDDGTNQFRFSYDNIKKANLDPVLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ40</accession>
    <name>A0A1Y4DJ40_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ORF">B5F75_06870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56330">
        <property type="protein sequence ID" value="OUO56330"/>
        <property type="gene ID" value="B5F75_06870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="250" mass="26927" checksum="AC7498DF2B01BB6F" modified="2017-08-30" version="1">MIEVKNDNEIQKMREAGKVTAAVLKQMTEMVKPGISTLDLDQAAEKTIRSFGATPLFLGYYGFPGSICASVNEEVVHGIPKKDRILKSGDIISIDTGARLDGFCSDAAITLGVGKVSDEAQRLMDVTKKSLYKAIGQVKPGRRLGDVQHAVETFAISQGMGVVRDYCGHGIGRNMHEEPSIPNFGKPGTGPLLEKGMVLAIEPMLTAGTFRVRELDDGWTVVTRDGSYAAHFEHTVAVTANGSEILTAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJB1</accession>
    <name>A0A1Y4DJB1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Death domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57028">
        <property type="protein sequence ID" value="OUO57028"/>
        <property type="gene ID" value="B5F75_04060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000488">
        <property type="entry name" value="Death_domain"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50017">
        <property type="entry name" value="DEATH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Death" evidence="2">
        <location>
            <begin position="72"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="21530" checksum="6B7EB86B03426AE2" modified="2017-08-30" version="1">MNPAETAAPQAAPQEPSDLNAPSARPQADPVPGREETPPDQNTSRTDAAPDPAAYPNLQLPEDVSFPEAALEDFKTLSQEMGLSEDQVQKLLDLEARFVRSGAQHGAEEKRQLLERWAEQTQALYGAQCGEVISLAVRAADAFGGPELRGLLEATGLGNHPVIVRTFYEIGKSISEDVLPGGKPAAPQDKTFAEALYGKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJQ6</accession>
    <name>A0A1Y4DJQ6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fructose-1,6-bisphosphate aldolase, class II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56570">
        <property type="protein sequence ID" value="OUO56570"/>
        <property type="gene ID" value="B5F75_05090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011289">
        <property type="entry name" value="Fruc_bis_ald_class-2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01859">
        <property type="entry name" value="fruc_bis_ald"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="325" mass="35794" checksum="3548BE25F47CEEA5" modified="2017-08-30" version="1">MTVSYKDLGLVNTRQMFKDAMAGGYAIPAYNFNNMEQLQAIVTACVQTGSPVILQVSKGARQYANATLLRWMARGAVEMMKEIGKPVPLCLHLDHGDSFELCKDCIDNGFSSVMIDGSHLPYEENVALTKKVVDYAHQHDVTVEGELGVLAGIEDEVSAEHHTYTDPAQVEDFVKRTGVDSLAISIGTSHGAYKFKVKPGEKLPELRFDILEEVSKRLPGFPIVLHGSSSVPQWAVKQINEYGGKLEDTAGIPEEQLRKAAKSAVCKINVDSDGRLVMTATIRKIFATKPSEFDPRKYLGPAREELIKMYAEKNENVFGSAGRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKG6</accession>
    <name>A0A1Y4DKG6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX homolog</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">htpX</name>
        <name evidence="14" type="ORF">B5F75_01200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57418">
        <property type="protein sequence ID" value="OUO57418"/>
        <property type="gene ID" value="B5F75_01200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4 12" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="13">
        <location>
            <begin position="122"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="38501" checksum="75D86E525650423A" modified="2017-08-30" version="1">MATIYDHIAQNKRRTWLLVLLFPITFVVLGYVFLFGFYQLASTPQGQSSYSGSYYSQTAPRSYYSQTPAEEGSSALEHANQTALYVLPFLWVGAVLWIVIAYFAGDRMLLHGARAIEIHREDQPEIYNLVENLCISQGLPTPRIYIIDDESLNAFATGRDPEHASVALTKGIVQKLERVELEGVVAHELAHIQNRDIRLMLITVAGISFFTFLSEICFRMGLRASRRSSKNSGGAAALMFVLGIFFAIYGYLVAPLIRLAVSRTREFQADATGALMTRHPAALARALRKISADPRVEALDEHASMAAMCIENPLQKNGLFASLSGLFATHPPVEERIAALQEMDGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKI4</accession>
    <name>A0A1Y4DKI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">B5F75_02905</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56810">
        <property type="protein sequence ID" value="OUO56810"/>
        <property type="gene ID" value="B5F75_02905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="193" mass="21985" checksum="FC458A76A3BBFF56" modified="2017-08-30" version="1">MFTSNFNPWHHVSPGDKRTLPDVVNGVIEIPKGTRAKYELDKESGLLRLDRVLYSSVYYPANYGFIPRTYGADRDPLDILILSQAEVVPLCIVPARIIGVMRMLDNGEADDKIIGVAQGDPNVSHYTDISQLPEHLVSETMSFFEDYKKLENKSVVVEKIFDKKTAVKILQEAFIAYEEKFVTYSNFSHYCEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKR3</accession>
    <name>A0A1Y4DKR3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">5_nucleotid_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57518">
        <property type="protein sequence ID" value="OUO57518"/>
        <property type="gene ID" value="B5F75_01730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011833711" description="5_nucleotid_C domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="2">
        <location>
            <begin position="324"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="496" mass="55082" checksum="E88957451DC0BFAD" modified="2017-08-30" version="1">MRGKKLFLLLAVVLLAGGCGREDLTPIDVYYTADVQGFYWSRPEPRWDNREAGGYAVLKNFLQSREGEYLLFDGGSWFGSAPEGTMTKGAYVAELARTLPYTAGTISDKDLVYGWPSLRGIVRELPYPFVVSNLRLENQLPWPLHDYQIRTVNGIKIGIFGLIDPQAINKNKSRLLGLRALDAVETAQQMASLLKEKGVDYIILLSSIGATQKDGLSDTALAEETTGIDLILSSNKDRENAETDQINKTFIVYPGSKLDSVGHIKLLFDKNKQLREITFEDVPLLKETFGEDAAVAKQASALRAATRKKMNARVAEVPVEIPNALAQESALGDLLAQCLHKWARLDGAVINSDSIRSPLPAGTLTEYDLYKTYPYGDNITFITIKGEAFLKAMELSLNAKDNFPQIAGFSVSYAQTPAGRKIRQIVLDNGRIVRPQETYRFAVTDHVLAGGFGHDGFIDSLEFKNTFVEARQIMRSCLYRQKTVQAPARGRWKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKT1</accession>
    <name>A0A1Y4DKT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infB</name>
        <name evidence="11" type="ORF">B5F75_03440</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56910">
        <property type="protein sequence ID" value="OUO56910"/>
        <property type="gene ID" value="B5F75_03440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="273"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="7">
        <location>
            <begin position="276"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="129"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="282"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="328"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="382"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="776" mass="84143" checksum="8D7A010FBC4859CA" modified="2017-08-30" version="1">MTTKKTTNSEEESSAKKKPAAKKTAAKTTAKKTTAKKTASKTTAAKKTTAKKTTAKTTAAKKTTAKKTVKKVASAEQEAPQTQPVQDVQPAKESPVSATQPVVKPAQPQAAQPAPAQAPQAVSQPKPAQPQVQPKPVPQPAQPQVQPKPASQPAQPVSQPKPAPTHPQGPRHGHHHGEQQAPKQPERDPKCIRIVGQPTVKELAEKMNFKTNDFIKKLMMMGIFATINQRLEKDMIELIVDECGFKAEMAEEDLDKETVALMETPDDPASLKPRSPVITIMGHVDHGKTSLLDAIRKSNVAAGEEGAITQHIGAYRVTTPRGTLTFLDTPGHEAFTAMRARGAQATDIVVLVVSATDGIMPQTIEAMEHAKAAGAPIIVAINKIDLPGANPDRVKQDLAARGLVPEEWQGNTIFVEISAKKHINIDKLLEMISLQAEMMELKANPDRPGVGVILESKRDNKRGVVATVLVQKGTMKVGDPFIVGTNYGRIRALIDENSQRYQKIGPSTPAEILGINGEPPQVGDTLYIMPSEKEARYAAEKRKLAQKEDSQAHRKQMSLMSLGKNDENGNRVKKLQLILKADVQGSIEAIKDALLRIPSDEVELDIILSAPGNINESDILLAKASNAVVIGFHVDVENKAQAEAEREGIEIRRYTIIFELLEDIKAAMEGLLEPDVVETVVGTATIKKVMKLSSGLISGSLVESGTIIRGYEVRIKRNGQEVGHGKIGGLKRFKDDVKEVEKGYECGILVEGFKGVAEGDTIECFRKDNVTRRIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL22</accession>
    <name>A0A1Y4DL22_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pantothenate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57628">
        <property type="protein sequence ID" value="OUO57628"/>
        <property type="gene ID" value="B5F75_02305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PTHR12280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="281" mass="28928" checksum="9790EAF4863C0D6C" modified="2017-08-30" version="1">MSVVIGIDVGGSTTKIVGYTDAGKLVSMLKVEAADPLTSAYGALGKFINENGLALSDVQQIILTGVGSSLFKKNIYGIATSKVDEFEAIGSGGLALSGKKEGLIVSMGTGTAFVRAGKDGIRHIGGSGVGGGTVLGLCGKLCGATSFKTVVEMAEGGRLGQVDLNISDISTGVISTLTPDTTASNFGKMEDGVTPEDLTVGVLNMVFQTIGMMAVFACRNDSVKDVILTGTLTLVPFAKHVFQALHKMHGVNFIIPQNAIYATATGAALSYLYKNGKIHVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL56</accession>
    <name>A0A1Y4DL56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b</fullName>
            <shortName evidence="11">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpF</name>
        <name evidence="14" type="ORF">B5F75_02470</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57658">
        <property type="protein sequence ID" value="OUO57658"/>
        <property type="gene ID" value="B5F75_02470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="38"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="164" mass="18175" checksum="CD023412BD1D6949" modified="2017-08-30" version="1">MEDLLKPDYGVLVLTVCNFLLLVYLLKKFAWNLIIGGLEKREQQIADDKKQAQDARAAAETLKQELDAKLAQISEEASKRMAEAVKIGEKQKEQILSAAKEQSDRLLAQAKAQIEAEKNKALADVRGEIARTAVLAASKVVQQQMSEQSAKSVVDRVLEEIKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL96</accession>
    <name>A0A1Y4DL96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57070">
        <property type="protein sequence ID" value="OUO57070"/>
        <property type="gene ID" value="B5F75_04275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="304" mass="33042" checksum="A4B93E8243C35551" modified="2017-08-30" version="1">MNAWAIDSDAGTSASAFLKIDAGSPRAQALGNAFVSIADGPEALFWNPAGAASATTRELQFSYLDYLQGYKARTLAYLQPIGKTIIGVTVNYMDMDGFDFRDDTGAPNPEVGTPVQNFVGSLSIARGFFDQKLQIGGTAKYISEKLDSDHYNNVGFDVGAKLRLVNWLGLGGALVNIGDKEEMPRGLRLGADLNTRYFTISGEYMKYRDDKARYGVGLEIHIPEDLLQVARFDLRVGYYTRENTGINEQDSWVGDLGLAETSKVSFGFGIYSSELFGYGASIDYAVTPFGALGTSQQIALAIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLS1</accession>
    <name>A0A1Y4DLS1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57250">
        <property type="protein sequence ID" value="OUO57250"/>
        <property type="gene ID" value="B5F75_00265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="2">
        <location>
            <begin position="53"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="2">
        <location>
            <begin position="120"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="2">
        <location>
            <begin position="191"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="333" mass="36557" checksum="5D7815ABE562023C" modified="2017-08-30" version="1">MPANNDQNFEDFLNKAKSSSRTKWVVVGLIVLFFAALIFVSIDWVFGALVHTRKEVSVPDITKKSITQALNMLATNNLAMKQAGVEFAQDVPPGSILRQIPSAGSTVREGRVIRVWISQGDEMVFVPNTVGSDLRSAQLAVRQAGLLVDKVDNAYSLTYEKGLIVAQNPKPDSMVQKGEKVSLVLSNGAPPASVVLVPNFKSKKLAEATLWASSQNINLIIKEDANSVFPNGTIAEQRPEADSQIAPGTNLEVIVSRRETADNEKSYHLHYEMPQGKNASRVRVVVEDATGEMEIMNETKQPGSKIDLEIPYTDRAAVRVFVDGILVREREVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMC1</accession>
    <name>A0A1Y4DMC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Gln_deamidase_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57440">
        <property type="protein sequence ID" value="OUO57440"/>
        <property type="gene ID" value="B5F75_01320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041325">
        <property type="entry name" value="Gln_deamidase_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18626">
        <property type="entry name" value="Gln_deamidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln_deamidase_2" evidence="1">
        <location>
            <begin position="273"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="421" mass="48357" checksum="DD48B4E469F3F7D4" modified="2017-08-30" version="1">MSLVAFLYLFYTFNMKRYLSILWGAVLLAGCCAFAYGAPPVQEGCLKKLVRRLQPAAGEPGRAAMNRLRWMRFYLPTVKIAEREGFWERLFHSFSEADKQRAVASYLYQMYISSAVYGGEIPPRLTVNYLGVLNGLERLEANFDAREALAYYQKNKAEIKKWLVQFFKEAALPVYQPENARNDITEKAFLKTLARSTLEHGRAGYVLAAPRWNEPLPQADQKWLQEVQRLAAADIRQKVVLYEENAASLSSLDKLSGQYTDGGKVYLFRPAGKECAACSYLTCSRVCRQVQAQPSRNWGLMQVYQLQLRPLKASQLRPASGTKFFSPQGKAYPDWFYHEAVLVILNHGKRHIPVVLDPFLAEGPMAFSQWLAHFSPQHTVLYAYPFQRWSDTEERLVRPDKVKGNKIWKDGRSYKPYPVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMI6</accession>
    <name>A0A1Y4DMI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57510">
        <property type="protein sequence ID" value="OUO57510"/>
        <property type="gene ID" value="B5F75_01690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010992440" evidence="2">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="286" mass="32323" checksum="896CE664C3A0BDD5" modified="2017-08-30" version="1">MQIKWLAVLCLLFSGAGWLQAQAEAPEIVIEMHGEPSPVRESVSIWDKNARQLTKLFRGKNRTYVLYHVENVSSKDTTLSAQDGTEYAFVQYGSNDTDYRKFLFKAEDPQTFVACAADIKDVLAVNKKYKVNLGVSLRDFLRQYEEKATLMNLADNAAGKVYQVYQLNYSDINHKTPSPHYFVFEEDALLQTYDSDDAYYQFVGQISNNNKQLTAQQQAQQQARQEKLQQARQEALRRQNQPVRKALVSGGTAYDQAYMPRAVNATPLPALTPSKLPAGTPLPTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMW6</accession>
    <name>A0A1Y4DMW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="9">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpA</name>
        <name evidence="13" type="ORF">B5F75_02480</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57660">
        <property type="protein sequence ID" value="OUO57660"/>
        <property type="gene ID" value="B5F75_02480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="12">
        <location>
            <begin position="25"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="10">
        <location>
            <begin position="149"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="11">
        <location>
            <begin position="375"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="9">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="511" mass="55448" checksum="280A2B1163FB43E6" modified="2017-08-30" version="1">MAIRPEEITNIIKEKIEHFDTSADVNEVGTVIQVGDGIARVHGLNNVKASELVDFGNGVQGMALNLEYDNVGCVLMGPDHLVHEGGLVKRTGEVISIPVGADMIGRVVDPLGHALDGKGAIKADKKMPLDIVAPGIIDRQPVKQPLQTGIKAIDAMVPIGKGQRELIIGDRQTGKTAIAVDAIINQKNIPASERCICIYVAVGQKQSTVAQVVKTLTDFGAMDYTVVVSATASDPASLLYIAPYAGCAIGEYFMWQGKDVLIVYDDLSKHAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERACKLSNENGGGSLTALPIIETQANDVSAYIPTNVISITDGQIYLESSLFLSGIKPAINVGLSVSRVGGSAQRKTMRKVAGTLRIDLSQYQELAGFAQFGSELDKESQRQIARGKRMTELLKQNQYAPLKVGEEVLVLYAGVHGYLDSIEVSDVLEYEKQLLAFARAQRPDVLDTLNAANELTKEVEEKVVSTLDEFKTVFKPASQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN13</accession>
    <name>A0A1Y4DN13_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57710">
        <property type="protein sequence ID" value="OUO57710"/>
        <property type="gene ID" value="B5F75_00925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="4"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="95"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="111" mass="12363" checksum="6F84AF8C9711216D" modified="2017-08-30" version="1">MNCIFCGIADGSIKSQLVYEDEDVVAFKDLNPQAPTHLLIIPRKHIARLSEADEKDALLLGKILLVAKKLAQQFDLKDFRLVTNNGKGAGQSVDHLHFHLMAGRRFLWPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNK1</accession>
    <name>A0A1Y4DNK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56981">
        <property type="protein sequence ID" value="OUO56981"/>
        <property type="gene ID" value="B5F75_03800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="229" mass="26181" checksum="44C1B9C408AD61CB" modified="2017-08-30" version="1">MPVNLKTNKIVENLKKGFQDIQTVSQEGNFKLFLKQFIAVLLIFLAFRFLNGKFAEKISNYEGQMDAIRVQQTSEREYQSNKKKLLDLEPQFPDISAKNEWLLSLTLGLFKEANVTPQMEGGQAEDTSNASYTATSLRVNAEMGFDQFANFLAQVENSKDFVKISEFSLEKMKEADKLGMNKISMKFNTIFPKEKIAKSLFKDYDKIMKEREAAAKAAKQQAENKEVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DP92</accession>
    <name>A0A1Y4DP92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_00060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57211">
        <property type="protein sequence ID" value="OUO57211"/>
        <property type="gene ID" value="B5F75_00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="351" mass="39338" checksum="E46809D9063DE8EF" modified="2017-08-30" version="1">MQKDKIVLSGMRPTGKLHLGNFHGALKNWVALQDKYNCYFFVADLHSLTTAYEHTENLAENSRNMLIDWLTAGLDPEKSTIFIQSDVPEVSELNTLLGMITPLGWLLRNPTYKEQIQELLKQKYAGQLDEKSLGEKINSIAGDEEISSFGFLGYPVLMATDILIQQAAYVPVGKDQTAHLEIARDLARRFAEIYGEAVFTEPAPLYTEVARVPGLDGRKMSKSYHNAINLGEDLDSVRKKVMTMFTDPNKKKATDPANPEGCVVYAFHRIYNPNAAKRCEECKAGALGCVACKKELFALMEPEMKAFSERRKLFENDEALLQKIVAIGKDRARANAAKTLATVKKVMRITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPG5</accession>
    <name>A0A1Y4DPG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4424 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57281">
        <property type="protein sequence ID" value="OUO57281"/>
        <property type="gene ID" value="B5F75_00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025538">
        <property type="entry name" value="DUF4424"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14415">
        <property type="entry name" value="DUF4424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4424" evidence="1">
        <location>
            <begin position="25"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="186" mass="21243" checksum="B71DF56BC60C324A" modified="2017-08-30" version="1">MSCTGGSVFLPSKEPGDYEEAEGWTITDREEDLWTKEISYFWVQTFPAGKTVHIRHTYTPSAKTTNTGMPFSSCINPDTWDYQDFVRIPTPTGTDHLWDKLEAQHYVEYILTTANNWQGFIDDFNLLVESPLKSVGCFEGHPFYGEKYFALSRKYFYPERNLSVDFLEKGTIPSSYKPASDPASSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQD4</accession>
    <name>A0A1Y4DQD4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57581">
        <property type="protein sequence ID" value="OUO57581"/>
        <property type="gene ID" value="B5F75_02060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="367" mass="40848" checksum="DA726F48EF10584F" modified="2017-08-30" version="1">MPTGLYIHLPFCRQKCNYCDFASFAGREKQIPAYLAALAREAAQTPVKTFDTLYVGGGTPSLLTEQELERLCQVLTDNFGAIGRFSESTAEANPESLTPGKIALLRGAGFNRLSIGLQSFCDQELKTLGRVHDVKTFLNAYRAARAGGFENINVDLIAGVPGQGLESFLEGLSKLIALRPEHISVYGLQIEEGTPFFARGVVCDQLLMRRMLEETHLRLQAAGYHHYEISNFALPGREAKHNTHYWDNGPYIGLGSAAASYWGGERRQNTPDVQEYIRRMTAGESPVVFREKLTGKVKEGETLMLAFRKLDGVELTPRQEKMFGKEIQKHLQSGLLERAGKKVKLSFEGLFLANEVFCSFVAPFEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA82</accession>
    <name>A0A1Y4DA82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56123">
        <property type="protein sequence ID" value="OUO56123"/>
        <property type="gene ID" value="B5F75_05745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169735" evidence="3">
        <location>
            <begin position="23"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="168" mass="19124" checksum="E68B9BFF5C83C693" modified="2017-08-30" version="1">MRKTILVLGLLAGASLFCAAQAETGKAADRKEDKNRPGVETVIKKSSAPKQTPAEEKKAFEQRRKLIKKLVKQYRKASDEQKPALKEQLSQVVSQSVDAGFAYVKARIAAERENLNNWEKKIQQDEQNIDQIKARRVEELLSGEAERKHKAAQKKWKKQMKKAEKALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAA2</accession>
    <name>A0A1Y4DAA2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphoethanolamine transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05980</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56164">
        <property type="protein sequence ID" value="OUO56164"/>
        <property type="gene ID" value="B5F75_05980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012549">
        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08019">
        <property type="entry name" value="EptA_B_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="EptA_B_N" evidence="9">
        <location>
            <begin position="62"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="8">
        <location>
            <begin position="238"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="551" mass="63561" checksum="1EA1DAF1364DBE24" modified="2017-08-30" version="1">MRKIAAFLHKRFSISSGHLITLLSFYFLLLLNISFWRFIFVHAEPAGLTGYLFMASIPLLIFTLLYLTFSLLTLPYVGKPLLILILLISAGVNYLSYQFGVFIDADMVRNTFETNPGEVKDLITLRSLLWFFVLGVIPSVLLWKTKITFSPFWKELLTRLKRCGLVLLCLILFTPFVYKQYASFGRNNNQVRRLVIPLNYIYATFRYFQIEHQNKRPFTKLDEAAEHVPYPDEEKTVFILILGETARAQNFSLNGYVRETTPLLKKQDIVNFRHVQSAGTATAFSVPAIFSFTPRSRFSPTDAKYTENLLDLLQQTGYEILWKENDNGCKGVCQRVPNVEMDVKDKRFCDGTYCHDEILLEGLEDYLANFQGNNLFIVLHTIGSHGPTYFRRYPEQFKKFTPTCDTEEIQTCTQEQIVNTYDNTILYTDYIVSSVIDILKKFPAYESGLLYVSDHGESLGENGVYLHGIPYAIAPKEQTSVPMVLWMSEVMKKSDHLDYECLKKKAQTGQFSHDNLSHSILSLMEVDSRVYDPKMDFFDECRLDPLPRKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAE8</accession>
    <name>A0A1Y4DAE8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56046">
        <property type="protein sequence ID" value="OUO56046"/>
        <property type="gene ID" value="B5F75_07140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="14094" checksum="CBB807832451B83E" modified="2017-08-30" version="1">MFPDKSSIANFAGIVNSFFSVEKSVFAILVPAFWLFEAGGKRYILICVYISKLFPFRQLFLSVLRFIVRARTRAHKTKKDAPKRNPSSFFVVPVFLFFRCRLYRQEICSKKITPLFYSAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAN0</accession>
    <name>A0A1Y4DAN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysS</name>
        <name evidence="9" type="ORF">B5F75_06510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56263">
        <property type="protein sequence ID" value="OUO56263"/>
        <property type="gene ID" value="B5F75_06510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="177"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="510" mass="57679" checksum="A4BE305B6B1EC28A" modified="2017-08-30" version="1">MSTEHTQHTHNNALDEIIAQRYAEIDEIRKMGIAPYPNRCEKQISCLDAKNAAEGTEAVTAGRLMQLRLMGKAAFAHLRDFSGRVQLYISKDNLGEESYAFFKKHIAVGDFVSVTGHVFVTKTGEKTIKVTKLTLLSKAIRPMPEKYHGLQDTEVRFRKRHLDLIANEDVKDIFIKRAKIITSIRKTLDDKGFLEVETPILNPDAGGAVARPFETYHNALKMPLYMRIALELYHKRLIIGGMDKIYEIGHMFRNEGIDTTHNPEFTMMELYQAYGDVNTMADLFDEILGNAAKAIGIEKIHFRGHEVDLRPPYTRVHIPEKWKEMFGRDIHEVLDGRQFNRAKLEEVAKEQGVKFTADDSDSDIFDELFEGKLLAEYHNPVIAMDYPTAVSPFSKTKPGDPEIVERFEVFVNGQELGNAYTELNDPADQLQRLKDQAAAKAIAKGEDAKNADIVDADYIEAMESGMPPTGGMGIGIDRIVMMLTGQDSIREIILFPTLKKLDEKEEKAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAN7</accession>
    <name>A0A1Y4DAN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysA</name>
        <name evidence="6" type="ORF">B5F75_05710</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56116">
        <property type="protein sequence ID" value="OUO56116"/>
        <property type="gene ID" value="B5F75_05710"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="29"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="34"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="421" mass="45042" checksum="68FBBC20ED7500E0" modified="2017-08-30" version="1">MCFHYQDGELYAEGVSVAALARRVGTPFYCYSTDKLTRNFNAYQQALSDLNATVCYSVKANPNLSVVSAVARLGGGADVVSGGELFVARRAGIAADKIVFSGVGKTRAELEEAVKLGILQINAESAAEVETLNEIALALGKKANLALRVNPDVDALTHVKITTGKKENKFGVPWPEAHELYVKAARLPGIRIAGIAVHIGSQLLDLEPFRLAFTKIAAMVRTLESEGIGIENIDLGGGMGINYNVELPPTCEAYAQVVRETLGGFKKHLIVEPGRSIVGNAGILVTQVIGCKSNGEKNFIIVDAGMNDLIRPALYEAWHTILPVHKTGVAPMIADIVGPICESGDVFAHERIIEPVQAGGLLAIMCAGAYGAAMSSMYNFRPLVPEVLVNGKEFAVVRKRTSYEEMVSAYTVAPWLQGEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAP6</accession>
    <name>A0A1Y4DAP6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56126">
        <property type="protein sequence ID" value="OUO56126"/>
        <property type="gene ID" value="B5F75_05760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012599050" evidence="1">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="15872" checksum="4F56301D66F48CC2" modified="2017-08-30" version="1">MKKLKGIAAALLLLGGCATLEQNNLDWIAIGPDFPPTKAKKVEILGSKGEITRPYGNLGLLRIKNLKPDRDVLKMGVEKGRRFVASKGADAMLIGQYNSAEDGATDPRVTLIIYAIKYVDQLTEEDQKAIEDFKVLGILNERSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAT5</accession>
    <name>A0A1Y4DAT5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56323">
        <property type="protein sequence ID" value="OUO56323"/>
        <property type="gene ID" value="B5F75_06830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="286" mass="31831" checksum="C8A3906858D2F8F0" modified="2017-08-30" version="1">MSLRKKTPKKQTTPGARRRFLLPLSFLLLSFLLMILPLEGFVSSVKAVLAYVFIPQVRLAHGTAKYAENVHQTVRELLDAHRENRELKQEIEMTKLLASQAEAILDENGRLTEILRLNPARRWTGVWAKVAYREPTQWNTVIIDKGSRDGIRERSAVISMQEGKEGLAGVVVEVTENTSKVLLVRDEDFSAAVYLERGQEEGLLVGNGPRPVRIKYIPLLTHVEKGDKVFTASTSSIFPAGILVGEVSGVREDESFQTALTVNVDPLVSSAAVKEVFVILDNEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAW1</accession>
    <name>A0A1Y4DAW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="12" type="ORF">B5F75_06890</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56334">
        <property type="protein sequence ID" value="OUO56334"/>
        <property type="gene ID" value="B5F75_06890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="31"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="201" mass="21080" checksum="5E4B35E9A214D96C" modified="2017-08-30" version="1">MSNETLVKSDNRKEAKGKRAEFQKARPLSEGKTTVIHVARTAKVVKGGKRFGFRALVVVGNGQGKVGVAIGKANQVQLAIAKAESHARKHMITFPIVGETIPHEVIGKFGAASVWMKPAAPGTGVIAGSGARLLFEAAGIKDVLAKSLGSSNPCNLVYATMEAFKQLKSKETVNVLRGKAEKAPAAEAPKAEEPAEAAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAY2</accession>
    <name>A0A1Y4DAY2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56354">
        <property type="protein sequence ID" value="OUO56354"/>
        <property type="gene ID" value="B5F75_06995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12136" checksum="BE937C415815D5FA" modified="2017-08-30" version="1">MIVAGLFFAGCAANTPVKNTVVNPKAKNYTEAVESAAKTCKVDADCTSVKRGCCLCNGYAPVNKEAAAALQPMWEKECAMAACTLQMCYVEINTSCQNGVCVGTPKPMEDYMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBF6</accession>
    <name>A0A1Y4DBF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56205">
        <property type="protein sequence ID" value="OUO56205"/>
        <property type="gene ID" value="B5F75_06195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="165" mass="18257" checksum="F6DD16B4DDC1DC99" modified="2017-08-30" version="1">MAAIALPQYEKAVAKAEFVQTRDIMYEIYRARQLYLMEGGSTSDQDLNNYPDLQLPAGATLGCVLGKKEDGSCVNGDSKIMMGNKSLIATGTAHAYKYYKKGPYYIRLMLPVHWAGESGLDKKFQIKCNAMDNTDEKSKNLCKILSGGKEPTTCSYVSGDCWLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL1</accession>
    <name>A0A1Y4DBL1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMPK1_CBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56527">
        <property type="protein sequence ID" value="OUO56527"/>
        <property type="gene ID" value="B5F75_04860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="AMPK1_CBM" evidence="3">
        <location>
            <begin position="136"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="207" mass="23039" checksum="25278DF630F15822" modified="2017-08-30" version="1">MENENLDLDIKPAGNKDLWLFLIIVDIIFLCVFGFFLYKHFSARLFDAPAAAATVEQTEVVEVPEISETDVVAGTEAIVVESVAAAPVSNEELETKPAPVKEPEVKPAEQTQPAAAQEKKESIVVKVNPKSKYRRVTFRWFGEGNKVSVVSGFTMAKPKPLKKRGDYWETTLSIAPGTYKFLYVVDGKNKLDPYSEEKDGRSLLVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBQ3</accession>
    <name>A0A1Y4DBQ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CYTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56577">
        <property type="protein sequence ID" value="OUO56577"/>
        <property type="gene ID" value="B5F75_05125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050355">
        <property type="term" value="F:triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039013">
        <property type="entry name" value="YgiF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39569">
        <property type="entry name" value="PTHR39569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="210" mass="23967" checksum="E2486ECB38F030CE" modified="2017-08-30" version="1">MKNMETEFKWDANVPRAFARMRRAVEQAAGQASPRGAVQLAICDVYLDTPDSAFEKQQIAFRVRCCAGQWQATFKTRTEVKNGKAVRREETLELPGVKNLKEALSFLNQKKRWKNLPLQQLRPLFKLTNRRTVQLLSFPSLEAELAFDQCTLYVAGRKVQMKEIELELKKGKASALETLARQLTQQSGLSYMRVSKVKTACGLLKLWGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBS0</accession>
    <name>A0A1Y4DBS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_04805</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56516">
        <property type="protein sequence ID" value="OUO56516"/>
        <property type="gene ID" value="B5F75_04805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="476" mass="52401" checksum="8A8C0B62A32A3DFD" modified="2017-08-30" version="1">MLFYFQKLIYYNKSMEPINWREVYARTKEFIKTSLKKYSVFLLRLTPHQNIAQAVLSYTLLGWILLSLPFMNTTDVSFIDNLFTSASAVSTTGLSSVNFAESYTFLGKLVVLLLIQIGGVGYMTFSSFLFLSFSQHHRLRKSQQEALAAEVSLPNTLKLSDFLWAAIVFTVIAESIGAVFLFNYFRHHSYGLFDAAWYSIFHSVSAFCTAGFSLWSNGLENFADSKTVNIVISALSLAGAIGFIVVTDVFNFIRRKTKEITYTTKIIIVITACLVLFGTATLFITTPGITLLEAFFQAVTAMTTAGYNTVNIGGLSACSLLILIFLMSIGGSPSGTAGGIKTTAFASVLAITYNRLRLNTRVEFLGRRIPLVRLYAATSTLMIYIVSLFTSIFLLTWTEDLPFLSLAFESASALGTAGLSTGVTMELSVLGKLIIIFTMLVGRIGVVTFGMALLGTDEDDNDEQDEKPAEREDVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBU8</accession>
    <name>A0A1Y4DBU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">efp</name>
        <name evidence="11" type="ORF">B5F75_04960</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56546">
        <property type="protein sequence ID" value="OUO56546"/>
        <property type="gene ID" value="B5F75_04960"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="68"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="188" mass="21248" checksum="32842288BC96464D" modified="2017-08-30" version="1">MLSTTEFREGLIFEDENGQLVEIIEFQHHRKSQARAVVRVKLRNINTGAVIETAYRPEDKFKEVEVEKRPFQYLYTNGDMATFMNTETYDQVEVEVKKLGDLTKYLKDNMDAIGIYINDKLFNVELPIKVPLKIASTVPGVKGDTVANTTKEATLETGAVIKVPLFINEGDTVLVDTRTGNYVERVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBV0</accession>
    <name>A0A1Y4DBV0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ORF">B5F75_05345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56617">
        <property type="protein sequence ID" value="OUO56617"/>
        <property type="gene ID" value="B5F75_05345"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="345" mass="39209" checksum="896AAF14467F27EE" modified="2017-08-30" version="1">MAFERFKKLNLDPLIAKQPATPRDSARQMVLHRDTHTIEHRIFRDIHEYFNPGDALVINNTKVFPAKLFAHKPTGGKVEVLLVRPMQKPNVWAVLTRDYKEGITLDFGDGLRAKATGKTENNEAVLEFNQEDILPFCNTHGLMPLPQYIEKARKHDGMTPSIATDKDRYQTVYAKYTGSIAAPTAGFHFTPELLQKLKDKGVHICYITLHVGWGTFKPLRGEPEQHHMLAELGEVSPETADTLNAVRANGKRVFSCGTTSTRTLETFTDENHITHPGKKWTDLFIYPGYKFKGIDCLITNFHFPDSTPLCMTSAFAGEDFIYEAYLQAVEKKYRFYSFGDSMMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW9</accession>
    <name>A0A1Y4DBW9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56355">
        <property type="protein sequence ID" value="OUO56355"/>
        <property type="gene ID" value="B5F75_07000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="86" mass="10124" checksum="7561FB2058EF785D" modified="2017-08-30" version="1">MNEVFAHYVERVHVACNADEDCVAVLKSCQYPQWGYTAINRRELEDFNRVREADWYTRCDKQPDTSAVKTACRNHRCVLAKEEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBZ9</accession>
    <name>A0A1Y4DBZ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56586">
        <property type="protein sequence ID" value="OUO56586"/>
        <property type="gene ID" value="B5F75_05175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="15817" checksum="ABF5ECF0DFA247DB" modified="2017-08-30" version="1">MPELHILIFQFVMSVISASIIPAQGELIMFALLASGKYTDWLLLTVACGGTFLGVSINWVLGRYLSKFQNEKWFPVKGAYIEKAKALFDKHGRAALLLAGIPLIGDPITIVAGALKVNFGFYLVTAGLSKCARYGLVFLIYMGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC10</accession>
    <name>A0A1Y4DC10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56677">
        <property type="protein sequence ID" value="OUO56677"/>
        <property type="gene ID" value="B5F75_04385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34980">
        <property type="entry name" value="PTHR34980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="112" mass="13067" checksum="C264AA7526137A43" modified="2017-08-30" version="1">MTYYWDVLKNHYVDFKGCATRKTYWLFVLFNFIVFFILSVILSFFGDAGDILYFLCTFAVLLPSLAILVRRLHDTNRSGWWVLISLLPFIGTLILLIFLVLPSTEGENRFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC25</accession>
    <name>A0A1Y4DC25_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56122">
        <property type="protein sequence ID" value="OUO56122"/>
        <property type="gene ID" value="B5F75_05740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045739">
        <property type="entry name" value="ACT_dom_pair"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19571">
        <property type="entry name" value="ACT_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="74"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="136" mass="14659" checksum="E392DD9B4686BEE1" modified="2017-08-30" version="1">MAISVVKQYSVFLINEPGALKNFAELFVRENVDVIAISQDVRYDAAVVRLAIKYEQEISHALTKAGFTSVKTDAICLDAPNRVGLIRDIGSVLSNNGINITTIYGTAGAGTDSRWIIVVNDITKALNALEASGLFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC96</accession>
    <name>A0A1Y4DC96_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide heptosyltransferase II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56784">
        <property type="protein sequence ID" value="OUO56784"/>
        <property type="gene ID" value="B5F75_02770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011910">
        <property type="entry name" value="RfaF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02195">
        <property type="entry name" value="heptsyl_trn_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="524" mass="59167" checksum="6200224E34C57218" modified="2017-08-30" version="1">MNENEPKILVVRLSSLGDIVLSSPVYKNLKAKWPHAHITLMVKPQFAQVLAGHPDIDEIMVAKKGLWANIRQIRAGHYTHYLDLHSTLKSILMGFFSRIPNRIRYDKNSVARRMLVKFHKNSPVLEKHTLDKYLEALKAWDIDIKYKAPKLGDWAYQHANMTGKKVNKIGIFQTSFIGDSVLTTPLIQKTAKLFPETKIVVITRPQTEDIFRPMKEVSEIILNDKRGWNKIFGVWKTAKAIKNSGIDILLVPHRSFRSALIAWLSRVPVRIGFTSSEGWFFYTKTVPFSWMIHDAERNLSLLQGIVKEKFTAEKLSMRYAPSAEENVARLMKDFNLEGQTLVGIHAGSAWPTKCWPMEYFVQLISRLQTELGVKAVLVGGGAKDADLGEKICQLSKGHAANLCGKTSLADLMALMKHFKLFITNDSGPMHIATAFDVPTLAIFGPTTRELGFFPYGEGHRVMEVKDLPCRPCALHGGRKCPLGHFKCMKDILPDRVFQNAKEMLEENHSLPAQTEKKAEPATAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCC7</accession>
    <name>A0A1Y4DCC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56814">
        <property type="protein sequence ID" value="OUO56814"/>
        <property type="gene ID" value="B5F75_02925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012779736" evidence="1">
        <location>
            <begin position="21"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="445" mass="51075" checksum="4CB210550BA469CC" modified="2017-08-30" version="1">MKKIIISCLFILSCYVGLHAQSTGEILTFPPSPEKGFFWGYALYLPKTMNTSHKLPILLIMTDCGVTDSIQETEEKTLFRLRHELSEYPIADELGVPLVMPIVQRPEDFYTHALSRAVFTSQEEPFKRLDLQVLNMLRDARQQLSKRHIHTKNKFLVTGFSAAGVFAWRWAMLHPEYVLALATGGALYHMLPIEELNAERLIYPVGVADMQEYTGRKFNKKAWSKIPILSTNGEMDDNDTFLYEECFAEKVERPVLQKVLPGKDVFERRAQSLQLLAKLAPNVQTHLYPWLGHEPVTQDVIAFFRQYVPAPAFQLTDTSDRKPDFPVNIVKAMWGNDPQIPEIYKQWIAENDFVLLTSASHPYWVYNQYAEIIISCNGEKIIQSQKAGSFSDGEKTFISFKFTPSDWENLIKKKGCKFSIHALHPQFLHIPDTLTVPPFNSQNLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCF2</accession>
    <name>A0A1Y4DCF2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56777">
        <property type="protein sequence ID" value="OUO56777"/>
        <property type="gene ID" value="B5F75_02735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010539">
        <property type="entry name" value="UCP009160"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41282">
        <property type="entry name" value="PTHR41282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12811">
        <property type="entry name" value="BaxI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009160">
        <property type="entry name" value="UCP009160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="26313" checksum="9824C25022092FD8" modified="2017-08-30" version="1">MNNPMLNENAFKRAQARALSDTGVMTLQGTINKTFLLLFLCVVGGMITWTHYQSWAGATGIIAIVAFVVALITSFKPTAAPITAPIYAFLEGLFLGVISAMYNAQFQGIVFNAVAITVLVFFVMLFVYRTGIIRVTRGLAVGIFSATAAIALLYIGSFLLSLFGVSTAYLTSNSPLAIGISVVICAVAAFNFLLDFNFIDAMTSRYQAPKHMEWYAGFGLLVTLVWLYIEILQLLAKMQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCL0</accession>
    <name>A0A1Y4DCL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ruvB</name>
        <name evidence="8" type="ORF">B5F75_05335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56615">
        <property type="protein sequence ID" value="OUO56615"/>
        <property type="gene ID" value="B5F75_05335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="55"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="340" mass="37141" checksum="37A141DF5E368480" modified="2017-08-30" version="1">MSNQNEILDVSQLPEESAGLEAALRPTTLDEFVGQDKLKENLRIFIAAAKSRKEALDHCLFYAPPGLGKTTLANILAKEMGVNIKVTSGPVLARPGDLAAMLTTELSDGDILFIDEIHRLNPAVEEALYPAMEDFTFFINTGKGAGSTTLKLAVPRFTLVGATTRSGLLTGPLRDRFGIVFNLGFYEVPEITDILERSARLLAIQADREGLTELAKRSRGTPRIANRLLRRARDFAQVKGNGVITREIAKTAMDSLDIDEEGLDSVDKRILEALIDRFSGGPVGVDNLAIAVSEAVDTLTDVIEPFLIKAGFIARTPRGRVATRKAYDHLGRKQHTDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM6</accession>
    <name>A0A1Y4DCM6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <shortName evidence="6">RNase P protein</shortName>
            <shortName evidence="6">RNaseP protein</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnpA</name>
        <name evidence="7" type="ORF">B5F75_03180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56863">
        <property type="protein sequence ID" value="OUO56863"/>
        <property type="gene ID" value="B5F75_03180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="125" mass="14150" checksum="A02F796A07FB1724" modified="2017-08-30" version="1">MPSYGLPRSSRLHLKKDFQQVIHGGAKLQYNGVILWWRSGPENTRPARFAVVVSRKLGPAVVRNRAKRLLREAFRLNRKNIKEGTDLVFSPRESEKITHVHAAQEALKTLCGKAALLKHSSENKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ1</accession>
    <name>A0A1Y4DCQ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="8">CMK</shortName>
            <ecNumber evidence="2 8">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ispE</name>
        <name evidence="12" type="ORF">B5F75_05440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56635">
        <property type="protein sequence ID" value="OUO56635"/>
        <property type="gene ID" value="B5F75_05440"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="10">
        <location>
            <begin position="94"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="11">
        <location>
            <begin position="226"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="297"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="321" mass="35224" checksum="F5F71C22E326FBC6" modified="2017-08-30" version="1">MKTTRFCPAKVNLFLEVTGKRPDGYHELATLFAKINFGDTLVLEAEPAEQTEISLQLTGPVGPMLRADESNLACRAAKAFLDYFHLRAKINMQLEKHTPTGAGLGGGSSDAAGVLLALCELFKKDKNLLLNTAAKLGADVPVFMYEETFLKGEGIGEKLTPVPAPGPLPWLVLVYPNTVVPTKGVFARLKLPSQEEILTNRSNLDKLITDIRCAYPLAGWKHLLFNRLEDCVVPFTNSVRNVLRDLRKTNTDAVLMSGSGSTVFALVETEKDAKDLVNKLQNEERIVFSTTFHRSLKDENNGNKDTSYGGGSPKSVRQCNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCT5</accession>
    <name>A0A1Y4DCT5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56933">
        <property type="protein sequence ID" value="OUO56933"/>
        <property type="gene ID" value="B5F75_03560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="311"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="548"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="343"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="615" mass="68847" checksum="1B17ACAC6B93B9A4" modified="2017-08-30" version="1">MIDIKDLSFHFGLRTLFEDTSVMIQDGQKVGLVGPNGCGKSTLFKLIEGKFSPDGGRIDISRGTKIASVAQDIEDPSVALLDYVLASDKELSALQKELQDPNISGERMAEVFDRLEFLGAHSAEARASAILSGLGFVNEDFRRPLKEFSGGWQVRANVAACLYAPSNCLLLDEPTNHLDLETAMWLENYLVRLDKTIFIISHDRHILNRLCDKIIHVEDAQLKLYNGNYDTYERTRAAAIEGARLAAAKHERVVAHLQSFVDRFRYKATKAKQAQSRIKMIEKLGDAPAIPKDPEVHFQFPSPERLQNSLITIENGVAGYDDKPVLQNLNLRIEPDDRIALLGANGNGKSTLAKILSHRLLLMSGKMTMAKKMKIAYFSQHQTEELDVEKTPYEQLSAVMPLATETQIRAQLGAFGLNKAKSDTEIGKLSGGEKSRLLLALITKDAPHLLILDEPTNHLDIQSRQALLEALNDYEGAVVLITHDLHVIEYTCDTLWIVRHGTCQTFTGDLEDYKAQLLKNNDRNDLASDKMTSKEAQRRAAAQRRARVAPLKKEIRALDEKIEKLTARKKALEEQLTAQYSADGSIELALLNDQLQKAEDEWMRLSEEYEQACAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCX1</accession>
    <name>A0A1Y4DCX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57014">
        <property type="protein sequence ID" value="OUO57014"/>
        <property type="gene ID" value="B5F75_03990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="71" mass="8187" checksum="5D3195C77DBB7A85" modified="2017-08-30" version="1">MWTALMLCLAGVGAVYGLCRLSGALARQQERLRHVQQERKEDEQMDEIMRRVGRINDADLPKFLRAEADKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCX3</accession>
    <name>A0A1Y4DCX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56462">
        <property type="protein sequence ID" value="OUO56462"/>
        <property type="gene ID" value="B5F75_04520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012147286" evidence="2">
        <location>
            <begin position="20"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="212" mass="21334" checksum="7DC7F9F565D6B6C5" modified="2017-08-30" version="1">MKYFLCIFSVLVLFSPAWGQRPVTKVAVSRPTTAVAVSRPETAVNVVRPTTSVGVVRPNTSVTLSRPTTNVAVSRPTTQQAVYKPATVIFTSHPSTAGTSSSSASGAASFGKKGAVSSAQAQTSMSNYKPPQAKDFKALTAASAVGGGAGGLGNKTNQAEKDAAAAAFQPSQAKDPSAVSAQSVMSSGGASTGGQSLLNLLKQKAAGRSGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD07</accession>
    <name>A0A1Y4DD07_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ORF">B5F75_04725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56502">
        <property type="protein sequence ID" value="OUO56502"/>
        <property type="gene ID" value="B5F75_04725"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="278" mass="30266" checksum="8A7ED869A1C51AC1" modified="2017-08-30" version="1">MQFTKYTGLGNDFIVLDGETARGVQHPGELALRMCNRHFGVGADGLVLLLPSEKADMRMQIINSDGSEAEMCGNASRCVALHLYRRGIVPKRQITLETLAGLIHTEIMDEASSRVRVDMGMPRLTRGEIPMTGLAHERAVNVALRACGTEFCGTAVSMGNPHFVIFVENAEKIPLEVWGPALETNEAFPRKTNVEFVQILNNATIRMRVWERGAGVTQACGTGACAAVAACILNHKTNDYVTVKLDGGELLIEWPAGKNIFMTGPATEVFTGEYKGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD53</accession>
    <name>A0A1Y4DD53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56956">
        <property type="protein sequence ID" value="OUO56956"/>
        <property type="gene ID" value="B5F75_03675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="238"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="580" mass="66038" checksum="5AFC1D960683E731" modified="2017-08-30" version="1">MSFIQKYIFSPFKNDWKLLLVLSLPAVLLCLFGLGQLGRLTPVNFLAAESVKLVCEFLFLGALLSLLHLLGVKNKWLAGLLAFIYYLTLTADLILLWYFKERFGAKYLDTMEGGDYNFLTDWRVLSYFAVLAIFCGFAVKRFFRAAPRKTAFNRLLVCVAGLALLGAANPLKLLPAPNDFYTSYLITPSPVYTLNAVLTPRPQARLNQPLTPELEKLAQEYNVFSARNTGVGKKYTRVILIASESLSNKYLHRFNPNIPLQASRPLDELMEKYPSASLQHVTLSTLYGLTVIFTSHPFAELAFANGYPVSFVKELKKHGYKTAFLRGADETYMDENVLFHQAGFDEVIGATYFETRPDYKDYIDWWGLTDRKLFDYAAEYLQEHKQEPLFMTLLTVDSHVPLGRLDYLGQEYEEIDAEFYDVPTLPRAFARFGQDVSRFLKQLDEKGLFDQNTLVLIMPDHPSYSNTPTNKLFKPYRPEYDNLPFVIVTRTPIEKPLAANPLVSQLDIAPTLMDLLNLPQPKGFFGHSLFDAAAQRSVFDIKEDYAVVTTEKSSRVVPLNSKKETDQPLLNLIRSFPPED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD84</accession>
    <name>A0A1Y4DD84_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56592">
        <property type="protein sequence ID" value="OUO56592"/>
        <property type="gene ID" value="B5F75_05210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="166" mass="17882" checksum="2A27D4F0D0618217" modified="2017-08-30" version="1">MQNKGFTLIELLVVVLIIGILSSVALPQYEKAVVKARAANAYQILKSINTAEQLANMDNGTKGQRYPFEELSVAFTDKNGNTATGYSFMAKDYTFFIQGTREQNKREPATAVLAGTSIYLSINNGRRACGVVDPSNADAVSLCRTIVGSNTVSSAMCVSGTTCYME</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDN7</accession>
    <name>A0A1Y4DDN7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-dehydro-3-deoxyphosphooctonate aldolase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3-deoxy-D-manno-octulosonic acid 8-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">KDO-8-phosphate synthase</fullName>
            <shortName evidence="6">KDO 8-P synthase</shortName>
            <shortName evidence="6">KDOPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phospho-2-dehydro-3-deoxyoctonate aldolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">kdsA</name>
        <name evidence="8" type="ORF">B5F75_03820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the KdsA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56985">
        <property type="protein sequence ID" value="OUO56985"/>
        <property type="gene ID" value="B5F75_03820"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019294">
        <property type="term" value="P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00056">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="12"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="277" mass="30057" checksum="AD91BB60E1E50B29" modified="2017-08-30" version="1">MYMQKTIKIGNYKISNNLPLVFMAGTCVIESEKHYLDTAKKLKAILAKTKHPFILKASFDKANRTSVDAYRGPGLAKGLEILTKAKALTGLPLVVDVHEPWQAEEVAQVADILQIPAFLCRQTDLVLACADTGRAVNVKKGQFLAPGAMEQVIKKIESRGNHKILLTERGASFGYGDLVVDMRSLEIMKQFGYPVIFDATHSVQKPGALGCATGGNRQLAPVLAKAATALGIAGVFFEAHPDPDHALSDGPNSLNLEMTAQMVRQLCAIDQVVKKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX0</accession>
    <name>A0A1Y4DDX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57236">
        <property type="protein sequence ID" value="OUO57236"/>
        <property type="gene ID" value="B5F75_00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="213" mass="24176" checksum="87140495A9D5679B" modified="2017-08-30" version="1">MPDKNRNCYNNYMEPNYPNEGMRQLLDGYRHFFKGNSPRKGFCALHAEQIAHTQNPHSMVISCFDSRVCPEAIFATNDGHICVHRNMLNQVDTRDVSMMASLQFAVESLRVQNIVVLGHSNCNAVAKLKMLDKLPAAISAWLGGGKYRGDSYEQAIKNNVLDQLARLREIAFVQQALAQGKLNLEGMVFHIDTGRLERFDARQNGWNFVETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDZ4</accession>
    <name>A0A1Y4DDZ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMPK1_CBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57327">
        <property type="protein sequence ID" value="OUO57327"/>
        <property type="gene ID" value="B5F75_00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMPK1_CBM" evidence="1">
        <location>
            <begin position="80"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="17363" checksum="7FCA116AA3CC8CBA" modified="2017-08-30" version="1">MPKIKRPGALFVLFVLLIAIVLTWFFAASEDYYDYAADTIESSASVAPLNKESLLARMQPVRHNYDTEVKYRKFYITAPGAKKVELLADFNRWGKDPIVLKPYRKGYFETSVALTGGEYKYVFSVDGKEVLDPTNLDRREVDGHEICIKTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDZ5</accession>
    <name>A0A1Y4DDZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="8" type="ORF">B5F75_03230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56872">
        <property type="protein sequence ID" value="OUO56872"/>
        <property type="gene ID" value="B5F75_03230"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="53"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="297" mass="32366" checksum="F5C50F8211791A71" modified="2017-08-30" version="1">MTTPMPQWLKDLVGRNKAALRSSAALHAQQSIDQHLLHTVCHAARCPNRGECFNCGDATFMVLGDICTRGCRFCAVTKARPLPPDENEPERVAQAVKEWGIRYAVLTMPTRDDLNDGGAAHFARVIRAIKTLTPQVKVEPLISDLRGDVSALQTVLQARPDVLAHNVETVPDLYAAVRIGADYKQTLTLLENSKKLAPHIFTKTGFMVGLGESDGQIRALMRDLRAAGVDLLTIGQYLTPSAAHYPVARYPEPAEYRAWEEYALSIGFKGVASGPLVRSSYRAGALYARAVSGGVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE43</accession>
    <name>A0A1Y4DE43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57393">
        <property type="protein sequence ID" value="OUO57393"/>
        <property type="gene ID" value="B5F75_01060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004740">
        <property type="entry name" value="Nuc_H_symport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03825">
        <property type="entry name" value="Nuc_H_symport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="211"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="438" mass="47739" checksum="44C3C646783FBD06" modified="2017-08-30" version="1">MNIKIRLTVMNFLQFAVWGAYLTSMGTFLAGAGLAEKIGWFYAAQGFVSLFMPAIIGIVADRWVPAQKLLGICHFLAAAGMAAAAYFGSLPQVSFAAVFGMYLFSVAFYMPTIALSNSVAYTVLRQHNFNTVTSFPPIRVFGTVGFICAMLTSNFTGFQNTYMQWYFSGILGLVLGLYCFTLPNCPTCETKAKTLAEALGLKAFALFKEKKMAIFFIFSMLLGMSLQVTNAYANPFINGFNSLEGFAGSWGANNANALISLSQMSETLCILLIPFFLKRFGIKKVMLISMFAWVLRFGFFGIGNPSTASGIVLLVLSMIVYGVAFDFFNVSGSLYVDKETDPAIRSSAQGVFMLMTNGFGAMIGTLGAQWVINKLVNVHINAYTAANGFLPAGSVYPADVSKAIMNGWSESWFVFAGFSLVVAILFAFVFKYKHVPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE51</accession>
    <name>A0A1Y4DE51_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0597 protein B5F75_01120</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0597 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57404">
        <property type="protein sequence ID" value="OUO57404"/>
        <property type="gene ID" value="B5F75_01120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01845">
        <property type="entry name" value="UPF0597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021144">
        <property type="entry name" value="UPF0597"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30501">
        <property type="entry name" value="PTHR30501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006054">
        <property type="entry name" value="UCP006054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_alpha" evidence="2">
        <location>
            <begin position="153"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="429" mass="45634" checksum="55F6D6CBEFD8DAB1" modified="2017-08-30" version="1">MNILKEVLKYQVYPAMGCTEPVSVALCAAYAAKELGEPIARADFKLDAGTYKNGMGVRIPNTDGEKGNLLAGAMGIVLAQPELNMQILGGADKQTVAKAKELLQAHRVHMEVAPDVHGFYIEAELTGLSGKTAKCIIAGSHTEVVFLAQGQNVKINQLPLENNTQQANEFKASLKKATLKELLDAADNADEEDLAYIKKGVEMNLKAAELGQALQKVGFYIKELVRKKLLQMDLISSTKILTACAADARMDGQAVAVMSSGESGNQGVVTILVPWKVGKEMEVDEKTILKSIALSHLLNGYVKVFTGELAPICGCAIAAGVGASAAIVYQQRGKCVPAVTLSINNIISDIGGMLCDGAKSGCALKVVSSTDAAIRAAYMAIHDYGITEVEGFVGKTAEETIRNLGSISSIGMRQVDPMIVDIMQEKCRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE60</accession>
    <name>A0A1Y4DE60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57413">
        <property type="protein sequence ID" value="OUO57413"/>
        <property type="gene ID" value="B5F75_01175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033175">
        <property type="entry name" value="PSD-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35809">
        <property type="entry name" value="PTHR35809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="222" mass="24543" checksum="A7ACBED245F4CBAF" modified="2017-08-30" version="1">MLEDINRTLSKCLSWVGTVLPLGIKFFAVAVAAAAILLFFDLRTLGVLCLLAGCFCAYFFRDPKRETVFADDEIACPADGTVLSIKTEDDPNSVVIRIFLSIFDVHIQRSTVNGRTGEIFYNKGTFLFANNPAADKNERNLIQLFRNGNPAQFAHVEQITGAIARRIECWVKPQQDIKIGGHLGLVRFGSQVAVYLPKNAVRVLVKEGQKVQGGITVLGLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE65</accession>
    <name>A0A1Y4DE65_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57414">
        <property type="protein sequence ID" value="OUO57414"/>
        <property type="gene ID" value="B5F75_01180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="264" mass="29279" checksum="68DAE3C11D46BD68" modified="2017-08-30" version="1">MQDENKETKVVDRLKHTGALTAPSLFTLGNLSCGFFSILASARGNFAQAGWLILAAAVFDMFDGRIARLLDAESDFGVEMDSLADAVSFCAAPAFLMYFFVLHAQPLWGAPIACVYTCFGVLRLAKFNTMAHAGQGSKKYFSGLPVPAPAALLASFAISYSIMEGEMGGRNIHLLTLYLPHLYNFVWFAMLILSLLMVSNIPYAAFKAKREKRLSVWTLLLIVFLVVMLIRFPQDVIFIVFSLYVIFGLLAVLYRAFRGIKVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA1</accession>
    <name>A0A1Y4DEA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57215">
        <property type="protein sequence ID" value="OUO57215"/>
        <property type="gene ID" value="B5F75_00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="308" mass="33507" checksum="83020BA7D373ED90" modified="2017-08-30" version="1">MNKNDPVIRVKNLVVAFGSFHAVDGVSFDVQRGEIFGFLGANGAGKTTTIRTICGILNPSSGTVEVDGKDVSSSTAVLKPRIGYMSQKFTLYPDLTVRENLHFAGSLYAMSPQAIAQRSHKLMEFIGLSEDLPDPVSHLSGGVKQMVALASSLLHDPELVFLDEPTAGTSPKTRASFWALIRRLAQLGKTIFVTTHYMDEAEYCGRIALMERGKIVAMGTPGELKKEFFPVKPLELSFTKPVEQPLRAALEKAGIASAVFGSRLRVRAPDRAAFEQAAAPFRDGFFARETEPTLEDVFLQAVSGRKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB7</accession>
    <name>A0A1Y4DEB7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01605</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57494">
        <property type="protein sequence ID" value="OUO57494"/>
        <property type="gene ID" value="B5F75_01605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="344"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="484"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="741" mass="84059" checksum="6A1072AB0D0000F1" modified="2017-08-30" version="1">MQRISFRLFIFLFMAAAAVIVAGVLLYWQQVSGILERDVKSHVAAASEEAASDFNRLIQNDQQVLESIAITVEDTYPWADTVNLTEFLRRQTQHNYFKLLGVITEGGDVFLSSERSFSPVFITDVLARTLEEGNYLSVRQADPADGKDVLVQAVLLKKQGRPVGALFALQEPGRYRPLLALSAMGNKGYSLVIERNGEPVLGYRSPRFSNAFEELSGVEFDGEMTPAALRQAVREGKHFMVGFRGPNGHRFLHFIPLQVNDWYMVSALPTTYVEQQARQLTYLSLILFLSIFVIFCALIFYTLHMRAYSNRQLFATAFVDQLTGADNFNRMCEQFPEKLAGLNGKAALVIFDINKFKVINDLHGYERGNQVLQRVARVLRENISPEECFCRSTADNFILLLKYTDRKSFRSRIHALATQLRRDCTVEDSCLMIDVAFGVYEVTEDIPFYIMLDRAHLALENAKKMSFDKCQFYDEADRKRIVAEKQIENTMEAALDHGDFSVFLQPKCDFATGQMRGAEALVRWNQAEQGLVKPDDFIPIFEKNGFILRLDMFILEEVARLLAAWKVKGLNRVPVAVNFSRLHLNDTRYIPQMLRVVDKYDVPHEMIEVELTESVIFNNLERAQNVINRLHRLGFSVAMDDFGSGYSSLNVLKSLQFDSIKLDKEFLSGFENNPHAHQVIEGAVAMIKSLGIQVVAEGVETSEQADFLRHTGCDLAQGYFFSRPLPAAQFETLLSKTTSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEE3</accession>
    <name>A0A1Y4DEE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57514">
        <property type="protein sequence ID" value="OUO57514"/>
        <property type="gene ID" value="B5F75_01710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="169" mass="18979" checksum="C87C21024E4885E7" modified="2017-08-30" version="1">MAKIYQKSFPGAKNAGFTLIELLVVVLIIGILAAVAVPQYERAVLKSRMMKLLPVTKDIKNAEELYYLANGKYTENFNDLDITPFGTISTANPSYIGWDKNQCALFHSPFGWVWCTMPMNTPYATCGWKVWLDHSNKPGKIECVYGNYNVQDPKCEEVCKTTGFDYGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF2</accession>
    <name>A0A1Y4DEF2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="8" type="ORF">B5F75_00400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57275">
        <property type="protein sequence ID" value="OUO57275"/>
        <property type="gene ID" value="B5F75_00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="83"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="20"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="94"/>
            <end position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="212" mass="22817" checksum="3A8DB8EAF9071C56" modified="2017-08-30" version="1">MSIFHHKKEISIQTIRRLPQYLRIFYNLHAYGRELVSSTALAEETQLLPIVIKKDLQAVGAPSKLRAGFKVAGTIAVIEKFLGWNNLNKAFLVGVGHLGAALLGFDGFKNHGLEIVAAFDTHPEKVGNSVHGVQVYHTAQLAGIIEKQNLKIAILTVPAAAAQGITDTLVAAGIKAIWNFAPVNLTVPPGVVVQKEDISSGLAELCAKLKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG9</accession>
    <name>A0A1Y4DEG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57295">
        <property type="protein sequence ID" value="OUO57295"/>
        <property type="gene ID" value="B5F75_00510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="558" mass="61209" checksum="35BFB0C18AD60203" modified="2017-08-30" version="1">MMKLMNTQANPMAEGIIREGEIKLEGLDFNTKFWAKDPTLWKHDKEHMEFIVKFLGWQKVYDWTLERIDEVLAFANDVKQNFKHCVIMGMGGSSLAPEVFRTVFGKQDGWPELIVLDTTNPDWIGAARARINPAQTLFIFASKSGGTVEPSSQFAYFLDEVKKAGVKEPGQNFAAITDPGTGLVALAKKHNFRKVFLNPADIGGRFSALSMFGIVPAAIMGVDVKRLLTVAKEEAATFGPDAPVKDNAAVKLGAFMGACNVNHNQDKLTLLTPKDFATFGLWAEQLVAESTGKEGKGIVPVAGETLTPNFDYREDRLFVHLSTGSEDDKRVSAIAKDLAERGYPILTIFMKDIYQLGAMFLLWEIATAAAGAILGIDPFDQPNVQEAKTLTKNILAKLEAGDIPAEVSAPILVSADIADEVKLDTLSQDLYSLLESNDYVAILPYVYPSEDVEKALLALRDKIMARTKRAVLFGFGPRYLHSTGQLHKGGGNNGVFLILSADPAKDIKIPGQHYTFGQLCNAQALGDFQALQAKGRRVIKLHLTQPLLESIKKISSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN9</accession>
    <name>A0A1Y4DEN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">B5F75_06115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56189">
        <property type="protein sequence ID" value="OUO56189"/>
        <property type="gene ID" value="B5F75_06115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="3"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="434" mass="46689" checksum="A92B52429E87F2D2" modified="2017-08-30" version="1">MTVAQQAARAKEASYVLAALPPETKDRALNAMACALRVHADEILAANRLDLQQARLAVEAGHMKPALYERLKLTREKLETVIKGVEELVELPDPVGRVLAATELDEGLSLYKISCPIGLIGVIFEARPDVVPQIAALAVKSGNAVMLKGGSEAAHTNDALASTLQTALASVPGYPAQALQLIHTREESAEMLALDQYFDLIIPRGGNGLIAYVKANTKIPVLGHADGVCHIYVAASADLEMACRICVDAKTQYPSACNAVETLLLDERWPEKNKKALLETLLKNGVSLFGGADIAALARVSGPVTDWHTEYGEKKLSVKQVKNLLEAISHINRFGSHHTDCILTAEHEEAQIFMDLVDSAGVYHNASTRFADGYRYGFGAEVGISTGKTHARGPVGLEGLTIYKYKLYGNGQVVADYVGANAKPFTHKKIGSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER5</accession>
    <name>A0A1Y4DER5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57587">
        <property type="protein sequence ID" value="OUO57587"/>
        <property type="gene ID" value="B5F75_02090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010986173" evidence="1">
        <location>
            <begin position="22"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="16754" checksum="7B150AA3B6F6C716" modified="2017-08-30" version="1">MKKILIAAAAASIIACVFCLARTVSEGRFNISGTVTVPERLARMAEADNNSCAIIVKNEADVPVAIKRVVNPKFPLEFSMGEADLLTASVDGALKLEVQINNHGQLGVVKKGDIFGSVDRMIKPNDKNITVSADKTLGRVQLARNVKGNFFRTAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES9</accession>
    <name>A0A1Y4DES9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secondary thiamine-phosphate synthase enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57597">
        <property type="protein sequence ID" value="OUO57597"/>
        <property type="gene ID" value="B5F75_02150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="15771" checksum="6090F0D5FE75F1EF" modified="2017-08-30" version="1">MKSYTQYLTVCTEKRYQIVNITPQVEEALEKSGIQEGLCLVNSMHITSSVFINDNERGLHADFLRWAEQLAPYGVDKYQHNLTGEDNGDAHLKRTLLGREVVVAVTKGHLDFGPWETIFYGEFDGQRNKRILIKIIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU6</accession>
    <name>A0A1Y4DEU6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57644">
        <property type="protein sequence ID" value="OUO57644"/>
        <property type="gene ID" value="B5F75_02395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="177"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="370" mass="42021" checksum="AD244ED893CAEDE2" modified="2017-08-30" version="1">MKILYVITSTETGGAEKALAELVLYMCQANTVKVISLKPLGAVGRALQQKGIEVESLEMKWYSLRIIQRLAARIKAFHPDIMHAMLYRAIEYTRVACAGTHIPLLTTPHFDLSKKSFALRWTDRILKDLDTLTVAESFTTARYLVEHQNYQKEKVYLLPNGADPRVFFPDEKARNLMRKTYGFAPNQPIFISVARLAPVKDPLTLLQAFRNLLRTVPSARLIYVGEGKERNALEQYIASTHMQKEVFLPGEQAHINDWLNMADVFVLSSVEESLPLALLEALRVGLPCVVSQVGDMPLWVEHGQNGFVFYPQDITLLSCLLTELAQSAELRRKMGARSLELTARMTDTSPQYQHLYQQIKDKSFHVKTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW0</accession>
    <name>A0A1Y4DEW0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56259">
        <property type="protein sequence ID" value="OUO56259"/>
        <property type="gene ID" value="B5F75_06475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186875" description="SBP_bac_5 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="85"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="577" mass="65374" checksum="534F3E176CD826B5" modified="2017-08-30" version="1">MKKSWLMLCLAGLLCAACAQQEMKDSLIVAHKGEMESLDPVYSYDGVTHGLLINVYDTLLKFKGSSLTELEPSLSTQVPTKENGLISPDGLTYTFPIRKGVKFHDGTELTAEDVRYSLLRFLLSDVSGGPSSLLLEPILGVSSTRDADGNIIVNFQDAADAVRVEGDNVVVTLKRPFAPFLSIVARWSYVVSKKWAVQRAAWDGTEETWKQFNNFSKDSSPFFSQENGTGPFRVERWDIAAKRLTLAANEAYFAGAPRLKTIHMMTVDEPSTLRLMLESGDADVAEISTKFAAQLKGNPDITVYDNLPRLRTDPVIFFTLDINMQANPDVGSGQLDGQGIPSNFFADKDLRKGFEYAFDYDAFLEQSMEGRGERAIGPAPAGLVRYDDGFKRYHFDLEKAKEHFQKAWNGQVWEKGFKFTITYNTSGDMRQIASEILKRNVESLNPKFQIDLRGVTWPAFLEKTAKRQMPMWARGWVADYADAHNFYFPFIHSQGRYALSQGYKNPLADRLIEKAVAETDFSKRNLLYRQVHNFMYEDAMQIYTVHPTGLWAMRSNVKNFVDNPVYMGIYFYPMYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEX1</accession>
    <name>A0A1Y4DEX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57626">
        <property type="protein sequence ID" value="OUO57626"/>
        <property type="gene ID" value="B5F75_02295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012599055" evidence="2">
        <location>
            <begin position="27"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="106"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="451" mass="50750" checksum="2D60A4AF81A86573" modified="2017-08-30" version="1">MHYLKPFSNCLALWLALGLLPGELWAAGAKQQNISSCLESGKKAYAAKDYLQAQDVFTRCLKLDSDNVEALLSLAGVLLTQDDLKGAEKYFTAATRSMKRNSPYWSYTYSMLGDIALKQQQNDKALKLYSKSLEYNAANVNSLVGKGVIVEYQGDKQGASEYYRSALAVEPLNLIARKRLINLEPDYLTNDEMLTALKQRYAVEPDATELTDENKALFEKIHQAEQRRGIDYLKNKYAKVPSEYIVTINKDTSFEREMLTLAGYNALEKSIGQDAIAVFQKVGVPIKDVFDLRDMKGEKIFTPESTLTESGFYVYTEALKGRKAFLMPNEAVPPTQAFLAKVSARVQELKDAGYVEITRSEYKMIQNQTKCSDETLRSKLGVYVLPVTKNDVRYFVLARQTADPKKGVAYYYLMAAHAKRNPKVKVPSNSLVESYAFYGYTVCLDDGNLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEX4</accession>
    <name>A0A1Y4DEX4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57465">
        <property type="protein sequence ID" value="OUO57465"/>
        <property type="gene ID" value="B5F75_01445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012892796" description="Response regulatory domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="251"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="387" mass="43750" checksum="01B2827E7D7E702D" modified="2017-08-30" version="1">MNPVSGKWLVGLMAVALASSAYAQTGKQIIKSGSRALSSNAAEMSILKTMDNWYGIGAALKKSPAAASIERAVKQQLPVKETREHAFRNSGFFDPIMATPIRELQINLIHPTTEQVQQAVNEYRSLMRDLAPVRKEVNAKLLYQSLPNDKWVSFPPQERRRLISELAALEGRVEKLRRVVFSNDAALEKVGKWIDEALKQINPYYVPAQRTSARTDSRSFNREEFFLKYPDVSKVPQGVTAPKRELPANIRVAVLNDQTDVLDMYRIWNAQKRLGEGWSVTTYKDTRDLINAIQSGNVYDLIITDLTVPGGGGYYLVDEVRSMGLNMPIIGCSMYTIDKLNAEKMFEQGFDGYIYGDDMFEEIAGSVSWVGYIKNYYYYKALHGWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEX5</accession>
    <name>A0A1Y4DEX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Desulfoferrodoxin</fullName>
            <ecNumber evidence="5">1.15.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Superoxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">B5F75_02415</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+) + reduced [rubredoxin] + superoxide = H2O2 + oxidized [rubredoxin]</text>
            <dbReference type="Rhea" id="RHEA:21324"/>
            <dbReference type="Rhea" id="RHEA-COMP:10302"/>
            <dbReference type="Rhea" id="RHEA-COMP:10303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.15.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the desulfoferrodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.2" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57647">
        <property type="protein sequence ID" value="OUO57647"/>
        <property type="gene ID" value="B5F75_02415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050605">
        <property type="term" value="F:superoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00974">
        <property type="entry name" value="DSRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002742">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036073">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004462">
        <property type="entry name" value="Desulfoferrodoxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038094">
        <property type="entry name" value="Desulfoferrodoxin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004793">
        <property type="entry name" value="Desulfoferrodoxin_rbo"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06397">
        <property type="entry name" value="Desulfoferrod_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01880">
        <property type="entry name" value="Desulfoferrodox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49367">
        <property type="entry name" value="SSF49367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00319">
        <property type="entry name" value="desulf_FeS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00320">
        <property type="entry name" value="dfx_rbo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00332">
        <property type="entry name" value="neela_ferrous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Desulfoferrod_N" evidence="14">
        <location>
            <begin position="2"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Desulfoferrodox" evidence="13">
        <location>
            <begin position="42"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF06397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="128" mass="14190" checksum="7D5D5D95697F501A" modified="2017-08-30" version="1">MTKVNEIYKCSVCGNMVEVVHAGGGELVCCGKPMQLQNPGTTDGATEKHVPVIEKIEGGYRVKVGSVAHPMLDAHYIEWIELICEECGKVQRKYLKPGDAPEAVFETKAEKVTAREYCNLHGLWQKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY1</accession>
    <name>A0A1Y4DEY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57475">
        <property type="protein sequence ID" value="OUO57475"/>
        <property type="gene ID" value="B5F75_01510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="64" mass="7719" checksum="12B999A9898C7960" modified="2017-08-30" version="1">MDNIIIQLEEYRLKHRITQQDLARKLGVSFVSVNRWLNGHARPQKLQVYQIKQLLQDKEVQYVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY4</accession>
    <name>A0A1Y4DEY4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GFO_IDH_MocA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56279">
        <property type="protein sequence ID" value="OUO56279"/>
        <property type="gene ID" value="B5F75_06590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="357" mass="39534" checksum="C7E0D1F87C15CBC2" modified="2017-08-30" version="1">MIFMAQDKPLKFGVIGAGKIGTFHTRTLANMKGVSLVGVCDPDLMRAQKLAWEHNCTPYSKPEELVGQVDAVIVAAPTQLHHQIGMYCLEHGVHTLVEKPIAVTMQEARDLIQCAKRQGLVLQVGHVERFNPAVVEAVKYIEDPRFITITRQGPYDGRMANISVVLDLMIHDLDLLYTIVPSEVVSIDAVGLSVFSPHEDIANVRLHFANGAVADVTASRASFERARFMHLFQPSGYVSVDFMNARVKTYRKEKPVIENMNDLTVTYPKVEKQLPITAEILHFIDCIKTAKTPAPSGEKGMKALDLALQICEKMNRFDIPKTGHLHTPRPLQAISTVARAAQAVLDETLGHLKGDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY6</accession>
    <name>A0A1Y4DEY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="18" type="ORF">B5F75_02610</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57684">
        <property type="protein sequence ID" value="OUO57684"/>
        <property type="gene ID" value="B5F75_02610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="431"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="15">
        <location>
            <begin position="624"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OUO57684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="668" mass="76175" checksum="1B60EAEF6D220B80" modified="2017-08-30" version="1">MDHFKLVSPFKPAGDQPKAIEALTQGVLAGVPRQTLLGVTGSGKTFTMANVIERLNRPTLILSPNKVLAAQLYAEFKQFFPENAVEYFISYYDYYQPEAYIPQTDTYIEKDSAVNEHIDKLRLKATTSLLTRRDVIVVASVSCIYNIGSPDSFREMRIYVKKGAEMTRSSLSGQLIKIQYRRDEMEFASGNFRMRGPYTDIMTPYSQNAIRVEIAGKTIAHIYEIHPITGNVLAELDEAWIYPAKHFVATDEDTQNAIEQIRRDLDIRHAELLKMGKELEAYRLKQRTEYDLEMLQQAGFCPGIENYSRYMDGRKPGERPACLLDYFKRYDDFLMMVDESHVALPQVRGMFNGDRARKQMLVDFGFRLPSALDNRPLKFDEFEKLMPATVFVSATPGPYELTVSGNHIVEQVIRPTGLVDPKVYIHPTAGQIDHLVGKITEHKKRGERTLVLALTKKTAEDLSAFFTEKNIKTRYLHSDIEALDRVEILKEFRQGKFDVLVGINLLREGIDIPQVGLVAILGADNEGFLRNTTTLIQISGRAARNADGEVILYADRQTDSIKYALNEMNRRRQLQEAYNKEHHITPKTIQKMEVDLKELQQQTKTSAFGILSQTLPEPTLKNIQSVEKDLEQQMLQAADALNFELAAELRDRLFELRQMRVKGGGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF85</accession>
    <name>A0A1Y4DF85_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57595">
        <property type="protein sequence ID" value="OUO57595"/>
        <property type="gene ID" value="B5F75_02130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="75"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="314" mass="34976" checksum="1F554BAB90EB75E3" modified="2017-08-30" version="1">MSMVASSGHLYSCFFFFIEEVLLYALLYKKVSIVQKSTFLLKLHKIPIIKAGGKPMKITQIRNATLWIEYPNVKFLVDPWLGPKEYMPGFEGAIHPEIRQPRTDLPFPAQTVAQADAVILTHVHPDHWDAYAEEALPKDIPFFVQSEADQKYVAGKGFTRVSVLSEGGTLFRGVTLHKTRGQHGERTKVEPACRQLGMPYDAMGVVMKAEGEKTLYLAGDTIFCEEVQQALHTYRPEVVIVNACAARVASGDRLIMDEQDVEQTSLAAPQAVIVASHMDEVSHASVTRAQLAAFARQHRLDKLLIPADGETLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFE3</accession>
    <name>A0A1Y4DFE3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57362">
        <property type="protein sequence ID" value="OUO57362"/>
        <property type="gene ID" value="B5F75_00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="87" mass="10181" checksum="BB19792B869BEC3D" modified="2017-08-30" version="1">MTKHLILFASRMRRAFRQEREKTLRQQDIRTVCIQEQIICLSEQEAAFVALETSRLLRAQRQEAKRKKRLGIPPPPAPGKIAYAVYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFV4</accession>
    <name>A0A1Y4DFV4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T2SP_E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56559">
        <property type="protein sequence ID" value="OUO56559"/>
        <property type="gene ID" value="B5F75_05030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="196"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="363" mass="40316" checksum="268E66B8706BCC7E" modified="2017-08-30" version="1">MAVGLQSLLRTVVDNKASGLHIRGNSNAYVRLNGQIKPIDDSFVSNDEAKKMAYACMGERERRIFEQYSTVDFSLDAKSYGRFRFNVFRQMSKICMAIRHIPLKIPSFEDLHLPGDILRKIADNRRGLILVTGMTGSGKTSTLAAMIDYINKTRPGHILTIEDPIEFMHTDNRCIVSQLELGVDTPSYTGALRAAMRQDPDVILIGELRDGEVMKAAIGAAETGQLVLGTMHTVNVTQTLARLVDAFPVEQHEQVRLQLSELVRGIVCQRLLPTIKPGMRPALEILVSTPQVRKLILENKPSDLYKMMQGGEFYGMNTFDQSLARLYKEGFIDLETAQSAATSPDAIMLAIRGVTNSLDAVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG59</accession>
    <name>A0A1Y4DG59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57632">
        <property type="protein sequence ID" value="OUO57632"/>
        <property type="gene ID" value="B5F75_02325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169748" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="28"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="26743" checksum="5A8E16BBF27B1283" modified="2017-08-30" version="1">MKKSFWLAVLIGISCVWPVWSHAQGIQAGDQFISVYAGAGGATNDTHLGLDFRDDTGYPLGQTKDFGWGDESVAFGAQYLYTVSPYWAFGVEYNANLFDGAAEELNAWGGSGQHMKAEADQDMDVHNLMAAGRFTLNPQGTFRFYIPFGAGIAFSKATVKNSFWEQNGGAYTSVSDSRSESSRSFTYYTGLGVEHRLAGQWLWGLEGRYQSFSFDYDKFLSGAGRENLHYVTVFLKRGYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGV3</accession>
    <name>A0A1Y4DGV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56158">
        <property type="protein sequence ID" value="OUO56158"/>
        <property type="gene ID" value="B5F75_05945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013322877" evidence="3">
        <location>
            <begin position="22"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="442" mass="48726" checksum="164CEA3593407748" modified="2017-08-30" version="1">MFKFLLLTAALFWGTGASAWAAPVQAVLFTSPYCPHCRHLKEDGFPQQFREKYKGKAELFEYDLTEQANNVLFFQTLQAYGLDSAGIPMLVIGETVLQGYPTQIGSQADEAVQKAHSNREKTRVPGLPEPKAETAPVKKAQPAAPATTEPDPAEPAPVQTAPQPAPVQAPAALAEPAPTPAAAAQENSQLQAHEALFSQITLWAIIGAGLADGINPCAFAVIVFFVSFLAAYKYTKKEIIVVGTAYCTSVFLAYLLMGLGAFHFLYAMKGFRYVTLAVQWGTIVLCVLFLALSLYDFIIYQRTKKSEKMLLQLPKSYKEYIHKVMRFFLKDKHSSMWRLLLAAFAVGFVVSAVEAVCTGQVYLPTCVVILKEAGSQSWKAAEYLIVYNLMFVLPLVLVFVLTLCGKESATFNNWLKKHLGLSKFLLCCVFLGLLLLMLANMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH63</accession>
    <name>A0A1Y4DH63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57019">
        <property type="protein sequence ID" value="OUO57019"/>
        <property type="gene ID" value="B5F75_04015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="605" mass="64824" checksum="77503A538288D420" modified="2017-08-30" version="1">MQITKRIYQGNGITRKWDVDFPLLSAADLRIYVTSPQGAEEEISSDFSVDLLTHTLTYPTDESGKAALADGWKLTAVRATPLTQEIDLLRQGELDAEVLEEGYDKLTLLVQELEEKVDRSIKYPVSSQENDLETDNFLANILSAKEAAVLASQEAAHSAQAAQQTASDAQQTITQAQQNFTQETETFSENLQNKEQSIYQAAEGYVAQAAQQAQTAKNWALKTDGPVEGEEFSAKKYAQEAAQAASTAAMINKISNCLTKIPQDIKLSVSSGTLTLGSGSKAYSGSGSVINITQNLTASSSGAGSFLVFAKADASALVLCPLANCSSGTSDPQTENTVYYNTSTKTVSYYASANTPTEVSLPLGVCTASGQITSVDQVFNGFGFIGKTIFVLPGVEGLYPNGRNADGSLNNVSVIVNAVMTYTSSSAGQKEVYLKSNDFSDVGEAAIDYDETQNKNIYTSNGTTASYALVGRAIRTEGGNIVSLMPQNVFRAVDYGDVYKRTTVYSSDGSNATITFPTPIKAKDARYLEVVYTAKGKSYTSVIPSVFAPLGIVVGSLNWGGDQTDRDYDCVMNVTCAGGYITAFTSLGRDIYIKRVDVVDYLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHM4</accession>
    <name>A0A1Y4DHM4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56428">
        <property type="protein sequence ID" value="OUO56428"/>
        <property type="gene ID" value="B5F75_04330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="56" mass="5738" checksum="BAA56C6F0B26BBEB" modified="2017-08-30" version="1">MAYKVNPDVCINCGACESACPVTAISEVEGKRKIDETKCIECGACAGTCPVSAIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHN4</accession>
    <name>A0A1Y4DHN4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56438">
        <property type="protein sequence ID" value="OUO56438"/>
        <property type="gene ID" value="B5F75_04390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="264" mass="30228" checksum="0FC270045D337DBE" modified="2017-08-30" version="1">MKKSRIFLSVVLLAVVAFGAYAAFMYVYTEWKFLPVELLQEPSLEAPHSEWKAPQELLYIHKVNTPRRADAKDDWFEGYEVDLISTSDGKLAVAHDLDEIEDGIRLSDIFAAVDDPAQKAYWLDLKSELTPEQLNQILLTAKAFGVPTDNLLFESVPGKTAKMIKEKDLSLLLQLPDEFDKDGGDPQKRKQLNEQALKQWQEYLPAAVSTSFGKYPYLRAYFPKMPKAIYYSSTVRPSLKKPFMVNNIKEDPSVKIFMIDQYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHR5</accession>
    <name>A0A1Y4DHR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57219">
        <property type="protein sequence ID" value="OUO57219"/>
        <property type="gene ID" value="B5F75_00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="210" mass="23235" checksum="E8DBA53B8124EDD1" modified="2017-08-30" version="1">MGRTSSGTDEKLIQTGIRLARVRGLGGFTVRELCAESQVNLGMFHYCFINKDNFDRALLSTLYENLMKNIRLEVSDDKSARANVLNILLAIQRFVRENRRLLSSLAGDVFSGNAKIIDFIGRNFTHHISVLLAQLERAEKEGQLVLKDAANAALVLAMPVVFPQLVAGLDERVPLPWKGRVRPSVTALFSDKGAAERIQVLVGAVFKGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI73</accession>
    <name>A0A1Y4DI73_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57359">
        <property type="protein sequence ID" value="OUO57359"/>
        <property type="gene ID" value="B5F75_00885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="7"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="200" mass="22132" checksum="37D5BAF4C6A27F6D" modified="2017-08-30" version="1">MQLSEIKFACLDTETTGLSPLEGGKICEIAVSVSQGGRVTEEFSTLINPDMPMHPDVVAIHGITNEMVASAPRFAAVLPKLLSLLDNCVIVAHNADFDVGFLKSEFAQCGMKFPPYPVLDTLKLARKSGRFAKNNLGCIAADLGINPQGWHRAMADTKMAEQIFYYFLTILSKHGVQTLEQLEPFQYKRWKDLIAVNKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIG9</accession>
    <name>A0A1Y4DIG9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillin-binding protein activator LpoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57459">
        <property type="protein sequence ID" value="OUO57459"/>
        <property type="gene ID" value="B5F75_01415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014094">
        <property type="entry name" value="LpoB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40593">
        <property type="entry name" value="PTHR40593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13036">
        <property type="entry name" value="LpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02722">
        <property type="entry name" value="lp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012508847" evidence="1">
        <location>
            <begin position="24"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="196" mass="22009" checksum="A343B644F6C10A89" modified="2017-08-30" version="1">MKKYFIALLAMPLLFACAPSVKRVETNLVKDVSGGWNDTDAQMVAQEMITDCLQGGWYNRFLTRNGKEPTVIVGTVTNNTMEHINTGVFIESMQRALINSAKVDFVASADERGEIRTERLEQDEFASEATRKAFGQEIGADYMLSGVLNSVVDQSGSKAVVFYQVNLKLIDIETNQIVWNGQKQIKKYVKRSKVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIM4</accession>
    <name>A0A1Y4DIM4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prepilin leader peptidase/N-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.4.23.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">B5F75_06010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.</text>
            <dbReference type="EC" id="3.4.23.43"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase A24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.4.23.43" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56170">
        <property type="protein sequence ID" value="OUO56170"/>
        <property type="gene ID" value="B5F75_06010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010627">
        <property type="entry name" value="Pept_A24A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014032">
        <property type="entry name" value="Peptidase_A24A_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06750">
        <property type="entry name" value="DiS_P_DiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00864">
        <property type="entry name" value="PREPILNPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="190"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="DiS_P_DiS" evidence="13">
        <location>
            <begin position="11"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="12">
        <location>
            <begin position="107"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="260" mass="28501" checksum="EB8FE265EDBF6A0E" modified="2017-08-30" version="1">MDTLILCFAGIFGLLFGSFLNVCIYRIPRDKSIVWPPSSCPGCNARIKWYDNIPVLSYLWLRGKCRSCKQPISLQYPVVELLTGALTVLFVWRFGLSVWTFVTVAAVYALIILSVIDLELMIIPDRFSLGLIVLGLAFAWANPNFSGVWWQKELSSLLGAGVGLFGVLAIALIGTWMFKKEAMGGGDVKLMGGVGAFIGWEGVITTVVFASFFGLVYALFLMIFKGKKGGDAIPFGPFLSLGALINLLWLIKPAMLVIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIR0</accession>
    <name>A0A1Y4DIR0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56200">
        <property type="protein sequence ID" value="OUO56200"/>
        <property type="gene ID" value="B5F75_06170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="234" mass="25947" checksum="9EE1634D314C11E8" modified="2017-08-30" version="1">MSSSVHFKEIDSTNNYLKEHCAQLPHGFIVTADKQTAGRGRFNRKWVSQEGGLYFSVLIKPEQTDFWPNFTQLMGLSLCRAIEKRYPKTYLKWPNDVLADGKKLCGILSEGVLCGGKLEGMIIGTGVNVGQKTMPDVGQPATSLYLLGVQADKQTLLGEIMDYFWQDYPAVQARGFAAICEPYRARFPFIGKEITVKNGEKPLCGTVRDVSSRGTLLLNTADGPEEIYIGDLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIR5</accession>
    <name>A0A1Y4DIR5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56828">
        <property type="protein sequence ID" value="OUO56828"/>
        <property type="gene ID" value="B5F75_03000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012124600" evidence="2">
        <location>
            <begin position="23"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="339" mass="38491" checksum="D924688F1AFBBD7C" modified="2017-08-30" version="1">MKIIRFLLLAVFAMPVYTSAQATYGIPMGNGFAWDTKIPVTFDPVAFNKKFAKQMSAVRAAAALQEAPKTKEAPQPAAKALPTVKEEDYTQCAVCHEKILKSDGYQITPKRDWYVKKHSPCACQFYKGWKASEDTSFFQTAAKRNECELKVDSKYATHTCAVCGKPINPACGAISSWEDDQGKHYAHADCFDWQRHNAQKEALLKNLDITEADCNRYDRQDQERINAQKQLIEEMKASSQRIREQQEKASKQELKPAEAAMVEPVVRPFKKVQRDFQRFNRRYGKALHQAAKAQREGKELSQKQQKLLKDFESLRLEYERSSQAAVAQEAAAKKAAAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIW3</accession>
    <name>A0A1Y4DIW3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplT</name>
        <name evidence="7" type="ORF">B5F75_02260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57619">
        <property type="protein sequence ID" value="OUO57619"/>
        <property type="gene ID" value="B5F75_02260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="115" mass="13175" checksum="64FF1DF13EA4C54E" modified="2017-08-30" version="1">MRIKFSVARHARKKKVLKRASGYYGDKSRRLRMATQQLDKSGVHAYVGRKDKKTTYRQLWITRINAAVREEGLSYSKFISGLAKANITLNRKMLSEMAIKDPVSFKKLVDVVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ11</accession>
    <name>A0A1Y4DJ11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56938">
        <property type="protein sequence ID" value="OUO56938"/>
        <property type="gene ID" value="B5F75_03585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20348" checksum="2AC3DCB70C89E59D" modified="2017-08-30" version="1">MKTLFGRYGWAVALLTVAGALMLLGSAPVSAEQSPFEQLRRQMPAKLDLLRDRVDEAGGQDLSLALFLAVQSEDAHTVGTTVLVYQQYPRERKLAVLLAAAVKYHKEMSLMQRVEDQSLKQALAEAPAEMAGINGMFQTVQDSLSMTPEVLKDTVRKAQSHNMQRKAAEAVKRTVKHNLGQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ55</accession>
    <name>A0A1Y4DJ55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">T2SP_E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03785</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56978">
        <property type="protein sequence ID" value="OUO56978"/>
        <property type="gene ID" value="B5F75_03785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="393"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="581" mass="64554" checksum="8269E180B7CA6C7F" modified="2017-08-30" version="1">MAKQLSEILMEQGTLTAEQIKRAQLYAKQNNVSVAEAIVKFGFASEEEVTVALSKHFAVPYASKENGILVPEREQNLQEIIPEKFARENMVIPLFIEDDELAVALLDPTNMFLLDNIKMMSGKQVQPFIASKSQLLRVIDSFYSNKNLLEEVMNEAAKPISEEVSAATAESDEEVEVTGVLDLDKVSPNSSQYVKQVNAILRQAISERTSDIHLEMFDERVSLRFRIDGSLYERTPPAKESVNAIISRIKILSKLDIAEKRLPQDGSFTIRYQNRSIEVRVSVCPAVYGEKLVLRILDKGTGEMNIDKLGFEPDQKKAFLEAANLPHGLIFLTGPTGSGKSTTLNAVLTTIRTPELNFMTLEDPVEYKLAGISQVQVKPAIGLTFAAGLRSFLRQDPDVILVGEVRDNETAEACLKAALTGHLVLSTLHTNDALGAVPRLIDMGMEPFLLASSLALVAAQRLVRILCPYCKVPHIPDSAMLARIIQEGHLNPRDQNSWTFFKSVGCPKCFGTGFMGRRAIYEVYRMTEEMRTIIYKTQDLVELKRAAVRSGALNLRANGWHKVIRGLTTVDEILSITTADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJE1</accession>
    <name>A0A1Y4DJE1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase subunit sigma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56440">
        <property type="protein sequence ID" value="OUO56440"/>
        <property type="gene ID" value="B5F75_04400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="245" mass="27180" checksum="E62898A90F03BFB9" modified="2017-08-30" version="1">MNSELKEAAKWIKNASYGVVFTGAGVSVESGIAPFTGQGGLWNQYDPKYIEINFFQMHPAESWREMKKIFFTDMDEASPNKAHEVIAKLEEKGYVKGVITQNIDGLHQRAGSKNVQEFHGTIHTLSCVRCGRKYKLEDVNLEEEPPHCFCGGVLKPDFVFYGEGIPPRAYEKSLEMAQNAEVMIIVGTAGQVMPACSLPLVAKQFGAKIIEVNPQASSFTGTITDLYFAQKAGDFFAQLEKELKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJI0</accession>
    <name>A0A1Y4DJI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56480">
        <property type="protein sequence ID" value="OUO56480"/>
        <property type="gene ID" value="B5F75_04610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030192">
        <property type="entry name" value="YbdG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30414">
        <property type="entry name" value="PTHR30414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="426" mass="48117" checksum="6416264B81EA0E43" modified="2017-08-30" version="1">MNFILPYVEKIPYIPDKYNTLIAQVIAAVLFVLVLYAAARAASWFCNRYLGRLVSRFNSGRWFKALSEHHFFTAMGVVVAALLAINLYPVFISSKVAVLTTLMGKLTGLFVVMSFAWLVNSILNTAGRLYGLNPSVPIKGLVQALKIILFLITALFVLSLLLGRRPMYIITGLSALAAVFSLIFKDPILGFAASIQLTTNKLIKIGDWITVDSAGADGNIIDISLTSVRVQNFDMTIVSVPTYDMISKPFKNWNGMYLAKARRIQRSILIDVDTVKFLDRPMLERLKKIQLLKDYLEQKETEIKAFNAERNVKENFLNGRHLTNIGTFRHYAELYLASRPYVVSDNPNLTLMVRQLKQEAQGLPLEVYCFLNTTVWTDYEALQSDIFDHLFSVLPEFGLYAYQQPSGRNIAQGIQMLSYQPPVQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJJ0</accession>
    <name>A0A1Y4DJJ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ORF">B5F75_04665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56490">
        <property type="protein sequence ID" value="OUO56490"/>
        <property type="gene ID" value="B5F75_04665"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="21"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="21870" checksum="A9C33D89CFB4983E" modified="2017-08-30" version="1">MPQPSWKVNEIFYSIQGEGKHTGMPAVFIRLAGCSMNCPFCDTKYAARDGQTLQAEAILKALASWPAKAVIITGGEPSEQDLPALIGVLKDAGYEVHLETNGANDTDVSRADFVCVSPKRYVSPQMLKKAHVIKLVVGQETDLEDLQKYYAYENAHTQIYLQPESNKQENIDLCVKLLKNHPSARLSLQTHKLANIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKK4</accession>
    <name>A0A1Y4DKK4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pnp</name>
        <name evidence="8" type="ORF">B5F75_03010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56830">
        <property type="protein sequence ID" value="OUO56830"/>
        <property type="gene ID" value="B5F75_03010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="7">
        <location>
            <begin position="631"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="703" mass="76707" checksum="DAC1F9319935FF1B" modified="2017-08-30" version="1">MQNFNHKFDIHNVEVTVGGQTIKLETGLIAKQSDGAVVATLGETMVLATAVSTKEQKPGISDFTPLTVNYKERTYAAGKIPGGFFKREGRASKKETLSSRIIDRTIRPIFPEGFACETNVTAMVISSDDKHDADVLSVLASSAALVISSIPFNEPVAAVRIGRKDGQYIVNPTKKEQESCDMDLVIAGSAQGLLMVEGGAKEVEEEAIIKAMEIAKPEIDKMCAAQMKLREMAGKPKFEYVVEKLPQEVADLANGKFREEAKKILHAFSDKQTRDTQVAQLKASFTEELTPNYGENAAVYAGIALENIMYEESRNLVLHEGVRVDGRKPDEIRPLSSMVGLLPRAHGSALFTRGQTQSLAVATLGTPDDQQMVEGLDDTTYERFMLHYNFPGFATGECKPDRSPGRREIGHGELARRALMPLIPSEEEFPYTIRVVSDIMESNGSSSMASVCGGSLALFDAGVPMKSACSGIAMGAISGEGKFVVLSDIMGLEDHLGDMDFKLTGSRKGITAFQMDVKLKTGIPLDVLRQAISQATQGRMFIMDHMEKTIAEPRKNISRFAPIIYKMRIPVDKIGALIGPGGKNIKRITESTEAKIDIAEDGIVTIAAANSDRLDQAKAEIEMMTAEPEVNKIYKGKVVSIQPFGAFVEILPGKDGLLHISEIEKHRINKVEDVLKLGDIVEVKCVEIDNNGKVRLSRKALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKX3</accession>
    <name>A0A1Y4DKX3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="2">dTTPase/UTPase</shortName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56950">
        <property type="protein sequence ID" value="OUO56950"/>
        <property type="gene ID" value="B5F75_03645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="185" mass="20685" checksum="0332D094691A41A8" modified="2017-08-30" version="1">MQLVLASKSPRRIAILKELGMKFDIIPSQAPENSRKKRPAARVKELAVQKAFDVARKYPGAVVIGADTLVYCKGEIIGKPKDRADALRILKKLNGAWQSVYTGVCVMNLQEQKMLFGHDVSKCKARRLSPQELEHLAGKHMDKAGAYAVQDTDDPFIERIVGSRSNVVGFPVEFFQKLFKEFLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL81</accession>
    <name>A0A1Y4DL81_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57688">
        <property type="protein sequence ID" value="OUO57688"/>
        <property type="gene ID" value="B5F75_02630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="53"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="261" mass="28394" checksum="041BEFFC4BDE632B" modified="2017-08-30" version="1">MSAPLSASIRLYGKAPYTLALLHGGPGARGSLAGLAAQVGQKRAAAELLQTAFSVAELLQELHAQIQTLTPPVALAGHSWGAWLGLLYAAIHPQNVRHLVLISCPPLTDEFVPQILERRLSLLTPPEAKAFQEALRQLEKNNAASPQALRTLEELSQKTDFAFPAPYDDSALEVDARQYQAVWPQAARLRTEGVLLQAARGLECPVSVLHGLQDPHPAAGVLEPLTACGIRPQTILWERCSHSPFAEKYAQRELCRFLQQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLG7</accession>
    <name>A0A1Y4DLG7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YfiO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56251">
        <property type="protein sequence ID" value="OUO56251"/>
        <property type="gene ID" value="B5F75_06430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YfiO" evidence="2">
        <location>
            <begin position="108"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="229" mass="24741" checksum="67A5D77A944D49DE" modified="2017-08-30" version="1">MKNVTKLLFMAGSGFLLSGCIASERDMSTLKLQLQELNSTIVQMQANQAELASKMDELNRNLSVSNENLSQVDAQIFKLSAKLDDLTATVRPASGGAAEGAQPAALLPSDLFAESKSHLDKGAYEPAAMGFKLYVSKYPDSENVEQAYMYMGDAYIAAGQTKQGAIAYATLLQKFPKSKFIPAARVKYALSIVPLGKNDEAKRYLSSVVQEFPSSPEAQTAKAELAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLP5</accession>
    <name>A0A1Y4DLP5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Penicillin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_06820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56321">
        <property type="protein sequence ID" value="OUO56321"/>
        <property type="gene ID" value="B5F75_06820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="263"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="618" mass="68134" checksum="94010B7884D5F961" modified="2017-08-30" version="1">MAVTKIFFNARLKVMMALACIAGGVIALRLVDIQVLRHQAYLQMAERNRTQVIYQTAPRGRVFTADGVAVATNAPSFSFYYLGAGNTDPAYLEQLARDFAPRLKMTPQEILAKLEQGVKTGKATLLAENLSTKSTVALQELQLYYPGVYLIEETKRTYPYGGFASHLLGYIGSMDDREWRNRDLRMGYRLNSKIGKNGIEKKFEKELKGRDGGVYLEVDYRGRVKSIIQDKKWSAGSDVYLTLDFKLQQAAEEGLKKSNTGRGAAVALDPRTGAVLAMASAPAYDPNIFVQYSDEENPKQSKKISEYNLAIQGTYPPASTFKIITAAAALEYGHLDVHRKINCPGYYDSGPRVFKCWGTHGPVDFFDGMSNSCDVYFYQVAAQTGSAAIERVQRKFMFGRQTGIDLPGEKAGNLYGPTRRARNKTYWFIGDTLNLSIGQGELLVTPLKLAQFAAAVASRGNVYRPYYVDKIVSNQTGKVQQIGKTEILQKADLKPETYDLLFQALKHTVDHGTAARVRIEGLDVYGKTGTAQNPHGDDHGWFLAFAGRKGEEPSIALAVFVEFGKGGSSAAGPIARSMLEAYFGVEKPAPKPAAAKVPQRTEEDYEELLTPGEQDGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLW6</accession>
    <name>A0A1Y4DLW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57290">
        <property type="protein sequence ID" value="OUO57290"/>
        <property type="gene ID" value="B5F75_00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186882" evidence="3">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="219" mass="24747" checksum="43F1DE55EAC4CF7E" modified="2017-08-30" version="1">MKKFACLILLLAVNSAYAGVRADLRQGGKLYENKKYGQALSKYNEILQENPKNEDASFGAGAAAYYLKDYQAAEKSFEQTVQQQGELEQDALFNLGNAYYRAGNVKEAEKAYRQAIVKNPKDKEAIHNLQILLQQQQNQQNQNNQNQQNQDPNSSNQNQQNQNDQGASQDQQDQPSPSDLQDQMDKTDADRVMQMARENEYKKPTQTGSAQGSSVEKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM38</accession>
    <name>A0A1Y4DM38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56461">
        <property type="protein sequence ID" value="OUO56461"/>
        <property type="gene ID" value="B5F75_04515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="222" mass="24434" checksum="1E01686B9B9BF167" modified="2017-08-30" version="1">MAEESFKIRLRFPGGEEFEAQGNQQFVEQQRNYFLTLIGKQKGRSTLSAEPALTRTSAFQESSDSHPKESPATRNNMPALSILPPAEREKPVISPAPQPAGIEGAGTFPALRLWERLLKEDGDIVLLRKKMRLSAPEAALLLLAGTRVLLKKPACAALDLARSLKKSGFSEGRLDRLLAPEIRSGHLTCEGTKRGRTYRLTNEGFAKAFVLAEKLGNENPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM57</accession>
    <name>A0A1Y4DM57_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56481">
        <property type="protein sequence ID" value="OUO56481"/>
        <property type="gene ID" value="B5F75_04615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012621690" evidence="2">
        <location>
            <begin position="24"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="297" mass="34005" checksum="D7EF7E39DF9F122A" modified="2017-08-30" version="1">MKKTWLSAILILCLGACYTPLNNSGVATTKPWLEVSGKKLDFDGKQYDSCYQFNIHFWPPEAVEQIDLQKSCISACCWRSDQDEVTLDFNKNFERDLAYYGRAKKYSPDKITFKVTHSNLVNTTKVTVTPRGVIKNNGLVKLSYKEYENPSRLAQLEAMSRQLQTRRNAYLNEQRQQQDEAARNSKKKNKEEQSAEARAKALLVRKAGTKIDTYFYEMNKTYTRQGAVFMLSERILNTSPLNTQGDYSISCHAQARTGINSKKLKASSFSCGTWRVSLQDETVLPDDRKALQIMQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM67</accession>
    <name>A0A1Y4DM67_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="8" type="ORF">B5F75_04670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56491">
        <property type="protein sequence ID" value="OUO56491"/>
        <property type="gene ID" value="B5F75_04670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="7">
        <location>
            <begin position="32"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="206" mass="23272" checksum="1A61C382FC716A34" modified="2017-08-30" version="1">MRKTAKKSSLRTAKPANAQAGKHPLSEEKILNNLREILAYIGDDPTREGLLETPARIVRSWKKLFGGYQMKPQDVLKTFTEGSCEEMVVLKDIEFYSTCEHHLQPFFGTISIGYLPKGRVLGISKLARLVEVFARRLQIQEKLVAQIADSLMDTLQPHGVMVVCKAKHMCISSRGIEKHNAVMVTSAIRGAFKKMEVRNEFLEMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM75</accession>
    <name>A0A1Y4DM75_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable butyrate kinase</fullName>
            <shortName evidence="3">BK</shortName>
            <ecNumber evidence="3">2.7.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Branched-chain carboxylic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">buk</name>
        <name evidence="5" type="ORF">B5F75_01100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + butanoate = ADP + butanoyl phosphate</text>
            <dbReference type="Rhea" id="RHEA:13585"/>
            <dbReference type="ChEBI" id="CHEBI:17968"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58079"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.7" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57400">
        <property type="protein sequence ID" value="OUO57400"/>
        <property type="gene ID" value="B5F75_01100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047761">
        <property type="term" value="F:butyrate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00542">
        <property type="entry name" value="Butyrate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011245">
        <property type="entry name" value="Butyrate_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060:SF3">
        <property type="entry name" value="PTHR21060:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036458">
        <property type="entry name" value="Butyrate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02707">
        <property type="entry name" value="butyr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="370" mass="40628" checksum="DCB0D0AEE7052EB8" modified="2017-08-30" version="1">MAYNILVINPGSTSDDIGYYRGDKPVFEVTVRYSLTDLEPYEGKNVTEQLPLRRKLILDYLLDHKVPLKEIDAVIGRGGFIRAMEGGVYAVNDQMVSDLETGRYGGIHPSNLGGILAKEIAQYAGCPSFIANPVVIDELQPVARYSGMPENPRISIFHALSQKRVARLIAEKMGTHYEKVNCIVCHGGGGITVGAHRQGKVVDVNNGYEGDGPMTPQRSGGTPNAGLVQMCFSGKYTLRDIRLKLRGKGGLVAYTGTSDVKDLEEFIRTGEKRPGSLIHCTREEAKLAEDAMIYQISKYIGSMAVVLEGKVDFIALTGGLMHSKIIPQEISRYVGWIAPMYVFPGSEEKDALRDAARRALDNPKIVKQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMA9</accession>
    <name>A0A1Y4DMA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56531">
        <property type="protein sequence ID" value="OUO56531"/>
        <property type="gene ID" value="B5F75_04885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="96"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="341" mass="37803" checksum="7D697B55B432A62D" modified="2017-08-30" version="1">MLNYIVRRLLLLPLVVLGVTFLLFFLTQRLSPEMRASLYVKDPRQMGALEEVIRQYGLRDNVFKQYGRWLANVAQGDLGYSPSANMPVAQAIKEYLPATIQLAFITILFVVFFGVWFGSASAVHKDKWQDIVARLVSVGGFSLPIFVLGLILLMIFYGKLGWFAPGGYSVQTDMIIHGGAFKTYTGFLLVDSLLNGNLRVFGDVLSHLVLPAVTLCIGSFALMVRVMRSSMLEELNKDYVRTARAKGLTQWQVVYKHAGKNAIIPVITLASIQFIRLLGGTVIVETIFDYPGIGRFGVIAAQQLDIAGILGFSLMVAVLFVLGNLLSDILYTAVDPRIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMD9</accession>
    <name>A0A1Y4DMD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57460">
        <property type="protein sequence ID" value="OUO57460"/>
        <property type="gene ID" value="B5F75_01420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="147" mass="16504" checksum="38FE9843AE2BC381" modified="2017-08-30" version="1">MFVEQRGSIHTIVLILVVIVGFGLALGWPQYKKHQTLAKAQRALELGKALAFAEATYKTQHGAYTPDFARLDFELPCPVQREDGKIEMVCSDYVYRLEEGNILRVQHKGLPKWFDLDLEKGSVDCSHEEGSIAGSHICERVDLSAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMH6</accession>
    <name>A0A1Y4DMH6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56591">
        <property type="protein sequence ID" value="OUO56591"/>
        <property type="gene ID" value="B5F75_05205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="241" mass="26948" checksum="302429366BE50861" modified="2017-08-30" version="1">MLNLTMPLTSSNPILSVVLPCLNEEQSLAVCLREIKQTADKMHIPYEIIVADNRSTDGSAQVARSFGARVVPVARRGYGAAVNGGILAARGEVVLFGDADCSYPFYDIPKLVTPILQGKQDFVLGNRLNNTQEKGSMPWMNRYFGTPVLSALIRWFYGIAVYDCNGGMRAFLRKIYAPLGLKQPGMEYASEMLIAAAKQNLRYLEVPIALRRAHPSHTPYLRPWRDGMRHLYIILKSLFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMN0</accession>
    <name>A0A1Y4DMN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_01955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57560">
        <property type="protein sequence ID" value="OUO57560"/>
        <property type="gene ID" value="B5F75_01955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="129"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="508" mass="57553" checksum="1DE8603F5319FA4D" modified="2017-08-30" version="1">MACRRSQVRSLSGPPFFILPRFWRGFLLPFFSPFLPRPAPQTHKHFSHASLISYNNRMAFYKDKVFRLLFVLLALFKAAALLYAAFWNPLGEAVLAFPDSITYVYPAQTWLQYGAMWEAVSATPMLLRTPGYPFFLALIGFFTGNLTWAVAIAQNFLSLFLLIPVYLTARRLAGLPAARWATFFCTVSVLYFSLSFAVLSETLCVFLLAWFVFFTVRFLQAPRAVDLAAAALFLAAAVYVRPAVYYFMFAAAVMLVCFQAGKLVRFPLHKIIVFFILPLILLIGAWQLRNRLQTGFGGFTSVGAYNLYMWNEDYLAHKMGLSVPQAHDALERALPAGFSQLPAQEQVRIYKSWARPLIQESFFYKLSRAPLWALKTLFGANFVHLSRLAWGGRTPQALLEGEMLNHTEAVHTRWLEKFSDKLLFAAAAGQVALTVLLGIIGFWVLWQKEKTSAFFLGVYCLYFWAIGSTFFGAYARFRAPFEFVLCIAAGAAAAALWQRFNPRQRPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMP4</accession>
    <name>A0A1Y4DMP4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F420_ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57580">
        <property type="protein sequence ID" value="OUO57580"/>
        <property type="gene ID" value="B5F75_02055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002847">
        <property type="entry name" value="F420-0_gamma-glut_ligase-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01996">
        <property type="entry name" value="F420_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_ligase" evidence="1">
        <location>
            <begin position="77"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="235" mass="25537" checksum="1BABC09DB8538BE3" modified="2017-08-30" version="1">MKITPVHTRIFKEKEDLPAFIAEHIVLVPEKTVLTVSSKLVALWKGKTVPYTGRTQKEELIRRESQAALQTPLAWLTIKDGMIMTNAGIDESNADGKLILLPPDCYACAQDLRTALRQKWNVQDLGVIITDSMILPLRAGIIGAAVAYSGFEGVKDLRGREDIFGKKLEVTLVDAADSLAAACALAMGEAAEQQPLCLAEGAPVAFVDGTNPAEIKYPPQNDLYTPLLKAVKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMZ7</accession>
    <name>A0A1Y4DMZ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">murD</name>
        <name evidence="17" type="ORF">B5F75_02640</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57690">
        <property type="protein sequence ID" value="OUO57690"/>
        <property type="gene ID" value="B5F75_02640"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="115"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="316"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="117"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OUO57690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="464" mass="50922" checksum="E74287AC0D13D1F6" modified="2017-08-30" version="1">MFRKDKLKGQKACVLGWGKSGRAAAALLAANGFEVLISEEAAISHAAQAVLPPGVTLETGGHSDRIFECGFWIKSPGIFPRHPVLVEAKKRGIPVFSELETAIAFMPKGIRLFAVTGTNGKTTTTALLGEILKENAARENKGRGVHICGNIGSPVSACAPRVKKGDDVVIEVSSYQLEDSTYFRPHYACLLNVTPDHLDHHGGMKGYIKAKAKIFKNQRANDVLVVNGADAVCAQLVEKAKSEVLAFSTQPKHLLKTDVFFDGDELIFSEGHQLRPPHLKGIHNIENAMAAALMAFAAGVPADTVRAVFDRFEAMEHRIEQFAYHRGVVYVNDSKATNLDSTITALKSFDKNRNLWLILGGRDKGASYEVLIPYLKDYCKQVLTIGEAMDKIERELHGAVPLTRCETLDKAVQTAMRGATRGDIVLLSPACSSFDQFKDFEHRGKIFKQLVNAYIFKERTDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN86</accession>
    <name>A0A1Y4DN86_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">yidC</name>
        <name evidence="16" type="ORF">B5F75_03170</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56861">
        <property type="protein sequence ID" value="OUO56861"/>
        <property type="gene ID" value="B5F75_03170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="495"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="YidC_periplas" evidence="15">
        <location>
            <begin position="131"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="25"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OUO56861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="534" mass="59975" checksum="E38BBDFA505AE1B0" modified="2017-08-30" version="1">MNRQFLITAMLFLLIITGYNQFVTIPRARAAQQAAEAQLKKAEQESQRQTAAQAVLASASPVSKETASAPKPEEFFTLSLPQADVTFSSKGAGIKTYLFKDTIEDVDLTPYKGEGYFATLPQVDFAEFARTKNSITFVGDIVPGFSVYKEYRFNDNGINNVSVTFENNTAQALAVSPWNWNFGPGLATVKSEMNDNERESKAVYLVQEKNKKKPTLEVFAKGDKQPELPWLWAGIENRYFLAVLIPQGWKPGDLAASKEKIGTQKRLWGLAGEGTLEGPQFSVGVPGVTVEAKSKETYKSDFYFGPKDYKQFLTLPYHLDRSIAFGFFGALGKIARNILEMFYGWTGNYGVAIIMITVLLQAILFKFTLMQLKSAAQMRKIQPEMKRIQDKYKGNPESLNRETLALYRKYKVNPLAGCLPMLIQLPIFLALYNALRTSWSLHGAKFVFWITDLSSKDPYYLLPILMGAVMYFQQKGNIPAGTDPAQAAMFKYMPLIFTLLFMNFPSGLVLYWLTNSLLTFGIQTFVNKKIAKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNI5</accession>
    <name>A0A1Y4DNI5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF374 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56961">
        <property type="protein sequence ID" value="OUO56961"/>
        <property type="gene ID" value="B5F75_03700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07983">
        <property type="entry name" value="LPLAT_DUF374-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007172">
        <property type="entry name" value="DUF374"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04028">
        <property type="entry name" value="DUF374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="DUF374" evidence="2">
        <location>
            <begin position="70"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="230" mass="26218" checksum="7C8E4E542D82FE18" modified="2017-08-30" version="1">MFRPTSLEKKKISWKHVIGSTLAYWYTVFLGWTTRIYWFKSEEALRFEKEGQNYIFAVWHNQQLFLLYPYRGQKICALISLSDDGEYIARCLPKFGMKAVRGSTTRGGVRALIKLKNIAEAGYHPMLTPDGPRGPIYKVQHGILFLALKTGLPIIPVGTALSHKIKVGSWDKMRVPLPFGKTALTYGKAVYVKSDADMETAALELEKQLNWATDQSERFINHKPFDNTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNR2</accession>
    <name>A0A1Y4DNR2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57031">
        <property type="protein sequence ID" value="OUO57031"/>
        <property type="gene ID" value="B5F75_04075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="59" mass="6345" checksum="33B378A4907F09AD" modified="2017-08-30" version="1">MMGIITILIFVVLLAVPGFYIITRKVFPKGSKKSAMWISILLTILLVGILAAVTATTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPC6</accession>
    <name>A0A1Y4DPC6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57241">
        <property type="protein sequence ID" value="OUO57241"/>
        <property type="gene ID" value="B5F75_00215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="275" mass="29944" checksum="D4D8BBBAA754528F" modified="2017-08-30" version="1">MSETCNHDCSSCSANCSSRNPGEMPKDKPHLRSRIKHVIGVVSGKGGVGKSFVTSLLAVEMTRRGYSCGILDADITGPSIPKMFGMHERATGDQDGIYPVKSQQGIQVMSLNLLLEKETDPVIWRGALITGTVRQFWTDVVWEDVDYLFIDMPPGTGDVTLTVFQSLPVDGIVIVSSPQELVQMIVGKAVKMAQMMKVPVLGLVENMSYLKCPDCGKEIEVFGKSRAEEMGKEFNISPVMRLPLNPAVAQAADEGRIEFVREDAVGPLLDKLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPH4</accession>
    <name>A0A1Y4DPH4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57291">
        <property type="protein sequence ID" value="OUO57291"/>
        <property type="gene ID" value="B5F75_00490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13584">
        <property type="entry name" value="BatD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013028670" evidence="2">
        <location>
            <begin position="20"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="604" mass="65094" checksum="1431BF8E64F92590" modified="2017-08-30" version="1">MKKVCLSVLFFFFAVYAAAQVSITARVDKTALTLDDELTLSVEVKGAAGNMLMPQLPSLPAFNVYSREVEQNTVNGKTTTFFRYVMLPRFVGKATIGAIRFTYNGKTYTTDPITVNIYRNAQGVQRTQPASSTARVASSGNYDSAAVKRPVEKADPNLPPLERNLANQAYARGNENYFLIAAVSDETPYVNEAVTLAVRFYYNRPFYDAPYQKPTVSNIFMEDAGSSQGTQSIGGVLYRYEEQRYQLTAPTAGKATIGPASVRYMTGSSPLSALDRLFGGSAVSAEETAQSAPITLQVRAVPAAGKPKSFYGAVGSGYTISAQADRTQVEAGEAVNLTITVQGPGNLKSTEDLELPSLDGFKTYPAQSVSDTSSAGGSVKSYKIFKAVLVPSASGVYTIPSVKWSYFNPATASYKTIHTEPITLQVSTSTKTDRGFDFGAAAPTGSGFQALGQDIAYLKTSYAPEDSFLEKISVWKTLNWIMLGLLAASVLFASIGRKSLAQKRAYGVAKSQLKKALSDEAVADAVADYLQQKLKISTGSLPLRSIVKSLQQRGITPATAEAFSLLWQRLETARFAPGTPDAQSAQDLARQALDILKLMEEEAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPP6</accession>
    <name>A0A1Y4DPP6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57341">
        <property type="protein sequence ID" value="OUO57341"/>
        <property type="gene ID" value="B5F75_00775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="195" mass="20926" checksum="25E70016BF0C316D" modified="2017-08-30" version="1">MDSFISSVITLALVMDGFGNIPLFITALKKVAPERRKIVLLRELGIALLIMIAFLFLGKWFLHAFGIHEYSLSIAGGIILFIISVKLVFGGEEEPKNDPKEDEPFVVPLAIPLVAGPAALSMVMITAAQQSNKLITLGAVIGASLINSVILMASFPLSKLLGKRGLIAIERLTGMILILMSVDMVMGGISSFMSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQ87</accession>
    <name>A0A1Y4DQ87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Cysteine desulfurase</fullName>
            <ecNumber evidence="5 10">2.8.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogenase metalloclusters biosynthesis protein NifS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_01745</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="5 10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57521">
        <property type="protein sequence ID" value="OUO57521"/>
        <property type="gene ID" value="B5F75_01745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017772">
        <property type="entry name" value="Cys_deSase_NifS_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03402">
        <property type="entry name" value="FeS_nifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="11">
        <location>
            <begin position="4"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="389" mass="42721" checksum="873365A4F2B5361A" modified="2017-08-30" version="1">MKVIYLDNNATTQCSPAVVEAMLPYFSEKYGNASSMHTFGGNNRHVIDQARQQVASLIGAAHADEIIFTSCATESDNTAIFSAVRSYPKKKHIITSAVEHPAIMEPYKYLEAQGYRVDFIGVDEYGRFDMQRFQSVLDEDTALVSVMWANSETGTIFPIAEIARLTHQKGALFHTDAVQAVGKIPVNVQEMDIDMLSLSAHKFHGPKGVGALYVRRGTRFMPYLMGGHQEKHRRAGTENVPYIVGLGKAAELAQKRLTDGTSARIAALRDELEQGIVATIADVKVNGDPEHRVPNTTNISFGYIEGESILMYLNDLGVCASSGSACTSGSLEPSHVLRAMGVPFQFAHGSIRFSLSDQTTREDIELVLKELPPIIERLRKISPFSRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQK2</accession>
    <name>A0A1Y4DQK2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57651">
        <property type="protein sequence ID" value="OUO57651"/>
        <property type="gene ID" value="B5F75_02435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="98" mass="11753" checksum="CD00A95899D4A2A6" modified="2017-08-30" version="1">MKFGQNPKKQWRSSQELDSRFNPLHSRLNQLMILNHVWNRLVGNKSQFWVLKAVKEDTLYVKVKQAVARNELVGYRNQLIAELNKHFETPWIHKIEIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQQ5</accession>
    <name>A0A1Y4DQQ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Divalent metal ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57711">
        <property type="protein sequence ID" value="OUO57711"/>
        <property type="gene ID" value="B5F75_01240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="35203" checksum="3C831FB1E09F7A90" modified="2017-08-30" version="1">MKKYQIIEKKLTETTGDVAQVYVYTNPSVEEQRYLVETCQIDEHTLASALDPDELPRLEFEPEHIVMIYKRPKNYSGKDQLEFKVASVGMFLFEEKLIVVLAEDIPLFVGKRFHTVSSIKEVFLKLVYNSISHYVEHLRIIHMISEEIEDKITESMDNTYLLNLFSLVKSLVYYAEAITSNGFVFEKARNLSARIGFDEKDEEMLDDIIVENMQCKTQADIYSNILAQLLDARASIVNNNLNQLIKKLNVITVWMMVPTLVVSAYGMNVTLPLSDHPDAFWMLIGICLILVWLVMMYWRHKNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA13</accession>
    <name>A0A1Y4DA13_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="7" type="ORF">B5F75_07205</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56053">
        <property type="protein sequence ID" value="OUO56053"/>
        <property type="gene ID" value="B5F75_07205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="126" mass="13871" checksum="70323CB3558ED3D5" modified="2017-08-30" version="1">MPTVNQLVKYGRAKESNRTKSPALQACPQRRGVCTRVYTTTPKKPNSALRKVARVKLTSKVEVTAYIPGVGHNLQEHSIVLVRGGRVKDLPGVRYHIIRGALDASGVENRKQGRSLYGVKRPKAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAF5</accession>
    <name>A0A1Y4DAF5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56183">
        <property type="protein sequence ID" value="OUO56183"/>
        <property type="gene ID" value="B5F75_06085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="97" mass="11051" checksum="D7B8227FB25E09C4" modified="2017-08-30" version="1">MFDKLGQLKDLWKLKSQMEEIKKRLDNMVIKVDSPRHLFEVTISGSQEVKEVRVDALIKNFKEAEIAEDLKAVINKAVRDSQTMAAQTMGNFGMPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAQ0</accession>
    <name>A0A1Y4DAQ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56297">
        <property type="protein sequence ID" value="OUO56297"/>
        <property type="gene ID" value="B5F75_06690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012554025" description="Response regulatory domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="230"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="369" mass="41553" checksum="EA4C4C0B42D05849" modified="2017-08-30" version="1">MKKMPVVLFFFCFLLLAGESRAQNRYTTAMQAIRTGVVSHGSKFSQIAAREFFANPVPLAITQFKTPEAIRSSLVAHGIEESLRKSEQYRENLNKFLEVKKEMDIFLRYQLLEPQKISAAEANARWEYAREGKEALQRMERIVGARDPGVHFGKLYIERVMNAIKPTYAWSGASGKISMPERLRAENSFDVNKFLLKDANGTSLTMKNTSPGSEGFTQARQMAAQLPAMTIAVLNDDPEILEWARNWNAQGFFGPGSRVAVFDSLTKLMEWTKEVKYDVILMDYVLEDGISVFMIDRLRMEGDKETVILVNSALMDDEVPAEDLFEHGADGFISSVGFRADNGGARIANALYNYMQLHGRAALTPHSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAS1</accession>
    <name>A0A1Y4DAS1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56146">
        <property type="protein sequence ID" value="OUO56146"/>
        <property type="gene ID" value="B5F75_05870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="62"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="473" mass="53815" checksum="2E4A9537BEC3E769" modified="2017-08-30" version="1">MQLGNPVKRSKGKRWWRFFSVHYTSGQALNCYNKSMPAGKPDIILTDEFKDALALLEAKPSVKPLIFITGRAGTGKTTLLRYFAEHTAQNTVVLATTGLAAINVHGQTVHSFFRLKPGNLLDKSNLKRLPRKTVDAIDTLIIDEASMLRADLLDAIDYILQLSTHSEEPFGGKKIVLFGDLFQLPPVEEQASGGLFDYFRQLYPSPYFFEAHVLRRLPTEVFELRRIFRQKADPDFARLLNLIREGQVTQPQLDSLLNTRKTFDLPEKFENSIILAPTNREAAWRNVHYLAQLPGEEFTYTATADESFQTKTPPADPVLHLKKGAKIMMLVNDDNWVNGDIGTVYDLGPDFIQVELKGCIYQVEPHVWEDVRYEFNPLLQKLQPKVKGFFKQYPLKLAWAITIHKSQGLTFDSIYLDIGRGAFAPGQTYVALSRCRTLNGVHLKKEISVQDVLCDGRVKQFMDYVRGPHTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAT9</accession>
    <name>A0A1Y4DAT9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">B5F75_05990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56166">
        <property type="protein sequence ID" value="OUO56166"/>
        <property type="gene ID" value="B5F75_05990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="15"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="631"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="839"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="837"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="548"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="551"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="904" mass="102790" checksum="A85B213BADCF01E4" modified="2017-08-30" version="1">MLPKAYEPQEVEQKLADKWQKAKLFAAHVDPAKKPFVIVIPPPNITGALHMGHASTNTLQDVLIRAHRMFGENAYWVPGTDHGGIATQNVIEKKLAKEEHKSRHDLGREAFVQTVWDWYNECGNAIFNQFRKMGWSLDLSDIRFTMDEKRAKAVYECFRQWWDKKYIYRGKRLINWCVRCSTALSDIEVEHEQHAGKLWYLRYKGEDGSDGIVIATTRPETIYADAAIAVNPKDERYKNMVGKKVIIPLANRAIPIIADEAVELGFGTGALKITPAHDATDYEVGQRHNLPIMTVINDKGKMINCPEKYLGMDRELCRKETVKDLDAAGLLVKEEKYNNAVSTCYRCHSAIEPFMSEQWFVKMDKLAQPAIEAAESGALQFHPANWKNPFLNWLKNIQDWCISRQIWWGHRIPVWYCRHCSEKGLTFATDQQGREQLTKVSFEDGAQPIVSYEKPEKCPVCGGHDLVQDPDVLDTWFSSALWPISVFGWPEKTPEMDYFYPTSVMVTGYEILYLWVARMVMTGLDFTGKLPFKDVYLNGIVRDKHGQKMSKSKGNVIDPLDMTAKYGTDAVRFSLLMQAVPSKDIPYSEDSITGARNFCNKLYNASRFILMNMEGIQGPLAMPKEVTELADKWILDRFAHAIKTAREGIEKYNLALTANTLYHFLWGDFCDWYVELAKQRFQTQEKEKVMALCVNILYNTLKALHPLIPYITEEIASSLRPYVAAEGGEFLLQQAYPEFDPALCDKEAVRKMEIIQGVTREIRTIRAQFNVPPALKISAVLTAKDEADLAVVKEYEGYIKLMAKVQKLDIGVNLAKPKQTATAVFENIAIYVPLTGLIDFEKEKKRLEKDLAAAKANIASREARLAQENFIKHAPKEQIEKTKNELAAAKVALAQVTASLEDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB51</accession>
    <name>A0A1Y4DB51_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56423">
        <property type="protein sequence ID" value="OUO56423"/>
        <property type="gene ID" value="B5F75_04305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="519" mass="58175" checksum="2100F24367DD8580" modified="2017-08-30" version="1">MSDKANKRSGMLGTIYNMLPGIDDDYAAKLVYTLEDKKTLPQLQQDIANIAAQLSSDSPMTDTIVAKILLDEITIPAALRQLRIYNNSTSISELCAALEIPAKDTAKLLEVYSSFSSRKYFDEEFASALKDVQDSDMEDAKKALHAVDVLLKQADALLHNSPKTAKQNKKDIFKTADKYHLSVKITAELELLYTQPASIAFQPEFEKLFKSLIAQNPDKHLCASLTAHAMLCQITPKDAQDIALLSKLLNGRILEEDLLIIACRYLKVKAPADIAATFEAVLKKLPHVSSPEENLGLAVRVLLDGTAESFEKASQKASVLREREVLRKALSKKELYSGYEYDLAEHFGGKKTFVQIEREMTDLLNSLPFCSDPKDNKELACKVLLGSLSQEEAAKQAQYLRDLKAQTLTQGLAPELMKSYLGTKPAEELIKFFEESLAPYTFWKSDREKHIFALRTLVGELNGTYNRRISQFVLEMLENGSSLDVMTDMLENIQKKKTSQEELEKLLERYKQARAASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB52</accession>
    <name>A0A1Y4DB52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56424">
        <property type="protein sequence ID" value="OUO56424"/>
        <property type="gene ID" value="B5F75_04310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="695"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="860"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="423"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="477"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="901" mass="97608" checksum="84BB85923E24CC37" modified="2017-08-30" version="1">MRYWVYINDKVDGPYEEDKLVTLQGFTPDTLICAEEIAAGGSQEWVKASSIFEFDQVQQPANQPLPAEEVFNTQTAHSEPLASEKTLRVENAANGDVNKLLLEKIDFLTREITGLQEKLDDMKNKLDAAILSSHYTQPAAAQSYSAPQANDQHTITLTRQDVNEENEDALITNTESLVSQAENIVAAANQEEKPLDMLGPVDLGDKKQDATPTEVSLGSKAEEEVVLRSALDSLYNAKTVQTQEEKESTFQDLLTPQQAKILAEQAAPAPAEEAHKPTLDEALKEVQKADEALTAHEAEKDALLKELTAEPKEDVLDQVIKEREEEKKAETFKMAQAAAVGAAAGVAAAAALHPAEESEKKEEVPGLETVEEAAAEPVEEKKTLDFTDENASPALSIAPDRAEPEKQEEVKPASEMPADVPAEQTPAQTQPDDNMPHLSVLPSSDEMPGKTAAPAEEDKKGETVQELVPGAKTEKPDGVLITEEDLNEAFSERNNDSNQSVEQLFGLAPEQTSDKKEEAPAPASQEPQTLPQFSDQTADKPLPMGNPNDLTEIELKEGSTYLISDFVPPAQTNGNELPKEISKLDAKPVEEKVPQQNAQETKPAEVQEMVSPLKQTEKTVEAAADAPKDVTVSQIILENTIKTKRGATLDIKTVPMVPEPAQSDRLHLDNMDDDLNTQHDLKAADVKPAGKTTKLVAGTLVTVVLAALIYVMLAFMNLIPPQFNLLSSEPTAQQVAEQNAQMDEMLGTQAQPAAQPAAQQTPAANPMDTVLDEVKNYPLMNGYTLKQFIEAKHPAAKDLITWDISTAVDPDNYSVLVKVPPENPQSFKISYRFNYNTVTKALDPTISDAKNLLDSAAQGAALPQQPAAQQGQPAMAPMQGGNMTPQPAPAQAAPVTSTVQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB93</accession>
    <name>A0A1Y4DB93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the OprB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56444">
        <property type="protein sequence ID" value="OUO56444"/>
        <property type="gene ID" value="B5F75_04420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007049">
        <property type="entry name" value="Carb-sel_porin_OprB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038673">
        <property type="entry name" value="OprB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04966">
        <property type="entry name" value="OprB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010897583" evidence="2">
        <location>
            <begin position="24"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="412" mass="45496" checksum="E90371B1D66EC840" modified="2017-08-30" version="1">MKSLKKWGAVLALMGICAAICFADEARAATSAQTSAKHEQRQLARQRVENHSFSDFGSKYIEAKKFLTDKLGLQVGLDISYTAQRVAPGGKQTAIQGIYYPYVTWTLFQDRAWGSGALNVNYNYIHYWGQQAEVLQDRANLVSAINDYDANQYFFSQFTYTHTLPGKWDWLSVTAGQFPLYNFDGTEYVDNQQTGLMNYALSQNASSAYPLASLGAYVQAQNSRFTFAAGYQDATNITGAEIHGKTAFDGKYTGFGSFAWTPSFKWGDGQYSFLYYYQPAVAQQDENVNGWSFNMQQNIGSKWALFGRANGSTGGAVPIKNSYVLGISLLNPLGRNPQDVITLGAAYNRLSPAGAGYPPFLRSGETVIELQWVWGIGKFVTVTPDIQFYPRAGFSPDQGVTTVAGLRTTVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBA8</accession>
    <name>A0A1Y4DBA8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56447">
        <property type="protein sequence ID" value="OUO56447"/>
        <property type="gene ID" value="B5F75_04440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012870329" evidence="2">
        <location>
            <begin position="21"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="102" mass="10744" checksum="CC4A57745ECDA77E" modified="2017-08-30" version="1">MKKMMLFAAAAVLAAGCASTGTTSSTGTAQPMTLEQALQKSAETRQKLLDAKQSYENAKAAAEVASGQKTAADAAKEQLQQKVDNAKQQIQAEKDAWAELLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBB8</accession>
    <name>A0A1Y4DBB8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56464">
        <property type="protein sequence ID" value="OUO56464"/>
        <property type="gene ID" value="B5F75_04530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="408" mass="44083" checksum="6DCBA2C4CECAE272" modified="2017-08-30" version="1">MNSPIYDVIIIGGGASGLMCALECARRGKTTLLLEKDALPARKILVSGNGRCNLTNAHVSPSFYHADTALMAQTLSQFSFQDCLDFFARLGVLTVEENLGRVFPSTGKSTAVAEPLKLAVSEAGAEIQTSCEAVRLKRGKTFTVHCRGGQIFQSRRLVLACGSCAYPQLTGTQSGYELARSLGHSIIPPKPALSALCLKETAVARLNGIRSQVRLRALQNNRVLDQAEGEVLFTNYGINGPAVLNVSSSVSRALKDGNVVLELNFLPQLKDPQNFLRQRLAAFPARRPKDFFAGILHESIANLLIDFIGLRKNIPVGQQTPNALQRLVQTPCAWPLTATGVRPWNEAMAATGGVNTREINYNTFESLKCPGLYITGELLDVDGKSGGFNLHFAWASGIIAARALSEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBC4</accession>
    <name>A0A1Y4DBC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56474">
        <property type="protein sequence ID" value="OUO56474"/>
        <property type="gene ID" value="B5F75_04580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="128" mass="14427" checksum="3CEB7D9B8230B377" modified="2017-08-30" version="1">MKITFEGNKKVKVHVKNFDIMTDQSKEHGGDSSAPTPIDLFLASLGSCSGVFVLNFLKQHNLPETVYLTLEPEWNINEYVIDKIKVFIHVPPDFPAKYENALVEVAKRCLVARHVKITHEISVVHEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBH7</accession>
    <name>A0A1Y4DBH7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56225">
        <property type="protein sequence ID" value="OUO56225"/>
        <property type="gene ID" value="B5F75_06295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="73"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="141"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="326" mass="36864" checksum="79F3CDA42CC78654" modified="2017-08-30" version="1">MYLNRNVILLVTGLLFLGGCSATQTGILGLAPAGDRKEYVQARDLYSAGNYPEAIRHLSDYIYKTKNVKRREARAYRLLGMSYEQLGQLSKALEVYLEALEFHPSNVPLLLAAASLYQRTDLTDRSIELYEQVLALEPNNLEALSGQGANYSKMGFYSKARSFYDKFFELNPSAAPIYRARYAETFLRQRNYKDAFTHITMALAEDNSSADFWLLSAKAARGLGRPQEALANLEAALLLAPQRRDLLANKALWLYEAGRYEASAQTARQLLTQYPENQLAVLILAMDAYYLGDKKESRRLMQRAFKEDSDSFTGQVAGKLLKQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL9</accession>
    <name>A0A1Y4DBL9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56255">
        <property type="protein sequence ID" value="OUO56255"/>
        <property type="gene ID" value="B5F75_06450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="395" mass="44881" checksum="307D9D196DA176BD" modified="2017-08-30" version="1">MNWQDPDVQQRIAEWQQLLDWRGRDSRLVRGAFAWSRWKKKFLNTLKWRLRRKKTPAETDSLRVLFWLPGGLGDAACAKRLVTAYRFFLPQARFDIYAPLPGVAKMLFGADKNTRILEKDDFSPFDYDLALQACMAVKFLQVTPERIECLAPRFGEVVRRAEEAQKSLGSLLDDVFLTEGVLGRWLYEQGARRFELLSYTGGVELPHDAQEQLQTDAEPRRKWGLEGVKYITFHDGTSEAQVMAHVRPTRAWPAVRWCEFFRLFKKEFPQIKLVQLGGRNSPVYEEADVCLVGKTAVAELPSLLAGALAHLDTESGLVHLAQFLPVRSVVLFGPSSAHFLGYAKNENLDCGPCGGCMWITPDWMKRCPLGHEPAPCVERITAQAVLAALRRILPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBM2</accession>
    <name>A0A1Y4DBM2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rubrerythrin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56537">
        <property type="protein sequence ID" value="OUO56537"/>
        <property type="gene ID" value="B5F75_04915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01044">
        <property type="entry name" value="Ferritin_CCC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039376">
        <property type="entry name" value="Ferritin_CCC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="288" mass="31630" checksum="A001D2F04FD6E9FC" modified="2017-08-30" version="1">MLAETKNNLEVFSRNEITEYHIYKQLAAREKNEKNRRVLETLSTDEKRHYDLIKSETGVAAVPDRFKIVWYSFLARTLGLTFAIKLMESGEHHASGTYRAFTEYPRIAQLAEEEDAHEGKLIALINEERLAYMSSVILGLSDALVEFTGALAGFTLALSNSKLIALTGAITGIAAALSMASSEYLSSKTEQDAGKHPVKAAVYTGGAYVITVALLVAPFACLNNVFAALGLMLFFALLLIAGFMFYYSVARGENFKHRFIEMTCLSFGVAAVSFLIGFALKTFTGIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR2</accession>
    <name>A0A1Y4DBR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_05225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56594">
        <property type="protein sequence ID" value="OUO56594"/>
        <property type="gene ID" value="B5F75_05225"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="315"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="152"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="251"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="435" mass="47746" checksum="C4EA173D75C25EED" modified="2017-08-30" version="1">MKIGIIGTGYVGLPSGVGFAELGHTVVCVDNNKAKIEALNKGKLTLYENGLADLFKANTEQGRLRFTTSMKEAVQEADLVIIAVGTPPDPITHEADLQYIYAAATELADYLTGYTVIANKSTVPVGTGDAVEKIIASKNPAADFDVVSLPEFLREGFALQDFFNPDRIILGTHSERAISLISKLYEPFKEKTPLLVVSRKSSETIKYASNAFLAMKIHYINEIANFCEKSGANVAEVAKGMGMDKRIGNRFLNAGIGFGGSCFPKDTMAMAHMANKVGVRMELIETTIAGNQKRKKEMADRVYQSLKDLKNPKVAVWGLAFKNGTDDCRQSPAMDIIRELLQKALSITAYDPKAMDTAKAILGDKISYASGMYEAVKGADVLVILTEWPEFSAPDFDELAKRMNRKVIFDLRNMLSCEDAQEADFEYHCIGRKCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBU1</accession>
    <name>A0A1Y4DBU1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoC</name>
        <name evidence="10" type="ORF">B5F75_07200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56052">
        <property type="protein sequence ID" value="OUO56052"/>
        <property type="gene ID" value="B5F75_07200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="9">
        <location>
            <begin position="242"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="833"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="914"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="921"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="924"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1392" mass="154396" checksum="C15F29B9B75B5D65" modified="2017-08-30" version="1">MQQTKKVKKLNELNFFDFDAIKLGIASPEQILAWSYGEVKKPETINYRTLKPERDGLFCERIFGPTKDYECACGKYRWVKFKGIKCDRCGVEITESKVRRERMGHIELAVPVAHVWFLRKNPSRIGIMLDMRTSDLERVVYYAAYVVLEDCVDSVTGRVDFKKGTLLSDVQVREARKKHGARLKVGIGAPAIKTLLEGIDFDKEIPALHEQLKNTQSEMERTKLIRRIKTMEEFKESGNRPEWMILSVLPVIPPDLRPLVPLDGGRFAASDLNDLYRRIINRNNRLKHIESLRAPEVMIYNEKRLLQEAVDALIENGARGKFFIGPGGRPLKSLSDSIKGKHGRFRQNLLGKRVDYSGRSVIVVGPNLKLHQCGLPKLMALELFKPFIIGELMKKEGVTLKSAKKMLERVRPEIWDILEKVTKNHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLTCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNILSPASGKPIASPSHDMVLGVSFLTKIKDGDIGEGSIFGSKEEALVALEYGKLSYHAKIKVRGINAIVEPGLDGKEEKDPSKWKDFTSVGRIIFNQALPKGWEYINKTVGKKELAALVDECYKSKKYGRYEAVQLLDKIMKMGYHYATLSGLSISIADMTIPSAKQKYIDDAKKKVKEIQAQAEAGIITEGERYNKVIDIWTRVTDDVANELFKEMKKFEESKYDPTNKEHSGQRFNSVYLMADSGARGSRQQVRQLAGMRGLMAKPQKKLTGGQGEIIESPITANFREGLSVLEYFISTHGGRKGLSDTALKTADAGYLTRRLVDVAHNVVITEEDCGTHNGIVVKSLMSGEEMVEPIEERILGRTSLEDVVVKVKKADGTEEEKTIIKEGDLITLEQSKLVKKYGVESVRIRSVLTCEAPYGVCAKCYGLSLATSSKSNPGDAVGIIAAQSIGEPGTQLTLRTFHIGGTASRVLSRSQAVAEIDGKVTFKDVKIITNRYDNKICISRNGSIFVEAGNGTIKEYKIQYGASVYTADKATVKKGTLLAEWDPHSIPVLAEAPGTVRLTDVIEGITLQEERNKVTGVIERKITASRMGKKNPRISIEGKDKKVSLPLPIDTILMVENGEEVEPGDVLAKIGREAGGTKDITGGLPRIAELFEARRPRNPAIISEFEGIVSLETSPKGLIEVVVRNEETNQVKQYSIPQGKHLVVYEGDHVGVGEALTDGAIDPHDVLRVKGEKEAQEFLLNAIQEVYRLQGVTINDRHIEVIVRQMLGNVKILDAGDTHFLKGEILSRASWLRENAKMKAEGKRLADAETILLGISKASLASESFISAASFQETTKVLTDAAITGQVDELRGLKENVIVGHLIPAGTGISARKIAEEFNQKRKETGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBW5</accession>
    <name>A0A1Y4DBW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56644">
        <property type="protein sequence ID" value="OUO56644"/>
        <property type="gene ID" value="B5F75_05490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="39850" checksum="02E1E2D1C1D766A7" modified="2017-08-30" version="1">MKIDDKVDAVYIPDSPSRIKATDYNQIKNEIQECITLAGLTPTKDVIQLPEALKTLTQQSGAEEVAKIEAAGQEQTSSINSTGATQVQAVNAAGEAQKTLVENTGMTQIFEVQAAGERTVSLVEQAGADAAQLAKDWAIKTDGPVASGEYSAKKYAQDAAQSATAINPDTYVKKAGDTIAGILQINAVGNELRFIHPDYPDYLGFIRRSNESLVIGTKNSAGTWLKSLTITDASVSASVPSPDANGNEVATANWVRNLISGQTLVKDYIIDSYSDDSGNWYRVYKSGWVEQGGYVSAVAQDYQTYVHTFIKPFASTNYFFKHIYITNNVTTSPIYLMNISNPTTTSVTLYNYANFVTGFKWYACGQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBY5</accession>
    <name>A0A1Y4DBY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56566">
        <property type="protein sequence ID" value="OUO56566"/>
        <property type="gene ID" value="B5F75_05070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011966236" evidence="1">
        <location>
            <begin position="20"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="385" mass="42417" checksum="8CE5BBDD0E312BC7" modified="2017-08-30" version="1">MKKLLGLLLAMTMAWPINAAIVDNVDAIGEIEVIGANNNAQKSEANGAASRVMAGLSAELTEDVRANVQFVYNTAWDGAEKGKDLNTYQNQIYLAEANMVLSNLMDRFELTLGRQFYGDEDSALLYFGPRHGYMAALSSPVTSLDAAKLTYADDVKALTLIAGKTTKVLTFDPQTKSNADFYGIDFRMNLTDTVKAQVYGYTYKNNVWNDEFQGFYGAKLSMMPEAGALSVEYARSHSGDRLVKESHDNPYLVKVDGSLNMDAFTPRAAFIYQKGTVSEYGAYAPGLVYGKTFFGNDLTDVLSESRIFNVGLDYNWEKWTLALDGFAFQDRTAQHAATLEADLTATYQHNENVGLFAGIGYAKLSRADFDRSDATVYQAGVNVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC56</accession>
    <name>A0A1Y4DC56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative septation protein SpoVG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">spoVG</name>
        <name evidence="6" type="ORF">B5F75_05445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Could be involved in septation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SpoVG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56636">
        <property type="protein sequence ID" value="OUO56636"/>
        <property type="gene ID" value="B5F75_05445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00819">
        <property type="entry name" value="SpoVG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007170">
        <property type="entry name" value="SpoVG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036751">
        <property type="entry name" value="SpoVG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38429">
        <property type="entry name" value="PTHR38429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04026">
        <property type="entry name" value="SpoVG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160537">
        <property type="entry name" value="SSF160537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0717">Septation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="111" mass="12648" checksum="AF65E0D496E0C8E2" modified="2017-08-30" version="1">MKITEIRIHLMGEDRLKAFASVTFDDSFVVRNMKVVEGTKGVFLCMPSRKLPDGTHKDMVHPINQEFREYLEQNVLKAYEEELKKNPEGIQKTSGDSNYNLNAAESGQDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCE5</accession>
    <name>A0A1Y4DCE5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56262">
        <property type="protein sequence ID" value="OUO56262"/>
        <property type="gene ID" value="B5F75_06505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="100"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="134"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="203" mass="22099" checksum="8A49CFB526FDEF71" modified="2017-08-30" version="1">MKMSTVVTVLIVIGILCGGLYLRYHNKDTDARGATRLMRSIENHAELNDTVKLIEKSEDINIRDKSGKTALFYAARAAQDPQVVRDLLEAGANLHIADENGQTALMVAAQYNPSVDVLEEFTKNGAHVNAADNEGNTALFLAAQYNNAGIIKSLLRAKADPDLPGPEGKTVAQALAENPQLSDQEKTDYRQAMLVLSILQPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCH6</accession>
    <name>A0A1Y4DCH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56807">
        <property type="protein sequence ID" value="OUO56807"/>
        <property type="gene ID" value="B5F75_02890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015067">
        <property type="entry name" value="DUF1893"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037081">
        <property type="entry name" value="Hyp_TM1506"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08973">
        <property type="entry name" value="TM1506"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011003420" evidence="1">
        <location>
            <begin position="22"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="166" mass="17876" checksum="33BF15801D4A5B93" modified="2017-08-30" version="1">MQKLMSLLTGCLLLCACSAVSQRTVSQEELLALAKGHDLVAVFPDGRVETYNGRGLGPLLKHLETGNLKGAQMYDKVTGRASALLLAYGGAASLHTGMLSKEAIPILKKYHIAYTADKEVDYILNRSKTGSCPMETAARPLDDAQQAFPILKAGFEELTSQNYTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM8</accession>
    <name>A0A1Y4DCM8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56352">
        <property type="protein sequence ID" value="OUO56352"/>
        <property type="gene ID" value="B5F75_06985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="247" mass="27284" checksum="E2748B56AB6DA107" modified="2017-08-30" version="1">MLLTLLFTGAAFGYEFQVSPVAKEGPLGKKQHRMDENGEYECGVLLINTKIPNIKFNLSGIGGCGVEKTKRGYAVYLGRNTTYLTLTAPGFKSLRWDLSLPGGIQNQQYTAKIAVFGQDPATFSDSNTLKGVFKQNETGLYSRFAGKGKTLLKINTDLPFATLEETLLRPGSYAVRGEQTAAPYYLLIPSGTALGQVLRQERLAGKIPWDTVLKAPEDYQLDLSWGTEQDPNQLLKEVKKQVRVKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ3</accession>
    <name>A0A1Y4DCQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56944">
        <property type="protein sequence ID" value="OUO56944"/>
        <property type="gene ID" value="B5F75_03615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033563">
        <property type="entry name" value="UCP033563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="413" mass="46958" checksum="740B702DDE5E4794" modified="2017-08-30" version="1">MATIKPFRGFRPSAHADKIACPPYDVINSAEARQMAQGNPYSFLHVDKPEIDLPEDVSLYAQEVYQKAKDNLEHFLQTGVLKQDEKPCFYLYAQTMDGRTQYGLVAVASCEEYDKDIVRKHELTRKDKEDDRTRHVATLSATTGPVFLTYPARAEIDEKLAQIASEFPVYDFTAPDGIKHTFWVIDDLQDIRFLQDAFAQIPTLYIADGHHRSAAAANVARQRKAHNPKHTGQENYNFFLSVIFPANQLYVMDYNRLVKDLNGLSKTDFLSKAAQKFDVAETGREKPQKRHEFGMYLDGKWYTLTAKKGSFDDQDPVAALDVSILQENLLGPVLGIGDPRTDKRIDFVGGIRGIGELKKRVDSGKWKVAFSMYPTSMEELMKVADAHKIMPPKSTWFEPKLRSGLVIYKYEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCQ9</accession>
    <name>A0A1Y4DCQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-ACP thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56903">
        <property type="protein sequence ID" value="OUO56903"/>
        <property type="gene ID" value="B5F75_03405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:acyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045023">
        <property type="entry name" value="FATA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727">
        <property type="entry name" value="PTHR31727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="242" mass="27576" checksum="71E0F5E287F0599A" modified="2017-08-30" version="1">MLEQIFHVRFDELDAAGHIPAVTFLKYFQQAAALDSAQSGFGFDDLHPQNLAWILTHMQVRALQKDVPLQPVTLRTWHAFSDKILSRRQFVAYGKDQTPLFEGSSWWAIMDIVKRRLTRTPAQLLSVRAPEADALEPEENFKAPLPAAAPAATLEIVTREEDLDLNAHVNNTHYAAWAIQSVPPSARQDRQLDRMLISFKNECRAGEVIRIGVYPCEENAFWHTLVRASDGKEAARVYTRWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCR6</accession>
    <name>A0A1Y4DCR6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56913">
        <property type="protein sequence ID" value="OUO56913"/>
        <property type="gene ID" value="B5F75_03455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="21"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="244"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="331" mass="35927" checksum="C3BEE19A65CEA32B" modified="2017-08-30" version="1">MENREESLQQIWQAIRAGKRFFIAGHLNPDGDSLGCTLTMTSLLERLGKTVYAYAAPAIGNDLKFLPGLSKIHVGVLPEQPDFDTVILLECSDRQRGGDLESVLGKAKTLVNIDHHLVSDAYGDVNHIDSKASSTAEIIFQLFEASGEAHCLPTPDEATCLYTGLVTDTGRFVHSNTTAEALRVGSALVALGANVDKINQVIYFTKSYIELKLLGRALEKMEMRFDNKYSQIILTRRDFESFGATPAQTQGIVSQPTMIPGVEVSALIKEEPDKVSVNLRSRGGVDVSKIAQTFGGGGHARASGFKVTGKAVNEVADELAQVVYDVVKDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCV3</accession>
    <name>A0A1Y4DCV3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Arginine:agmatine antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56442">
        <property type="protein sequence ID" value="OUO56442"/>
        <property type="gene ID" value="B5F75_04410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004754">
        <property type="entry name" value="Amino_acid_antiprt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00905">
        <property type="entry name" value="2A0302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="284"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="484" mass="51997" checksum="E7E9C5E6BE9D42CC" modified="2017-08-30" version="1">MGDKNNTATKLGVIGLASIVISSMVGGGVFSLPQNMAAGASAGAVLLAWVITGIGMYFIANTFSILSRVKPDLTSGIYMYARQGFGPYVGFTIGWGYWLCQIFGNVGFAVITMDALNYFFPPYFAGGNNLLSIVCGSVLIWVFNFVVLRGVKQAAVLNIIGTIGKLVPLLLFILILLFSFHMDKFDFNFWGHMAEGGKTLGSLPEQLKSTMLVTLWAFIGIEGAVVLSARAKSQAAVSKATFLGFLGCLVIYIGLSVLPFGFLTQEEIAAVANPSTAGVLEKVVGPWGAWVMNIGLLIAVLSSWLAWTMIAAEIPAAAAENGTFPKQFAIQNKNGAPSVSLWVTSIIMQLAIFMVYFSNNAWNTMLSITGVMVLPAYIASTAYLWKMTEDGEFAKISSTGRAAALFTSVMGTLYGCWLVYAAGLKYLFLAVIFLALGIPVFVWARRQQKDGKPVFREGEVAVVTLLIVFALAAVYVFSRGLVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCV8</accession>
    <name>A0A1Y4DCV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">B5F75_03145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56856">
        <property type="protein sequence ID" value="OUO56856"/>
        <property type="gene ID" value="B5F75_03145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="216" mass="23384" checksum="44476E747B93A5D9" modified="2017-08-30" version="1">MQKQLIDFAARAGLPLSAEQADRLVQYAKLVWEKKDFLNLTSASSLEEILSRHICDGLTAAAKIYAMAHIKNLSSCHAADAGAGAGYIGITLAVALPQAQVTLIESLEKRCSFMNWALLQLGLSNAKVKKVRLGQGTKFAFDFLTERAMGQLPDILAACLSAVKPGGVFIAFQGEHPQTDVCDPHACGAVLLGVERYSLPCDDKKRHLALFEKREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD14</accession>
    <name>A0A1Y4DD14_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56512">
        <property type="protein sequence ID" value="OUO56512"/>
        <property type="gene ID" value="B5F75_04780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="127" mass="13884" checksum="ADAFE258ED24A9BA" modified="2017-08-30" version="1">MAIKTVLGDNLQTKSVLEGKTGEVRSAYLDPREDMQPGELLAAALGACMLTMVGFMASKRGENVTGTELHVTPGFDEKHSRVTSMALSFVFPASLTDEQKKFYARAAQSCPVHNSLREDITYTVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD60</accession>
    <name>A0A1Y4DD60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57017">
        <property type="protein sequence ID" value="OUO57017"/>
        <property type="gene ID" value="B5F75_04005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="76" mass="8991" checksum="5D793FE986DEC545" modified="2017-08-30" version="1">MNTEKIHHWIYLIGVACAVLFWCFTMYGLPPRVDKLEERVREHDRKLAESTVKIDIILDDVKTIKTHILNFHGRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDD2</accession>
    <name>A0A1Y4DDD2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56652">
        <property type="protein sequence ID" value="OUO56652"/>
        <property type="gene ID" value="B5F75_05530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="113" mass="12687" checksum="8B5232CF21332E6E" modified="2017-08-30" version="1">MSFGSLLNDTCNIYARVESVDEETGEQIFTQELAAENVPCAFQNGSGALDRSGRLVTGSNTDRLYLFPPDFEILKTVHIVEVRGAKFRISEVKDMGGRKRYLRLDLERVALDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDI9</accession>
    <name>A0A1Y4DDI9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56935">
        <property type="protein sequence ID" value="OUO56935"/>
        <property type="gene ID" value="B5F75_03570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039369">
        <property type="entry name" value="LacA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43017">
        <property type="entry name" value="PTHR43017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="5">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="22253" checksum="F265D0EA4A707477" modified="2017-08-30" version="1">MNQKERMLAGLPYRASQDGLPQEQIENKQKIYDYNHCRPNETQKMKQLLGSMLGRCGQNVTVLPPFYCDYGKQIEMGDNVFINYNCVILDVCPVHIGDNTLFGPNVCLAAAGHPLHPLSRRSGYEYGAPIYIGKDVWLGANVVVAPGVSVGDGSVIGAGSVVVKDIPAGVLAVGNPCRVLRAITEEDRPFYFKKKRFDVSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDK0</accession>
    <name>A0A1Y4DDK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56945">
        <property type="protein sequence ID" value="OUO56945"/>
        <property type="gene ID" value="B5F75_03620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="182" mass="19855" checksum="869805AD67AB91D2" modified="2017-08-30" version="1">MAKIYQKSFPGGKNAGFTLIELLVVVLIIGILAAVAVPQYQKAVEKSRAAQGIQMLGSIYEAQKLWYLQMGGNINNSGVNEWEDLSIDLPCNSKGTSGPADNHVLTCNSNFFTYTLGGTGGGGRVWYQNWAFHPNAVTPDYVLGTEEDKTFFCCSSEAQKCRNIGMTKPRGKDYASGVPCYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDM1</accession>
    <name>A0A1Y4DDM1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00070</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57213">
        <property type="protein sequence ID" value="OUO57213"/>
        <property type="gene ID" value="B5F75_00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="371" mass="40649" checksum="9D05B3AF450EB602" modified="2017-08-30" version="1">MKLRARTLKGFFVKEIIQIIRDPKMIMAIFFIPVVQTIMFGLALTSEVKNIKFVVASKPGKIAQDLETRALASGWFTKVPDVNGAQVEDPEALVASHKAEAVLVAPPEGFEKALERGSEPIQLLLNATNAQRAQQVNGYVQQLVAEVARANGYNLSGGLIKLDMRVLFNHYMDTTSFMIPALLVMSTFIVLLVVGGMAIAKEKETGTMEKLIVSPCSVEEIMVGKTLPYFVIGLCIVGLILFIGVAGFGIPFRGSLWQVAVNAVLFAVSALACALLISTVVHTQQQAMMASALFLMPAILLSGVFFPVANIPPLFRWMCYLNPMMYSVVNFRSIILKGGDAWFFWQNCLWLAVISAVLCAAAYKNFKSKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDQ2</accession>
    <name>A0A1Y4DDQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57227">
        <property type="protein sequence ID" value="OUO57227"/>
        <property type="gene ID" value="B5F75_00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="2">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="412" mass="45056" checksum="56E6C58E356C2143" modified="2017-08-30" version="1">MKSVIITIGDEILLGQILDTNSRFMARELAKLGAETVQMRSVADEKEAIWKALDDAFCVADAVFVTGGLGPTKDDLTKNVLAQYFGTELVFNPQAYAWLEEMFSANPQRLNAYNKSQAMLPRACTPLHNVKGTASGMWFEKEGKVLVSLPGVPFETEYLFPAEVLPRLKEKFHDLLLQYRMVTVYNIPEAELAMRLASYEQKLPKGLSLAYLPSAGFVRLRLTAKGAAVERLDTFWTALLQELKGLSFEEPRSETSQEEFARRLRQSGVTVACAESCTGGNIAHLITAVPGASAYFLGGVVAYSNEVKKQVLGVSEEDLKKYGAVSEPVVLQMAQGVRRITGAQWAVSTTGVAGPDGGTPEKPVGTIWMAVAGPNGARAQKFVFSHTRERNIGRGSIQALQFLLNEIEAANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDT6</accession>
    <name>A0A1Y4DDT6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57284">
        <property type="protein sequence ID" value="OUO57284"/>
        <property type="gene ID" value="B5F75_00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="312" mass="35162" checksum="0269DD85F8B13F06" modified="2017-08-30" version="1">MKLKIKNSTLAAASPLYIFVYILLALIALFVLQWLLSHLQPVTAVWKDLLAYARGKSLLSYAFIYIFPWLAGLWVVLFFCSRATRWNKARKTNPIVFLSFEETGVLLGHKNPRADRCLPYAETDLSVCLPVFVTYNKYGQAFAHLAELEIAFSQTGKTYSVRHKGKLPFVQTLLDEGKKFRTASATVRRLETDKLPSQSETNFIHFLEEQLENHRRYGQMLPEYPAPRAVWLVLGLTCLAVIEWGIGMALSVFLKTNASPVLLALLCVLAAGPLVWAVWNIQRYRAFRAASQKLQTLKNASSAAEGGTATRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX8</accession>
    <name>A0A1Y4DDX8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57323">
        <property type="protein sequence ID" value="OUO57323"/>
        <property type="gene ID" value="B5F75_00670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="515" mass="58422" checksum="56DB1BBB53C6B06C" modified="2017-08-30" version="1">MKKYLVLAVLLAAAPVWGLSLSKENKQEARLFNQFLKAVYAQREEDPRAFSYLEKALEMNPSSKYLKRLLVSEALAQGNAAKADAYASFIQEGENEAEDWMVYAAYQWKKGNLSEAETAYEKALKLEPDNTRILYQYVLLLTVTNVDKAVSKLLPLAEEYPALKSDVYTEIGTLYLRIKDLNQALVYYNKAVEADPSNPEARLGRGEVYEKASQYFLMLHEFEELEKMGYANADTLSRMASVFLMANDVPKAEAYFLKAKADDNGDVPSAYFLALIAEQKGDFSRAIGYLKDSADYDRSASKWLQVSFYQQRLNQPQESLNTLEQAYKKFDGNVEIAYFYALALNEVQEYKKAARVLKKLLDSNPAYEDARLQYAFTLESLKKYKEMDAQLERILEKNPNNAPALNLYAYSLANRNIRLEDAQEYIARALALAPEDNSFIDTQAWIYFKQGKLQAAADLLAAIAPETVASDVEISYHIGAVLCAQGKTKEARPYLERARGKIKEADKLYKKILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY0</accession>
    <name>A0A1Y4DDY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57246">
        <property type="protein sequence ID" value="OUO57246"/>
        <property type="gene ID" value="B5F75_00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="284" mass="32467" checksum="B8A1BAB806C18BCE" modified="2017-08-30" version="1">MRKLLPFFLLLLLIAAWAVFFDRATDHFIFEPSRQIYSLQTPFEEVSFPAKDETPLYALYHKADPGKPTLLFFHGNKYNIYSFQDFALPYTQKGYGLFIFDYRGYGKSAGRATETHMYEDAESALFYLTLKQNVHPKDIVLWGVALGASPALYVAAHYNKLPFLGVILQSPFTNITEMGFYMLAQKYDETPAATILPLFLKPILWNKDFNNTQMIENVRAPLLIGASQMDRTIPWTMSRALAVKAPAGTRKFFPSLGAHHNPEWMEEEALAFLNQLETKTPDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY1</accession>
    <name>A0A1Y4DDY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_03125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56852">
        <property type="protein sequence ID" value="OUO56852"/>
        <property type="gene ID" value="B5F75_03125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="65"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="251"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="564" mass="62851" checksum="F52BE8FAA7630E0E" modified="2017-08-30" version="1">MFKRKSGSPFVFNVKNRMRVAGLVILLAPLCIFVRLFYMQTFLYEEFSSKAERAIYNYLAEDRLRGKILDVNGRELAESVRTHSCGVNKRYVQDKNKTVAFLAETLEMPKRRILEKWNRASNFFFVAKKIKPDKYIKISQILRTRLGQGLELTPEYERIHPYGSSAIDLIGASNSKNFGLSGIEQMYNRELSQDISKKRAKRARRGEIIYDRKLKEELSVANVYLTIDAVAQFYAESALKKEVEAIGAKHGIAIVQEPKTGKILAAASYPAKDGQSLAFQFTYEPGSTFKSIAISSALDAGVVHITDQIDMSDRKWEVARGVVIRDNQHKKDFLTIPEILQLSSNIGAGKIALELGAKNLFYYLKAFGFGTKTDINFNGESKGNVPPYSRWTVVDTASKGYGYGVAVTPIQLINAYSAIANGGILMQPHIIDRIEYAGGKVDVKSKPVKIRRVLKEETTEVMKKALQSVVEVGSGKRAQIKGYNVAGKTGTAEKLSKEGGYAKRQHIVSFCGFAPVSDPQFTVLVVLDNPEKYSFGSSTAAPVFKEIMERMLAMKGVAPDQTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY5</accession>
    <name>A0A1Y4DDY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57333">
        <property type="protein sequence ID" value="OUO57333"/>
        <property type="gene ID" value="B5F75_00725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="523" mass="60304" checksum="4D6776DABBF46967" modified="2017-08-30" version="1">MTIQDQVLSSRLNGILLPLSAMKTAGDWGVGDFSSLREWTEFLAAQGAKIIQILPLQETAPGENCPYSALSAFATDPVYADISNVPDVAASPRAQEFIDSISFKIREWHDAPRAPFFAVKQAKLKALWFGYQYFLETQAAANSPRFQAFEAYCAAQAGWLRGYALFRALKEFYKWQTWTQWPEGLRNFEPSAVRAFEAQYREYVHYFSYMQWILDQQLRQAKTFAQEKGVLIFGDIPFGTNLDSAEVWSERANYRLGWEIGAPADQFSKGGQRWGLPAYDWVYQHSHNLDLWRRKIRRVTELYDIFRLDHLVGFFRTYVFAPGDQVGSFDIQGEQNQIDRGYNFLRMVLDEAKGKLPVGEDLGVIPNYVRRMLADLRIPGYKVLRWEREDNGYYREPRNYPQVSLATTSTHDTETVRGWWETMDVHERANIWEMISAQKTDGNVPFNDYSQRAILRRVLDSNSAITLFSWQDIIGTLDRVNTPGTVGENNWTYRSAYTPAQAAQVYAPQLATYRELLKETGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDZ3</accession>
    <name>A0A1Y4DDZ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57266">
        <property type="protein sequence ID" value="OUO57266"/>
        <property type="gene ID" value="B5F75_00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="344" mass="39822" checksum="2D24A9782063060F" modified="2017-08-30" version="1">MGCFMSCDWQYTAQQCAENRRRINLHTELASPRKTAVVLTCSRAFTFCTYVSVDSFLRHSPQLAEQSDIFVFIWQADDKLRQIFTSLSDRVQVVDFDMPYPVPARKSITLFTPASYARFECFRLLDRYERVLFLDSDVLVRKELAGVFDQISNGIGITLDPVMTTVARNFFSVPEGVNPSSPGYNAGVFALTRKLPCPGRYAEITDWLYAQMARWADYLFLPDQAVINVAVDHFGWQATVLPRDYNRPASSSHADLKRAYIVHSTGPRKFWCYYYFREWYRGYAEWIKKGGAPVSVRKDSRAYVAFCRKFGLQNRVFFQLMPDCFARPVKALRFALKAWLKPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE09</accession>
    <name>A0A1Y4DE09_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57353">
        <property type="protein sequence ID" value="OUO57353"/>
        <property type="gene ID" value="B5F75_00845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="20083" checksum="318857BFB6399DBA" modified="2017-08-30" version="1">MAKIYQKSFSDGKNAGFTLIELLVVVLIIGILAAIAVPQYQRVVDKSRLTQVMTWAAPLIQAEKLYYMANGKYSPYMEELDTQVADCEFKSISYEAQGGRGRYTCNGDWTVDLNAWQKRIHIYLPDGGPVGSTVEFQFYLDQKKTLCGLRPVAGEMYVPVLAGPVRAEPALYSIGKFPIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA9</accession>
    <name>A0A1Y4DEA9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57483">
        <property type="protein sequence ID" value="OUO57483"/>
        <property type="gene ID" value="B5F75_01550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="358" mass="41074" checksum="2D62D4C5D515A48D" modified="2017-08-30" version="1">MIDRIKGGIEPKNVKELWPGAIEALKAQRIKNPHNKPVVSYHSKKQQVVFDVAAPRCLFGNNLAEATDSDLDELVTAIQCECTRNGVDVPKEAIYNAQIYYLEYGKNIILPITTSMTALFKRFGKGLTKGYNALEFHHYRKDRRDGYKVGISLDNRDIAFYDKTTKEIVGKSLYNKENKEIYCKLLAQGKQVLRYEVTFYNSPSVKANLSKFKQCSGTFTLRNVWDSKLARELLVSFSNEVLNNLPPAGCSKETELRQIKEARRAGVSISNVLIYKGLENLEKKLGANTVKELFNPIEERYAGGKKQYMQYSAAKNKQEKLAAYFKPRRDQTIRKIKRTINDFKPIRVDMRTKEIIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DED3</accession>
    <name>A0A1Y4DED3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57513">
        <property type="protein sequence ID" value="OUO57513"/>
        <property type="gene ID" value="B5F75_01705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027631">
        <property type="entry name" value="FeFe_hydrog_B1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="SSF53920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04105">
        <property type="entry name" value="FeFe_hydrog_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="141"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="488" mass="52971" checksum="8F5CA2096F0147BC" modified="2017-08-30" version="1">MNTSDNKAVYFKREALKKVVEAFDKGTLEKNAYRIPFEVIPPDSKSAVRCCIYKERAVFRARTLAAMGCSVEKDDEATSLNDYAKQALLRKAVPEVPLTVMDIACKGCVKARHIVTDACQGCLARPCQQACKFGAISFSDGRSHIDPDKCKNCGQCKAVCPYNAITYVPVPCEQSCPVNAIHKGENGFAQIDFDKCISCGHCMDACPFGAIMERSQLIDILGQIQSHNKVCAMIAPSIVGQFDCTLPQLMTAIKKAGFDKVTEVAEGADITTANEARELVERLEKGARFMTTSCCAAWIQAVKKHLPALKEFVSETKTPAGYTAEIEKKNGFVTVFVGPCVSKRVEGMEDPNIDFVMTYEELGAMLDAKGIDPSKCEETPLDPKISGEARYYGVTGGVAQAVENAIAGKRPFKKMAINGLDKKTMMLLNAYAKGAGDFQLLEVMSCKGGCIGGPCTLRKQAAVIKPIKDLVAQSPKVPCALDEKKETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH1</accession>
    <name>A0A1Y4DEH1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_05675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56109">
        <property type="protein sequence ID" value="OUO56109"/>
        <property type="gene ID" value="B5F75_05675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="7">
        <location>
            <begin position="124"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="891" mass="102683" checksum="845FDE1A557A8C33" modified="2017-08-30" version="1">MKLSFSLPYQTRLGESLHVLLYRAHASANERKINIPLATQDGKQWTGEIQLLLKQPAELAYYYEVRRGAQTVRSEWQAVPRHLYLEPSVSQYFLHDFWRDLPYASWLYTSAATEVFFPRAKNPSRPLALFARTLVLRAVTAQPGKGKLFLCGASKAAGNWNPAHALELTEGEPNEWTIALNADQLEYPFEYKFIVKEGERVLWEQGPNRRLYEPKLKNGQVWAENDLRPLFGQEQFFRAAGTVLPVFSLRSEGSCGIGDFGDLKLLADWAHATGQRVLQLLPVNDTTATRTWQDSYPYSAISVYALHPLYADMRQLPPLDKKTAKEFEKKRKTLNTLSQVDYEAVLQLKTAWLQAAFKQEGKKVLASRPFAAFYEANKHWLRAYAMFCVLRDQYHSADFHAWPRFSRYSPAELDAFCAPRSASYSDVCFWYYVQYLLHTQLLQASRYARQKGIILKGDIPIGISPHSVEAWTEPALFHLNAQAGAPPDDFSATGQNWGLPTYNWDVMAQDGYRWWKHRLTHMAQYFDAYRIDHVLGFFRIWEIPMHSVQGLLGQFSPSLPLSPEEIERFGLAFTPDLLRPYISEQVLFEKLGDLAQDAKKKYFSRTPDGLYEPLPAYNTQRKIEAALAGKTDEKTLRLKDGLFALVSNVLFVPDHRNPSQYHPRIGALTDSAFRALNAHDKEAFTRLYNEYFYRRHNQFWKEQALQKLPSITQATRMLACAEDLGMVPDCVPGVLQELQMLSLEIQRMPKRLGQTFADTRTYPYLSVATPSTHDMSVLRGWWKETPALTQRFWNEVLGRPGQAPQEADAQTCRQILQMHLQSPSMLALFSFQDWTAMDDALRAPNPEEERINVPANPRHYWRYRMPLTLERLLQEHTFAQLIRTLLNESGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH2</accession>
    <name>A0A1Y4DEH2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57456">
        <property type="protein sequence ID" value="OUO57456"/>
        <property type="gene ID" value="B5F75_01400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012395834" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="150"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="26089" checksum="D0C3D071A38D7829" modified="2017-08-30" version="1">MKKMMILALLAAPLLLSAQEAAQPAAAAQDAKPSVQDIAERNKMLYSLGFLLGDNLKRQLILDNEDDYKALSQGMRDSLLNKKSQTDLDQYKPAIIQKYQDDAQIISAKREAAQQEYLENFKKEKGVKELDNGTLIKLSRAGKGKTPKADATVKVHYTGTLIDGTKFDSSRDRDEAFETKLTDVIPCWTKALQQMKPGSRAKVVCPADTAYGNRPVGQIPPNSVLVFDIEMLSQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEH6</accession>
    <name>A0A1Y4DEH6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57554">
        <property type="protein sequence ID" value="OUO57554"/>
        <property type="gene ID" value="B5F75_01915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="N6_Mtase" evidence="6">
        <location>
            <begin position="381"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="890"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="5">
        <location>
            <begin position="1069"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1173"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1213" mass="140727" checksum="4881C50EFE98A389" modified="2017-08-30" version="1">MQKYKELLRVLGFQPKENAVDVYAKTYPNHRYVIEVDFQKEQINYGPLIKSESKTTQNFSQAENWVVLECVDRLLTKGYAPDRLILEKTWPAGHGTSGRLDVCVLREKDDSEYLLIECKTYGKEFDKAVAKMNKDGDQLFTYFKFSNKADVIMLYTSELQGKKVVYKNEIVKIEDDYRAGDVKDFYEKWNKLTKDNGIFESWVSPYCFANKALIKSQLKPINQEDSSFIFNRFLEILRHNVVSDKGNAFNKIFTLFLCKVYDETSKEDDEELEFQWKEGVDDHVSFQLRLTDLYKNGMKVFLSRTVSDFDESEFDNKYKHLSQETKAELLKEINTLRLEKNNEFAIKEVYDHDSFVENAKIVKEVVELLQGYKIRYNKRQQYLSDFFELLLTTGLKQEAGQFFTPVPVAQFIIKSLPLEDMIDKTLSSKTGDLLPYMIDYAAGSGHFITEYMHEVQDIINKKIPNKYIERTKKQLNYWQNANYEWATDYVYGIEKDYRLVKVGKVGCYLHGDGLANVILSDGLGNFANTKDYKGKLHKEQNDKQQDNQQFDILLSNPPYSVAAFRQTTRDYYTEKDFDLYQYLTDNSSEIECLFVERMKQLLKDGGLAGIILPSSILTNTGIYTKTRELLLKYFEFVAITELGSNTFMATGTNTVVLFLRRRNNYEYVNLQKSVDKFFNTHTDGSINGIEHPVSQYVSRVWEGLTFDDYLTLLDKNPNEKVQKHDLYREYTQKLTTKKEQEFWSKVLALEKEKLFYFVLAYPQKLVIVRTGEKEAEKQFLGYEFSHARGREGIHAIQRGKTIEECTRLFDLHSFDNPQKASTYIYKAFQKDLNVPIDDTLKENVSRLDLLDMMTFDRADFEKIINTKIKKKHIPSKYTQIKVGNLLLPLSKKYTIVAKKDIQEVGKYPVITQDEDFISGYCDLAHPVDELPIIIFGDHTCRVKYMEHPFMRGGDGTKLLKINERISLPKYVYYVLQHLIIPQGYQRHYTILKDSKIPLPPLEIQQKIVDEIEKIEQYAHAMLQDMTRLQQEINAKVSDIVAPLLPLDSVCKDIFAGGDLPEGNWSKICTDEYTVPIYSNGIAEKSLYGYTNIKKVEEDALSISARGTIGFTAIRKAPFYPIVRLIIAIPNKTIISLKYLWLVSKSLTMPQAGKTIPQLTVPMVKKIKLPVPSLQEQQKVVAEIEKLEQQIEKAQSAITQSEQQKQAILDKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI3</accession>
    <name>A0A1Y4DEI3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56119">
        <property type="protein sequence ID" value="OUO56119"/>
        <property type="gene ID" value="B5F75_05725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="157" mass="17345" checksum="E918863C2887BFCA" modified="2017-08-30" version="1">MSTNEQSKISLGSLITPARVLLAEDYPSKKELISALVQVVCRDYKQLDPADVAAQVLKREEGISTTLDTGLSIPHARLEELTDFAAAVAVLRKPLRETSGNELPIRVMFLFLSPAKPAFFQKHLQILSALAEKFKPEFIEELASLSNAEEVALRLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI6</accession>
    <name>A0A1Y4DEI6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosomal subunit interface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57564">
        <property type="protein sequence ID" value="OUO57564"/>
        <property type="gene ID" value="B5F75_01975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="2">
        <location>
            <begin position="129"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="183" mass="20538" checksum="971ECA939A2A99CA" modified="2017-08-30" version="1">MDIKITAKNIKLTPAIKEFINTRVGKVENFFDNIVSAQVLISVEKKINQRAEIILHTGAKTTISASAVESNLYKAIDAAAVKAEAQAKKIKNKAKARKVSKKSVKEADINPFAEHVLLPQTDVKFSVIKQVEVSPMNPEDAAYEMERLGYSFWMFLDEDSKQINLIFKRLDGTYGLIKPIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ2</accession>
    <name>A0A1Y4DEJ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">B5F75_05775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56129">
        <property type="protein sequence ID" value="OUO56129"/>
        <property type="gene ID" value="B5F75_05775"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="142"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="362"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="423" mass="45888" checksum="DBC15078BA21DD31" modified="2017-08-30" version="1">MARIKKITAREILDSRGYPTVAADVLLDDGNTGTAAVPSGASTGSHEALELRDGGERYNGKGVLNAVKNVERISQQLAGMDPFDIRLVDESMIALDGTENKSHLGANAMLAVSMAVLRAGCHSAKLPLYQHIRNVYGLHEDTYVLPAPMLNIVNGGKHADSGLDVQEFMIVPTAPKTFAEALREASETYHALRNLLKSEGMVIAVGDEGGFAPKISKHEDVLKTILAAAKKAGHPEISLAMDCAASEFYHEGAYRFEGKMYSAEQMTDLYAAWCKAYPLISIEDPLQEDDWEGWKLITQKLGKKINLVGDDLFVTNLKRLEKGIAQKAANSILIKVNQIGTVSETIDVMELAKKNGYSRIVSHRSGETEDTFIADLAVATNAGAIKTGAPARAERTAKYNRLLQIEAELGEKAVYAQNAAFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK1</accession>
    <name>A0A1Y4DEK1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56139">
        <property type="protein sequence ID" value="OUO56139"/>
        <property type="gene ID" value="B5F75_05830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="85" mass="9648" checksum="A673AE9617F8E0BF" modified="2017-08-30" version="1">MDFYQWCVLAAVVAFIVFVVFAVRAFLQITRTAEAVEYLAVSTAENVDKTKSAFDLIDNVSTLLDSTFYKVMKLGMDVIKHYRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK4</accession>
    <name>A0A1Y4DEK4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57496">
        <property type="protein sequence ID" value="OUO57496"/>
        <property type="gene ID" value="B5F75_01615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="310" mass="35033" checksum="8D5481DAD4223E0B" modified="2017-08-30" version="1">MKTALLVPVYNEQEVLPLFRQKVQEVAAQLPQEKFEYIFVNDGSLDGTAELLKEWARQDPAVKVISFSRNFGKEAALTAGLSQAAEADAVIILDADLQDPPELIIPFLQKYKEGFDVVYGQRCDRSQDSFLKRFTAGCFYKCYNAISTRPLPANAGDCRLLSRRAVRAVLALPERERFMKGLFNWVGFPTAAVPFKRQARPAGQTKWNYWRLWNFALEGLTASSTVPLRLWTYFGFAVSGFAFLYALWVAFQKIVYGNPVSGYASLMVAILFFSGVQLISLGVIGEYLGRIFIEVKQRPLYIIDEKINCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN6</accession>
    <name>A0A1Y4DEN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH</name>
        <name evidence="8" type="ORF">B5F75_01820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57536">
        <property type="protein sequence ID" value="OUO57536"/>
        <property type="gene ID" value="B5F75_01820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="195"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="605"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="619"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="203"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="429"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="643" mass="70491" checksum="96CF92428C52AE7A" modified="2017-08-30" version="1">MKNNKNQNNRRIVSVGQIVGWIAVFILAVLLFNKPGVKQTELDYSEFKHKVASSEVSDLTIAPGVISGMYKNEKGEFAPFKTVRMDDPELVSQLSAADIKYKAEADNSWVSNILFNVLWIFLLIGLWWFIFLRPQRNDGRSAMNFARSKAKMQDPSQQTVTFKDVAGCDEAKEELQDVIKFLKNPKKFQKLGGKLPKGVLLYGAPGTGKTLLAKAVAGEAGVAFFSASASEFVEMFVGVGAARVRDLFDQAKKNSPAIIFIDELDAVGRRRFAGIGGGHDEREQTLNQLLIELDGFESKQGIILMASTNRPDVLDPALIRPGRFDRHISVPAPDLKGREEILKVHAKKVKLGADVDLKVVAKGTPGFVGADLANVVNEAAILAARADKDAVTKSDMDEAVERVIAGPQKKSRIISPKEQRIIAAHEVGHTVVARLTNHSDPVHKVTIIPRGQALGYTMQLPLEDKFLTSKSELLDKLCILLAGRAAEEIVFGEITSGASDDLNKTMAYARKMVMELGMSDKLGPIALPTGDDGEVFLGRDLSRHHTYSPELARAIDEEIMNLIKSSYARAKDIITKNRAAFDKLVETLLEKEVVEAAEIDEILGLKPAASQDAQPQPAEPEPVKEEPKAPKAEKPEAQQAELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER3</accession>
    <name>A0A1Y4DER3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaK</name>
        <name evidence="9" type="ORF">B5F75_02235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57614">
        <property type="protein sequence ID" value="OUO57614"/>
        <property type="gene ID" value="B5F75_02235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="581"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="626" mass="66872" checksum="DA0B99508CDE5E7B" modified="2017-08-30" version="1">MAKIIGIDLGTSNTAAAVMEGGRGTIIPSAEGSSIGGKAFPSYVAFTKDGQRLVGEPARRQAIANPEGTVTAFKRKMGENYKYNLRGQEFTPQQLSAFILQKVKKDAEAFLGEPVEKAVITVPAYFNDNQRQATKDAGRIAGLEVVRLVNEPTAAALAFGIDKAGKEQKVMVFDLGGGTLDVTIMEMGKEGTFDVLATSGDTQLGGTDMDNAIIQWMVDEFRKQTGIDLSKDKQAQQRLKDAAEKAKIELSTTMETDINLPFISAGADGPKHLELQLSRAKLESLVDDIVKRCGKSVNQALSDAGLTASQIDRIILVGGPTRMPIVQKYVEDLVGKKIERGIDPMECVAIGAAVQAGILTGDVKDVLLLDVTPLSLGLETLGGVCTRLIERNTTIPVRKTQIFSTASDNQPAVTINVLQGERPMAKDNVPLGKFDLDGIPPAPRGVPQIEVTFDIDANGILNVSAKDLGTNKEQHITISSPNKLSDAEVEKFVKDAEKFAEEDKKHKEVIEAKNQGDSVLYQTEKSLKEYGDKVSQDDRLAIDRALSDLRDALKGEDVARIKSATDEALKAGQKLGEAMYKNAQAQQQAQAGAQAGAQPGPDASAQAGAAGNGGKDDVVEAEVVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET4</accession>
    <name>A0A1Y4DET4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57634">
        <property type="protein sequence ID" value="OUO57634"/>
        <property type="gene ID" value="B5F75_02335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012373161" evidence="2">
        <location>
            <begin position="24"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="398" mass="45760" checksum="2D32E379D590EB9A" modified="2017-08-30" version="1">MKKLLHWAAAGLLMLAAALPASSELTLPPDVMQYATEGINGVYSLDFDTAQKNIERVFKDYPDHPFAHFGNAMIAWSRYEYEYELSDDRQRKVFEQILDESIAGIKRWIKQYPEDPNAYMGIGALYGLRAMFTMRNRSWITAYFSGRRAIKNLEKSLELDPTYYDAYFGLGIYQYYAGTLPSVIKILAKIVAIKGDPDEGVAQLNLAREKAHFTSDSAKLILIEIQNTRNSKYYAPQKSLEYIRQLRAKYPKNPLMHYVEIICLYETAHYDEVTEQAEDFLKLIGTDPFYKDIYISRAYTALGTVQMQKGNFEQARALFEQGQQAIKNQEPSRWGVWNEVRLGEVYDVLGAREKAKKQYRYVLSFDDKWGFDDLAKKLLQTPYAVPASRDVGPLPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU8</accession>
    <name>A0A1Y4DEU8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="3">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_01290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57435">
        <property type="protein sequence ID" value="OUO57435"/>
        <property type="gene ID" value="B5F75_01290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="33"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="194"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="308"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="440"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="515" mass="56282" checksum="DD49D9CEDA1880C6" modified="2017-08-30" version="1">MVSELAGTLTKQKIDVDSLRKQFFEPNGTPVPVKFGTSGHRGSLGTGFCALHARAIAQAVARLHKEQNITGPILVGGDTRLMSADTARLCAEVLCGNGLTVILPDMPLPTPVFSFEIINGRASASLNGTASHNPPQDMGLKYNPSNGGPADASLTALIEKYANEYMKNPAEIKSVPLEEARQKGLLRTVDLITPYITALARVIDFKAIAASPLKFAVHPLGGSSLAFYEAIKEKYGLKNVEIVSKVQDPTFYFIPIDHDGKIRMDPSSKYPMSPLIKLVQDGTYDFAGASDPDADRFGCATKKGGLIPPNHALCVMADYLYRHHKVRDAYSIGRTLGTTALLDRIAEEHGLKLDEVNVGFKYFVEGIVKRKYVLAGEESAGMSVSGWTPEKDGILAVCLLMEIMATEGDIADLYDRLTAQHGTPYYTRVDVPTDEETKKRVKALKAADFENLHQVAGERVTRVRDTDGIKVYLQSSWFLVRPSGTENILKIYAETFISPKHLDALIEQAKKLLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEZ0</accession>
    <name>A0A1Y4DEZ0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57485">
        <property type="protein sequence ID" value="OUO57485"/>
        <property type="gene ID" value="B5F75_01560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="240"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="458" mass="51173" checksum="E4AB98C574DF3C2A" modified="2017-08-30" version="1">MFVPWFPKRYLLNSDISISRLVFAGPNWQIYKLGDGRNLLVVVTDLAQKWANLGLLGISVWRSVSFGGKNYQFIVSSDKYVLRPTNHDVAIADKTEALAFANSLRETRKLVPDIPLDNSIYVEQYARLLPLAETIDNSDDGLLLGTCLTGGVPVSIKAIRRLQNLTPYLSREDLHEIAQVAGVGIAKTLQRDPTDTESHKNHLLDCFSLPGATYLEQFFYENVIDIAFHPEKYEPLGISFPSPIVLYGAPGTGKTFAVEQLATFLDWPVFSVDSSSVGSPYIHQTSKKISEVFEKACSAAPSILVIDEMEAYLSNRDGAQEYKIEEIGEFLRLIPEASNHKVLVIGITNLLEKIDPAILRTGRFDHKIEVKMPDAKDIENMFRSAFEKLPVDQNIQAGEIISALIGKSRSDVAFVIKEAARLTAFKGKKQITQQELNEALHSGHFLYENNKRTIGFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF58</accession>
    <name>A0A1Y4DF58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HPr kinase/phosphorylase</fullName>
            <shortName evidence="10">HPrK/P</shortName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
            <ecNumber evidence="10">2.7.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">HPr(Ser) kinase/phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hprK</name>
        <name evidence="13" type="ORF">B5F75_01980</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46600"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>[HPr protein]-O-phospho-L-serine + H(+) + phosphate = [HPr protein]-L-serine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:46604"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The Walker A ATP-binding motif also binds Pi and PPi.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the HPrK/P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EC" id="2.7.4.-" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57565">
        <property type="protein sequence ID" value="OUO57565"/>
        <property type="gene ID" value="B5F75_01980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01918">
        <property type="entry name" value="HprK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01249">
        <property type="entry name" value="HPr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003755">
        <property type="entry name" value="HPr(Ser)_kin/Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011104">
        <property type="entry name" value="Hpr_kin/Pase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011126">
        <property type="entry name" value="Hpr_kin/Pase_Hpr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF1">
        <property type="entry name" value="PTHR30305:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07475">
        <property type="entry name" value="Hpr_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02603">
        <property type="entry name" value="Hpr_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00679">
        <property type="entry name" value="hpr-ser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hpr_kinase_N" evidence="11">
        <location>
            <begin position="14"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Hpr_kinase_C" evidence="12">
        <location>
            <begin position="143"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of both phosphorylation and dephosphorylation" evidence="10">
        <location>
            <begin position="214"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of dephosphorylation" evidence="10">
        <location>
            <begin position="276"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity" evidence="10">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="323" mass="35254" checksum="371FDF420312F792" modified="2017-08-30" version="1">MSRTGEVLEFTKSITVAELLQVKRLNLELVCGKRYIHREITLGSVNRPGLALCGHLDSFRANSVQVFGRGEHAFCVKENKSRLRANVEKMLVEGKVPCVIMAAGLDPLPAIRKACLSSDVPVLKTDMESSAFVAEFTRFLDEKLSPVTHMHGVLVDVSGTGVLIRGDAGIGKSECALELIKRGHILVADDVVEVQKRFGRFLVGSCPTMLKHYMEVRGLGILDVPLLFGVGSTLDETNIDMEVVLTSPNKQPIDRLGVEQKTTNILGIEIPSLGLPVTPGRNLAVLIEVASLNQQLKSQGIFSAKEFSQKILDKMKKGTNGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF74</accession>
    <name>A0A1Y4DF74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="14">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">secA</name>
        <name evidence="20" type="ORF">B5F75_02080</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="14"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57585">
        <property type="protein sequence ID" value="OUO57585"/>
        <property type="gene ID" value="B5F75_02080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004027">
        <property type="entry name" value="SEC_C_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02810">
        <property type="entry name" value="SEC-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 14 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="12 14 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 14 15" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="19">
        <location>
            <begin position="3"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="89"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="436"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="820"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="105"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OUO57585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="864" mass="98452" checksum="A4ED7BBF54EA9B74" modified="2017-08-30" version="1">MLKTIIDKIFGTKSERDLKKIQHYVDDANKFTAAFEKLTDEQLKAKTQEFKDRLAKGETLDQLLPEAFAVVRLAAQRVIGLRPYDVQLLGGIVLHQGKIAEMGTGEGKTLVAVLPSYLNALTGKGVHVVTVNDYLARRDRQWMGPIHEFLGLSVGYINHDMDSTERREMYAKDITYVTNNELGFDYLRDNMVINRADRVLRPLNYCIVDEVDSILIDEARTPLIISGPSEQSTDKYYIVNRLIPSLKVRMITEKDEVKAKYEGIKLDEGVDAIIDEKAHTATLTDTGIAKAEKFLNVPNLYNDVESEWVHHINQALRAHHLYERDVDYVVKDGEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEGLPIKEENQTLATITFQNFFKLYKKLSGMTGTAMTEANEFWQIYKLDVVEIRPNKPSKRIDYPDLVYLTEREKFNAIVDEVESLWKQGAPVLVGTRSIEKSEKLSHMLRAKGIPHKVLNAKYHEMEAQIISQAGRKGAVTIATNMAGRGTDIVLGGNPADPEEQKQVVALGGLHVIGSERHESRRIDNQLRGRCARQGDPGCSRFYISLDDELMRLFANTTKIASVLSTMGMKEGEAIESRLMTRQIEGAQRMVEGRNFDIRKQLLDYDKVMNQQRTAIYGLRNAILDGENMTEKSMQMMEEIVDELVEQYYQPAHLQRSDFEALNINLRNFFPGDFHFTAENVGRKSHDQLVDEIMAQVKDLYHARVLYFTEQGINFSEIERMLLLQIIDNAWKQNLYELDQLQNSVSLRGYAQKDPLIEYQKESYKLYSSMLNRVRDLMVSYIFRLQLPPRRTAAERAQQAAAKNPNKNAAPVSKHIGRNDPCPCGSGKKYKKCCGANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF93</accession>
    <name>A0A1Y4DF93_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="5" type="ORF">B5F75_02190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57605">
        <property type="protein sequence ID" value="OUO57605"/>
        <property type="gene ID" value="B5F75_02190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006488">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="4"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="82" mass="9283" checksum="84FF2C956D48CC15" modified="2017-08-30" version="1">MASKINFEKQLARLEEIVAQLEEEQTDLDASVKLFEEGVALSKELSQKLETVKFKVEELKKKGSELLTEPFDTELAEDPNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFE4</accession>
    <name>A0A1Y4DFE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57655">
        <property type="protein sequence ID" value="OUO57655"/>
        <property type="gene ID" value="B5F75_02455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032820">
        <property type="entry name" value="ATPase_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09527">
        <property type="entry name" value="ATPase_gene1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="85" mass="9320" checksum="15CD44456AA60487" modified="2017-08-30" version="1">MALGPFTKQDHLEITTLGMEFAVSEILGAGAGYWLDQRWDTSPWMLLAGAGAGFALGMYQVIRGAGKMSRSKTNLKKVEKEDGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFI8</accession>
    <name>A0A1Y4DFI8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56449">
        <property type="protein sequence ID" value="OUO56449"/>
        <property type="gene ID" value="B5F75_04450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="133" mass="14613" checksum="A84375F661A70A5C" modified="2017-08-30" version="1">MKDCENLMLYASGELEAQNKAAFEQHLQTCAACRAELALLRRTEEALAAPAAPAAVVEKLFSKTTRRKSFFAGWKPALAGTALLGVGIFMLLAGLHPDKTAFDASEVIAYMSENLDDEYLSFSNDLDLFEQEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFJ8</accession>
    <name>A0A1Y4DFJ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56459">
        <property type="protein sequence ID" value="OUO56459"/>
        <property type="gene ID" value="B5F75_04505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012734560" evidence="8">
        <location>
            <begin position="22"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="414" mass="45389" checksum="8EB92BBE5F1E313B" modified="2017-08-30" version="1">MYKKLTAVLLLSVLLADFSHGAGFALYEYSGRATAMGGAVMANKAEPASLATNPALITELEGTQAQVGVTVVTADAKTTVGGDSRTLKHDVWYLPNFYITQKWSDQVSVGLGGFSRYGLGGEYADPVQTWLGSNLAYKVRLETFSFTPTIAVKANDEFSIAMGLEAMIIGFSQSSYFNADPRNPGNFEISGSGVSWGGNFSLVYKPQWAEKWALGAMYRSKVKQNLNGRIDAGDKTFPAINIHSADAEGAISLPDSLSAGISFRPTDAWTLEAGIVGTFWSAYDQILIQYKDSETSPVIRNKKKYNDVYRLNFGTEYMLTPNWAVRAGYVFDKSPINQNEMDTLVPVDDRHIASVGVGYQTEKWSVDFAYAHVFARDLSGHSEQLVNPLTGQPMSMKYTDGKSDMFALTFGYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFM1</accession>
    <name>A0A1Y4DFM1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="8">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_04660</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56489">
        <property type="protein sequence ID" value="OUO56489"/>
        <property type="gene ID" value="B5F75_04660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006113">
        <property type="entry name" value="PTP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12968" checksum="FFCF8BD9D3E3EB2F" modified="2017-08-30" version="1">MLIKLIRTFSSAHRLPHYDGPCHQLHGHTWKAVFVIEGAVREDGMVCDFKVIKKLLDDNLPDHQFLNDWVENPTAENLAQYLFAKIGAELKKQNLTLKTLEIWESDNAAAVVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFP0</accession>
    <name>A0A1Y4DFP0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56509">
        <property type="protein sequence ID" value="OUO56509"/>
        <property type="gene ID" value="B5F75_04760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="185" mass="20658" checksum="6568B35DA5ED93CE" modified="2017-08-30" version="1">MRMDKIYQKSFFGGKNAGFTLIELLVVVLIIGILAAVAVPQYEKAVKKARFSNLQTMAETILHAQEVYKMANGIYSFDFNALDVTLPADMKPYLTTADGRVYAMQKSGMRCMFASTANLNPSGASFVACTSTKEPQLIYYITLASKNRYCGAKTGNTEAEEWCKYLTQKQTPSSRWGENSLYLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFZ7</accession>
    <name>A0A1Y4DFZ7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_05140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56579">
        <property type="protein sequence ID" value="OUO56579"/>
        <property type="gene ID" value="B5F75_05140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="3"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="454" mass="51112" checksum="3FD6D9ACD31219B4" modified="2017-08-30" version="1">MEEILKQQRAFFESGATLPVKNRLNFLKKLRHAIQTHRDDICQALYQDLGKSETEAYMCEIGMALEEIAYFLKHLPSLAKDRTVRTPLSNFHAKSIIKFVPRGNVLILSPWNYPFLLSMEPLVDALAAGNTAVLKPSAYSPHTSALIQKIIQETFPPHYVETVTGGRQENQTLLTQKFDYIFFTGSTAVGKEVLRRAAENLTPVTLELGGKSPCLVDETADIALAARRIVFGKFLNCGQTCVAPDYILCPENLQQPLLAALQREITRQFGPQPLANPHYGKIINEKHFQRLSALLTCGKIAAGGKTSPATLQIEPTVLTDVSWEDSAMQEEIFGPILPIITYSSLQEALKKIESRPHPLALYLFSTDKKRISQITQQIRYGGGCINDTIMHLSTPYLPFGGIGESGMGCYHGKFGFETFSHKKSILCKRNWIDVPLRYQPYSRWKQWLLKHFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG19</accession>
    <name>A0A1Y4DG19_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ORF">B5F75_02115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57592">
        <property type="protein sequence ID" value="OUO57592"/>
        <property type="gene ID" value="B5F75_02115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="124"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="160" mass="17733" checksum="4E32803D8295B543" modified="2017-08-30" version="1">MLTPAVYAGSFDPVTNGHMDIIRRARDVFGAVIVLVMPNACKRPLFTAQERVELLRQALQGEENVRVEATEGLLTDYLKKNGLKVLVRGLRGEGDLEHELVNAFYNKQFYASAETVFLPGRPEYAFLSSSAVREAFSYGADVSALVPPGVAEALQRKKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGN4</accession>
    <name>A0A1Y4DGN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56829">
        <property type="protein sequence ID" value="OUO56829"/>
        <property type="gene ID" value="B5F75_03005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="227" mass="25680" checksum="276379A39BA6486E" modified="2017-08-30" version="1">MPFDIYPWMNELIRQLQPVFKRRLQAVGLQGSFRRGEQTPSSDIDAVVVLDTLTAQDISLYKEILSHMPTTLTHPVCGFFGGKEDLKNWPRADLFQFMQDTHWLYGGLADVLPPPACEDARQAVQTAAGNIYHALVHTWVHGQLSADFLKLLGKSAFFMLQAAHYMRTGRYITTKWQLLQALSQPDEREILRFSLTPPPQEALPAAAARLLNVCQRLLAYCQRPSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGQ3</accession>
    <name>A0A1Y4DGQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56108">
        <property type="protein sequence ID" value="OUO56108"/>
        <property type="gene ID" value="B5F75_05670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="442" mass="48577" checksum="52FE00BA888AD441" modified="2017-08-30" version="1">MNTERPHKTFTQIMYMCLGFFGIQFGWALQMGNMSAIYSRLGAREDQIPLLWLAAPVTGLLVQPLVGYFSDRTWCRLGRRRPYFLGGAIFSVIALILMPQASAVWMAVIALWILDTSVNVSMEPFRAFVGDILPEDQRKTGYAMQSVMIGAGAVIASFLPQILTSLGVSTQAPLGHIPDTVKYSFYIGAVVLLAAILATIKTTPEYPPADMEAFKKLQKQTVSFKKTLSEMWQAMISMPSTMRRLALVQFFTWAAFMVMWVYFTPGIASGVFHAVPGTPEYETAANWGSSCFGIYNGVAFVFAFALLWLTTKFSAKKIHIACLTIGGIGLGSLGLTLFGLEFSKMGLVFPMVCIGIAWSSILSMPYAMLSNALPAEKMGFYMGVFNFFIVIPQICVNLFFGPFMKHLLNGSAIAAVGVGGISLFIAAAFTFWVQDRKTAVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGS9</accession>
    <name>A0A1Y4DGS9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56879">
        <property type="protein sequence ID" value="OUO56879"/>
        <property type="gene ID" value="B5F75_03275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="110"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="144"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="239"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="310"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="440"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="584" mass="63942" checksum="0E473597AE57B41E" modified="2017-08-30" version="1">MLPHKKDSAKVSVPSSERKLPEALSVLTKKPLVTLAIVAALPVILMLAFTFKSGYTPNSKNTKFDDIVIVKTPTEIADEATDALQKKDTQTFTDILNTQTKNNPNIVNSKGDPLIVMAATMGNLEAVQQLILNGADVNKANAFNKDTALLRSLYGNFPEITRLLVYSGADINAKNNYNHSPMYLALEKKLPEFIDLFLTSGVKEGLNSDNLFRASAKKNPMGVLAMLKGGVDPNVKNEKGNTPLIISASLGDVESVQALMAYRADVNAANNDGNTSLIYAARYNHPEIIRELLKPQTMQAPLDVNMQNKQGQTALYWGAAKGYEEVVRRLLAADADPTIAAKDGLIPYMIARKNKRGQVLEWFNKDIREVKNSVIEQDNAALIAQAKAEGRELPELAGQKNQTKPVTEDDIFTAAQTGDMELAKKVIASNKAAVFKKNKAGYTPLFIAVQNGQIEMVTYLVDNMARLFESSPQGNVFHVAVNTQNLEMLKHLVSLARKEGRLAMMLEYRAAPQKNAQSMTPLGYAALLCNKEIYDYLVSVGAKDGGLSKKPNILGYKTPADLMQECKAKPAQAKTLTRSAAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGY5</accession>
    <name>A0A1Y4DGY5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GGGtGRT protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56939">
        <property type="protein sequence ID" value="OUO56939"/>
        <property type="gene ID" value="B5F75_03590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025964">
        <property type="entry name" value="GGGtGRT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14057">
        <property type="entry name" value="GGGtGRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="331" mass="34846" checksum="45E25C0F8D0DE0D4" modified="2017-08-30" version="1">MITFEGYERRIDKINSVLKENGIASLEEAKEICTKKGIDVEKIVRGIQPIAFDNAVWAYTVGAAIAIKSGVKTAAEAAEKIGVGLQSFCIPGSVADQRAVGLGHGNLGAMLLSENTKCFCFLAGHESFAAAEGAIGIARTANKVRKTPLRVILNGLGKDAAYIISRINGFTSVETEYNYKTGELKIVSERAFSDGDRAKVKCYGADDVNEGVAIMRHEGVDVSITGNSTNPTRFQHPVAGTYKKWATENGKKYFSVASGGGTGRTLHPDNMAAGPASYGMTDTMGRMHSDAQFAGSSSVPAHVEMMGLIGMGNNPMVGATVAVAVAVAEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHA0</accession>
    <name>A0A1Y4DHA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57059">
        <property type="protein sequence ID" value="OUO57059"/>
        <property type="gene ID" value="B5F75_04215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012508812" evidence="1">
        <location>
            <begin position="20"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="316" mass="35192" checksum="FC6205D100CD776E" modified="2017-08-30" version="1">MKKLLTLLLVCAVAGLAFAAPAKKAAKKAKAPEKTKAEFIIVESDEYDAGKEDVLLTAGIAQFLNAEPTVTKVSYKEAAADPKMANLDYSFLPLYLIKKTDDIRAKLEKHLQYGYAQENDDFIILPRQTRQGVFNGKTGKPGVMELFVMSQCPYGAMAENLVIQAQKDGKMPEGKDIKVRYIVNYDEKNGFGSLHGPAEWEEDVRQLLIAKYYPEKFWKYLEIRNKDYRSSRWDKAMEEAGINTKKIMKKFDKEGIELLKEEAKYAAEYGVNASPTFLWEGKVQLDFGSAAQIEGFGFLNPNAAQPGAAAVPAGSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHU7</accession>
    <name>A0A1Y4DHU7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57239">
        <property type="protein sequence ID" value="OUO57239"/>
        <property type="gene ID" value="B5F75_00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="403" mass="43513" checksum="A2902772E9657837" modified="2017-08-30" version="1">MSISLSKLSAAIGDSPTLKINAKARALKAAGQPVIHLGGGEPTYPAPQAAVEAIIRKAQSRKIKYTPSSGTPEMKAAVLRYTQAHYGRTYEPANVIISAGAKQALFNFLLAAVDPGDEVIFPAPYWVSYPEMVRLAGGKPVVVRGEGRSLQVSAQAILQAVTPKTKAILLNSPCNPSGQIYGEDFIRQIVQFAEQNNIFLVMDDIYHQLVFDGKKTPNPCAFAKEGKNLVIINGVSKLYGLTGLRIGWAVSAHAPLIAAMGRMQAQSTSCNCDLSETAAAAALNGDQQVVADLCRILQENRDVLLKEAAQIPHIRVEKPAGTFYSFIDFSHYNADSSALAQYLLDKVLVAVVPGVSFGAEGYLRISFCADQTSIVEGMRRIRWALDKNAPKEIKIGDKLLTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI09</accession>
    <name>A0A1Y4DI09_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="10" type="ORF">B5F75_00530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57299">
        <property type="protein sequence ID" value="OUO57299"/>
        <property type="gene ID" value="B5F75_00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045498">
        <property type="entry name" value="HflX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19275">
        <property type="entry name" value="HflX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="9">
        <location>
            <begin position="192"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="151"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="198"/>
            <end position="205"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="224"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="246"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="312"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="414" mass="46006" checksum="39A721240B5793B4" modified="2017-08-30" version="1">MERVILVSVCLKSETFNEESLEELRRLAHTAGAEVAETFRVRVQAFGAAALIGRGKAEEIAQAVRLNEAQTVIFDDEISPAQQNNLEEIIPAKVIDRTRLILDIFAQRARTQEGKLQVELAQLKYLLPRLGGKGTALMQQKGGIGLRGPGETKLEYDKRRLRLRISKLEKEIEQVKQERSLRRQRRGQIPLPQIAIVGYTNAGKSTLLNALTNQTAVYADDKLFATLDPTTRRVRMPAGGEMLFTDTVGFIQKLPHSLVSSFRATLEETTFADVILHVQDASSPHRAEQAATVRKILTDLGAQKTPLIEVFNKADLLSPARQALLQAQVPQALFVSAARGTHLRQLLEQVEEAAAYRWKLHRLVLPPQSFALLGKIYEKALVTGRKEKPSGAVELTLMATDGNFASLQKLLKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI87</accession>
    <name>A0A1Y4DI87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56658">
        <property type="protein sequence ID" value="OUO56658"/>
        <property type="gene ID" value="B5F75_05560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038713">
        <property type="entry name" value="Terminase_Gp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005335">
        <property type="entry name" value="Terminase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03592">
        <property type="entry name" value="Terminase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="135" mass="15044" checksum="FED88F4B2716A7CA" modified="2017-08-30" version="1">MAAKKTKAARLTKKQVKFCKEYLHTGNATESARRAGYSAKSAYSIGAENLKKPEIQDALSKEGARNAAKFNYTLEQHVEELDHLKALALAAGEFSSAVKCEISKGRVMGFYIERKEVALDMEPRNFVFEIVQAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIM3</accession>
    <name>A0A1Y4DIM3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57519">
        <property type="protein sequence ID" value="OUO57519"/>
        <property type="gene ID" value="B5F75_01735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00786">
        <property type="entry name" value="5_NUCLEOTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011831185" evidence="1">
        <location>
            <begin position="19"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="23"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="301"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="487" mass="53582" checksum="E8F430DE164A7A42" modified="2017-08-30" version="1">MRKTWLLTVFLFVPLLLAAKTTTIYHTSDVHGFFYPKNGQGGFAALAAVLKEGPQGYLLLDSGDFSNGTVETRNSKGLKGVQMMNRMSYDAATIGNHEFDFKGEGLAPLLANAQFAVLAANFFETATGKYPPSVLPYKIFDENGIKIAVIGLANREPTNPSKLYSYGKPLAALEKALKEVEEKEPNIVVVLVHDSLQDEKHGTQSYVGEIGRKFGGRVHVVLGGHAHNILQNKYIGGTLFVESGCNLQNVSRVSVETDDKTGKFVSAKSELIPLVIAQTGEDPDMKAYADSLREPGVDEVVGESPALFSRLPQRDDQQDAALNDWIADIILDYSGAQIAVHNNGGTRVDMQKGPVTKRDLIDIHPFDNTITLVNVDGRFLKKFIKKSFAPNSLYSYAGLTISYKQNKKGKIKDLEIFVNGQPVQNRKKYTLATNSYIAGGGSEGWMFKKIPAEYKKLAGDKTIRDLMEDALRNGPVKVPETGRIYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIQ9</accession>
    <name>A0A1Y4DIQ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_02950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56818">
        <property type="protein sequence ID" value="OUO56818"/>
        <property type="gene ID" value="B5F75_02950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="134" mass="14962" checksum="16549B31A8EE3263" modified="2017-08-30" version="1">MSTHKNRTVMAEINMVPFIDITLILLIIFMVMSPMLVQMQMTVDLPKSQAINTQAEDDVIRIEVQKDGTISVMNKKLTLKNLERELILRMGKASKKTILVQADKDVPIQQVVDVFDIAKKLGAAKLGIGVLSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIT1</accession>
    <name>A0A1Y4DIT1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Outer membrane protein assembly factor BamA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56230">
        <property type="protein sequence ID" value="OUO56230"/>
        <property type="gene ID" value="B5F75_06325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071709">
        <property type="term" value="P:membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013096531" evidence="5">
        <location>
            <begin position="22"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="119"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="283"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="362"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="787" mass="89665" checksum="B6F668D13999939C" modified="2017-08-30" version="1">MPKRFLLLFLSGLLAFSYARAEETVSQEVDPNGPWMICDVAVSGLKNIRKKTVTKASHSKKGELYDRFTISEDIHDISALGNFDQVEIDISRMPGTRTEKDGQEAYPCHRITYLVQEKPIFDRLTYEGRKHLGKGAITQAMTLKLKDPFNEAKLETDLERIKAKYAEKGYINANVTYELTRDEKLGVVYVKLIINEGERVRVSAVNFNGEAPELPVEKIIKKASNRPGKVFKPQNLQKDWVKMTLYGRNKGYSEFTLSAPQVEMNEAKTEAAITYDLTEGEKVNFGSVSFEGNNVFTQEELDKQVFFREGKLYNQKDFDDTIVSIQEQYANKGYLQVRVNPVKKIENGRLDITFDISEGHIFYIDNIDVTGYEKTKKYVFTRELSIHPGDLYDNEKIRRSQTKILNLGFVNDVQIDLQPTADPQKVDLGFNIVEGRPGMFTAGLAMSSMDGLYGEVSINHMNLFGRAQRLSLRTLFGKEILDYTVSWSTPWIYDKPTSLGIDLFNTRRYRSFYTENQAYTEKRLGGRIKVGPRFNDDIYQLSFGYSFENIDIYDIDAQFLPPNANPGDPNYLQKGDTNMSTFSVDFAIDTRDNIWDPTRGWRNSLGLALAGGPIGGDLDLWYLNARSIFNHTVWNVGGNYPIVFVLSNKIGSVQAYGRTEEVPPYEKFFLGGADTIRGYERAGEVGPLYGGDMYYVMNAELRFPLAREGRRNMAQLAFFFDLGNSWNKFDDLEFSLGPDVNQFKAGVGVGLRFTTPSLPIRIDWGYGLNHKSNEDRSHFYFNISNMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ44</accession>
    <name>A0A1Y4DJ44_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56968">
        <property type="protein sequence ID" value="OUO56968"/>
        <property type="gene ID" value="B5F75_03735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012531332" evidence="1">
        <location>
            <begin position="23"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="338" mass="37216" checksum="85A7F2A5C02A502F" modified="2017-08-30" version="1">MKNLKWMLAVLTAVLITAPVFAQAPKSSARTAQEGLSASIERAAVKAVRQHQKKVCCYCGEEILYPGQHCSASGYVSLCTTQEYQPAKRTDSTPSVCPKCGEEYTIDEKYHGAKHVCQVKDAQEEQAPVCCRCGEEILSKGQHCAASGYVSLCTTQEYQPAKRTDSVPSVCPKCGKAYTIDEKHHGAKHVCQAENTQEEQAPVCCRCREEILSQGQHCQATSCTSLCTTQEYQPAKRTDSVPSVCPKCGKAYTIDEKYHGAKHVCKTAQKDTVEYCIYCGEPIVENNQKCTVAKGMDCRVRCPECTVNLRDPKNLNAAGTHYCRFKLVIKPVKPHTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJB3</accession>
    <name>A0A1Y4DJB3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57038">
        <property type="protein sequence ID" value="OUO57038"/>
        <property type="gene ID" value="B5F75_04110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013096544" evidence="1">
        <location>
            <begin position="24"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="449" mass="50009" checksum="D534624A14BF5266" modified="2017-08-30" version="1">MVNAEMRKIILFLVFCLALPAAAQKNMLPAAKAVVGKTALQTAVKTPALPALATGAAFALPAGQGAPVSRHFTLKDLFSAQTGASDASAGLLKSFSARGYERELKENDLQQLQKFINTYAEIERLKTTYSSFDYAQLFSTSFFHMTVFSPLAIQNNQIVLHTLNHYIQKMKWLQQNTNLAKEAFVKGADPQHQPQGAEGGSNVFAQLARQLSQEKLIMLGEYHFVPAFQRAVVNLVLTLKKQNPNRRVVLFTEFIPLPKEKSGNGQTLATYYKHFTAPEIQPLAATDQRLFLYAPSLFRQLIKHQVEVYPLEDTRQFALLAKETSGSLDAPVITTARNKSWVRVMAAKMAEIRQTDPDALFIVYAGQAHTSWLSPMALPKFFAAEKPVVVELALNRLLDHTSLKILWPSDDPLFINPPLHPSFFSWQGEDSRQLANCSGFDYLLVVPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK14</accession>
    <name>A0A1Y4DK14_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA_pol_B_exo2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56670">
        <property type="protein sequence ID" value="OUO56670"/>
        <property type="gene ID" value="B5F75_05620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019288">
        <property type="entry name" value="3'-5'_exonuclease_PolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10108">
        <property type="entry name" value="DNA_pol_B_exo2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol_B_exo2" evidence="1">
        <location>
            <begin position="118"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="259" mass="28903" checksum="21F8EA3828CFEC99" modified="2017-08-30" version="1">MVMCKQPVNLLAEAQAVNTGLKHFCFDIETGNAASADINTKAQEAKMPAKAKTAQEQQAAKIEAYQKAVEKAALLDRAPIMVLCAATDAGNVVWSCIPSKCPVKTMPGLAAEIRNFKTEKEMLLDLRDWLAERTSELTEIVGFNSRGFDLPKMRNAYIRHKLQLPALFVPGVNPHYDVMREYLRNYTTEFNGQLFVKLKTVQNRLGLPEYKEVISGADAPKLAAEGQDKLVIPYCYMDTMTTYLAYKLMTGQIEDVKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK20</accession>
    <name>A0A1Y4DK20_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucosamine-6-phosphate deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57268">
        <property type="protein sequence ID" value="OUO57268"/>
        <property type="gene ID" value="B5F75_00365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004342">
        <property type="term" value="F:glucosamine-6-phosphate deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01399">
        <property type="entry name" value="GlcN6P_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004547">
        <property type="entry name" value="Glucosamine6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018321">
        <property type="entry name" value="Glucosamine6P_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11280">
        <property type="entry name" value="PTHR11280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00502">
        <property type="entry name" value="nagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01161">
        <property type="entry name" value="GLC_GALNAC_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="1">
        <location>
            <begin position="14"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="275" mass="30176" checksum="309E3FCFDA49DB51" modified="2017-08-30" version="1">MRLVVTKMNLGLWAAAYVKEKIHAFRPTAEKPFVMGLPTGGTVVDFYANLRLFYKEHLLDFRHIVTFNMDEYVGLPQDHPQSYHSYMRQNLFSEVNIPPENTHILDGQAANLPLECAQYERAIRQAGGIHLFLGGVGRNGHIAFNEPGSSFDSRTRPVNLTAATIQANSRFFLNDVHRVPTQALTVGIGTILQAQELLFLASGPSKAGAVAQLCKPGLSEACPLTALKLHPHATLLADSAACALAEGPIRQQLDALMHSQPDAPHWVVELPKEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK89</accession>
    <name>A0A1Y4DK89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57338">
        <property type="protein sequence ID" value="OUO57338"/>
        <property type="gene ID" value="B5F75_00760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="12"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="180" mass="19956" checksum="F83CDEA8FC0FCB58" modified="2017-08-30" version="1">MKKVKIEKALTFIEPGPLLLLTTFDGQKNNVMPLSWAMPLDFDGRFALCTGPWNYSFGALRKQKECVLCVPGPALLKTAVKLGMESGEDTDKFKKFSLRTLPASQVKAPLLADCAACVECRVERFWQAYGIFVLKALQAWENPSCADGRMVHAVGDGTFRADGEKFNLRRLMKAKLPPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKH8</accession>
    <name>A0A1Y4DKH8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA_SAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56800">
        <property type="protein sequence ID" value="OUO56800"/>
        <property type="gene ID" value="B5F75_02850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_SAD" evidence="2">
        <location>
            <begin position="105"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="17397" checksum="5DA7612EB2C6CF8F" modified="2017-08-30" version="1">MTTNPELSPKKDYYAPMHTAEHILNQTMVRVFGCARSKTNHIEKDKSKCDYFLPVAPTEEQMREVEALVNDVVASQLPVTAEELPRDVAEKSVDLSSLPEQVSTVRLVRVGGYDVCPCIGKHVQNTREIGRFKLFSWDYQNGRLRVRFKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKS2</accession>
    <name>A0A1Y4DKS2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycerate kinase type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57528">
        <property type="protein sequence ID" value="OUO57528"/>
        <property type="gene ID" value="B5F75_01780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031388">
        <property type="term" value="P:organic acid phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018193">
        <property type="entry name" value="Glyc_kinase_flavodox-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004381">
        <property type="entry name" value="Glycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018197">
        <property type="entry name" value="Glycerate_kinase_RE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036129">
        <property type="entry name" value="Glycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21599">
        <property type="entry name" value="PTHR21599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02595">
        <property type="entry name" value="Gly_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006078">
        <property type="entry name" value="GlxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110738">
        <property type="entry name" value="SSF110738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00045">
        <property type="entry name" value="TIGR00045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR006078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="377" mass="40497" checksum="51E2A59AC3DB7900" modified="2017-08-30" version="1">MHILVLPNAFKGSLSALQTARLLTRYLSPLHAVKAYPISDGGDGFIDFFRALYPASRVIYLQAKNAFLKNKRTSFLMLPDRKTAVIETARICGLGSAKKEELDPMGASSFGVGQVILKAVRQGATQIYVGLGGVACNDGGAGMAVACGAHISDKNGNEIPLGAAPLLRAAKLELKQLKQNLKGVRLYAVADVTNPLLGPHSSAKVFGPQKGASPAQVKVLDRAMAQWARVVKRATRRDIAHTPSTAAAGALAAGLYGCFGAKLILGSEFLFRKAHLESAFDWADWVITSEGKLDAQTFYGKAPLAVLKLAKKHKKPVLFICGLLEEKALARQKYRPNQIAVLADFAPTPDACRQYPAVYLKRLCKHLFAGESACGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKW4</accession>
    <name>A0A1Y4DKW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56940">
        <property type="protein sequence ID" value="OUO56940"/>
        <property type="gene ID" value="B5F75_03595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="233" mass="25210" checksum="B7FF6F6B99533960" modified="2017-08-30" version="1">MSCEKCTPEVMNMCCVCKGAKHDPAPIPEEGKWVKAKQITDISGLTHGVGWCAPQQGACKLTLNVKNGVIKEALVETLGCSGMTHSAAMAAEILPGKTILEALNSDLVCDAINTAMRELFLQIVYGRTQSAFSDDGLPIGAGMEDLGKGHRSQIGTMYGTEAKGARYLEMAEGYVLEIGLDKNNEIIGYKFVNLGKMMDAIKKGEDPKAAFEKNVSKYGRFDEAVKKIDPRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL07</accession>
    <name>A0A1Y4DL07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56980">
        <property type="protein sequence ID" value="OUO56980"/>
        <property type="gene ID" value="B5F75_03795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011004302" evidence="2">
        <location>
            <begin position="23"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="26261" checksum="741EAC6AD68F9153" modified="2017-08-30" version="1">MNRKVIYLFTLCLFGTCGILQAQPAVEQNAGVSPAEASRLTGKTAPGVKETLAAQADVSVETVTAPAAQEPVAPAAQPGEVLPVAANAPEGESFVAPREEVTEVVETPAAPKVVYNPKNHRDPTLSPDDFLLLQYREQQRLAALEAERQRKLAEERRRREEAERLRQLELARIKDPTREVRNKIRVTGIIGEEVFIGDKIYTIGKSIYGARIVEVRPEEVVFSYKGHKFVRKVQLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL17</accession>
    <name>A0A1Y4DL17_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_03845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56990">
        <property type="protein sequence ID" value="OUO56990"/>
        <property type="gene ID" value="B5F75_03845"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SATase_N" evidence="8">
        <location>
            <begin position="74"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="279" mass="30599" checksum="451B9E73B620D366" modified="2017-08-30" version="1">MRPAVSDLFSKTAEELKQTFDKKFFQRAKFIPSAKKTIAIFCALKDFIYQYPLESGRETLPVGLESLACRLEEQIKNSLCFLCQEKADCARCEQNARQITQDFILALPQIQRLVISDVNAAYEGDPAAISPVEPLLCYPGVTAVTLQRMAHFLHARGVRLIPRIVTEYAHSLTGIDIHPGASIGPAFFIDHGTGVVIGETCVIGANVKLYQGVTLGAKSFPLDPNGNPVKGIKRHPNIEDDVIIYAETTVLGNITIGRGSVIGANKWITQDVPPHTKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL43</accession>
    <name>A0A1Y4DL43_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56141">
        <property type="protein sequence ID" value="OUO56141"/>
        <property type="gene ID" value="B5F75_05840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="70" mass="8093" checksum="F5E97C0317968562" modified="2017-08-30" version="1">MTAQEKKIVENKISELKKEMNEVHGSKCEVYSRVVGYLRPVQNWNKGKKEEFAMRKTMHIGCGCDCNSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLJ1</accession>
    <name>A0A1Y4DLJ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56271">
        <property type="protein sequence ID" value="OUO56271"/>
        <property type="gene ID" value="B5F75_06550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="3">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="441" mass="48868" checksum="1B312F2D9B12218E" modified="2017-08-30" version="1">MKKTFILDTNVLLHDVNCLHAFEDNDIIIPMAVIEELDAFKSEGDTRGKNARMVSRTLDEMRKQGRLNEGVKLPKGGILKIELDKPNALPQSLAFNKADNSILNIAYTLSKKEGSYKKNAAPVIVVTKDINMRLKAEALGLSAQDYTSDKVNVDELYTGVAEMEVSPEQIDAFYRDKKLPVDPNVYFPNEFIILKSSDGSKKSAIGRVSNGAEFVLRPLSSQEPVAWGIKPLNKEQRFAMELLLDDSLDIVTLVGTAGTGKTLITLATGLQRTMDENAYRRLVVCRSIVPVGKDIGFLPGTKEEKLEAWMGAIYDNLAFLADRKNPDEGEEKAHYLLDSGKIEIASVTHMRGRSLPGQYMIVDDAQNLTPHEMKTILTRAGEGTKVVVTGDPYQIDTPYLDVESNGLTYLVDRLKGQKSHGHITFTKTERSHLADLASKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLM0</accession>
    <name>A0A1Y4DLM0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57200">
        <property type="protein sequence ID" value="OUO57200"/>
        <property type="gene ID" value="B5F75_00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012034188" evidence="1">
        <location>
            <begin position="27"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="465" mass="50499" checksum="B41A9DE74DCAE705" modified="2017-08-30" version="1" fragment="single">MKNMKHFILALLGKAAVCAALATVSAAPLFAQTAEVRSAGVYYKNNALGTDQVYCNWGNSVVSGNNDVSFTTKVSPSSNANKNDPWVSSALIEYDQPYPSPNVNNNYPNHCLALCMDVYCTNKPMAQSTYSIAFPLQQVKFDIVKYYNGKNVENPEETPAVRTIDLYPDTESDSAICGSYHCPGGPTEGLTCPSPKYELVNGTCYNFGTTQSVSISNCQLGSKDNNGNYANCPNDTCPYVIFNNDGTRSNQPITFCAAWDGSYEIAGEFGKSNGDFAFRSTVSTDFPGDNIITDKIEFSSTIAYPGMNQIPMQVDVTNVHTVRSTPTVVGNITAVSAQPYTFAYRLSKDADVRVAIFDASNGDDIAYGQTSNNNNLAPTQLVRTLVDWQPRIGEGMKGVDKDTQITEFDSWDGRDDNGLLLPAGNYIVAIQAKAQDEWPGVDFSRAVTRQMSLDPLKLTDIVATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLX5</accession>
    <name>A0A1Y4DLX5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57300">
        <property type="protein sequence ID" value="OUO57300"/>
        <property type="gene ID" value="B5F75_00535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012101958" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="48"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="329" mass="36208" checksum="7741CB05EFB2D69F" modified="2017-08-30" version="1">MRLLCIFLFSLCFTPMLQALEQAPAPINENAFLIQKEIATWPTDQTFNTQVSVYNCQAVRLHPNWFLTSAHCVYSACATRPCTVEITLAESPDLLARVRVKHSTVSPSVYIYPGFFPGQNRISGMDAALIRFDPQKAEYSYINLEDGRALTRGEFEKKLRFDTEAQAQLNAAGARLLNVSGIGTSKLKPQIVVPKTTAGVISYLPGNSPEVYFVQELQHFISPGFGVRQGNSGGGVFTRSGDLVGLVSSLLYAQDGSASFHDAEGKTLLTLRNARDFFFFTGFNGSTLNFIRNKVPNLRTVGVIPDFATPSNKKFDAIVKAEQAASLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM03</accession>
    <name>A0A1Y4DM03_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56431">
        <property type="protein sequence ID" value="OUO56431"/>
        <property type="gene ID" value="B5F75_04345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="280"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="652" mass="72914" checksum="5EA388F3C347048F" modified="2017-08-30" version="1">MMAAKKQDFRVKLSVCSVVAFLLLFMAARLALLLLNRDFFSALGGGEIFSAFLNGARFDLSIIALFVGPVVFLLNWPVKSPRWVKIWASVLVVQWIFLAGFLIGDLIYFPKVNRHIAEEIIQLSNDWGFIISYIFTQTWLPLVLLLGLLAFAVWGISRLTDKYYAPRQWGIAKNAGFLLLLIALCVLGIRGHLGGGKSLGVADVYNYTDSPAGSALILNGAFTAYQVGRKGTLDVVNPYPVEQAVKTTQKLFISPDEELPDPAYPLMRRHTDEQDHQHYNILIVLLEGWHPYYVDGLSGNHFGATPVFDQILTDGVTFTNAYAVGQRSIFGFAAVFAGLPWVPGLPMFGYGLELAALSPMPKHFSNMGYYTFFAQTSRRSSYRLCALASYLGAQESYGWEDMPQLLAYQEKAPFGYDYDAMMFAADKIKNRKQKNFMGMLFTGITHEPFTSTLPQFDKYPYDTWEHGFLNTLSFADWSIGELLKRARQDGWFDDTIFVFVADHTSGGPADDSLKNHFRIPMVIYAPNILKPRQIDYIVSQTDLIPTIYRLTGLTPAYTAFGRDMLDETDADKRVALVSEGVNIGLVTPQGEIRHGGGKILSSQAYTPGFDEQQAEETLLALDKTAQTLLTENRWYNPAFDAAAVKETQQNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM29</accession>
    <name>A0A1Y4DM29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56451">
        <property type="protein sequence ID" value="OUO56451"/>
        <property type="gene ID" value="B5F75_04460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012734563" evidence="2">
        <location>
            <begin position="24"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="506"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="566"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="642"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="713"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="749"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="803"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="835"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="865"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="932" mass="98062" checksum="0549DE2AD5B54FAC" modified="2017-08-30" version="1">MKQVIASLVSISILTLGPLPAPAQVPQKAVQAVKAVAKSGVKKAIVPPVKYPHISVPAVSLSQTMLPAETGRFAVPRVSVELKPEQRQQLERGIAVTVKKALEPSSLTLAQIRARIAQGNTERLAQRILTYPNPSVREGMLRNEFVQVALAGHASLEQIEQAADLWRQDIQQAIDALPDLPAGDLPALAQAYAQKNKSVRAVSDALASTSALGLFGTQEDAALLADFSKQAAGSSLAPLVQTAAARALLRLGAVDALQQTTQTAADPALWQGLYTQAAKRGFSLPAPESSARPADTKAFTDVLGVYGKINLLAADPSAEATAVYMNLGRTRPTAARPLQNNQSVPLAPLPRLPRLNIATPEALQVAALAAPAETSAQAASSPTGFLARAARTDQAAKPPHAAQHSVRFFARTPQNAASDRAGILYGGFPLPAVAAGVKKAWSYLKKRFTPAPAALHPEPTSAQGGLAGVFQRASLYLASFVMGLEVATPVIANFGSSFGLSLSDNILVAVATYLPYSLGAFLSNWLKQKIGRKASMNLGLALMGGGFTAGVTLFGLNGAFVPQADALAHFYNILGCITLASTGGVFVHNAVGPMMTDLSAGASELALQKRNANTELSRALGMAASFAFPFLSTKVLGLDWSFTFALPIPLVAAAALGINLARIPNTKPVVEPKPQPLTAQAAAQGIKNRRAYTLTSSLLNNSYIRLLKEEKGVLALLTGLLTMNAVEMSFNNGFLFLLPGLTADPSSQYLFGLIQFAAPFLIGRYLARSFLKWFPQRNMSVATLVSALGGMAAWPLADNVYALTAALFAAEVGISTTFTLAFARSAKNIRTQDRIVSLIVASAVSCAFGPMLLTNLAEMFMSTGLFGAAGATAAAMIGVPSALALFSAGLFKRVERVQAAPENALSTEPQKTPQKRLSWLKKLLSRVSGKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM58</accession>
    <name>A0A1Y4DM58_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recA</name>
        <name evidence="12" type="ORF">B5F75_00995</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57380">
        <property type="protein sequence ID" value="OUO57380"/>
        <property type="gene ID" value="B5F75_00995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="10">
        <location>
            <begin position="35"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="11">
        <location>
            <begin position="199"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="353" mass="37908" checksum="C958BEDB9854618B" modified="2017-08-30" version="1">MDANKQKALDLALGQIEKAFGKEAICRLGGGSVKNVEAIPTGALSLDLALGVGGLPRGRVIEIYGPEAGGKTTLSLHVAAQTQKMGGTVAFIDAEHALDPVYAANLGVNVDELLVSQPDSGEQALEIAEKLVRSGAIDLIIVDSVAALVPKAEIEGEMGDAHVGLQARLMSQALRKLTSILNKTKTSIIFINQLRQKIGVMFGNPETTPGGLALKFYASVRIDVRRIENLKKGDEIIGTRVRAKVTKNKVAPPYRQAEFTMILGHGISREACIIDKGVEAGFIEKSGSWFIYGDEKLGQGAENARQYLKDNPELAAEIEDKLYVKYLGHHYNGKKADAAETKPAEDAKKPVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DME8</accession>
    <name>A0A1Y4DME8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">[FeFe] hydrogenase H-cluster maturation GTPase HydF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56571">
        <property type="protein sequence ID" value="OUO56571"/>
        <property type="gene ID" value="B5F75_05095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023873">
        <property type="entry name" value="FeFe-hyd_GTPase_HydF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041606">
        <property type="entry name" value="HydF_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040644">
        <property type="entry name" value="HydF_tetramer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18128">
        <property type="entry name" value="HydF_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18133">
        <property type="entry name" value="HydF_tetramer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03918">
        <property type="entry name" value="GTP_HydF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="9"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HydF_dimer" evidence="2">
        <location>
            <begin position="168"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="HydF_tetramer" evidence="3">
        <location>
            <begin position="268"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="392" mass="43362" checksum="5A4F2BE1C4D3FAF8" modified="2017-08-30" version="1">MVKLNRPHIGIFGKMNVGKSSLINALTGQQVSVVADHPGTTTDPVKKIIEILGVGPVTVLDTPGIDDTSALGTQRVERTNEALDQVDLAILVFADQFDSYDQTLMETCVARKVPFFFVHNKSDLQKLNVEIKGADVVDFSCKSPALLPRLLEMIKKHLPKSSYSQDVILDDFVKAGEEVVLVIPIDASAPEGRLILPQVQTIRNLLDIGAVAVCLKDTELRKYLQTHTPKLVVTDSQAFGYVKTVVPPTIALTSFSILFSRLKGDFDAFLRGTHAIDRLQDGDRVLILESCSHSVNKCDDIGRVKIPNLLRKYTGKKLEFDVVANLDPIPADAEKYKLAVQCGGCMVTRTQIMRRLEILKEKKVPLSNYGLTIAYCNGIFERVTEIFRKKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMX8</accession>
    <name>A0A1Y4DMX8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="10" type="ORF">B5F75_02530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57670">
        <property type="protein sequence ID" value="OUO57670"/>
        <property type="gene ID" value="B5F75_02530"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="5"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="122"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="415" mass="44896" checksum="8C8E80E9B9D7C9F2" modified="2017-08-30" version="1">MYPDLQKTDPAVFSAVAKELGRQREKLELIASENFTSLAVMQAQGSVLTNKYAEGYPGKRYYGGCEFVDEVEQLAIDRAKQLFGAEHANVQPHSGAQANMAVYFALLQPGDTVLGLNLSHGGHLTHGHPMNFSGKLYRIVAMNVRPDTEEIDYDEAANLALEHKPKLIMAGASNYSRVFDWKRLREIADSCGAYLACDVAHYAGLIAAGEYPNPFPYADVVTTTTHKTLRGPRGGLILCKEKLAKAINSAVFPGTQGGPLMHVIAGKAVCFGEALKPEFKAYQHQVKQNAAALAQALLVRGYRLVAGGTDSHVMCIDLRSKGLTGKAAEAALDKAGITANKNTIPFDPEKPFVTSGLRLGTPAVTTRGMKEADMAQVAAFIDDAISHAQDEAYLAQIAGQVKKFLEKFPLYPQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN55</accession>
    <name>A0A1Y4DN55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="11" type="ORF">B5F75_03065</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56841">
        <property type="protein sequence ID" value="OUO56841"/>
        <property type="gene ID" value="B5F75_03065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="140"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="367"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="656" mass="72598" checksum="B1FE31382EB9AED3" modified="2017-08-30" version="1">MYCKVVFDVPLDRDFDYAVPAELENKIMPGVRVTAPFGRVLTGGMVTSVSEICTAPKGVTLKEIASVVDKRPLFGSDLFPLMRFMKAQWGGPIGQILFSLVPPQPYFKLDNAPTSVHIDIKTPSMRLTPCQETALQTVRAFAAYEFHPVLLNGPSYTGKTETVLRLAGEVLAGYGQVLITVPDIAAARQFISEAEERFGADNVFCWHSRMLLSKKKKYFSAVSNGLPCVVIATRSGALLPFKNLRLAAVLDEGDDNYKQEENKPYYHLRELLMFRAKMHGAVLLFVSATPSLELLQKVHRQEVAQLSFTQAVPGHAFTPQIKLTDKKGEKSRFLSDFLLAQLTENLQRKETSLLILNRRGYSNAYYCLNCGAYAKCKKCGAILARENTPEHGDRLVCKKCGHTETLQQECPHCHNLIFKSRGGGTQKVVTELAKFFPKAHLLRLDSDTLKTKAGQGFEALNALKSGRADIIVGTRLASGALRGAKITLAAVLDAELELDGPDFRASEKYGQMLFALRGHLSGVSDGRLIIQAADKEAYDYEHLFAGDYNAAAQSELALRESFAYPPYVHLAKMLIKAKDADVLAAETARIKRLAAPLVCQTLGPVWCAKKTDVLKKQYLLFKTDEARWLELVAALDSFVPVKKASVKLSADPYDFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPX0</accession>
    <name>A0A1Y4DPX0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_01155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57411">
        <property type="protein sequence ID" value="OUO57411"/>
        <property type="gene ID" value="B5F75_01155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="19"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="174"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="279"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="427"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="483" mass="53617" checksum="8F4D128E7CBF02E5" modified="2017-08-30" version="1">MCTKEFTNIKTGECMAAEIKFGTDGWRGIIAWDFTFENVRRLAQALADYINENAPVGENGKQPKIFVGYDRRFMSDLFAADIASIFRSNKIDVTLSSCPISTPVAACLSLSKFWMSVMVTASHNPPHYNGIKIKLAGGSASSRVTKEIEEYLDQNSVLFLYGQKAEQKDCSDLYFKYVAAHANTKKLKTFKSKVVIDYMHGAAAGYLEKFLSPKQVIALRADREPTFEGEQPEPVEKNLSVLKKTVTEKKAALGIAFDGDGDRVALIDEKGTYLTPCMIAAVLCNYLVKYKKLKGKIVQTVSMGYLLKRIARKYEMLFEEVGVGFKNVAERMSLDDVAFGVEESGGFAWKGNLPDRDGLTVALAFLGIMAATGKKASQLCADVVQEYGASVYMRRDLPISKPVDKAALSEKLRKKLPKKINGRRIAETLTSDGLKIVFDNDEWLLLRPSGTEPLLRIYAESATKKDTQALLNFGEKILAPYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQC5</accession>
    <name>A0A1Y4DQC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphocarrier protein HPr</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57571">
        <property type="protein sequence ID" value="OUO57571"/>
        <property type="gene ID" value="B5F75_02010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="89" mass="9842" checksum="1A7B93E2E5D55DA4" modified="2017-08-30" version="1">MIQQDIQITNRLGLHARPAASIAQTAAKFACDIKLTKDHVTVNAKSIMGVMMLAAEFGSHVQLTTDGSDEKEAFEAIKKLFDDKFNEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9C8</accession>
    <name>A0A1Y4D9C8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000014">
        <property type="protein sequence ID" value="OUO55854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55854">
        <property type="protein sequence ID" value="OUO55854"/>
        <property type="gene ID" value="B5F75_07265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO55854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="19567" checksum="ABF5BBD484F5A1F3" modified="2017-08-30" version="1" fragment="single">NANPYTRDTVTVEENPNYVAGSAVAGEEQYVVTLKREQINIETDTTATWPPRLCDRTTDAAIFTAVGGGTCNAGSTCYVDPAKVTQTNACIYVNDTSFTNYPTTPAQAASEVVDVRLQPIKTFDRSATKVGEGMVITEEWDALYFYNPTPSSERHTQEEIAQCTGATDVKQCPYEMVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA40</accession>
    <name>A0A1Y4DA40_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">23S rRNA (Adenine(2503)-C(2))-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_05765</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56127">
        <property type="protein sequence ID" value="OUO56127"/>
        <property type="gene ID" value="B5F75_05765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="104"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="353" mass="39806" checksum="634251F01A279CE2" modified="2017-08-30" version="1">MIKYIQLFARIFGMNFESVKQYIKKAGLPNFRIAQVQEAIFKKGISSWDEATSLPAQLREELKKDFPLLSFEVTDITCSKHDKVAKALLTLKDGFRIETVLLKPQDSWSVCVSSQVGCALRCSFCSTGKMGFKRDLTEEEITDQVLMWYQYVRREKLGERISSVVFMGMGEPLLNYLNVVKAAKDLSKPDYLNIGARHISISTSGIADKLHKLAVDLPQANLAVSLHNADNAERSQLMPVNRRYDLDDLKKALEEYIAMTGRQVFLEYSVIENVNSRPEHIRKLADWIYSIKDNYLLHVNLIACNLGRGEKTDERVVKDFAAGLKAMGIGVTIRKSMGNDILAACGQLASQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAA7</accession>
    <name>A0A1Y4DAA7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56143">
        <property type="protein sequence ID" value="OUO56143"/>
        <property type="gene ID" value="B5F75_05850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186891" evidence="1">
        <location>
            <begin position="20"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="251" mass="28203" checksum="788B36AE8D87185E" modified="2017-08-30" version="1">MKRIVLLLLLTLISPAVFAQTTVNASAIERAAKAAHNQKADQVSKLTAQTLADLKAFQKAAFRYQYYDYNFMFQSMDALRESYMQLRGASETAAKSVAPQINEPIAIANGQRSIRLAAYLNMETCTLWQSEQPKFDAFAEALQADLQEGVALPAEFKQTLASFREYVKNSKQLNSNWVLQSMMPVMDVFNKYAKANSPLVPAMARQIQEPMPAGWGGEVVASTFIKDHSCELWQIGDQLENFRANLLKYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAC8</accession>
    <name>A0A1Y4DAC8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="9" type="ORF">B5F75_07030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56026">
        <property type="protein sequence ID" value="OUO56026"/>
        <property type="gene ID" value="B5F75_07030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="4"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="177" mass="20345" checksum="ED5DC1DC0A975C08" modified="2017-08-30" version="1">MSEEKAWYVVHTQTGHEDKVREKILLNIEIQNFGDRVFQVLVPTEEVVEVKQNKKILRKRKFFPGYVLVQMKMTSEAYWFIKSITGVTGFLGDPNPVPLPEEEIAGIVELTDNTSGKPKHVVEFERGESVRITEGPFKHFIGVVEDVNEQKNKLKVMVTVFDRATPVEVDFLQVEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAE0</accession>
    <name>A0A1Y4DAE0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56197">
        <property type="protein sequence ID" value="OUO56197"/>
        <property type="gene ID" value="B5F75_06155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011005647" description="PpiC domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="156"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="272" mass="31039" checksum="290C1C4FD319CC84" modified="2017-08-30" version="1">MKRCLLIAVLCLAVWGCKKAADTIPDDAAARVGRETITEEDIAARTALLSEDDRAFAKTPIGRQNLLQIITREKLIAAAAKDEQLDQSDVYLSIMEDKRAQLADIYRQFGEQTLEQLWYDELKEKGDTAVTDEEIDAYYDKYPYEMTIQQIIIDNAQTADQVLRALKASPRRWNELERQYSCAPDALRKLSFMPGEYLPDIEVIAANSPTNSVQGFFKTAQGFHIIKKTGEKRLSRKAAEPRIREVLENKKLDKILDALKNKYEVVIYEKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAF9</accession>
    <name>A0A1Y4DAF9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_06240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56214">
        <property type="protein sequence ID" value="OUO56214"/>
        <property type="gene ID" value="B5F75_06240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032585">
        <property type="entry name" value="DUF4912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16258">
        <property type="entry name" value="DUF4912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="308" mass="34417" checksum="EC6AF007207202E2" modified="2017-08-30" version="1">MGEKILLQTKRVRYYITMTQNLSSSALVKPLAKDVHAEADIPSGYGKTESFLLPKDPAWLFLFWEITPNTLDCIKSQYSEDVLKNARTVIRLHDVTNVQFFDGNNSVTHYDMPVIFEARSWYINAPQAGRTYLADLGYLTADGKFILVSRSNSTLLPPGKVSDIVDDKWMIVEGDFQKLLKLAGADYIGLGASELMHVLGQRWKLTELTSSGAPSSWSSFALHLDKVQPEENEDIWLQADCEIIIYGSASKNAIVSINGKEIELKEGKFSIRQHLPAGSVVDLPIKARNAKGDKTRQINIKALREQGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAH7</accession>
    <name>A0A1Y4DAH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">B5F75_06360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56237">
        <property type="protein sequence ID" value="OUO56237"/>
        <property type="gene ID" value="B5F75_06360"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="235"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="251" mass="26885" checksum="D49B42615EC29667" modified="2017-08-30" version="1">MTKRTPIIAGNWKMHNTLAESAALITALTKAGNKNHVEIIVAPSYTSLAKVAELAKGSEIQVAAQDVHWEDKGAFTSAVSPVQAKDAGATHTLIGHSERRSVFGDTDEILNKKVAAALRHGLTVIFCVGETLEEREAGKTLSVIESQLKNGLKDFTEEQLKGLIIAYEPVWAIGTGKTATPDQAQEVHAAIRAYLAKAYSPAFAEATRILYGGSVKDSNVDEIMAKEDVDGALVGGQSLIAEKFARIINFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAM5</accession>
    <name>A0A1Y4DAM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatB</name>
        <name evidence="12" type="ORF">B5F75_06440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56253">
        <property type="protein sequence ID" value="OUO56253"/>
        <property type="gene ID" value="B5F75_06440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="11">
        <location>
            <begin position="332"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="481" mass="53330" checksum="4498BEA392941799" modified="2017-08-30" version="1">MNTEFEPVIGLEIHVQLASKTKLFCSCPNGVGEDTKPNTAICPVCTGHPGVLPVLTEGALELAVRAGLSMNCKTNEYSSFSRKHYFYPDLPKGYQITQYDEPINGAGFIEITFGPKDHLQKKRIGIHHAHLEEDASKSSHEGTYSLIDFNRAGCPLLEIVSMPDLRSPDEAYAYLTEIKRLMRWVGASNCDMEKGELRVDVNISLRPKGQEKFGTRAEIKNLNSFKAVRDALNYEINRQTEILNAGGQVKQETRLWDKEELVTKPMRSKEDALDYRYFPEPDLPPVVLEKSWLEGVKSRMPELPAAKEARFMKAGLSAYDAGVLTSSREIADYFEEVTKSGKVSLKTASNWIQTDLLGMLNAEKKEIQDSPIPAARLAELLEMTESGKINRKQAREVFDEIWKTGEAPAAVVEKRGMVQVSDEGQLEEWAQAAIAANPKAVADFKAGNKAAVGPLVGAVMKMSKGKANPRLISQLLTKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAR6</accession>
    <name>A0A1Y4DAR6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (cytidine/uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could methylate the ribose at the nucleotide 34 wobble position in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56294">
        <property type="protein sequence ID" value="OUO56294"/>
        <property type="gene ID" value="B5F75_06675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="17422" checksum="939A5EE6B6C37AAE" modified="2017-08-30" version="1">MLNIVLVNPEIPFNTGNIGRSCVATGTRLHLVGKLGFKIASKEIRRSGLDYWPHLDYRRYDTWEAFLEAEKPTEDNMFFLSTKGKTAYWDASFPPDAFLIFGAESCGLPKDFYERYRHRLFTIPMPGPVRSLNLSSSAAIVLFEAIRQNHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAS0</accession>
    <name>A0A1Y4DAS0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56303">
        <property type="protein sequence ID" value="OUO56303"/>
        <property type="gene ID" value="B5F75_06725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013391285" evidence="1">
        <location>
            <begin position="21"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="227" mass="26713" checksum="5D7022A6A4F3C1F0" modified="2017-08-30" version="1">MRKVSFLFVAFILMFTAGFAGDKTTREATYKQLVAQRQELLAWETEHPMAPKLMAMYKTKEAREIRQQLYQNFPDLRRQEISQFRKELRQELQKSQTVPFVTFNTLPLENLKKLTANKKLLLEFLKAYPDNAVNLTDEYLLRLFQEDEALEEMMTSYLLYLKIYHANPAAARLSSEQQKMLQTTYQMGNMPRMYNLLFSYASAGLSKARRELARQYVRNSLVSAFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB45</accession>
    <name>A0A1Y4DB45_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_06525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56266">
        <property type="protein sequence ID" value="OUO56266"/>
        <property type="gene ID" value="B5F75_06525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="24"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="299"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="405" mass="44014" checksum="95031387872D4B51" modified="2017-08-30" version="1">MKFERFVAVRYLTRRQGLFAFITTLIGVAGVSVGVAALITTLSVMNGFQTDIKDKIIGAQSHILVFGRMSKDTYQKNIRLIEQLPLVEAAAPHIYGQGIITYAGQSVGLIVRGLDPEQEKKINTLADSVEEGSFTPDWPEDAPPPLVLGSELAANLGADIGDDVVLISPQSISTSAGMFPKMKKFRISGLLRTGYYEFDNTIAYTLLSHASDFLGLRQGTTGIAVKLHNINDADKAAAQIQDVIGHGYSVRTFAQLNSTLYAALKLEKTMMFIILFLIIGVASLNIAGNLILLGTEKLRDIGIMRAMGASPRMIRKIFMWEAMVIAGLGIVLGLLLACLLCWIIATFNIVELPGDIYYLTKVPVRMQLWDIVAVIGGSCLICFAAGLYPAVKASRVHPTDAIRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBA4</accession>
    <name>A0A1Y4DBA4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplV</name>
        <name evidence="10" type="ORF">B5F75_06950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56346">
        <property type="protein sequence ID" value="OUO56346"/>
        <property type="gene ID" value="B5F75_06950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="119" mass="13034" checksum="55E354147BC88C32" modified="2017-08-30" version="1">MEACAKAKFQRFGSRKVNLVLDQIRGKNVKAAEEVLPFVAKRTSDLVAKTLHSAAANLEVKAGKKLDFSKVFIKEAFANLGPSGHLKRVQPGPQGRAMPYKKSMCHLTVIVTDEKKGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBK6</accession>
    <name>A0A1Y4DBK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04895</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56533">
        <property type="protein sequence ID" value="OUO56533"/>
        <property type="gene ID" value="B5F75_04895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="325" mass="36517" checksum="DD90B60B328AAE28" modified="2017-08-30" version="1">MSVPVQITHLYKTYTRRRWIGKNWEKPVLKDISLTLEENHVLGLVGESGCGKSTLCKVLLGIEKPTSGQVLADGKDVAVLSKSEFKKLRRVMQVVYQDPYSSLDPRMTVRQILSEPLEIHGLKKEPRERDAFLKDLLAAVGLSDTQLERYPHEFSGGQRQRICIARALALDPKILVADEPVSALDVSVQAQILNLLKKIKTQRHLSMIFVTHDFAVARFLCDDIAVMYQGRIVEKAPAEELFLHPQHPYTRALLAAVPSVQRPRLHPEELAEAPGRTDWACPFAARCAYAQASCKSNRFELKEIFPRHACACGVLPFATEKKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBL0</accession>
    <name>A0A1Y4DBL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">B5F75_06400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56245">
        <property type="protein sequence ID" value="OUO56245"/>
        <property type="gene ID" value="B5F75_06400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="106"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="293" mass="33485" checksum="D75D8EBDD883DE40" modified="2017-08-30" version="1">MEKWVDAFLLHLQNKNFSPYTLKSYRADLQEFLLFFKQRRQDDLRYFTSANIRSFLAALQTQHHPARNTVLRKIASLRSFAAYLLEQGQLERNPFKLLPAPKREKILPKFLSVPETQRLLETAAHSKHFAARDKALFELMYSSGLRRSEVTGLCVKDVDFFNGIVKVFGKGAKERLVPVTDAALDAIRTYLASRPHPQPQDPLFLNKNGKRLTGDGLAYIFKHTAIASHLARKVTPHSLRHSFATHLLNNGCDLRSLQEMLGHKSLAATQVYTHVSLEKLKSVYDHAHPKSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBM7</accession>
    <name>A0A1Y4DBM7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56265">
        <property type="protein sequence ID" value="OUO56265"/>
        <property type="gene ID" value="B5F75_06520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="162" mass="17822" checksum="9BDF7477CD94BD7A" modified="2017-08-30" version="1">MEKGFTLIELLVVVLIIGILAAVAVPQYTKAVDKARFTQVLTMMDSLKKGIDTFYLANGAVNILEKDLLDAMDIEVTGINCTTNTCTSDLGGGWSVGWSIRGQQNLYLVYAIIYKPSDSSNTMFMLQELLMNGKWSRYCVPQSSAAGKTMCDQLTQNGWTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBN9</accession>
    <name>A0A1Y4DBN9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="2">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56557">
        <property type="protein sequence ID" value="OUO56557"/>
        <property type="gene ID" value="B5F75_05020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="3">
        <location>
            <begin position="34"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="22164" checksum="AF022D432255C163" modified="2017-08-30" version="1">MLLNLIKLIARIYFRVCYDFKVEGLENIPKTGALIIAGNHLSNADPPAIGSFAGLVRDSRFVAKKELFSVPVLGWFFRRSGYIPVDRKRTIGDFGALKEVVHYLEQGESVVMFPEGTRSRTGKPQKPKSGIGFLVYKTGAPVLPVKIEGTFGWPWVRRIRVKFGQVMHLEKDPALEPKAQYKQFANQIMDAINSINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBQ2</accession>
    <name>A0A1Y4DBQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56295">
        <property type="protein sequence ID" value="OUO56295"/>
        <property type="gene ID" value="B5F75_06680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="17138" checksum="54934359DB574B19" modified="2017-08-30" version="1">MKKGFTLIELLIVMVVVGILVTVALPKYYSSMERGRALEGISNLRAASDFVNAKYVMQGNQYVKNSIADTSDRLLGGDTTKRSYFGFPLLYSLSSDTAVIFTSRADGSYDLYAINQDGELKYIACSGDAELCKNAGMEEATFTDSYSNSNLILNFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR8</accession>
    <name>A0A1Y4DBR8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">B5F75_06735</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56305">
        <property type="protein sequence ID" value="OUO56305"/>
        <property type="gene ID" value="B5F75_06735"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="42"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="116"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="192" mass="20798" checksum="71881ECCFC8C86D5" modified="2017-08-30" version="1">MPRNNMDVLCLLQEHGAILEGHFVMPSGFHSQTYIQTSLLMQHPHLAQRIAGALSDKFTKKADVIMALTPSDSVLAQEVARARGVRAIFASRADNGEMLLKHNFTIKEGENVLIVDDVAVSGRKINKAIELVGKMGGNVIGVGVIVDRSMGYLPLAVPLRALLSYPMQTFTAKECPLCAAGLPFSKLEETGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBS9</accession>
    <name>A0A1Y4DBS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">B5F75_07060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56032">
        <property type="protein sequence ID" value="OUO56032"/>
        <property type="gene ID" value="B5F75_07060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="88"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="127" mass="13577" checksum="C82E8C05DEEA70E5" modified="2017-08-30" version="1">MAHTKAQGSSSNGRDSHGQRLGIKRYGSQFVNAGEIIVRQRGTKFLPGTNVSRSSDDSLFARVAGIVTFEWVKRGKKQISVYPKVAETKEEAKAPAKKAAAKTAKPAAKKPAAKKAPAKAKKAEADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBV3</accession>
    <name>A0A1Y4DBV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murA</name>
        <name evidence="9" type="ORF">B5F75_05380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56624">
        <property type="protein sequence ID" value="OUO56624"/>
        <property type="gene ID" value="B5F75_05380"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="2-(S-cysteinyl)pyruvic acid O-phosphothioketal" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="423" mass="46112" checksum="2DC5C6454EBC77A8" modified="2017-08-30" version="1">MDRFIIHGGKKLHGTVHISGSKNAALPILVATLLTDEPCVLHRVPNLRDVRTTLKILEYLGKKVEYKDNTATITADGTLKNTLPYELVKQMRASFWVAGPLLARFKTAEIPLPGGCAIGVRPVDIHLKGFEKLGAECETKAGNVILRARELTPAKIVLRFPSVGATQNLLMCACLIPGETVLENVAKEPEVDDVIAFLNKMGADIRQGEKGQLIVHGKTALHGAEHTVVADRIETGSYVLAACATRGDVTVSGCVPEHNSILWEDLQEAGFTLDIQKDAIHVLPYEGAIKPVRVRTAPYPGFATDLQAPWMTLMTLCDGTAEVDEDIFENRFMHAPELVRMGADIVTEKSVARVTGVKELSAAHVQASDLRGGMALVIAGLCAPGETEVERVYHIDRGYENLEQKLTALGADIRRYNPDKNEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC17</accession>
    <name>A0A1Y4DC17_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-galactopyranose mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_05235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56596">
        <property type="protein sequence ID" value="OUO56596"/>
        <property type="gene ID" value="B5F75_05235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008767">
        <property type="term" value="F:UDP-galactopyranose mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004379">
        <property type="entry name" value="UDP-GALP_mutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015899">
        <property type="entry name" value="UDP-GalPyranose_mutase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03275">
        <property type="entry name" value="GLF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00031">
        <property type="entry name" value="UDP-GALP_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GLF" evidence="4">
        <location>
            <begin position="153"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="374" mass="43903" checksum="8F1413FD5838676D" modified="2017-08-30" version="1">MKKYKNLVVGCGLSGAVMANKLANELGETVLVIDRKKHIAGTCYDYKNEYGITVHQYGPHIFRTNSKEIWDFLSQYTQWYPFMHKVLGLIDGIEVPIPFNLNSLYKVFPPQMAAGLEAKLIAAFGFNKKIPILQLRGTQDKDLHFLAEYIYTKVFLGYTLKQWDYTPEQLDPSVTGSVPVYISRDDRYFQEKYQAIPRQGYTKMFENMLHHPNIEVRLETDFADIQKEVSYERLIYTGAIEEFFNYKYGKLPYRSLDIKIETFDTEKFQNAPVVNYPENYDFTRIAEYKYFLNEKSPKTTLSFEYPENFEEGKNDRIYPILNEANQAVYDRYAADAKTMPNTYFIGRLGAYRYYDMNRTIANALETFKLIKNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC39</accession>
    <name>A0A1Y4DC39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase T</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56425">
        <property type="protein sequence ID" value="OUO56425"/>
        <property type="gene ID" value="B5F75_04315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="212"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="290"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="411" mass="45574" checksum="E2645F1313445AA6" modified="2017-08-30" version="1">MNQLQQKIYDRFVRYVAIDTTSDPLSTVTPTTASQMSFAHMLAQEMKTVGFTEVEVDEYGFVTGLLPANTDKKAPVIGLFAHMDTVCDYSGKDIRPQLHPNYDGGTLTINADKKMYLTPQTAPKLNLCIGDDIITADGNSLLAGDDKIGIATIMTLAEYLTQHPEIKHGPIKAAFTIDEETGTGIAYFNIEKFGADFAYTVDGSTLGDIDCGNFNADTVTLHIIGKTCHPGSAKGFMANPVRIAADIISSWPEDKLPETTEGEEGFVLFKDIEGGLDKVVVKGIVREHDLAKFENLKKMLEELVAEKRQKYPAAKIEVEFKKQYRNMREILKERPQAMELLEKALNENHVQYRLTQARGGTDGAQMSLRGLPTPNIFAGYENPHGPYEWISLGWVEKAFRVLESIVKDAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC59</accession>
    <name>A0A1Y4DC59_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GtrA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_04430</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56445">
        <property type="protein sequence ID" value="OUO56445"/>
        <property type="gene ID" value="B5F75_04430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="135" mass="15330" checksum="763AE8212277EE1E" modified="2017-08-30" version="1">MFSLLCRQLARLTRLPEQFIRFLIIGSLNTAFAYGLYSLFIFIGLHYSLAVLCSTIIGTLFSFKTFGNWVFFNPDNRLLLRFAIVYGGCYGLNVGILKTLTLAGVSNLYLAGLISSFLVAMVSFFLNKFFIFKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCC6</accession>
    <name>A0A1Y4DCC6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Galactose-1-phosphate uridylyltransferase</fullName>
            <shortName evidence="10">Gal-1-P uridylyltransferase</shortName>
            <ecNumber evidence="10">2.7.7.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">UDP-glucose--hexose-1-phosphate uridylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galT</name>
        <name evidence="13" type="ORF">B5F75_04850</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56525">
        <property type="protein sequence ID" value="OUO56525"/>
        <property type="gene ID" value="B5F75_04850"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00571">
        <property type="entry name" value="GalP_UDP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000766">
        <property type="entry name" value="GalP_uridyl_Trfase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023425">
        <property type="entry name" value="GalP_uridyl_Trfase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39191">
        <property type="entry name" value="PTHR39191"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006005">
        <property type="entry name" value="GalT_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01239">
        <property type="entry name" value="galT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01163">
        <property type="entry name" value="GAL_P_UDP_TRANSF_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="7 10 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="11">
        <location>
            <begin position="56"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="12">
        <location>
            <begin position="251"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="501" mass="57090" checksum="8384CCDA5074D677" modified="2017-08-30" version="1">MDINLLIDQLIAFAVNEKLLPARDRAWAVNQLLDILHLSDYTPSGFSGKTPPYPCEILKNICDWAAQQGFISPDTVTMRDLFDTKLMGVFARQPSAVTDEFFALYKKSPKAATDKFYHDARALDYIRTERVAKNLAWKARTPYGSLDITINMSKPEKDPKDIAAALTVKASSYPPCLLCKENEGYAGRVNHPARQNLRLVPLDLLKDGKPWYLQYSPYVYYNEHCIFLSDRHEPMKLTRKSFERLLNFVDFLPHYFIGSNADLPIVGGSILTHDHFQGGRYVFAMEKAPVEQTFKLKKFPRVKAGIVKWPMSVIRLNGSKKDLIEAGEYILKKWRTYSDPKADILAKTGDTPHNTVTPIARRRGKAFELDIVLRNNRTTEEFPMGIFHPHAEVHHIKKENIGLIEVMGLAVLPARLAKELKALEAPLIKKDLAAIWKDESLSKHAPWAEELLKKYAFTARNTAEILRTEVGKVFARVLEYAGVYKRTPEGKAAFERFIKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCD9</accession>
    <name>A0A1Y4DCD9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56535">
        <property type="protein sequence ID" value="OUO56535"/>
        <property type="gene ID" value="B5F75_04905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012711902" evidence="1">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="146" mass="16257" checksum="44D9064B83C0927C" modified="2017-08-30" version="1">MRHLACLLSLLLLCACGGYETVTVTLPDGFAVRARVADTPQKQEKGLMFVKKLPENEGMLFVFEQDEEQAFWMKNTLIDLDMVFIGSDKRVTSVAHQVPHSYTYTPDSQVAYALGYGQYVLELAAKTAQKHGVEAGAELHFELADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCE7</accession>
    <name>A0A1Y4DCE7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56545">
        <property type="protein sequence ID" value="OUO56545"/>
        <property type="gene ID" value="B5F75_04955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012983309" evidence="1">
        <location>
            <begin position="22"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="17638" checksum="22CA8B1427AB0C2D" modified="2017-08-30" version="1">MFFRRTALTIAALFVSGGLCAFDVQYGSFFAVHDVSVEDGRPVLPLARGKYANVRMLDEETFFFVKNCSGNCRQPAVSADARIVEMRAAQTRADMWIADVSFGGQWLITFLIFKNPTGYRVIEPEHFSFLNDSLQQRVRQMLFARAAQEAAPKEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCJ7</accession>
    <name>A0A1Y4DCJ7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">[FeFe] hydrogenase H-cluster radical SAM maturase HydE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_03025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56833">
        <property type="protein sequence ID" value="OUO56833"/>
        <property type="gene ID" value="B5F75_03025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044271">
        <property type="term" value="P:cellular nitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018130">
        <property type="term" value="P:heterocycle biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901362">
        <property type="term" value="P:organic cyclic compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042364">
        <property type="term" value="P:water-soluble vitamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024021">
        <property type="entry name" value="FeFe-hyd_HydE_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034422">
        <property type="entry name" value="HydE/PylB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43726">
        <property type="entry name" value="PTHR43726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00348">
        <property type="entry name" value="FeFe_hydrogenase_maturase_(Hyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03956">
        <property type="entry name" value="rSAM_HydE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="48"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="349" mass="39020" checksum="65336DF19C83D6AA" modified="2017-08-30" version="1">MQTLDDWTQKYLSRPPLTRGDILPLLSLSDPAPLFRKADSIRRRFVGDGVYLRALIEFSNYCKNDCMYCGIRRSNAQAVRYRMTPNEITHTARQAVAAGYKTVVLQSGEDLWFDADKMSDIIRRIKNLGAAVTLSLGEKTREEYAAYRKAGADRYLLRIETTDKNLYEKLDPAMSWDNRVRCLEDLKELGYEVGSGSLVGLPGQTLESLAEDLLFFKSLPVDMAGIGPFIPHPHTPLAQEKADGHFELSLKMMAIMRLMLPDINIPATTAMETLHPQGRLLALQCGANVIMPNVTAETFCKNYELYPGKPHPGARAAAAWQEQLASIGRSVSAGYGFHGDYLKEQRAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCJ9</accession>
    <name>A0A1Y4DCJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rod shape-determining protein MreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_06825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56322">
        <property type="protein sequence ID" value="OUO56322"/>
        <property type="gene ID" value="B5F75_06825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04093">
        <property type="entry name" value="MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="164" mass="18326" checksum="125D260869C3B34C" modified="2017-08-30" version="1">MWSFVKLVFLFVLATVFHWAFASIFSYWGLSVNILLAFAAAFCAVLKPAFGYPAAFFCGLFLDFFGTKLFGNNAFTFTVCACIVYNLSERFDFDAFFPQIVTVFGLTFLAGVLNSLLFLWFTSAALWPGFWSLLGGAFVSAVFAPVVFWLVRRVLGKGSICRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCL8</accession>
    <name>A0A1Y4DCL8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="6">RF MTase</shortName>
            <ecNumber evidence="6">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prmC</name>
        <name evidence="9" type="ORF">B5F75_05385</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56625">
        <property type="protein sequence ID" value="OUO56625"/>
        <property type="gene ID" value="B5F75_05385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="7">
        <location>
            <begin position="114"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="187"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="279" mass="30623" checksum="5640CAB9225F791F" modified="2017-08-30" version="1">MPTISHVLQGAVQRLEAAGSDEPQANAQWLLAHVLGVSRTWVLANGGEPFPADKEALFSRLLARKEAGEPLSHIVGMQPFCGLDIRVTPDVLTPRPETEELVERCAAQFERQGRYTFLDMCTGSGCIAVALANKFPNAAVLAVDISAAALRVAQENARLHRVDTRIQFLQSDLWENVMGTFDLIISNPPYIPTAQLAGLTREVKHEPRLALDGGEDGYAVTRPLCEAADGYLNPGGLLALELCQGQPWPLARGLMEIGWKAEVKKDIFNIERFVFARRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM5</accession>
    <name>A0A1Y4DCM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">B5F75_03150</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56857">
        <property type="protein sequence ID" value="OUO56857"/>
        <property type="gene ID" value="B5F75_03150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="9"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="405"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="501"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="277"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO56857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="597" mass="66631" checksum="D1D23E355C21B140" modified="2017-08-30" version="1">MFVCEDQYDVIVIGGGHAGCEAALAAAKLGAKTLLLSQSLDTVAQMSCNPSIGGIAKGQIVREIDALGGAMGRVTDHAALHYHMLNTGKGPAVHSPRVQCDKKVYQFTFKHFLELQPNLDIMQDEAVKISVSDNAVDGVLTLRNTFYHTKSVILTTGTFLAGTIHIGTEMFRGGRYNDMPSDGLAKNLREELKLNILRFKTGTPMRINARGLDYSKFRLQPSDNPLQPISHFTDVTEQSKRTFLSCYITRTTLETDKILRSNFQRSAMYSGNIHSLGPRYCPSVEDKIKKFPDVTSHPLFLEPEGFHTEEFYIQGFSTSMPEDVQRALIKSVPGMEKATITRPGYAIEYDFSDPRDLFPSLESKRIPGLFMAGQINGTTGYEEAGGQGIMAGINAALKVQGKEPFVLRRDEAYIGVLIDDLINKGVNEPYRMFTSRAEYRILLRNDNADLRLMPHAFKLGMLDKKYQAPFEKYKALCQKLIDHPNAPADEDETELFPWTVQKARTHADIYHKYAGYYERNKKDAERLAEMDSVKIPEGFDPSSVRGLLFESAQKLAAVKPQTLGQAGRIPGVTPADLQLLAVHIERFRRLKNAKAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN8</accession>
    <name>A0A1Y4DCN8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">B5F75_03295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56883">
        <property type="protein sequence ID" value="OUO56883"/>
        <property type="gene ID" value="B5F75_03295"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="36702" checksum="9F9A01BA43B4A483" modified="2017-08-30" version="1">MKIALDALGGDFGAKPNVLGALKAAKELKLEVILVGNEAVLREELKTLGYADLPKNISIVHAPQTIDMGAEPAKECRSKKNASIVVCANLVRRGQADAFVSAGHSGAAMVAALFGMGRIKGVQRPAIATPMPTYKGVSLLLDGGANADCKPIHLLQFAVMGSAYMQKVFDIPAPSVGILSIGEEETKGNFLVKHTIPHMREIGVNFKGTVEGRDVNTGDTDVIVCDGFVGNIVLKMAEGLAKTMIQMIKREIKKRPLAVLGALLAKGAFKAVKNHTNPDCYGGAPLVGVNGVAIISHGKSNDFAIFNAIKTAARLVEKDFIGDIAAKMAALKPTFEAIEKEIHQEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCX5</accession>
    <name>A0A1Y4DCX5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56967">
        <property type="protein sequence ID" value="OUO56967"/>
        <property type="gene ID" value="B5F75_03730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012915273" evidence="1">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="172" mass="18518" checksum="BAC59628B466BA7A" modified="2017-08-30" version="1">MKLNKFFALLATLAVSTAAFAGNSSSNSALIEQSVSSAAATVEEEAADPQILKNTQQALTMGFMIFDAHRDLNSMTETDQAIASLLESNIPATLNKIETSSDDVVDEIEPMIEQLTDLLLKNQTVYPAASYDRQAGVYITFLTAIMYANQKGLLLGKVSNILSAEIQSSFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCY1</accession>
    <name>A0A1Y4DCY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57024">
        <property type="protein sequence ID" value="OUO57024"/>
        <property type="gene ID" value="B5F75_04040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="869" mass="96582" checksum="5B9E05E2FCEB7E38" modified="2017-08-30" version="1">MPIHYLQPSFSGGEISPALHGRADSAAYASWLKTVRNFYIHPQGGASNRPGTLFMGQAKYEQKDCRIIPFVLGEEEAYVLELGEHYLRVYASGGRISSADGQPYEIETPYEAYDVRYLNYTQYDQTLFLTHPQYPPKQLRRVESGLFEFTDVPIKYGPFMLANSDKTKKMRAVLHQETEESVGVSATLSFLPISYPNMVAFVYFDGVRFFVGPDFGLDVGLMVTYFNRSFEAAGYKAYNLGGLVKIESPKDTGGDCNGKQLVINFHDGLLRPPVISFTQTLSGGSNKGQLISQGENQYQLESDFECFKPGHVGGRFALTHKVPSQMLTGTLGYEDSSASVKSGGDWKLRTTGEWTGKLELEMSGDMGKTWETIKFFSRETGDENLNTFGQLDDQNSLYYLRLTARQISGEAGFELQADSFRQEGIFVVKDFVNGQKVVVEVERPFGSDEWTDEWAEGSFSPAAGYPSCVFFYQDRLGLAGTQAEAQTIWFSKTGAYSDFGHARNTLEDSDSISVNLSGKKLNAIHSVAVSNKLLVFTAGSEWTISSSGALTPYNIQVQQQSERGASRTAPVMVGNKALYVQARGGVLRDFYYDYNSASYTSNDLTLYAKHIFFNREIREICYQQEPDNLIWCVLDDGTLAVLTYLAEQNVCAWSRHDTQGKYRSICTIPNRGYDEIWFAVERDGQYFIERLVQRLASKAPEDQLFLDAAVSRKSETAFSELDGLEHLEGKEVGVLADGSPLAGLVVRSGKIILPRPMNCVHAGLSYEAELQTLPAAFDRSDGTAQDRLRRLVSVTVKMLDSRGGQVGTENGPLNDIIQRGTENFNTPIALQTKDYVLALSGTHSLVPSVLFKQTDPLPVTLLAFISRIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCY2</accession>
    <name>A0A1Y4DCY2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aspS</name>
        <name evidence="9" type="ORF">B5F75_03250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56876">
        <property type="protein sequence ID" value="OUO56876"/>
        <property type="gene ID" value="B5F75_03250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="142"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="197"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="530"/>
            <end position="533"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="582" mass="65226" checksum="9504394EDF0F1C7B" modified="2017-08-30" version="1">MKRTNYCGDITASLLGTKQTLCGWVNSYRNHGGVLFIDVRDRSGICQVVVEPSKPFFAEASAVRNEYVVEVTGTVNRRIEGAVNKNMKTGEIEVVAEEFKVLNTSIPLPFDVDKSLSVAEEIRLKYRYLDLRNPHMYANLLLRHRIMQAARRYLDGQGFLEVETPILTRSTPEGARDYLVPSRVHHGEFYALPQSPQMFKQTLMASGIDRYFQLARCFRDEDLRADRQPEHTQIDMEMSFVTIDDIHEVVEGLMKEIFKTAGKDISVPFPKLSYHDAMEKYGSDKPDLRYSLEMKNVNDVFKNTGFKVFKEVLAAGGAIRALRGEKGAAYSRGHLDKLTELAKKNGAKGLVWLKVKDGALEGPSAKFFTPQEMSALKEAVSALDGDIILVGSDANLHTCQTFMGALRKELVKELPRQSEWAFAWITNFPLLEYIPEEDRWDAAHNPFTAPVEEDLPNLEKDPGSVRSYQFDLVLNGNELASGSVRNCRREVQERILALMKHSKEESARRFGMLLNALEAGAPPHGGIGLGLDRITALLAGEESIREVIAFPKTAQAVCPLTDSPNVVDDIQLKELGIEISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD50</accession>
    <name>A0A1Y4DD50_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57007">
        <property type="protein sequence ID" value="OUO57007"/>
        <property type="gene ID" value="B5F75_03940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="13253" checksum="F723388525C67AF8" modified="2017-08-30" version="1">MKKVVLIEDSKVLAHALIGALKVEGIEAHWAENGVSGVQLAKQLKPDLVLLDLMLPKLSGFDVCKLLKTDDGTWRIPVVIMSTLSDPQSRDRATDAGADYFIPKPYDLASTLAEIKKILKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD57</accession>
    <name>A0A1Y4DD57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_04235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57063">
        <property type="protein sequence ID" value="OUO57063"/>
        <property type="gene ID" value="B5F75_04235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="157"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="296" mass="33086" checksum="7B472C5B1EB36604" modified="2017-08-30" version="1">MNNLVFTLGLNLLLAVGMFSVFLTIFGLLSPKPKKEEIVDVAVRRFKSTSSFARLKPEEKILDRLAVFCLHNFHLEKSLEEMHMQLGSPDTPQPVDILYTKVIAALVIPAAIMLLFQAIWPVLLVPVCFMVPDVLIKSKIQKRQAEILGNFSTTVDLAALIIESGLDYLTAFERIIKIAKEKTILEEELEKTINEIKLGYSRREALERFSARTGVAEVRSLVSLIIQSDELGTSLVDLLRNFSSDLRSRRLSRAEKLAAQASTKMLFPLFVFIFPTIFALILAPMIGSLISGGMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD82</accession>
    <name>A0A1Y4DD82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57037">
        <property type="protein sequence ID" value="OUO57037"/>
        <property type="gene ID" value="B5F75_04105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012734549" evidence="1">
        <location>
            <begin position="22"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="420" mass="47956" checksum="75507E2FA4D5EADB" modified="2017-08-30" version="1">MKNLVLLLFFILSVPAAPVWAQKNLVPAGRALLTNAPKTAARACGSASSFGATTAARALTRFPAAQAVPPASRLKFQHSLQRRALFQVDKTRQAKNDELLRQIDQTWEQNEDLIYGGAYETLYTPLQENTPFAYQNNQIVLAASKSLLQKTQWLKQRKGQGQAELGYVSSGNLIKQLAAKVEDSHIVFLGEFHYVPEIQRAVGQLLYALKDRNQGRRIVLFTEFIDLPPTAREGAPASLASYYRRASEFPTERIQEDDPHLFKRLDYARDLFEILLDDHFEIYPLEDRKLCSMIYQEEGLLRDMQVSALAITLRNKTWARMMEHKMAQIRKTDPDALFVVYAGMAHTSWIMPYALPKFFAKEKTSVVEFSVGEPSEINTLCGVWDREHPYFRKQALFYWQGREARLLGRQTGFDYALILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDA0</accession>
    <name>A0A1Y4DDA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPR_MalT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57006">
        <property type="protein sequence ID" value="OUO57006"/>
        <property type="gene ID" value="B5F75_03935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="TPR_MalT" evidence="3">
        <location>
            <begin position="210"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="364" mass="40613" checksum="E9BDE5B9F006FAA9" modified="2017-08-30" version="1">MPVTKKQPAKRKAQLNVTELEELLENNRPSEALEKLLAVRTKDAAAWFLTGEAQRQLGAFEPALASYAKALQLADEAETRMDVLLAMAACYRTLGHSAAAYELAQEAFQMAQELEYDEFVVRAMQEMGMALRAWGRLEEALDLLDAVLAAYTQLQDYAGMSFIHWAKGGIFRLQGHFQEGIAQFKQAISLAKKAGDGISLAYGYCGLAGISRICGKIDDCVKNYKLAEKIFRKSEDLFGKAYTNCGMANGLRQQGKYDEALRHYNVADKLYSSIHDTVDLGFVKWGRADILKRKNKMEAALQDLQQARELFDNSDETRGQILTKLSLAQVLYALGQTQEAEELYEAGVSQARAEGLHTYLESYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDA1</accession>
    <name>A0A1Y4DDA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56612">
        <property type="protein sequence ID" value="OUO56612"/>
        <property type="gene ID" value="B5F75_05320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="176" mass="19462" checksum="204A07814535DB46" modified="2017-08-30" version="1">MKKGFTLIELLVVVLIIGILAAVALPQYEKSVAKAKATEAVTLFRSIAKAKQLYYLSNGKYTRELDSLDIEVPNIGVDFGYGVNNFKGNHMQFYFEGGNSQTETMIGKAYPIKATYNNKQFAIYMKLVPPNGELTIWCTSDYDPNYGFGNWKNFDASATASPICQGISGKKNGLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDE3</accession>
    <name>A0A1Y4DDE3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56895">
        <property type="protein sequence ID" value="OUO56895"/>
        <property type="gene ID" value="B5F75_03365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="172" mass="19434" checksum="3B54E6835ECE4489" modified="2017-08-30" version="1">MTTPLIRPARPADLPRIRQIIRAAKSLLLSRHVDQWQDGYPNEAVLADDIARGKGYAVETNGAVHGYFALSFEDEEPYRVITQGAWLTDGHYCVLHRLALTETLRGTGAAGLIIDFWERQTRAQGIRSLRADTHPQNHPVRHLLLQHGFTDCGVIFVRQSQARHAFEKVLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDN6</accession>
    <name>A0A1Y4DDN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57234">
        <property type="protein sequence ID" value="OUO57234"/>
        <property type="gene ID" value="B5F75_00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="16"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="268" mass="30995" checksum="C1E337D0ED2241D4" modified="2017-08-30" version="1">MITIAKTPVKTLLSKSKIPGFDYVINPYVGCPHKCVYCYAEYMRKFTGHAEEWGDFLDVKECPVPLRPAQLFRTRVMLSSVTDPYNPYEKQYELTRRLLKQLIVCQAQVHILTKSALVLRDMDLLKQMPSCEVAFSIASADESFRQLAEPGASSLQDRLDALQTLHQNGIHTAVMAAPLFPGISDWRKIIEQTRPYAERYTFDSLNMRPAYQRKVMNFVARHYPQALPLYSEIYLQESTDYWQKLREEITAYCLQHGIQGEVYFGHSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU2</accession>
    <name>A0A1Y4DDU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphoenolpyruvate--protein phosphotransferase</fullName>
            <ecNumber evidence="5">2.7.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">B5F75_00360</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57267">
        <property type="protein sequence ID" value="OUO57267"/>
        <property type="gene ID" value="B5F75_00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001127">
        <property type="entry name" value="PTS_EIIA_1_perm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00358">
        <property type="entry name" value="PTS_EIIA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00830">
        <property type="entry name" value="PTBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51093">
        <property type="entry name" value="PTS_EIIA_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00371">
        <property type="entry name" value="PTS_EIIA_TYPE_1_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-1" evidence="12">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="HPr" evidence="13">
        <location>
            <begin position="174"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="835" mass="88335" checksum="FC1641E511C2F495" modified="2017-08-30" version="1">MEVTFEGVFMSNTFTVYSPVAGVAVPLEKVPDPVFSEHMLGDGIAIDPVEDTVFALFDGKIINFNKESHAFVLGANGVEVLVHVGLETVTLKGEGFTPLAKTGDMVKKGQPLLKFDPNVIAQKAASPLVMVVVTTPPESSVANKADGILKVGDPLFQLPSVQAVEASSSDEPLTQSAPITVINPNGLHARPAGVLAQMALKYPFTVEIVKQGTAANAKSVVAIMGMALAYNDTVTLRAGGPQDQAKAFLAQLETAFKEGLGENTFPAPAPTAAPASSEQKALTACAGLAFGKAFLYHAADIAFEENAADSAAEQKRLTDTLQAVIAETESKIASEKNEEAKAILGAHLSILQDPELAKQAQQSVQAGKSAAYAISEAIRASIGVLQKTANAFLMERAADLKDLRRALLLRLGGKSQTAPQVPQGCILVAEELLPSEASALEGQVAGVLLAAGSPTAHASIILRNMGIPTVVRGGQKVLDIPAGTSICLDADHALFTANPTPQQQADFSKRLDQHRQERLAQEQAAHEKACTQDGVQIWVEGNVSNEKEAARAITNGADGLGLVRTEFLFHGRTQAPSQQEQQTAYQAVVNAAQGRPVTLRTLDAGGDKPLPFVHIPKEENPIVGIRGIRAFKHNEAFFRTQLRAMLSVAPQTGNLRIMLPMVAFSEEMDFFRQVILEEKQALGVKNNVQIGMMVEVPSAALSSRQMAERADFFSIGTNDLTQYTLAIDRGHKELSVLADSLHPAVLRLIGLTCEGARQQGKPVAVCGAMAGDLTAIPFLIGLGVTELAVGAGAVAQIKALVRRLDSRRCGQAAQKAVTLASAKEVRALAKAEFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX1</accession>
    <name>A0A1Y4DDX1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_00615</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57313">
        <property type="protein sequence ID" value="OUO57313"/>
        <property type="gene ID" value="B5F75_00615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="324"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="417" mass="47490" checksum="4FAD34411D9AF1BE" modified="2017-08-30" version="1">MKLPDLISTGWAEITSHKMRSFLSVFAIAIGIATFFYTLSVLSQRYRDINRTAEISGKGRLDTSIEAPLSMDQYQQLLSSLPEGSSLAFRTNEYITRAIYKGQTLTGFFVEGILPSFQDSAFAYQVEGRFFNWKDIINKHRVALIVVYPRDKKERRVFSAPTWAPDKDRIDLKEFVKRINLLNQSITIEDQSFTVVGILRAPTVDKDFRFRGDQETMQQIFIPYSTWYDILPSWRDYYETKIRIVAGSETNANQASTALSSFLHHQFGTNFQFSINFFRDKLNLDRQAAWKNLRSMIFIGLIAMIAGGIGIMNITMVVIFSRTREIGIRRALGATRFDILIQFLVEALLLGLCGAMGGMLLGYLAVVHMADNADQMTFSWWVVAISIFIALATSFLFALYPAYQASKLKPVDALKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY7</accession>
    <name>A0A1Y4DDY7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ORF">B5F75_00640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57317">
        <property type="protein sequence ID" value="OUO57317"/>
        <property type="gene ID" value="B5F75_00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="25576" checksum="AA8210733CCAC1C2" modified="2017-08-30" version="1">MLYIVPTPIGNLQDITLRALEVLKTADAVLCEDTRRTQILLSHFGLSKPTYRYNENDDRSVARCLEALKSGKTCALVSDCGTPCISDPGWKLVKAAVAEGIKVSSLPGPSAVACALAGAGITGGAFTFLGFLPRKPGKAAKLIAAAYALQHPVVLYESPYRVVKMLQLIADTLGNETPVILARELSKVYEEWLRGTAQQLAETLGKKQKVQGEFVMIIDRPAAAEREEEHAQDAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDZ0</accession>
    <name>A0A1Y4DDZ0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Reactive intermediate/imine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57334">
        <property type="protein sequence ID" value="OUO57334"/>
        <property type="gene ID" value="B5F75_00730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="125" mass="13489" checksum="F881FE3B67151B2E" modified="2017-08-30" version="1">MKKVINSNNAPKAIGPYSQAIDDGGFVFTSGVLPIDPVTGEIYSGDVQVQTELILKNLENILKEAGCALKHVVKTTVFMTDLTKFAEMNAVYASFFKDNPPARSTIQVVALPKGSMVEIEAIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE11</accession>
    <name>A0A1Y4DE11_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Electron transfer flavoprotein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_00910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57364">
        <property type="protein sequence ID" value="OUO57364"/>
        <property type="gene ID" value="B5F75_00910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="396" mass="42094" checksum="CA941A46F6246757" modified="2017-08-30" version="1">MIQVASNCVGCGKCVGACPFGALSLVNRKAVPNANCTMCGACVSVCPVKALSLPASGAVKKDLSAYKGVWVFIEIADDGKTQKVRPVGFELLSKGRELANQLGEELCAVVIGDNVSQYYAELSQYGTDKIYAVNGPEYHHYNTLAYANAMVTLIKKYNPSVVLYPSTYIGRDLSPRISSELFVGLTADCTGLSVKDGNLIQTRPAFGGNIMADIKCPDYRPQMSTVRPNVFKKVVTTPGKMAQVVTEAIAVPPQAAKVRIINTHFDEVSAMDKLDEAEVVIAGGRGMKDKSGFALLEELAADLGGAVGASRAAIDLGLKPKEKQIGQSGVTVASKLYVACGISGAVQHIVGMEHSDVIIGINKDANAPIFNVCKYGFVGDARQILPRIIEQVKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE23</accession>
    <name>A0A1Y4DE23_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56902">
        <property type="protein sequence ID" value="OUO56902"/>
        <property type="gene ID" value="B5F75_03400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="65" mass="7395" checksum="8B504F4CD7C5853B" modified="2017-08-30" version="1">MPVHPIGLGHIVSVLLHTNKTAGEPPCYTKKYFPFVLLPFIRPFVLFLKSLSNDKALLLFERSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE74</accession>
    <name>A0A1Y4DE74_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="6">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="6">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="6">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">msrA</name>
        <name evidence="8" type="ORF">B5F75_00750</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 6">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57336">
        <property type="protein sequence ID" value="OUO57336"/>
        <property type="gene ID" value="B5F75_00750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="7">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="284" mass="32024" checksum="D22C2FCF18840689" modified="2017-08-30" version="1">MKPLNPEEKHILLEKGTEPPFSGKYYRHKAAGRYLCRQCGAPLYRSEDKFNSACGWPSFDDEIPGAVRRVPDADGVRTEIVCARCGGHLGHVFEGEHLTAKNVRHCVNSLSLVFQPAGEETTSPRGEVAIFAGGCFWGVEHLMKNFPGILQIEPGYTGGYEPHPTYEQVCSQLTGHAEAVRIVFDPKQVSYETLVKGFMEIHDPTQQNRQGPDVGSQYRSEIFYTTQAQRQTALAVIALLRSKGYPVVTQVTEASSFWPAEDYHHRYYERTGAQPYCHRRVKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE89</accession>
    <name>A0A1Y4DE89_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56972">
        <property type="protein sequence ID" value="OUO56972"/>
        <property type="gene ID" value="B5F75_03755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="244" mass="26457" checksum="4A1D04659928449D" modified="2017-08-30" version="1">MKNKKGFTLTEILLAVMIVGIIGVALAALTTAASRESGVGRSKILLRNNLSIALRQLRDDIHASSRVMYVRGRIDSSSEGAVTPLLLLAKNINLNNNAINSMVTPSYVTYCFVTGGTTATPTGALSKGTIYRRESSSVPTWDGIAPVCGTPDTDDNFEVFLHNVKFIPPIGSSGDSKYYPVPLFRLSGSDAEYSEKDAVSVDWRRKDLASVLVLKIITELDSTPIVNDVVEETFILPNGFRVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE92</accession>
    <name>A0A1Y4DE92_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsF</name>
        <name evidence="6" type="ORF">B5F75_00865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57356">
        <property type="protein sequence ID" value="OUO57356"/>
        <property type="gene ID" value="B5F75_00865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="139" mass="15760" checksum="8ADC86AE920E1272" modified="2017-08-30" version="1">MSKAESIRRNSPGLEARGGFLALQNAIKKNNWYMRTYESVIIVKPQLSDGEVGEFVTKAKDLITKNGGEVVSEEKLGRRKFTHEVNHVRDGFYLYLKFKAEPKFVKVFEDALKLNEKVLRSMTMNSVEVKVKPAPAVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE93</accession>
    <name>A0A1Y4DE93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57417">
        <property type="protein sequence ID" value="OUO57417"/>
        <property type="gene ID" value="B5F75_01195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="20733" checksum="FB849DB22A83547B" modified="2017-08-30" version="1">MVIWFLFGAMCMLVVLLMLAYVKFVSLNKAAQNAWQQLDNNMKNRAELIPSLALSAASFPELDREFIYELSHLKDACRKTATLQERVQLESDITKKFKKVFTAAMQHPELKDDEHFLKLQRSIIHAEGKVQSSKKKYNSAARDFNTITGVIPLNLIAKMFEFEPYEYFDFDPSLEKVMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC0</accession>
    <name>A0A1Y4DEC0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56982">
        <property type="protein sequence ID" value="OUO56982"/>
        <property type="gene ID" value="B5F75_03805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="534" mass="59014" checksum="343A6EE3D9108E39" modified="2017-08-30" version="1">MSFSETLIGKNMNAHPDCLGIYIGIDEMYIAQSSKKDSGTVLESLVRVPINSVDKTLLKPLDLNEAFFSMDNWLEALGKVTSKKKWKTNKVVVSLAPAFCLLRHFVIPAAIERKMWKSSIPLQARKYIHFPFEKAEYAYHVYEFETAATKQKRLGVVFAMTTKLIIERLQKGLKAAGLELVSVEPSSLSMGRAFNDSDKEAIGPGGRIYSFFGKDMASFVFLNENAPVLLREVEIYGSLPAERRRFEITNCTEFIAKQLEKDPFEEAVIMGHDTEQWIPALEADSKKPVRKWDLREVYGIETNSAGEIAAIGASIKFYDHKTPDLDFTKGTRLSDYEFNASLTAWKIAAVIIVIFLLLIGKGWLGVQSKASELARTKASNRQTIADFEGLTANQIQSNLSKMKSQNGNLSTLLSGDSVLVPVLEEIVNTIPQEMWITKLSYTDSFPSKGASSRKIDMEGVIKTGKDGRADLALGNQFKDALVQQPIFQQICGKTATIRYVNVAGAGTSAASAGGRETTGQETSFVFTCGKEGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEJ5</accession>
    <name>A0A1Y4DEJ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">lnt</name>
        <name evidence="10" type="ORF">B5F75_02070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57583">
        <property type="protein sequence ID" value="OUO57583"/>
        <property type="gene ID" value="B5F75_02070"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="542"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="285"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="564" mass="63067" checksum="4093A16C35F26144" modified="2017-08-30" version="1">MQSVGPSRLPRQRLPDFVLIFMRGFRQTIAEQDAFLAQNRWSIFFKNSFSVLGRYLFLLLCAGATAWLVYQSYPSVSRHALAWFALAPFIWGVTKTKGFWSSFLYGWLTAFLFNAGIFYWIYYTCLHGGGLSQGLSLAAWLGLSGLLAVQFALFGGSCYFLKKTGPFFPLLAACGFVTLEWLHQTLAFYGLGFPWIMLGYTQWNAPEMLQLAAFTGVYGISFIVAFTGASLGWAFATKGVKDGVWHMVAAAVVFLAAYTYGHYTLPDASQKRPFKPLLSLSTALLQPNIDQYKKWSPQYEAEILQTLQAQGMALEGKGVRLMVWPESAVPGALTEEPYWTLFKEIAAKTDAYQFIGSNVEEDGKQYVGAYLLAPQSEKLQSYRKTKLVPFGEYIPLEGLVHRIFKDVAVLGELGSFTPGARGQKPLDLGGVAVGETICYESIYPQLWLSQNRQGAKLFINVTNDAWFFDTAAPYQHLAVNVLRAVETGRPVLRAANTGFSAVIDPFGRIEKQSRLFTQEILQASIPLALNEQKNFYTQWGDWFAWLCAALFATLLISTVVFSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK3</accession>
    <name>A0A1Y4DEK3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57593">
        <property type="protein sequence ID" value="OUO57593"/>
        <property type="gene ID" value="B5F75_02120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="60"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="373" mass="42844" checksum="57F7EEFC70F8D805" modified="2017-08-30" version="1">MIKNPFPNEIYLARTHAHTPDLRDEYFRDQTKIIHSLPFRRLKHKTQVFFAPNNDHICTRIEHVLHVATIAATICRGLNKSGNWELSEDMAYAIGLGHDIGHAPFGHEGERAIDACIRPKRFLHELNSYRVVEHLANYGEGLNLTFAVKDGIICHCGEDFANNKLRPADKPNDLEKITGRNQMPSTYEGCIVRLSDKIAYLGRDIEDAIKADLITTNDIPKNVREEIGTSNGEIINTLTLDLINHSKDKDFIGFSDDKFALLSQLRTFNYERIYHNEQMRQRKETIDKCIRDLFDYFRTIFNRYGFDYEAYAKEGKNTAKSFANYMKSMTKVYHQDPAQIDTAIADYIAGMTDSFALSVMEDVILPNSIKFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ3</accession>
    <name>A0A1Y4DEQ3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DedA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57385">
        <property type="protein sequence ID" value="OUO57385"/>
        <property type="gene ID" value="B5F75_01020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032818">
        <property type="entry name" value="DedA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30353">
        <property type="entry name" value="PTHR30353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="216" mass="24226" checksum="04B1E2DF231E2E94" modified="2017-08-30" version="1">MELLSQVLDIFLHLDVHLNAWAAWMGVWLYVVIFAVVFCETGLVVTPFLPGDSLLFACGALAAAEGSSINLYWLIPVIFAAAVLGDFCNYEIGKWLGPKVFTKEDSIFLNKDHLNKAHAFYEKYGGKTIILARFIPIIRTFAPFVAGIGKMTYFHFASYNLIGAALWVLAFTLGGYFFADLPVVQNHFHYVVVAIIVISLLPAVYEFWNAHRQPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV8</accession>
    <name>A0A1Y4DEV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase_M3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_01345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57445">
        <property type="protein sequence ID" value="OUO57445"/>
        <property type="gene ID" value="B5F75_01345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013006082" description="Peptidase_M3 domain-containing protein" evidence="9">
        <location>
            <begin position="20"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="232"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="682" mass="78225" checksum="04E849ADFA30EFF5" modified="2017-08-30" version="1">MHKMMMSVAALALPCAAFAGAYGDMFKNGHLRFDYTPQEISSLEARAAKELDVNLNFLVRIPAQDRDFENTVLALENAYTSYWFVPKNLSLLAYFHENADVRAAAARLEAKGSQTKAAVFARKDVYKALKEYADKKPALAHEEARLLSKWLERYERAGMALSDEAAAEYARLNNERLQKITQYNVNLNNYQDELVVSREELEGLGDTFINRLARTPEGKYIVTLKYPDYNPFMASAKSEKARKALQEKFARRGGEENVRLLEDTLELRRKQAALLGYAQYPDYVLPVRMAKNYKTLEKFLKNLQKEVTPLAQKEMQDYLKLKEEITGQKAREMTAWELPYWSNEYKKKYYRVDNDKIKEYLPADRVREGMFEIFGHLFGVTFEKADLPVWHPDVLVYQIKDAKTGELISNFYLDLYPRDGKYTHAATWSFVDRFELPDGSYQTPSVVIAANFTPAGNGVPPLLEHSEVETLFHEFGHVLQMSMATSKYATLTGDNVAWDYIETHSQLLENWAWQPEVLARISAHYQTGEPMPKEMIDALIKSKHAGEATAFLRQNFLGQFDLAAHAAQKRVDSTRLYAQMMQDITGVPMTKGTYPQASFGHIMSLTDPYDVGYYVYAWSLVIAQDIFGEFQKQGIFNEELGARLRQYIYTPGTVYDENEMVETFLGRPYNDEAFLKSLGVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEW4</accession>
    <name>A0A1Y4DEW4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cysteine synthase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_01685</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57713">
        <property type="protein sequence ID" value="OUO57713"/>
        <property type="gene ID" value="B5F75_01685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="7"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="3">
        <location>
            <begin position="175"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="32159" checksum="F7ECECBECA2A52E1" modified="2017-08-30" version="1">MKINSLEQAIGRTPLAAVTRLNPGPGHVWAKLEMFNPFSVKDRAALFMLNAAEQEGRLLPGAMIVEPTSGNTGIALAFLAAARGYKIVLTMPENMSAERMKLLKALGARLVLTPKAKGMKGAIDEAEKILRQTPGSFMPSQFENTHNAQAHEQTTGPEIWEDLEGNVDVFVAGVGTGGTLTGTGRFLKRKNPQLRLVAVEPADSPLLSQGRSGPHGLQGIGANFVPPVLDRSLIDEIIPVQTQDAVQTARSLAATQGILPGISGGAALWAALQVAARTQSAGKNIVVLLPDSGERYLSTELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEY3</accession>
    <name>A0A1Y4DEY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57202">
        <property type="protein sequence ID" value="OUO57202"/>
        <property type="gene ID" value="B5F75_00015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="401" mass="45657" checksum="6696F4F44261624E" modified="2017-08-30" version="1">MILWAMPDSGDKTKEVYASFIELFKKENPSIDVTVRVFTRNVLWRRMFTIKHPTHEEEVPDLVQIPHYWTALLVREGVAENLSELDPGLSLANCLVPLKPHCYQPGTKDIYSYPWWFDLSALHYRADHLKLVTSRPEHDLATWEGLLNICQALREQFKDTPGYYPMQNSDWRGSLSVRNALPCIWGRGGDLLSPDLSSTLVGTKAFKEGIRDYVNLALKNYMPILRERGSLGTIVSGKASMMISRKQGVSTFNARKGIRVRTLPVPTTGTTYYSYLAGMNLFVNKLSQEKKNALKFIKFCARPENQLRYAAMIDAFPAFEDAFEQFIFSSSQRLQTYSNILASARTLPNITVTGTIMEILKRILAVCATQIVEERFTQASLDRELDLAAKEIEYLLSIYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEZ5</accession>
    <name>A0A1Y4DEZ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">B5F75_02660</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57694">
        <property type="protein sequence ID" value="OUO57694"/>
        <property type="gene ID" value="B5F75_02660"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="295" mass="32236" checksum="4962B367202E21C2" modified="2017-08-30" version="1">MFRGIYTALATPMKPNGSVDYDALERLLRAQLSAGVDGIVLLGTTAEAATLSAGEKTEILQFCVPLIKGRAKIIIGTGTNATSSTLENTRAALAFEPDGVLVVTPYYNKPNPNGLIEHYKQVAALGKPIVLYHIPGRTGLKLSNAVFDRLLAEVPQIAGIKESDYDMAHVMDMAVKYAHRLNYICGNDDLFPQFLAMNASGIISAGANVLAPAFVQIYKLFLQGQTKKSFDLFAQLYPLVKACYLETNPTCVKYMLEKIGFGTQTVRLPLGTISEENKQKIDRLLETADPTFFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF01</accession>
    <name>A0A1Y4DF01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpB</name>
        <name evidence="13" type="ORF">B5F75_02460</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57656">
        <property type="protein sequence ID" value="OUO57656"/>
        <property type="gene ID" value="B5F75_02460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="188"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="253" mass="27248" checksum="88482536F7DBFCAA" modified="2017-08-30" version="1">MDVAEIIAHHILDHDWGVTLDGFRLPITTHSVTLLAISVVLLLGLSWIARLGPSRAGRLLKTLMEEYVSFIRDGIVLPNMGKEGKSFLPYFCTLFLFVLCSALAGLIPNMKTATANISVTAALALCSGGLILYCGLKFHGPIGFLKGFIPSGTPGWLVPLIFPLEVVSMIIKVCVLAIRLFANMLSGHMVLICLLLIIFVVGQMHIAAGAGALLPAMGLELFMTCLELLVAFLQAYVFTLLTSIFAGSVIHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF38</accession>
    <name>A0A1Y4DF38_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57717">
        <property type="protein sequence ID" value="OUO57717"/>
        <property type="gene ID" value="B5F75_02410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016440">
        <property type="entry name" value="Rubredoxin-O_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005243">
        <property type="entry name" value="ROO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="251"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="397" mass="44770" checksum="2D0B3AFC81F75E91" modified="2017-08-30" version="1">MEAVKISEHVYWVGAIDWNIRDFHGYSTKRGTTYNAYLVMGEKPTLIDTVKKEFYGEMMERIQSVIDPKKIKIIISNHSEMDHSGALPQAVNYIQPEEVYVSDMGFKDITAQFHCDLKLKTVKTGDRIDVGGDTISFVEARMLHWPDSMFSYLEKENVLFTNDVFGMHYATSKLFDDENEERLWLYEAEKYYANIVLPYSDIVLRFLGQVQKMGLSPRMIAPDHGFIWRKDPSKIISLYAKWASQAPKNKAIVVYDTMWGSTEKMANYITDGLRAGGTEVKQLSMHSNHRSDVATELLDSSALLIGSPVLNSQIFPAMADVLCYLKGLRKKGLVGAAFGSYGWNGSPVDELTKTLESMNVEVVAPAVKSLFVPDEKVKQACRDLGLAVSKKLAEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF41</accession>
    <name>A0A1Y4DF41_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57706">
        <property type="protein sequence ID" value="OUO57706"/>
        <property type="gene ID" value="B5F75_00785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="45539" checksum="69E85275F39BB5DB" modified="2017-08-30" version="1">MPSEFLKRIPKADLHVHLDGSLRLSTLIELSKKEGVELPDYTEKGLRQKVFKDKYASLVEYLKGFSYTGAVMQNAENIERIAYELGQDAIAEGVRYLEVRFAPQLHANEKLTAQEAVRAVVCGLRRAQKEHNSSAAVKKGEDLEFYFGIIACAMRNFNQFMSPYYAGLIKALSQSSKSEIFSIASLELAKMVVKLAKEEKLPVVGFDLAGEEAGYPAADHLDAYRYVHKHFIRKTVHSGEAYGPESIFQAITDCYANRLGHGTHLFAAEMIKDKKVKNKEEYVNSLADYIASERIGIEVCLTSNLQTLPQIKSVKDHPIKEMIKRGLPVSINTDNRLVSNTTVTKEMELLVRNVNLTPKDLKNIVIAGFKSGFFPGSYIEKRRFVRKVIDRYNALAKEYGIPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFC5</accession>
    <name>A0A1Y4DFC5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="10" type="ORF">B5F75_02340</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57635">
        <property type="protein sequence ID" value="OUO57635"/>
        <property type="gene ID" value="B5F75_02340"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="143"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="235"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="46"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="266"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="353"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="429" mass="48173" checksum="53D3DAC9249DE697" modified="2017-08-30" version="1">MLDIKYIVANPEEVKKRLSLRKPELAVQIDGVLEKYSAYKTVLARVEELRAKRNEMSKSIGKIKKEQGDDAAKEAMAQVGKLKEEMAVKEAEMEPLKKEINDLLLSIPNLPNEHIPVGVSDADNPEYLPCTIPLPKFNFKPLDHQAVGEKLGILDFEAAAALSGSRFALFKGDGARLERAIISFMLDMHAKKGYTEILPPVIVNEDILIGTGQLPKFREDMYELVGEPKQFLISTAEIPLTNLNRIRVIPEAELPIKLTAYSPCFRKESGTYGKDTRGLIRNHQFDKVELVMLSKPEHSYQMLEIMVSDAQEILKELGLPYHVVELCSGDIGFSSAKTYDIEVWMPSENRFREISSCSNCLDFQARRMGLRYKNAQGKQEYVHTLNGSGLAVGRTFAAILENFQQADGSVIIPPALRPYFGKDKIEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFH1</accession>
    <name>A0A1Y4DFH1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsT</name>
        <name evidence="10" type="ORF">B5F75_01055</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57392">
        <property type="protein sequence ID" value="OUO57392"/>
        <property type="gene ID" value="B5F75_01055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="92" mass="9927" checksum="E4D3FC41D4BE39B2" modified="2017-08-30" version="1">MAKLKTGRHTSAIKAQRQAEKRTSANKGLTKKVRLATKAVVAAAKTKAATLKEDLKKAESCIDKAAKKSVMHWKTAARKKSRLAKAANKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFJ5</accession>
    <name>A0A1Y4DFJ5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57412">
        <property type="protein sequence ID" value="OUO57412"/>
        <property type="gene ID" value="B5F75_01165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010298">
        <property type="entry name" value="DUF901"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05991">
        <property type="entry name" value="NYN_YacP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="136" mass="15793" checksum="4BADAFA565460A8C" modified="2017-08-30" version="1">MYVTTKPTIYLIDGLNLVRSFLYEFARTEEEVTADFLDFLSEISQDEHYAMHQYEVIFDGSFRPVGPLYRGGVHISFSEEDSADQIIYERAAYLSQSGSRVIAVTDDRQLQQALKELGVKTFFCRKFYNSLKTFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFS5</accession>
    <name>A0A1Y4DFS5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57512">
        <property type="protein sequence ID" value="OUO57512"/>
        <property type="gene ID" value="B5F75_01700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="248" mass="27985" checksum="0E9A68203F7568CA" modified="2017-08-30" version="1">MLYSKPRSCDVLVEHGRATQSALPRRFTVCVWNWQKSKQKEWASEFSRLAQAADLFLAQEVRRSPAVKEVMEKTAYHWNGAVSFFSLKGKNPIGVATGCIANPLQVSFAATSREPVFRIPKMTLATLIPIQNAKRPLLVVNLHAINFTGIRAFEKNLRGAAEILLDYNGPILLGGDFNSWNHKRLRLLHCIIRSAGLQEVPFEPDLRSRWMGKPLDYLFVRGLKVLASGVRVTRGSDHNPLLARLEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFW2</accession>
    <name>A0A1Y4DFW2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc</name>
        <name evidence="5" type="ORF">B5F75_01965</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57562">
        <property type="protein sequence ID" value="OUO57562"/>
        <property type="gene ID" value="B5F75_01965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="4">
        <location>
            <begin position="518"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="181"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="430"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="677"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="845"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1159" mass="128864" checksum="8751BF3105D1D778" modified="2017-08-30" version="1">MYLKAIEIIGFKSFADKSRLDFEPGITCVVGPNGCGKSNVIDSVRWAIGEMSWKSLRSSSMVDIIFNGTAKRAPLNMAQVSMVFDNASRQLPLDFNEITVTRKIFRSGESEYYLNKVQCRLRDIRDLFLDTGIGGEGYAIIDQGGVESVLSASPEQRREMFEEVAGVSKYKAKREECIKRLERVDLDLARLSDTVALIEEQIKKLDSEARKARLYQRYREELKESEIAISVCSIKEADGLIAKHTGELEPVLRKLEDLEARISAQEGAAAALDLNLTHKQKEAAEFNEKISASKYQVGLLEGAITNCGNLTAELTAQIAASGAEAQRGQSRLQELAPAIAKLKEQLAAVSAELAPLQEQYNKQVASSQQLETDLRNTEAQSQRISGDLMALVRKQMEVSNRISLEESSAQRENEDLITAEKTSQEQTARAEQITRTLEEISARAAAKQAEADQARGAISAGEEDLRKLQTQRAALNEKLSAVKAARAALAAKLEMIQTQGKNDPYWVGAKAVAQSGLPGVKGTLRKALKYPASLAVAVEEAFGKYLDAVLCQDDNALQQALSVLKQHGKARAKFIVLSHVPQTAAAETGTLKKQLSYASELEDLINFIIGGYSYESGTVTGGFFVSGGAADVRAPEAYWGEEETVRGEMEAKAAEEDAVSKEIISNYDALTRADETLKNLRAKSQEAVVALNVVQNERANKEQELRSVQDALQRAAQRKQEITLRVEGRKKNAETLKQNLEELKNSQAQLTKQGEELKAKQAQLREQSEKIKSEIGTLNARLYEVKIKKNNVELDLKSTEYEFNSLTENEGKRNEKIASSNLRLKSLAEEKLSTQAKLSAERDTLAKLEVDEHKMRADLEALKKEYSDKTAALNACKKESSELAIKKNDLENALANARRQRTTVTNNLFESWNITPEEAQMNYGDKTVDYERVKMMRKRIENMGAVNMTAPEEYDALTERNTFLRTQMADLDGAKKDLKSAINKINQTTRENFKYTFEQVRTHFKNIYQTLFRGGECDLVLTQPENLLETGIEIYAQPPGKKLLNISSMSGGEKTLTAMSLLFAFFTHNPSPFCIMDEADAALDEANVERYVNLIKEFSKTTQFIVVTHNKRTMEAARMLYGITMEESGVSKVLSVNLADRSNPEDIKKKEAIEALAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG73</accession>
    <name>A0A1Y4DG73_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56659">
        <property type="protein sequence ID" value="OUO56659"/>
        <property type="gene ID" value="B5F75_05565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="213" mass="24076" checksum="BCFB0193FA1520F7" modified="2017-08-30" version="1">MAPMENKDGQIESSTSSMPPVIPSPSLPEEFLFWKNRIQEISDDYQHFKEQVEQLAAISDERQKLAEEANIKQVYLSNRIKQIERNLSRQTKNNIELLGIFVTLFTFISVSASVALQIKGVYHASLFISVFCLCLFAFLHVFHDFIQASDPQRGFKKLCGICFFVFLIAVIMGGFCWTGEREKSSTETHATASLKGENSLTPQLNVATPTKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGC8</accession>
    <name>A0A1Y4DGC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57712">
        <property type="protein sequence ID" value="OUO57712"/>
        <property type="gene ID" value="B5F75_01485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="166" mass="18832" checksum="AD2ADF0323BC3116" modified="2017-08-30" version="1">MEAILKRRSIRQFTNQPIAQDDLNTLLRAAMMAPTARNCQEWEFVVVRNKETFKKMMHVHPYAKMLEQADCAIIVCGNTQREHAPGYWMADCGAATQNILLAATSLGIGSVWLGVYPNEERMKGLSQLLGLPDYVKPLNIIALGYPAEKKEEVDRFDPAKIHTEKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGK2</accession>
    <name>A0A1Y4DGK2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">B5F75_02845</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56799">
        <property type="protein sequence ID" value="OUO56799"/>
        <property type="gene ID" value="B5F75_02845"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="8"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="357"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO56799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="473" mass="51412" checksum="F439177D5A0951C0" modified="2017-08-30" version="1">MPKNTDFCKIVATIGPDTSNEKAIEQLVLAGVSVFRCNCSHGSLPEYQERVTNIRKMEKKYNCTLGILFDLQGPKLRIGTFKDYRITLKEGDKFRLDMNPEPGDQTRVCLPHKEIFAAMKDGLELLLNDGVVRLRVDAHTADTADCTVIAGGELSNKKGVNVPGVKLPLSALTAKDKEDLKIAEMLGADFIGLSFVQEPEDIIELRSLMKSKAHIIAKIEKPSAIEHLREIIDLTDVIMVARGDLGVETSPELVPVLQKKIVSGCRKAGKPVIVATQMLESMIHNVMPTRAEASDVATAVYDGVDAVMLSAETAQGDHPYEAVATMRRIIETVEKDHRYRKGLSTLERKNDSTKEGAITSAASLVATNMDTANVIVTFTDSGSTTLRASQQRAGGLPILALTPNITTARQLAVVWGVTPIVIENLKNFDDMTAETKKAVLAQKLAKEGDNVVVTAGIPFGKAGTTNMLYVMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGL5</accession>
    <name>A0A1Y4DGL5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56809">
        <property type="protein sequence ID" value="OUO56809"/>
        <property type="gene ID" value="B5F75_02900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="38"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="226" mass="25083" checksum="591B6BC7E6A05E02" modified="2017-08-30" version="1">MPCPLDDISKILIFAFKAAIITLYLTGGYPHEKLLLTLFCLSCFAPFAAAGDWGAAVKLGYGENDPQTMQDLFDYATAYNRELSKSGGIFALEVLHEWPSSEENKIGVKAGLDFYGENELKLHGLGTATEETYAIPVTVYYKWNKGLQNWSYWLGLGLSYLHTELDDLSDSKFFPHITGGVEYRFTQAFALGLDLKYNFSSKITKDGAVLSDRSGLSAALAGRFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH04</accession>
    <name>A0A1Y4DH04_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">B5F75_03690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56959">
        <property type="protein sequence ID" value="OUO56959"/>
        <property type="gene ID" value="B5F75_03690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="338" mass="37377" checksum="9EBE502F939F492B" modified="2017-08-30" version="1">MMLKLLPKTNIDFLKYRKAYYIFFALVLLGGVICFFTKGFNMGIDFTGGTMVQVKFDAPVEMSAIREALSATGTQSELQSFGDHSFAISEKSTSDEVGAVQARIEKALDTLNVPYTVLLTNSVGPAVGENMTERALWSILLSLVFIIIYVAFRFSNILWGVSGVIALFHDLFVMLFAFSLTQREIDLVVVAAFLTVAGFSINDTIVIFDRMRENIHLHPKLKFGELINLSINETLSRTIITTLTVIFAVVVLYLFGGEVINSFAFAMLVGCISGVYSTIALTTPLVYTWSHGEMNDGSNLNKTAAKLSAPVKREEAAAEGYAPKKTVTKIKRTRRNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH42</accession>
    <name>A0A1Y4DH42_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="12" type="ORF">B5F75_06415</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56248">
        <property type="protein sequence ID" value="OUO56248"/>
        <property type="gene ID" value="B5F75_06415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="189" mass="21180" checksum="091C23EE3739829B" modified="2017-08-30" version="1">MANPLIYHKQGWIEVICGCMFSGKTEELIRRVRTALIAKQKVQLFNSKIDTRYGIDSIISHNQNKVAATCVKKSDEILPLVEKDTQVIAIDEINFFDMGIVSVCEKLANAGKRVIVAGLDTDYRAEPFEVTAALLAKAEYVTKNLAVCTKCGNPASFTQRTSKDKKRIVVGTTDAYQARCRRCYKKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHE4</accession>
    <name>A0A1Y4DHE4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsZ</name>
        <name evidence="5" type="synonym">rpsN</name>
        <name evidence="6" type="ORF">B5F75_06910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56338">
        <property type="protein sequence ID" value="OUO56338"/>
        <property type="gene ID" value="B5F75_06910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_B">
        <property type="entry name" value="Ribosomal_S14_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023053">
        <property type="entry name" value="Ribosomal_S14_Z"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="61" mass="7148" checksum="7716AAC78BA2E59C" modified="2017-08-30" version="1">MATKAWVAKMAKDQKFAVRYHNRCQICGRARGYYRDFGLCRICLRKMAHQGLIPGLRKSSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHU5</accession>
    <name>A0A1Y4DHU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56508">
        <property type="protein sequence ID" value="OUO56508"/>
        <property type="gene ID" value="B5F75_04755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="177" mass="19297" checksum="D75519F74154752B" modified="2017-08-30" version="1">MDKIYQKSFFGGKNAGFTLIELLVVVLIIGILAAVAFPQYEKAVMKARVTEAMEILRKMADNVDMCMLANGGSIADCGNTDTVMEGFEGLLKENGVPETKNFTYGWLAAPIAMDKEDNYGLVVISPTINQSGEVDHTTIPSTGRWCMAQTDKGLSFCRNLSNGQSPSTIQGTDYYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHW6</accession>
    <name>A0A1Y4DHW6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polysacc_synt_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00315</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57259">
        <property type="protein sequence ID" value="OUO57259"/>
        <property type="gene ID" value="B5F75_00315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="344"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="482" mass="53260" checksum="44FEE066240EEC8F" modified="2017-08-30" version="1">MANLKRLGKETLIYGTSTVLARLLNFCLVPFYTYYLLPGEYGVIATTFAVVALLNVIFLFGMDQSYLRFASERENKAEVFQHCFYGVLANGAVLSVLLWVFAKPFAGLIGIGAQHMHIIHLAVWVLFLDVLNMIPFTKLRLERRPWYFAGVRTVSIVVNVLGNILFIAWLHKGIASILWANIFGSLASLILLSPVVWGELTKTPFRISRALYQDMLRFAWPFVPAGLASLLISVIDKPILVHLAGLEQVGVYQANFKIGVFMMLLVSMFDQAWRPFFLAHAKEADAKETFAKVLSAFFALGSWFLLGLSLLMPPIIQSDLFGNFHIISPAYWGGLSVIPLVLTGYFFYGLYINFMVGPVLTKKTRILMWITLLGAAVSITTNLSLVPHIGITGAGWAVALSYAAMAGALFCFTQKVYPVAYEYKKLGAMALVCVATAGVSYACSGCSGWTPLGVKILLLTLYPLWMFLILRGQKAAAPSVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI15</accession>
    <name>A0A1Y4DI15_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56588">
        <property type="protein sequence ID" value="OUO56588"/>
        <property type="gene ID" value="B5F75_05185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="219" mass="23959" checksum="C545C48167A0F22A" modified="2017-08-30" version="1">MQALAGLLAVLQKAFLPHLAAGIGLFLMTAYVTYIFLLKPLQWPPVLEAVLVACCFGLYGLVAFSYSLVTACVFALRAACTTWEGFIDDLLGLVKQKVASKIDNMNEGIAKEQAKVVVAGSVQEVAGLFRQYNYASWLRWLAAVLLGVLTFALRSVLLAKIVQISGKTVQLGKLFAGRATLVGAVFLNLRLFSTLLLWVLYAGGVFIVLMNFLFVFWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIA1</accession>
    <name>A0A1Y4DIA1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56668">
        <property type="protein sequence ID" value="OUO56668"/>
        <property type="gene ID" value="B5F75_05610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008822">
        <property type="entry name" value="Endonuclease_RusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036614">
        <property type="entry name" value="RusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05866">
        <property type="entry name" value="RusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103084">
        <property type="entry name" value="SSF103084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="142" mass="16676" checksum="C4FD674696ECEABE" modified="2017-08-30" version="1">MTFPINDGIYRLWVPFRPQAQQRHRFNFKARRAYQPEPEFKACVVAEAVKKRPPRPLEGAVGAKLTYCYRRPACRMYEIYKTTKPDLDNLEKPVFDALKRAGWIKDDANIVHTEIKKIWADFDGLKLELSQLKNVRDFGYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DII9</accession>
    <name>A0A1Y4DII9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methylase_S domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_01530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57479">
        <property type="protein sequence ID" value="OUO57479"/>
        <property type="gene ID" value="B5F75_01530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="254"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="366" mass="42384" checksum="1B63F3C7FBBA539A" modified="2017-08-30" version="1">MALTKYKLGNLIEQRREKYDGEANIQAWGVSCDGFISPKQDSADTSVYNVFYKNDFVFNPARMERNSIALNIFFDKAICSSLYEIFFIKRPDIILPEYLNMFVKRNEFARKCWFEAVGSARNYFRVANLGEFEIDLPSIEIQQKYVDIYKAMVANQKSYEQGLDDLKLVCDAYIEDLRRKMPCEKIGPYIEECHEKNDNNLINLFQGVTVDHIFTDPKRIAEDSENGSIVRTGQFAFNKVMKAHNTKLPIALREGPDCVVSNSYQVFKITNSNKLLPKYLLIWMNRSETQRYAGFMAFGTTRDIFTFQDMQEISIPLPHITVQQNIIDIFSSYQKRSAINEKLKELIKNICPILIKGAMEEGQKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIX1</accession>
    <name>A0A1Y4DIX1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase_M3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_02310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57629">
        <property type="protein sequence ID" value="OUO57629"/>
        <property type="gene ID" value="B5F75_02310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825064" description="Peptidase_M3 domain-containing protein" evidence="8">
        <location>
            <begin position="23"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="9">
        <location>
            <begin position="232"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="682" mass="78158" checksum="3A83EDED4C8B4C9D" modified="2017-08-30" version="1">MKKTKFLLVTAFLLTATGAYCMADMFKNGVLHFDYKAEELAPAEATARVQLEKDLNALVAIPKEQRTFENTIMAYERAFDDYGNALGMSGFLSYVSTDKNFRDAALALQMQISQYMVDVATRRDVYRAIREYTDTNPQLDPVQAKLVKEMLIGFKNSGMELNDEDLEKFKALNKEKAEYIIKFDKNIQEYKDPLAVTREQLQGLGEDYIEKLEKTPDGKYLVTLDYPDYVPFMLNADNEDARKALEFKYNRRGGAENVELLEKTLTLRREIAHLLGYENHAQMKLEDRMAKNPQTVMKFLKNLQKKLKPLAKQEDREMIAYKNGKTGKKSRTLYSWESGYWSNKYRKENLELDSEKIKEYFPSQVVIDGMLDLFGGVFGITFEPVDIPVWHPDVKAFKITDRASGRLIAYFYMDLYPREGKYKHAACFGLVEGEEKKDGTYQIPFVAIVANLNKPSATTPSLLKHSEVETLFHEFGHVLHNALTQAKYSAFSGTNVSWDFVEAPSQMLERWAWDPQVLKKISKHYKTGEPLPDDLIQRMIAAKNFGSGGTYLRQDFFAQYDMTLHTAKTTPDSTKLYFDLTKKIRGLPLTKGTLPQASFGHIMGGYDAGYYGYLWSEVIAEDFFGEFKKNGIFNPETGLKFRREILEKGGTLDEEKMVENFLGRPAKIEPFLQAIGLPQEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ57</accession>
    <name>A0A1Y4DJ57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57699">
        <property type="protein sequence ID" value="OUO57699"/>
        <property type="gene ID" value="B5F75_02685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="107"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="301" mass="33118" checksum="546D64F2AE98E928" modified="2017-08-30" version="1">MKKKTIKRLNYVLLGIIILVGIGLWMRRDPAEKLLGNVPMDVFVVQTEKVQLRDLKRQLLMSGNVKALEEATLYPRVSGKLLKNVLKEGDAVKRNQTVSLIERDEVGAVYEPVVVPSTITGVVGRVYLDPGENVTTTTPVALVVNQSTVRIEVDVPERYIGDLHKGQSAVLRVDALPGKDFEAKLNILSPVVDSMSRAMAVEFVAENPKALLKSGMFAKVDIALAEKKDAPSVSKKSVYTDEQGQTYVYIPSSDKKQAIRQNVKVGFENNDYVEITDGLSTGEEVLAFAYGVKDGSKIEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJL6</accession>
    <name>A0A1Y4DJL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56520">
        <property type="protein sequence ID" value="OUO56520"/>
        <property type="gene ID" value="B5F75_04825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008265">
        <property type="entry name" value="Lipase_GDSL_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01098">
        <property type="entry name" value="LIPASE_GDSL_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="36"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="199" mass="21581" checksum="737FDB8F396447CD" modified="2017-08-30" version="1">MKKWIVLLLAAGAVYYFMKDTPAVKNVNNAGSTVVAFGDSLTAGYGAPKGEAYPDFLSKKIGREVVNLGLSGETAAHAPSRLAHVLEQNPYMVLIEFGANDYMQGRSMETAVAAVGQIVDAVQQAGAIAVIIDTGGPGMGRYTQAYKEMARQKEAVFVPEILKGIFNKRQYKSDMVHPNGAGYEIVAERVYQEIKPYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJW5</accession>
    <name>A0A1Y4DJW5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57218">
        <property type="protein sequence ID" value="OUO57218"/>
        <property type="gene ID" value="B5F75_00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013209348" evidence="3">
        <location>
            <begin position="20"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="177"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="443" mass="48042" checksum="B376AAF341FC5C71" modified="2017-08-30" version="1">MKKILGFLCVLGLTGAAWAAPVQPLSLAACEEAALAFSPAVKAAQAQAQAARASYESVRGNLYPALYLDAAGSWTSEVPQMQVGPQTFEFGSEWGYSAGPTLEYVLFDKGARSAASRRALSLYESKLMEYALARKQALLQVRQAYFAVQRDLENIYLLSEQLKVSRKQRADVHAAYKAGAKSRRDELLAEKQALRTALDASTARTELARDLRDLFKLTGTDFGINPQYPLDWRVREKMEGETSAVIRADAPAQTAKQFAPFQTLTFDAATPRLAAYDGVIQSYEYAARGYAAAVWPRLSLSAGAYAQYPNGPIQEDVFLGKAGLSLRLPLFEGGKNKQQAQAQRLAAQATSVQKEETAQALEALFASAQDSLGALDIEMRLAAQLADKAAQAASLTYQAYQAGAVTFLEVDDANLSALQSRLMVSELLIRRLNGLAVLDSLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJY5</accession>
    <name>A0A1Y4DJY5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckA</name>
        <name evidence="9" type="ORF">B5F75_00200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57238">
        <property type="protein sequence ID" value="OUO57238"/>
        <property type="gene ID" value="B5F75_00200"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="241"/>
            <end position="249"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="447"/>
            <end position="448"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="538" mass="59925" checksum="2931A460AE8024A0" modified="2017-08-30" version="1">MKTLNAKPDFFKPDYGLENAGITTEKTVYWNYSTPALYQQSLSRGESNIVYGGPLCVSTGKHTGRSPNDRYFVETKDIEGKLFYNKSNKGIKPEYFDKIFAKVQEYVKDKDLFVRDAYVGSSEASRLKVRAITECAWTNLFVKNMFIEPKQEELKSFVPQFTLICLPKMKVDPATDGTLSETAILINFEKKMILVIGSEYGGENKKALFTVMNFLLPQKGIMTMHCSANVGDKQDSAIFFGLSGTGKTTLSADITRGLIGDDEHGWDDDGVFNFEGGCYAKVIKLSQEAEPQIYSTTHRFGTVLENVVFDPETGKLNLDDDTLTENTRACYPLNFIENAVESKRATHPKNIIFLTCDAFGVMPPISKLTPDQALYHFISGYTAKVAGTEKGVKEPTSTFSTCFGGPFMPLHPSVYAELLKKKIKAHNVDCWLVNTGWIGGPYGVGHRISIKYTRALLNAALDGKLAKVDFITDPVFGFQIPQSCEGVPSEILNPMNSWANKEEYMVKYESLAKAFIENFKKYEDGCSKEVLAAAPKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK27</accession>
    <name>A0A1Y4DK27_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57278">
        <property type="protein sequence ID" value="OUO57278"/>
        <property type="gene ID" value="B5F75_00425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="1">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="72" mass="8500" checksum="380B45EFA5020D75" modified="2017-08-30" version="1">MKERNLKKLNRLLYLLNRLDGEGINIRREARELEVTERTIQRDLIDIETGGFPLFKAATGVYKFIEGFFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK35</accession>
    <name>A0A1Y4DK35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57288">
        <property type="protein sequence ID" value="OUO57288"/>
        <property type="gene ID" value="B5F75_00475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="145"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="375" mass="41147" checksum="C14FA7B82EFD8619" modified="2017-08-30" version="1">MMIFFLASVLFLLLVLAANLFIKRAPQARAVLLAAAASLALVSLAGLLFVRWSGGHAEFLRPWAFLFLLVPFAVLMAQTVFRGAFTRRIAYPMTHLKVEQASLRVLFTKWLPLGLYTLSLLFMTVALARPVRVDRTVLPPTEGIDIILLMDVSASMQKQDFYPNRFIAAQQTASRFISKRFNDRIGLVVFAKEAMLQAPLTLDHEALQEYLSTLYLGIVDPNYTAIGDALGVAANHLKDSKAKSKVIILLTDGDSNAGTIAPQMAAKAAAAYGIRVYTIGTASAPGESLYSSAEDEINEGLLMEIANTTGGKFYRAKNEAELTQIYDTINELEKTEFAPSSTVNRSDAYQPFLLLALACAFAAFVLEKVFFIKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKC5</accession>
    <name>A0A1Y4DKC5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57378">
        <property type="protein sequence ID" value="OUO57378"/>
        <property type="gene ID" value="B5F75_00985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="177" mass="19451" checksum="310BFCA1CCA825BE" modified="2017-08-30" version="1">MNKHGFTLTELLVVVVIIGILAAIAVPWYQTAVDASRYTQLQVVVKSVKDGVELARMMTGSYPDSLEDLDIELPAGCTLQTDKTVAQCGKFYIDYLDGDDENIVGMMNFDTNTFTPSGNYVAYVMWLDYAANQAGRRECRAGASSSRMQKLCEDQPGTPDGTAGGSYCPSCKRYWLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKH7</accession>
    <name>A0A1Y4DKH7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_01255</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57428">
        <property type="protein sequence ID" value="OUO57428"/>
        <property type="gene ID" value="B5F75_01255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013322875" description="Non-specific serine/threonine protein kinase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="124"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="234"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="498" mass="56667" checksum="9C5112F1B61C769A" modified="2017-08-30" version="1">MLMFKKGILLLVGVLLWGAALWAAPATQNAPLIVGGNFSSQTNTSVQTKVFNQQARNTEIASLNKQLKERRFNEVIRRINELTAKNFLDNRFHLLLAIAYDGLGRYDDVIYSAGQAIAVAPQDSRAYILRGGAYLHLKDYERARIDVETALKLNPSSRLAQKLQDELNAKTSAVKTTADPAQKAVKKSTPRWIVLYFVAVFIAVLLFVYWRYEDVFRQPRNAFSRREVEVKEQYDFIRQIGEGGMGKVYEAYDKVLKRKVAIKRVRPELVRSSYVREQFLSEARMVALLRHPCIVEIYTVIESESSLYLVFEYVDGQTLETRLDIDGRLPFSKAKRIFEYVCRGLQYAHSQDIIHCDLKPGNIMIFDDDKAKVMDFGVAKKSVDHETGARTVAGTPAYMAPEQQKGFMRKQSDVYSLALCLYEALVGQVPWTVKGFDIAKKKIVPASKLAPNIPPAVDGLLEDALKEDPKERIQTIDEFWSRLKAIDPLPEDLERTHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKJ4</accession>
    <name>A0A1Y4DKJ4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PgpA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56820">
        <property type="protein sequence ID" value="OUO56820"/>
        <property type="gene ID" value="B5F75_02960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008962">
        <property type="term" value="F:phosphatidylglycerophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06971">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026037">
        <property type="entry name" value="PgpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036681">
        <property type="entry name" value="PgpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007686">
        <property type="entry name" value="YutG/PgpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36305">
        <property type="entry name" value="PTHR36305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04608">
        <property type="entry name" value="PgpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101307">
        <property type="entry name" value="SSF101307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="PgpA" evidence="2">
        <location>
            <begin position="30"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="162" mass="18259" checksum="6102D8ABDA496E26" modified="2017-08-30" version="1">MQVIIRALATGLFVSYLPPLVFKYKKNTGAGFLGTLWGVALVLVFPRDAMLYLIAMLAFWVFAVIICKKVQFKGYTGHDNPKIVIDEMAGYITAMAFLPRTWPYLAAAFVLFRTFDTLKPWLVKTFDRMENAFGVVFDDVAGGLMANILIQLFIIFFVKGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKQ2</accession>
    <name>A0A1Y4DKQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000006">
        <property type="protein sequence ID" value="OUO56001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56001">
        <property type="protein sequence ID" value="OUO56001"/>
        <property type="gene ID" value="B5F75_07225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="415" mass="45089" checksum="FA2373ACFC52CAD1" modified="2017-08-30" version="1" fragment="single">MFVVTGYYTTSLSIDVSEDDISNRSFAFGIDPTSNSTTNDPWVSSALIEYDQPYPAVTPSTNKYPNHCLALCMNVYCTNKPMAQSTYSIAFPLQQVKFDIVKYYNGKNVENPEETPAIRTIDLYPDTESDSAICGSYRCPGGPDSGYTCSSPDYEERNGTCYQFGTNTTSSSCSCDSGNKTCNYVIFNNDGTPSNQPIPFCAAWDGSYEIAGEFGKSNGDFAFRATVSTDFPGDNIITDKIEFSSTIAYPGMNQIPMQVDVTNVHTVRSTPTVVGNITAVSAQPYTFAYRLSKDADVRVAIFDASNGDNINYGGTNNGNITAPSGNSNGALVRTLVDWQPRIGEGMKGVDKDTQITEFDSWDGRNDNGLLLPAGNYITAIQAKAQDEWPGVDFSRAVTRQMSLDPLKLTDIVATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKX2</accession>
    <name>A0A1Y4DKX2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GP-PDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57578">
        <property type="protein sequence ID" value="OUO57578"/>
        <property type="gene ID" value="B5F75_02045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="234" mass="26341" checksum="235938DE64617470" modified="2017-08-30" version="1">MIYFAHRGASARRVQNTLEAFRLARRLGASCYELDVHLTQDGQLVVHHDYSLLATAGKDAKIGELPWAQLRRCALQNRFDGAPAFIPLLQEVLPVVAPGLELLNIELKNDANCYPGLEEKLLKLLAGEYAELLSKTLFSSFDYDTLLRIRKLNKNARIGLLTRSFDVSKALDLQAESVHLNYTRFSPATAEECHQNGLKTYLYTVNDISLAKRLQQEGADGIFTDYIDLFVSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL83</accession>
    <name>A0A1Y4DL83_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57060">
        <property type="protein sequence ID" value="OUO57060"/>
        <property type="gene ID" value="B5F75_04220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="89" mass="9842" checksum="C2150EB138410E1B" modified="2017-08-30" version="1">MRVEIKKIGISTVLFSVFPLAVFVVMMLSALMEVFNPDAVINAAYIMGLVMRAIQSTLLFLVSAVFFLLAYNLLCAVGIRGVRVELEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL91</accession>
    <name>A0A1Y4DL91_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57698">
        <property type="protein sequence ID" value="OUO57698"/>
        <property type="gene ID" value="B5F75_02680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012079407" evidence="2">
        <location>
            <begin position="21"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="459" mass="51295" checksum="4E971E5C175DE68A" modified="2017-08-30" version="1">MRKWIVLALLAMYAPVGLEAAPNNSANSLFAEREEVGGEKITIADAIRMALSDSYQIIDAQKTKEIYEEQLAEANSYFYPSLSLDGSYSRALKKGKIIMGSNSIEIGQNNTYTAGLSGSYILWSGGQIRNTARAAKVGAETGFYNLRHVQDLVTQQVVKFCYDIIYAAALIRVQEEYLDIAKQHLAEAQAKYKQGLASNLDVLTQKVKVENIEPLVLQAKKNFELGNLYLRQILNRDPEDNIYLTWSEKDLHLPPTPPLDELYRIAMERRPELMLSKLAVDAAHYNINIAKAGHMPVLALNADYTYNGITDHGFPQHKQDYYWSSSAGVSLSIPLFEGGKVSSQVAQKELAYEQAVAAYQNKMKNVRIEVKEAWLNLEEARSRIEATKGVVDEARENLSAQMQRYRAGLTSQLEVNDAISNVNDSDLQFVQAVYDGAIALSDLKFAVGAEVELYEKKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLQ2</accession>
    <name>A0A1Y4DLQ2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="10" type="ORF">B5F75_06875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56331">
        <property type="protein sequence ID" value="OUO56331"/>
        <property type="gene ID" value="B5F75_06875"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADK_lid" evidence="9">
        <location>
            <begin position="145"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="50"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="103"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="233" mass="25671" checksum="443A7223E601C3C7" modified="2017-08-30" version="1">MIFAFRSAGLNAVLFVKDLKVNIVLMGCPGAGKGTQSAKLQDVFHLKHISTGDVLRAEIASGSALGKEIAGIINKGNLVPDELMISILEKIVKATDKGIIFDGFPRTVAQAKALDEMMKRLQREITEVVMIELPESEVVSRIASRRQCRKCGEILHVAPDAPASSACPVCGGELYTRPDDTPERVKHRLEVYHTETLPVKNFYQNSGKYVEINGNQTPEQVFEDIVRVLKKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLZ4</accession>
    <name>A0A1Y4DLZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56421">
        <property type="protein sequence ID" value="OUO56421"/>
        <property type="gene ID" value="B5F75_04295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="283" mass="31275" checksum="FDC8CE3A95880E27" modified="2017-08-30" version="1">MKKLVLFDLDGTLVNAGGAGRTALKKAMKELYGTDPEFDHSLISGRTDLDNFSIVYSLIKKGKKPTAAEMKKMKAKYLELLPVEVHAAVRCKRYDLIPGVEKFLKLLSKDKDVILGLGTGNLEEGAKIKLAPSKLGEYFSVGGYGEDGHTREEMLQAAVKRAEKKFKTKIAPEDVYVIGDTHRDVCAAKNCGFHSAVLTNGFGDAQKIQRAAAELETKDFTDITTFCVWLGIKTDPKGVKRGSYIMPASAIEHVFFSRTGIDEDRLKMLRIKKYSDLESGTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM19</accession>
    <name>A0A1Y4DM19_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ion_trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_04405</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56441">
        <property type="protein sequence ID" value="OUO56441"/>
        <property type="gene ID" value="B5F75_04405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="214"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="28"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="255" mass="29016" checksum="0DAB74EDE65ECB21" modified="2017-08-30" version="1">MTKTIPSAKRYLYDILQFNNRSKVTTALNALIITLILLSVPVDVLESVQDVSPAVKRIIYHVDLVMSLIFALEYALRLITCTEDPRFSRPIVGRLEYMCTPLMLIDLFAISPFFILGTGMVRMLRVFRILMLMRYTNAIQLVNNVVSEKKSELSICGAFLLMLWVWSAFMIFRVEHAAQPEVFRNMLDAMWWSAETFTTLGYGDIVPITLFGRIITVITVAMGLVLFAITTAVLTAGIVQEIQKFEHKKQQPPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMA1</accession>
    <name>A0A1Y4DMA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57420">
        <property type="protein sequence ID" value="OUO57420"/>
        <property type="gene ID" value="B5F75_01210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012160">
        <property type="entry name" value="LtaS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005091">
        <property type="entry name" value="Mmb_sulf_HI1246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="283"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="514"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005091-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="673" mass="77298" checksum="8E7F9AC83B8A6F48" modified="2017-08-30" version="1">MKKIVLPGWIKAYFGFILANWLLFTLMRGIFLFVFRAALVPQSYPELWETFYVGAKFDMRLACALAIPLGLYFTVCAFWHKARAIRKGMAWLYGVLEAVVLLVYFLDFAHYSYISMRINYSILKYAENPLISLQMAWETYPVVWGLLGLALWGVLGGWFANYVQKKAFAQTDSYRWKGNLGWFFGGLLLTGALMFGQLSQYPLRWSNAYHSTNNFICNLTLNPVLNIYDTARFVKADSYDEEKTRRYYDAVSKYLQVDQPNKETLNFERVIAGKPAAERKDYNVVVIFMESLAWNKLSMTNPDIDPTPFVKELSERSILFNNFFAPTSATARAVFATVTGIPDVTSFKTSSRNPLIVDQHVVVNALRDYEKYFFIGGSASWGNIRGILEHNLTDVHMYEEGHFKNEHRNDVWGISDLDLFREANRILDEEQKAKKKPFFAIIQTAGYHRPYTIPDDNAGFEPKDIGEELAHKRSFVSVAEYNSLRFSDHALREFFKLAEKSDYYDNTVFFIFGDHGLSAPQSENMPRGYVDLNLINHQIPLIIAGKPIEKPQVISRTASQVDILPIAMGLLGRPYFTRAIGRDVLTDSEAEPGSLIYGWASTPATIGFVQGEYYYHNSGGKEGLYKFTADNYNEDISKKDPARFEHMKNLALGLYETSRYQFYHNQKRDERDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMI1</accession>
    <name>A0A1Y4DMI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56601">
        <property type="protein sequence ID" value="OUO56601"/>
        <property type="gene ID" value="B5F75_05260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="7"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="337" mass="37772" checksum="687B9437A0C54210" modified="2017-08-30" version="1">MSEKTVLVTGGAGFIGSNFIPYFLEHFPPYRVVNLDKLTYAGSLENLKECQNRARYTFVQGDICEAELVNKLFEQYDIRGVFHLAAESHVDNSISGPLPFVKTNIEGTFTLLEAARLHWMQAPGQVKPGYEGCRFHHISTDEVYGSLGETGYFTEQTPYAPNSPYSASKASSDFLVRAYYHTYGLNVTTSNCSNNYGPKQHAEKLIPTIIRRALGGQPIPIYGDGKNVRDWLYVLDHCKAIVRVWQKGRAGETYNIGGHNERNNLQIAAAVCGLLDQLKPSAGGKSYQAQITFVKDRAGHDRRYAIDASKIETQLGWKPEENFATGLRKTVEWYLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQE4</accession>
    <name>A0A1Y4DQE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57591">
        <property type="protein sequence ID" value="OUO57591"/>
        <property type="gene ID" value="B5F75_02110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012892802" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="719"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="786"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="862"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="902"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1207"/>
            <end position="1225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1268" mass="134787" checksum="BF13EBE4BEB4517A" modified="2017-08-30" version="1">MNKILAAILSISLLVSSVTPSLAQLVPAGRQVVKGLTQSGAKSAAVTAGKALPGKLVQKGVSAAAAHAAAVPVSSAAKSAFPSVSVASPLPSYDVSQLRLNVDRSVRQQLTVSGKEIRALVAAGQTDGLASRILSYPKPSFREGLLRNEFVTVALKGGADKAQVAQAVQFYRTDLANNGGAFAQLPQADLNTLLKIARTPEHPSYQIVSQSQQALSSAAALGLLGGAEDGASLLAFYKQASSSVFKDAAQRIAARGLLRQGAYKELQELAALVKAQGPFWKDVAARAHEKGVQISVADGAVAPSAEDDALAVFLRAGCQPNALNAKASSEATDKWLSLGTPAETASAQKAAAPEPMAALDISLPQVALPAADLNVSPITLPGGTAAAEQPAPAPTQVQQKTVQFFAKSTPSSSSGTLYSGLPVFEAGKLFKKAASWLRGKWGKKEPALPSAPHEEPGLHDDSEIHEVFSNLRSPEAPASADEVMGANETGFIPVSEKGFKLTLVDEQGVEKILPVNLEISNRFRVKGYNRIAFAAHSDFKHGYVAELRNQEQEPLRMAHFYMRLQRNQVGALADLIQATGIEKFNLKLESTPDVVYKSVKLPVYDFLSGKELPLEVEMPVKAYVENAKMVVMENGALGLLKPGATQPTALKGFYVRLPKNQIANFVEVLRFSPTSFNVSVHPTRNRADLIMRDASLTNVSLGKTMGPMVNGSLGMEVSAANSMMFTINYILPGLASLLTPVLKKYGEKKLMVLSLAMSSAAGVLASAGGFYGFVEGLTLGPVSKGLFITALFLMSGSSILKQLVSNMLIRANRGEVILNDAKEAVKASETEFTAEQKHGFAQMGLRLKEFFTKKSEVSLKDVVLYNLSFVYKNVGTLAFLASPYLINHGILLATGVDLGIDYSISFPIYAVYSGVVAWKVWRAKLRDAYSAKNLEQSKKNLELALHSGAKALAGVKGKISSTQIDDAARAFKDALDALVFADVKLNPGQKKADLYAKEKKNFLQKLENKLSNEYAMDPARVKEITGQIKHSLAVQENTLGNILKMLKAPGVLALSSAMTLATVHEFVISSSFASVMKQLINQGELANFLIACSLYVPLIAGRLGGNIISRRISADSMYIFCSALSALGTLVMATAGDSVAQMITGAAVASFGVGNFFTQMYDYIMNKYPKQNRELSSILALTMALGGLGAIPAGYLASMTGFDASSLLYAGAALGASLVLTPGMTKNSTIVKELKYEAKRLWKGVKKLFKRGGKNPPAGNLDDAAPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQL2</accession>
    <name>A0A1Y4DQL2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-glyceromanno-heptose 6-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_02485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57661">
        <property type="protein sequence ID" value="OUO57661"/>
        <property type="gene ID" value="B5F75_02485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008712">
        <property type="term" value="F:ADP-glyceromanno-heptose 6-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011912">
        <property type="entry name" value="Heptose_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02197">
        <property type="entry name" value="heptose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="312" mass="35076" checksum="A48B51FBD3815275" modified="2017-08-30" version="1">MDAKTKKKYLVTGGAGFIGSNIAKTLEAQGHEVTVMDDFSKNGHFKNLIGFKGDVITADLFEYMPTDMYFDAIFHEAAITDTTVMDQKAMMEQNVEAFKNLLNFAAENEIKKVIYASSAATYGNGPVPNVETQPTHPENVYGFSKVIMDNVARQFAEDNNDMTIIGLRYFNVYGPGEYYKGKMASMVYQLYNQMKAGKRPRVFKYGEQQRDFVYVKDIVKINLCALNNGKETCVYNAATGIPRDYNAIIACLNKELGTNLEPEYIDNPYPFFQLKTQADMTLAKEKLGYEPDYSLEAGIADYVSILEGRNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9Y7</accession>
    <name>A0A1Y4D9Y7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elongation factor Tu</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_07010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56023">
        <property type="protein sequence ID" value="OUO56023"/>
        <property type="gene ID" value="B5F75_07010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP_EFTU_D3" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="35" mass="3721" checksum="446BB00B7C1DBF22" modified="2017-08-30" version="1" fragment="single">EVKLITPVAMEEGLRFAIREGGHTVGAGVVTKIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA22</accession>
    <name>A0A1Y4DA22_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_05665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56107">
        <property type="protein sequence ID" value="OUO56107"/>
        <property type="gene ID" value="B5F75_05665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="73"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="334"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="403" mass="45809" checksum="DAACA47F9AF896BB" modified="2017-08-30" version="1">MLYMENESLDSVNEYFKHLGKITQEIDREEMARLWKRAKKGDKDAKNKIMEMNLRLVIPTAKRFQRPGMELMDLIEEGNLGLMQAIDKFEPEKGYRFSTYAVYWIEQYIRKYIEEQSGSIKIPSHAWGNLKRWFRAWNELKEANGRDPSLNEMAAELNLTARQVKSIMDTLSAAKGVDSLTTLVHEEDETTLEDLISDDGKGNPHDVFLKNENQDTIKKSMEELNDRDRQVVIMRYGLADNEPKTLGEVAEILGLSRERVRQIEERAVNTLRKEAQKAGILEVSPVDLRTRKLHSAMRPRLKTNILGETQDNSPLARLLKKRAALVAQAKADKKKAKQAASKKAASAPASKKTASKKHSAVSQQNKKTAAKKTAKTVLKKAKPAARKTQKTARKTASRKTRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA33</accession>
    <name>A0A1Y4DA33_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">B5F75_05715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56117">
        <property type="protein sequence ID" value="OUO56117"/>
        <property type="gene ID" value="B5F75_05715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="19738" checksum="224B7D9D7E0DDC6C" modified="2017-08-30" version="1">MAILRVTKYGENILRQKLKPVDFKTLEPLLPKLLKDMEETCLAVRGVGLAANQIGLEYRMAVILIPQSAEENAPLTRYVIINPEILSMRGEKLEEEGCLSLPGLWAEVKRATDVTIKYTDEHGQEQVKRARGLLAKAFQHEVDHLDGKLFIDLVDPALKPEVKKAIKKLRKNWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA35</accession>
    <name>A0A1Y4DA35_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56114">
        <property type="protein sequence ID" value="OUO56114"/>
        <property type="gene ID" value="B5F75_05700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="145" mass="16413" checksum="99080D1BC97D247B" modified="2017-08-30" version="1">MDNIVILQLIGFTVCFILLFVFTAKYRAALAHETDFEPAVEDLTVVTVAQPPAFKPRASILQSLQGSASLEVADLKEKVKDLHYRLEELKVAHDKSNAEISKQLSRLEQRLGTFEQEYVTKLQPTLISLIEELENMKVAEDKPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA95</accession>
    <name>A0A1Y4DA95_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase T</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_05995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56167">
        <property type="protein sequence ID" value="OUO56167"/>
        <property type="gene ID" value="B5F75_05995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010992437" evidence="7">
        <location>
            <begin position="23"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="451" mass="49300" checksum="A505A37792029F28" modified="2017-08-30" version="1">MNKYVKTALLAAVCFLPLAAAAQEMDWKSVTRYNKAEAKKQLTERFTKYVTFDTQSSDQTDKVPSTEGQTKFAKTLVKELKKNGAKNVKMDKNGIVTADIPANSDRNAPTVAFLAHMDTALEVSGKDVIPQVHANYQGGDIVINAPRKLVLNAANSPQLARARGHDIVTASGGTLLGADDKTGIAVIMTMVQYLYDHPQMQHGPLKIAFTPDEETGAGVARFDVASFGADYAYTLDGMDTGALTNETFNAKAFTAVFEGMRSVHPGEAMNSAFSDNVLMASDFHTLLPRHRRPETTSGRRGFILVDSITTQGDKTEVKGIIRAFTDEEMQDLVNEVTRAFNTVKGMNYKGKGFSLTFTDQYKNMKQALPEQVVSLAQLAMQNEDITPVLTAARGGTDGSALSFMGLPTPDLFAGQFNVHSEYEYADVDVMEASLRTVLRLISLWHMQQPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAG2</accession>
    <name>A0A1Y4DAG2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02715</name>
        <name evidence="2" type="ORF">B5F75_07220</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="journal article" date="2018" name="BMC Genomics" volume="19" first="0" last="561">
            <title>Whole genome sequencing and function prediction of 133 gut anaerobes isolated from chicken caecum in pure cultures.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
            <dbReference type="PubMed" id="30064352"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56056">
        <property type="protein sequence ID" value="OUO56056"/>
        <property type="gene ID" value="B5F75_07220"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57719">
        <property type="protein sequence ID" value="OUO57719"/>
        <property type="gene ID" value="B5F75_02715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="36" mass="3904" checksum="DFEFA4043347947C" modified="2017-08-30" version="1" fragment="single">MAKEKFSRSKPHVNVGTIGHVDHGKTTLTTAITKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAS8</accession>
    <name>A0A1Y4DAS8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_06730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56304">
        <property type="protein sequence ID" value="OUO56304"/>
        <property type="gene ID" value="B5F75_06730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_3" evidence="5">
        <location>
            <begin position="30"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="194"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="416" mass="46193" checksum="484BDCCE66A083A0" modified="2017-08-30" version="1">MPAVCGGAAVFKTGRNGKITDRGIYRMIEIKLKAKEERRLQAGHWWVFSNEIDGLDTSVEPGTLVRVLNHEGKQVGIGYFNPHSLISVRLLMKGEGELPEDFVFENLDNAYSYRKEIGVRKYGRMCYGEADNMPGLVIDRYGDVLVIDVLTAGMEKLKPAITKAVQKIFKPKGIYYKNDSSFRALEGLTNTPEIIGDVPETVEIEENKVKYLVPLRGGQKTGFYFDQRENREFLKPYFKDKLVLDLYCYIGSFGITAALAGASQVWGCDSSAAAVECAQKNAALNGVSDSVVFHRDDAERLLSALKKGELPDQPDIVLLDPPAFVKSRKALPQAVGLYVKLVKMALEGIKAGGYLAFSTCSHHISRELFVDIIRQGVSKSGRKAVLVELRGQAKDHPVLIGMPETEYLHFALVQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAT1</accession>
    <name>A0A1Y4DAT1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56156">
        <property type="protein sequence ID" value="OUO56156"/>
        <property type="gene ID" value="B5F75_05935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="166" mass="19314" checksum="FCF9E011492CBB03" modified="2017-08-30" version="1">MTSFEALYNQYFKPVYAYVVTRINDPAAAEDICAGTWKKCYEHLASYDEAKGTFSQWIFTIARNETNMYRRLFWVKHFFSLAQTPDDLLPGKEKSPLEQLEQDSLQRQLLAAMATLSEKERDLLSLKFYSGLTNREIAAVTRLSESNVGTMLYRAVQKIRRYMEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAV2</accession>
    <name>A0A1Y4DAV2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">B5F75_06885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56333">
        <property type="protein sequence ID" value="OUO56333"/>
        <property type="gene ID" value="B5F75_06885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="29"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="16342" checksum="DC76C4170CE13AA1" modified="2017-08-30" version="1">MVTLNKLFPKHGSRKEKRRLGLGPGSGLGNYCTKGMKGQTSRSGNTRKESKEGGQMPLIRHTPKSGFSNKDFARRYDYVNVGSLEKVFAAGAEVTPEALKKAGIIHDVTRVKVLANGSLTKALKVSAHGFSATAKAAIEKAGGTVTVLEQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAY4</accession>
    <name>A0A1Y4DAY4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56363">
        <property type="protein sequence ID" value="OUO56363"/>
        <property type="gene ID" value="B5F75_06775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="100"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="246" mass="28628" checksum="CEBCFD5F12F5C3FD" modified="2017-08-30" version="1">MVHRTPPKVYVHCIKFNRFLYNIYMADTQSVISDVKLFIERLKKELPEVFGQPDAKPGAASVQTPSDTDNKVLYNGDLFEARMYVTPDQEEGVAFDGTIFHIYLHSKDSDPSALVTEWLRNKANETLKAKTKEWAEKIGVEFNNIVIKDQKTCWASCSGKKNINYSYRIIKMPLAVQDYLMVHELCHLVHMNHGQEYWQLVAQFSPDYKSHRRWLNENKGSIFAEVELTYREEPQEDARLKDETTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAZ3</accession>
    <name>A0A1Y4DAZ3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">B5F75_06980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56364">
        <property type="protein sequence ID" value="OUO56364"/>
        <property type="gene ID" value="B5F75_06980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="18"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="13015" checksum="D701BAF46DB90676" modified="2017-08-30" version="1">MAEKTEKRAHVLSQERIRIKLRSYDHRMLDASVSRIVETAQKTGAIVAGPVLLPVRIKKYTVLRSPHTDKKSREQFEMRIHKRLIDLKSPTSKTVDELMKLDLPAGVDVAIKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB36</accession>
    <name>A0A1Y4DB36_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ORF">B5F75_07025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56025">
        <property type="protein sequence ID" value="OUO56025"/>
        <property type="gene ID" value="B5F75_07025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="62" mass="6710" checksum="4BD5E1B2CD158815" modified="2017-08-30" version="1">MNKAIDFLKQSVGELKKSTWLSRQEVVQSTILVAIVVALVSAYVSVIDFGLTKVLGFVVGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBA0</accession>
    <name>A0A1Y4DBA0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyruvoyl-dependent arginine decarboxylase AaxB</fullName>
            <ecNumber evidence="4">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_04415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvoyl-dependent arginine decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56443">
        <property type="protein sequence ID" value="OUO56443"/>
        <property type="gene ID" value="B5F75_04415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016104">
        <property type="entry name" value="Pyr-dep_his/arg-deCO2ase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016105">
        <property type="entry name" value="Pyr-dep_his/arg-deCO2ase_sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002724">
        <property type="entry name" value="Pyruvoyl-dep_arg_deCO2ase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40438">
        <property type="entry name" value="PTHR40438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01862">
        <property type="entry name" value="PvlArgDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01170">
        <property type="entry name" value="Pyruvoyl-dependent_arginine_de"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56271">
        <property type="entry name" value="SSF56271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="203" mass="22546" checksum="044E5A2B6603E910" modified="2017-08-30" version="1">MEKELVLGTRYPTLAFISGGAGQAADGIPPQPFETFCYDSALQQAKIQDFNVIPYTSVLPKDLYRNIYPVDAVADQFTHGAVLEVIMAGNGARIEDHKAIATGVGVCWGKDKKGNLVGGWAAEYVEYFDTPIDDEIASGHAHMWLNKSLNHELEIRGVEKHSEFQIWHNYINITQPFAYCLTVMGFLNFKFAPVAVPHQKALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBG1</accession>
    <name>A0A1Y4DBG1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56504">
        <property type="protein sequence ID" value="OUO56504"/>
        <property type="gene ID" value="B5F75_04735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="432" mass="50384" checksum="430956916300B138" modified="2017-08-30" version="1">MSSHYPACQQAGFLFFINSFAAFGANLYNLSMSLKHWIYSFRPLCVAYETLRWLWHKIFFFIHTPTPVWYQFDRKHQPVASVKETLPMDKNWYRICRPLYRHEHVYYDLQKALAANPNVKGVALIFFMGIGDYLYTTPMLAALKQKFPRLPFYAYVGAQFDRNNSPLVGKLLAENPNFEKVFYFNGTRHPLIWKNYDYSDAFKDIPEGFLAVPVYYDYGVHVGHRVTNLFETFSLPVPERVPAPVMYFAKDIAPAVADYLARARRGAQGKKGIVFLQLDSRGSNYAYPHMKALAQGLIQEGYFVMSVTKGGPTDNPDYLEIDIKKLAINQTWQFLSILKGEFPLYVIAVNSVFWAASAGMQLPNLGLQHWIDKKVHNLWYPNIEVVTNYIYPHLPREKQLFAPPESYTRHNKKIIDYKPDWVIKWFKEKFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBK5</accession>
    <name>A0A1Y4DBK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56446">
        <property type="protein sequence ID" value="OUO56446"/>
        <property type="gene ID" value="B5F75_04435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="440" mass="49739" checksum="AFA17C881D76652C" modified="2017-08-30" version="1">MFYIICLLVGMAIGSGAAWAALAGKIKWLTAEQQRLLALEPELNRLRAENAALQVEKTRLEQEKVSLEKEKTLIEKNFKELSGTYQAQFAQLASKILDDKTKGLEAKNSEALRPLTLHLESFVKKVAEMERQNTAVQARLEKGLSDVIKSTEKIDQSALHLTNAIKGEAIVRGSWGEETLKRILDAAGMKEGLDYYQQVSEEGKRVDVQIALPADRWIVVDSKTIFNHYARYFNAQDPKEKETFLNEHVKDVKKTIKDLSSKKYYKKFQAEGDKVQPDYTLMFVYPESALLAAVEADPDILNEAWKNNIALVSATSLMSTLKMVSKLWDIDKQHEYMEDFKEDILKLLEKFNDFLVNFAKAENAVSAAADAVKIARGHIDGNRGAFLPVAQRIVDIYEVPLTKENARLLKRMNYDYTGHKSKNHPAAKEIPPADEKGLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBM0</accession>
    <name>A0A1Y4DBM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_04540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56466">
        <property type="protein sequence ID" value="OUO56466"/>
        <property type="gene ID" value="B5F75_04540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="466" mass="50656" checksum="F70C24431282AE3A" modified="2017-08-30" version="1">MAQAVSIQTHNPFKARTISQLLIKFSAPAVAGMFVNAIYNIISRIYVGQDVGANGLAGITILFPLGLIYMGFSALIGVGANALFSIRLGEKKEEEAQMILGNAFVLLALISGIITLGSYFFLDSFLGFLGADSEVLPYARDYAKVVLPGYFLFGISIGLNNFIRSSGHPKTAMATQFIGALINIVLGPIYIFVFDWGIQGAAAATVSGQAVSFIWVMLFFTGQRSFYKLHWKFFRLKAYIALDSMAIGFSQFAFQLASSTLNVILNHSLLKYGGNLAISAVGIAVSVNTLVMMPLIGLSQGAQPLIGYNYGARKYATAIQTLKMAMRWGMGITTAGFILLEIFARPIASVFNSDNMALVDLSAQVIRLFNLLLPIVPLQVLTTSFFQAINKPLKAAFLSLSRQVLLVIPLVLILPLFWGLTGVFLAPVFADAISVTLSVIMIKNFFDKHGQNFFFSKKHSPARKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP0</accession>
    <name>A0A1Y4DBP0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dxs</name>
        <name evidence="12" type="ORF">B5F75_05105</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56573">
        <property type="protein sequence ID" value="OUO56573"/>
        <property type="gene ID" value="B5F75_05105"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="618" mass="67412" checksum="24C51B9DAC1338A1" modified="2017-08-30" version="1">MKVLPSIQSPKDLRLIKKELLPTLCEELRSVIIDTASKNGGHLGSSLGAVEIITALHYVFNTPEDKIVFDTGHQAYAHKLLTGRQKEFHTIRTQKGLSGFPKRCESPYDTFGVGHASTAISAALGMAIARDQKKEKNKVIAVVGDGCLTGGMAYEAMQNAGLLRSDLLVILNDNQMFISKRVGALGKALTKLLTTKYVQLAEEKASNFLKRFDELGNNAAKLAKRARSILFPGTLFEEMGFRYFGPVNGNDINEMIEVLESVKDVKGPVMLHVVTKKGKGYKPAEEKPTKFHGVGVFDVDTGDTIGKSNCITFTQAFSNTLVKLAEKDPSITAITAAMPEGTGLDAFRDKFPSRYFDVGIAEEHAATFAAGLAAGGMKPVVAIYSTFIQRCYDQIIHDVALQKLPVVFALDRAGLVGEDGPTHHGVFDLSFLREVPNLIVAAPADENELQHLLKTALDAKAPFVLRYPRGSGFGVEMDAAPKRLEIGKGVWLKKGKDLNILAIGNRVHPAMQAAALLAEKDIDCGVANMRFVHPLDTHLIDEALKLSRRIVTVEDNMLAGGFGSAVAEYVSDKQADFKLLRLGIGDEFVEHGKVAQLYDQLGLNAEEMTKHILKWKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBT4</accession>
    <name>A0A1Y4DBT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56526">
        <property type="protein sequence ID" value="OUO56526"/>
        <property type="gene ID" value="B5F75_04855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="80"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="202" mass="22783" checksum="5C8507E1CE9A3484" modified="2017-08-30" version="1">MKALHPKQAELLEILKANISDPLTMEELADRLNLSAKSVVFHHIKQLEKKGYLKRNPANPRDYIILKDPEKNVIYLKMYGMAKCGPEGTLLDGTPTRIVPVDPSMIYFPACKGFMVEAKGDSMQTLIAPHDWLIVEQNHSPKNKDVVVCVNNGEVMVKRFTKDGENVILQSENPQYNPIIADRDSFHVEGIVRSIIKRSVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBZ4</accession>
    <name>A0A1Y4DBZ4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56576">
        <property type="protein sequence ID" value="OUO56576"/>
        <property type="gene ID" value="B5F75_05120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="15605" checksum="44C2E34B8AC859C3" modified="2017-08-30" version="1">MIALASLVFSLIAPGAGHILQGYYAEGIIIGVLFGFGKSVLLPLVLRVFRVTTLKRTLQLLYLFNWGYILLILYAALSSFWRGFSATQMHFWYALLFAIAVTLSYKKTLNAFIFTALCGRTEIYPLVRAKRKNTTEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC34</accession>
    <name>A0A1Y4DC34_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SpoIID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_05340</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56616">
        <property type="protein sequence ID" value="OUO56616"/>
        <property type="gene ID" value="B5F75_05340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02669">
        <property type="entry name" value="SpoIID_LytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012486424" description="SpoIID domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="SpoIID" evidence="3">
        <location>
            <begin position="154"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="417" mass="45932" checksum="89DFC8AE31704358" modified="2017-08-30" version="1">MKHLLRFQLLFLATLFISACAVPSQRAAVGAQAAKESQINSSALTRAPEPKSQDPQAKRRPKDLTVRILLAEKQKSALIKHTGKVYIYTLNLDKKYKISAPGTLSVKALGSGKIQVGTLQANKTIVLEPALNTLLVWNKNSYSGKIFIIPAGNTFHLVEHAPLETYLYGVLPYEMSHSWPLEALKAQAVAARTYTLKTLENVKNQNFDVFSDVRSQMYKGGGKQYDSVKKAVDGTRGEVLTYQDKLFFTYYHANCGGGTDDVRSWNPGAASIKPLSGASCKTDSHSKSYKWQMNIPRSKVENYAKRVGLSGTLKSLKIARKTDTGRATNITIRTSKGSKTVPCGNFRLAVGIRSCKITKLSVRKNDVHFEGKGYGHGIGMCQDGANGMAKDGKNYKKILKNYYPGSEIKNISNYYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC60</accession>
    <name>A0A1Y4DC60_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56162">
        <property type="protein sequence ID" value="OUO56162"/>
        <property type="gene ID" value="B5F75_05970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012237996" evidence="1">
        <location>
            <begin position="20"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="251" mass="28523" checksum="901B2A510FA1762A" modified="2017-08-30" version="1">MRKHFFTLCALFCVLPSCAQLQENLQVVDLLPTENITSLEIKPRFKAKHDSANDISSTIEIKPSFKLNRHWKFGAEIPIARVGNDTAAAKGLGDIMVSGSYVDYTPSKVFSYGLAMELTTPTATDRSLGDGKWVAEPEIFTVWKLNSSFFIEAEYRHIFSFAGSSRRDDINESRYRMIFGLIGPDGWWFEFDPRYTVDYQNPGEAELIGEFELGTMVNVGSSMYVRGGWHLAGNKYSYDWELMLGFKILYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC68</accession>
    <name>A0A1Y4DC68_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56172">
        <property type="protein sequence ID" value="OUO56172"/>
        <property type="gene ID" value="B5F75_06020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="200"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="409" mass="45007" checksum="3E11C6BF18F328C9" modified="2017-08-30" version="1">MEKDLLKKIDSYKQTVIDLQTHMIACPAVSPHSGGLGENAKAAYLMSVLKQMKFDELYMINIKDPKAKDGIRPNIVAKYYGQNKQKTMWVMAHMDVVPPGDLSLWKTDPFKAVVKGDKIYGRGSEDNQQGLVSGVLAVKAMMDCGVRPPCNYALLLNADEEIGSVYGISAILKKHGKTFGKEDVFLVPDGGNAEGTMVEVAEKNMLWVKFTVCGVQTHASTPHSGINAHRASAYFVTKLDDLYKKFNKKDKLFAPESASTFEPTKREANVPNVNTIPGTDVFYLDCRILPCYSNEEVLKEIAKIAKGVEKQFKVKIKIEPVINEGSKPTDKNALVVKLTHTAVKSVYKNTPRTMGVGGGTVGAYLRNAGYPAVVYSKLDEMAHQPNEYSSIKNTLGDAKVFALVSLNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCA4</accession>
    <name>A0A1Y4DCA4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56505">
        <property type="protein sequence ID" value="OUO56505"/>
        <property type="gene ID" value="B5F75_04740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="150" mass="16327" checksum="3FE8184250FBDDAA" modified="2017-08-30" version="1">MKQGFTLIELLVVVLIIGILSSVALPQYEKSVERARAAEAVVTTKNILDAAAIYATTYRTCPTSLSDLDVKVTAETKNWIFGVNQLGTRNCAATVADKEGNFEAYRVFVKNEAESDMPSGSIFWNCQGGSCDDFFTAINVKPVAGTQNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCD7</accession>
    <name>A0A1Y4DCD7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_02980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56824">
        <property type="protein sequence ID" value="OUO56824"/>
        <property type="gene ID" value="B5F75_02980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="26958" checksum="A3422D13DFEE9297" modified="2017-08-30" version="1">MNSYEKTTLLFTFLTLLFAGLSSSVYAQKLPIGSKGFESLSRSIFMKEGGYSTHFPKFYKDLSSSLGKQMLSRAELREITRIYLHSQVPVQSAYKIMLARLQQPPALNLPSDVAFISLDNVKFVSRAVWKRDNLGTDQELLDLQRTLVANLAKYPNKQLTLKEFYYVVSKYTFEGPNFIKGFLETLPNRPILTRVQLSGAGKEPLDVFVYQDQAAKVIELYYAGKPFQIQKGKVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCF6</accession>
    <name>A0A1Y4DCF6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56272">
        <property type="protein sequence ID" value="OUO56272"/>
        <property type="gene ID" value="B5F75_06555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012441166" evidence="3">
        <location>
            <begin position="27"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1225"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1105"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1182"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1245" mass="139447" checksum="152695990D7ECC33" modified="2017-08-30" version="1">MQSFLCRVMALVFLFNCMLPAPGAWAQPRVSSDQIRQHVDQFVTEYLESSVAAASEELQYAQTPAEIATAITKLHKAVEERAAAKKQEEAKRQKLKESLVAPRSSTYVAPPVNPYKVFKSLNQNEVLQKLAKDELTVDDMINYIDPFEPADYNLQNLIYASEVLGNSIDAVLVQPDELVISQMNGLILFAQLRVLYRLEKLSKKAPASIYDAMALGSLRITLWKLHNFYVQTGQEDPLLAPEIGDPLSNSSIPAPQFNRELPWIVMNSWTQREIPFQLPPDIYQQINHQFLTELSTIKSHNPKEGSAEYQVMLSLADYATVYAMLEDPSQITPLVKLFDEGPKRSMRGKVVPGKFQQPYSPVLNDIFTSVYESVKYLVSDSAVWSQIIFMLKDFSDPAQYSLPTNIFALEAASLMYSQSQNCQAAAGAAAADYPVFLRCNSGNMQNDTLRPLFAQRTADLYAPLTRTHYLGIEDYGLDSQQMQMLADKLAFIYNGFANDELKWDYSRPRMKGSYVLDKGEDGKSLILNDKNSVPRLVPINRGHQFQLPDGSLKTISGFARMSDGTWVEMQLKNGLNAKKASDEANAKFFWFVGNAIFWIYGGEVLTFIGTAYRTTKGAMLALPKALKAAAQANKGRRALSFGVEIQKGVRFANLAKTLKKNAVTLQVERITEKTVKGSQKRMPAPQSYTPAMESNFKTITTQHALEGKYSKWNPKRWVGKEPAPITRFSFEQPIPGFGGVRQGTVEVTGTSLDKGVRSWDDWRKLRSSFRPLDVPPPNTSTEALSTFTRGFRSSADPKAIVFPRFYDYTTRKGLIQELLLTNAITKAAKGGAFNAWVPIKTPVFEGTAGTASGETVTWWNVTRLGAPGNELAAGFNHIVLTPAIGGKAARITSIDPTKLKNAIEIPLQRVTSNTWQPTVIHHYFNEVERTGIGKYLLPKYVPNANYWQTAKSNWRFALPVLKNTASNTRFWQGLVGNMVFFGTWAGLDMVTYPSMQGWIMSAAKEDQEKAMAKFGDAFDPEKLKEDVQRQEEQAQQAGVDASQNASLSTYQDVSAAVKQSSEGASLTFPIISVRHALPEGFGNLSFVTEQDEAKLAQMASQLQLNRALVKQAQAQQEKFAQAEKEMKEEYLQMILATVEIDQASYEDYASRYGGENYKKDITAIFNEYKKRITQTMNSDEPLETVNNKLNTIQQDIQNKLTQKIEEIARMIELLQQQAVEEEEYLPYGDDGGTEGYFEETPVEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG9</accession>
    <name>A0A1Y4DCG9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">B5F75_03135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56854">
        <property type="protein sequence ID" value="OUO56854"/>
        <property type="gene ID" value="B5F75_03135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="296" mass="33137" checksum="FA1598C3EE933FE7" modified="2017-08-30" version="1">MSENWVHIPIMAPLIADFLLTNPQGVYVDGTLGLGGHTKFFLSRLGPQARILGFDKDEEALQMARQRVNDPRLIAFHASYTQAPQELHKLGLAGADGALFDLGLSSYQLDNPQRGFSIVHDGPLDMRFDRQNPLSAQVIVNTWPMDELERILKEYGEERNATAIALAIMKARRQQPLQTTAQLAKLVEEVYGGKRGKTHPATQTFQALRIACNRELETVESALGALGDIVKPGGRAAILTFHSLEDRLVKTRFKELARSGEWLLVNKHAISAPYEEVRQNRRARSAKLRVIERIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI0</accession>
    <name>A0A1Y4DCI0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56813">
        <property type="protein sequence ID" value="OUO56813"/>
        <property type="gene ID" value="B5F75_02920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011569" evidence="1">
        <location>
            <begin position="24"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="83"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="340" mass="37762" checksum="6C0D9657004FA0CB" modified="2017-08-30" version="1">MKKILIGLLPVLCFLGGNTMVNAKTWDKTFAKSDLVTVKKVSFKNRFGIKLAGDLYAPKSIKKGEKLPAIALSGPFGAVKEQASGLYAQTLAQRGFITLAFDPSYTGESSGKPRNIASPDINTEDFSAAVDFLSTQKNVNPQQIGILGICGFGGFAINAAAMDTRIKATVTSTMYDMTRVSAKGYFDAMDADARYAQKEQLNAQRTRDFESGTYAPQPGLPEKLTGQEPWFVQDYWHYYKTPRGFHKRSINSNGNWTMTSTLSLMNLPILAYSNEIRSAVLMIHGEKAHSRYFSEDAFKKLTGDNKELLIIPGATHVDLYDNLQKIPFDKIEKFFKDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI1</accession>
    <name>A0A1Y4DCI1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56302">
        <property type="protein sequence ID" value="OUO56302"/>
        <property type="gene ID" value="B5F75_06715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="64"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="156" mass="16923" checksum="55EC05F0C58636B0" modified="2017-08-30" version="1">MTAVSKTQLYHDLLRQAQALLEIERDPVANMANLAAVLYNGLPQINWAGFYVLKENVLVLGPFQGKPACVRIALGKGVCGTAAQTQGIQCVADVHAFAGHIACDSASRSEVVLPVFKNKSLWGVLDIDAPVQARFDEEDCKNLAEIVRLFEQNSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCV0</accession>
    <name>A0A1Y4DCV0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56994">
        <property type="protein sequence ID" value="OUO56994"/>
        <property type="gene ID" value="B5F75_03865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="153" mass="17282" checksum="1546BB08FAB1277A" modified="2017-08-30" version="1">MKKGFTLIELLVVVLIIGILASIAMPYYFNAVESARMTEVVMLWGRQKNYVTGKNLTQDQADRLTERLQKSNLKNYTGYAYCRAKDDANEPCWEAVFTLKNPDAHSQYKLTTTRNFLSLACVGLNQAGKEFCESQAGPEEPITLDGEEAYLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDS3</accession>
    <name>A0A1Y4DDS3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57247">
        <property type="protein sequence ID" value="OUO57247"/>
        <property type="gene ID" value="B5F75_00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="165" mass="19114" checksum="B1200F4E45CE0707" modified="2017-08-30" version="1">MQRTLSLLSKISNAGNSFITAKLRERHYGQLAPSHGDILILLYKYKKITMQEIAAKIFRTKATVTVLVNKLEKMDFLKREKSPADSRITYISLSEKGIKFKAVFDEISKELNQMLYQNFTAGQIERLDHTLEKMLKNTSGHSPKNRERSRSDKQAYKNTKRHCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW6</accession>
    <name>A0A1Y4DDW6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57065">
        <property type="protein sequence ID" value="OUO57065"/>
        <property type="gene ID" value="B5F75_04250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012169747" evidence="2">
        <location>
            <begin position="28"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="248" mass="27029" checksum="32C1621B9D12C30C" modified="2017-08-30" version="1">MTNKKFITKISLAVLLLSVLLPSSAFAKKTRLVAVSADVVEISGTMQSVKGFSWNQLFDFEEATIPGILSLGEFERKTAVTTRLRLMETEGRAQVLSNPKIVTSSGNSAKITVGGKVPIPIVNNQGVGSQLEEYGILLNVLPTIIPERNNIIDLQVQLSVSTVDYSRTVVIGTATAPSFTNRDVETHVELNSGETLVIGGLKNSSRNVSEDRVPFLGRIPLIGLLFKNKDVTEEQRSLFLFITVEIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDX9</accession>
    <name>A0A1Y4DDX9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="9">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ileS</name>
        <name evidence="13" type="ORF">B5F75_00580</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57307">
        <property type="protein sequence ID" value="OUO57307"/>
        <property type="gene ID" value="B5F75_00580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07960">
        <property type="entry name" value="Anticodon_Ia_Ile_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02002">
        <property type="entry name" value="Ile_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033708">
        <property type="entry name" value="Anticodon_Ile_BEm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023585">
        <property type="entry name" value="Ile-tRNA-ligase_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="29"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="12">
        <location>
            <begin position="689"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="606"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="565"/>
        </location>
        <ligand>
            <name>L-isoleucyl-5'-AMP</name>
            <dbReference type="ChEBI" id="CHEBI:178002"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="609"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="897"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="900"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="917"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="920"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="939" mass="106383" checksum="9A2A8F96B5ABFFC1" modified="2017-08-30" version="1">MAKNKYSHTVLLPKTDFPMRAGLAQKEPKILEFWQSIHLYEAMLKKNEAGKHFVLHDGPPYANGKIHIGHALDKTIKDIIIKSRAMTGYYTPYVPGWDCHGLPIEQALLKELKQDKKHITDVPAFRKKARAFAAKFIDLQRQGFKRLGVQGDWDNPYLTMSPRYEGITIGVFLDLIEKGYVYKGQKTITWCSHCETALADAETEYKDVKSSSIYLRFKLVDPKKEIFGDLDYTKPVSLAVWTTTPWTIPSNMAAAVSNTEDYAVLKDEKTGEYYIVAEKLAEEFLKNTGLDCTQAGKVAGADLVGLKYYHPLTHKENPVIWTDFVTMDAGVGIVHIAPGHGEDDFRAGKQWGLETFCPVDEKGCYTKEAGVFEGMHVFDANPLMVKKLDELGALIKEQEITHSYPHCWRCHNPIIFRATEQWFMSIDKDGLRQKLMDNLSNVKFYPAGGEERMRSMIALRPDWCLSRQRFWGTPVTVLYCKKCGKPQVNHELFAFIKERAMKEGSDFWFIDPVEKLMPQGYHCECGCGEFRKETDILDVWLDSGVSWAAVVKDRGMSFPADVYSEGSDQHRGWFQSSYIPSFTLEGTAPFKTILTHGMVLDQQGRPMHKSLGNSVDPEDVINKYGADILRLWVAFSDYQGDVRISDEILGGPVDTYRKIRNTVRYALGNLSDYDPALHRVPAKELAEMDQYMLGRLNELIQEVHAGYSEFNFRRAIRAITDFCILDLSSFMLDASKDRLYTLGASSAARRSAQTVLAEIAVTLLQLMAPVLSFTAEEAWQELRKTALGRDLPQSIFLSNMPANASMIPDVKLEEKWNKIRRVRETVQKVLEETRQKGVIGSSLEAKVTFKTSNPEMKAFLEETKALWPEIAIVSEVEIADGKEELEVTAEHAAGQKCARCWQWKREVGSVPGHADLCARCADVLEKEGIKVEEEEQVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDY6</accession>
    <name>A0A1Y4DDY6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">B5F75_00300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57256">
        <property type="protein sequence ID" value="OUO57256"/>
        <property type="gene ID" value="B5F75_00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="22"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OUO57256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="212" mass="22956" checksum="DCFD46DF65FF6621" modified="2017-08-30" version="1">MPTTLQDFDKKQAIRLEANFIVGIDEAGRGPLAGPVVACACFIPPAMASNFTEVNDSKKLSEKKREMLFQKLVGSVPYGIGFASAAEIDRLNILQATFLAMRRAAYKFSNLPDSVALIDGPYPAAGLTMRQTPVVDGDAKSLAIAAASIIAKVTRDHYMNILDRLYPGYGFAGHKGYGTAKHMQALRALGPCREHRRSFAPVGKLLNPSFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE00</accession>
    <name>A0A1Y4DE00_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bifunctional enzyme IspD/IspF</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase</fullName>
                <ecNumber evidence="10">2.7.7.60</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">4-diphosphocytidyl-2C-methyl-D-erythritol synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="10">MEP cytidylyltransferase</fullName>
                <shortName evidence="10">MCT</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
                <shortName evidence="10">MECDP-synthase</shortName>
                <shortName evidence="10">MECPP-synthase</shortName>
                <shortName evidence="10">MECPS</shortName>
                <ecNumber evidence="10">4.6.1.12</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">ispDF</name>
        <name evidence="12" type="ORF">B5F75_00800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2-C-methyl-D-erythritol 4-phosphate + CTP + H(+) = 4-CDP-2-C-methyl-D-erythritol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="EC" id="2.7.7.60"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the IspF family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="10"/>
    <dbReference type="EC" id="4.6.1.12" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57344">
        <property type="protein sequence ID" value="OUO57344"/>
        <property type="gene ID" value="B5F75_00800"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02516">
        <property type="entry name" value="CDP-ME_synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00108">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01520">
        <property type="entry name" value="IspDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001228">
        <property type="entry name" value="IspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026596">
        <property type="entry name" value="IspD/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00453">
        <property type="entry name" value="ispD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YgbB" evidence="11">
        <location>
            <begin position="225"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase" evidence="10">
        <location>
            <begin position="225"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="10">
        <location>
            <begin position="231"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="10">
        <location>
            <begin position="257"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="site" description="Positions MEP for the nucleophilic attack" evidence="10">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="383" mass="41674" checksum="9D685996016816B6" modified="2017-08-30" version="1">MNRTGFSSAVLVAGGSGKRMGRPKQMLPLGGKPVLVRTIEAFQKCPDVREIVVVTPPENRAELNKYFTDLIYADPGDTRLESVKNGFAQTSAAAQTIAVHDGARPLVNPQHIEQCLQAALQFGAAVLAVPVKDTIKVGQNGVVEKTLDRSVLWAAQTPQCYRREVLARALEQFGQKKDATDESQLVEKTGVAVHLVPSDYKNNKITTPEDLVFAEALVEEKTVYRTGFGFDLHRLEPGRKLYVGGVEIPHTKGFLGHSDGDLVLHALCDAVLGALCAGEIGILFPPTDDSIKGISSVTIAKKVLEIVRAHHAEIDHIDATIITQEPKMKPHYDAVRHSLAKVFEMPVERVSFKSKSHEHVGEIGRGEAAMCQAVATLKLRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE01</accession>
    <name>A0A1Y4DE01_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aldehyde-alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57276">
        <property type="protein sequence ID" value="OUO57276"/>
        <property type="gene ID" value="B5F75_00405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08178">
        <property type="entry name" value="AAD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034789">
        <property type="entry name" value="AAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012079">
        <property type="entry name" value="Bifunc_Ald-ADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000111">
        <property type="entry name" value="ALDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="17"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-ADH" evidence="4">
        <location>
            <begin position="465"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="879" mass="96093" checksum="F347BC38CC9189F6" modified="2017-08-30" version="1">MAEKKTAPAVATPEELAHLDQIVSKVKEAQRVYATYTQEQVDKIFRAAAIAAAQNRIPLSKLAVEETGMGVMEDKVIKNQFASEYIYNQYKDTKTCGVLSDDDAFGFRQVAEPIGLIAGIIPTTNPTSTAIFKSLLALKTRNGIVFSPHPRAKKCTIAAAKIVLDAAVEAGAPAGIIGWIENPTMPLSNALMHHKDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDATANIKMAVSSVIMSKTFDNGMICASEQSVIVEDPVYDKVKEEFIARGCHFVTGKDRKKLADTIVINGKLNSAIVGQSAEKIAEMAGIKVPAGTKILIAEAKEVSDQEPFAREKLSPVLGFYRAKDFKSAAQLAKDLILYGGAGHTSVLYTDEANEDHIDYFKDMPTARTLINMPSSQGAIGDVYNFKLAPSLTLGCGSWGGNSVSENIGVKHLMNVKSVAERRENMYWYKVPSKIYFKRGALPQALAELSDKHRAYIITDKTMEQLGHVRAVADVLESLNIKFRVFSNVLPDPNISNVQEALNIANSWQPDMIIALGGGSAIDEGKMVWLMYENPDTSFEDIAMRFMDIRKRIYAAPPLGKKAVMVAIPTTSGTGSEVTPFTIITDEKTGTKYAITDYALTPDMAIIDPEFVLNMPKSLTAFSGLDVLTHAIEAYTSVYATNFTDGQALEAMRLVFKYLEKSYTNGAKDINAREKMHYAATIAGMAFANAFLGLSHSMAHKLGAMYHVPHGLANALLLSYVIEFNATDKPTKQGLFPQYKYPFVKGRYGKIVDFLLPHNNLGDDKDAKVQKLIDMVEDLKHKLNIPRSIKEYGIPEKEFLDNLDKLSELAFDDQCTGGNARYPLISEIKDLYLKAYYGEPVKHKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE32</accession>
    <name>A0A1Y4DE32_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57383">
        <property type="protein sequence ID" value="OUO57383"/>
        <property type="gene ID" value="B5F75_01010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012711890" evidence="2">
        <location>
            <begin position="19"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="193" mass="21704" checksum="B2707290A2365C07" modified="2017-08-30" version="1">MKKFLSVLCAAAALAACASEGAVYKPQAQIMPQHIKKIAVRQILNKTEVFALEDKFYNELYDEFLRDGSYQIVSENNGAEGVVVTTISRYLNVPIQYDSQLIPTVYRMDIWLDVVFMDKTTNAPVWREPAFLGTQIYAASTLPGGMTEVQARDVVFEKLSKDIVKRTVEGFGSVMSENKKKVMNNPEYTTITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB5</accession>
    <name>A0A1Y4DEB5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">B5F75_07190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56059">
        <property type="protein sequence ID" value="OUO56059"/>
        <property type="gene ID" value="B5F75_07190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="57"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="124" mass="12834" checksum="339718E6B09C3E89" modified="2017-08-30" version="1">MTKEELVNAIAELTVLELSELVKAIEEKFGVKAAAPAVAVAAAAAPAAAAAEEKDEFNVVLTAVDAAKKISVIKVVREITGLGLKEAKDLVEGAPKAVKENVAKAEAEELKKKITEAGGTVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC4</accession>
    <name>A0A1Y4DEC4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PNP_UDP_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57427">
        <property type="protein sequence ID" value="OUO57427"/>
        <property type="gene ID" value="B5F75_01250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="84"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="248" mass="27425" checksum="118BF4A847E0506B" modified="2017-08-30" version="1">MTLLFPKNKKPSLKEISTPAGYVRHVAAGLKLPSKAILCPISSLTRYVESQAKYKKYNCEADIYALSTEDLCYVTNFGSGAPGMTMALEVLIALGVKEFVFIGLAGSLQEEVEPADIVLCQEALCDDGTSPCYTARETSKPNKTLFAKLAKALRAAGKNFHIGRNWTTDAIFRETKEEVKHYQKQDVLTVEMETAAFYAVCAKRKAKGAAAFVVSDKLDRLKWEPHFGEKPIFRALETVFDAARKALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEG8</accession>
    <name>A0A1Y4DEG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57544">
        <property type="protein sequence ID" value="OUO57544"/>
        <property type="gene ID" value="B5F75_01865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="232" mass="26314" checksum="1B84467DC9C49449" modified="2017-08-30" version="1">MPFSARSVRFVCFDADDTLWKNEEFYRQSERDFARLMAPFLSQQQAIDRLFQTEMDNLETFGYGAKSCMLSMMQTALEILPPQQAAGALKEILQIGRRLILHPVEVLPGVKDTLEKLTGKYHLSVITKGDLLDQQRKLERSGLQPLFNHVEIVSDKTPAAYRALFVRLNAKPQEVLMVGNSLRSDIFPALQAGAQAAYQPSPFNWKHEEMPEPQDPPYLKIASLPDLLPVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEI9</accession>
    <name>A0A1Y4DEI9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57497">
        <property type="protein sequence ID" value="OUO57497"/>
        <property type="gene ID" value="B5F75_01620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="19234" checksum="212E60CEE5FD6055" modified="2017-08-30" version="1">MKQAYVNMRNFWLDVKNLENRKGVIEIGPDKISVAGIEMAMQDGNEVKHLFLATNSLGDSSLYFENNSKSGLGGIIGGHGHEALQETAARMLAHASKLTGEMTAVAAGGELPPPSSPQMVRLFAVSKEKLFYTELPEVNLRNPENNFYPFFAYSQQTLGLFREQETQASSKPGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK0</accession>
    <name>A0A1Y4DEK0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57507">
        <property type="protein sequence ID" value="OUO57507"/>
        <property type="gene ID" value="B5F75_01670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="168"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="483" mass="52285" checksum="FECAF4F2476B03BD" modified="2017-08-30" version="1">MNWKQLGTVLAAVWLGGCMLGPNYKQPDLDLPAGQTAENFSVFTNSKWWEVFQDPVLNQLEADALEHNKDLQAAIARVDQARAEVGIATADQLPSLSAAAESGRAGDQAGSGQSKSTANVSVSYELDLWGKYRRLSEAAQAQLLASEAARDTVRLTLTADVAKNYFSLRMLDAQLEIAQRTLQARQENVRIYTSRYQNGYCTEVDLKRVEANMASVQAQEQQLRLKIAQTETALSVLVGKSPREIVENNTPRGKSLSEITLIPNVPEGLPSDLLARRPDVRSVEGQLMAANANIGAARAAYFPSIPLTASAGYASGALNNLFTGSSGVWAAGGQLLAPIFEGGKIRAANKKAEAQYRETLASYEKTVQGAFKEALDAISANQINREIFDSYKQQTEAMQRSYELTKKQEDAGLIGVTDLLDVEENLLSAEMNLATARNDELAAIVNLSKALGGGWNVQDGFGPYENLVKKQQAALDPQATAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEM0</accession>
    <name>A0A1Y4DEM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57537">
        <property type="protein sequence ID" value="OUO57537"/>
        <property type="gene ID" value="B5F75_01825"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="13"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="175" mass="19826" checksum="858D66B1D6778757" modified="2017-08-30" version="1">MPENPILERVLFSEQQLADRVAELGRQISADYRGKLPLFVGILRGCILFYSDLMKNISVDCNMDFMCLSSYSGTSSTGQVRTMLDLRESIKGRHVIIVEDIVDTGLTLNYLLGNLQNRGAASIEICCLLDKPCNRKVDVHPKYVGFTVENEFVIGYGLDYNELYRNLPYIGVFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN2</accession>
    <name>A0A1Y4DEN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57584">
        <property type="protein sequence ID" value="OUO57584"/>
        <property type="gene ID" value="B5F75_02075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="143" mass="15136" checksum="A20689FA1E8A177C" modified="2017-08-30" version="1">MKLKIREAILLVCALAALGTIPVFLSKDNPIEVSVPVLDAAKLAAKEAKAQKEAEESAAQAAMRRMVSCSVNEDCIIVDKDPCGCLVGPEGVTAINAAYTLDFNKFQSSLVTKACPEGAPSTERECSPSAQAVCQDNVCRISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEN4</accession>
    <name>A0A1Y4DEN4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57633">
        <property type="protein sequence ID" value="OUO57633"/>
        <property type="gene ID" value="B5F75_02330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012350569" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="35"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="238" mass="26540" checksum="030B09FFC8A7820E" modified="2017-08-30" version="1">MKKITLLAVFLSMLCAWPTTASAQGIEKGDQMVSVFLGSAAPLNDSGVSAYSVTGEAVDTSTLDWGDASTSYGVQYMYALTPHFALGAEYNGNNFGDAEYEREYFVDWNNWGESEVNSKMDVQNFMIAGRYTVNPQSKVRFYIPLGLGVASSKATFDFNEVINMAGRLDRTNASESKRTTSFTYYVGLGLEGTFSQNWIWGVEGRYQGFQFDYGKFSDEYGTKNLSYFALLLKLGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEP3</accession>
    <name>A0A1Y4DEP3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_00970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57375">
        <property type="protein sequence ID" value="OUO57375"/>
        <property type="gene ID" value="B5F75_00970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004622">
        <property type="entry name" value="DNA_pol_HolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00678">
        <property type="entry name" value="holB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="334" mass="36217" checksum="405A7A01B87395AC" modified="2017-08-30" version="1">MPFADILGQEKASSYLKKLAGAQKVPGALLFYGPDGVGKARAAVLFAQALNCLDPQARQTGDACGVCASCQAIAKGTHPDVTFVDFTYQARLEVKKDFSSKGYEDELEKEIAKQQHINVDTIRDVTAKSQQKAVGGGWKVLIIDQAQTMQGAAANALLKFIEEPPYKTVWILITNKRATMLKTILSRCQPLAFAPLSQENVTQILKNTGADVPDPDLCARYSGGSVSGALKAAEALELLQNGQFGTPQGPCSVAAGLSRTLVAARQEAQAVLDVLICALHRRWTQTQDPREQRRLQQVLNQFETYKRSIGRNVSPALVLETALMSLDGLNVQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DER2</accession>
    <name>A0A1Y4DER2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57395">
        <property type="protein sequence ID" value="OUO57395"/>
        <property type="gene ID" value="B5F75_01070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012599052" evidence="2">
        <location>
            <begin position="21"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="419" mass="46654" checksum="135E9DB97997803D" modified="2017-08-30" version="1">MNKLFITAVAVLFAAPCVCAADAAASLEFYKKQALTLSAEPTREERAFSKTLADNLGTWIKQNPTQPAVADALLLQARLYLRAEEDDRALVTLFTLRQQFPQVDMALLTPLMADAVLAVNPKERDSATALFMAVPDVKTTTPAQRQAQALYALSKLSGRSLYEPAAQAFEAFFVANPNYEATDMVELWYGDLHRVNGNYLAAISQYKKAGELYPKTPYRAASLRLIGDIYADNLKDTANAMATYTQVLREFPGSSETGIVYKHMAILDENNKQYDSALINYDKAIELLGTTPAAYEAYQGKADVYTKTKNYTEAYNTLHQTAAVFQQDEEKSTAALLKAADLARKKMRDDNKYIQSMEKALLAHPKGPNAPQLMYDLGRAYEQQSRNAQAVEIYKKLIINHPTDKLATRAQGRLSRLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU2</accession>
    <name>A0A1Y4DEU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_06370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56239">
        <property type="protein sequence ID" value="OUO56239"/>
        <property type="gene ID" value="B5F75_06370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="701"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="508"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="587"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="588"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1059" mass="116607" checksum="F4935CA7A2E94A31" modified="2017-08-30" version="1">MIKQWDVISRLDPKDQSRRYTLVTDGTEHDARLIAKKLAGYVQAPQPAAAPFVYAFELPADLDEDTLEKIRTAVREGVEQTNKVNQFVPGGILGDPLFNSEVTKDDKAFPTFVTLDPSESFFREPQDAPSVPPPAPQEEKPVADFQQQSVKINAEDTQQSIGLEKQTVSANPTGKEQSGEITISDKDMLIKDMEGTMLGQMPLEDIFSAETKYDMFLDLENQKLVKNSQVQREQKMNNLADGKGSLEDSFNIFEQKMKDQTCIIDLDDLNAITDRLPKKDMDFLKHTAHGEALQQTPAEQAEQPSAPAKPVQKPLPEPADAAQTPNQAPEIPDLARPTDNEPTPAVAEITPEPAESDGVEDPFEQIEKTARLKTQSGAAAAPQVPPAPPLQDLSAPVASVSLSAADEEPLNLGPSPEEASVTDFAEHPSHGEIPEEVAILNTVPPTQYSRKTVSPSAGAEDLPEITIRGQKIESLDKTFNLETTLNTEVMKHQYEKSFHDTTVTPAVKRPAAHPQPPAAAEKPQAPAEPKEKTAPVKLHLAGEKKPAEQPAAHPKISRSVTPGESDMEENQELKTTFRIRRKIDIPHAPAAPVPPPPAAPAAPQPAAPAAPAAKAPAQQPAQPKQPVSNRPAPKPAAANTIIEKTKTIDHSIEIPLSELKKHNWPLEVPLVPTYTLETMVMSVNRFAHATAISVIENPGKLYNPLVLHGATGTGKTHFLNAMAYAFSKKYGQENIFMTNGVRLSRGIQRYVMEGNIEKFEKFMDTVKVLLIDDIHLLAINEQNRMYISKLLNKFLQDQKQIVITSKYPPESLEKLEELIKFRLDSGWISELKPASGNTHFKIVKKMLLDNGVDLNDAQISAFFGGPHMTLGTVTRSIRRLKVLENLIFPHLPEAERSQAMIFEKLLATGGEDETSEVLTRDPETITSITTTGNGEWGRIGFFYPQNSSHMMNWMVFALQQRAKELGIEGGFEIAVRSSYATENIISSAFKIANLCDNKKLKGAVILGPALTVCDPSVRENFYDILTHMLEIMLIRCGIINYEDAKSPSTYVKVLSELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEV6</accession>
    <name>A0A1Y4DEV6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57654">
        <property type="protein sequence ID" value="OUO57654"/>
        <property type="gene ID" value="B5F75_02450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="9"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="487" mass="55707" checksum="22668E9FECD1C8BF" modified="2017-08-30" version="1">MRTNPHILEINTRSWLKRLEARYGHPLTLDQVPDEYWQRAKDLGFDAIWFMGVWKLSPAAEQIARSNPDIQAQIRAIKPDFKPEDITASPYAVYEYTVDEALGGDAALAALRGKLNALGINLLLDFVGNHTAIDSPTVTSDPDLYINTGTQEPHAHKDWFFKNANGVYIAHGRDPYFAPWTDTAQLNYFNPKTREFMLKNLLHVADLCDGVRCDMAMLSLNKVQRDTWWEFIGGNLPKEEFWHQALTAVHDKHPEFIFIAEVYWGLEWDIQELGFDYTYDKVLYDRLRFSNAENIKGHLGAEHLFQMRSIRFTANHDEEESLKAFGKEKSLAASTIIATLPGARMFHLFQLLGRPERMPIQYIKDDFQANMEVAQYYEKLLHIASDPAFHGGQWTLRDVASIAMGDDSNRNILAWQWKQRNTGKLIVINYSSAPANGRLSLKGVYGPDSQITEELTGEKITVTPQTLSQGYELHLKPYESKIFTYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEX3</accession>
    <name>A0A1Y4DEX3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56269">
        <property type="protein sequence ID" value="OUO56269"/>
        <property type="gene ID" value="B5F75_06540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="207" mass="23234" checksum="C319D02045112395" modified="2017-08-30" version="1">MEQLIETRTGLAIIFILALALFFLRKHSYNPFKKTLEKASAGDPQAQFEMGRLYYRGKHVAQDFVQALNWFDTAAKNGSVPAMNALAGMYHAGQGCEEPNPQKTFSWYQTAAHTGDFEARVNLAVCYLNGIGTEKNEAKGFEVMKAAADEKSPIAQTLTADLYERGLGTEKNEKLALHYYFLASKQGEPMAKRKIKKLQEEAMRQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF59</accession>
    <name>A0A1Y4DF59_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57282">
        <property type="protein sequence ID" value="OUO57282"/>
        <property type="gene ID" value="B5F75_00445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="21046" checksum="FF026C39202538D9" modified="2017-08-30" version="1">MRYAPLGVEHSKNGALLIGKAPHIAEFAWLNVMYPCATEAEICNLEKSLGTAIPKIYKDFLVNVANGFDIMNCTLAFHGCRTSYNRSDLDLWYPFNVEDIQKYGRPKNSSPAMFFFGTYKYDGSKLYLNTTDDKVYYCECYDATPLKSWNSLDEMIVSEIERIYTLFDEKGHQIDPSKPTTPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF87</accession>
    <name>A0A1Y4DF87_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_00610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57312">
        <property type="protein sequence ID" value="OUO57312"/>
        <property type="gene ID" value="B5F75_00610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="221" mass="24536" checksum="2381640FBAC5CFE6" modified="2017-08-30" version="1">MMVIHCEHLVKIYQTAQSFRALDDVSLDIEKGDFISIMGPSGCGKSTLLNILGLLDEPTSGEYLLNGVKTARMPDRTRSHFRCTNIGFIFQSFNLMPRLSVLQNIALPMRYNSLIPRKEILPRARELLRRVGLEQKAGNTPLQLSGGQCQRVACARALANRPEIILADEPTGNLDSKSGAEILNLLQELNQNGLTIIMVTHDEKIAAGARRIIRMKDGKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFG8</accession>
    <name>A0A1Y4DFG8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56429">
        <property type="protein sequence ID" value="OUO56429"/>
        <property type="gene ID" value="B5F75_04335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012192798" evidence="3">
        <location>
            <begin position="20"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="291"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="358"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="530"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="573" mass="61921" checksum="1AC44846A5E32696" modified="2017-08-30" version="1">MKKIGFVFVFALAALPLCAQTAQNTNDSYTGYEGLVLGERTPRSATDTIADQATQVPGDIYRGTLFGAEQKKYEGDTLGNRPRPTTKFVYDTSLVRAIKISDADRVRTLMYANVDVNEKNYAGITPLTIAAEKGNMEIIKMLVEDGNALVNEASSYGVTPLIAAAAAGNDEAVAYLVEQGANVSAKDDWGKTALIYAATLDNPKLVSSVIKLDKTAVNLPDNLGNTALIYAAQKGLLDNMKILLANGANANYRNPATGISAISAAAAEGNSAAIRMLVRTGKADVNISDLSGRTPIFYAVEQNQEDALRTLLSLGADVNAQDNNGVSVLMRASAKNRQDCVNILLRQKGINPNLKDFQDRTALIYSVYADELAPTQALLKAGADLNVRDSSQNTPLMSAIKAKNDRAALFFIQQGAELTAVNSSGENAFMLTEEYLPNSMTANVLKVKKAESYQDALQLQAQKLAEVRTLEQQLAQEEARVKELQEQQAAKAQQEAQAKEAALRAKLEAEYQEKAAQAMQNDPELIRLQQQLDAAKAQRQAAMQEEIDRKVEEQLNKTDAPAPSVLTENAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFV3</accession>
    <name>A0A1Y4DFV3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_17 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57552">
        <property type="protein sequence ID" value="OUO57552"/>
        <property type="gene ID" value="B5F75_01905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="32"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="84" mass="9583" checksum="234F170302910A73" modified="2017-08-30" version="1">MSFCPSTTSNSGAVYFNPFGVIKYGEAKMEELMTVEELAEYLRTTPGTVYTWKSMGIIPPKCVKKIGRKLLFIVREIEEWVNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG27</accession>
    <name>A0A1Y4DG27_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ZT_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_05300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56609">
        <property type="protein sequence ID" value="OUO56609"/>
        <property type="gene ID" value="B5F75_05300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="222"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="302" mass="32909" checksum="AA8C8A9D7943A854" modified="2017-08-30" version="1">MNLQARSAFAREITVKGMIINTVLCAAKFAAGVFGRSSAMVADAVHSLSDSLTDIVVLASLKFSTRPADQDHAYGHGRFETMATLVISVALFAVGAKILYNGILDIVRLAEGGTIARPHAIALWMAVLSIAVKEWLYRYTLKAAKQIGSSALEANAWHHRSDAMSSIGTLLGIGGAYFLGNKWTVLDPLAAVVVSFFIFEVAWNILKSASDELLDKSLGAQAETKITQVCRQAEPQACAHSIKTRKIGGYACLEFHVYLPDEWNLKRVHDATDKMEQALQQAFGQQTLVTIHPEPRSLDNNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DG35</accession>
    <name>A0A1Y4DG35_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgt</name>
        <name evidence="6" type="ORF">B5F75_05355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56619">
        <property type="protein sequence ID" value="OUO56619"/>
        <property type="gene ID" value="B5F75_05355"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="15"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="93"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="4">
        <location>
            <begin position="289"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="389" mass="44003" checksum="EEF910978A8DD7C9" modified="2017-08-30" version="1">MNSPFHILSKDPHSKARTGILYTKHGAVHTPVFMPVATQACVKALTDEDLKNAGAECLLSNTYHLYLRPTTPILQQMGGIHKFMHWDGSVLTDSGGFQVYSLSKFRKIKEEGVTFQSHHDGSKHLFTPENVIQFESEIGSDIWTMLDVCIHAKDPSKHDARQALNLTKRWAERAAKAYEQTVPQQHITQRADGSFEVGNSLLFGIIQGAIFPDLRKEAAQHMASLPTHGYCIGGLSLGETLEQMNESVLAVTDNLPENKPRYFMGLGTPVEILNSIERGVDMFDCVWPTRVARNGMAMTSTGRVNIKNAEYRTQDIPLDPECDCYTCRRYSRAYLCHLYRSAELTSHRLMSIHNIRFLIHLMERARQAIANGTFLAFKDEVIRKYQNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGQ2</accession>
    <name>A0A1Y4DGQ2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03110</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56849">
        <property type="protein sequence ID" value="OUO56849"/>
        <property type="gene ID" value="B5F75_03110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018365">
        <property type="entry name" value="Cell_cycle_FtsW-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00428">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="416" mass="46276" checksum="DE83914D2CECC11F" modified="2017-08-30" version="1">MVRLFNKAPKRRNNFIRKAPAEYKGRGASFRPSGTKPAPARGGWQPLQLDKRIAFITFAFVLFGLIFTYSSSAFDSTAYFKRQILFDTLGIAAALFLSQTYDKLQKLKIFSPMNLMYVTWVLLIVVLFTRAQANVHRWIDFGFFKLQPSEIAKVTLVIYIADYLNGVSGKLTKNWRLLIKPMAVAGITLGLILAEKDIGTPTLMGAVFVFMLLVAGARLKHLAVPAVVLAPLAIQQLFFVSYRRERIFSFLDPFATAGSSGYQLVQSFLAVGSGGWFGKGLGNSELKLEYLPAAHTDFIFSIMCEELGLVRVVVILVFFCWLLIRGISLARVAKTQFNGLVIFGLTITICMQAFFNMAMAIGLLPTKGIALPFFSYGGSSVIMTLVMMGIILNLAAVDNTQNNLREDITNYKNRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH20</accession>
    <name>A0A1Y4DH20_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">STN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_03790</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56979">
        <property type="protein sequence ID" value="OUO56979"/>
        <property type="gene ID" value="B5F75_03790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012034183" description="STN domain-containing protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="9">
        <location>
            <begin position="88"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="526" mass="55748" checksum="10B263998E808D88" modified="2017-08-30" version="1">MTNRLAVVLACVFSLGLTGTVSAQQARQTLPSDDTIALTEDTTVKLSGESDLYKETEVFSPLDRKVSIRVSNVPISAFLNSITTQAKINFIMSEEFANKKVTASLTRVTVREALDTLLRVHGLTYQRIGKSDSYVVTKRSSDAPDTITKIYTLSYISLQGIGSAQSELSSIMPQDVSTGGSSYSSSSTDTGIGVGGTGTSGTTDSYSGGAEITAIVKSMLSPVGKIAVDPRTNKLIITDVAEVFPQVENILAELDIKPPQILIEAQIVEVSKTSGLSLGFEYGGESGALVSMTAPSRVVDLDYIKGNGVKGWNFIFPTKDQMNSDSSESGGSSSSSSSSSDQTDEGGLLDFSAFNIVLKSLLTRGEAKYLGKPKVVTLNNKTATITTSTDATVGQTMSQSGSGSGEGMTTTSAERKRVGLTLQVTPQVNREGYVTLYVQPSYSDLVSSGFDFSKDTTTRAASTLVRVKNGQTVVIGGLLTSRETNQTRKVPLLGDIPILGWLFTSKTTSKSTTDLVIFITPTILAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DH52</accession>
    <name>A0A1Y4DH52_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56258">
        <property type="protein sequence ID" value="OUO56258"/>
        <property type="gene ID" value="B5F75_06470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="449" mass="47418" checksum="7B96221ECCDB4F57" modified="2017-08-30" version="1">MKTQRKKKAFTLTELLVVVIVIGVLAAVVLPKFSKVIETRKTTEAEELMAAVRTEQEKRCSLDQDYLSDLSKLSDIIPSTDTKNFVYSTNAEGTGIEAQSKGKFGYTLKMPSYKDGRLCCDNEEECLKLNKDYPLCSELIARADYQSGEECAGEKGPTVIACVGESTRSCGCQNKGTQSRTCDTTTGTWSAWGSCSISDVCQCTGTEPASTQTCNGCGTQSRSVTCDTTTGAWQTGAWGACSKTEAECSDPCSSHPFDLVGGREETALCCKGSSVYEPETGETFTDAAYCCGTVNVCCFYPDGTSGNCDPMSSVSLSEKNSYCKIAGNGSHAEYVCGIPSSGGTTPGTNCTWGSGQSVQQTVSIDYTAGDLFEKISSQSDITSSFSIAGTEGWTNPPTCNTGGTCDSSGALCNNNPYLSNCKVTSADSGGTPASYSCTLTYTSRSCTCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHC1</accession>
    <name>A0A1Y4DHC1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="10" type="ORF">B5F75_06855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56328">
        <property type="protein sequence ID" value="OUO56328"/>
        <property type="gene ID" value="B5F75_06855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="140" mass="14595" checksum="22558285E7D6BDFF" modified="2017-08-30" version="1">MAEEKVTTAAPAKAPAAKGRKKNAKAPVFGVVHIYCSFNNTIVTVSDDKGNTIAWSTAGSHGFKGTKKSTPFAAQITSHKAAEKAAAMGMREVAVKVCGPGQGRETAVRAVQQAGLTVSSIKDITPIPHNGCRPPKARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHY1</accession>
    <name>A0A1Y4DHY1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_04970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56548">
        <property type="protein sequence ID" value="OUO56548"/>
        <property type="gene ID" value="B5F75_04970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="5">
        <location>
            <begin position="10"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="140"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="352" mass="39268" checksum="6DD2022906966EBB" modified="2017-08-30" version="1">MAEKNYMNERFAKLKKLLRKNKLDGFIVTNNLDQFYLTNFFFYPNEAVFLIHKKGVTCFTRELYVESFGKFAPQIEVIGDENRIVSAIDKARKLGLARPGFDAAKETYVSGGLLRASGFVEAGSLITTLRENKDAAELKLLRESNRIAYLTYEYIKPRVKTGMTEFEVAAEMERFMRAHGATTTSFYTIVAFGENTANPHHETSARKLKAEDAVLMDFGCVYKGYCSDITRSWWHGKKEPAEYTKIWHIVDKARKQGIKAVGIGVPTKKVDATSRGIISAAGYGQYFTHGTGHGVGIEIHEDPYNSQQSAAILSEGNIVTVEPGIYLPGKYGVRLEDTVAVAKSGAKILTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI18</accession>
    <name>A0A1Y4DI18_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_00590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 6">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57309">
        <property type="protein sequence ID" value="OUO57309"/>
        <property type="gene ID" value="B5F75_00590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="7">
        <location>
            <begin position="204"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="5">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="449" mass="49747" checksum="421C39DF7A7E752A" modified="2017-08-30" version="1">MDTNTYTEQFLAALTKRDPAQKVFHQAVFEVVSTLKPVLEQKPLYIKERILERIVEPERTIIFRVPWQDDKGEIHVNRGFRVQYNSALGPYKGGMRFHETVTQDVLKFLGFEQVFKNSLTTLPLGGGKGGSDFDTRGKSDSEVMRFCHSFINELYHHIGYHTDIPAGDLGCGAREIGYMFGQYKKLTNDFTGAFTGKKPNWGGSLLRPEATGYGVAYFAQNMLATKGDSLQHKTCIVSGTGNVGIYAIEKLTQLGGKVVGFMDYDGSIYDENGVDAEKLAFLKDLVFVRRGSLKEYDKKFKGAHFRPGKKTWDIPCDVACPTACENELHTEDAKLLLKNGCKCVCEGSNMPCTPGAIEAFQEAGILYSPGKASNAGGVAVSGLEMTQNSMRVYWTREEVDQYLQRIMNNIHHSCLSAAEEYGMKGNYMAGANIAGFIKVADAMIDQGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI39</accession>
    <name>A0A1Y4DI39_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57329">
        <property type="protein sequence ID" value="OUO57329"/>
        <property type="gene ID" value="B5F75_00705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="19"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="267" mass="29637" checksum="91BA0D611D6AA9E8" modified="2017-08-30" version="1">MATSLIFLGTGNALVTKCYNTCFALQNGDEFFLTDAGGGNGILAQLEKARIPLPQIRSLFVTHGHTDHILGVIWVIRLAASLFTRGKHPGLTIYCHDECEKKLRAFCQMTLTAKLQAVLDNGVRFVCLQDGDSFQAAGFACTAFDIHSTKTKQFGYRAVLPDGQTLVCLGDEPYNPACQRYAQQADWLLSEAFCLFSEREQFKPYEKHHSTARDAACTAAQLGAKNLVLYHTQDNCLPERKRLYTAEARQCFSGPVYVPDDLQTIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI56</accession>
    <name>A0A1Y4DI56_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaE</name>
        <name evidence="2" type="ORF">B5F75_05405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56628">
        <property type="protein sequence ID" value="OUO56628"/>
        <property type="gene ID" value="B5F75_05405"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="196" mass="21812" checksum="6F89E6ADEC58C4FE" modified="2017-08-30" version="1">MNLRAKDKLVVGLTGSILSGKSTALSYFARNGAGVISADELVRQLYQAPAVQKQIVRWFGSCKPAEVARCVFADESARRKLEKYLHPKVWALAAKQIKQAPQPIIVFEVPLLFEAGWNRKTDLTITLLGDERTLPARLKARGLTLAEYKRRVAGQLPESEKVRRADIVLANRGSKTDLGLKIKRLCQALNTIYALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIC3</accession>
    <name>A0A1Y4DIC3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57409">
        <property type="protein sequence ID" value="OUO57409"/>
        <property type="gene ID" value="B5F75_01145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="280"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="361" mass="40817" checksum="CD75FE6B6A2CF394" modified="2017-08-30" version="1">MRIYFYIARKFWGPFFFALGVFTALVVLGDTFEKMKNLGNGVTTMMDLLSYSLVTFPNWLATIMPVACLLGAISVISEMVANGEWTACVASGFAPRQLFKPVILCILGVVLATMVLQEFVIPPLNAKSERIYNTRINPSEDPFNPDAERDVILKISPNQMLFAKEVNLKEGTMKRVSLDTYDSGWNIANQIVADQMLWNPDTKSWLFSKGIQRVFIDSMDTTEESFETADSPVNLNPSEMAIDRTDNKLLSIRELYKRIHFFKKSGLSSYAAQTMLQSKLATPFVTLIMCLLGMPFAISVRRKSKILNIIASLVIAFTFWWLITMFTSIGENGYINPYLAGWGPVLVFAVVVFFEFKWLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIK7</accession>
    <name>A0A1Y4DIK7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56150">
        <property type="protein sequence ID" value="OUO56150"/>
        <property type="gene ID" value="B5F75_05895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08186">
        <property type="entry name" value="Fe-ADH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045910">
        <property type="entry name" value="AdhA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="20"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="404" mass="43451" checksum="6F81F0AE79042EC6" modified="2017-08-30" version="1">MWEKDIDINEVREIRSRTLVYFGVGAINKISDICKDLKAKGITKLVVVTGHGAYKKTGAWDHVTKAFAENGITYVHYDKVTPNPNTHHVNEAAKMAADFGAQAMLAIGGGSAIDAGKSVAILMKNPGHTAEELYEFKFTPTEAAPIIAINLTHGTGSEANRFAVVSIEEKNFKPAIAYDCIYPLYSIDDPALMTGLAENQTRYVSIDAVNHVVEASTTKVTSPYAIDLAVAVVKLVNEYLPVALKDPTNLEARYFLAYAALIAGISFDNGMLHYTHALEHPLSGVNPHLTHGLGLAMLLPAVIKNIYPAKPATLADVLAPIVPGLTGCACEAEKAAQGVEKWLFSVGSTHKLEDEGFKSSDVDKLVDLAFNTPSLGGLLGIAPTEATKEAVRTIYTESLKPYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIN0</accession>
    <name>A0A1Y4DIN0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PhoU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_02790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56788">
        <property type="protein sequence ID" value="OUO56788"/>
        <property type="gene ID" value="B5F75_02790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015114">
        <property type="term" value="F:phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005436">
        <property type="term" value="F:sodium:phosphate symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044341">
        <property type="term" value="P:sodium-dependent phosphate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003841">
        <property type="entry name" value="Na/Pi_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004633">
        <property type="entry name" value="NaPi_cotrn-rel/YqeW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030147">
        <property type="entry name" value="NptA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010">
        <property type="entry name" value="PTHR10010"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10010:SF46">
        <property type="entry name" value="PTHR10010:SF46"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02690">
        <property type="entry name" value="Na_Pi_cotrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00704">
        <property type="entry name" value="NaPi_cotrn_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="8">
        <location>
            <begin position="366"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="596" mass="66452" checksum="8736B4B517B4C303" modified="2017-08-30" version="1">MSTLLNTLNLLGGLAIFLFGMKIMSDGLQKVSGEKMRQLLGIATTNRFAATACGALVTSIIQSSSATTVMVVGFASAGLLTLHQSLGVIFGANIGTTMTAWIVSLFGFKMQISLFALPVIAVGFFAQFIPRFIVVRRIGETMVGFGLLFLGLDIMKNAIPADFAQNPQVVAWISRFQPNNLFNLLILIFSGTILTVILQSSSAVMAMTLTCAAAGIIDFPTSCALVLGENIGTTVTANLAAIGASKNARRAALGHFLFNVIGVFWVACIFKHFVHFVDWLVPGSPYTKETEVLTAVLPYHISAFHTTFNVLNTMLMLPLINQLAKLTYLIIPKSKREDKKEHELIYLSTRFTQTPELALIAVRKEVERMMSFVTKMTDKLIHAVKVDDEKMFQRLIDDVKEAEKTTDVLEHKINLYLTSLSHGNLSRHAVAQAFSLFDVLNSIERMGDCGEKIARILEKFHTKQPFAQADVNDLEIIAKLTKEITKRTRRVLVDFQQPTRQWHDQAERTFAEAIHDEEQLNALRKRLLRDRRERINAGQEASPDSITAYADILNNFERIGDYAMRVNENILGMRAEERVYHNPMVEQQEPALPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIV8</accession>
    <name>A0A1Y4DIV8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">B5F75_02210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57609">
        <property type="protein sequence ID" value="OUO57609"/>
        <property type="gene ID" value="B5F75_02210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="100"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="224" mass="23771" checksum="02C929B8297B50DF" modified="2017-08-30" version="1">MEKVTISAAAREGIGVKGALSKIRAEKKIPAVIYGGQKEPVSVTVSVKDLDKIVKAGKNTLVEMDLNGAKELALVKEIQYHAVTDNPIHADFQRVSMKDKMDVVVPLKLEGTPADVANYGAIIEHILREIEVRALVSAIPHEIVLDITPMTINKGLVAGDIKLPEGVELITDAEAPVVHLAIPKEEEAPAPAPAADAAAAQPESSSTKGKKDEEGNLTKDAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIY0</accession>
    <name>A0A1Y4DIY0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">B5F75_03380</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56898">
        <property type="protein sequence ID" value="OUO56898"/>
        <property type="gene ID" value="B5F75_03380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="114"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="376" mass="41378" checksum="AB245D07B78581D9" modified="2017-08-30" version="1">MLLSVIAVIVVLSPIVIVHEFGHYIACRLTGIRVNEFSFGFGKILWHKKVGDTDYQVRAIPFGGFVEPAGPMFHPQDAPEPPKPYEFAAKKWYAKFFMVVNGALFNYLLAALIFGVLIYIKGMPETDPVKLPAAVGTVAKGYPAEKLDLQPGDVIRQINGQPIANWKDLTQAMALRKGDVTLSYERDGQTLTATAKAADFKPEAPTVLGITVNPTFKPVSIWAAAGLGFYQCYYWTDFSLRSLAQSFTKKKAPELAGPIGIVNVIHQSVHRSLFDFVFLIAMLSLAVGMFNLFPIPILDGGYALVYLWEGLTKKLPTEKMLNRAANVGLYILLLLVVYASYSDIKRIFFKPKAAAVATQAQAEKGTPSAEAEHVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ61</accession>
    <name>A0A1Y4DJ61_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57709">
        <property type="protein sequence ID" value="OUO57709"/>
        <property type="gene ID" value="B5F75_00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="74" mass="8243" checksum="494991C8CBCF42D8" modified="2017-08-30" version="1">MESYLKVKVHAGEKKNRLEQKGPDSYEIWVKAPAEQGRANEAVRTLLAQHLGVAENKLSLIKGATSPAKIFLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJ82</accession>
    <name>A0A1Y4DJ82_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma carbonic anhydrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57008">
        <property type="protein sequence ID" value="OUO57008"/>
        <property type="gene ID" value="B5F75_03945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="171" mass="18103" checksum="80485F57CFADF47B" modified="2017-08-30" version="1">MRERINEQVPSVRASCYLHKTSVLIGDVTLGENVSVWPCAVLRGDIAPITVGDNSNIQENACLHVNYGAPCILGRGVSVGHGAVVHGSKIGDNCLIGMNAVVMESEIGPNCIIGAGAVVPAGKNIPAGSLVMGVPAKIVRKLEEDEVNAVMRNAREYAEAILLYKDHCEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJC7</accession>
    <name>A0A1Y4DJC7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56430">
        <property type="protein sequence ID" value="OUO56430"/>
        <property type="gene ID" value="B5F75_04340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="254"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="486" mass="52587" checksum="18972ED89A0BB1B2" modified="2017-08-30" version="1">MENKRFIVAIDLGTSGVRAFAVGPEGTVQAQRSAALAPARPQEGLSEYEVDTLLQTQKRVLDDLLDDIGPQRVLALAVTCQRSTVVLWDKKTARPLAPVLTWEDGRAYAQAQRAEISQEEVHTLTGLYKTPYFSAPKITWCLQNIPAVRQAAQAGTLAAAPVASYLIWHLTNGKTFAADATLAQRMLLWDLHTQNWSDKLCRAFSVPREILPQLKPSVGDYGAYAYKGVSIPIRACMGDQQASVAFMDISPEQACINYGTGAFFLYNTGVQKPVLLPGMLTSVSASPADGKASFLLEGPVNAAGSVLQWLQAQGIAFDAPETEALCQTARNPVWFFPALGGLGAPYWDFALSPVAAGLSPRTRKADWVAGAVRSIAFLMTDIAAYVQKNGFKILSPLKASGGLSQVQWLLQQQADLLQKEITPLQEAESTVLGAARLAAAGSGVDTRAWRPKTDEKIYPAVSSAESGALYRKWNAFADWCKKNPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJF1</accession>
    <name>A0A1Y4DJF1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_04455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56450">
        <property type="protein sequence ID" value="OUO56450"/>
        <property type="gene ID" value="B5F75_04455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="31"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="134"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="200" mass="23318" checksum="BEF23C328C4A440C" modified="2017-08-30" version="1">MNMDPKINERTDDELVLLFKSGSSDAFEELVYRYKNSLYQYIMAMVQDEGAAGDLFQEVFISLFKHADKYEPRGKFKSWLFLTARNRVLNFFRDRDKLASLDQTDEEGNAFLHDTLPDGQPSLLEELAGRETEEEIRRASLELPARQREMLYLRQYMSFKEIAQLLDRPLGTVLADCHRAVKKMQRILAEEQPAAREVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJF4</accession>
    <name>A0A1Y4DJF4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57068">
        <property type="protein sequence ID" value="OUO57068"/>
        <property type="gene ID" value="B5F75_04265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="73" mass="8014" checksum="714A22CA8F957525" modified="2017-08-30" version="1">MKFIVALQNRMEALKAQALGCLKKKEGQNTIEYVLMLVVVVGVAGLAGVLIKKFMPDLFEQVKGKITGSMNEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJG7</accession>
    <name>A0A1Y4DJG7_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_03985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57078">
        <property type="protein sequence ID" value="OUO57078"/>
        <property type="gene ID" value="B5F75_03985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="167" mass="17932" checksum="3FB1629635A06D8F" modified="2017-08-30" version="1">MNKGFTLIELLVVVLIIGILSAVALPQYTTAVEKARATEALTLMSAIRQSAERYQLQKDVWPTSNNFSVLDIEVPKVPGSTTQYGGKNFTITMAPTGGNKYFVINALRNITKGKYALKTVLTVETDGTISAKRFCGTNTGLGIGYSAPTGDAEKFCSAITSGHNDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJM5</accession>
    <name>A0A1Y4DJM5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_04880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56530">
        <property type="protein sequence ID" value="OUO56530"/>
        <property type="gene ID" value="B5F75_04880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="87"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="291" mass="31865" checksum="D164BE567EBFD843" modified="2017-08-30" version="1">MLNDRILKRIYTNKTSLFGLIIVVFFLLVALFAPVLAPVQNSNNPYQLPQKSYQIAPQPPSAQNWFGTTEQQYDLYYGVVWGTRLAFKIGLTVTFFAFLIGLFVGGVAAYFGGKTDEILMRLTDIVFAVPSLVLAMVIAAMLGPDIKNMMIALTAVAWPSYARLVRGDILSVKQRDYVTAARTLGARGPRILLRHILPNAIYPSVVVASLDIGYVVLTAASLSFLGLGAQPGTADWGQLIAMARNWVLGTPGHPFAYWYTVAAPGGAIFMFVLGWNLLGDAFRDILDPRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DK04</accession>
    <name>A0A1Y4DK04_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56660">
        <property type="protein sequence ID" value="OUO56660"/>
        <property type="gene ID" value="B5F75_05570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="230" mass="26101" checksum="41FF3B4C9BA11595" modified="2017-08-30" version="1">MRTILPQDFTIVFFPANFITEARVFDLATKIKQQVAPAKLQVNNMVSLPDGMPAPFPFITASLSAGWKVTITANRVDCILQQFNLTGKDLPDSFFDSLVPLFTALSSLFPINRIGAVGRYQDISENGYEELSKKFFVPHLQDKQEKLNSLGFYAKREKDCLSFFDNFQFVRKTINKDGKNIDSFSITRDLNTGKQENNFTENTMLFFFQTARSLLSISQIEEVIYGSNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKE4</accession>
    <name>A0A1Y4DKE4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_07250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000011">
        <property type="protein sequence ID" value="OUO55901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO55901">
        <property type="protein sequence ID" value="OUO55901"/>
        <property type="gene ID" value="B5F75_07250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO55901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="218" mass="23119" checksum="99D429E6F214234C" modified="2017-08-30" version="1" fragment="single">MSLDPLKLTDIVATGLNKKSTAYASINYVPTEAAKVYWEIYTPGTSFNGAATSSNLVTDSSTPTGTGPTPVGGTLVYRSEEDRTARMNFTSKWDGLCGIQGGCTRTYAFNEKMSDGTTCAETGGCTQTFNYGAPMPDGNYVYVLWAEIPYNGKYLNAVGGNGTPSFTANTTCSGQNNEINGQCFTGVKTQNYSVGQIAIERGLVDITIQPVSYSTVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKV4</accession>
    <name>A0A1Y4DKV4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_01940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57558">
        <property type="protein sequence ID" value="OUO57558"/>
        <property type="gene ID" value="B5F75_01940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="236" mass="26831" checksum="BE15FA0C696317AD" modified="2017-08-30" version="1">MTSIYTDGTYLQANPGWHAQDARWKLQHVLRALEQAGVTGKLHNVCDVGCGAGELLKEWARKRPHMHFTGCDISPQAHQLCLQGAPDNVHFVQGNKTGQASFDAVLAIDVLEHVPEPDLFLTHLESKAPLLVLHVPLDLSVRSVIKPEILETERRTVGHIHFYTAPYLRRVLRNRGYQILSWHYTNKYVECPPPLPRLRSRIGMLIRKVAHVLLPHSWAAWWVGGYSVMLVARVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKW1</accession>
    <name>A0A1Y4DKW1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PTS EIIB type-4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57568">
        <property type="protein sequence ID" value="OUO57568"/>
        <property type="gene ID" value="B5F75_01995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.35.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004720">
        <property type="entry name" value="PTS_IIB_sorbose-sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036667">
        <property type="entry name" value="PTS_IIB_sorbose-sp_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03830">
        <property type="entry name" value="PTSIIB_sorb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52728">
        <property type="entry name" value="SSF52728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51101">
        <property type="entry name" value="PTS_EIIB_TYPE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIB type-4" evidence="8">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="155" mass="17651" checksum="A75F64131BDDDB7D" modified="2017-08-30" version="1">MPIIFARVDDRLIHGQIVQAWLPELNVDEILIPCTKGKESCLNRGLLRLSLPYEYELTILNSHDCARYAAQSKRRIFLLMSSLQEFTDLIEDGLQIKSLNIGGMHFKEGAQKLDENVFLDDKDKHFLKLIRDLGINIETRAVPNSQSISVNEAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL37</accession>
    <name>A0A1Y4DL37_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">B5F75_02355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57638">
        <property type="protein sequence ID" value="OUO57638"/>
        <property type="gene ID" value="B5F75_02355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO57638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="198" mass="21872" checksum="657B7B3A16A993A1" modified="2017-08-30" version="1">MNTLSQEFIQKARRLKLLLTDVDGVMTNGTLSFFTDEKGVAREIKNFESLDGMGLLFLAYCGIQTGIVSKGASNTLEFWAKELGMNYLFYNTSVKHHALEFLQKEYGILPEETAFIGDDLIDLGLLSRVGLPLAVANSVPEAKALALYTSPRHGGAAAVRDIAEQILRARGAWEQVVQDNISGRFQNPKRPLRIVKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL57</accession>
    <name>A0A1Y4DL57_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56151">
        <property type="protein sequence ID" value="OUO56151"/>
        <property type="gene ID" value="B5F75_05900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012599056" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="48"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="213" mass="24087" checksum="B9417F21D8EBE37D" modified="2017-08-30" version="1">MKKYLLLFSLILLHTLSFAYQSGDKTLGISLNTAIPCLGSDWGEFNVVNVTTGIEHDAKLGDPSLGFNIHGFYFLSRRIALGLSFGYDYFPTDRASGLELNVNTKSLHYMLLSRIYLNPQNSLQFYLPLGLGIANTRTSIEMGKTEHFQNTNWAASIGLGMEYMVSTHIGLNVEARYNYNRFKTSKFTAQQEYVKLFPQASYISYSAGLFYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL69</accession>
    <name>A0A1Y4DL69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57040">
        <property type="protein sequence ID" value="OUO57040"/>
        <property type="gene ID" value="B5F75_04120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="440" mass="49239" checksum="83F1EE882B0EE78A" modified="2017-08-30" version="1">MKKQPSDWLITIPYHPRLAQRQIHPQLETHRFCVLVTHRQLGKTVCAVNHLLKKALQNTRPHSRYFYLAPFLKQAKMIAWDYLKRYSAPLPGVGVNEAELCLRLPNGARIWVCGADNPDALRGTYADGVVLDEYAQIKPDVFTEIIRPMLLSREGWAVFMGTPKGQNAFFELFNRAQKAAQEEPGVWWVGVFRADESGVISPGELERLRRETPANIFRQEYLCDFTASAENVLIPIDCVLQACARRYAPAEVRFAPKIIGIDPARFGNDRSVIFLRQGLKTWEPLVFRQLDNMALAERAARQIETFHPDAVFVDAGCGGGVIDRLRQLGFSVTEVPFGGAPARPGQYANKRAEMWGEMAAWIKAGGALPECAELKADLCQVCYDFDAAGRLRLEPKEKIKERCGKSPDTADALALTFAAPVRARSAGGKCEFANSEYEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLJ9</accession>
    <name>A0A1Y4DLJ9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56281">
        <property type="protein sequence ID" value="OUO56281"/>
        <property type="gene ID" value="B5F75_06600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="52"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="3">
        <location>
            <begin position="391"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="488" mass="56431" checksum="E8BD5CFDB11EC27D" modified="2017-08-30" version="1">MSNPMQDAPDLSALLRKFKEYNPNQDTSLIEKAYHFAEKAHEGQKRESGEPYFTHCCHVANILMDFNLDADTICAGLLHDTVEDTPVTLEDLRREFNKEIAHMVQGVTKISDLKFSSTDEETVENWRKMLIAVAEDVRVILIKLADRTHNMRTMDVMPPDRQKFKAYETISLYAPLAQRLGMFTIKTDLEDLSFKYLHPQEYASIKNQVEARTADRQAALDAFKKQLEPALQAEHMDFRILARAKNYYSIYRKMQKHHCSFAEIQDSLGVRIITKTVQDCYRALGLVHSVFKPIAGTFTDYIATPKANMYQSIHTTVLAPTGDIIEIQIRTEDMHRTCEYGIAAHWRYKMGNVKPDKNFDEKINWIRRWIEWQQDLTAPREFLEGFKTDVNLQQIFVFTPRADVKSLPEGSTPIDFAYAIHTDIGDHYVGAKVNNRMVRMDYAFKTGDVCEIITRKNGEPKRDWLEFAKTAGARSHIKRYLRSKGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLL0</accession>
    <name>A0A1Y4DLL0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="6" type="ORF">B5F75_06655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56291">
        <property type="protein sequence ID" value="OUO56291"/>
        <property type="gene ID" value="B5F75_06655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="357" mass="39358" checksum="9A8B21B2D77CFD38" modified="2017-08-30" version="1">MEIGIVGLPNVGKSTLFNALTCAGAEASNYPFCTIEPNVGIVPIPDKRLDKLFEMFKPPKKTAAFIKFVDIAGIVKGASQGEGLGNKFLANIREVDAIIHVVRLFEDENVTHVMNSVDPLRDIEIINTELMLADLETATKVCDRLASNAKSGKKDAVAAWERMKEIKAALENGKPVSSLGLEKEELKDYQFLTAKPVLYVGNNSEKRNVQNAEKVANYARENGAGFVELCVKFEADIAEFSEEEKKAFLAETGNDYTGLEKIVREGMKLLNLCTYFTAGEEVEVRSWLIPVGCTAPQAAGKIHSDFEKGFIRADVYTFDDLVKYGSEKALREHGLIRSEGKDYIVKDGDVCLFKVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLN2</accession>
    <name>A0A1Y4DLN2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57210">
        <property type="protein sequence ID" value="OUO57210"/>
        <property type="gene ID" value="B5F75_00055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="253" mass="29501" checksum="225B5D926FAB7F74" modified="2017-08-30" version="1">MLAPAPINVHINVFEGPMDLLLHLIKKDNLDICDINIAEITKQYLDYLNVMKELNLEVAGEFLVMASTLMQIKAKTLLPSQAPTTEDEGPNPVKELVAKLVEYQKYKEASKFLEQKFEENKDNFYRSAPIFDDGEKVINLQMFDLLSAVKRAFERLDERKRIELLKVEEFPIEMKMEKVVNLLKHREWVLLDDIFVGETKKRGIITCFMAVLELMKIKKLIARQDEKLGQIRIYLNPENKDKDFKTLMHGEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLS4</accession>
    <name>A0A1Y4DLS4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">B5F75_06925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56341">
        <property type="protein sequence ID" value="OUO56341"/>
        <property type="gene ID" value="B5F75_06925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="122" mass="13513" checksum="FF09A7EAF37923B4" modified="2017-08-30" version="1">MIQLRSIVNVADNSGARKVQCFKVRGGHHRDIATLGDVVMCSVRDAIPTSAIKKGDVVRAVVVRVAREKRRKDGSYIRFDDNAVCIINDNGEPKGTRVFGPIARELREKNFLKIISLAPEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLY3</accession>
    <name>A0A1Y4DLY3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57310">
        <property type="protein sequence ID" value="OUO57310"/>
        <property type="gene ID" value="B5F75_00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012825076" evidence="2">
        <location>
            <begin position="30"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="450" mass="51262" checksum="60FE06C5478388BA" modified="2017-08-30" version="1">MHKLLGCIFCLFCASAAAGLSFSAQTALAGSVSPQQQDFTLQQYIALYLNYSPQLQTETNKLKIEHNTYKNAFTTAFLPSFSLGVSASETYGRNYHFSSWEDFQHGDSYGQAQGSWNLFNSGKDVLNYKMASLDWQIAQINYDSTVQQYVLEAVQTYYNLLLSQKLLQVYEDDLAVAKKQYEQDSILYENGLKTRSDLLSSDTNWRSSQLSLFSAQNDYANALKNFNIAINRPIEAPARLDENIPQDLPALPPLDQDLTTAIAHRYDARTRRLSLKQSDITQTLGNLNTLPSVFVDLFANTGRGFSTHEKWDYNYGISAGISFDIGFLYFNKYRERKNVRLTNQNAHLEYEQFLRSLRDDVVETRNTLSLKMRSLEISKLRLQAATEKFDATQLKYKNGLMGATDLTVARQELISAQVDYATLLSELTLSRLRYQYALGEQLYDYKPEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM25</accession>
    <name>A0A1Y4DM25_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57340">
        <property type="protein sequence ID" value="OUO57340"/>
        <property type="gene ID" value="B5F75_00770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="184" mass="20565" checksum="E22F50706DA9B543" modified="2017-08-30" version="1">MKKGFTLLELLVTVIIVAILSSVAVMYYGRFIERMRIAEADTAIGSAILSQERVFIKFQRYTPYWHQLDAGPLAVRTPKENNDFANGKLNTIYYTRGGMLSGKPKSGFAISFETDATGRWFAVARRVGDDTYTYRIVRPFDDTKSTCVPDWGNEKDLAICVDYMGVADAAQLSPDPMVPKVEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM48</accession>
    <name>A0A1Y4DM48_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56471">
        <property type="protein sequence ID" value="OUO56471"/>
        <property type="gene ID" value="B5F75_04565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="205" mass="23702" checksum="40F3D1188D5A7DF4" modified="2017-08-30" version="1">MFLPKEVKFFDLFDKQAENIVRAAAFYKKLVDNGDFTPENVREMHELEHYGDELTHTTINTLNETFITPFDREDILALANRLDDIVDGIYLISNRFHLYKIQKPTEFSRKLAATIESTTKALQKALASLRSNKNMKETLHQCVEINRLENEGDVLRDEAISSLFENEKDPLMVIKHKELYELAELVTDSCEHVANLVESILVKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM87</accession>
    <name>A0A1Y4DM87_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56511">
        <property type="protein sequence ID" value="OUO56511"/>
        <property type="gene ID" value="B5F75_04770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="144"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="40526" checksum="FAAE211DF1A3D41E" modified="2017-08-30" version="1">MKTIRTAVIGFGFMGKTHTCAYQALPFFYEPPFTVQLAAVCARTYEHAQAACQRYGFERAARNIDDILALPDIDVIDICTPNALHAPAILKALDAKKHIYCEKPVACGPAETRRILAHPNLNKVITQTVFNNRFFPAAKLAKQFMQENRLGKILSFRARMISPSHVNAATPIRWRQTRQTAGGGVLYDLGAHIMDLLTWLAGPVKSVYTKTQTAYAQRPDGKGGLADVDTDDAAYAVVTLANGAVGTAEASKLASGTNTDLYIEIHGDKGALKIDFMDANWLYFYDAAAPYKGYTRIETVQNYAQAHPFPPVRHPLGWLRGHVDALYEFLCAVAQNRPASPSLAEGLYVQSVLDAMYQSALENKEIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMC8</accession>
    <name>A0A1Y4DMC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57450">
        <property type="protein sequence ID" value="OUO57450"/>
        <property type="gene ID" value="B5F75_01370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012689319" evidence="1">
        <location>
            <begin position="22"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="294" mass="33280" checksum="2B25CA7BA71346AF" modified="2017-08-30" version="1">MKDMKKFILFFMLLAFPAALPARTVDVAAAYIGASHFDQVRVAATMAPTLNLLTGIEAQTIHERAFEDPIYSVGVPIHLDFDLLQFNITPFYYFKNKSDNPDYQDASAYGVTARMIIALEDDQVNDLYTHAVLGVSYANQQGTVFREGGEFSNTDYAQMVYTLQLHKNFFRMFGFEAAANVFQYPDGITGVTGLRSILNQQDLAFTQTFDVTHDLAKYTLGARITRMWPDNAATLYVGYRYGEYYTADPEHSFIVGNSFAATRNISADIAYNHVRTIHNDNKRDILYARMIMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMM0</accession>
    <name>A0A1Y4DMM0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Lysozyme</fullName>
            <ecNumber evidence="2 6">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of (1-&gt;4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.</text>
            <dbReference type="EC" id="3.2.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="2 6"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56641">
        <property type="protein sequence ID" value="OUO56641"/>
        <property type="gene ID" value="B5F75_05475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002196">
        <property type="entry name" value="Glyco_hydro_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023347">
        <property type="entry name" value="Lysozyme_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00959">
        <property type="entry name" value="Phage_lysozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="4 6" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="138" mass="15591" checksum="A311BCA9D0D03E04" modified="2017-08-30" version="1">MDYEKLAARIRKNEGLSHRPYRCSAGALTIGYGHNLDARGISKEVAELLLKQDLEIAEKQVKNAFIWWPKMDDARLGVLIEMCYNLGLLGLVGFKKMLAAVEAGDYKRAAKEMLDSKWAFQVKGRAVELSKIMETGEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DMU3</accession>
    <name>A0A1Y4DMU3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_02370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57640">
        <property type="protein sequence ID" value="OUO57640"/>
        <property type="gene ID" value="B5F75_02370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="209" mass="22792" checksum="3261D4B93D691D09" modified="2017-08-30" version="1">MDDIFIKIFLALVLGGALGLERQYHDKPAGFATNCLICLGAMLFTVLSEVMGEAGGDPGRIAAQIVTGVGFIGAGSILRDGNKISGLTTAAGVWLVAAIGMAVGYGQYFWAALCAVAILIVQLAVRKTLKLVEFVKHYDTFYLTCEPRWSVVDKIIKQIEAQNISILKSEVTKQDNRFHVSLVATFTGHDFQNITKELLEMPEVYSLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN10</accession>
    <name>A0A1Y4DN10_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56791">
        <property type="protein sequence ID" value="OUO56791"/>
        <property type="gene ID" value="B5F75_02805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="8"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="391" mass="42058" checksum="825C3C89B6831E90" modified="2017-08-30" version="1">MKFDCYLPTKILFGAGRLNDLATAKLPGKKALIVISAGTSMRKYGYLERVQKLLAQQGVESVVFDKILPNPILAHVTEGAELARKEGCDFVIGLGGGSSIDSSKSIAVMAKNPGNYWDYISAGSGKGKFPKEGALPIVAITTTAGTGTEADPWTVITNGPEKIGTGWDFTFPTLSIVDPELMTSVPPHLTAYQGFDTLFHCTEGYIANIATPVSDALALKAIELIAKYLPRAVKDGNDLEARANVALANTLGGMVETFSSCTSEHSLEHALSAYYPKLPHGAGLIMISLPYYKFFLGKVADERYANMAQAMGEDVRSLPAEKRAQAFIAALEKLQKACGVDNLKMSDYGVKADEMDKLATTAKETMGGLFTLDVHSLTHEEAIQIMKEAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN70</accession>
    <name>A0A1Y4DN70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">B5F75_03120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56851">
        <property type="protein sequence ID" value="OUO56851"/>
        <property type="gene ID" value="B5F75_03120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="31"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="112"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="312"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="447" mass="48818" checksum="B3AA9F0CFBADFCD6" modified="2017-08-30" version="1">MKLNLTVSKIAQITHAELVSSHPQAVVTSFVTDSRVIRPGDAFLALKGKNHDARQFIPQVLQKGASVVLAEKGFALPAGSDVSFILVDDSLKALQALAKYHRLNSTLKVAAITGSNGKSTTKQMLRAICETAGETIANMGNFNNQFGVPFSLLEIQPKHQYGVFELGASHPGDIREIASLAVPDVAVITNVSAAHLEFFHDLETVYKTKTEIAECLNSGGTLVYNADDPLLARLKTQYKGKSLSFGFHPGADLQILETEKFSFTYKGEAYVLDIMLQRHDKLNAAAAAAAAIALGLYMDNVKKGLLSYTPMPMRMERLQKDGVEFILDCYNANPASMQNALEILGRETATPRIAVLGDMKELGETSKEYHRLIARQLQDNGVEYAFLAGPEMKYAYDKLKDVPGIHAFYSLTPSGWTKELSAALKKGGTCLVKASRAMNFENILKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNC6</accession>
    <name>A0A1Y4DNC6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56901">
        <property type="protein sequence ID" value="OUO56901"/>
        <property type="gene ID" value="B5F75_03395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="174" mass="19048" checksum="694C45BD142C8D2A" modified="2017-08-30" version="1">MNKIYQKSSPGAKNAGFTLIELLVVVLIIGILAAVALPQYEKAVFKARMSEAFVNLKNLARAIQVCELTNGGPPAGQWSTYPCYDTSALDIELGTPDSYFFNTEQFTYIIDRGSLTDPDVLAVGYHKLSDVCICIDEEGNFFADQEPAGCGNGNYPKFNVPKTLNIEDRVCNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPY3</accession>
    <name>A0A1Y4DPY3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Na_H_Exchanger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57431">
        <property type="protein sequence ID" value="OUO57431"/>
        <property type="gene ID" value="B5F75_01270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="6">
        <location>
            <begin position="6"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="411"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="434" mass="46466" checksum="801FFD831081E1B1" modified="2017-08-30" version="1">MTYAILFIGVLLFLGHIFSSLFEKTRLPDVLPLMILGILMGPILHVVSPASFGEAGQIFTTLALIVVLFKSGLDFRILSLRGAVGQGLLLTTVCFLLITALIAFITQWTLGIPQIYALIIGAIVADNSTAIITPMLAKLKVSKTTKTILFLEANLTGVYSIVLALALLSAASRGGTVSAGALAAGIIKSFGIGIVFALAAGFFWMSILNRVRRLENAISLTFAFVLLVYSVSGLIGGDGAIATLAFGVVAGNIRLIKRLWLPKLDYRRLLSLNSGEKDFFDEIEFIFKTLFFVYMGICIRLGRMDLLAIGLLLALAKLVFRAPVVNYCVSKKITRSDCSVITAMCPNGLVSAVLAAMIASQLPQEGAVIQDVIYAVIFFSVVLSNLMSFRIEKGGLQWLGKAMFFRHAQGTGAPAPAQPEQGAAPAAENPPTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-06-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPZ6</accession>
    <name>A0A1Y4DPZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="10" type="ORF">B5F75_01325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57441">
        <property type="protein sequence ID" value="OUO57441"/>
        <property type="gene ID" value="B5F75_01325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="442"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="509"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="634"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="660"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="730"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="759"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="787" mass="82554" checksum="29D5E9DF4FDFD04C" modified="2017-08-30" version="1">MWYGIASLRPFEQYALFGVLFIAVLGLLYALFLRKQVIREDAGTPEMQKVWGAIREGANAYLKRQLKTILPLIGLLTVCLFLSVYIVPVSQDSMERFAGLSAGTVKLIAAFGRAGAFVLGAVFSLLVGQLGMRIAVDANVRVAAASKRSFGDALRIAYRAGTVTGMLTDGLGLLGGTVIFVIFGIAAPDALLGFGFGGTLLALFMRVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPAVVADLVGDNVGDCAGMAADIFESYEVTIVSGLILGIGLWRITGHHEWIVYPLLVRGIGVLCSIIGTYAVKDSKRTAGNAMKAIFKGYSISATISVVIFGVLAYYYMSAVPGGWWRPFAATTIGILLAIIIDRLTEYFTGTENKPVQEIKKSTATGSATTILSGIAVGFESAVWTTLVIAASIFCSVVIFGTIDGLTPSEKFNFILYGVAMTGIGMLTLTGNNVAMDSFGPIADNANGIGEMAWHGQDDAETKKARQIMADLDGVGNTTKAITKGVAIGSAVIAAVSLFASYMVDVSNVQRLLNDAWAAAGEAKVLTLLSQVGIVVSNPVVFVGMLIGAALPWLFSSFAINAVSRAAALIVQEVRRQFKGGVLEGTAKPDYTRAVNISTIAAQKELIILALLGIVSPVVVGLAFGVEALGGFLAGIIVSGQLLAVFMSNAGGAWDNAKKVVEDEPTDIAANTGKGSERHKASVVGDTVGDPLKDTAGPAVNPLIKVVNMVAVIVAPIIVNYHNDFTPLGKIGWVIVIFLLAVLSWAILTSKKPAQDLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQA1</accession>
    <name>A0A1Y4DQA1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS</name>
        <name evidence="11" type="ORF">B5F75_01845</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57541">
        <property type="protein sequence ID" value="OUO57541"/>
        <property type="gene ID" value="B5F75_01845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="10">
        <location>
            <begin position="686"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="488"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="612"/>
            <end position="619"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="854" mass="94499" checksum="193A1242436E4790" modified="2017-08-30" version="1">MPKTTTTPLMKQYYDIRAQYPGIVLFFRLGDFYEMFDEQAREVSALLGLTLTARNGTPMCGIPYHAANNYIVRLLNAGKKIGICEQTSSVMDKNTKLFERKVIRVITPGTLMEDTLLDANQSNYLVALSAGANGWALSCVEVSTGEFWINQNDKDPTLTNLAAALAAINPSEIIGDKDSLALLKTKVVLPGNLTLTERPAFDGDYTLPDNWPSLSAWGNKRKALACALQTMDYLNVTEPSFKTVLIPSYRELKECLQIDENAVASLELVKSQEGGRKGSLWALLDKTKTAVGSRKLKEWILHPLMDPGEIAQRQDCVEGFAKNPAAVADLTALLENISDIERIMTRTATGTASPRDLSGLRQSLLNVDPIARWFETYGAAIAPHLQAKFTEILPVLQNMARVLYDAIDENPPLRLSDGHVIRRGYNAELDELRSLKSNGSKSMEEICAREREKTGISTMKVGYNSVFGYYFEVTKSHIDKVPYSYVRKQTLVNAERFITEELKELEDKILNAEQKILRLESALFDAVRKTLAAQINNLKDFAHIVSELDVYVSLALCALQGGWVKPVVDNSTELHYQNGRHPLVEATLPAGSFVPNSLDIGTPQNQIMLITGPNMGGKSVFLKQTAILVILAQMGSFVPASSARVGIVDKIMTRIGAHDALSRGNSTFMVEMNETAHILASKTPRSLILLDEVGRGTSTFDGISIAWAIVEYLYQPHGGPKVLFATHYFELVDLENKYESVRNYHVEAKEYKDACGASRLAFLYQILPGPADRSYGIHVAEIAGLPAACTLRAKKVLKDLEAKKGAKISAKEQDMVKDLFSSPIVEEIKMADPDKLTPLAALQLICEWKKRINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQB7</accession>
    <name>A0A1Y4DQB7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallophos_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57561">
        <property type="protein sequence ID" value="OUO57561"/>
        <property type="gene ID" value="B5F75_01960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="245" mass="27681" checksum="3F78FC25776DB955" modified="2017-08-30" version="1">MLVGVFSDVHSNLEALDACLERYQKEGVSHFIYCGDIIGYGPDPEACVRKISQLNLLACVLGNHDAVFVQPELESLFNYDAKVALDANKKQLSEKSIRFLSALPTVRHGDNFTAVHGTPADPIKEYFSSCSQFRACFDLWEGQVCWVGHTHLPFYMKGSPRACAIYLNRKEDALVRLNDKNRYVINPGAVGKPRDNNPHASFGIWDTEAKTFRFIRQPYDLRITQEKMAKQKYPSFLIDSLSLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4D9V6</accession>
    <name>A0A1Y4D9V6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56037">
        <property type="protein sequence ID" value="OUO56037"/>
        <property type="gene ID" value="B5F75_07090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="37"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="451"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="664" mass="71990" checksum="07B079E4C44FCC02" modified="2017-08-30" version="1">MKIPPTALKRLRHIAGAENVLTDELSLSLYAYDCSLSRTRPDAVIHITREEMVSPVLKTLYQYKIPFVPRASATNHAGSCTALNGGVILNLTALKHILQINTREGWAWVQPGVITGDLQDRLAPLGYFYAPDPASERVCTVGGNLAQNASGARCMKYGGTIDHVLAAEVVLADGTPVSVSRRQGGPDWIGLLAGSEGTLGVITRLQVRILPAAKHIKTFLVTFPSLADSVQTVSDLVARGIIPRCVEAMDQITTRAVEEFAHAGYPLDAQALLILELDGKPAQIEKEEKELEEICLKNKAQHFIPARTEAERQKLWFGRRAAYAAMARLAPNVMVGDGTVPRSELPRALKKVRQILDDNHIVASLLFHAGDGNFHPQIVFDERNKPETVHVTRALKEILQACVDCGGTVSGEHGVGVEKRAVMAYQYDKPTLDLFRQIKQALDPRQLANPLKLIPVNYAEKARPAAAPDARMAALASAVLRRKEAQAPCIPIGQNTRLQTTAQNTLSTQTLARVIEIDKTNYTATAEAGVPLAALVQTLQQEQVFCALPAGKGSLGGAFCSGCMPDFYSHVLGLEALLPDGSFVRYGGKLMKNAAGYHLTRLFAGSQGTLGIVTRLTFKIFAQPVASVPVLPFVQAPANALWRAIKKQLDPNDLFPALKGEEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA53</accession>
    <name>A0A1Y4DA53_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56137">
        <property type="protein sequence ID" value="OUO56137"/>
        <property type="gene ID" value="B5F75_05820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="51"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="124" mass="13333" checksum="8A9BDAE36037B957" modified="2017-08-30" version="1">MDTKLITEVTDWLKTTDLAEFCYAKDGESIEVKTAEALPEPAHFSCSLTAVAAPAIGIYHAADKGKNLVLKEGQSVQEGDVLGVVETFSKKHKITAPVSGKLRVVTAQEGAPVEFGLPLFFIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DA63</accession>
    <name>A0A1Y4DA63_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_05855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56144">
        <property type="protein sequence ID" value="OUO56144"/>
        <property type="gene ID" value="B5F75_05855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="401" mass="45530" checksum="A8A434C1EEE61981" modified="2017-08-30" version="1">MFFTKVQTEKYADVMIWALETARRNGKFKPYDTVLLRSDLSALPLARALYTKLLARHYQVIMRFNAPEDFSKTFYQHADDKQLAFIAPGEKEFQGGINGLISLRAPEDLTHLKQVDPARIAKSAVARKPLREILDVREQKGLFSWTLCNYPTEELAKRAGLSVKEYASQVARACFLNEKDPVKKWQEVTRQITEIGKWLSSLPIQTLRVETKNMDFEVLLGEKRKFIAGGGCNVPSFEIFTSPDWRGTRGVYFADLSSYRSGNYVKGVRLEFEKGRAVKADAQQGAEFVRKMLAMDKGAAQIGEFSLTDRRFSKITKFMADILYDENFGGKYGNCHVAVGSSYADTFSGAQSKLDKKTKEKLGFNDSSLHWDLINTENKTVTARLKDGSSQVIYEKGQFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAG1</accession>
    <name>A0A1Y4DAG1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">B5F75_06255</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56217">
        <property type="protein sequence ID" value="OUO56217"/>
        <property type="gene ID" value="B5F75_06255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="157" mass="17471" checksum="A8EE45D58C7726AB" modified="2017-08-30" version="1">MGEPFYVSRKKYEALVNELKDLKNLKAELSNEIGEAAAQGDLKENAEYHAAKEKQTETLIRIQELEIRLRNAQITDDLTVDKSEARIGATVTIRDEAAGIEFTYTLVGSMESNPEKGLLSVKSPLANGVLGKKEGETFEAILPKGPKKYKLVKLEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAK1</accession>
    <name>A0A1Y4DAK1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lpxC</name>
        <name evidence="13" type="ORF">B5F75_06340</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56233">
        <property type="protein sequence ID" value="OUO56233"/>
        <property type="gene ID" value="B5F75_06340"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="274" mass="29777" checksum="D16DB38B872CF52E" modified="2017-08-30" version="1">MRKTLSSPAVVSGVGLHTGVPATMTFKPADNGITFLRTDIAGAKPIAAHVNSVSSTLRGTNLKNETAEVWTVEHALSALHALGITDAAVEMDGPEPPVTDGASDLYIEALQKAGLKELPAEQPLLNIKQKITYSSGNISYSAEPADKLTFTFLFLHKHPLVSRQEFTLEFTPENYIKEISRARTFGFEEELAFLKAHGLAKGGNLENAVIVGKDKFINELRYPDELVRHKILDLVGDLSLTGRKLPPLKITCACGGHKHNIIFAKILLANSEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAK6</accession>
    <name>A0A1Y4DAK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56243">
        <property type="protein sequence ID" value="OUO56243"/>
        <property type="gene ID" value="B5F75_06390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="314"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="378" mass="40690" checksum="D6BF3D3C299A7379" modified="2017-08-30" version="1">MNASISAAERLARIQLNAFLYFRADWLERLIEIFGSAQEILRQDAQTLAREANLNPSTAAHLLRDAFSIHPQEEWDKTAALGGHIYIPEDEEYPQSLRNIKEAPIALYVLGRLPAPEQACTALVGTRKITPYGRRVAAKLAGDLSACGVTVVSGLARGVDSECHAAAVRLQKPTVGVIGTGVGRCYPPENRALEKAILQHGGAIVSELPFNSPPNAFHFPRRNRIIAALSQPVVVIEGEIKSGALITAKLALEMGKDVLAVPGPIDSPQSAGPNALIRDGAGVVTAVSDILDYIPQQLRFGLDARFFEKKDDSAPKPQEELTPRQREVMNAVGGSQASLDQIAEALGADVPETASLLFELEVKGFLACENGLYSKSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAK7</accession>
    <name>A0A1Y4DAK7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="12" type="ORF">B5F75_06395</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56244">
        <property type="protein sequence ID" value="OUO56244"/>
        <property type="gene ID" value="B5F75_06395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="763" mass="85529" checksum="D0C1B3C5BCBB55F0" modified="2017-08-30" version="1">MATTNPKGKKLVIVESPTKQKTISKILGNDYIVRSSFGHVRDLPSKDIGVDIEHGFKPTYVAVDRAKRLIAELTAAAKNASEIYLATDPDREGEAIAWHLVELLKLPKDRYQRIYFHEITPAAIKESFAHARKIDDNLVNAQQARRILDRIVGYKLSPLLWKKITSGLSAGRVQSVAVRLLAERAKEIAEFKEQEYWTIGAQFEKPGAAPSFWARVTKWQGKNVEQTTTYKLFAEDYKVKTTVFDKPEKLAPLSELLRKGPNTVLKVEKKEVKQKPKPPFITSSMQQDAYNKLGFPSQKTMMTAQHLYEGIDVQGQTVGLITYMRTDSFNVSKLLQEQTKKFIGEKYGPAFVPAKQPVYKSKVMGAQEAHESIHPTDVRRTPQAMKPFLTSDQYKLYELIWLRFVASQMADAVFNTVAIDIASGSKEQCVLRASGRTVKFPGYLSIYKDQEEDSSEEKEDGSALLPILAEGDELKLLDIKTKDHKTTPPPCYNEASLIKTLEKHGIGRPSTYAPTIKTILDRKYIARQPKTSKLVATDLGITVTDSLKDFFKEIMDLSYTAGVEEQLDQVAEGNQQWVKLLSDFYTNFKKELDEAEQGMQRPAAKETDEKCPICGKMMLKKRSRFGEYLVCSDPQCKGKINLTSSGEKVQPEKTDEICDKCGAPMVIRTGRRGKFLACSAYPKCKNTYSLDAQGHKVASTGPIITDRLCEKCGKPMVLRTSKRGEFLGCSGYPKCKTIVTVTPEEIEQIKAAHAAKTAAEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAL8</accession>
    <name>A0A1Y4DAL8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lolD</name>
        <name evidence="5" type="ORF">B5F75_06530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56267">
        <property type="protein sequence ID" value="OUO56267"/>
        <property type="gene ID" value="B5F75_06530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OUO56267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="221" mass="24344" checksum="206633DD6FFA3E9A" modified="2017-08-30" version="1">MIKLEHITKIYGQGDENLCVLEDVTLTLPRGKFTVLLGPSGSGKSTLLNLIAMLDKPTSGTIYLDGQNITALKSETARSALRLKKMGFVFQFDGLLPEFSLLENVDMPALMRGRPDPKKAQQLLENLGLGAISHKLPADLSGGEKQRASIARALRNDPPLLLADEPTGNLDTARKQQVFEDFARMSREQGLTVLMVTHDVHAADYADEVYTLENRKLVKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAN9</accession>
    <name>A0A1Y4DAN9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin-NADP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_06560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="2">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="1">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56273">
        <property type="protein sequence ID" value="OUO56273"/>
        <property type="gene ID" value="B5F75_06560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="64"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="284" mass="30954" checksum="EAD6867E43D940FF" modified="2017-08-30" version="1">MEENTILVKENLSDVVVKFVIYKPLVAASAKAGQFVILRGREGGERVPVTLVDWDKEKGTITIIIQAIGKSTSMFNSFKQGEKFLNIAGPLGTPVEIKNYGTVAVVGGGVGIAEVYPIARAFKEAGNRVIAVLGARTKSLLILEDEMKALCDKTVSTTDDGSYGMKGMVTDAIQKLHDEGEKINAGFIIGPIPMMKFTSRLMDKLGMEPHASLNPIMLDGTGMCGCCRVTVEGKVRFACVDGPMFPSKTIDFDELIRRTSEYRPQEAESLKLYEKDHVCKCGLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAP1</accession>
    <name>A0A1Y4DAP1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56287">
        <property type="protein sequence ID" value="OUO56287"/>
        <property type="gene ID" value="B5F75_06630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="117" mass="12778" checksum="E20A22A28D4930B6" modified="2017-08-30" version="1">MTEEKETAPRAKNTDDYKCGLNGEGCLNSRFTLSIIAVILSCFTGFFTIPIALAALILSLRAQDWARDGRMAEAQRVAWWAGFCGWLTVIIALIPIFLIIFFGGTIIAFLTAMLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DAT4</accession>
    <name>A0A1Y4DAT4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56314">
        <property type="protein sequence ID" value="OUO56314"/>
        <property type="gene ID" value="B5F75_06785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186868" evidence="1">
        <location>
            <begin position="25"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="256" mass="28210" checksum="5909ACAFE254109B" modified="2017-08-30" version="1">MNSNFYTKAVVVFAVLTGFAGWGAAQTVKEMKPALDRAAVQAEKKHRMQTSVVNLNFRWEKEVYLSDFVSRRRPGFKDTFIQRKQKNTSCRGVLVEGGRRVLTPVQCAQAPEGFTLKSVTLLFSNGQKGLGSKRTVSMNGELAEIWVSPQVTKGLKGVPLATVAPGESLADAFGNSVLDELLQFFINRGVVSGRANRITGTKNTLQVGDPFFYQGKVVALVREVPSRLPVSFWGGVSEKPLTLLRTQHQKGLFAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB70</accession>
    <name>A0A1Y4DB70_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AsmA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56306">
        <property type="protein sequence ID" value="OUO56306"/>
        <property type="gene ID" value="B5F75_06740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007844">
        <property type="entry name" value="AsmA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05170">
        <property type="entry name" value="AsmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA" evidence="1">
        <location>
            <begin position="30"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="766" mass="86362" checksum="3653B09348E48F26" modified="2017-08-30" version="1">MSKKKKKKRSFWSWVWRFIKSCVVLSLRTVLFTVMLLLLIAAGLWLLFLKTFNAQHISELITEELQKRLDRPVIISSLDLKFINTVELKGFSVVDTEGAPGYALLSADSVTLQFKLLPLLDQQLIIDEVSLNSPRFNIVRLPDGTYNMPQIRTPKEKSVYTSELTGRKLAVSVEDWSVHNGVLSYKDLASGVSHAIYGLNMHFEQLRFNELSRFQAEMILRNKWGDNISDMEIKGTGHVNFANFDWSKFALRSLRTQVFLFQKPVDLLIDLDNLRTPYFNVKASVPAFASKDLSLFHEKELGFSIPKAQLTAQGKLEQDYRLLTLSQVSVSAADVQAQGSGTLDFTQTPFTADLSAKTNFFKLADKHTYYPDIRQYKLTGQAAVSAQLQRQKGKFSLPLLNVQGKDVSGLFYGFKAENIDGEFQAKQNFSDLYARTTAGKVTVHNSVFDKLDLSASWRKGNLYAYIASTELNKVPFKLSLSVNNLKSARRKIRTSIYWKDLDPLAFIDTVKDFVTVITPLLKKGAKFKEPVEGELAWLRNFRDRLPKFMPNFAGNLTADTFSTQVLSGNRFSAEFDFTGMSAGMKNLSGPLEARLEGGVIHQMEKLAEEQQALNITFQPFILMHRMERAGSFKVGQVLKDVPFNDMAVSVNFDKGRMQINNAYTVGPTISAAVSGWTDWVNENFDIIIWTMFNNTSRSGALAENLTDESGNPALAFRVSSSMLKPKLEMMRAKKTGQTIRTAQEQGLNTSFKAAQEFIQGDFHAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DB75</accession>
    <name>A0A1Y4DB75_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56433">
        <property type="protein sequence ID" value="OUO56433"/>
        <property type="gene ID" value="B5F75_04355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="314" mass="35140" checksum="EE45CF7D331C5DE7" modified="2017-08-30" version="1">MKHILGVLILLCLPLASFGQLSKLGPSVGKALATKQPAAAQAAKVSSKVLKANYLLTNQSIQLFQQIHMQKVANVFADTELEAAVAQSVVEQMQQEAAVSLAALTAKMDKEYAQWADALLRERNPNFLPKKDPSIPGLLAFSPDPKQKIHITPRFFREWAATIPAYEELPEEVAGLIAALRKRLIALETDTFKETRLYMKAKSHLNPVDDFNSNRYYQKQMAKSNRALLNISKESAQCVADLVYLLNLYPSLFKDSLTLLAAKLDHGLQTEFTAYLRRQIDLPPQKENISRPVGFQQDRKQPPVLTGKTFNGFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBP8</accession>
    <name>A0A1Y4DBP8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-deoxyinosine glycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56584">
        <property type="protein sequence ID" value="OUO56584"/>
        <property type="gene ID" value="B5F75_05165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026353">
        <property type="entry name" value="Hypoxan-DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04274">
        <property type="entry name" value="hypoxanDNAglyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="170" mass="19151" checksum="3E08D66BAE06DA30" modified="2017-08-30" version="1">MPKPLHSFPPLADAHTRILIIGSMPGAASLSAHEYYAYPHNQFWRLMFDLLESGRTPANYADKQNTLLAHRIGLWDSLACCERTGSLDSAISRPVPNDFPTLFARFPHIQTLLFNGQAAHRYFKRAFNGFLGKEVFLLPSTSPAHAARSYQEKRACWQNALRAALQEPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR5</accession>
    <name>A0A1Y4DBR5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56593">
        <property type="protein sequence ID" value="OUO56593"/>
        <property type="gene ID" value="B5F75_05215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="318" mass="36430" checksum="0235504CA20172D6" modified="2017-08-30" version="1">MYTPRDVEVFLFAHDRPAFLREALDSYLRQTVGGFRLALLANAPTPEVLQVAKEYAGRGVELILEPQSLNVYGCVRRCQELASRSITVLAHDDDWVHPAYLETLLKCYNRFTKLQVAVSAAGEWDARPFTADYHTQLVLLKRAEFSAYIFTGEPFAFSSSSYKTEFFKTAPAPDFARYGKVNDVPFMLGVCHGGEAAVLQFPFVKCRIHPQQDSLTFATGPRAREWIELDLCHKREMSQGGRKLRWAYILNAFHRLKTGWRDWCVCEHDKMTFKQYLNLARQMGALDAKRRLFGVLLRGGVRKACLEKLCSFVRLELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DBR9</accession>
    <name>A0A1Y4DBR9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56597">
        <property type="protein sequence ID" value="OUO56597"/>
        <property type="gene ID" value="B5F75_05240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="303" mass="33538" checksum="9AA0853569124484" modified="2017-08-30" version="1">MKVLVTGGSGFIGSHTVDGLIERGVETVVVDKKKPSFPNAKALYYQMDINSDGFASVFKAHKIDGIIHLAAQPSVSFSTKNPLEDAQNNIIASIRVIEEAKKNQVQKLVVSSSAALYARPQYFPIDEKHPTAYLSPYAISKHTMEEYVKWSGIPYVIFRYANVYGPRQDSQGEAGVVAIFTDAVTRQEPIFVHGDGNQTRDFVYVKDVARANCQAVLSDVAGETINLSSQTEVSVNELAQMLTSSVPAYQGKIQHIARREGDIYRSVLSNQKAKELLGFKNTYSFAQGIKETVTFFEKQERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC00</accession>
    <name>A0A1Y4DC00_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56667">
        <property type="protein sequence ID" value="OUO56667"/>
        <property type="gene ID" value="B5F75_05605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="277" mass="31443" checksum="148618AEB56D3A56" modified="2017-08-30" version="1">MENKGYVKLHRRFLNSAVRRLKPSAVCTFIDFLLMADYKSGEIRTTYRDLAGCLTVSNQNSIKQVLDCLERAGAIKTQRKPCLIIKIVNWKKYQAADKKEPGETAEKLWKTATKSVAPATESVAGSATKNVAVCYEKCSGDNNKVPVSMYSLKNKEYFLCKSWSTQIDFQNPKTDLEKLALYYLQGTNHPGLKKPNKNEILNAAVRMDIPHFETILANCRDLEQAKACVARYVRRAKGLYSLYYLACQINSIRQEVESEELKNGKFLRPGQRPAEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC16</accession>
    <name>A0A1Y4DC16_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_05690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56112">
        <property type="protein sequence ID" value="OUO56112"/>
        <property type="gene ID" value="B5F75_05690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1617"/>
            <end position="1696"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1739"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1858"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1989"/>
            <end position="2068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2715"/>
            <end position="2734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="3027" mass="327138" checksum="19DE9B0F0F4CAE85" modified="2017-08-30" version="1">MPRKEDFTLGDKMKNKNLEPIAIVGIGAIMPGALNKDEFWSNIKEGKYCITEIPASYWDYRLFYSPDHKAEDKLYSKIGGFIPQSFKFNSLKYRIPPQIAKQMDTVQHLAIETTRMALEDSGYDKKEFDHNRTAVIIGNSMGGMKNEMSNTRLNRPFLYEILKNTPSFKSLAPSDAQKMLEEMDAGVREKFAPINEDSMPGELANVIPGRVANVFDLHGTNFAVDAACATSLAAIDQAVNGLRMGNFDMAIAGGVDQMMSPSAYIKFCKIGALSETGSYPFDARANGFVMAEGAGMVILKRLSDAVKDGDRIYAVIRAVGASSDGKGKGITAPNPKGQKLAVEKTFEQLDYTPEAVGLIEAHGTGTRVGDAVELGALTELFSPYVKPGSIGLGSVKSQIGHAKAAAGIASLIKTSLALYNKVLPPSVNFETPNPIVDWSTCPFRVITKAEEWPGGKIRRANVSAFGFGGTNFHVAMEEMNDSLLKKAEESKQQVTVSVPVQEKPTMTSSNSYTLHVPGEKIQSDVLTFSAATKQELFNVLDKALVAIEYDPTYLPSISYKNHIAKPAKFAVTINVESPEKLKEKIAFFKKTASTQDVWEQESLYLRMKGIYPFTPSEIKPKVCFMFPGQGSQYVDMMKDLASKYKVVQDTFDEADRLLLKIIGQNLTDTLWSKPGETKEQIAVREAAIKKTEMTQPAVLTADIAMMRLLSSFGIKPDVVMGHSLGEYAAAVAAGIFDFENGLKAVCTRGKVMSEIKVEDNGKMASIAAPVDRVEPELARINGYVAVANKNCPTQTVIAGASKAVDDAIKMFTDMGIQAVQIPVSHAFHSAIVRPAMPQYRAFLDTLTFHAPKMPITTNVTAEFYPSDPEKIKDLMVTQISHSVEWIKQLQTTYDSGVRLFVECGPKRVLSALASNTLSDKKDIKVLASNHPKKGGIVEFNDLFANLISSGIHLDWKGTDMYGDNSTYNPAFVNWVTGNATPTEKAAGTVKENTVCACKVGANAAANGNGGKKSVVISGIAAGGPGSWDKIFREGVLDEILSGRNMIEPVSSEIQQKQIDKHVEFVIKSPDGNHRIERLSSPMQAIKLAAKGGAFDLEKEFGLPAKWVRSMDRSFQLAIAAGILALKDAGIPLVLYYKPTSTGGYLPDRWGLPADMIDETGVIFTSAFPVANSMMGDLSKRVAGLLNNKTAKEVRAFCDKFISQISDPALKAEIEAWYQANFKDKEIEPEAFTSEFILKTIIIAHSHFCQWIRARGPATALSAACASTAQAIAVAQDWITLGRCKRVIVISADDPTNDNVSEWILTAFLASGAATTEADVTKAALPFDRRRNGMIVGMGAVSLVVEEESEVAKRGMKPLAKLLATEIANSGFHVTRLDVAHVAQVMNRLVSHAEKEYGLNRSDIAKQLVFISHETYTPARGGSASAEAYALKSTFGKDVSSVIVSNTKGFTGHSMGAGLEDAIAVRCLNTGLVPPIANFKEADPELEGITLSKGGHYNFKYALRLAAGFGSQLGMTLLEKMWQEGEPRITDEARHQAWLKEISGQQAPVLEVVQNTLRIKDNYQHGVKPSLIMEGSQAFVDKVNAIHAHEAKAAAAPAAPAAVAQPAPVAPVAKAVALDEATVTKEVVKMVSEKTGYPDDMLDIDLDMEADLGIDTVKQAELFAALREHYGIAQQEGIQLKDYPTIRHCIKFVLANAGKPAAAAPVAQAAVAPAAPVAPAVTPAPAAVAQPAPAAKAVALDEASVTKEVVGMVAEKTGYPEDMLDIDLDMEADLGIDTVKQAELFAALREHYGIAQQEGIQLKDYPTIRHCIKFVLANAGKPAAAAPAAPVTPAAVPAPVSAPVTPASAAAPAAKAANLDEATVTKEVVSMVAEKTGYPEDMLDLDLDMEADLGIDTVKQAELFAAMREHYGIAQQEGIQLKDYPTIRHCIKFVLANAGKPAAAAPVAQAAVAPAVPVTPAVTPAVSAPVTPAPAAPVAQPAPAAKAVALDEATVTKEIVKMVAEKTGYPEDMLDLDLDMEADLGIDTVKQAELFAAMREHYGIAQQEGIQLKDYPTIRHCINFALSHAGKPAAAAPAAQAAVAPAAPVAPAAAPAPVSASVTPAPAAVSAPVTPAPAPQAAPAKLAKKPAHVVAEHIGVPQADALITNPTAPIEKHFSLAERPEREGYQGEHCHEKKLRYVTTVADAPLTERENRRLSKDRTILLFADNSQLIKAYQEEFKELGVKYHVFTTLKTRSKNTTIVNWESYEETEAALKDYAAEDPNIQGIVYLLGASVKKFDKKASPHADLTKYVMPLFIALRVFEKGLANRQDADTFFAVNTKIDGTFGYTTKDEFNPIVGALTGGTTCFRKDVYERTGAISKLMDFEPTATPDEMAQKTMDEVLHGDMRLMIGTRDNVRSTILSLPTRLDRSVKHFDLAGKSIIFTGSGRGIGAMLSQKIAAQYHSKIIVLDIIEIQDKTPLWASMNEAELAALKKQIWEDLKADKTQKATPVMLERAFGRVKDSITLYNNLQKLRDLGSEVEYYHCDVTNSSMVKEVCTKIKAKNGRVDGLIHFAGLERSKLIYDKDPAEYYRIFDVKATSFASFLANNIVRDDGFFAFASSIAGKYGNLGQSDYASANDYLAKSALSLSNQGYRAISIAMSAYKNVGMGVRAGVETFLRSNGVDFVDPEDGMQIFLDEIVYGQVPEIVLTGSLGRLDWDHQLKFEWEEIGADEAGSDDAPKGGTPAAAAPAASTPAAAVDASKATHFLGNITSLQKGAEIHLEKEFNLNSDPYLADHAIEGTPYVPGVMGIETFMETATALTGTVPQGLKDVHFYLPIKLLRNRPQAVRVIGKANGNEASMEIESDFINSKGVKMGNTRRHFTAKTLDGFTSTWNAVKAEAMTGLTAPMSVSKEEIYQKYFHGPSFQVLEGIVRVDKHASLAVYHTTPRPQWNDGPRTLLANPMLIEAAFQCCGFQDMSIEHKMTLPDGIAEVAVLKKELPPAQLYLYGVSRGNTADGKTLHDAYVFDAQGEVWVEIHGYQAIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC27</accession>
    <name>A0A1Y4DC27_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56606">
        <property type="protein sequence ID" value="OUO56606"/>
        <property type="gene ID" value="B5F75_05285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011988710" evidence="1">
        <location>
            <begin position="22"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="267" mass="30500" checksum="0517F0E9E6381A2B" modified="2017-08-30" version="1">MKKILVLLVVLLLESQSVVFGQSAYQLVRVAKRAKFKPVSTGKITGHVQAPLASASLAQYISSLRKPTSLRTYTQNRTFANKLGTVTVPEIHIELSFPAPILRSPSTLWGSYHYLRVLTSLSRERGAVHPKYIPLWKSIFYVGGYNGVHHIVNKSTLKEIYATMKREAMEKGQPWTIRLDELQRNAPGSLHPFHGRPEFSVLFHNIDRQLALYQQGGIRAIIIDYFDALDAFHKMYPNEAPFIPPHVRQNTLLEAKLWSETFHLKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC55</accession>
    <name>A0A1Y4DC55_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_05905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56152">
        <property type="protein sequence ID" value="OUO56152"/>
        <property type="gene ID" value="B5F75_05905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040423">
        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
        <property type="entry name" value="PTHR30443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="7">
        <location>
            <begin position="274"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO56152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="669" mass="77191" checksum="F801DA9519368E49" modified="2017-08-30" version="1">MKKNLLWAVSFVFLFAILQLVLQPVFQPWLMVSWCFSLCVYGTFSLFISSLFLCKYGRGWAVLCSLAAALPLLNFFYYQNYGAFIPSQLLTALMREPLFLLATLKMQLLPYAGWIILAGSGLAFFSCWCLHPLFKGEKQQPFALLKKWFIWLPALTIWLIQMKWCFKYDLHQVFPRSLYIVGLFGTVSFLAFIVKSKQRSLKILFISGFSLSAFFFALLGGPLKNQVPRLAFDAQFMVEIFDSLFSPERDKSLKQSETASDKYQAFQAPDIPFNVLVIVNDAQRARNMGIYGYDRYPDNPLKSFYQKSFVFQALSPANYTDTAIPALFTGQGPQRHPSAIKDALTLWDYFPQKFFTFYILTAGKKWARLDEFFNSFNMQYLWSAADDAGQKDALDYIQDEIALQQVGQVIKQHPHFVGVFHANSMHFPYFQQEGFTPFQPCETERTHWPQASVNCYDNAIYYLSHLEANLLNEIDLQRTIVVLTSDHGEGFYEHGAYFHNQDLHEESVRVPFIWYIPPALQQQIPATNWNHFVQNQKRYVSTSDLIPTILHLASLLTGQPPAFEREDFTGRSLFEDQTNRIVITSGCFVDYRCFSRDVAFADEHYFVLLRPNALDPVEIYPAFDFNQLHPLQVEEVDPEKLANIFSNAPHLHPLGGMLQSLLDVEKLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC76</accession>
    <name>A0A1Y4DC76_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CoA_binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56182">
        <property type="protein sequence ID" value="OUO56182"/>
        <property type="gene ID" value="B5F75_06080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="121" mass="12938" checksum="DAC56F9C89E892F7" modified="2017-08-30" version="1">MYENKTIAVFGVSADPSKYGYKIFKTLLDKGFRVFGINPKGGQVAGQTVFKELAFLPVKPDVAIMVIPPAALEGAVRQCAAAGVKEIWFQPGAQSAQAHEQAVNAGMEAVDSCFMADNGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DC98</accession>
    <name>A0A1Y4DC98_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_06230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56212">
        <property type="protein sequence ID" value="OUO56212"/>
        <property type="gene ID" value="B5F75_06230"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="77"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="413" mass="44912" checksum="69B208CAA8A0E85D" modified="2017-08-30" version="1">MKKILNLQCINCGKEHKTSEANFVCTACGGNLEVNYDYKLISKRFSIGKLKDNREFDMWRYMDLLPINDHDKVPHVHVGWTPLYPCKDLAKELHISNLFIKDEGRNPTGSIKDRGSAVAVARALELEQEVIADASTGNASDSLACLTASMPMKTVIFAPKSVPDPKLVQLLVYGAEVIGVDGSYDEAFELCKQSVQKYGWYSRAAGFNPFTREGKKTCAFEICEQLDWEAPDKVVVAAGDGTVLAGLWKGFTDFNKLGIIERMPQMIAVQAEGSAAIAEAFNTHSEVKSVSAHTVADSIVVNYPRDAALALQALQESNGMALTVTDEEILQAIPELARKANIFAEPAGAATYAALKKLVAQGKIERDETVVLVVGGNGLKDIDSAMQVLPKVCVIPPTMAAVEQELKAKGFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCG4</accession>
    <name>A0A1Y4DCG4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56282">
        <property type="protein sequence ID" value="OUO56282"/>
        <property type="gene ID" value="B5F75_06605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="101" mass="11313" checksum="BFD455923D38455E" modified="2017-08-30" version="1">MNTCPRCQNPTDETDNYCRHCGRSLKPGTGFLFSHTGIILLAFVLGPFALPFVWMSKTIGLGAKWIYTALLALISVYFVMVCYRSFLMLQEAAQTLMTVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCI4</accession>
    <name>A0A1Y4DCI4_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="6" type="ORF">B5F75_03185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56864">
        <property type="protein sequence ID" value="OUO56864"/>
        <property type="gene ID" value="B5F75_03185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="45" mass="5213" checksum="08707B90CD833946" modified="2017-08-30" version="1">MLPTYRPNKRRRAKHIGFRARMATAGGRKVLSARRAKGRHELIRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCK6</accession>
    <name>A0A1Y4DCK6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56843">
        <property type="protein sequence ID" value="OUO56843"/>
        <property type="gene ID" value="B5F75_03075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008523">
        <property type="entry name" value="DUF805"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05656">
        <property type="entry name" value="DUF805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="108" mass="12173" checksum="5916973C1AFF03D0" modified="2017-08-30" version="1">MIGRMGRLGYFIRLCILSVLYGLGVLFFTMGGKGQSLNPVALLFLFLGSGILLVSFLSWLSATVRRLHDMDFSGWWVLLVCLFPILVLVLCLWPGIQGYNRFGPPIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCM2</accession>
    <name>A0A1Y4DCM2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56904">
        <property type="protein sequence ID" value="OUO56904"/>
        <property type="gene ID" value="B5F75_03410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012644310" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="112"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="289" mass="31933" checksum="D43815A1E3D95B8F" modified="2017-08-30" version="1">MKKTFALAVCTLLGATAAFAQKGMNSAAYQQKAGAAATLKANEASLKQGVPQLKVNKTTTTTSVYDTSVRNKKGTTDSVIVEQSVTNAQGKTTTDGAVYESYTPSKAALTNDNRLEVSVAAGETYSYNKDNRSDRYATNGLAGNVNMLWHVSPHFAFGADYMMLHPRNKSHNHDGEARNYDDLYLHSIALAGKYTINAWDSWRLYVPMGWGMMNAKMKTHSDAARSSESKWGTGFYVGLGLQYDISARVFAGLEYRYTYAFISDKDLSAYGRDKDLQYHSAFLRLGMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN5</accession>
    <name>A0A1Y4DCN5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_06640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56362">
        <property type="protein sequence ID" value="OUO56362"/>
        <property type="gene ID" value="B5F75_06640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="46" mass="5020" checksum="D96ED30ECB2B0B50" modified="2017-08-30" version="1">MYEEKTFCLNCGGFTLIELLVVVLIIGILAAVAVPRYQTAVFTAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCN6</accession>
    <name>A0A1Y4DCN6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">B5F75_03515</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the gmhB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56924">
        <property type="protein sequence ID" value="OUO56924"/>
        <property type="gene ID" value="B5F75_03515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="19"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="55"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="8">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="188" mass="20835" checksum="6B323BD792618926" modified="2017-08-30" version="1">MKERIKAVFLDRDGTVIHEKPGTYLSDPAKVKLYQSAPAAFKLLKQCGFKFFIVSNQSGIGRGYFTEKEVNAVHARMLKLLRPAVIEEIAFCPHAPEQNCSCRKPKPALGLRLIKKYHIDPAQSYMIGDKKADVEFGHALGFKSVLVTTANGKNHLQKYPDLKPEKVASNLLNAARFIAKDSGAAHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCP5</accession>
    <name>A0A1Y4DCP5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_03355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56893">
        <property type="protein sequence ID" value="OUO56893"/>
        <property type="gene ID" value="B5F75_03355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="19"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="63"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="186"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="232" mass="26320" checksum="733CC9995119536E" modified="2017-08-30" version="1">MSQTPVNPVPQHVAIIMDGNGRWAQERRLPRLAGHNAGAKAVERTLKAAQKAGVKVLTLYAFSTENWTRPQEEIAGLFKLLAQTLSRYTQQADKYGVRLLVSGEREPLPPAILNQIDHAVSSTAHNTRFTLNLALNYGARQEIVHAVNALLREDKKEITVQDISQHLYQPDLPDPELIIRTSGEERLSNFLLWQAAYSEFYFSPVLWPDFDEAEFERALAAYRVRRRRFGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCT6</accession>
    <name>A0A1Y4DCT6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">kdsB</name>
        <name evidence="3" type="ORF">B5F75_03530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56927">
        <property type="protein sequence ID" value="OUO56927"/>
        <property type="gene ID" value="B5F75_03530"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="248" mass="27309" checksum="E668E7F8E5E6ECD6" modified="2017-08-30" version="1">MAVSDILIAIPARYGSSRLPGKILKDLNGKPVIQHVYEACKRTGLGDVVIATESPLVVEAVAKFGATAVLTSESCQSGTDRIFEAAQNRPEKFIINVQGDEPFISTETVSAVAELLRSDPSCDISTAVFATLDDAKIDNPNCVKAVIAKDGRALYFSRSRVPYKRELTEENKKAPYWQHCGIYGYRREALERFVQLPPSPLEQLERLEQLRALEDGMTIKCVETHPTGPAIDTAADLEAAEKYSKEHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCU2</accession>
    <name>A0A1Y4DCU2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_05645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56675">
        <property type="protein sequence ID" value="OUO56675"/>
        <property type="gene ID" value="B5F75_05645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013391279" evidence="1">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="117" mass="13073" checksum="5ABAD506D9DC11CC" modified="2017-08-30" version="1">MKKIFLLFPGLIVLSGCAAGINHNVAQINGQNYLIETKTNNFFGLSQWSSPSTLIPLEEEKEVVMPENYNPSTARAELAKIADECSIHSIKAQSRPNYKKMYKCIVDKLAELEQNAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DCW1</accession>
    <name>A0A1Y4DCW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57004">
        <property type="protein sequence ID" value="OUO57004"/>
        <property type="gene ID" value="B5F75_03925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012192775" evidence="1">
        <location>
            <begin position="25"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="611" mass="68298" checksum="06233C86629C251B" modified="2017-08-30" version="1">MKRTLLPALAGCLACLAFAVPAAAQPAFDFEDIDTLLEDNALNDAANRYASVLLSFFPERATRLGFSSANSKLTDRSASNNALALNALRSVKEMTDQITPSQLSKANQTDLLLLQNALAADIWQLEQNRPETDPLYYTEAFDAIYDLMLKKTTSSAQQRADLLARVNALPQVALQAQSNLIQPPAFLSQLAMERAYYAYLSFDEVTDFLLQGVEDEVSISQIKRDGQTAKRAIKQMFDWFKSLSQEQNTQDFRLGTEAYAQILKDRYQITEKPAKLEKKLQKEFLSAQKNLALALEPFTMETAEEEVTVVDDLNAKPTVQQTPAKTKKKGKFVPPSAQDFYKAAQRVAAAPAGGDLIRALSQDAASLAQFFEQDGTLPASAIRFSVKQMPAFYAYTQAYLFVPPFGNQLSPSSDLFLRLPSGNKLARQEQLKKDFNAPVRKLLLSGELVPGRYYQTVAGKNLSAIRRLYPSRSLANGWSAYAQRLARERGYLVTDEDLLFLAWNEYRRAAAALVDVRLQTKEYSYADALNFLVTENGFEQEEAETLLKDISAHPAESLSYIYGLQSLENARQKYAKKEGKEFNLSAFHSLVLQAGNVPPDQLEKEIKRLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD06</accession>
    <name>A0A1Y4DD06_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ligand-binding protein SH3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">B5F75_03420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56906">
        <property type="protein sequence ID" value="OUO56906"/>
        <property type="gene ID" value="B5F75_03420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO56906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="114" mass="12282" checksum="D8F003896ED0A01B" modified="2017-08-30" version="1">MKKLNPWIFVVLTCVFELLWVYGFNTASTGWHWGLVAGVIGLDFYFLTKACQSLPTGTVYAVFAAAGSAGTVVMDRFLFDETLSAGQLICIALLICGVVILKLSDGKEPSGGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD29</accession>
    <name>A0A1Y4DD29_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LPS export ABC transporter periplasmic protein LptC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_03830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56987">
        <property type="protein sequence ID" value="OUO56987"/>
        <property type="gene ID" value="B5F75_03830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012395835" evidence="6">
        <location>
            <begin position="25"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="179" mass="19885" checksum="9A447C910A7D01D5" modified="2017-08-30" version="1">MRKLFLLCLALTALAACDTSQEFAPDENAGMQVANKVSIFESQDNQKKWVLQAQSVDFSDMQTATLKNPELLLKENGKDSASVTGKTGSFDYLKKKVSIEGNAKIQSFAQQVVITADRFFYDVNKNRIWSDDKTVITRGGVKVTAREGVVTDSKLNNIEIKKQTTKLPTNTQELKNTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD65</accession>
    <name>A0A1Y4DD65_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56572">
        <property type="protein sequence ID" value="OUO56572"/>
        <property type="gene ID" value="B5F75_05100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="336" mass="36649" checksum="86EB4D6C4BCA230A" modified="2017-08-30" version="1">MNKFDAYLKERAKLVEKNLSKYISKIDNSPKILTDAMDYSLQAGGKRVRPILLMATAEAFGKKAADVMPAACAVEMLHTYSLIHDDLPSMDNDSLRRGKPTNHKVFGEDLALLAGDALLTYVFEVFAQNGKVKAIGAENTLNALLHFANCAGASGMVGGQVADVYAEGMGRSDAHSFRADKLRQNSKPLADKTLHYFMLPARIKETTPETILNYIHANKTGALIRGSVESGALLAGASGKDLTLIKKYANCIGLVFQIVDDILDVTASAKQLGKSNSDAENGKLTFVSLYGLEGSRKHAQLLIANAQKALDALKNVKKKNLWPLYEMAEFFKTRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD70</accession>
    <name>A0A1Y4DD70_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57027">
        <property type="protein sequence ID" value="OUO57027"/>
        <property type="gene ID" value="B5F75_04055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="325" mass="35896" checksum="7CF976CF8041FA4C" modified="2017-08-30" version="1">MAIIADKHYSLVDYAKQFDPSGQELAIAEVLSQSNDIIADALVTESSLDSGHEYAVRTGIPEGTWRRAYQGIEPAKATTKVVVESYGTLSAYSVVDKLVAEKGGHVEAVRTGQSRAIIAGMSNTMASNLIYGNAGQHPERFTGLAARYCELDGAESSRNVIDAGGETEGQNSSIYLVVWDTDKVFTFFPKGSKAGIQRVDYGLVNHVDADGNEYPAYKEYFEWKLGLAVQDWRYAGRICNIDVTNVPADLIDQMCELEERIQSLSMGKPVWYMNRTVKAALRKLTSNRTNVQYTPDQITSRPLMTFNEIPVHICDAITDTEDVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DD93</accession>
    <name>A0A1Y4DD93_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_04155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57047">
        <property type="protein sequence ID" value="OUO57047"/>
        <property type="gene ID" value="B5F75_04155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="205"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="535"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="580" mass="64334" checksum="83D01332CADAF3E0" modified="2017-08-30" version="1">MPCLPRPSVFIYHIHMNWKRTLALLVGMEMLFGAHPPGAGAFFPFSFRKQELKTDYSQTVWDRIMLEQSVTDMRRGMGEMAQARYKDASNSFAKAVIKNSKDPLPYLLLGASLYWMGQVDSAESEYQEALRLDPSNAMAYQLLGIASGWKGDVPQAQEYFLKANALDPNKADTHMNLGSTYAVQLNLDKALEHFRRAAELSPREPLYHYQLGTLYEALGRDEQAEKSFKKALKLFPYYEDAQLSLGALYEKLNRPQDALKYYKKAVRTKPGDYVARLRYASLLMRQGEADKAREVLEEAFSITRFKADGLALNAVYRASGRGAEAFREEIRQFQNSLEKVSPSKTVNIEVSLEYNPVSSPQNASDSRRGNTFEQAYQRLRADGNLAGASASRTFKRIFSLPAGSSQERAEQIEQFVAGLEQTLAQAGEGYNINLSLQGRTPDYASPSALTQDNTTAPKAVYDPRIVGNDMGLWVMGRTWLAFVDDAEEELADYAPQCPADGLCRLLQGVAALARGDAALAADAFEQAGKQAPQDALAWLGLGTAAVVAGDDAAAQNYYRQALKADPKNKIAKRNLKILAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDK6</accession>
    <name>A0A1Y4DDK6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57204">
        <property type="protein sequence ID" value="OUO57204"/>
        <property type="gene ID" value="B5F75_00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012147289" description="PDZ domain-containing protein" evidence="5">
        <location>
            <begin position="29"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="84"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="424"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="466" mass="51571" checksum="535284E6FDF3611E" modified="2017-08-30" version="1">MKSKKLNRYAVFAAVVFFVGTLFPYAYAAADNSLKQLRTLVDVVEFVKENYVETTDTDKLVAGAIKGVVNELDDFSQYLDPKDYKDLKNDTRGEFGGLGMRLQMVDDFVTVMSPMPGTPAFKAGVMPGDRILFVDDKDLADMKLEDAVELMRGPVGSKVKITISRKDEKGNYKTLPDFNFKREKIVPEVVYYRMLDGKVGYLYMVDFSGHSTEEVKKALADLQKQGMQSLVLDLRFNPGGLLTGAVDIAKLFLQPDEMIVYTQGRKPEYYQEFKTSAKPDYPDVPLAVLVNQGSASASEIVAGALQDNKRAFVVGQRTFGKASVQQVLPLSGGAGLRLTIARYYTPSGRLIQRDYRDKSKAEEGGIFPDVEVIVPAEEEVKVFMQYNNIVHTPGKKDPEVKFTEKDPVLDKAVEVLTGKLSLEDAKAQSQKAAEARKAEKEAKQNKTKDAAAETSDAPAKTQGAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDP9</accession>
    <name>A0A1Y4DDP9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56995">
        <property type="protein sequence ID" value="OUO56995"/>
        <property type="gene ID" value="B5F75_03870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="172" mass="18913" checksum="A5BFE8127639E87B" modified="2017-08-30" version="1">MNKKYINPLLHPAKAGFTLIELLVVVLIIGILSAVALPQYQLSVEKSRLAEVYTVVHKIEQNLTMIELSDAKFASNEEAAEAWLEDVGLPLEEGGVSGLKYAASKHFCYNPSMFGLIIMPKPCTDIDTAEYVMGFMPKSATSERAFMCQGKSDFGKKLCKSLCGAEECSLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDQ6</accession>
    <name>A0A1Y4DDQ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplS</name>
        <name evidence="6" type="ORF">B5F75_00290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57254">
        <property type="protein sequence ID" value="OUO57254"/>
        <property type="gene ID" value="B5F75_00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="133" mass="14589" checksum="17648FDF8A50EFB1" modified="2017-08-30" version="1">MNINEIKHNLKTNIPVFKAGDTVRVKVKVVEGDNERLQAFDGVVIARRGSGISETFTVRKISFGVGVERIFPIHSPRVDSIEVLKVGKVRRAKLNYLTKLSGKAARLQELKKVVPSTGEAEAPAAEPAKEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDR2</accession>
    <name>A0A1Y4DDR2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SWIB/MDM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57237">
        <property type="protein sequence ID" value="OUO57237"/>
        <property type="gene ID" value="B5F75_00195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SSF47592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIB/MDM2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="85" mass="9434" checksum="529EB44643060FCB" modified="2017-08-30" version="1">MAKANAKFMAPLTPSAELAAVVGSAALPRTEVVKKMWDYIKKNGLQDSTNKRMINADEKLAAIFEGKKQISMFDMSKYLSKHLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDR8</accession>
    <name>A0A1Y4DDR8_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rsfS</name>
        <name evidence="6" type="ORF">B5F75_00340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Might have a role in establishing the nucleoid structure of elementary bodies.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H1/H5 family. HCT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57263">
        <property type="protein sequence ID" value="OUO57263"/>
        <property type="gene ID" value="B5F75_00340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009970">
        <property type="entry name" value="HC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07382">
        <property type="entry name" value="HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="123"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="161"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OUO57263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="190" mass="20525" checksum="3DD7FCE4A85853CC" modified="2017-08-30" version="1">MNTKELVCLAARLADGKKAENIKVIDLGGLSSLCDYILIATATSKPHLDAVEEEISKKLKELGYYKLNRDGGDSNLWRVSDYGGFLAHVMTQEARDFYALDKIFSFGKEINFNEPVKKAAKKKPAAKKAAAKKTTVKKTTAKKTTAAKKTAASKPAVKKTAAKKTTAKKAVSKKTAAKKTTAAKKTASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDU9</accession>
    <name>A0A1Y4DDU9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="9">5.3.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmhA</name>
        <name evidence="11" type="ORF">B5F75_00500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the SIS family. GmhA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="9"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57293">
        <property type="protein sequence ID" value="OUO57293"/>
        <property type="gene ID" value="B5F75_00500"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00041">
        <property type="reaction ID" value="UER00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008968">
        <property type="term" value="F:D-sedoheptulose 7-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001061">
        <property type="term" value="P:D-glycero-D-manno-heptose 7-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00067">
        <property type="entry name" value="GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004515">
        <property type="entry name" value="Phosphoheptose_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="32"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="115"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="185" mass="19964" checksum="432F7FFB305B70AD" modified="2017-08-30" version="1">MFVKQQADELIQAVTYVKENLADKVEELAAKVVEAFKRGNKVILMGNGGSAADAQHIAAEFVGRFKKERPSLPALALNTNSSTLTAIGNDYSYDVVFSRQIDGFAKEGDVVIGISTSGNSKNVYLALGMAKRKGCFTAAFLGKDGGTIKDICDLPLIVNVKDTPHIQACHIFMAHCMCDLVDQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DDW1</accession>
    <name>A0A1Y4DDW1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57287">
        <property type="protein sequence ID" value="OUO57287"/>
        <property type="gene ID" value="B5F75_00470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012486418" evidence="2">
        <location>
            <begin position="20"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="302" mass="34409" checksum="27359BC1B6A2A6C9" modified="2017-08-30" version="1">MKKFLLLLCILFAAPLARAQEISVVETRAAESVPFAQPFALQFVLSHTPGYQVTVQEESLSPQFEITQVSSADNSPGTVTYDFTALPFALGKTTFTVTFELSQDGKPLAQTKQEVFINVPRAQTFDDPNLREIRPPHIPSGWLAWLVALLLLGALVYVWRYWYKRLHERARTIRLEQDTRPGNVIALSKIDALLDSGLWENQQYKLFYIALSDILREYLWRQFHIDASADTTAELLRRVKNMPQMAQLMYQLRDFLSSGDLVKFAKAVPSQQIRDKDVQLLREIIIETSPKELAPEAPKEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE53</accession>
    <name>A0A1Y4DE53_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_03555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56932">
        <property type="protein sequence ID" value="OUO56932"/>
        <property type="gene ID" value="B5F75_03555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="40"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="234"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="530" mass="58939" checksum="01DADB74DE7A754E" modified="2017-08-30" version="1">MNKPAPNEQMPDFSCLPAYLQQALARLDITVPTPVQAGAVPPALQGRDVLATAQTGTGKTFAFLLPLAVKLAENPQENALILSPTRELAQQTQEELKKLFSEAFSLPTALIIGGDNIHKQYADLRAHPRVIIATPGRLMDHMGRKSVDLTKTHLLVLDETDRMLDMGFIDDMRRIVAALPAPRQTLLFSATLPEQIQTLAREFLTRPVRVQIGSVVSPADLVVQEIVRVDVREKLPQLLHELNTRKGSVLIFTRTKHGAERLAKQLKLYGQKANALHGDLRQNRRRQVLEFFRNGTVRILVATDVAARGIDVPHIAHVINYDLPQCPEDYIHRIGRTGRAGTVGAALSLISDDGEKWKEICKVTRFSIPVKTIQKTIEPLPAPKFVAQEEGAAHGKSRRARVHQTSRPSKATALAKQLLQEGEVDLPQRSAALADSKAPFRQVPNTLPAKREETKAFPLRPQKPKTFRKALAGASVLAEETTQNPFRTVKVGASKKTLRQTARRKTENPAWEKSKTGHKNVKKFSKRKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE64</accession>
    <name>A0A1Y4DE64_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_01030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57387">
        <property type="protein sequence ID" value="OUO57387"/>
        <property type="gene ID" value="B5F75_01030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="142"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="359" mass="40011" checksum="815478CCB93BEFE4" modified="2017-08-30" version="1">MSAFFVVASIVLWLMQVTVGAWLYFAFPQIGWKVPVAAVPLLMTVLFQVFMSYTRTHWGVWESWAYYFAYAWAGLAFLAFCICAVCAFVQWGLFFFHVQARAWLGPLSVGLMAVTAALAVYGGVASPRVKHISVTLPGAPKMKLALLSDAHLGMGVSLNRLDKALKRVEEQKPDALLVLGDIFEYGPNRLAYAKRLAQVQTPLGAYGVFGNHEYYVGYDASKEFYKEAGIKLLENELAQLPNGVQVAGVKDVRTAHVRARDVEQLLRQADPARTLLYLSHTPLYAEEAARQGADLMVSGHTHNGQIFPFNFLVRLQFPRVYGLFAVGQMKFYITSGLFYWGIPLRFLAPAEIPIIEVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DE81</accession>
    <name>A0A1Y4DE81_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57407">
        <property type="protein sequence ID" value="OUO57407"/>
        <property type="gene ID" value="B5F75_01135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013096542" evidence="1">
        <location>
            <begin position="20"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="390" mass="42401" checksum="0C3BF2631ACAF137" modified="2017-08-30" version="1">MRAFLFVLSCLLTVPFAAAQKLPAKNFLRGGLAPAKIEKNILLNLRYIPPASLAAQSAFQTAKTAVVKPPVRNEQEVADFSPLQRTIARQTLGGLQAPAETTSLAQTEKHIRASLVEVVGRASGDLMGSGFVVQSRSGRLYAVVSYHVVGRKGNTVAVRTYPEKGAPVVYNGLIVNAAGSFGINAPDAAIIALPQEAQAYVRPLTIAPSLPEKGSELVVWGSPYACEGFARIDELKVTLAQGIKMVMDSPDVSEEFNGLCGSPVLNAQGQVAGIYSGHDPEQGQVFAVNARQALEWLLESYEQGKLPAPLTYKVYGRDVLQIQAEETIGWVYHFDQGGTLLHKVYLPKYNGRFDPEHAEWLFPDVQHGDFLEFEIVKHRFVDRTVSVGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEA0</accession>
    <name>A0A1Y4DEA0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="13">NADH-quinone oxidoreductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">B5F75_01435</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57463">
        <property type="protein sequence ID" value="OUO57463"/>
        <property type="gene ID" value="B5F75_01435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="569"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="599"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="627" mass="67436" checksum="263FA795D3F43F20" modified="2017-08-30" version="1">MPTKNIEKIAKDYKDAYKKITGRVVICGGTGCIAGGSLKVYEAFQKEMEKRKIGFCLQITKDCHENYLSLSGCRGFCAMGPLVSVGDIFYTKVKPEDVAEIVEKTLIKGEVIDRLLYHNPANNQKAKTVDEIPFYAKQERILLHDCGRINPEDINEYIAHGGYAQAKRAYTEMTDEEVCKEIITSGLRGRGGGGFPTGKKWDLTRVEPGPKKYVICNADEGDPGAFMDRSVMEGNPNAVLEGMMIAARGIGADEGYIYVRMEYPLAIQRVRTAIKQAEELGILGENIFGSGKNFKINVMEGAGAFVCGEETALIASVEGKRGMPKIKPPYPSQSGLFGKPTVINNVETLATVPKIMEMGAEEFRKIGTLGSPGTKTFAVTGHIANTGLVEVPMGTTLRQVIDDVAGGTTNDDGTVNKAAFKAAQIGGPSGGCLTREHLDLPLDFDSLKSAGAMVGSGGLVVMNNKTCMVNVARFFLEFTQRESCGKCVPCREGTEQMLTMLNDIVEGRATLKTLENLEDLAKAVQKASLCALGKTAPNPVLSTLKHFREEYLAHVVDKCCPAGVCKALARFEIVASKCKGCGMCKRACPVSAISGEVGKPHHIDPKKCIKCGGCKSTCKFGAVVTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEB0</accession>
    <name>A0A1Y4DEB0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_07180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56049">
        <property type="protein sequence ID" value="OUO56049"/>
        <property type="gene ID" value="B5F75_07180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="205" mass="23113" checksum="ED58E3E80919D594" modified="2017-08-30" version="1">MRRIQLIGILVAFMVGMTGVSFAKDKADTIRFAGTQYTLQYSVGNAQERLNEYLPAGEDFSSYSTMFTVRSYDALQNTPQEVASSVIYNLQQHYPGTEYSFFPGKGSDAGLSFIATKPGIFEFNFFRFTTHQGHPVALQFVYREYPNAKNEDQVRQKMVQTIQKNATAWENEMLSMPVPAIQPSAQKPAKAPAKTKNKKKNLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEC8</accession>
    <name>A0A1Y4DEC8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Solute:sodium symporter family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">B5F75_01190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57416">
        <property type="protein sequence ID" value="OUO57416"/>
        <property type="gene ID" value="B5F75_01190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OUO57416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="532" mass="57789" checksum="5D90D6A32D4B33A8" modified="2017-08-30" version="1">MLLTISSFVGFTALVLGLSYYLTRKKDASSSEGYFLAGRGLTGWVIAASLLLTNLSTEQMVGLNGQGYMFNMSGIGYEIGASLALIIVAFFFLPRYLKKGYATIPDFVGDRYDSATKQFVNFLFLAGYVLILLPTVLYSGAIGMGGIFNIMDTFGMSEMMAIIVVVVAIGVLGCLYTIFGGLRIMAIADTLNGIGLIFGGLMVPLFALAYVGGGDILGGLTEVVKAHPEKFNAIGGPNDPVPFATMFTGMFLVNLFYWGCNQTIIQRALAAKNLKEGQKGLFLAAIFKLIGPIYLIIPGIVAFHIFQDNPLKVGDMAYPMLVNKVLPFYLIGFFAAVLFGAIVSSFNAALNSSSTLFMLNVYKPLIKPTATDEDLVTKGKYVGIILAIFSMCVAPLIAMAPSGLFNYLQMVNGFYNVPIFTLIIFGMLNKTAPAWAAKVTLIFFMIGYGLTQLGIVKTDLHFLHVLAILFVISIVFMYITGKFWPAKNKYDDGKDLHIVDTTPWNMRVVVSIAIVLCVFGVYVLFSRMGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEF3</accession>
    <name>A0A1Y4DEF3_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57457">
        <property type="protein sequence ID" value="OUO57457"/>
        <property type="gene ID" value="B5F75_01405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012508810" evidence="1">
        <location>
            <begin position="18"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="311" mass="33757" checksum="BB0694FB4052262B" modified="2017-08-30" version="1">MKKIVLCAMALLLAACAGMNKNTVNYQMGGYDSVKYYVVAGEGMSKEEAAQNALENMRREMVQNAPAAANQGVVTDLMANAEVEKVWRDKDFDGKHFYALAVLSRSNAHKVLAPLLDQEDAKLEGLAKQFAAPASALADLKIAFKMQPVVARRAALDEMYQFLNASRESYQPEVFAPYKAALQEKMAAVLVGVDVTGVQSEVLVTYVVDALNRMGLGVVDASDPDKVLLVQIATDVDAYDSQKVEGLVWCSSGASVSLVDVERGVTFSRFNVHERAGTSRAEDSLRKSMQSVGEQASAQISSRLKAYLNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEK5</accession>
    <name>A0A1Y4DEK5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57072">
        <property type="protein sequence ID" value="OUO57072"/>
        <property type="gene ID" value="B5F75_03095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="127" mass="14780" checksum="1915082A1F616B80" modified="2017-08-30" version="1">MNICSYVIIKRIFAMNKKTKLSTAHVCKPSLELPEETLYDLADLFKVFGDSTRLRILCALFDCEQCVQHIADELGMTHSAISHQLRFLKQNKLVKNRRQGKTIFYSLADEHVKRIFNQGLEHVREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEL6</accession>
    <name>A0A1Y4DEL6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_02230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57613">
        <property type="protein sequence ID" value="OUO57613"/>
        <property type="gene ID" value="B5F75_02230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="231" mass="25962" checksum="12EDF53A2C35609E" modified="2017-08-30" version="1">MPQYFADIKETEFFLMDAEAHHACAVARHQEGDEIRVFDGTGRQYMGRIDRIQKKFVRGTLLRPCPVRRPALELELCFAPNSRTGLEDVLDKCTQLGVAAFRPVVTERSEYDVLKKWDGKNDRWRQIMIAACKQCDTPFVPAILPPLKFSQAIGQEIPSLIAYEAEETHTLAWGLEKLAHPKRLRVYVGPAGGWTDEEIVIAAQYNVLPVTLGVNILRAETACIAVAAKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEP9</accession>
    <name>A0A1Y4DEP9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DAGKc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57546">
        <property type="protein sequence ID" value="OUO57546"/>
        <property type="gene ID" value="B5F75_01875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="295" mass="31724" checksum="583862A0D637EBCD" modified="2017-08-30" version="1">MKLLFILNPHSGKLKGDADKIEAIGKAIQLNFPGADMRLTQAPGHATQLARAAVLAGYQAAIAIGGDGTINETARGLVGSQTALGVIPNGSGNGFARELGMPLLPQEALARLQKPRPFPCDVGYANGELFLNLAGVGIEADIAWQFMEQGKTGARGMWPYFKIGARTAFTYKPKTIALEVDGQTRTLAPLTLVFANGRQYGSNFKIAPEASLTDGQLDMVTVSDAPKWKLALAAPSFFTDKWRPFGITKTEHVKKALITRPGEIIYHIDGEPRKTADKLEISVAPAALTVWRPCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ1</accession>
    <name>A0A1Y4DEQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_06165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56199">
        <property type="protein sequence ID" value="OUO56199"/>
        <property type="gene ID" value="B5F75_06165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="310" mass="33276" checksum="2BE312FF17C44EFB" modified="2017-08-30" version="1">MKPVVFITAGDPLGIGPEVTVKALKSPLVQHACSPIVIGEPCSLFRAGFSDRLARLISMDTCECLQDAPHGPTEAGGLSSFKSVELACKLALRTHCPLVTAPISKQSWSLAHIPYVGHTELLRERAGKEGLMMFVSGPIRCALVSEHFAISDLPHILTRSRVSQAARHFAQALQRLGVKHPHIAFCALNPHAGDNGKFGTEEHSVIEPVIRAMRRKGICAEGPFPADSIWAAHAHGKYDGLLCMYHDQALLGLKLAAREPIVHVTAGLKFLRTSPTHGTAFDIAGKNKANAQSMTAAILFAAARAKCPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEQ5</accession>
    <name>A0A1Y4DEQ5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gyrA</name>
        <name evidence="10" type="ORF">B5F75_02445</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57653">
        <property type="protein sequence ID" value="OUO57653"/>
        <property type="gene ID" value="B5F75_02445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="9">
        <location>
            <begin position="25"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="539"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO57653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="839" mass="93193" checksum="909AC233F6C0391A" modified="2017-08-30" version="1">MSEETNNQPQAQNANVDLFGNIQQRDIAGEMRSYYIDYAMSVIVGRALPDVRDGLKPVHRRVLYSMNEMGLKYNKPYKKSARVVGDVLGKYHPHGDTAVYDTLVRMVQDFSLRKPLIDGQGNFGSIDGDSAAAMRYTECRLQRISEEMLGDLDKDTVKMIPNYDGSLMEPSVLPAKLPALLVNGSSGIAVGMATNIPTHNLGEVCDGIIAYIKNPDISTKEMMKIIKGPDFPTGAIIRGTKGIYEYFETGHGSVKVQASTEIEQRKNGREAIIVTAIPYQVNKTALIESIVGLVRDKKVTDISDIRDESDRRGMRLVIEVKRDGNAQVVLNHLFKHTQLQTSFPVNMLAIVDGRPRVLSLKEVMKAYVKHRQEIVTNRTKFDLNKAQKREHVLNGLLVAIANMDEVVAIIRKAKDPTEAKFTLMSRFTLSEVQAQAILDMRLHQLTQLSALAIENERKDLLKLIADLQDILGNPQKVLDIIVEELQELKKDYGDPRRTEIGSDVTDFSMEDLIEKEDVVITISNDGYAKRIPLSTYKSQNRGGKGIIGSRTKEEDFIEHLFITSSHATILMFTNRGRVFALRAFEIPEGNRLSKGKAIVNLLQLTGEEKVTSAVAIEEFNPKHCDNTYLTMCTRFGSIKRVELSEFANIRRTGIIAIGLEEGDVLVGVQTTHGKSDIIVATKNGKSIRFDENQVRSMGRPAKGVRAINLAQGDVVVGMEQAPADEPQPDVLSVCENGFGKRTEFSEYKRQNRGGMGVITIKTSARNGSVVGIKLVDESKDLMIVTEKGMTIRVRCADIRSVSRNAQGVTLAKLEPGDKIARIAPVVKDDEEHEPEEASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DES2</accession>
    <name>A0A1Y4DES2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">B5F75_01125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57405">
        <property type="protein sequence ID" value="OUO57405"/>
        <property type="gene ID" value="B5F75_01125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044005">
        <property type="entry name" value="DZR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18912">
        <property type="entry name" value="DZR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012011566" evidence="1">
        <location>
            <begin position="24"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DZR_2" evidence="3">
        <location>
            <begin position="12"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="2">
        <location>
            <begin position="152"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OUO57405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="243" mass="26906" checksum="3E27FF3CECA98747" modified="2017-08-30" version="1">MKKTLKTLWRLLLHFFFPRTCFACGCDLPWRREEPLCAACAQGLKTPGPHICRRCGAVLTEGGAHCYACRGSKERAYKCRVIRSAFVFNTSSRALVHALKYAGADYLARYMGGLMAKRFARYPELAAAEVVMPVPLFPRRGRKRGYNQSELLARFFAPQVGLPVQTKALVRVRNTVSQTKLGRAGRLQNMAGAFACRRPEWVKGKTVLLIDDVATTGATLEGCAAALKAAGARRVLAYTFARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DET2</accession>
    <name>A0A1Y4DET2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RDD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_01185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57415">
        <property type="protein sequence ID" value="OUO57415"/>
        <property type="gene ID" value="B5F75_01185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="32"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="288" mass="32469" checksum="508DC570E273B3BE" modified="2017-08-30" version="1">MIEKRINIMEPEIPTLQQPPAEEPAEKKQVEYASVTERFVALLIDYGVVFIPAQLIARVILNIMGPITELWQIASIFIGINLLFILYETILSSGDRVTLGKALVGIAVVKKDLSGPISLPRAFLRAIGYYFSAALLMCGFLLAFFDDKHRALQDFLGGSVVVQIREKTWMERTMVRLLGGVLLVAFAATSYTQFFGRGGTLQQFYIRRAQEHLGKIALLEEAHYNRYGSYTNDLLRLSLLSGDPVQFQRDTQKVLYPKGFKIGVQGNYYKISARARDARNTPVYFTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEU5</accession>
    <name>A0A1Y4DEU5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Semialdhyde_dh domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57693">
        <property type="protein sequence ID" value="OUO57693"/>
        <property type="gene ID" value="B5F75_02655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="1">
        <location>
            <begin position="3"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="292" mass="32522" checksum="DFB3E2B6B5803893" modified="2017-08-30" version="1">MKTVGIIGINGMVGQNMLAELKKINTPFEIKTFGRNDEITPLDIAVLCTDNPVSAQIAPQIKDRVKFTVDMSSEFRMTPGVPLVIPEINAHAITPNTPLIASPNCTTTGLVMSLAPLAPHYHFTEVFFCSYQAISGGGKKLLDDFHTPGSYYENNCVPLIGSVQPNGHTSEELKGLYETRKIMEMPHLKVYCHTVRVAVENSHSLGVTLKAKENFDLEQVKKLWNAFPNLVYSEKVITPKEASGLETTFICRLRRDVEEPNIIHYFVTFDNLLKGAAMNGRQIVELLLEKFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DEZ1</accession>
    <name>A0A1Y4DEZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin_Reduct domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57646">
        <property type="protein sequence ID" value="OUO57646"/>
        <property type="gene ID" value="B5F75_02405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="170" mass="18571" checksum="A200CB30A81B4F60" modified="2017-08-30" version="1">MSAQDINEGLHYVTYGLYIVTTADEGKQNGLIVNTVFQVTAEPARVAISVNKKSLTHEMITKSRVFAAMPLEQQTPLPFIGIFGFRTGRTFDKLAKVPHKTGFLGCPIVTEHTLSYMEIEVCQTLDVGSHTLFVGEVKDAGVIKPQGTALTYAYYHDVIKGKTPAGATHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF03</accession>
    <name>A0A1Y4DF03_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="9" type="ORF">B5F75_00575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57704">
        <property type="protein sequence ID" value="OUO57704"/>
        <property type="gene ID" value="B5F75_00575"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="147" mass="16699" checksum="9486F6311C7B8C85" modified="2017-08-30" version="1">MLLSVVAGIFLLDHITKVAAFFYLPDQPVELLPFFHLTYVENTGAAFGMMQNGNFLLIFVMLAIIAYIIISWRELCSCGSLVKWGAVFILAGALGNLYDRILLGFVIDFLDFRVWPVFNVADSFITVGGCMFVISLFMQRRKKREER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF07</accession>
    <name>A0A1Y4DF07_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57222">
        <property type="protein sequence ID" value="OUO57222"/>
        <property type="gene ID" value="B5F75_00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="429" mass="48963" checksum="8A67AB1730E7D49C" modified="2017-08-30" version="1">MKETVILGGGIAGLAAAYRLRQAGRSARIFEKDAEWGGLCGNFTIDGFRFDRFVHFTFAPDPNVQKLFSAAGPLLNHPPVSSNYYHGYWLYHPAQNNLYPLPTDEKVKIIKGFVHRRQIPVEQISDYDTWLRVQYGDYFAEHFPFAYTRKYWGAQPKELETKWVGNRMHSPTLEEVLKGAFEKPTENFYYTSVMRYPQKGGFKSILHALAQGADIALNKKAVFIDPRVKRVKFADGTATAYGELLSSLPLPEIIRLLPDVPEPVQQAAKRLRHTCGYQISLGFNKPDIAKYLWFYIYDEDIPPARVYSPNLKSPDNVPGGCSSLQAEVFYGNTAPVPPAEQVLDTTLEKLRQMGLFNSADIAVKDIRFEPYANIMFDHAIYQNRQTVLDYLTSLGIYSMGRFGKWAYFWTHQAFEDGKNTAEQVMHEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF69</accession>
    <name>A0A1Y4DF69_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57575">
        <property type="protein sequence ID" value="OUO57575"/>
        <property type="gene ID" value="B5F75_02030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="161" mass="17611" checksum="E4B3F8E3DEA7AE7C" modified="2017-08-30" version="1">MQTKQGFTLIELLVVVLIIGILAAVAMPQYEKAVLKSRMSSMWPILKSLKTAQESFFLANGTYTDDLNVLDITVPKGDLRSNSAVGQEDYNNGTCLDNLYGTTQDKWVVAGGIGKDCDSGATNGCLIKLWLDHSTRPGEIECEGTHPKCAELCRTFDFVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DF97</accession>
    <name>A0A1Y4DF97_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57322">
        <property type="protein sequence ID" value="OUO57322"/>
        <property type="gene ID" value="B5F75_00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="158" mass="17015" checksum="A2D69BF7515226CA" modified="2017-08-30" version="1">MKKGFTLIELLVVVLIIGILSAVALPQYTKAVEKARMSNAISVLSSIYKAQQVYYLANNQYAQKLDDLDVGVTGEDVDAVGDGVVAFGPLKKTQDFIFGAWTMTTNVPGMASASRIDANGHVAYVMMMTMGGTRFCNASAYATDAQSKLCADWRDGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFG5</accession>
    <name>A0A1Y4DFG5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">B5F75_02555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57675">
        <property type="protein sequence ID" value="OUO57675"/>
        <property type="gene ID" value="B5F75_02555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="77"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="197" mass="21924" checksum="31310382632CAE34" modified="2017-08-30" version="1">MKSLDRFIRALRRLPGVGPRQAERFAAYFLRASQGETEEFIHALAAIKQDVKLCPQCFSYSEDGLCEICRDPDRDRGLICVVEDPQDIESLEKTGAYKGLYHVLHGAISPMDGRGAEQVKVRELLERVQHAQPPVREVIIATDPDSEGETTALYLADLLRGLVGQVTRIGYGVPLGGDIDYMDEMTLGYSLKGRTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFP2</accession>
    <name>A0A1Y4DFP2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_01430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57462">
        <property type="protein sequence ID" value="OUO57462"/>
        <property type="gene ID" value="B5F75_01430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.260.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003149">
        <property type="entry name" value="Fe_hydrogenase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036991">
        <property type="entry name" value="Fe_hydrogenase_ssu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013352">
        <property type="entry name" value="Fe_hydrogenase_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019574">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02256">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00902">
        <property type="entry name" value="Fe_hyd_SSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="SSF53920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02512">
        <property type="entry name" value="FeFe_hydrog_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="8">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="182"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO57462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="579" mass="64054" checksum="377D8FEA7FAB5A6C" modified="2017-08-30" version="1">MEKEQFVTIEGKRVPIEGEKNLLELIRKAHFNIMTFCYHPELAAYGACRLCLVEVEGMGIVASCTVKPRDGMKVRVNSDEIRHLRRINLELLLSSGNHDCTLCSKSNNCKLQKLAKDMDVTEIRFKSKKLDSHKDATSPALVRDHSKCILCGNCVRICNEVQGIGAIDFAFRGFRSKIATAFNKELGQSHECVSCGQCARVCPTGALMPNSSEIEHVFEAINNPKKKVAVHIAPAVRVGLGEMFGLPQGQNVDGKIAAALRMLGFDYVYDTAFAADLTIVEEATEFLERFKKGTNLPQFTSCCPAWINYVEKFAPEFIPNLSTARSPMQMMGPILKADYEDKGGKREDLVVVAVMPCSAKKTEAKRDEFYVNDNPDTDYVVTTVGLARMIKEAGIDFVNLENEWFDMPFGTKTGAGVIFGASGGVMEAALRYALAELDPANARSVKFSSLREGKVFKEKTVEVGDIKIRTAVVSGLKNARKLLDDIKAGKDHYDFIEVMSCQGGCVAGAGQPQFDGWAPRQKRAEGLYQEDTELAYKSQDNSGVQALYGRILDKVGGPLAHKLLHTHYFDRKDRTGQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DFZ9</accession>
    <name>A0A1Y4DFZ9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">B5F75_02015</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57572">
        <property type="protein sequence ID" value="OUO57572"/>
        <property type="gene ID" value="B5F75_02015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="20" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="164"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="264"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="469"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="517"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OUO57572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="589" mass="65413" checksum="67B50C2C2CFB6921" modified="2017-08-30" version="1">MKNSNQEHSMLVLKGVAASPGVAIGPAVLLPGESFAVTRQYIEAGEVKAELQKISTAMQKTLAELDACEQKVLSTLGTEYANLMSTHKLILQDPSLKESVAKKIRTEHLSAQAAIFLTLQELAASFDKIEDPFFKERRNDIFDVGKRLVNNLEGDKREFLASITKPSLLVAHNLYPSDTINLQENQVIGFCTDVGGKTSHTALLAQSLNIPAVVGLSTASKDVKSGDTLIIDGENGLLVINPDKYTLANYRKIQKEIKKTEALLKTINHLPVITEDGHAVKLFVNYDPRTDNKENKRLITDGLGLLRTEFLYMNTPHPPTEEEQYQVYLSVAKRFDMRPVTIRLADLGADKLPDFPLDEFDQDANPFMGCRGIRLFLKNPDLMFTQLRAIIRMSCEVPAQVKIMVPMISSVEEVRHVRNAFEQVLKEFEAKGKKPVNRVGLGAMIEVPAAAIALDGMIQLLDFISIGTNDLIQYLVAVDRVNQEVAHMYDPCHPAVGRTINQIIQTAHKRGRKVSICGEIASDSKMLPLLLGLNVDALSVTPRMYLRVKNNIRNLNFENCSDLAQAALLMGSSEEIRNLIEQNDKNEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGS4</accession>
    <name>A0A1Y4DGS4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_05770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56128">
        <property type="protein sequence ID" value="OUO56128"/>
        <property type="gene ID" value="B5F75_05770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="6">
        <location>
            <begin position="6"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="7">
        <location>
            <begin position="185"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="8">
        <location>
            <begin position="290"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="5">
        <location>
            <begin position="434"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="495" mass="54878" checksum="9881C87ECFE61A98" modified="2017-08-30" version="1">MSEDIKFSTAGFRAVTADGLTAQSVQRLAYGISEHILEHPFYGFEGEGYRKHCAAQGKKPKKPLVLVGYDTRFFSKQFAYIAANALVQSGITVKVAELPLPTPVAEWAVLNECAVGAIVVTGSEAEYYVNGVKWISYYGGIANNEIVQDIEKRIPSPSAQILKASSTEFGYLNAAAIVTKDLRKSYLARLEKMIDVKALKKSKLKIAVDPLFGTAKHYFRDFLEKYGVTVEGIHEGDDVLFGGHTPNAGPVSLTDLKKLVTSKKMHLGIACNPDCDKFGIIDADGNWVSPNEIAPMILEHMVRNKKLKGRVCRSVITSNLIDQVAKMHGLMLRETPVGFKYITELMTTGQYIMGMEESGGIAVASHIPDKDGLLACLLVVDMLAVEGKSFKQLKKDFYKKYKQLFDQKVSIPKTETEINRIMERLDIRPPLSINKTSVWRIDSTDGFKFILKGGSWLAIRPSSTERLIRMYAEAQDEKLPAALIKEGKKIIDSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGU5</accession>
    <name>A0A1Y4DGU5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MerR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_05880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56148">
        <property type="protein sequence ID" value="OUO56148"/>
        <property type="gene ID" value="B5F75_05880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="125" mass="14749" checksum="02B089E66B551235" modified="2017-08-30" version="1">MTISEVSKKYGLSVDTLRYYEKAGLIPPVNRKENGIRDYTETDCGWVEFVKCMREAGLPIEVLTQYIALYAKGNRTLQQRKNLLVTERDRLKERIEQMQQTLKRLNYKISVYEQRIVACEKKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DGW2</accession>
    <name>A0A1Y4DGW2_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_06000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56168">
        <property type="protein sequence ID" value="OUO56168"/>
        <property type="gene ID" value="B5F75_06000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013186884" evidence="6">
        <location>
            <begin position="23"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="440" mass="48771" checksum="2A4600C07F9593CE" modified="2017-08-30" version="1">MKKLLAWPLVAALFLSGATAFAQGMIADKYRAEMLPRFVSYVQIDSMSDNRAEWMTPGQEKMAQFLYDEIKAFGFPTYFSKDKYIYVNIPSNLKTRKAPKLGLSAHYDTTPDIIGNGVKPQVIKNYDGNPIVLKNNHVINFKSDPYLKNMIGKTIVTSDGTTNLGADDKAGLTIIVTLLQTLAENPKMPHGPIDIVLTPNEDVGRSAERLELEYYHPDYAYDFDGGVNGEVVIANFSADRVVVTAQGVNGHQSYAADNGYLNSVKPIADLIAVAVPTKFLPNHSRGDQGYLEPHHIEYDPVKNTHMVDCRLRYFDPEEGKRYLQGIQHTADSLQQVLGTKITVEITKQYENVAYGVKPEALGLLTAAMKEAGVTPKTQKERAGTTSAMIMAKHGFGGYTVFTGQNNPHAFTEWLSEEDMFKAYKVALNLVKQVAQMNATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHZ1</accession>
    <name>A0A1Y4DHZ1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">B5F75_05025</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56558">
        <property type="protein sequence ID" value="OUO56558"/>
        <property type="gene ID" value="B5F75_05025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="8"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OUO56558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="226" mass="25078" checksum="B5DEF05EA4329567" modified="2017-08-30" version="1">MRTNGMLIAIDGTAGTGKSTVGKAIAAKLGYGFLSTGEMYRALAYKVFEKHIVPEDHDAVLEAARQLHFTFVRQPDAALKMYVDGEYLGAKLHLEEVGNVASRVSTNGEARRVLTEKMRDVGDDGGVVMEGRDVGTVVFPDAEMKFYLDASAQERAKRRVKQLQEAGEHPDYQKILKLIEERDYRDSHRAVAPLKPAEDAIVIDTSSLNLQQVVDAVWEKIQHYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DHZ6</accession>
    <name>A0A1Y4DHZ6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_00480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57289">
        <property type="protein sequence ID" value="OUO57289"/>
        <property type="gene ID" value="B5F75_00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="91"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="347" mass="37782" checksum="D90D3E4DE99E1657" modified="2017-08-30" version="1">MELFAKPIFLLYLIPALLAAGLAAWLGLKLKNRLISILFGPLAYAKLTAGLRPVTRWRGVLFFLTLFFLFAALAGPQWGTEVIEAQGTFAQTVIAVDVSASMRAQDLKPDRLDNAKNMLRMLVSNLKDERIGVLAFTSQAFIQCPITTDADALTYFITSLQPDMLPVPGTSLAAPVQLAARMLSKYPGQKALILLTDGEDHSPDELKAAQETALKNGIRIIAIGIGTKEGTLIPSRTDSSGRVLEYKKDKEGKTVVSKLDENTLLELAKATGGVYIPYTTPAQVAAKVEAAVKGLDRSVSRTAARAAYKNRYAFPLIAAMLCLAGYLLWPRGRKPAESKEEKESQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DI68</accession>
    <name>A0A1Y4DI68_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_05460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56638">
        <property type="protein sequence ID" value="OUO56638"/>
        <property type="gene ID" value="B5F75_05460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="172" mass="18739" checksum="D8A7AEC757F05A73" modified="2017-08-30" version="1">MKKLIRITALLVIAGLLFSNWWRGRQIDKLAAQSGTLSDSQAARVVVKDNKLTATVRQPDGSVKTEVRYLPPEGHAEVVQPTDGPTEISVKRAGFTFRPAVQGLLGKELKAGLGARLVYFDRYGAGVGLDTDLEGYLFVDRRLDDLTGFLKNTTVGLYGGRGRLGVLVGVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIL5</accession>
    <name>A0A1Y4DIL5_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">B5F75_05955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">An273</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000004">
        <property type="protein sequence ID" value="OUO56160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56160">
        <property type="protein sequence ID" value="OUO56160"/>
        <property type="gene ID" value="B5F75_05955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OUO56160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="324" mass="35357" checksum="D33C552080A8D612" modified="2017-08-30" version="1">MFSIFTKIADALTAWMGLSPDTHLGSAIHFFIEDITKIFVLIYVLIFIISLFRSQLSPQKVREYLSGKNRWYGYFLAVFLGIVTPFCSCSSIPLFIGFITAGIPLGITMAFLISSPLVSEIATFMLISMKGAGVGVAAVYVLCGSLIAVLGGWLADRLHLERLCTYQAPQTVQPACSCSSPKTKSQQLRELTAYAHSFAWDTLKSIWLYVLAGLLVGALIHGYVPVAFLSKYLGADNPWAVPLASVIGAPMYANHVSVIPVIQALLLKGVPLGTALVILMSITAISLPEMMMLKKVLSVKMIALFTLYLIVSFICVGYILNWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIS9</accession>
    <name>A0A1Y4DIS9_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscL</name>
        <name evidence="11" type="ORF">B5F75_02050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57579">
        <property type="protein sequence ID" value="OUO57579"/>
        <property type="gene ID" value="B5F75_02050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OUO57579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="152" mass="16533" checksum="0CCF84E7946C4CC5" modified="2017-08-30" version="1">MFKNIYNEFKNFVMRGNVLDMAVGIIIGGAFTKIVNSMVADVMMPPLGLLMGKVNFSNWFIVLKQGDTTPGPYESLTAAQSAGATTINIGNFLNSIISFLIVAACIFALVKAMNKINKRKEDAAPTTKSCPYCCTEIPLEAVRCPHCTSELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIT0</accession>
    <name>A0A1Y4DIT0_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">murG</name>
        <name evidence="13" type="ORF">B5F75_03105</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56848">
        <property type="protein sequence ID" value="OUO56848"/>
        <property type="gene ID" value="B5F75_03105"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="6"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="188"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO56848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="362" mass="40627" checksum="5A44566039167453" modified="2017-08-30" version="1">MNRRFLIASGGTGGHFYPGLALGKELRRQGLAVLFIVRKNDPAAQILETHKLRYREIDFTGLPRSVNPLRHIRFVYKFFKSLLETRRIIKDFRPDAAIGTGGYISFPLIFTAHFMGIKTAVHDSNARLGLANKVCGKFADLFMLGLPVKKKIKNAVLTSTPIRREFAEKPDRNAVLEGLGLDPQKRTALIFGGSQGAKGLNAACAQIIRKLAPKLASWQFIHITGERWFGVIRQEYTGFSNVSVMPYSHEIYALMHVADLAVCRSGASTLAELMYCHLPAILVPFPHAAANHQFYNAKILANARCARLVPEDKNLAPHLAQVFERLTGKNRDLYYMRSAYSRLRIPNPMTAAKEIVRRLKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DIY9</accession>
    <name>A0A1Y4DIY9_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_03485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56918">
        <property type="protein sequence ID" value="OUO56918"/>
        <property type="gene ID" value="B5F75_03485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="23"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="91"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="125"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="200" mass="22106" checksum="54FE199C81030506" modified="2017-08-30" version="1">MLKKYLGALAAIGLAACGTLPTSSEYLLRGDGYFKDGKPQQALQAYTRALDLNPDNLEGYASRGSVYFFTGDYDRAEQDFLRVLQANPYQADAYTAYASTLAAKGDFHNALTVLNLAMQLKPNKPEIFFSRAGVYFMLGRYQEAIMDYTSVINLRPAAEVYNARGAAYEKLGQHELAQKDFEAAKSGKMPATLNVYSMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJC4</accession>
    <name>A0A1Y4DJC4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56420">
        <property type="protein sequence ID" value="OUO56420"/>
        <property type="gene ID" value="B5F75_04290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="149"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO56420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="297" mass="32457" checksum="3BB5B7D26F88AE96" modified="2017-08-30" version="1">MFNIAPVIAIWIAWFATAANLVISKAAVPYVTSALFILLACAVASVCFLPYIQKTNGWRILLDKKVWPQCLAMGTFGTALPMTIFMIALNYTTPVNGAILNQFEIIYSLILSAILLKERPTLRQIGGSLLILLGVGLLLWQAGTTVQLKGDLMIIGCLWMFQLSHIFAKKLPAQMPPQLIAAARALFAIPALAVLVAWLAAFQGPLQFESNATLWSMLVLCAVVNYFLGNTYWYQAIRHMDLSKATAIILSYPVMTFVLAVLLGQDKITAYKILGMVLAIGGAYIVTGLVKKQGETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJP7</accession>
    <name>A0A1Y4DJP7_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="7" type="ORF">B5F75_05035</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000003">
        <property type="protein sequence ID" value="OUO56560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56560">
        <property type="protein sequence ID" value="OUO56560"/>
        <property type="gene ID" value="B5F75_05035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="5">
        <location>
            <begin position="17"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="6">
        <location>
            <begin position="214"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="112"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO56560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="384" mass="41668" checksum="17B17AEEBCCCDF91" modified="2017-08-30" version="1">MKDLFMPADLFETKKAKIKVIGVGGGGGNAINHMVSSGLKDVDFIAVNTDAQDLRRNRAPYLVQVGEKITKGLGVGGDPEKGKKAAEESAEKLKLIIGQCDLLFITAGMGGGTGTGVAPYLAKLAKDLYGDDLLVIGVVTRPFNFEGYVREKQADEGIKEMQKYVDSMIIVPNEKLFANIDPETSSKDAFKMVDEVLLQAVKGISEVITQPGEVNIDFNDVRKVMCHSHKSLIGIGEASGPGRHLQAVKKAISSPLLENADIRGAKGFIVHFSAEENLTLLEQGEVMNLIRQYASNDSIIMFGYSYDSSLNGMFKVTVIATGFSAEKANMFSARRPLPAEMAGSTSIKKPSVQEVFASFHEPKQTDAEDAMLIPAYLRRKKNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DJZ8</accession>
    <name>A0A1Y4DJZ8_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_00255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57248">
        <property type="protein sequence ID" value="OUO57248"/>
        <property type="gene ID" value="B5F75_00255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="137" mass="15190" checksum="3943571A3A22CAC1" modified="2017-08-30" version="1">MNTEQNKNAMKKFETMINTADLNLANELISANAQFITPVSPTPLIGGEGYLSVVHFLRSGFSNVQWKAEEMVAEKNIVAVSWMCTGTHDGEFLGIKPTHKTFSARFMNFYYFNEDGKIINDVAAEGMIAIMKAIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKL6</accession>
    <name>A0A1Y4DKL6_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_01465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57468">
        <property type="protein sequence ID" value="OUO57468"/>
        <property type="gene ID" value="B5F75_01465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="253" mass="28732" checksum="AA1680667778BEEE" modified="2017-08-30" version="1">MNTPKSKNRWSKTQIWTFVLAVLAVCGGAFYGGYYYRQAHQFKQAEQIMSSIRLEQEKQCAYHKHYTTNAKAFSRFFPKRGHKHFKYVFKPTGMEIHRKGRHGYVLKMPSYEDGRLCCDTPDSCRRLKGRFPFCADLKARADYVSGEECSPFPQRPLCKGPSVRRCGCQGKGIQLRMCDAETNTWGEWGKCSIADTCDCSAVSGMKPAAQTQVCNGCGAQSRDFRCNTQTGQWEAEAWSPCSRRPEECAPTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKM5</accession>
    <name>A0A1Y4DKM5_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="10">R protein</shortName>
            <ecNumber evidence="10">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">B5F75_01525</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="10"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57478">
        <property type="protein sequence ID" value="OUO57478"/>
        <property type="gene ID" value="B5F75_01525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="288"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="1107" mass="126463" checksum="344C2F442279098F" modified="2017-08-30" version="1">MAALKEFNGRYFESEFESAFVSFLEEEGWIYSAGNKLARTKRDVLIANDFKKFLADTQTDLTEEEIAQIFDGVRLAGGESDFATLHKVYGWMVNGVQFTPQNGLARMVPLIDFERPDKNIFRVVNQFAVEYTNNGQKECRRPDLVLFVNGLPLCVIELKNPADERATVYDAWEQITIRYWRDIPHLLHYCPLACISDGVKTRLGTVRTPYEHFYAWRRVNEGDKISSLPFAETQTMIKGVYNPVRFLEIFRDYIHFQDSIYDKDEKEIVCRYPQFFAARLLKRSIVKSVVSKSGKGGTYFGATGCGKTYTMAFLARQLALRCTDVPEIGSPTIILIVDRDDLQKQGARLFTKSTEFLNLGAVSIVKNRHVLREELKARQSGGFYICTIQKFCDRAEDKIGLINDRQNIICFSDEAHRTQLEHSREIKFSKDADENMKAVISKPYAKVLKEAFPHATFVGFTGTPIAETYQTFGDEIDRYTMDQAVADGLTVPIKYHPRIAKVLLNKEKVQEIESYYKKCADDGATAEDVAASKRAMSSMEVILGEPSRLERLAVDIHDHYVAACANDPDRVQKAMIVCSSRAIAYDLLLKFKEKYPEWFVAKKVPDGVTATAEELRELKPMPFMAMVASVGSNDKPEMYNYLGGVKNDKRSENLDTAFKQDKSNFRIVIVVDMWITGFDVPSLTYMYNDKPLKKHLLIQTISRVNRKYPGKEYGLIVDYIGIRDNMREAMKIYGGDSSVAPTADDVTQATKAFREELEILKKMFSGYDLTPFLSLDCEPGKRYSLLSKAAEYVFTSTQELQQEGKKKAQKVSFKTYFLSTVKRMRAAFDVCQPSGNLGEEENALAQCFMAVAGFVRKMSGTSDVDTDTMNRIVAKMVEEALKYNQVESVLESGEEEDLFSPEYFEKLSDVKMPATKLELLVKMLRKQIKEYSRVNQVAAKTFQEMLEKTIAEYHERRKTLTLEEAGETQEQASENIIKSATEQALDILRKMQENKESFRKLGLTFEEKAFYDILLSLRDQHNFEYGTDKKVNGLVINDKCKALAKKVKEIIDTQSSFADWLNNQRVRDQLKLEIKICLIKNGYPPQYSPEVFKKVMQQVENFEENAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKT3</accession>
    <name>A0A1Y4DKT3_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GTPase Obg</fullName>
            <ecNumber evidence="7">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">obg</name>
        <name evidence="12" type="ORF">B5F75_07055</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="7"/>
    <dbReference type="EMBL" id="NFJD01000005">
        <property type="protein sequence ID" value="OUO56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56031">
        <property type="protein sequence ID" value="OUO56031"/>
        <property type="gene ID" value="B5F75_07055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="11">
        <location>
            <begin position="4"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="9">
        <location>
            <begin position="161"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="10">
        <location>
            <begin position="344"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="421"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="167"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="192"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="310"/>
            <end position="312"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="459" mass="50283" checksum="DB46067A270AA55D" modified="2017-08-30" version="1">MQSGSFLDRVKIYVTAGKGGDGCLSFRREKFIEFGGPNGGCGGKGGDVILRAEPNLTTLLELAYNPHIEAQNGEKGGTYNKTGRAGEDRIVLVPCGTIVKQDGHILADLTKPGQEFTVAKGGMGGRGNQSFKTRNNTAPHIAENGQPGEEVTLILELKVLADLGLVGFPNAGKSTFLSRISAARPRIADYPFTTLNPNLGITLHKNVSFATADIPGIIEGASEGKGLGYQFLKHIERTRVLLHLVDPEGFDGMNAEKSVKVIENELKTFDKKLFEKPRIIVVNKMDLPSAQKAYETLKKKFKKHKVMLMSAATGEGVNAVLDEVVKILASTPVEMPLEPEQTAAVHKVEPIFSISRDEEEVIHITGKKVVEFIAMTNFNQPEAVARLRGIFKKIGLEKALLKFGVQDGDTLVVGGREFEWNGDFDNEAPTAPEHAGYKRRETKQERLEKRRARRQAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DKY1</accession>
    <name>A0A1Y4DKY1_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57588">
        <property type="protein sequence ID" value="OUO57588"/>
        <property type="gene ID" value="B5F75_02095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010466">
        <property type="entry name" value="DUF1058"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06347">
        <property type="entry name" value="SH3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012305664" description="SH3b domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="94"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="155" mass="17343" checksum="D99F70486C4DDC9D" modified="2017-08-30" version="1">MKKIIALCTLMLLVSAPVFAQKYASVNAKRANIRACAGTKCAIKWYAWRYTPVIMVKTNEDKSWVLVKDFEGYSGWISASLLSPNGGMSAKVDLNVRKSPSSNADIVCTVEKGYPFKYISKKGSWIQVEDDPADPKDGKCEGWVYNVNLWGFFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DL61</accession>
    <name>A0A1Y4DL61_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_02520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57668">
        <property type="protein sequence ID" value="OUO57668"/>
        <property type="gene ID" value="B5F75_02520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012395837" description="Peptidase S1 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="2">
        <location>
            <begin position="155"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="413" mass="45600" checksum="88DD61B8D03C5087" modified="2017-08-30" version="1">MQKNILLWVLVFSLAHTPFAYGQKTLKPVFKSLGKVAAQKAPQTAAKALLPASPAAAAALAKTTAPHQNLPALPLPPLPLTTQETARQLQKQVNFALVIALAKQQEQTRRKMAAFDTQLRQRVGTLRNPFLQDFIPLEGTAFFIEEEYQGKKYLWGVTAAHMVDYVGPDIHLRLSLDVGLSYDIPVTVVAKGNTGMADIAIFKINEDVSDLVLPFTLAKREPKPNEVLRSYGFFEGDFHVVPNRKVLQSTPGRIVTSFEFGNHERAGACGGPLINEQNELVGIHCGSSRSKQESYAVPISFLKDLLEAAHHNGIKERDLVLNGRTIGKINIDEYIYSVSVKKLGITLRTVTPWREESRVDYNHLENLIELPHSGVLEIAIVKGGTIQTGQTKATSQKLISVNLRTGSSFLEYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DLR4</accession>
    <name>A0A1Y4DLR4_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57240">
        <property type="protein sequence ID" value="OUO57240"/>
        <property type="gene ID" value="B5F75_00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012305663" evidence="1">
        <location>
            <begin position="20"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="947" mass="105015" checksum="42756EE481B05F6B" modified="2017-08-30" version="1">MKRILSLLTGVLICLPAAAQLPTKAVTGAVKALEGGAKKLPASARLTARGLRPLPVAKAAVPPVGVSAGQPLVDVTALEQKVAQQVSLKVGLESPAAWVRRKAAAKQVPDGILQALFAVPSQQERTALLQNEFLTLTLQRGVSPSAQQAAQALEAYRRDLIAHPKGFSGIKNLTAANDAVLESAGGLLADMAGIGFYGTAQDAALLVNAYQTAASSELEPVVFTAAARALLRLRAYGELEQVMALAQPSAARSAAETFIRKHHLPVSVPPKPAAAQAQRDWNKLAEPLGRASRLNRLQLDLSERATETWMKMTVRLLPQETKAAARPTVLQQPISLHIAPSLQAQQLPGVSSPAPQERASYGFFQRSQPSSGGVLYSGLPVMDWLGKAKKWFSPAKQTPQQPAAAASSDEYNPVVPVLRHTPRTGLMSNQYPSGLKDEESIIRDWLEYFKNGYFRPRNQVEAIEGMSAAKANNVMEYLYYMPLEEAEKVILNPIRETGRLPDFMYDDRLIAGTKRLPAGYYKNKFNENVTRFVELAEEDGSIYTHNVELKDLATSMADYSFKQGFRYTNDPQMTAGLRHNWKELVAEIRKPGLRADRDLINALWRKPVKLDGGKTVSLKEYFTQTRPTAFFKEGRMPEFFLNSNKWVAWENERRNLAAAEYIDQSTPDHLSWLERVQNWFVLGKTSSYLTLEQFGNIMASQYRKSFGAAVRTNEQEYTHGVVLEDATPSSMTVKINNFDKVGGVCQMSFSEGGYMGRVKPGYDGTSTVSRFDFIRFPKVPVVTFDFGTLKPHIVTLESVPYLRDLKEPDLDQVRASTMVGDGLDPTRDLLGVREAEAALFKIPHLKATLYPRARLEGYDQAKPKYLDGGGLAGYLTLFTPDFYPIKKIKRLRFKGLKPYIETQYFIRREVAALAGLIHRDRLTFTEQVQDRIVPDKAAPARPDDSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM32</accession>
    <name>A0A1Y4DM32_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">B5F75_00830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57350">
        <property type="protein sequence ID" value="OUO57350"/>
        <property type="gene ID" value="B5F75_00830"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="239"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OUO57350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="368" mass="40101" checksum="609564AA17F2D43C" modified="2017-08-30" version="1">MSMPILRPTVAEVDLKKLARNMHKVHAQAGAGVKVLTVLKANAYGHGAEKLGLFLQQNHLSDFFGTASVEEGIALRQAGVTLPILVLGSLYPFEVFEYAIKNHLAVTIASLDAAKAVSQIAAKLGQKAFCHVKQDTGMGRIGTRRGGVFNVIDFLAHDPHVVLDGLYTHLSSVETDPAYTEEQIGYYRDTLTNVQLHHIHINHCHVAASAAIVARPDVRYDMVRTGHSAFGLEKGFEPILSLKTRVVYVKDVPAGSSISYNRSFIAPRPMKVATLPLGYGDGYLRALSNKGEILIRGKRCRVLGNVTMDMLMVDITQAGPVTVGDEAVAVGRQGDEEVTFAELAQKAGTIDYELCTLLMPRVPRIYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DM46</accession>
    <name>A0A1Y4DM46_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_00890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57360">
        <property type="protein sequence ID" value="OUO57360"/>
        <property type="gene ID" value="B5F75_00890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO57360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="237" mass="28306" checksum="D9D0D2E56BD4EF2D" modified="2017-08-30" version="1">MIVFWRLFLAFFLTDFVFFHKTINRMEEQNRPRAIALHAGVFLAWAFLLCYGYLTMPWPFLGFWHIPGWLCILLFCVFLVFADRFFQFGGKMRHGHVLTFFTKTIVNLLFLFLCVPFKVLYETGNFFAEPWIIFCVGLVTATRVLGWFIFSVEQDRYGRDYPTFDERWLLTMMCAIFFLIMLLPGWRWVVLLLVWFAACLYARKIRLMDISNMAFYVGAFGAAFIGFLVRLRFYLNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DN19</accession>
    <name>A0A1Y4DN19_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">B5F75_02910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO56811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO56811">
        <property type="protein sequence ID" value="OUO56811"/>
        <property type="gene ID" value="B5F75_02910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012847894" evidence="1">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OUO56811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="104" mass="11833" checksum="72392A97E50DA2F6" modified="2017-08-30" version="1">MKKYILTMTLLACAALAGAGEIADDCTYNGIPLYGRVQVVEFMADFTVQKVPFRPDLRVQNTVFSPNKCGEWQFVEFMPDFTIQYVEFSPDFTIQMVDFFPGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNN2</accession>
    <name>A0A1Y4DNN2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Trigger factor</fullName>
            <shortName evidence="9">TF</shortName>
            <ecNumber evidence="3 9">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">PPIase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tig</name>
        <name evidence="12" type="ORF">B5F75_03900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="9">About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.</text>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FKBP-type PPIase family. Tig subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3 9"/>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57001">
        <property type="protein sequence ID" value="OUO57001"/>
        <property type="gene ID" value="B5F75_03900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00303">
        <property type="entry name" value="Trigger_factor_Tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005215">
        <property type="entry name" value="Trig_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008880">
        <property type="entry name" value="Trigger_fac_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037041">
        <property type="entry name" value="Trigger_fac_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008881">
        <property type="entry name" value="Trigger_fac_ribosome-bd_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036611">
        <property type="entry name" value="Trigger_fac_ribosome-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30560">
        <property type="entry name" value="PTHR30560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05698">
        <property type="entry name" value="Trigger_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05697">
        <property type="entry name" value="Trigger_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003095">
        <property type="entry name" value="Trigger_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102735">
        <property type="entry name" value="SSF102735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00115">
        <property type="entry name" value="tig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="Trigger_N" evidence="10">
        <location>
            <begin position="24"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Trigger_C" evidence="11">
        <location>
            <begin position="277"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OUO57001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="439" mass="48830" checksum="4B7EB2596E3D9B94" modified="2017-08-30" version="1">MSDTNRSELSMSIFKTAQSGEVKTQQVKKEGCRVTLSVEASPELVTKSFQNAAVQVQSRAQMQGFRAGKVPLDLVKQNFAGHIKERALDLTVKAAINAAITDAKLDAVAVPTLTKADFMNFAEGKAFPFEIAVDVAPEFEVKDYKGIEIAKKPETATEQDVAENLNRVLDANARLESAAEGAVIDDKCYAVIHYSGKRNGTDDYKLSADSELVDMSAPQTMPGLAEGIKGLKKGDVKDIETKEGNDTISYHVTVDDIKNKIVPALDDSFAKDMGFDTLDALKAKVKESLDEEAKQNARRDEVAQIENHLVKMNQFDLPQSLVEEYTESSLNNFVRSMTQLKPEQLTADQKKAFEERIRPSVEKDLRIGYIVHAIAKKENLEATEADWKAELDKSIAANSQNKEDEKKIKAFFNERKAHILATLSERKVFDFIKEQAKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNQ1</accession>
    <name>A0A1Y4DNQ1_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">B5F75_04025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57021">
        <property type="protein sequence ID" value="OUO57021"/>
        <property type="gene ID" value="B5F75_04025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="OUO57021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="161" mass="17641" checksum="C558D205C93B934E" modified="2017-08-30" version="1">MGGIWKAGGQVISSAASLLGDRKSEIDYYDALARDADRQARYTAAASERQATYLFKSAAEKGRELYENYRQTAGSQKTALAASGLTSSSATVQTILKNSRFNALLDQQALQESLQDALYENNVSAAEHIYSLNETAAQYRRAAQNRGSWWKLGSNILSLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DNT0</accession>
    <name>A0A1Y4DNT0_9BACT</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">B5F75_04175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">An273</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000002">
        <property type="protein sequence ID" value="OUO57051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57051">
        <property type="protein sequence ID" value="OUO57051"/>
        <property type="gene ID" value="B5F75_04175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OUO57051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="77" mass="9068" checksum="E9406BEC983F06C2" modified="2017-08-30" version="1">MIFIARAVVLIVLLVWVIGIFYFYSQVKETERQIAELKQKQQREEELLRRRAIYQRASMEQQAVQSGVQNAVDALKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DPU2</accession>
    <name>A0A1Y4DPU2_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">B5F75_01000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">An273</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57381">
        <property type="protein sequence ID" value="OUO57381"/>
        <property type="gene ID" value="B5F75_01000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="107"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OUO57381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="295" mass="34085" checksum="B0621F8A6DFDDD31" modified="2017-08-30" version="1">MENFLLEDFRNHLTFERQLSKNTVASYGSDVESFLEYCQANEKDPLQITPDFLDQYTYQLREVEKLAPSSVFRKLEAVKCFYKFLLIEEKIKDDPTRFLKSPKLAQKIPTQLTREEMDRLLSYPAETLAEIRTVTIIELLYAAGLRVSELINLRLENVNTQEGWVLAFGKGGKQRFVPIHPRACERIKQYLAVREAHFADKNVGSEVFLNKNGKKISRISVWKDLSALGRKANISQPLHPHLFRHTFASHMLQGGADLRSLQEMLGHANLTTTQIYTHLDVSDLKEKHKKFHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-08-30" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A1Y4DQF6</accession>
    <name>A0A1Y4DQF6_9BACT</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pheS</name>
        <name evidence="15" type="ORF">B5F75_02170</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Elusimicrobium sp. An273</name>
        <dbReference type="NCBI Taxonomy" id="1965617"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobia</taxon>
            <taxon>Elusimicrobiales</taxon>
            <taxon>Elusimicrobiaceae</taxon>
            <taxon>Elusimicrobium</taxon>
            <taxon>unclassified Elusimicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-04" db="EMBL/GenBank/DDBJ databases">
            <title>Function of individual gut microbiota members based on whole genome sequencing of pure cultures obtained from chicken caecum.</title>
            <authorList>
                <person name="Medvecky M."/>
                <person name="Cejkova D."/>
                <person name="Polansky O."/>
                <person name="Karasova D."/>
                <person name="Kubasova T."/>
                <person name="Cizek A."/>
                <person name="Rychlik I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">An273</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="NFJD01000001">
        <property type="protein sequence ID" value="OUO57601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OUO57601">
        <property type="protein sequence ID" value="OUO57601"/>
        <property type="gene ID" value="B5F75_02170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000196368">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="124"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OUO57601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000196368"/>
        </source>
    </evidence>
    <sequence length="346" mass="38775" checksum="EC4ECB6861DC2FCC" modified="2017-08-30" version="1">MTIQEFKSACSTIEQEYKAKIGQAADLAAVEELRVAALGRKGALTELLKGLKDFSIEEKKEAGPLGNALKAALTAAFDEKTEFFAAKEINDELNKVNLDLTLPGYPVAKGHRHPLSVAQDRMTDILSRLGFEWAEGPWVEDEKHNFDLLNIPLHHPARDAQDTFFVDGKMPLVLRTHTSNVQSRYMEKHKPPLRIMAPGRVFRNDSLDATHSPVFHQIEGLYVDKHVSLADLKSDLTAFMKGLFGNKAEIRFRPSFFPFTEPSVEVDVKCVFCQGKGCNVCKGNGWIEMLGAGVVHPNVLRNCGIDPEVYSGYAFGMGVERLAMMMLNIKDIRTFYENDLRVLKQF</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>